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Packagenictiz.fhir.nl.r4.medicationprocess9
Resource TypeStructureDefinition
Idmp-InstructionsForUse.DosageInstructions.json
FHIR VersionR4
Sourcehttps://simplifier.net/resolve?scope=nictiz.fhir.nl.r4.medicationprocess9@2.0.0-rc.7&canonical=http://nictiz.nl/fhir/StructureDefinition/mp-InstructionsForUse.DosageInstructions
URLhttp://nictiz.nl/fhir/StructureDefinition/mp-InstructionsForUse.DosageInstructions
Version2.0.0-rc.7
Statusactive
NameMpInstructionsForUseDosageInstructions
Titlemp InstructionsForUse.DosageInstructions
Realmnl
DescriptionInstructions for the use or administration of the medication, e.g. dose and route of administration. In the medication building block MedicationUse, this is the pattern of use established by the patient or which the patient followed.
PurposeThis Dosage data type profile _mainly_ represents the DosingInstructions concept of the sub building block InstructionsForUse, for implementations following the information standard [MP9](https://informatiestandaarden.nictiz.nl/wiki/Landingspagina_Medicatieproces). This profile is based on the Dutch zib ('Zorginformatiebouwsteen', i.e. Health and Care Information Model) InstructionsForUse, but has no dependency on the corresponding nl-core profile because it contains non-compatible changes. Where compatible, mappings to zib concepts are defined. Additional concepts or concepts that are not compatible with their zib counterparts contain a mapping to the MP9 data set. This profile also includes the concepts AdditionalInstructions and RouteOfAdministration. These concepts are placed on the same level as DosingInstructions in the zib, but are in FHIR part of the Dosage data type. As a consequence, these concepts may be duplicated if this Dosage profile is instantiated multiple times. This profile should be used in medication related resources that define dosage instructions and supplemented by the extensions [ext-RenderedDosageInstruction](http://nictiz.nl/fhir/StructureDefinition/ext-RenderedDosageInstruction) and [ext-InstructionsForUse.RepeatPeriodCyclicalSchedule](http://nictiz.nl/fhir/StructureDefinition/ext-InstructionsForUse.RepeatPeriodCyclicalSchedule) to implement the remaining concepts Description and RepeatPeriodCyclicalSchedule.
CopyrightCopyright and related rights waived via CC0, https://creativecommons.org/publicdomain/zero/1.0/. This does not apply to information from third parties, for example a medical terminology system. The implementer alone is responsible for identifying and obtaining any necessary licenses or authorizations to utilize third party IP in connection with the specification or otherwise.
TypeDosage
Kindcomplex-type

Resources that use this resource

StructureDefinition
nictiz.fhir.nl.r4.medicationprocess9#2.0.0-rc.7mp-AdministrationAgreementmp AdministrationAgreement
nictiz.fhir.nl.r4.medicationprocess9#2.0.0-rc.7mp-MedicationAgreementmp MedicationAgreement
nictiz.fhir.nl.r4.medicationprocess9#2.0.0-rc.7mp-MedicationUse2mp MedicationUse2
nictiz.fhir.nl.r4.medicationprocess9#2.0.0-rc.7mp-VariableDosingRegimenmp VariableDosingRegimen

Resources that this resource uses

StructureDefinition
nictiz.fhir.nl.r4.medicationprocess9#2.0.0-rc.7ext-Dosage-AsNeededForext Dosage AsNeededFor
nictiz.fhir.nl.r4.zib2020#0.12.0-labtrial.1pattern-GstdSimpleQuantityG-Standard SimpleQuantity
ValueSet
nictiz.fhir.nl.r4.medicationprocess9#2.0.0-rc.72.16.840.1.113883.2.4.3.11.60.20.77.11.9--20160407000000Aanvullende gebruiksinstructie
nictiz.fhir.nl.r4.medicationprocess9#2.0.0-rc.72.16.840.1.113883.2.4.3.11.60.40.2.9.12.1--20200901000000MedicatieToedieningswegCodelijst
nictiz.fhir.nl.r4.medicationprocess9#2.0.0-rc.72.16.840.1.113883.2.4.3.11.60.40.2.9.12.4--20200901000000ZonodigCriteriumCodelijst

Narrative

No narrative content found in resource


Source1

{
  "resourceType": "StructureDefinition",
  "id": "mp-InstructionsForUse.DosageInstructions",
  "url": "http://nictiz.nl/fhir/StructureDefinition/mp-InstructionsForUse.DosageInstructions",
  "version": "2.0.0-rc.7",
  "name": "MpInstructionsForUseDosageInstructions",
  "title": "mp InstructionsForUse.DosageInstructions",
  "status": "active",
  "publisher": "Nictiz",
  "contact": [
    {
      "name": "Nictiz",
      "telecom": [
        {
          "system": "url",
          "value": "https://www.nictiz.nl",
          "use": "work"
        }
      ]
    }
  ],
  "description": "Instructions for the use or administration of the medication, e.g. dose and route of administration. In the medication building block MedicationUse, this is the pattern of use established by the patient or which the patient followed.",
  "purpose": "This Dosage data type profile _mainly_ represents the DosingInstructions concept of the sub building block InstructionsForUse, for implementations following the information standard [MP9](https://informatiestandaarden.nictiz.nl/wiki/Landingspagina_Medicatieproces). This profile is based on the Dutch zib ('Zorginformatiebouwsteen', i.e. Health and Care Information Model) InstructionsForUse, but has no dependency on the corresponding nl-core profile because it contains non-compatible changes. Where compatible, mappings to zib concepts are defined. Additional concepts or concepts that are not compatible with their zib counterparts contain a mapping to the MP9 data set.\n\nThis profile also includes the concepts AdditionalInstructions and RouteOfAdministration. These concepts are placed on the same level as DosingInstructions in the zib, but are in FHIR part of the Dosage data type. As a consequence, these concepts may be duplicated if this Dosage profile is instantiated multiple times.\n\nThis profile should be used in medication related resources that define dosage instructions and supplemented by the extensions [ext-RenderedDosageInstruction](http://nictiz.nl/fhir/StructureDefinition/ext-RenderedDosageInstruction) and [ext-InstructionsForUse.RepeatPeriodCyclicalSchedule](http://nictiz.nl/fhir/StructureDefinition/ext-InstructionsForUse.RepeatPeriodCyclicalSchedule) to implement the remaining concepts Description and RepeatPeriodCyclicalSchedule.",
  "copyright": "Copyright and related rights waived via CC0, https://creativecommons.org/publicdomain/zero/1.0/. This does not apply to information from third parties, for example a medical terminology system. The implementer alone is responsible for identifying and obtaining any necessary licenses or authorizations to utilize third party IP in connection with the specification or otherwise.",
  "fhirVersion": "4.0.1",
  "mapping": [
    {
      "identity": "zib-instructionsforuse-v1.2.1-2020EN",
      "uri": "https://zibs.nl/wiki/InstructionsForUse-v1.2.1(2020EN)",
      "name": "zib InstructionsForUse-v1.2.1(2020EN)"
    },
    {
      "identity": "zib-range-v1.0.1-2020EN",
      "uri": "https://zibs.nl/wiki/Range-v1.0.1(2020EN)",
      "name": "zib Range-v1.0.1(2020EN)"
    },
    {
      "identity": "mp-dataset-mp9-300-rc1-20250522",
      "uri": "https://decor.nictiz.nl/pub/medicatieproces/mp-html-20250522T132618/ds-2.16.840.1.113883.2.4.3.11.60.20.77.1.4-2022-06-30T000000.html",
      "name": "ART-DECOR Dataset MP9 3.0.0-rc.1 20250522"
    },
    {
      "identity": "mp-dataset-mp9-300-rc2-20260213",
      "uri": "https://decor.nictiz.nl/pub/medicatieproces/mp-html-20260213T112547/ds-2.16.840.1.113883.2.4.3.11.60.20.77.1.4-2022-06-30T000000.html",
      "name": "ART-DECOR Dataset MP9 3.0.0-rc.2 20260213"
    }
  ],
  "kind": "complex-type",
  "abstract": false,
  "type": "Dosage",
  "baseDefinition": "http://hl7.org/fhir/StructureDefinition/Dosage",
  "derivation": "constraint",
  "snapshot": {
    "element": [
      {
        "id": "Dosage",
        "path": "Dosage",
        "short": "DosingInstructions",
        "definition": "Indicates how the medication is/was taken or should be taken by the patient. Instructions for the administrator to administer the medication (the patient themselves, a nurse or other aid). When taking stock of medication use, the dosage describes the pattern of use established by the patient.",
        "comment": "This element _mostly_ represents the DosingInstructions container from zib InstructionsForUse, but also includes the AdditionalInstructions and RouteOfAdministration concepts, which are normally placed on the same level as this container. As a result, these concepts are **duplicated** in every repetition of this element, even though these concepts should be present just once according to the zib.\r\n\r\nThis element does not contain a mapping to the Dosage container from zib InstructionsForUse. However, all child concepts of the Dosage concept are mapped. If an instance of zib container DosingInstructions contains multiple Dosage containers, each of these results in a separate instance of the FHIR Dosage data type conforming to this profile, wherein `.sequence` (zib concept SequenceNumber) and `.timing.repeat.bounds[x]:boundsDuration` (zib concept DoseDuration) are equal.",
        "alias": [
          "Doseerinstructie"
        ],
        "min": 0,
        "max": "*",
        "base": {
          "path": "Dosage",
          "min": 0,
          "max": "*"
        },
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          }
        ],
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "rim",
            "map": ".outboundRelationship[typeCode=COMP].target[classCode=SBADM, moodCode=INT]"
          },
          {
            "identity": "zib-instructionsforuse-v1.2.1-2020EN",
            "map": "NL-CM:9.12.22095",
            "comment": "DosingInstructions"
          }
        ]
      },
      {
        "id": "Dosage.id",
        "path": "Dosage.id",
        "representation": [
          "xmlAttr"
        ],
        "short": "Unique id for inter-element referencing",
        "definition": "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Element.id",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
                "valueUrl": "string"
              }
            ],
            "code": "http://hl7.org/fhirpath/System.String"
          }
        ],
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          }
        ]
      },
      {
        "id": "Dosage.extension",
        "path": "Dosage.extension",
        "slicing": {
          "discriminator": [
            {
              "type": "value",
              "path": "url"
            }
          ],
          "description": "Extensions are always sliced by (at least) url",
          "rules": "open"
        },
        "short": "Additional content defined by implementations",
        "definition": "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance  applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.",
        "comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
        "alias": [
          "extensions",
          "user content"
        ],
        "min": 0,
        "max": "*",
        "base": {
          "path": "Element.extension",
          "min": 0,
          "max": "*"
        },
        "type": [
          {
            "code": "Extension"
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          },
          {
            "key": "ext-1",
            "severity": "error",
            "human": "Must have either extensions or value[x], not both",
            "expression": "extension.exists() != value.exists()",
            "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), 'value')])",
            "source": "http://hl7.org/fhir/StructureDefinition/Extension"
          }
        ],
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "rim",
            "map": "N/A"
          }
        ]
      },
      {
        "id": "Dosage.extension:asNeeded",
        "path": "Dosage.extension",
        "sliceName": "asNeeded",
        "short": "Optional Extensions Element",
        "definition": "Pre-adopt from FHIR R5 of the `Dosage.asNeededFor` element.",
        "comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
        "alias": [
          "extensions",
          "user content"
        ],
        "min": 0,
        "max": "*",
        "base": {
          "path": "Element.extension",
          "min": 0,
          "max": "*"
        },
        "type": [
          {
            "code": "Extension",
            "profile": [
              "http://nictiz.nl/fhir/StructureDefinition/ext-Dosage-AsNeededFor"
            ]
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          },
          {
            "key": "ext-1",
            "severity": "error",
            "human": "Must have either extensions or value[x], not both",
            "expression": "extension.exists() != value.exists()",
            "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), 'value')])",
            "source": "http://hl7.org/fhir/StructureDefinition/Extension"
          }
        ],
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "rim",
            "map": "N/A"
          }
        ]
      },
      {
        "id": "Dosage.extension:asNeeded.id",
        "path": "Dosage.extension.id",
        "representation": [
          "xmlAttr"
        ],
        "short": "Unique id for inter-element referencing",
        "definition": "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Element.id",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
                "valueUrl": "string"
              }
            ],
            "code": "http://hl7.org/fhirpath/System.String"
          }
        ],
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          }
        ]
      },
      {
        "id": "Dosage.extension:asNeeded.extension",
        "path": "Dosage.extension.extension",
        "slicing": {
          "discriminator": [
            {
              "type": "value",
              "path": "url"
            }
          ],
          "description": "Extensions are always sliced by (at least) url",
          "rules": "open"
        },
        "short": "Additional content defined by implementations",
        "definition": "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance  applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.",
        "comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
        "alias": [
          "extensions",
          "user content"
        ],
        "min": 0,
        "max": "*",
        "base": {
          "path": "Element.extension",
          "min": 0,
          "max": "*"
        },
        "type": [
          {
            "code": "Extension"
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          },
          {
            "key": "ext-1",
            "severity": "error",
            "human": "Must have either extensions or value[x], not both",
            "expression": "extension.exists() != value.exists()",
            "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), 'value')])",
            "source": "http://hl7.org/fhir/StructureDefinition/Extension"
          }
        ],
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "rim",
            "map": "N/A"
          }
        ]
      },
      {
        "id": "Dosage.extension:asNeeded.url",
        "path": "Dosage.extension.url",
        "representation": [
          "xmlAttr"
        ],
        "short": "identifies the meaning of the extension",
        "definition": "Source of the definition for the extension code - a logical name or a URL.",
        "comment": "The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.",
        "min": 1,
        "max": "1",
        "base": {
          "path": "Extension.url",
          "min": 1,
          "max": "1"
        },
        "type": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
                "valueUrl": "uri"
              }
            ],
            "code": "http://hl7.org/fhirpath/System.String"
          }
        ],
        "fixedUri": "http://nictiz.nl/fhir/StructureDefinition/ext-Dosage-AsNeededFor",
        "mapping": [
          {
            "identity": "rim",
            "map": "N/A"
          }
        ]
      },
      {
        "id": "Dosage.extension:asNeeded.value[x]",
        "path": "Dosage.extension.value[x]",
        "short": "Condition",
        "definition": "The condition for administering medication can be:\r\n\r\n* a physiological measurement value (plasma glucose concentration, body temperature, blood pressure);\r\n* a symptom or other circumstance (in the event of a headache, or itch).\r\n\r\nSupplemental information from G-standard bst362 make up the list of values for coded entering of this concept. Also always include the textual description of that code. Physiological measurement values or other conditions that do not occur in bst362 do not need to be coded. These can be expressed in free text in the Description concept.",
        "comment": "If only one 'asNeeded' concept is exchanged within a Dosage, use `Dosage.asNeeded[x]`. This extension is only used when multiple 'asNeeded' concepts are to be exchanged.",
