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Source1

{
  "resourceType": "ValueSet",
  "id": "2.16.840.1.113762.1.4.1196.491",
  "meta": {
    "versionId": "11",
    "lastUpdated": "2023-12-21T17:43:03.000-05:00",
    "profile": [
      "http://hl7.org/fhir/StructureDefinition/shareablevalueset",
      "http://hl7.org/fhir/us/cqfmeasures/StructureDefinition/computable-valueset-cqfm",
      "http://hl7.org/fhir/us/cqfmeasures/StructureDefinition/publishable-valueset-cqfm"
    ]
  },
  "extension": [
    {
      "url": "http://hl7.org/fhir/StructureDefinition/valueset-author",
      "valueContactDetail": {
        "name": "Elimu Informatics Author"
      }
    },
    {
      "url": "http://hl7.org/fhir/StructureDefinition/resource-lastReviewDate",
      "valueDate": "2025-03-10"
    },
    {
      "url": "http://hl7.org/fhir/StructureDefinition/valueset-effectiveDate",
      "valueDate": "2021-09-09"
    }
  ],
  "url": "http://cts.nlm.nih.gov/fhir/ValueSet/2.16.840.1.113762.1.4.1196.491",
  "identifier": [
    {
      "system": "urn:ietf:rfc:3986",
      "value": "urn:oid:2.16.840.1.113762.1.4.1196.491"
    }
  ],
  "version": "20210909",
  "name": "MediumDoseICSFormoterolPreparations",
  "title": "Medium Dose ICS Formoterol Preparations",
  "status": "active",
  "experimental": false,
  "date": "2021-09-09T01:00:51-04:00",
  "publisher": "NHLBI Implementation Science and Health Care Innovation Steward",
  "jurisdiction": [
    {
      "coding": [
        {
          "system": "urn:iso:std:iso:3166",
          "code": "US"
        }
      ]
    }
  ],
  "purpose": "(Clinical Focus: This valueset contains oral inhaled corticosteroid preparations in combination with formoterol that are used for medium-dose single maintenance and reliever therapy (SMART) in asthmatic adults and children at least 4 years old.),(Data Element Scope: FHIR \nMedicationStatement.medicationCodeableConcept, MedicationRequest.medicationCodeableConcept),(Inclusion Criteria: Includes oral ICS-formoterol preparations that might reasonably be used to treat asthmatic children age 4+ years and adults with daily and PRN combination medium-dose ICS-formoterol as per Step 4 in the NHLBI NAEPP 2020 Focused Updates to the Asthma Management Guidelines. The medium-dose range refers to the ICS component as per the NHLBI NAEPP EPR3 Guidelines for the Diagnosis and Management of Asthma (2007).  Maintenance ICS ranges are different for age 12+ yrs vs. younger asthmatics, but medium-dose ranges are easily satisfied with the included preparations, which include formoterol in combination with budesonide 160 mcg/actuation (0.16 mg/actuation) and formoterol in combination with mometasone 200 mcg/actuation (0.2 mg/actuation).),(Exclusion Criteria: Excludes withdrawn preparations and retired codes (although they may still be available from pharmacies until supplies are exhausted); excludes low-dose oral ICS-formoterol preparations that are less likely to be used to treat asthmatics age 4+ in the medium-dose ranges as per the NHLBI NAEPP EPR3 Guidelines for the Diagnosis and Management of Asthma (2007).)",
  "compose": {
    "include": [
      {
        "system": "http://www.nlm.nih.gov/research/umls/rxnorm",
        "concept": [
          {
            "code": "1246304",
            "display": "120 ACTUAT budesonide 0.16 MG/ACTUAT / formoterol fumarate 0.0045 MG/ACTUAT Metered Dose Inhaler"
          },
          {
