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Source1

{
  "resourceType": "ValueSet",
  "id": "2.16.840.1.113762.1.4.1196.393",
  "meta": {
    "versionId": "39",
    "lastUpdated": "2024-02-22T15:25:56.000-05:00",
    "profile": [
      "http://hl7.org/fhir/StructureDefinition/shareablevalueset",
      "http://hl7.org/fhir/us/cqfmeasures/StructureDefinition/computable-valueset-cqfm",
      "http://hl7.org/fhir/us/cqfmeasures/StructureDefinition/publishable-valueset-cqfm"
    ]
  },
  "extension": [
    {
      "url": "http://hl7.org/fhir/StructureDefinition/valueset-author",
      "valueContactDetail": {
        "name": "Mathematica PSI Author"
      }
    },
    {
      "url": "http://hl7.org/fhir/StructureDefinition/resource-lastReviewDate",
      "valueDate": "2025-02-05"
    },
    {
      "url": "http://hl7.org/fhir/StructureDefinition/valueset-effectiveDate",
      "valueDate": "2024-01-17"
    }
  ],
  "url": "http://cts.nlm.nih.gov/fhir/ValueSet/2.16.840.1.113762.1.4.1196.393",
  "identifier": [
    {
      "system": "urn:ietf:rfc:3986",
      "value": "urn:oid:2.16.840.1.113762.1.4.1196.393"
    }
  ],
  "version": "20240117",
  "name": "HypoglycemicsSevereHypoglycemia",
  "title": "Hypoglycemics Severe Hypoglycemia",
  "status": "active",
  "date": "2024-01-17T01:08:53-05:00",
  "publisher": "Mathematica PSI Steward",
  "jurisdiction": [
    {
      "coding": [
        {
          "system": "urn:iso:std:iso:3166",
          "code": "US"
        }
      ]
    }
  ],
  "purpose": "(Clinical Focus: The purpose of this value set is to represent concepts for medications capable of causing severe hypoglycemia.),(Data Element Scope: This value set may use a model element related to Medication.),(Inclusion Criteria: Includes concepts that represent insulin, non-insulin injectable antidiabetics, and oral antidiabetic medication.),(Exclusion Criteria: Excludes concepts that represent medications used to treat diabetes mellitus but are not commonly associated with severe hypoglycemia.)",
  "compose": {
    "include": [
      {
        "system": "http://www.nlm.nih.gov/research/umls/rxnorm",
        "concept": [
          {
            "code": "1361493",
            "display": "glimepiride 6 MG Oral Tablet"
          },
          {
            "code": "1361495",
            "display": "glimepiride 8 MG Oral Tablet"
          },
          {
            "code": "153842",
            "display": "glimepiride 3 MG Oral Tablet"
          },
          {
            "code": "1543202",
            "display": "insulin, regular, human 4 UNT Inhalation Powder"
          },
          {
            "code": "1544488",
            "display": "insulin, regular, human 8 UNT Inhalation Powder"
          },
          {
            "code": "1551295",
            "display": "0.5 ML dulaglutide 1.5 MG/ML Auto-Injector"
          },
          {
            "code": "1551304",
            "display": "0.5 ML dulaglutide 3 MG/ML Auto-Injector"
          },
          {
            "code": "1604539",
            "display": "1.5 ML insulin glargine 300 UNT/ML Pen Injector"
          },
          {
            "code": "1652239",
            "display": "3 ML insulin lispro 200 UNT/ML Pen Injector"
          },
          {
            "code": "1652639",
            "display": "3 ML insulin lispro 100 UNT/ML Pen Injector"
          },
          {
            "code": "1652644",
            "display": "3 ML insulin lispro 100 UNT/ML Cartridge"
          },
          {
            "code": "1653196",
            "display": "3 ML insulin aspart, human 100 UNT/ML Cartridge"
          },
          {
            "code": "1653202",
            "display": "3 ML insulin aspart, human 100 UNT/ML Pen Injector"
          },
          {
            "code": "1654862",
            "display": "3 ML insulin isophane, human 100 UNT/ML Pen Injector"
          },
          {
            "code": "1654910",
            "display": "insulin, regular, human 12 UNT Inhalation Powder"
          },
          {
            "code": "1670011",
            "display": "3 ML insulin degludec 100 UNT/ML Pen Injector"
          },
          {
            "code": "1670021",
            "display": "3 ML insulin degludec 200 UNT/ML Pen Injector"
          },
          {
            "code": "1731315",