        "alias": [
          "Criterium"
        ],
        "min": 0,
        "max": "1",
        "base": {
          "path": "Extension.value[x]",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "CodeableConcept"
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          }
        ],
        "binding": {
          "strength": "required",
          "valueSet": "http://decor.nictiz.nl/fhir/ValueSet/2.16.840.1.113883.2.4.3.11.60.40.2.9.12.4--20200901000000"
        },
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "rim",
            "map": "N/A"
          },
          {
            "identity": "zib-instructionsforuse-v1.2.1-2020EN",
            "map": "NL-CM:9.12.19945",
            "comment": "Condition"
          }
        ]
      },
      {
        "id": "Dosage.modifierExtension",
        "path": "Dosage.modifierExtension",
        "short": "Extensions that cannot be ignored even if unrecognized",
        "definition": "May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.\n\nModifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).",
        "comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
        "requirements": "Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored.  This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](extensibility.html#modifierExtension).",
        "alias": [
          "extensions",
          "user content",
          "modifiers"
        ],
        "min": 0,
        "max": "*",
        "base": {
          "path": "BackboneElement.modifierExtension",
          "min": 0,
          "max": "*"
        },
        "type": [
          {
            "code": "Extension"
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          },
          {
            "key": "ext-1",
            "severity": "error",
            "human": "Must have either extensions or value[x], not both",
            "expression": "extension.exists() != value.exists()",
            "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), 'value')])",
            "source": "http://hl7.org/fhir/StructureDefinition/Extension"
          }
        ],
        "isModifier": true,
        "isModifierReason": "Modifier extensions are expected to modify the meaning or interpretation of the element that contains them",
        "isSummary": true,
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "rim",
            "map": "N/A"
          }
        ]
      },
      {
        "id": "Dosage.sequence",
        "path": "Dosage.sequence",
        "short": "SequenceNumber",
        "definition": "This indicates the sequence of the dosing instructions within the medication agreement.",
        "comment": "32 bit number; for values larger than this, use decimal",
        "requirements": "If the sequence number of multiple Dosages is the same, then it is implied that the instructions are to be treated as concurrent.  If the sequence number is different, then the Dosages are intended to be sequential.",
        "alias": [
          "Volgnummer"
        ],
        "min": 0,
        "max": "1",
        "base": {
          "path": "Dosage.sequence",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "integer"
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          }
        ],
        "isSummary": true,
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "v2",
            "map": "TQ1-1"
          },
          {
            "identity": "rim",
            "map": ".text"
          },
          {
            "identity": "zib-instructionsforuse-v1.2.1-2020EN",
            "map": "NL-CM:9.12.22503",
            "comment": "SequenceNumber"
          }
        ]
      },
      {
        "id": "Dosage.text",
        "path": "Dosage.text",
        "short": "Free text dosage instructions e.g. SIG",
        "definition": "Free text dosage instructions e.g. SIG.",
        "comment": "Note that FHIR strings SHALL NOT exceed 1MB in size",
        "requirements": "Free text dosage instructions can be used for cases where the instructions are too complex to code.  The content of this attribute does not include the name or description of the medication. When coded instructions are present, the free text instructions may still be present for display to humans taking or administering the medication. It is expected that the text instructions will always be populated.  If the dosage.timing attribute is also populated, then the dosage.text should reflect the same information as the timing.  Additional information about administration or preparation of the medication should be included as text.",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Dosage.text",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "string"
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          }
        ],
        "isSummary": true,
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "v2",
            "map": "RXO-6; RXE-21"
          },
          {
            "identity": "rim",
            "map": ".text"
          }
        ]
      },
      {
        "id": "Dosage.additionalInstruction",
        "path": "Dosage.additionalInstruction",
        "short": "AdditionalInstructions",
        "definition": "The additional instructions contain extra information on the use of the current prescription. The additional instructions applies to the entire instructions for use and not to an individual dosage.\r\n\r\nThis includes all instructions for use. The text can come from the original “paper\" medication prescription, but can also be generated from the coded information.\r\n\r\nThe instructions may not conflict with other components of the medication agreement/ administration agreement.\r\n\r\nThe instructions can also refer to an existing protocol. In the case of an external dosing regimen (e.g., \"according to thrombosis service regimen\"), OTH is used.\r\n\r\nThe texts in the G-standard that can support this attribute are included in table 362 where the texts from the general practitioner' standard 'NHG-Tabel 25-component b: 'aanvullende teksten’ ' are included. These texts can only be used when it is not possible to include this information in the other structured elements of the Instructions for Use.\r\n\r\nA free-text explanation of the Instructions for Use can be placed under code OTH if it is not possible to record it in a structured manner within the Instructions for Use.",
        "comment": "Please note that in contrast to the zib, this AdditionalInstructions concept is grouped under the DosingInstructions concept. This `.additionalInstruction` element shall have the same value when there are multiple DosingInstructions.",
        "requirements": "Additional instruction is intended to be coded, but where no code exists, the element could include text.  For example, \"Swallow with plenty of water\" which might or might not be coded.",
        "alias": [
          "AanvullendeInstructie"
        ],
        "min": 0,
        "max": "*",
        "base": {
          "path": "Dosage.additionalInstruction",
          "min": 0,
          "max": "*"
        },
        "type": [
          {
            "code": "CodeableConcept"
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          }
        ],
        "isSummary": true,
        "binding": {
          "extension": [
            {
              "url": "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName",
              "valueString": "AdditionalInstruction"
            }
          ],
          "strength": "required",
          "description": "WCIAv3 Tabel 25 B-codes subset voor aanvullende gebruiksinstructies",
          "valueSet": "http://decor.nictiz.nl/fhir/ValueSet/2.16.840.1.113883.2.4.3.11.60.20.77.11.9--20160407000000"
        },
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "v2",
            "map": "CE/CNE/CWE"
          },
          {
            "identity": "rim",
            "map": "CD"
          },
          {
            "identity": "orim",
            "map": "fhir:CodeableConcept rdfs:subClassOf dt:CD"
          },
          {
            "identity": "v2",
            "map": "RXO-7"
          },
          {
            "identity": "rim",
            "map": ".text"
          },
          {
            "identity": "mp-dataset-mp9-300-rc1-20250522",
            "map": "mp-dataelement9x-51",
            "comment": "AdditionalInstructions"
          },
          {
            "identity": "mp-dataset-mp9-300-rc2-20260213",
            "map": "mp-dataelement9x-51",
            "comment": "AdditionalInstructions"
          },
          {
            "identity": "mp-dataset-mp9-300-rc1-20250522",
            "map": "mp-dataelement9x-649",
            "comment": "AdditionalInstructions"
          },
          {
            "identity": "mp-dataset-mp9-300-rc2-20260213",
            "map": "mp-dataelement9x-649",
            "comment": "AdditionalInstructions"
          },
          {
            "identity": "mp-dataset-mp9-300-rc1-20250522",
            "map": "mp-dataelement9x-300",
            "comment": "AdditionalInstructions"
          },
          {
            "identity": "mp-dataset-mp9-300-rc2-20260213",
            "map": "mp-dataelement9x-300",
            "comment": "AdditionalInstructions"
          },
          {
            "identity": "mp-dataset-mp9-300-rc1-20250522",
            "map": "mp-dataelement9x-368",
            "comment": "AdditionalInstructions"
          },
          {
            "identity": "mp-dataset-mp9-300-rc2-20260213",
            "map": "mp-dataelement9x-368",
            "comment": "AdditionalInstructions"
          }
        ]
      },
      {
        "id": "Dosage.patientInstruction",
        "path": "Dosage.patientInstruction",
        "short": "Patient or consumer oriented instructions",
        "definition": "Instructions in terms that are understood by the patient or consumer.",
        "comment": "Note that FHIR strings SHALL NOT exceed 1MB in size",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Dosage.patientInstruction",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "string"
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          }
        ],
        "isSummary": true,
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "v2",
            "map": "RXO-7"
          },
          {
            "identity": "rim",
            "map": ".text"
          }
        ]
      },
      {
        "id": "Dosage.timing",
        "path": "Dosage.timing",
        "short": "AdministeringSchedule",
        "definition": "Specifications of the times at which the medication is to be administered. This is indicated as follows:\r\n* Time(s) (16:00) or indications (“before meals”) at which the medication is to be taken each day.\r\n* A specific number of times the medication is to be taken each day (\"3x a day\"), indicated with the frequency.\r\n* A time interval between consecutive doses (“Every 2 hours”, “every 3 days”), indicated with the word Interval.\r\n* Combined periods with an interval and duration (“1 daily for three out of four weeks: the pill schedule”)\r\n\r\nIf a certain medication is not to be taken daily, the aforementioned can be combined with daily indications:\r\n\r\n* One or more week days on which the medication is to be administered (e.g. “Monday, Wednesday, Friday”)\r\n* ”3x a week”, “2x a month”.\r\n\r\nThe specified administration “infinite” is automatically to be repeated until:\r\n* The end date and time has been reached\r\n* The total administration duration has been reached (14 days)\r\n* A specific amount of administrations has been reached (“20 doses”), to be entered in the Frequency concept.",
        "comment": "This attribute might not always be populated while the Dosage.text is expected to be populated.  If both are populated, then the Dosage.text should reflect the content of the Dosage.timing.",
        "requirements": "The timing schedule for giving the medication to the patient. This  data type allows many different expressions. For example: \"Every 8 hours\"; \"Three times a day\"; \"1/2 an hour before breakfast for 10 days from 23-Dec 2011:\"; \"15 Oct 2013, 17 Oct 2013 and 1 Nov 2013\".  Sometimes, a rate can imply duration when expressed as total volume / duration (e.g.  500mL/2 hours implies a duration of 2 hours).  However, when rate doesn't imply duration (e.g. 250mL/hour), then the timing.repeat.duration is needed to convey the infuse over time period.",
        "alias": [
          "Toedieningsschema"
        ],
        "min": 0,
        "max": "1",
        "base": {
          "path": "Dosage.timing",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "Timing"
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          }
        ],
        "isSummary": true,
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "v2",
            "map": "N/A"
          },
          {
            "identity": "rim",
            "map": "QSET<TS> (GTS)"
          },
          {
            "identity": "rim",
            "map": ".effectiveTime"
          },
          {
            "identity": "zib-instructionsforuse-v1.2.1-2020EN",
            "map": "NL-CM:9.12.19948",
            "comment": "AdministeringSchedule"
          }
        ]
      },
      {
        "id": "Dosage.timing.id",
        "path": "Dosage.timing.id",
        "representation": [
          "xmlAttr"
        ],
        "short": "Unique id for inter-element referencing",
        "definition": "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Element.id",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
                "valueUrl": "string"
              }
            ],
            "code": "http://hl7.org/fhirpath/System.String"
          }
        ],
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          }
        ]
      },
      {
        "id": "Dosage.timing.extension",
        "path": "Dosage.timing.extension",
        "slicing": {
          "discriminator": [
            {
              "type": "value",
              "path": "url"
            }
          ],
          "description": "Extensions are always sliced by (at least) url",
          "rules": "open"
        },
        "short": "Additional content defined by implementations",
        "definition": "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance  applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.",
        "comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
        "alias": [
          "extensions",
          "user content"
        ],
        "min": 0,
        "max": "*",
        "base": {
          "path": "Element.extension",
          "min": 0,
          "max": "*"
        },
        "type": [
          {
            "code": "Extension"
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          },
          {
            "key": "ext-1",
            "severity": "error",
            "human": "Must have either extensions or value[x], not both",
            "expression": "extension.exists() != value.exists()",
            "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), 'value')])",
            "source": "http://hl7.org/fhir/StructureDefinition/Extension"
          }
        ],
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "rim",
            "map": "N/A"
          }
        ]
      },
      {
        "id": "Dosage.timing.modifierExtension",
        "path": "Dosage.timing.modifierExtension",
        "short": "Extensions that cannot be ignored even if unrecognized",
        "definition": "May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.\n\nModifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).",
        "comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
        "requirements": "Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored.  This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](extensibility.html#modifierExtension).",
        "alias": [
          "extensions",
          "user content",
          "modifiers"
        ],
        "min": 0,
        "max": "*",
        "base": {
          "path": "BackboneElement.modifierExtension",
          "min": 0,
          "max": "*"
        },
        "type": [
          {
            "code": "Extension"
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          },
          {
            "key": "ext-1",
            "severity": "error",
            "human": "Must have either extensions or value[x], not both",
            "expression": "extension.exists() != value.exists()",
            "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), 'value')])",
            "source": "http://hl7.org/fhir/StructureDefinition/Extension"
          }
        ],
        "isModifier": true,
        "isModifierReason": "Modifier extensions are expected to modify the meaning or interpretation of the element that contains them",
        "isSummary": true,
