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Source1

{
  "resourceType": "ConceptMap",
  "id": "dm-immunological-data-to-fhir",
  "text": {
    "status": "generated",
    "div": "<!-- snip (see above) -->"
  },
  "url": "https://hl7.eu/fhir/ig/hl7.eu.fhir.protect-child/ConceptMap/dm-immunological-data-to-fhir",
  "version": "0.1.0-ci-build",
  "name": "DmImmunologicalDataToFhir",
  "title": "DM immunological_data columns → FHIR codes",
  "status": "draft",
  "experimental": true,
  "date": "2026-09-28T06:51:47+00:00",
  "publisher": "Protect Child",
  "contact": [
    {
      "name": "Protect Child",
      "telecom": [
        {
          "system": "url",
          "value": "https://protect-child.eu/"
        }
      ]
    }
  ],
  "description": "Maps each result column of the DMv1.2 immunological_data table to the code of the resource it becomes. The row itself becomes an ImmunologicalDataReport, and the biopsy columns a GraftBiopsy carrying the same immunological_data_id. Three columns have no code of their own: `if` becomes GraftBiopsy.conclusion, `c4d` becomes C4dStain.note, and the free text of `pre_transplant_anti_hla_dsa` becomes AntiHlaAntibodyScreen.note. The HLA columns are marked `wider` because each maps to a locus code shared by both allele columns: one Observation per allele replaces the ordered pair of slots.",
  "sourceCanonical": "https://hl7.eu/fhir/ig/hl7.eu.fhir.protect-child/ValueSet/dm-immunological-data-variable-vs",
  "group": [
    {
      "source": "https://hl7.eu/fhir/ig/hl7.eu.fhir.protect-child/CodeSystem/dm-variable-cs",
      "target": "http://loinc.org",
      "element": [
        {
          "code": "immunological_data.blood_group",
          "target": [
            {
              "code": "883-9",
              "display": "ABO group [Type] in Blood",
              "equivalence": "equivalent",
              "comment": "BloodGroupObservation.code"
            }
          ]
        },
        {
          "code": "immunological_data.rh_factor",
          "target": [
            {
              "code": "10331-7",
              "display": "Rh [Type] in Blood",
              "equivalence": "equivalent",
              "comment": "BloodGroupObservation.code"
            }
          ]
        },
        {
          "code": "immunological_data.hla_a_1",
          "target": [
            {
              "code": "13298-5",
              "display": "HLA-A [Type]",
              "equivalence": "wider",
              "comment": "HlaTyping.code. One Observation per allele: hla_a_1 and hla_a_2 become two HlaTyping resources with the same code, since HLA alleles are not ordered. Use 57290-9 or 78014-8 where the typing resolution is known."
            }
          ]
        },
        {
          "code": "immunological_data.hla_a_2",
          "target": [
            {
              "code": "13298-5",
              "display": "HLA-A [Type]",
              "equivalence": "wider",
              "comment": "HlaTyping.code. See hla_a_1."
            }
          ]
        },
        {
          "code": "immunological_data.hla_b_1",
          "target": [
            {
              "code": "13299-3",
              "display": "HLA-B [Type]",
              "equivalence": "wider",
              "comment": "HlaTyping.code. Use 57291-7 or 78015-5 where the resolution is known."
            }
          ]
        },
        {
          "code": "immunological_data.hla_b_2",
          "target": [
            {
              "code": "13299-3",
              "display": "HLA-B [Type]",
              "equivalence": "wider",
              "comment": "HlaTyping.code. See hla_b_1."
            }
          ]
        },
        {
          "code": "immunological_data.hla_c_1",
          "target": [
            {
              "code": "13302-5",
              "display": "HLA-C [Type]",
              "equivalence": "wider",
              "comment": "HlaTyping.code. Use 77636-9 or 96636-6 where the resolution is known."
            }
          ]
        },
        {
          "code": "immunological_data.hla_c_2",
          "target": [
            {
              "code": "13302-5",
              "display": "HLA-C [Type]",
              "equivalence": "wider",
              "comment": "HlaTyping.code. See hla_c_1."
            }
          ]
        },
        {
          "code": "immunological_data.hla_drb1_1",
          "target": [
            {
              "code": "57298-2",
              "display": "HLA-DRB1 [Type]",
              "equivalence": "wider",
              "comment": "HlaTyping.code. Use 57293-3 or 96664-8 where the resolution is known."
            }
          ]
        },
        {
          "code": "immunological_data.hla_drb1_2",
          "target": [
            {
              "code": "57298-2",
              "display": "HLA-DRB1 [Type]",
              "equivalence": "wider",
              "comment": "HlaTyping.code. See hla_drb1_1."