            "code": "1246306",
            "display": "120 ACTUAT budesonide 0.16 MG/ACTUAT / formoterol fumarate 0.0045 MG/ACTUAT Metered Dose Inhaler [Symbicort]"
          },
          {
            "code": "1246311",
            "display": "120 ACTUAT formoterol fumarate 0.005 MG/ACTUAT / mometasone furoate 0.2 MG/ACTUAT Metered Dose Inhaler"
          },
          {
            "code": "1246313",
            "display": "120 ACTUAT formoterol fumarate 0.005 MG/ACTUAT / mometasone furoate 0.2 MG/ACTUAT Metered Dose Inhaler [Dulera]"
          },
          {
            "code": "1246316",
            "display": "60 ACTUAT budesonide 0.16 MG/ACTUAT / formoterol fumarate 0.0045 MG/ACTUAT Metered Dose Inhaler"
          },
          {
            "code": "1246317",
            "display": "60 ACTUAT budesonide 0.16 MG/ACTUAT / formoterol fumarate 0.0045 MG/ACTUAT Metered Dose Inhaler [Symbicort]"
          },
          {
            "code": "1660937",
            "display": "60 ACTUAT formoterol fumarate 0.005 MG/ACTUAT / mometasone furoate 0.2 MG/ACTUAT Metered Dose Inhaler"
          },
          {
            "code": "1660938",
            "display": "60 ACTUAT formoterol fumarate 0.005 MG/ACTUAT / mometasone furoate 0.2 MG/ACTUAT Metered Dose Inhaler [Dulera]"
          }
        ]
      }
    ]
  },
  "expansion": {
    "identifier": "urn:uuid:808fd908-4495-4ab4-af6e-5f8d2ab205cf",
    "timestamp": "2025-05-23T19:13:51-04:00",
    "total": 8,
    "contains": [
      {
        "system": "http://www.nlm.nih.gov/research/umls/rxnorm",
        "version": "05052025",
        "code": "1246304",
        "display": "120 ACTUAT budesonide 0.16 MG/ACTUAT / formoterol fumarate 0.0045 MG/ACTUAT Metered Dose Inhaler"
      },
      {
        "system": "http://www.nlm.nih.gov/research/umls/rxnorm",
        "version": "05052025",
        "code": "1246306",
        "display": "120 ACTUAT budesonide 0.16 MG/ACTUAT / formoterol fumarate 0.0045 MG/ACTUAT Metered Dose Inhaler [Symbicort]"
      },
      {
        "system": "http://www.nlm.nih.gov/research/umls/rxnorm",
        "version": "05052025",
        "code": "1246311",
        "display": "120 ACTUAT formoterol fumarate 0.005 MG/ACTUAT / mometasone furoate 0.2 MG/ACTUAT Metered Dose Inhaler"
      },
      {
        "system": "http://www.nlm.nih.gov/research/umls/rxnorm",
        "version": "05052025",
        "code": "1246313",
        "display": "120 ACTUAT formoterol fumarate 0.005 MG/ACTUAT / mometasone furoate 0.2 MG/ACTUAT Metered Dose Inhaler [Dulera]"
      },
      {
        "system": "http://www.nlm.nih.gov/research/umls/rxnorm",
        "version": "05052025",
        "code": "1246316",
        "display": "60 ACTUAT budesonide 0.16 MG/ACTUAT / formoterol fumarate 0.0045 MG/ACTUAT Metered Dose Inhaler"
      },
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        "system": "http://www.nlm.nih.gov/research/umls/rxnorm",
        "version": "05052025",
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        "display": "60 ACTUAT formoterol fumarate 0.005 MG/ACTUAT / mometasone furoate 0.2 MG/ACTUAT Metered Dose Inhaler"
      },
      {
        "system": "http://www.nlm.nih.gov/research/umls/rxnorm",
        "version": "05052025",
        "code": "1660938",
        "display": "60 ACTUAT formoterol fumarate 0.005 MG/ACTUAT / mometasone furoate 0.2 MG/ACTUAT Metered Dose Inhaler [Dulera]"
      }
    ]
  }
}