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "rim",
            "map": "N/A"
          }
        ]
      },
      {
        "id": "Dosage.timing.event",
        "path": "Dosage.timing.event",
        "short": "When the event occurs",
        "definition": "Identifies specific times when the event occurs.",
        "requirements": "In a Medication Administration Record, for instance, you need to take a general specification, and turn it into a precise specification.",
        "min": 0,
        "max": "*",
        "base": {
          "path": "Timing.event",
          "min": 0,
          "max": "*"
        },
        "type": [
          {
            "code": "dateTime"
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          }
        ],
        "isSummary": true,
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "rim",
            "map": "QLIST<TS>"
          }
        ]
      },
      {
        "id": "Dosage.timing.repeat",
        "path": "Dosage.timing.repeat",
        "short": "When the event is to occur",
        "definition": "A set of rules that describe when the event is scheduled.",
        "requirements": "Many timing schedules are determined by regular repetitions.",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Timing.repeat",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "Element"
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          },
          {
            "key": "tim-9",
            "severity": "error",
            "human": "If there's an offset, there must be a when (and not C, CM, CD, CV)",
            "expression": "offset.empty() or (when.exists() and ((when in ('C' | 'CM' | 'CD' | 'CV')).not()))",
            "xpath": "not(exists(f:offset)) or exists(f:when)",
            "source": "http://hl7.org/fhir/StructureDefinition/Timing"
          },
          {
            "key": "tim-5",
            "severity": "error",
            "human": "period SHALL be a non-negative value",
            "expression": "period.exists() implies period >= 0",
            "xpath": "f:period/@value >= 0 or not(f:period/@value)",
            "source": "http://hl7.org/fhir/StructureDefinition/Timing"
          },
          {
            "key": "tim-6",
            "severity": "error",
            "human": "If there's a periodMax, there must be a period",
            "expression": "periodMax.empty() or period.exists()",
            "xpath": "not(exists(f:periodMax)) or exists(f:period)",
            "source": "http://hl7.org/fhir/StructureDefinition/Timing"
          },
          {
            "key": "tim-7",
            "severity": "error",
            "human": "If there's a durationMax, there must be a duration",
            "expression": "durationMax.empty() or duration.exists()",
            "xpath": "not(exists(f:durationMax)) or exists(f:duration)",
            "source": "http://hl7.org/fhir/StructureDefinition/Timing"
          },
          {
            "key": "tim-8",
            "severity": "error",
            "human": "If there's a countMax, there must be a count",
            "expression": "countMax.empty() or count.exists()",
            "xpath": "not(exists(f:countMax)) or exists(f:count)",
            "source": "http://hl7.org/fhir/StructureDefinition/Timing"
          },
          {
            "key": "tim-1",
            "severity": "error",
            "human": "if there's a duration, there needs to be duration units",
            "expression": "duration.empty() or durationUnit.exists()",
            "xpath": "not(exists(f:duration)) or exists(f:durationUnit)",
            "source": "http://hl7.org/fhir/StructureDefinition/Timing"
          },
          {
            "key": "tim-10",
            "severity": "error",
            "human": "If there's a timeOfDay, there cannot be a when, or vice versa",
            "expression": "timeOfDay.empty() or when.empty()",
            "xpath": "not(exists(f:timeOfDay)) or not(exists(f:when))",
            "source": "http://hl7.org/fhir/StructureDefinition/Timing"
          },
          {
            "key": "tim-2",
            "severity": "error",
            "human": "if there's a period, there needs to be period units",
            "expression": "period.empty() or periodUnit.exists()",
            "xpath": "not(exists(f:period)) or exists(f:periodUnit)",
            "source": "http://hl7.org/fhir/StructureDefinition/Timing"
          },
          {
            "key": "tim-4",
            "severity": "error",
            "human": "duration SHALL be a non-negative value",
            "expression": "duration.exists() implies duration >= 0",
            "xpath": "f:duration/@value >= 0 or not(f:duration/@value)",
            "source": "http://hl7.org/fhir/StructureDefinition/Timing"
          }
        ],
        "isSummary": true,
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "rim",
            "map": "Implies PIVL or EIVL"
          }
        ]
      },
      {
        "id": "Dosage.timing.repeat.id",
        "path": "Dosage.timing.repeat.id",
        "representation": [
          "xmlAttr"
        ],
        "short": "Unique id for inter-element referencing",
        "definition": "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Element.id",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
                "valueUrl": "string"
              }
            ],
            "code": "http://hl7.org/fhirpath/System.String"
          }
        ],
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          }
        ]
      },
      {
        "id": "Dosage.timing.repeat.extension",
        "path": "Dosage.timing.repeat.extension",
        "slicing": {
          "discriminator": [
            {
              "type": "value",
              "path": "url"
            }
          ],
          "description": "Extensions are always sliced by (at least) url",
          "rules": "open"
        },
        "short": "Additional content defined by implementations",
        "definition": "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance  applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.",
        "comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
        "alias": [
          "extensions",
          "user content"
        ],
        "min": 0,
        "max": "*",
        "base": {
          "path": "Element.extension",
          "min": 0,
          "max": "*"
        },
        "type": [
          {
            "code": "Extension"
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          },
          {
            "key": "ext-1",
            "severity": "error",
            "human": "Must have either extensions or value[x], not both",
            "expression": "extension.exists() != value.exists()",
            "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), 'value')])",
            "source": "http://hl7.org/fhir/StructureDefinition/Extension"
          }
        ],
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "rim",
            "map": "N/A"
          }
        ]
      },
      {
        "id": "Dosage.timing.repeat.extension:timingExact",
        "path": "Dosage.timing.repeat.extension",
        "sliceName": "timingExact",
        "short": "Whether specified times must be followed as closely as possible",
        "definition": "If true, indicates that the specified times, frequencies, periods are expected to be adhered to as precisely as possible.  If false, indicates that a typical degree of variability based on institutional and/or patient convenience is acceptable.",
        "comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
        "alias": [
          "extensions",
          "user content"
        ],
        "min": 0,
        "max": "1",
        "base": {
          "path": "Element.extension",
          "min": 0,
          "max": "*"
        },
        "type": [
          {
            "code": "Extension",
            "profile": [
              "http://hl7.org/fhir/StructureDefinition/timing-exact"
            ]
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          },
          {
            "key": "ext-1",
            "severity": "error",
            "human": "Must have either extensions or value[x], not both",
            "expression": "extension.exists() != value.exists()",
            "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), 'value')])",
            "source": "http://hl7.org/fhir/StructureDefinition/Extension"
          }
        ],
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "rim",
            "map": "N/A"
          },
          {
            "identity": "v2",
            "map": "N/A"
          },
          {
            "identity": "rim",
            "map": "GTS.IsFlexible"
          }
        ]
      },
      {
        "id": "Dosage.timing.repeat.extension:timingExact.id",
        "path": "Dosage.timing.repeat.extension.id",
        "representation": [
          "xmlAttr"
        ],
        "short": "Unique id for inter-element referencing",
        "definition": "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Element.id",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
                "valueUrl": "string"
              }
            ],
            "code": "http://hl7.org/fhirpath/System.String"
          }
        ],
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          }
        ]
      },
      {
        "id": "Dosage.timing.repeat.extension:timingExact.extension",
        "path": "Dosage.timing.repeat.extension.extension",
        "slicing": {
          "discriminator": [
            {
              "type": "value",
              "path": "url"
            }
          ],
          "description": "Extensions are always sliced by (at least) url",
          "rules": "open"
        },
        "short": "Additional content defined by implementations",
        "definition": "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance  applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.",
        "comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
        "alias": [
          "extensions",
          "user content"
        ],
        "min": 0,
        "max": "0",
        "base": {
          "path": "Element.extension",
          "min": 0,
          "max": "*"
        },
        "type": [
          {
            "code": "Extension"
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          },
          {
            "key": "ext-1",
            "severity": "error",
            "human": "Must have either extensions or value[x], not both",
            "expression": "extension.exists() != value.exists()",
            "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), 'value')])",
            "source": "http://hl7.org/fhir/StructureDefinition/Extension"
          }
        ],
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "rim",
            "map": "N/A"
          }
        ]
      },
      {
        "id": "Dosage.timing.repeat.extension:timingExact.url",
        "path": "Dosage.timing.repeat.extension.url",
        "representation": [
          "xmlAttr"
        ],
        "short": "identifies the meaning of the extension",
        "definition": "Source of the definition for the extension code - a logical name or a URL.",
        "comment": "The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.",
        "min": 1,
        "max": "1",
        "base": {
          "path": "Extension.url",
          "min": 1,
          "max": "1"
        },
        "type": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
                "valueUrl": "uri"
              }
            ],
            "code": "http://hl7.org/fhirpath/System.String"
          }
        ],
        "fixedUri": "http://hl7.org/fhir/StructureDefinition/timing-exact",
        "mapping": [
          {
            "identity": "rim",
            "map": "N/A"
          }
        ]
      },
      {
        "id": "Dosage.timing.repeat.extension:timingExact.value[x]",
        "path": "Dosage.timing.repeat.extension.value[x]",
        "short": "Value of extension",
        "definition": "Indicates that the timing as specified by `.frequency`, `.period` and `.periodUnit` should be strictly interpreted. This is the case when the zib concept Interval is expressed using these elements (as opposed to the zib concept Frequency).\r\n\r\nThe times can be chosen freely, but distribution throughout the day is more precise, and the interval between times is important (e.g. in the case of antibiotics). In the case of Baxter packs and intramural care, such a prescription is used to draw up a (location-specific) outline for distribution times (logistics).",
        "comment": "Notes on the zib concepts Frequency and Interval:\n1. An interval (in FHIR) is just a normal frequency of 1 (combined with a period based on the interval length) and is represented in FHIR as just another frequency using `.frequency` (set to 1), `.period` and `.periodUnit`. However, the zib differentiates between the two concepts in the timing precision (the Interval concept defines precise intervals while the Frequency concept defines approximate intervals). When the interval is precise, this is communicated using the extension in `.extension:timingExact`.\n2. On the other hand, the zib Frequency concept might be used to express a single-use, non-repeating series by omitting the time unit. In FHIR, this is _not_ represented as a frequency, but with the `.count` element.\n3. Lastly, the Frequency concept may be used to express either a single nominal value or a range. A range is represented by respectively setting the minimum and maximum value to `.frequency` and `.frequencyMax`, or to `.count` and `.countMax` for single-use events. A nominal value is expressed by setting its value to `.frequency` or to `.count` for single-use events, and leaving `.frequencyMax` and `.countMax` unpopulated.\n\nIn summary:\n* zib concept Frequency:\n    * With time unit:\n        * Nominal value: `.frequency`, `.period` and `.periodUnit`\n        * Range: `.frequency`, `.frequencyMax`, `.period` and `.periodUnit`\n    * Without time unit:\n        * Nominal value: `.count`\n        * Range: `.count` and `.countMax`\n* zib concept Interval: `.frequency` (set to 1), `.period`, `.periodUnit` and `.extension:timingExact` (set to _true_)",
        "min": 1,
        "max": "1",
        "base": {
          "path": "Extension.value[x]",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "boolean"
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          }
        ],
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "rim",
            "map": "N/A"
          },
          {
            "identity": "zib-instructionsforuse-v1.2.1-2020EN",
            "map": "NL-CM:9.12.19950",
            "comment": "Interval (implicit, main mapping is on `.frequency`, `.period` and `.periodMax`)"
          },
          {
            "identity": "mp-dataset-mp9-300-rc1-20250522",
            "map": "mp-dataelement9x-271",
            "comment": "(negative of) IsFlexible"
          },
          {
            "identity": "mp-dataset-mp9-300-rc2-20260213",
            "map": "mp-dataelement9x-271",
            "comment": "(negative of) IsFlexible"
          },
          {
            "identity": "mp-dataset-mp9-300-rc1-20250522",
            "map": "mp-dataelement9x-672",
            "comment": "(negative of) IsFlexible"
          },
          {
            "identity": "mp-dataset-mp9-300-rc2-20260213",
            "map": "mp-dataelement9x-672",
            "comment": "(negative of) IsFlexible"
          },
          {
            "identity": "mp-dataset-mp9-300-rc1-20250522",
            "map": "mp-dataelement9x-580",
            "comment": "(negative of) IsFlexible"
          },
          {
            "identity": "mp-dataset-mp9-300-rc2-20260213",
            "map": "mp-dataelement9x-580",
            "comment": "(negative of) IsFlexible"
          },
          {
            "identity": "mp-dataset-mp9-300-rc1-20250522",
            "map": "mp-dataelement9x-412",
            "comment": "(negative of) IsFlexible"
          },
          {
            "identity": "mp-dataset-mp9-300-rc2-20260213",
            "map": "mp-dataelement9x-412",
            "comment": "(negative of) IsFlexible"
          }
        ]
      },
      {
        "id": "Dosage.timing.repeat.bounds[x]",
        "path": "Dosage.timing.repeat.bounds[x]",
        "slicing": {
          "discriminator": [
            {
              "type": "type",
              "path": "$this"
            }
          ],
          "rules": "open"
        },
        "short": "Length/Range of lengths, or (Start and/or end) limits",
        "definition": "Either a duration for the length of the timing schedule, a range of possible length, or outer bounds for start and/or end limits of the timing schedule.",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Timing.repeat.bounds[x]",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "Duration"