            "display": "3 ML insulin, regular, human 500 UNT/ML Pen Injector"
          },
          {
            "code": "1798387",
            "display": "{90 (insulin, regular, human 4 UNT Inhalation Powder) / 90 (insulin, regular, human 8 UNT Inhalation Powder) } Pack"
          },
          {
            "code": "1860167",
            "display": "3 ML insulin degludec 100 UNT/ML / liraglutide 3.6 MG/ML Pen Injector"
          },
          {
            "code": "1862101",
            "display": "{60 (insulin, regular, human 12 UNT Inhalation Powder) / 60 (insulin, regular, human 4 UNT Inhalation Powder) / 60 (insulin, regular, human 8 UNT Inhalation Powder) } Pack"
          },
          {
            "code": "1926331",
            "display": "0.5 UNT Doses 3 ML insulin lispro 100 UNT/ML Pen Injector"
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          {
            "code": "197495",
            "display": "chlorpropamide 100 MG Oral Tablet"
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          {
            "code": "197496",
            "display": "chlorpropamide 250 MG Oral Tablet"
          },
          {
            "code": "197737",
            "display": "glyburide 1.25 MG Oral Tablet"
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          {
            "code": "198292",
            "display": "tolazamide 250 MG Oral Tablet"
          },
          {
            "code": "198293",
            "display": "tolazamide 500 MG Oral Tablet"
          },
          {
            "code": "198294",
            "display": "tolbutamide 500 MG Oral Tablet"
          },
          {
            "code": "199245",
            "display": "glimepiride 1 MG Oral Tablet"
          },
          {
            "code": "199246",
            "display": "glimepiride 2 MG Oral Tablet"
          },
          {
            "code": "199247",
            "display": "glimepiride 4 MG Oral Tablet"
          },
          {
            "code": "2002419",
            "display": "3 ML insulin glargine 300 UNT/ML Pen Injector"
          },
          {
            "code": "200256",
            "display": "repaglinide 1 MG Oral Tablet"
          },
          {
            "code": "200257",
            "display": "repaglinide 0.5 MG Oral Tablet"
          },
          {
            "code": "200258",
            "display": "repaglinide 2 MG Oral Tablet"
          },
          {
            "code": "2100028",
            "display": "{90 (insulin, regular, human 12 UNT Inhalation Powder) / 90 (insulin, regular, human 8 UNT Inhalation Powder) } Pack"
          },
          {
            "code": "2107520",
            "display": "insulin degludec 100 UNT/ML Injectable Solution"
          },
          {
            "code": "2179744",
            "display": "100 ML insulin, regular, human 1 UNT/ML Injection"
          },
          {
            "code": "2206090",
            "display": "3 ML insulin, regular, human 100 UNT/ML Pen Injector"
          },
          {
            "code": "2268064",
            "display": "Sensor 3 ML insulin glargine 100 UNT/ML Pen Injector"
          },
          {
            "code": "2380231",
            "display": "insulin lispro-aabc 100 UNT/ML Injectable Solution"
          },
          {
            "code": "2380254",
            "display": "3 ML insulin lispro-aabc 200 UNT/ML Pen Injector"
          },
          {
            "code": "2380259",
            "display": "3 ML insulin lispro-aabc 100 UNT/ML Pen Injector"
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          {
            "code": "2380267",
            "display": "Sensor 3 ML insulin lispro-aabc 100 UNT/ML Pen Injector"
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          {
            "code": "2395777",
            "display": "0.5 ML dulaglutide 6 MG/ML Auto-Injector"
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          {
            "code": "2395783",
            "display": "0.5 ML dulaglutide 9 MG/ML Auto-Injector"
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          {
            "code": "242120",
            "display": "insulin lispro 100 UNT/ML Injectable Solution"
          },
          {
            "code": "249220",
            "display": "insulin, regular, human 500 UNT/ML Injectable Solution"
          },
          {
            "code": "2563971",