            }
          ]
        },
        {
          "code": "immunological_data.hla_dp_1",
          "target": [
            {
              "code": "12285-3",
              "display": "HLA-DP [Type]",
              "equivalence": "wider",
              "comment": "HlaTyping.code. The DM values are DPB1 alleles at an unrecorded resolution, so the ambiguous DP code is the safe migration target; new data SHOULD use 59017-4 (DPB1 high resolution) or 96648-1 (low resolution)."
            }
          ]
        },
        {
          "code": "immunological_data.hla_dp_2",
          "target": [
            {
              "code": "12285-3",
              "display": "HLA-DP [Type]",
              "equivalence": "wider",
              "comment": "HlaTyping.code. See hla_dp_1."
            }
          ]
        },
        {
          "code": "immunological_data.hla_dqb1_1",
          "target": [
            {
              "code": "53938-7",
              "display": "HLA-DQB1 [Type]",
              "equivalence": "wider",
              "comment": "HlaTyping.code. Use 57299-0 or 78017-1 where the resolution is known."
            }
          ]
        },
        {
          "code": "immunological_data.hla_dqb1_2",
          "target": [
            {
              "code": "53938-7",
              "display": "HLA-DQB1 [Type]",
              "equivalence": "wider",
              "comment": "HlaTyping.code. See hla_dqb1_1."
            }
          ]
        },
        {
          "code": "immunological_data.anti_hla_antibodies",
          "target": [
            {
              "code": "44534-6",
              "display": "HLA Ab [Presence] in Serum",
              "equivalence": "equivalent",
              "comment": "AntiHlaAntibodyScreen.code. The DM boolean becomes a Positive or Negative result, so a negative screen is recorded rather than inferred from absence."
            }
          ]
        },
        {
          "code": "immunological_data.pre_transplant_anti_hla_dsa",
          "target": [
            {
              "code": "107913-6",
              "display": "HLA-A and B and C (class I) and HLA-DP and DQ and DR (class II) Ab.IgG donor specific [Presence] in Serum or Plasma",
              "equivalence": "narrower",
              "comment": "AntiHlaAntibodyScreen.code, with the DM free text in AntiHlaAntibodyScreen.note."
            }
          ]
        },
        {
          "code": "immunological_data.antibody_type",
          "target": [
            {
              "code": "107914-4",
              "display": "HLA-A and B and C (class I) and HLA-DP and DQ and DR (class II) Ab.IgG donor specific [Identifier] in Serum or Plasma",
              "equivalence": "narrower",
              "comment": "AntiHlaAntibody.code; the target HLA specificity becomes AntiHlaAntibody.valueString, one Observation per antibody. Use 98006-0 for an antibody that is not donor-specific."
            }
          ]
        },
        {
          "code": "immunological_data.ihc_if_c4d",
          "target": [
            {
              "code": "49461-7",
              "display": "C4d Ag [Presence] in Tissue by Immune stain",
              "equivalence": "equivalent",
              "comment": "C4dStain.code. The DM boolean maps to BanffC4dScoreCS c4d-0 (false) or c4d-1..c4d-3 (true)."
            }
          ]
        },
        {
          "code": "immunological_data.anca",
          "target": [
            {
              "code": "17351-8",
              "display": "Neutrophil cytoplasmic Ab [Presence] in Serum",
              "equivalence": "equivalent",
              "comment": "AncaObservation.code. The DM boolean becomes Positive or Negative."
            }
          ]
        }
      ]
    },
    {
      "source": "https://hl7.eu/fhir/ig/hl7.eu.fhir.protect-child/CodeSystem/dm-variable-cs",
      "target": "https://hl7.eu/fhir/ig/hl7.eu.fhir.protect-child/CodeSystem/imm-data-component-cs",
      "element": [
        {
          "code": "immunological_data.post_transplant_ab_anti_hla_dsa_class",
          "target": [
            {
              "code": "hla-class",
              "display": "HLA class of the antibody",
              "equivalence": "equivalent",
              "comment": "AntiHlaAntibody.component[hla_class].code. LOINC has no component code for antibody class."
            }
          ]
        },
        {
          "code": "immunological_data.mfi",
          "target": [
            {
              "code": "mfi-category",
              "display": "MFI band",
              "equivalence": "equivalent",
              "comment": "AntiHlaAntibody.component[mfi_category].code. The measured MFI, where the laboratory reports it, goes in component[mfi_value]."
            }
          ]
        }
      ]
    },
    {
      "source": "https://hl7.eu/fhir/ig/hl7.eu.fhir.protect-child/CodeSystem/dm-variable-cs",
      "target": "https://hl7.eu/fhir/ig/hl7.eu.fhir.protect-child/CodeSystem/graft-pathology-cs",
      "element": [
        {
          "code": "immunological_data.banff_category",
          "target": [
            {
              "code": "banff-category",
              "display": "Banff diagnostic category",
              "equivalence": "equivalent",
              "comment": "BanffAssessment.code, on the GraftBiopsy built from the same DM row. Neither LOINC nor SNOMED CT carries the Banff classification."
            }
          ]
        }
      ]
    }
  ]
}