          },
          {
            "code": "Range"
          },
          {
            "code": "Period"
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          }
        ],
        "isSummary": true,
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "rim",
            "map": "IVL(TS) used in a QSI"
          }
        ]
      },
      {
        "id": "Dosage.timing.repeat.bounds[x]:boundsDuration",
        "path": "Dosage.timing.repeat.bounds[x]",
        "sliceName": "boundsDuration",
        "short": "DoseDuration",
        "definition": "The intended time duration for these dosing instructions, e.g. 5 days or 8 weeks. \r\nIn the case of medication for an indefinite period, the dosing duration is left empty in the last dosing instruction.",
        "alias": [
          "Doseerduur"
        ],
        "min": 0,
        "max": "1",
        "base": {
          "path": "Timing.repeat.bounds[x]",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "Duration"
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          }
        ],
        "isSummary": true,
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "rim",
            "map": "IVL(TS) used in a QSI"
          },
          {
            "identity": "zib-instructionsforuse-v1.2.1-2020EN",
            "map": "NL-CM:9.12.22506",
            "comment": "DoseDuration"
          }
        ]
      },
      {
        "id": "Dosage.timing.repeat.count",
        "path": "Dosage.timing.repeat.count",
        "short": "Frequency / minimumValue / nominalValue",
        "definition": "Usually, frequency comprises both amount and time unit (3 times a day), but it can occur without the time unit (single use). This is represented by this `.count` element and optionally `.countMax` if a range should be represented.",
        "comment": "Notes on the zib concept Frequency can be found in the comment of the `.frequency` element.",
        "requirements": "Repetitions may be limited by end time or total occurrences.",
        "alias": [
          "Frequentie",
          "nominaleWaarde",
          "minimumWaarde"
        ],
        "min": 0,
        "max": "1",
        "base": {
          "path": "Timing.repeat.count",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "positiveInt"
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          }
        ],
        "isSummary": true,
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "rim",
            "map": "PIVL.count"
          },
          {
            "identity": "zib-instructionsforuse-v1.2.1-2020EN",
            "map": "NL-CM:9.12.19949",
            "comment": "Frequency (single use only)"
          },
          {
            "identity": "zib-range-v1.0.1-2020EN",
            "map": "NL-CM:20.1.2",
            "comment": "minimumValue"
          },
          {
            "identity": "zib-range-v1.0.1-2020EN",
            "map": "NL-CM:20.1.4",
            "comment": "nominalValue"
          }
        ]
      },
      {
        "id": "Dosage.timing.repeat.countMax",
        "path": "Dosage.timing.repeat.countMax",
        "short": "Frequency / maximumValue",
        "definition": "Usually, frequency comprises both amount and time unit (3 times a day), but it can occur without the time unit (single use). This is represented by the `.count` element and optionally `.countMax` if a range should be represented.",
        "comment": "Notes on the zib concept Frequency can be found in the comment of the `.frequency` element.",
        "alias": [
          "Frequentie",
          "maximumWaarde"
        ],
        "min": 0,
        "max": "1",
        "base": {
          "path": "Timing.repeat.countMax",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "positiveInt"
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          }
        ],
        "isSummary": true,
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "rim",
            "map": "PIVL.count"
          },
          {
            "identity": "zib-instructionsforuse-v1.2.1-2020EN",
            "map": "NL-CM:9.12.19949",
            "comment": "Frequency"
          },
          {
            "identity": "zib-range-v1.0.1-2020EN",
            "map": "NL-CM:20.1.3",
            "comment": "maximumValue"
          }
        ]
      },
      {
        "id": "Dosage.timing.repeat.duration",
        "path": "Dosage.timing.repeat.duration",
        "short": "DurationOfAdministration",
        "definition": "The duration of administration defines the length of time during which the drug is administered and is mainly used in the slow parenteral administration of fluids. The `durationUnit` defines the time unit.",
        "comment": "For some events the duration is part of the definition of the event (e.g. IV infusions, where the duration is implicit in the specified quantity and rate). For others, it's part of the timing specification (e.g. exercise).",
        "requirements": "Some activities are not instantaneous and need to be maintained for a period of time.",
        "alias": [
          "Toedieningsduur"
        ],
        "min": 0,
        "max": "1",
        "base": {
          "path": "Timing.repeat.duration",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "decimal"
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          }
        ],
        "isSummary": true,
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "rim",
            "map": "PIVL.phase"
          },
          {
            "identity": "zib-instructionsforuse-v1.2.1-2020EN",
            "map": "NL-CM:9.12.23141",
            "comment": "DurationOfAdministration"
          }
        ]
      },
      {
        "id": "Dosage.timing.repeat.durationMax",
        "path": "Dosage.timing.repeat.durationMax",
        "short": "How long when it happens (Max)",
        "definition": "If present, indicates that the duration is a range - so to perform the action between [duration] and [durationMax] time length.",
        "comment": "For some events the duration is part of the definition of the event (e.g. IV infusions, where the duration is implicit in the specified quantity and rate). For others, it's part of the timing specification (e.g. exercise).",
        "requirements": "Some activities are not instantaneous and need to be maintained for a period of time.",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Timing.repeat.durationMax",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "decimal"
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          }
        ],
        "isSummary": true,
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "rim",
            "map": "PIVL.phase"
          }
        ]
      },
      {
        "id": "Dosage.timing.repeat.durationUnit",
        "path": "Dosage.timing.repeat.durationUnit",
        "short": "DurationOfAdministration",
        "definition": "The units of time, in UCUM units, for the duration of administration of time during which the drug is administered.",
        "comment": "Note that FHIR strings SHALL NOT exceed 1MB in size",
        "alias": [
          "Toedieningsduur"
        ],
        "min": 0,
        "max": "1",
        "base": {
          "path": "Timing.repeat.durationUnit",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "code"
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          }
        ],
        "isSummary": true,
        "binding": {
          "extension": [
            {
              "url": "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName",
              "valueString": "UnitsOfTime"
            }
          ],
          "strength": "required",
          "description": "A unit of time (units from UCUM).",
          "valueSet": "http://hl7.org/fhir/ValueSet/units-of-time|4.0.1"
        },
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "rim",
            "map": "PIVL.phase.unit"
          },
          {
            "identity": "zib-instructionsforuse-v1.2.1-2020EN",
            "map": "NL-CM:9.12.23141",
            "comment": "DurationOfAdministration"
          }
        ]
      },
      {
        "id": "Dosage.timing.repeat.frequency",
        "path": "Dosage.timing.repeat.frequency",
        "short": "Frequency / minimumValue / nominalValue / Interval",
        "definition": "The `.frequency` element indicates either the number of dose moments per time unit (zib concept Frequency) or the time between dose times (zib concept Interval).\r\n\r\nIf `.frequencyMax` is present, this `.frequency`  element indicates the lower bound of the allowed range of the frequency.",
        "comment": "Notes on the zib concepts Frequency and Interval, The zib differentiates between the two concepts in the specific usage of the extension `.extension:timingExact` and the element `.timeOfDay` combined:\n1. The zib Interval (in FHIR) is just a normal frequency of 1 (combined with a period based on the interval length) and is represented in FHIR as just another frequency using `.frequency` (set to 1), `.period`, `.periodUnit`, the extension `.extension:timingExact` set to _true_ and the absence of the element `.timeOfDay`.\n2. The zib Frequency concept might be used to express a single-use, non-repeating series by omitting the time unit. In FHIR, this is _not_ represented as a frequency, but with the `.count` element.\n3. Lastly, the Frequency concept may be used to express either a single nominal value or a range. The extension `.extension:timingExact` can be used to specify the precision of the timing of the administration (i.e. the element `.timeOfDay`). When this element is meant to convey the zib Frequency concept this can be, unlike the zib concept Interval, either _true_or _false_. A range is represented by respectively setting the minimum and maximum value to `.frequency` and `.frequencyMax`, or to `.count` and `.countMax` for single-use events as mentioned in the second point. A nominal value is expressed by setting its value to `.frequency` or to `.count` for single-use events, and leaving `.frequencyMax` and `.countMax` unpopulated.\n\nIn summary:\n* zib concept Frequency:\n    * With time unit (precision of the timing can be further specified with the extension `.extension:timingExact`):\n        * Nominal value: `.frequency`, `.period` and `.periodUnit`\n        * Range: `.frequency`, `.frequencyMax`, `.period` and `.periodUnit`\n    * Without time unit:\n        * Nominal value: `.count`\n        * Range: `.count` and `.countMax`\n* zib concept Interval: `.frequency` (set to 1), `.period`, `.periodUnit`, `.extension:timingExact` (SHALL be set to _true_) and the absence of `.timeOfDay`.",
        "alias": [
          "Frequentie",
          "minimumWaarde",
          "nominaleWaarde",
          "Interval"
        ],
        "min": 0,
        "max": "1",
        "base": {
          "path": "Timing.repeat.frequency",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "positiveInt"
          }
        ],
        "meaningWhenMissing": "If no frequency is stated, the assumption is that the event occurs once per period, but systems SHOULD always be specific about this",
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          }
        ],
        "isSummary": true,
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "rim",
            "map": "PIVL.phase"
          },
          {
            "identity": "zib-instructionsforuse-v1.2.1-2020EN",
            "map": "NL-CM:9.12.19949",
            "comment": "Frequency"
          },
          {
            "identity": "zib-range-v1.0.1-2020EN",
            "map": "NL-CM:20.1.2",
            "comment": "minimumValue"
          },
          {
            "identity": "zib-range-v1.0.1-2020EN",
            "map": "NL-CM:20.1.4",
            "comment": "nominalValue"
          },
          {
            "identity": "zib-instructionsforuse-v1.2.1-2020EN",
            "map": "NL-CM:9.12.19950",
            "comment": "Interval"
          }
        ]
      },
      {
        "id": "Dosage.timing.repeat.frequencyMax",
        "path": "Dosage.timing.repeat.frequencyMax",
        "short": "Frequency / maximumValue",
        "definition": "If present, indicates that the frequency is a range - so to repeat between [frequency] and [frequencyMax] times within the period or period range.",
        "comment": "Notes on the zib concept Frequency can be found in the comment of the `.frequency` element.",
        "alias": [
          "maximumWaarde",
          "Frequentie"
        ],
        "min": 0,
        "max": "1",
        "base": {
          "path": "Timing.repeat.frequencyMax",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "positiveInt"
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          }
        ],
        "isSummary": true,
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "rim",
            "map": "PIVL.phase"
          },
          {
            "identity": "zib-instructionsforuse-v1.2.1-2020EN",
            "map": "NL-CM:9.12.19949",
            "comment": "Frequency"
          },
          {
            "identity": "zib-range-v1.0.1-2020EN",
            "map": "NL-CM:20.1.3",
            "comment": "maximumValue"
          }
        ]
      },
      {
        "id": "Dosage.timing.repeat.period",
        "path": "Dosage.timing.repeat.period",
        "short": "Frequency / Interval",
        "definition": "Indicates the duration of time over which repetitions are to occur; e.g. to express \"3 times per day\", 3 would be the frequency and \"1 day\" would be the period. If `.periodMax` is present, this element indicates the lower bound of the allowed range of the period length.",
        "comment": "Notes on the zib concepts Frequency and Interval can be found in the comment of the `.frequency` element.",
        "alias": [
          "Frequentie",
          "Interval"
        ],
        "min": 0,
        "max": "1",
        "base": {
          "path": "Timing.repeat.period",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "decimal"
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          }
        ],
        "isSummary": true,
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "rim",
            "map": "PIVL.phase"
          },
          {
            "identity": "zib-instructionsforuse-v1.2.1-2020EN",
            "map": "NL-CM:9.12.19949",
            "comment": "Frequency"
          },
          {
            "identity": "zib-instructionsforuse-v1.2.1-2020EN",
            "map": "NL-CM:9.12.19950",
            "comment": "Interval"
          }
        ]
      },
      {
        "id": "Dosage.timing.repeat.periodMax",
        "path": "Dosage.timing.repeat.periodMax",
        "short": "Upper limit of period (3-4 hours)",
        "definition": "If present, indicates that the period is a range from [period] to [periodMax], allowing expressing concepts such as \"do this once every 3-5 days.",
        "comment": "Do not use an IEEE type floating point type, instead use something that works like a true decimal, with inbuilt precision (e.g. Java BigInteger)",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Timing.repeat.periodMax",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "decimal"
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          }
        ],
        "isSummary": true,
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "rim",
            "map": "PIVL.phase"
          }
        ]
      },
      {
        "id": "Dosage.timing.repeat.periodUnit",
        "path": "Dosage.timing.repeat.periodUnit",
        "short": "Frequency / Interval",
        "definition": "The units of time for the period in UCUM units for Frequency and Interval.",
        "comment": "Notes on the zib concepts Frequency and Interval can be found in the comment of the `.frequency` element.",
        "alias": [
          "Frequentie",
          "Interval"
        ],
        "min": 0,
        "max": "1",
        "base": {
          "path": "Timing.repeat.periodUnit",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "code"
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          }
        ],
        "isSummary": true,
        "binding": {
          "extension": [
            {
              "url": "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName",
              "valueString": "UnitsOfTime"
            }
          ],
          "strength": "required",
          "description": "A unit of time (units from UCUM).",
          "valueSet": "http://hl7.org/fhir/ValueSet/units-of-time|4.0.1"
        },
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "rim",
            "map": "PIVL.phase.unit"
          },
          {
            "identity": "zib-instructionsforuse-v1.2.1-2020EN",
            "map": "NL-CM:9.12.19949",
            "comment": "Frequency. When frequency is used, set `.extension.timingExact` to false."