            "display": "3 ML insulin glargine-yfgn 100 UNT/ML Pen Injector"
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          {
            "code": "2563976",
            "display": "insulin glargine-yfgn 100 UNT/ML Injectable Solution"
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          {
            "code": "2589008",
            "display": "3 ML insulin glargine-aglr 100 UNT/ML Pen Injector"
          },
          {
            "code": "259111",
            "display": "insulin lispro 25 UNT/ML / insulin lispro protamine, human 75 UNT/ML Injectable Suspension"
          },
          {
            "code": "260265",
            "display": "insulin lispro 50 UNT/ML / insulin lispro protamine, human 50 UNT/ML Injectable Suspension"
          },
          {
            "code": "2621571",
            "display": "Sensor 3 ML insulin lispro 100 UNT/ML Pen Injector"
          },
          {
            "code": "2642808",
            "display": "1.6 ML insulin aspart, human 100 UNT/ML Cartridge"
          },
          {
            "code": "2644768",
            "display": "{9 (insulin, regular, human 12 UNT Inhalation Powder) / 9 (insulin, regular, human 4 UNT Inhalation Powder) / 9 (insulin, regular, human 8 UNT Inhalation Powder) } Pack"
          },
          {
            "code": "310488",
            "display": "glipizide 10 MG Oral Tablet"
          },
          {
            "code": "310489",
            "display": "24 HR glipizide 2.5 MG Extended Release Oral Tablet"
          },
          {
            "code": "310490",
            "display": "glipizide 5 MG Oral Tablet"
          },
          {
            "code": "310534",
            "display": "glyburide 2.5 MG Oral Tablet"
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          {
            "code": "310536",
            "display": "glyburide 3 MG Oral Tablet"
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          {
            "code": "310537",
            "display": "glyburide 5 MG Oral Tablet"
          },
          {
            "code": "310539",
            "display": "glyburide 6 MG Oral Tablet"
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          {
            "code": "311028",
            "display": "insulin isophane, human 100 UNT/ML Injectable Suspension"
          },
          {
            "code": "311034",
            "display": "insulin, regular, human 100 UNT/ML Injectable Solution"
          },
          {
            "code": "311040",
            "display": "insulin aspart, human 100 UNT/ML Injectable Solution"
          },
          {
            "code": "311041",
            "display": "insulin glargine 100 UNT/ML Injectable Solution"
          },
          {
            "code": "311048",
            "display": "insulin isophane, human 70 UNT/ML / insulin, regular, human 30 UNT/ML Injectable Suspension"
          },
          {
            "code": "311919",
            "display": "nateglinide 120 MG Oral Tablet"
          },
          {
            "code": "314000",
            "display": "glyburide 1.5 MG Oral Tablet"
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          {
            "code": "314006",
            "display": "24 HR glipizide 5 MG Extended Release Oral Tablet"
          },
          {
            "code": "314142",
            "display": "nateglinide 60 MG Oral Tablet"
          },
          {
            "code": "315107",
            "display": "24 HR glipizide 10 MG Extended Release Oral Tablet"
          },
          {
            "code": "351297",
            "display": "insulin aspart protamine, human 70 UNT/ML / insulin aspart, human 30 UNT/ML Injectable Suspension"
          },
          {
            "code": "379804",
            "display": "glipizide 2.5 MG Oral Tablet"
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          {
            "code": "484322",
            "display": "insulin detemir 100 UNT/ML Injectable Solution"
          },
          {
            "code": "485210",
            "display": "insulin glulisine, human 100 UNT/ML Injectable Solution"
          },
          {
            "code": "647237",
            "display": "glimepiride 2 MG / pioglitazone 30 MG Oral Tablet"
          },
          {
            "code": "647239",
            "display": "glimepiride 4 MG / pioglitazone 30 MG Oral Tablet"
