FHIR IG Statistics: StructureDefinition/mii-pr-mtb-hrd-score

Resources that use this resource

Resources that this resource uses

Narrative

No narrative content found in resource

Source

{
  "resourceType": "StructureDefinition",
  "id": "mii-pr-mtb-hrd-score",
  "url": "https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/StructureDefinition/mii-pr-mtb-hrd-score",
  "version": "2024.0.0-ballot",
  "name": "MII_PR_MTB_HRD_Score",
  "title": "MII PR MTB HRD Score",
  "status": "draft",
  "publisher": "Medizininformatik Initiative",
  "contact": [
    {
      "telecom": [
        {
          "system": "url",
          "value": "https://www.medizininformatik-initiative.de"
        }
      ]
    }
  ],
  "description": "Der HRD-Score, welcher den Grad der homologen Rekombinationsdefizienz bei Zellen beschreibt.",
  "fhirVersion": "4.0.1",
  "kind": "resource",
  "abstract": false,
  "type": "Observation",
  "baseDefinition": "https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/StructureDefinition/mii-pr-mtb-molekularer-biomarker",
  "derivation": "constraint",
  "differential": {
    "element": [
      {
        "id": "Observation.identifier",
        "path": "Observation.identifier",
        "mustSupport": true
      },
      {
        "id": "Observation.category",
        "path": "Observation.category",
        "mustSupport": true
      },
      {
        "id": "Observation.code",
        "path": "Observation.code",
        "patternCodeableConcept": {
          "coding": [
            {
              "code": "107286-7",
              "system": "http://loinc.org"
            }
          ]
        }
      },
      {
        "id": "Observation.subject",
        "path": "Observation.subject",
        "min": 1,
        "type": [
          {
            "code": "Reference",
            "targetProfile": [
              "http://hl7.org/fhir/StructureDefinition/Patient",
              "http://hl7.org/fhir/StructureDefinition/Group"
            ]
          }
        ],
        "mustSupport": true
      },
      {
        "id": "Observation.encounter",
        "path": "Observation.encounter",
        "mustSupport": true
      },
      {
        "id": "Observation.value[x]",
        "path": "Observation.value[x]",
        "short": "HRD-Score",
        "definition": "HRD-Score als Summe der LOH, TAI und LST-Werte",
        "type": [
          {
            "code": "integer"
          }
        ],
        "mustSupport": true
      },
      {
        "id": "Observation.interpretation",
        "path": "Observation.interpretation",
        "mustSupport": true,
        "binding": {
          "strength": "required",
          "valueSet": "http://hl7.org/fhir/uv/genomics-reporting/ValueSet/high-low-codes-vs"
        }
      },
      {
        "id": "Observation.specimen",
        "path": "Observation.specimen",
        "mustSupport": true
      },
      {
        "id": "Observation.component",
        "path": "Observation.component",
        "slicing": {
          "discriminator": [
            {
              "type": "value",
              "path": "code"
            }
          ],
          "rules": "closed",
          "description": "Elements of the HRD Score",
          "ordered": false
        }
      },
      {
        "id": "Observation.component:LOH",
        "path": "Observation.component",
        "sliceName": "LOH",
        "short": "Loss of heterozygosity",
        "min": 0,
        "max": "1",
        "mustSupport": true
      },
      {
        "id": "Observation.component:LOH.code",
        "path": "Observation.component.code",
        "patternCodeableConcept": {
          "coding": [
            {
              "code": "C18016",
              "system": "https://nih-ncpi.github.io/ncpi-fhir-ig/CodeSystem-ncit.html",
              "display": "Loss of Heterozygosity"
            }
          ]
        }
      },
      {
        "id": "Observation.component:LOH.value[x]",
        "path": "Observation.component.value[x]",
        "type": [
          {
            "code": "integer"
          }
        ],
        "mustSupport": true
      },
      {
        "id": "Observation.component:TAI",
        "path": "Observation.component",
        "sliceName": "TAI",
        "short": "Telomeric allelic imbalance",
        "min": 0,
        "max": "1",
        "mustSupport": true
      },
      {
        "id": "Observation.component:TAI.code",
        "path": "Observation.component.code",
        "patternCodeableConcept": {
          "coding": [
            {
              "code": "C129774",
              "system": "https://nih-ncpi.github.io/ncpi-fhir-ig/CodeSystem-ncit.html",
              "display": "Telomeric Allelic Imbalance Region"
            }
          ]
        }
      },
      {
        "id": "Observation.component:TAI.value[x]",
        "path": "Observation.component.value[x]",
        "type": [
          {
            "code": "integer"
          }
        ],
        "mustSupport": true
      },
      {
        "id": "Observation.component:LST",
        "path": "Observation.component",
        "sliceName": "LST",
        "short": "Large-scale state transitions",
        "min": 0,
        "max": "1",
        "mustSupport": true
      },
      {
        "id": "Observation.component:LST.code",
        "path": "Observation.component.code",
        "patternCodeableConcept": {
          "coding": [
            {
              "code": "C120466",
              "system": "https://nih-ncpi.github.io/ncpi-fhir-ig/CodeSystem-ncit.html",
              "display": "Large-Scale State Transition"
            }
          ]
        }
      },
      {
        "id": "Observation.component:LST.value[x]",
        "path": "Observation.component.value[x]",
        "type": [
          {
            "code": "integer"
          }
        ],
        "mustSupport": true
      }
    ]
  }
}