          },
          {
            "identity": "zib-instructionsforuse-v1.2.1-2020EN",
            "map": "NL-CM:9.12.19950",
            "comment": "Interval"
          }
        ]
      },
      {
        "id": "Dosage.timing.repeat.dayOfWeek",
        "path": "Dosage.timing.repeat.dayOfWeek",
        "short": "WeekDay",
        "definition": "WeekDay indicates a pattern of doses on fixed week days.",
        "comment": "If no days are specified, the action is assumed to happen every day as otherwise specified.",
        "alias": [
          "Weekdag"
        ],
        "min": 0,
        "max": "*",
        "base": {
          "path": "Timing.repeat.dayOfWeek",
          "min": 0,
          "max": "*"
        },
        "type": [
          {
            "code": "code"
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          }
        ],
        "isSummary": true,
        "binding": {
          "extension": [
            {
              "url": "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName",
              "valueString": "DayOfWeek"
            }
          ],
          "strength": "required",
          "description": "Use ConceptMap 'WeekdagCodelijst_to_DaysOfWeek' to translate zib terminology to profile terminology in ValueSet 'DaysOfWeek'",
          "valueSet": "http://hl7.org/fhir/ValueSet/days-of-week|4.0.1",
          "_valueSet": {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/11179-permitted-value-conceptmap",
                "valueCanonical": "http://nictiz.nl/fhir/ConceptMap/WeekdagCodelijst-to-DaysOfWeek"
              }
            ]
          }
        },
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "zib-instructionsforuse-v1.2.1-2020EN",
            "map": "NL-CM:9.12.19952",
            "comment": "WeekDay"
          }
        ]
      },
      {
        "id": "Dosage.timing.repeat.timeOfDay",
        "path": "Dosage.timing.repeat.timeOfDay",
        "short": "AdministrationTime",
        "definition": "The time of administration is a specific time of day (on the clock). This time usually isn’t (intended to be) exact. There can be multiple administering times in one day. \r\n\r\nThe ideal time of administration can also be entered as a time of day (morning, afternoon, evening, night-time). The administration time is then to be left empty, and the time of day can be entered in the TimeOfDay concept.",
        "comment": "If there's a `.timeOfDay`, there cannot be a `.when`, or vice versa.",
        "alias": [
          "Toedientijd"
        ],
        "min": 0,
        "max": "*",
        "base": {
          "path": "Timing.repeat.timeOfDay",
          "min": 0,
          "max": "*"
        },
        "type": [
          {
            "code": "time"
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          }
        ],
        "isSummary": true,
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "zib-instructionsforuse-v1.2.1-2020EN",
            "map": "NL-CM:9.12.19951",
            "comment": "AdministrationTime"
          }
        ]
      },
      {
        "id": "Dosage.timing.repeat.when",
        "path": "Dosage.timing.repeat.when",
        "short": "TimeOfDay",
        "definition": "Time of day: morning, afternoon, evening, night.",
        "comment": "If there's a `.timeOfDay`, there cannot be a `.when`, or vice versa.",
        "requirements": "Timings are frequently determined by occurrences such as waking, eating and sleep.",
        "alias": [
          "Dagdeel"
        ],
        "min": 0,
        "max": "*",
        "base": {
          "path": "Timing.repeat.when",
          "min": 0,
          "max": "*"
        },
        "type": [
          {
            "code": "code"
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          }
        ],
        "isSummary": true,
        "binding": {
          "extension": [
            {
              "url": "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName",
              "valueString": "EventTiming"
            }
          ],
          "strength": "required",
          "description": "Use ConceptMap 'DagdeelCodelijst_to_EventTiming' to translate zib terminology to profile terminology in ValueSet 'EventTiming'",
          "valueSet": "http://hl7.org/fhir/ValueSet/event-timing",
          "_valueSet": {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/11179-permitted-value-conceptmap",
                "valueCanonical": "http://nictiz.nl/fhir/ConceptMap/DagdeelCodelijst-to-EventTiming"
              }
            ]
          }
        },
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "rim",
            "map": "EIVL.event"
          },
          {
            "identity": "zib-instructionsforuse-v1.2.1-2020EN",
            "map": "NL-CM:9.12.19953",
            "comment": "TimeOfDay"
          }
        ]
      },
      {
        "id": "Dosage.timing.repeat.offset",
        "path": "Dosage.timing.repeat.offset",
        "short": "Minutes from event (before or after)",
        "definition": "The number of minutes from the event. If the event code does not indicate whether the minutes is before or after the event, then the offset is assumed to be after the event.",
        "comment": "32 bit number; for values larger than this, use decimal",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Timing.repeat.offset",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "unsignedInt"
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          }
        ],
        "isSummary": true,
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "rim",
            "map": "EIVL.offset"
          }
        ]
      },
      {
        "id": "Dosage.timing.code",
        "path": "Dosage.timing.code",
        "short": "BID | TID | QID | AM | PM | QD | QOD | +",
        "definition": "A code for the timing schedule (or just text in code.text). Some codes such as BID are ubiquitous, but many institutions define their own additional codes. If a code is provided, the code is understood to be a complete statement of whatever is specified in the structured timing data, and either the code or the data may be used to interpret the Timing, with the exception that .repeat.bounds still applies over the code (and is not contained in the code).",
        "comment": "BID etc. are defined as 'at institutionally specified times'. For example, an institution may choose that BID is \"always at 7am and 6pm\".  If it is inappropriate for this choice to be made, the code BID should not be used. Instead, a distinct organization-specific code should be used in place of the HL7-defined BID code and/or a structured representation should be used (in this case, specifying the two event times).",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Timing.code",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "CodeableConcept"
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          }
        ],
        "isSummary": true,
        "binding": {
          "extension": [
            {
              "url": "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName",
              "valueString": "TimingAbbreviation"
            }
          ],
          "strength": "preferred",
          "description": "Code for a known / defined timing pattern.",
          "valueSet": "http://hl7.org/fhir/ValueSet/timing-abbreviation"
        },
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "v2",
            "map": "CE/CNE/CWE"
          },
          {
            "identity": "rim",
            "map": "CD"
          },
          {
            "identity": "orim",
            "map": "fhir:CodeableConcept rdfs:subClassOf dt:CD"
          },
          {
            "identity": "rim",
            "map": "QSC.code"
          }
        ]
      },
      {
        "id": "Dosage.asNeeded[x]",
        "path": "Dosage.asNeeded[x]",
        "slicing": {
          "discriminator": [
            {
              "type": "type",
              "path": "$this"
            }
          ],
          "rules": "open"
        },
        "short": "Take \"as needed\" (for x)",
        "definition": "Indicates whether the Medication is only taken when needed within a specific dosing schedule (Boolean option), or it indicates the precondition for taking the Medication (CodeableConcept).",
        "comment": "Can express \"as needed\" without a reason by setting the Boolean = True.  In this case the CodeableConcept is not populated.  Or you can express \"as needed\" with a reason by including the CodeableConcept.  In this case the Boolean is assumed to be True.  If you set the Boolean to False, then the dose is given according to the schedule and is not \"prn\" or \"as needed\".",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Dosage.asNeeded[x]",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "boolean"
          },
          {
            "code": "CodeableConcept"
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          }
        ],
        "isSummary": true,
        "binding": {
          "extension": [
            {
              "url": "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName",
              "valueString": "MedicationAsNeededReason"
            }
          ],
          "strength": "example",
          "description": "A coded concept identifying the precondition that should be met or evaluated prior to consuming or administering a medication dose.  For example \"pain\", \"30 minutes prior to sexual intercourse\", \"on flare-up\" etc.",
          "valueSet": "http://hl7.org/fhir/ValueSet/medication-as-needed-reason"
        },
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "v2",
            "map": "TQ1-9"
          },
          {
            "identity": "rim",
            "map": ".outboundRelationship[typeCode=PRCN].target[classCode=OBS, moodCode=EVN, code=\"as needed\"].value=boolean or codable concept"
          }
        ]
      },
      {
        "id": "Dosage.asNeeded[x]:asNeededCodeableConcept",
        "path": "Dosage.asNeeded[x]",
        "sliceName": "asNeededCodeableConcept",
        "short": "Condition",
        "definition": "Condition for administration of medication can be:\r\n\r\n*a measured physiological value (plasma glucose level, body temperature, blood pressure);\r\n*a symptom or other condition (headache, itching).\r\n\r\nRelevant “as needed” conditions from NHG Table 25 form the value list for transmitting this concept in coded form. The conditions supported in the G-standard are included in file 362. The textual description of that code must always be provided as well.\r\n\r\nPhysiological measurements or other conditions that are not included in the “as needed” conditions of NHG Table 25 can be expressed in free text using the OTH code.",
        "comment": "If only one 'asNeeded' concept is exchanged within a Dosage, use Dosage.asNeeded[x]. Otherwise use the extension Dosage.extension:asNeeded.value[x] for when multiple 'asNeeded' concepts are to be exchanged.\r\n\r\nCan express \"as needed\" without a reason by setting the Boolean = True.  In this case the CodeableConcept is not populated.  Or you can express \"as needed\" with a reason by including the CodeableConcept.  In this case the Boolean is assumed to be True.  If you set the Boolean to False, then the dose is given according to the schedule and is not \"prn\" or \"as needed\".",
        "alias": [
          "Criterium"
        ],
        "min": 0,
        "max": "1",
        "base": {
          "path": "Dosage.asNeeded[x]",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "CodeableConcept"
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          }
        ],
        "isSummary": true,
        "binding": {
          "extension": [
            {
              "url": "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName",
              "valueString": "MedicationAsNeededReason"
            }
          ],
          "strength": "required",
          "description": "A coded concept identifying the precondition that should be met or evaluated prior to consuming or administering a medication dose.  For example \"pain\", \"30 minutes prior to sexual intercourse\", \"on flare-up\" etc.",
          "valueSet": "http://decor.nictiz.nl/fhir/ValueSet/2.16.840.1.113883.2.4.3.11.60.40.2.9.12.4--20200901000000"
        },
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "v2",
            "map": "TQ1-9"
          },
          {
            "identity": "rim",
            "map": ".outboundRelationship[typeCode=PRCN].target[classCode=OBS, moodCode=EVN, code=\"as needed\"].value=boolean or codable concept"
          },
          {
            "identity": "zib-instructionsforuse-v1.2.1-2020EN",
            "map": "NL-CM:9.12.19945",
            "comment": "Condition [DEPRECATED]"
          },
          {
            "identity": "mp-dataset-mp9-300-rc2-20260213",
            "map": "mp-dataelement9x-321",
            "comment": "Condition"
          },
          {
            "identity": "mp-dataset-mp9-300-rc2-20260213",
            "map": "mp-dataelement9x-72",
            "comment": "Condition"
          },
          {
            "identity": "mp-dataset-mp9-300-rc2-20260213",
            "map": "mp-dataelement9x-389",
            "comment": "Condition"
          },
          {
            "identity": "mp-dataset-mp9-300-rc2-20260213",
            "map": "mp-dataelement9x-676",
            "comment": "Condition"
          }
        ]
      },
      {
        "id": "Dosage.asNeeded[x]:asNeededCodeableConcept.id",
        "path": "Dosage.asNeeded[x].id",
        "representation": [
          "xmlAttr"
        ],
        "short": "Unique id for inter-element referencing",
        "definition": "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Element.id",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
                "valueUrl": "string"
              }
            ],
            "code": "http://hl7.org/fhirpath/System.String"
          }
        ],
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          }
        ]
      },
      {
        "id": "Dosage.asNeeded[x]:asNeededCodeableConcept.extension",
        "path": "Dosage.asNeeded[x].extension",
        "slicing": {
          "discriminator": [
            {
              "type": "value",
              "path": "url"
            }
          ],
          "description": "Extensions are always sliced by (at least) url",
          "rules": "open"
        },
        "short": "Additional content defined by implementations",
        "definition": "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance  applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.",
        "comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
        "alias": [
          "extensions",
          "user content"
        ],
        "min": 0,
        "max": "*",
        "base": {
          "path": "Element.extension",
          "min": 0,
          "max": "*"
        },
        "type": [
          {
            "code": "Extension"
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          },
          {
            "key": "ext-1",
            "severity": "error",
            "human": "Must have either extensions or value[x], not both",
            "expression": "extension.exists() != value.exists()",
            "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), 'value')])",
            "source": "http://hl7.org/fhir/StructureDefinition/Extension"
          }
        ],
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "rim",
            "map": "N/A"
          }
        ]
      },
      {
        "id": "Dosage.asNeeded[x]:asNeededCodeableConcept.coding",
        "path": "Dosage.asNeeded[x].coding",
        "short": "Code defined by a terminology system",
        "definition": "A reference to a code defined by a terminology system.",
        "comment": "Codes may be defined very casually in enumerations, or code lists, up to very formal definitions such as SNOMED CT - see the HL7 v3 Core Principles for more information.  Ordering of codings is undefined and SHALL NOT be used to infer meaning. Generally, at most only one of the coding values will be labeled as UserSelected = true.",
        "requirements": "Allows for alternative encodings within a code system, and translations to other code systems.",
        "min": 0,
        "max": "*",
        "base": {
          "path": "CodeableConcept.coding",
          "min": 0,
          "max": "*"
        },
        "type": [
          {
            "code": "Coding"
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          }
        ],
        "isSummary": true,
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "v2",
            "map": "CE/CNE/CWE subset one of the sets of component 1-3 or 4-6"
          },
          {
            "identity": "rim",
            "map": "CV"
          },
          {
            "identity": "orim",
            "map": "fhir:Coding rdfs:subClassOf dt:CDCoding"
          },
          {
            "identity": "v2",
            "map": "C*E.1-8, C*E.10-22"
          },
          {
            "identity": "rim",
            "map": "union(., ./translation)"