          },
          {
            "code": "847187",
            "display": "3 ML insulin isophane, human 70 UNT/ML / insulin, regular, human 30 UNT/ML Pen Injector"
          },
          {
            "code": "847191",
            "display": "3 ML insulin aspart protamine, human 70 UNT/ML / insulin aspart, human 30 UNT/ML Pen Injector"
          },
          {
            "code": "847211",
            "display": "3 ML insulin lispro 50 UNT/ML / insulin lispro protamine, human 50 UNT/ML Pen Injector"
          },
          {
            "code": "847230",
            "display": "3 ML insulin glargine 100 UNT/ML Pen Injector"
          },
          {
            "code": "847239",
            "display": "3 ML insulin detemir 100 UNT/ML Pen Injector"
          },
          {
            "code": "847252",
            "display": "3 ML insulin lispro 25 UNT/ML / insulin lispro protamine, human 75 UNT/ML Pen Injector"
          },
          {
            "code": "847259",
            "display": "3 ML insulin glulisine, human 100 UNT/ML Pen Injector"
          },
          {
            "code": "861731",
            "display": "glipizide 2.5 MG / metformin hydrochloride 250 MG Oral Tablet"
          },
          {
            "code": "861736",
            "display": "glipizide 2.5 MG / metformin hydrochloride 500 MG Oral Tablet"
          },
          {
            "code": "861740",
            "display": "glipizide 5 MG / metformin hydrochloride 500 MG Oral Tablet"
          },
          {
            "code": "861743",
            "display": "glyburide 1.25 MG / metformin hydrochloride 250 MG Oral Tablet"
          },
          {
            "code": "861748",
            "display": "glyburide 2.5 MG / metformin hydrochloride 500 MG Oral Tablet"
          },
          {
            "code": "861753",
            "display": "glyburide 5 MG / metformin hydrochloride 500 MG Oral Tablet"
          }
        ]
      }
    ]
  },
  "expansion": {
    "identifier": "urn:uuid:2932e9f7-2c0e-43c9-bcb8-2e0cc2811554",
    "timestamp": "2025-05-23T19:13:32-04:00",
    "total": 92,
    "contains": [
      {
        "system": "http://www.nlm.nih.gov/research/umls/rxnorm",
        "version": "05052025",
        "code": "1361493",
        "display": "glimepiride 6 MG Oral Tablet"
      },
      {
        "system": "http://www.nlm.nih.gov/research/umls/rxnorm",
        "version": "05052025",
        "code": "1361495",
        "display": "glimepiride 8 MG Oral Tablet"
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        "system": "http://www.nlm.nih.gov/research/umls/rxnorm",
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        "display": "glimepiride 3 MG Oral Tablet"
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        "system": "http://www.nlm.nih.gov/research/umls/rxnorm",
        "version": "05052025",
        "code": "1543202",
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      {
        "system": "http://www.nlm.nih.gov/research/umls/rxnorm",
        "version": "05052025",
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        "system": "http://www.nlm.nih.gov/research/umls/rxnorm",
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        "system": "http://www.nlm.nih.gov/research/umls/rxnorm",
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        "system": "http://www.nlm.nih.gov/research/umls/rxnorm",
        "version": "05052025",
        "code": "1604539",
        "display": "1.5 ML insulin glargine 300 UNT/ML Pen Injector"
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      {
        "system": "http://www.nlm.nih.gov/research/umls/rxnorm",
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        "code": "1652239",
        "display": "3 ML insulin lispro 200 UNT/ML Pen Injector"
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        "system": "http://www.nlm.nih.gov/research/umls/rxnorm",
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        "display": "3 ML insulin lispro 100 UNT/ML Pen Injector"
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        "system": "http://www.nlm.nih.gov/research/umls/rxnorm",
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        "system": "http://www.nlm.nih.gov/research/umls/rxnorm",
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      },