          },
          {
            "identity": "orim",
            "map": "fhir:CodeableConcept.coding rdfs:subPropertyOf dt:CD.coding"
          }
        ]
      },
      {
        "id": "Dosage.asNeeded[x]:asNeededCodeableConcept.text",
        "extension": [
          {
            "url": "http://hl7.org/fhir/StructureDefinition/elementdefinition-translatable",
            "valueBoolean": true
          }
        ],
        "path": "Dosage.asNeeded[x].text",
        "short": "Plain text representation of the concept",
        "definition": "A human language representation of the concept as seen/selected/uttered by the user who entered the data and/or which represents the intended meaning of the user.",
        "comment": "Very often the text is the same as a displayName of one of the codings.",
        "requirements": "The codes from the terminologies do not always capture the correct meaning with all the nuances of the human using them, or sometimes there is no appropriate code at all. In these cases, the text is used to capture the full meaning of the source.",
        "min": 0,
        "max": "1",
        "base": {
          "path": "CodeableConcept.text",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "string"
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          }
        ],
        "isSummary": true,
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "v2",
            "map": "C*E.9. But note many systems use C*E.2 for this"
          },
          {
            "identity": "rim",
            "map": "./originalText[mediaType/code=\"text/plain\"]/data"
          },
          {
            "identity": "orim",
            "map": "fhir:CodeableConcept.text rdfs:subPropertyOf dt:CD.originalText"
          },
          {
            "identity": "mp-dataset-mp9-300-rc1-20250522",
            "map": "mp-dataelement9x-272",
            "comment": "Description"
          },
          {
            "identity": "mp-dataset-mp9-300-rc2-20260213",
            "map": "mp-dataelement9x-272",
            "comment": "Description"
          },
          {
            "identity": "mp-dataset-mp9-300-rc1-20250522",
            "map": "mp-dataelement9x-677",
            "comment": "Description"
          },
          {
            "identity": "mp-dataset-mp9-300-rc2-20260213",
            "map": "mp-dataelement9x-677",
            "comment": "Description"
          },
          {
            "identity": "mp-dataset-mp9-300-rc1-20250522",
            "map": "mp-dataelement9x-582",
            "comment": "Description"
          },
          {
            "identity": "mp-dataset-mp9-300-rc2-20260213",
            "map": "mp-dataelement9x-582",
            "comment": "Description"
          },
          {
            "identity": "mp-dataset-mp9-300-rc1-20250522",
            "map": "mp-dataelement9x-514",
            "comment": "Description"
          },
          {
            "identity": "mp-dataset-mp9-300-rc2-20260213",
            "map": "mp-dataelement9x-514",
            "comment": "Description"
          }
        ]
      },
      {
        "id": "Dosage.site",
        "path": "Dosage.site",
        "short": "Body site to administer to",
        "definition": "Body site to administer to.",
        "comment": "If the use case requires attributes from the BodySite resource (e.g. to identify and track separately) then use the standard extension [bodySite](extension-bodysite.html).  May be a summary code, or a reference to a very precise definition of the location, or both.",
        "requirements": "A coded specification of the anatomic site where the medication first enters the body.",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Dosage.site",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "CodeableConcept"
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          }
        ],
        "isSummary": true,
        "binding": {
          "extension": [
            {
              "url": "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName",
              "valueString": "MedicationAdministrationSite"
            }
          ],
          "strength": "example",
          "description": "A coded concept describing the site location the medicine enters into or onto the body.",
          "valueSet": "http://hl7.org/fhir/ValueSet/approach-site-codes"
        },
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "v2",
            "map": "CE/CNE/CWE"
          },
          {
            "identity": "rim",
            "map": "CD"
          },
          {
            "identity": "orim",
            "map": "fhir:CodeableConcept rdfs:subClassOf dt:CD"
          },
          {
            "identity": "v2",
            "map": "RXR-2"
          },
          {
            "identity": "rim",
            "map": ".approachSiteCode"
          }
        ]
      },
      {
        "id": "Dosage.route",
        "path": "Dosage.route",
        "short": "RouteOfAdministration",
        "definition": "The route through which the medication is administered (oral, nasal, intravenous, etc.). The routes of administration supported in the G-standard are included in file 902, thesaurus number 7.",
        "comment": "Please note that in contrast to the zib, this RouteOfAdministration concept is grouped under the DosingInstructions concept. This `.route` element shall have the same value when there are multiple DosingInstructions.",
        "requirements": "A code specifying the route or physiological path of administration of a therapeutic agent into or onto a patient's body.",
        "alias": [
          "Toedieningsweg"
        ],
        "min": 0,
        "max": "1",
        "base": {
          "path": "Dosage.route",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "CodeableConcept"
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          }
        ],
        "isSummary": true,
        "binding": {
          "extension": [
            {
              "url": "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName",
              "valueString": "RouteOfAdministration"
            }
          ],
          "strength": "required",
          "description": "A coded concept describing the route or physiological path of administration of a therapeutic agent into or onto the body of a subject.",
          "valueSet": "http://decor.nictiz.nl/fhir/ValueSet/2.16.840.1.113883.2.4.3.11.60.40.2.9.12.1--20200901000000"
        },
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "v2",
            "map": "CE/CNE/CWE"
          },
          {
            "identity": "rim",
            "map": "CD"
          },
          {
            "identity": "orim",
            "map": "fhir:CodeableConcept rdfs:subClassOf dt:CD"
          },
          {
            "identity": "v2",
            "map": "RXR-1"
          },
          {
            "identity": "rim",
            "map": ".routeCode"
          },
          {
            "identity": "zib-instructionsforuse-v1.2.1-2020EN",
            "map": "NL-CM:9.12.19941",
            "comment": "RouteOfAdministration [DEPRECATED]"
          },
          {
            "identity": "mp-dataset-mp9-300-rc2-20260213",
            "map": "mp-dataelement9x-303",
            "comment": "RouteOfAdministration"
          },
          {
            "identity": "mp-dataset-mp9-300-rc2-20260213",
            "map": "mp-dataelement9x-430",
            "comment": "RouteOfAdministration"
          },
          {
            "identity": "mp-dataset-mp9-300-rc2-20260213",
            "map": "mp-dataelement9x-54",
            "comment": "RouteOfAdministration"
          },
          {
            "identity": "mp-dataset-mp9-300-rc2-20260213",
            "map": "mp-dataelement9x-371",
            "comment": "RouteOfAdministration"
          },
          {
            "identity": "mp-dataset-mp9-300-rc2-20260213",
            "map": "mp-dataelement9x-648",
            "comment": "RouteOfAdministration"
          }
        ]
      },
      {
        "id": "Dosage.method",
        "path": "Dosage.method",
        "short": "Technique for administering medication",
        "definition": "Technique for administering medication.",
        "comment": "Terminologies used often pre-coordinate this term with the route and or form of administration.",
        "requirements": "A coded value indicating the method by which the medication is introduced into or onto the body. Most commonly used for injections.  For examples, Slow Push; Deep IV.",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Dosage.method",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "CodeableConcept"
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          }
        ],
        "isSummary": true,
        "binding": {
          "extension": [
            {
              "url": "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName",
              "valueString": "MedicationAdministrationMethod"
            }
          ],
          "strength": "example",
          "description": "A coded concept describing the technique by which the medicine is administered.",
          "valueSet": "http://hl7.org/fhir/ValueSet/administration-method-codes"
        },
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "v2",
            "map": "CE/CNE/CWE"
          },
          {
            "identity": "rim",
            "map": "CD"
          },
          {
            "identity": "orim",
            "map": "fhir:CodeableConcept rdfs:subClassOf dt:CD"
          },
          {
            "identity": "v2",
            "map": "RXR-4"
          },
          {
            "identity": "rim",
            "map": ".doseQuantity"
          }
        ]
      },
      {
        "id": "Dosage.doseAndRate",
        "path": "Dosage.doseAndRate",
        "short": "Amount of medication administered",
        "definition": "The amount of medication administered.",
        "min": 0,
        "max": "*",
        "base": {
          "path": "Dosage.doseAndRate",
          "min": 0,
          "max": "*"
        },
        "type": [
          {
            "code": "Element"
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          }
        ],
        "isSummary": true,
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "v2",
            "map": "TQ1-2"
          }
        ]
      },
      {
        "id": "Dosage.doseAndRate.id",
        "path": "Dosage.doseAndRate.id",
        "representation": [
          "xmlAttr"
        ],
        "short": "Unique id for inter-element referencing",
        "definition": "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Element.id",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
                "valueUrl": "string"
              }
            ],
            "code": "http://hl7.org/fhirpath/System.String"
          }
        ],
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          }
        ]
      },
      {
        "id": "Dosage.doseAndRate.extension",
        "path": "Dosage.doseAndRate.extension",
        "slicing": {
          "discriminator": [
            {
              "type": "value",
              "path": "url"
            }
          ],
          "description": "Extensions are always sliced by (at least) url",
          "rules": "open"
        },
        "short": "Additional content defined by implementations",
        "definition": "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance  applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.",
        "comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
        "alias": [
          "extensions",
          "user content"
        ],
        "min": 0,
        "max": "*",
        "base": {
          "path": "Element.extension",
          "min": 0,
          "max": "*"
        },
        "type": [
          {
            "code": "Extension"
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          },
          {
            "key": "ext-1",
            "severity": "error",
            "human": "Must have either extensions or value[x], not both",
            "expression": "extension.exists() != value.exists()",
            "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), 'value')])",
            "source": "http://hl7.org/fhir/StructureDefinition/Extension"
          }
        ],
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "rim",
            "map": "N/A"
          }
        ]
      },
      {
        "id": "Dosage.doseAndRate.type",
        "path": "Dosage.doseAndRate.type",
        "short": "The kind of dose or rate specified",
        "definition": "The kind of dose or rate specified, for example, ordered or calculated.",
        "comment": "Not all terminology uses fit this general pattern. In some cases, models should not use CodeableConcept and use Coding directly and provide their own structure for managing text, codings, translations and the relationship between elements and pre- and post-coordination.",
        "requirements": "If the type is not populated, assume to be \"ordered\".",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Dosage.doseAndRate.type",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "CodeableConcept"
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          }
        ],
        "isSummary": true,
        "binding": {
          "extension": [
            {
              "url": "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName",
              "valueString": "DoseAndRateType"
            }
          ],
          "strength": "example",
          "description": "The kind of dose or rate specified.",
          "valueSet": "http://hl7.org/fhir/ValueSet/dose-rate-type"
        },
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "v2",
            "map": "CE/CNE/CWE"
          },
          {
            "identity": "rim",
            "map": "CD"
          },
          {
            "identity": "orim",
            "map": "fhir:CodeableConcept rdfs:subClassOf dt:CD"
          },
          {
            "identity": "v2",
            "map": "RXO-21; RXE-23"
          }
        ]
      },
      {
        "id": "Dosage.doseAndRate.dose[x]",
        "path": "Dosage.doseAndRate.dose[x]",
        "slicing": {
          "discriminator": [
            {
              "type": "type",
              "path": "$this"
            }
          ],
          "rules": "open"
        },
        "short": "Dose",
        "definition": "The dose indicates the amount/unit per administration. The unit can be any unit that can occur with this particular medicine. For liquids and other divisible products, a volume measure (preferably \"ml\") will usually be used.\r\n\r\nIn many cases, the prescriber may want to specify the dosage in units of weight of the active substance.\r\n\r\nIf only the substance is indicated and not the product, then the amount of that substance is specified. For example, Paracetamol 1000 mg is equivalent to Paracetamol 500 mg tablets, 2 tablets (or units).\r\n\r\nThe dosage is sometimes indicated in a calculation, which often uses the patient's body weight or body surface area as a parameter. However, the calculation remains nothing more than a tool to aid decision-making.\r\n\r\nIn continuous administration, alongside the administration speed, the dose can be specified (e.g., 20 ml in a syringe or 500 ml in a bag), but it is often omitted.\r\n\r\nEven a general dosing recommendation such as 'Use according to protocol' or 'See instructions for use' can be adequate. Then, no dose is specified.",
        "comment": "Note that this specifies the quantity of the specified medication, not the quantity for each active ingredient(s). Each ingredient amount can be communicated in the Medication resource. For example, if one wants to communicate that a tablet was 375 mg, where the dose was one tablet, you can use the Medication resource to document that the tablet was comprised of 375 mg of drug XYZ. Alternatively if the dose was 375 mg, then you may only need to use the Medication resource to indicate this was a tablet. If the example were an IV such as dopamine and you wanted to communicate that 400mg of dopamine was mixed in 500 ml of some IV solution, then this would all be communicated in the Medication resource. If the administration is not intended to be instantaneous (rate is present or timing has a duration), this can be specified to convey the total amount to be administered over the period of time as indicated by the schedule e.g. 500 ml in dose, with timing used to convey that this should be done over 4 hours.",
        "requirements": "The amount of therapeutic or other substance given at one administration event.",
        "alias": [
          "Keerdosis"
        ],
        "min": 0,
        "max": "1",
        "base": {
          "path": "Dosage.doseAndRate.dose[x]",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "Range"
          },
          {
            "code": "Quantity",
            "profile": [
              "http://hl7.org/fhir/StructureDefinition/SimpleQuantity"
            ]
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          }
        ],
        "isSummary": true,
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "v2",
            "map": "RXO-2, RXE-3"
          },
          {
            "identity": "rim",
            "map": ".doseQuantity"
          },
          {
            "identity": "zib-instructionsforuse-v1.2.1-2020EN",
            "map": "NL-CM:9.12.19940",
            "comment": "Dose [DEPRECATED]"
          },
          {
            "identity": "mp-dataset-mp9-300-rc2-20260213",
            "map": "mp-dataelement9x-316",
            "comment": "Dose"
          },
          {
            "identity": "mp-dataset-mp9-300-rc2-20260213",
            "map": "mp-dataelement9x-67",
            "comment": "Dose"
          },
          {
            "identity": "mp-dataset-mp9-300-rc2-20260213",
            "map": "mp-dataelement9x-384",
            "comment": "Dose"
          },
          {
            "identity": "mp-dataset-mp9-300-rc2-20260213",
            "map": "mp-dataelement9x-655",
            "comment": "Dose"
          }
        ]
      },
      {
        "id": "Dosage.doseAndRate.dose[x]:doseRange",
        "path": "Dosage.doseAndRate.dose[x]",
        "sliceName": "doseRange",
        "short": "Amount of medication per dose",
        "definition": "Amount of medication per dose.",
        "comment": "Note that this specifies the quantity of the specified medication, not the quantity for each active ingredient(s). Each ingredient amount can be communicated in the Medication resource. For example, if one wants to communicate that a tablet was 375 mg, where the dose was one tablet, you can use the Medication resource to document that the tablet was comprised of 375 mg of drug XYZ. Alternatively if the dose was 375 mg, then you may only need to use the Medication resource to indicate this was a tablet. If the example were an IV such as dopamine and you wanted to communicate that 400mg of dopamine was mixed in 500 ml of some IV solution, then this would all be communicated in the Medication resource. If the administration is not intended to be instantaneous (rate is present or timing has a duration), this can be specified to convey the total amount to be administered over the period of time as indicated by the schedule e.g. 500 ml in dose, with timing used to convey that this should be done over 4 hours.",
        "requirements": "The amount of therapeutic or other substance given at one administration event.",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Dosage.doseAndRate.dose[x]",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "Range"
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          }
        ],
        "isSummary": true,
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "v2",
            "map": "RXO-2, RXE-3"
          },
          {
            "identity": "rim",
            "map": ".doseQuantity"
          }
        ]
      },
      {
        "id": "Dosage.doseAndRate.dose[x]:doseRange.id",
        "path": "Dosage.doseAndRate.dose[x].id",
        "representation": [
          "xmlAttr"
        ],
        "short": "Unique id for inter-element referencing",
        "definition": "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Element.id",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
                "valueUrl": "string"
              }
            ],
            "code": "http://hl7.org/fhirpath/System.String"
          }
        ],
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          }
        ]
      },
      {
        "id": "Dosage.doseAndRate.dose[x]:doseRange.extension",
        "path": "Dosage.doseAndRate.dose[x].extension",
        "slicing": {
          "discriminator": [
            {
              "type": "value",
              "path": "url"
            }
          ],
          "description": "Extensions are always sliced by (at least) url",
          "rules": "open"
        },
        "short": "Additional content defined by implementations",
        "definition": "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance  applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.",
        "comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
        "alias": [
          "extensions",
          "user content"
        ],
        "min": 0,
        "max": "*",
        "base": {
          "path": "Element.extension",
          "min": 0,
          "max": "*"
        },
        "type": [
          {
            "code": "Extension"
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          },
          {
            "key": "ext-1",
            "severity": "error",
            "human": "Must have either extensions or value[x], not both",
            "expression": "extension.exists() != value.exists()",
            "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), 'value')])",
            "source": "http://hl7.org/fhir/StructureDefinition/Extension"
          }
        ],
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "rim",
            "map": "N/A"
          }
        ]
      },
      {
        "id": "Dosage.doseAndRate.dose[x]:doseRange.low",
        "path": "Dosage.doseAndRate.dose[x].low",
        "short": "minimumValue",
        "definition": "The minimal value of the range. The boundary is inclusive.",
        "comment": "The context of use may frequently define what kind of quantity this is and therefore what kind of units can be used. The context of use may also restrict the values for the comparator.",
        "alias": [
          "minimumWaarde"
        ],
        "min": 0,
        "max": "1",
        "base": {
          "path": "Range.low",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "Quantity",
            "profile": [
              "http://nictiz.nl/fhir/StructureDefinition/pattern-GstdSimpleQuantity"
            ]
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          },
          {
            "key": "qty-3",
            "severity": "error",
            "human": "If a code for the unit is present, the system SHALL also be present",
            "expression": "code.empty() or system.exists()",
            "xpath": "not(exists(f:code)) or exists(f:system)",
            "source": "http://hl7.org/fhir/StructureDefinition/Quantity"
          },
          {
            "key": "sqty-1",
            "severity": "error",
            "human": "The comparator is not used on a SimpleQuantity",
            "expression": "comparator.empty()",
            "xpath": "not(exists(f:comparator))",
            "source": "http://hl7.org/fhir/StructureDefinition/SimpleQuantity"
          }
        ],
        "isModifier": false,
        "isSummary": true,
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "v2",
            "map": "SN (see also Range) or CQ"
          },
          {
            "identity": "rim",
            "map": "PQ, IVL<PQ>, MO, CO, depending on the values"
          },
          {
            "identity": "v2",
            "map": "NR.1"
          },
          {
            "identity": "rim",
            "map": "./low"
          },
          {
            "identity": "zib-range-v1.0.1-2020EN",
            "map": "NL-CM:20.1.2",
            "comment": "minimumValue"
          }
        ]
      },
      {
        "id": "Dosage.doseAndRate.dose[x]:doseRange.high",
        "path": "Dosage.doseAndRate.dose[x].high",
        "short": "maximumValue",
        "definition": "The maximum value of the range. The boundary is inclusive.",
        "comment": "The context of use may frequently define what kind of quantity this is and therefore what kind of units can be used. The context of use may also restrict the values for the comparator.",
        "alias": [
          "maximumWaarde"
        ],
        "min": 0,
        "max": "1",
        "base": {
          "path": "Range.high",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "Quantity",
            "profile": [
              "http://nictiz.nl/fhir/StructureDefinition/pattern-GstdSimpleQuantity"
            ]
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          },
          {
            "key": "qty-3",
            "severity": "error",
            "human": "If a code for the unit is present, the system SHALL also be present",
            "expression": "code.empty() or system.exists()",
            "xpath": "not(exists(f:code)) or exists(f:system)",
            "source": "http://hl7.org/fhir/StructureDefinition/Quantity"
          },
          {
            "key": "sqty-1",
            "severity": "error",
            "human": "The comparator is not used on a SimpleQuantity",
            "expression": "comparator.empty()",
            "xpath": "not(exists(f:comparator))",
            "source": "http://hl7.org/fhir/StructureDefinition/SimpleQuantity"
          }
        ],
        "isModifier": false,
        "isSummary": true,
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "v2",
            "map": "SN (see also Range) or CQ"
          },
          {
            "identity": "rim",
            "map": "PQ, IVL<PQ>, MO, CO, depending on the values"
          },
          {
            "identity": "v2",
            "map": "NR.2"
          },
          {
            "identity": "rim",
            "map": "./high"
          },
          {
            "identity": "zib-range-v1.0.1-2020EN",
            "map": "NL-CM:20.1.3",
            "comment": "maximumValue"
          }
        ]
      },
      {
        "id": "Dosage.doseAndRate.dose[x]:doseQuantity",
        "path": "Dosage.doseAndRate.dose[x]",
        "sliceName": "doseQuantity",
        "short": "nominalValue",
        "definition": "Amount of medication per dose. The nominal value of the quantity.",
        "comment": "The context of use may frequently define what kind of quantity this is and therefore what kind of units can be used. The context of use may also restrict the values for the comparator.",
        "requirements": "The amount of therapeutic or other substance given at one administration event.",
        "alias": [
          "nominaleWaarde"
        ],
        "min": 0,
        "max": "1",
        "base": {
          "path": "Dosage.doseAndRate.dose[x]",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "Quantity",
            "profile": [
              "http://nictiz.nl/fhir/StructureDefinition/pattern-GstdSimpleQuantity"
            ]
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          },
          {
            "key": "qty-3",
            "severity": "error",
            "human": "If a code for the unit is present, the system SHALL also be present",
            "expression": "code.empty() or system.exists()",
            "xpath": "not(exists(f:code)) or exists(f:system)",
            "source": "http://hl7.org/fhir/StructureDefinition/Quantity"
          },
          {
            "key": "sqty-1",
            "severity": "error",
            "human": "The comparator is not used on a SimpleQuantity",
            "expression": "comparator.empty()",
            "xpath": "not(exists(f:comparator))",
            "source": "http://hl7.org/fhir/StructureDefinition/SimpleQuantity"
          }
        ],
        "isModifier": false,
        "isSummary": true,
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "v2",
            "map": "RXO-2, RXE-3"
          },
          {
            "identity": "rim",
            "map": ".doseQuantity"
          },
          {
            "identity": "v2",
            "map": "SN (see also Range) or CQ"
          },
          {
            "identity": "rim",
            "map": "PQ, IVL<PQ>, MO, CO, depending on the values"
          },
          {
            "identity": "zib-range-v1.0.1-2020EN",
            "map": "NL-CM:20.1.4",
            "comment": "nominalValue"
          }
        ]
      },
      {
        "id": "Dosage.doseAndRate.rate[x]",
        "path": "Dosage.doseAndRate.rate[x]",
        "slicing": {
          "discriminator": [
            {
              "type": "type",
              "path": "$this"
            }
          ],
          "rules": "open"
        },
        "short": "AdministeringSpeed",
        "definition": "The administering speed is used in slow administration of liquid. In practice, the measuring unit is almost always ml/hour, but can also be parametric with i.e. body weight or body surface area (in the case of a MedicationAgreement, VariableDosingRegimen or AdministrationAgreement). Entering an interval (such as 0-10 ml/hour) is also a commonly used option.\r\n\nFor example, with an administering speed of 10ml/hour:\r\n* value = 10\r\n* unit = ml/hour",
        "comment": "It is possible to supply both a rate and a doseQuantity to provide full details about how the medication is to be administered and supplied. If the rate is intended to change over time, depending on local rules/regulations, each change should be captured as a new version of the MedicationRequest with an updated rate, or captured with a new MedicationRequest with the new rate.\r\rIt is possible to specify a rate over time (for example, 100 ml/hour) using either the rateRatio and rateQuantity.  The rateQuantity approach requires systems to have the capability to parse UCUM grammer where ml/hour is included rather than a specific ratio where the time is specified as the denominator.  Where a rate such as 500ml over 2 hours is specified, the use of rateRatio may be more semantically correct than specifying using a rateQuantity of 250 mg/hour.",
        "requirements": "Identifies the speed with which the medication was or will be introduced into the patient. Typically the rate for an infusion e.g. 100 ml per 1 hour or 100 ml/hr.  May also be expressed as a rate per unit of time e.g. 500 ml per 2 hours.   Other examples: 200 mcg/min or 200 mcg/1 minute; 1 liter/8 hours.  Sometimes, a rate can imply duration when expressed as total volume / duration (e.g.  500mL/2 hours implies a duration of 2 hours).  However, when rate doesn't imply duration (e.g. 250mL/hour), then the timing.repeat.duration is needed to convey the infuse over time period.",
        "alias": [
          "Toedieningssnelheid"
        ],
        "min": 0,
        "max": "1",
        "base": {
          "path": "Dosage.doseAndRate.rate[x]",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "Ratio"
          },
          {
            "code": "Range"
          },
          {
            "code": "Quantity",
            "profile": [
              "http://hl7.org/fhir/StructureDefinition/SimpleQuantity"
            ]
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          }
        ],
        "isSummary": true,
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "v2",
            "map": "RXE22, RXE23, RXE-24"
          },
          {
            "identity": "rim",
            "map": ".rateQuantity"
          },
          {
            "identity": "zib-instructionsforuse-v1.2.1-2020EN",
            "map": "NL-CM:9.12.19942",
            "comment": "AdministeringSpeed"
          }
        ]
      },
      {
        "id": "Dosage.doseAndRate.rate[x]:rateRange",
        "path": "Dosage.doseAndRate.rate[x]",
        "sliceName": "rateRange",
        "short": "Amount of medication per unit of time",
        "definition": "Amount of medication per unit of time.",
        "comment": "It is possible to supply both a rate and a doseQuantity to provide full details about how the medication is to be administered and supplied. If the rate is intended to change over time, depending on local rules/regulations, each change should be captured as a new version of the MedicationRequest with an updated rate, or captured with a new MedicationRequest with the new rate.\r\rIt is possible to specify a rate over time (for example, 100 ml/hour) using either the rateRatio and rateQuantity.  The rateQuantity approach requires systems to have the capability to parse UCUM grammer where ml/hour is included rather than a specific ratio where the time is specified as the denominator.  Where a rate such as 500ml over 2 hours is specified, the use of rateRatio may be more semantically correct than specifying using a rateQuantity of 250 mg/hour.",
        "requirements": "Identifies the speed with which the medication was or will be introduced into the patient. Typically the rate for an infusion e.g. 100 ml per 1 hour or 100 ml/hr.  May also be expressed as a rate per unit of time e.g. 500 ml per 2 hours.   Other examples: 200 mcg/min or 200 mcg/1 minute; 1 liter/8 hours.  Sometimes, a rate can imply duration when expressed as total volume / duration (e.g.  500mL/2 hours implies a duration of 2 hours).  However, when rate doesn't imply duration (e.g. 250mL/hour), then the timing.repeat.duration is needed to convey the infuse over time period.",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Dosage.doseAndRate.rate[x]",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "Range"
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          }
        ],
        "isSummary": true,
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "v2",
            "map": "RXE22, RXE23, RXE-24"
          },
          {
            "identity": "rim",
            "map": ".rateQuantity"
          }
        ]
      },
      {