      {
        "system": "http://www.nlm.nih.gov/research/umls/rxnorm",
        "version": "05052025",
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        "display": "0.5 UNT Doses 3 ML insulin lispro 100 UNT/ML Pen Injector"
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      {
        "system": "http://www.nlm.nih.gov/research/umls/rxnorm",
        "version": "05052025",
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        "display": "chlorpropamide 100 MG Oral Tablet"
      },
      {
        "system": "http://www.nlm.nih.gov/research/umls/rxnorm",
        "version": "05052025",
        "code": "197496",
        "display": "chlorpropamide 250 MG Oral Tablet"
      },
      {
        "system": "http://www.nlm.nih.gov/research/umls/rxnorm",
        "version": "05052025",
        "code": "197737",
        "display": "glyburide 1.25 MG Oral Tablet"
      },
      {
        "system": "http://www.nlm.nih.gov/research/umls/rxnorm",
        "version": "05052025",
        "code": "198292",
        "display": "tolazamide 250 MG Oral Tablet"
      },
      {
        "system": "http://www.nlm.nih.gov/research/umls/rxnorm",
        "version": "05052025",
        "code": "198293",
        "display": "tolazamide 500 MG Oral Tablet"
      },
      {
        "system": "http://www.nlm.nih.gov/research/umls/rxnorm",
        "version": "05052025",
        "code": "198294",
        "display": "tolbutamide 500 MG Oral Tablet"
      },
      {
        "system": "http://www.nlm.nih.gov/research/umls/rxnorm",
        "version": "05052025",
        "code": "199245",
        "display": "glimepiride 1 MG Oral Tablet"
      },
      {
        "system": "http://www.nlm.nih.gov/research/umls/rxnorm",
        "version": "05052025",
        "code": "199246",
        "display": "glimepiride 2 MG Oral Tablet"
      },
      {
        "system": "http://www.nlm.nih.gov/research/umls/rxnorm",
        "version": "05052025",
        "code": "199247",
        "display": "glimepiride 4 MG Oral Tablet"
      },
      {
        "system": "http://www.nlm.nih.gov/research/umls/rxnorm",
        "version": "05052025",
        "code": "2002419",
        "display": "3 ML insulin glargine 300 UNT/ML Pen Injector"
      },
      {
        "system": "http://www.nlm.nih.gov/research/umls/rxnorm",
        "version": "05052025",
        "code": "200256",
        "display": "repaglinide 1 MG Oral Tablet"
      },
      {
        "system": "http://www.nlm.nih.gov/research/umls/rxnorm",
        "version": "05052025",
        "code": "200257",
        "display": "repaglinide 0.5 MG Oral Tablet"
      },
      {
        "system": "http://www.nlm.nih.gov/research/umls/rxnorm",
        "version": "05052025",
        "code": "200258",
        "display": "repaglinide 2 MG Oral Tablet"
      },
      {
        "system": "http://www.nlm.nih.gov/research/umls/rxnorm",
        "version": "05052025",
        "code": "2100028",
        "display": "{90 (insulin, regular, human 12 UNT Inhalation Powder) / 90 (insulin, regular, human 8 UNT Inhalation Powder) } Pack"
      },
      {
        "system": "http://www.nlm.nih.gov/research/umls/rxnorm",
        "version": "05052025",
        "code": "2107520",
        "display": "insulin degludec 100 UNT/ML Injectable Solution"
      },
      {
        "system": "http://www.nlm.nih.gov/research/umls/rxnorm",
        "version": "05052025",
        "code": "2179744",
        "display": "100 ML insulin, regular, human 1 UNT/ML Injection"
      },
      {
        "system": "http://www.nlm.nih.gov/research/umls/rxnorm",
        "version": "05052025",
        "code": "2206090",
        "display": "3 ML insulin, regular, human 100 UNT/ML Pen Injector"
      },
      {
        "system": "http://www.nlm.nih.gov/research/umls/rxnorm",
        "version": "05052025",
        "code": "2268064",
        "display": "Sensor 3 ML insulin glargine 100 UNT/ML Pen Injector"
      },
      {
        "system": "http://www.nlm.nih.gov/research/umls/rxnorm",
        "version": "05052025",
        "code": "2380231",
        "display": "insulin lispro-aabc 100 UNT/ML Injectable Solution"
      },
      {
        "system": "http://www.nlm.nih.gov/research/umls/rxnorm",
        "version": "05052025",
        "code": "2380254",
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