        "id": "Dosage.doseAndRate.rate[x]:rateRange.id",
        "path": "Dosage.doseAndRate.rate[x].id",
        "representation": [
          "xmlAttr"
        ],
        "short": "Unique id for inter-element referencing",
        "definition": "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Element.id",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
                "valueUrl": "string"
              }
            ],
            "code": "http://hl7.org/fhirpath/System.String"
          }
        ],
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          }
        ]
      },
      {
        "id": "Dosage.doseAndRate.rate[x]:rateRange.extension",
        "path": "Dosage.doseAndRate.rate[x].extension",
        "slicing": {
          "discriminator": [
            {
              "type": "value",
              "path": "url"
            }
          ],
          "description": "Extensions are always sliced by (at least) url",
          "rules": "open"
        },
        "short": "Additional content defined by implementations",
        "definition": "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance  applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.",
        "comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
        "alias": [
          "extensions",
          "user content"
        ],
        "min": 0,
        "max": "*",
        "base": {
          "path": "Element.extension",
          "min": 0,
          "max": "*"
        },
        "type": [
          {
            "code": "Extension"
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          },
          {
            "key": "ext-1",
            "severity": "error",
            "human": "Must have either extensions or value[x], not both",
            "expression": "extension.exists() != value.exists()",
            "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), 'value')])",
            "source": "http://hl7.org/fhir/StructureDefinition/Extension"
          }
        ],
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "rim",
            "map": "N/A"
          }
        ]
      },
      {
        "id": "Dosage.doseAndRate.rate[x]:rateRange.low",
        "path": "Dosage.doseAndRate.rate[x].low",
        "short": "minimumValue",
        "definition": "The minimal value of the range. The boundary is inclusive.",
        "comment": "If the low element is missing, the low boundary is not known.",
        "alias": [
          "minimumWaarde"
        ],
        "min": 0,
        "max": "1",
        "base": {
          "path": "Range.low",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "Quantity",
            "profile": [
              "http://hl7.org/fhir/StructureDefinition/SimpleQuantity"
            ]
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          },
          {
            "key": "qty-3",
            "severity": "error",
            "human": "If a code for the unit is present, the system SHALL also be present",
            "expression": "code.empty() or system.exists()",
            "xpath": "not(exists(f:code)) or exists(f:system)",
            "source": "http://hl7.org/fhir/StructureDefinition/Quantity"
          },
          {
            "key": "sqty-1",
            "severity": "error",
            "human": "The comparator is not used on a SimpleQuantity",
            "expression": "comparator.empty()",
            "xpath": "not(exists(f:comparator))",
            "source": "http://hl7.org/fhir/StructureDefinition/SimpleQuantity"
          }
        ],
        "isModifier": false,
        "isSummary": true,
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "v2",
            "map": "SN (see also Range) or CQ"
          },
          {
            "identity": "rim",
            "map": "PQ, IVL<PQ>, MO, CO, depending on the values"
          },
          {
            "identity": "v2",
            "map": "NR.1"
          },
          {
            "identity": "rim",
            "map": "./low"
          },
          {
            "identity": "zib-range-v1.0.1-2020EN",
            "map": "NL-CM:20.1.2",
            "comment": "minimumValue"
          }
        ]
      },
      {
        "id": "Dosage.doseAndRate.rate[x]:rateRange.high",
        "path": "Dosage.doseAndRate.rate[x].high",
        "short": "maximumValue",
        "definition": "The maximum value of the range. The boundary is inclusive.",
        "comment": "If the high element is missing, the high boundary is not known.",
        "alias": [
          "maximumWaarde"
        ],
        "min": 0,
        "max": "1",
        "base": {
          "path": "Range.high",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "Quantity",
            "profile": [
              "http://hl7.org/fhir/StructureDefinition/SimpleQuantity"
            ]
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          },
          {
            "key": "qty-3",
            "severity": "error",
            "human": "If a code for the unit is present, the system SHALL also be present",
            "expression": "code.empty() or system.exists()",
            "xpath": "not(exists(f:code)) or exists(f:system)",
            "source": "http://hl7.org/fhir/StructureDefinition/Quantity"
          },
          {
            "key": "sqty-1",
            "severity": "error",
            "human": "The comparator is not used on a SimpleQuantity",
            "expression": "comparator.empty()",
            "xpath": "not(exists(f:comparator))",
            "source": "http://hl7.org/fhir/StructureDefinition/SimpleQuantity"
          }
        ],
        "isModifier": false,
        "isSummary": true,
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "v2",
            "map": "SN (see also Range) or CQ"
          },
          {
            "identity": "rim",
            "map": "PQ, IVL<PQ>, MO, CO, depending on the values"
          },
          {
            "identity": "v2",
            "map": "NR.2"
          },
          {
            "identity": "rim",
            "map": "./high"
          },
          {
            "identity": "zib-range-v1.0.1-2020EN",
            "map": "NL-CM:20.1.3",
            "comment": "maximumValue"
          }
        ]
      },
      {
        "id": "Dosage.doseAndRate.rate[x]:rateQuantity",
        "path": "Dosage.doseAndRate.rate[x]",
        "sliceName": "rateQuantity",
        "short": "nominalValue",
        "definition": "The nominal value of the quantity.",
        "comment": "It is possible to supply both a rate and a doseQuantity to provide full details about how the medication is to be administered and supplied. If the rate is intended to change over time, depending on local rules/regulations, each change should be captured as a new version of the MedicationRequest with an updated rate, or captured with a new MedicationRequest with the new rate.\r\rIt is possible to specify a rate over time (for example, 100 ml/hour) using either the rateRatio and rateQuantity.  The rateQuantity approach requires systems to have the capability to parse UCUM grammer where ml/hour is included rather than a specific ratio where the time is specified as the denominator.  Where a rate such as 500ml over 2 hours is specified, the use of rateRatio may be more semantically correct than specifying using a rateQuantity of 250 mg/hour.",
        "requirements": "Identifies the speed with which the medication was or will be introduced into the patient. Typically the rate for an infusion e.g. 100 ml per 1 hour or 100 ml/hr.  May also be expressed as a rate per unit of time e.g. 500 ml per 2 hours.   Other examples: 200 mcg/min or 200 mcg/1 minute; 1 liter/8 hours.  Sometimes, a rate can imply duration when expressed as total volume / duration (e.g.  500mL/2 hours implies a duration of 2 hours).  However, when rate doesn't imply duration (e.g. 250mL/hour), then the timing.repeat.duration is needed to convey the infuse over time period.",
        "alias": [
          "nominaleWaarde"
        ],
        "min": 0,
        "max": "1",
        "base": {
          "path": "Dosage.doseAndRate.rate[x]",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "Quantity",
            "profile": [
              "http://hl7.org/fhir/StructureDefinition/SimpleQuantity"
            ]
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          }
        ],
        "isSummary": true,
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "v2",
            "map": "RXE22, RXE23, RXE-24"
          },
          {
            "identity": "rim",
            "map": ".rateQuantity"
          },
          {
            "identity": "zib-range-v1.0.1-2020EN",
            "map": "NL-CM:20.1.4",
            "comment": "nominalValue"
          }
        ]
      },
      {
        "id": "Dosage.maxDosePerPeriod",
        "path": "Dosage.maxDosePerPeriod",
        "short": "MaximumDose",
        "definition": "A maximum dose maximizes (in time) the usage of a drug in an 'as needed' prescription.",
        "comment": "This is intended for use as an adjunct to the dosage when there is an upper cap.  For example \"2 tablets every 4 hours to a maximum of 8/day\".",
        "requirements": "The maximum total quantity of a therapeutic substance that may be administered to a subject over the period of time.  For example, 1000mg in 24 hours.",
        "alias": [
          "MaximaleDosering"
        ],
        "min": 0,
        "max": "1",
        "base": {
          "path": "Dosage.maxDosePerPeriod",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "Ratio"
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          },
          {
            "key": "rat-1",
            "severity": "error",
            "human": "Numerator and denominator SHALL both be present, or both are absent. If both are absent, there SHALL be some extension present",
            "expression": "(numerator.empty() xor denominator.exists()) and (numerator.exists() or extension.exists())",
            "xpath": "(count(f:numerator) = count(f:denominator)) and ((count(f:numerator) > 0) or (count(f:extension) > 0))",
            "source": "http://hl7.org/fhir/StructureDefinition/Ratio"
          }
        ],
        "isSummary": true,
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "v2",
            "map": "N/A"
          },
          {
            "identity": "rim",
            "map": "RTO"
          },
          {
            "identity": "v2",
            "map": "RXO-23, RXE-19"
          },
          {
            "identity": "rim",
            "map": ".maxDoseQuantity"
          },
          {
            "identity": "zib-instructionsforuse-v1.2.1-2020EN",
            "map": "NL-CM:9.12.19946",
            "comment": "MaximumDose"
          }
        ]
      },
      {
        "id": "Dosage.maxDosePerPeriod.id",
        "path": "Dosage.maxDosePerPeriod.id",
        "representation": [
          "xmlAttr"
        ],
        "short": "Unique id for inter-element referencing",
        "definition": "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Element.id",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
                "valueUrl": "string"
              }
            ],
            "code": "http://hl7.org/fhirpath/System.String"
          }
        ],
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          }
        ]
      },
      {
        "id": "Dosage.maxDosePerPeriod.extension",
        "path": "Dosage.maxDosePerPeriod.extension",
        "slicing": {
          "discriminator": [
            {
              "type": "value",
              "path": "url"
            }
          ],
          "description": "Extensions are always sliced by (at least) url",
          "rules": "open"
        },
        "short": "Additional content defined by implementations",
        "definition": "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance  applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.",
        "comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
        "alias": [
          "extensions",
          "user content"
        ],
        "min": 0,
        "max": "*",
        "base": {
          "path": "Element.extension",
          "min": 0,
          "max": "*"
        },
        "type": [
          {
            "code": "Extension"
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          },
          {
            "key": "ext-1",
            "severity": "error",
            "human": "Must have either extensions or value[x], not both",
            "expression": "extension.exists() != value.exists()",
            "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), 'value')])",
            "source": "http://hl7.org/fhir/StructureDefinition/Extension"
          }
        ],
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "rim",
            "map": "N/A"
          }
        ]
      },
      {
        "id": "Dosage.maxDosePerPeriod.numerator",
        "path": "Dosage.maxDosePerPeriod.numerator",
        "short": "A fixed quantity (no comparator)",
        "definition": "The comparator is not used on a SimpleQuantity",
        "comment": "The context of use may frequently define what kind of quantity this is and therefore what kind of units can be used. The context of use may also restrict the values for the comparator.",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Ratio.numerator",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "Quantity",
            "profile": [
              "http://nictiz.nl/fhir/StructureDefinition/pattern-GstdSimpleQuantity"
            ]
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          },
          {
            "key": "qty-3",
            "severity": "error",
            "human": "If a code for the unit is present, the system SHALL also be present",
            "expression": "code.empty() or system.exists()",
            "xpath": "not(exists(f:code)) or exists(f:system)",
            "source": "http://hl7.org/fhir/StructureDefinition/Quantity"
          },
          {
            "key": "sqty-1",
            "severity": "error",
            "human": "The comparator is not used on a SimpleQuantity",
            "expression": "comparator.empty()",
            "xpath": "not(exists(f:comparator))",
            "source": "http://hl7.org/fhir/StructureDefinition/SimpleQuantity"
          }
        ],
        "isModifier": false,
        "isSummary": true,
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "v2",
            "map": "SN (see also Range) or CQ"
          },
          {
            "identity": "rim",
            "map": "PQ, IVL<PQ>, MO, CO, depending on the values"
          },
          {
            "identity": "rim",
            "map": ".numerator"
          }
        ]
      },
      {
        "id": "Dosage.maxDosePerPeriod.denominator",
        "path": "Dosage.maxDosePerPeriod.denominator",
        "short": "A fixed quantity (no comparator)",
        "definition": "The comparator is not used on a SimpleQuantity",
        "comment": "The context of use may frequently define what kind of quantity this is and therefore what kind of units can be used. The context of use may also restrict the values for the comparator.",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Ratio.denominator",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "Quantity",
            "profile": [
              "http://nictiz.nl/fhir/StructureDefinition/pattern-GstdSimpleQuantity"
            ]
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          },
          {
            "key": "qty-3",
            "severity": "error",
            "human": "If a code for the unit is present, the system SHALL also be present",
            "expression": "code.empty() or system.exists()",
            "xpath": "not(exists(f:code)) or exists(f:system)",
            "source": "http://hl7.org/fhir/StructureDefinition/Quantity"
          },
          {
            "key": "sqty-1",
            "severity": "error",
            "human": "The comparator is not used on a SimpleQuantity",
            "expression": "comparator.empty()",
            "xpath": "not(exists(f:comparator))",
            "source": "http://hl7.org/fhir/StructureDefinition/SimpleQuantity"
          }
        ],
        "isModifier": false,
        "isSummary": true,
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "v2",
            "map": "SN (see also Range) or CQ"
          },
          {
            "identity": "rim",
            "map": "PQ, IVL<PQ>, MO, CO, depending on the values"
          },
          {
            "identity": "rim",
            "map": ".denominator"
          }
        ]
      },
      {
        "id": "Dosage.maxDosePerAdministration",
        "path": "Dosage.maxDosePerAdministration",
        "short": "Upper limit on medication per administration",
        "definition": "Upper limit on medication per administration.",
        "comment": "This is intended for use as an adjunct to the dosage when there is an upper cap.  For example, a body surface area related dose with a maximum amount, such as 1.5 mg/m2 (maximum 2 mg) IV over 5 – 10 minutes would have doseQuantity of 1.5 mg/m2 and maxDosePerAdministration of 2 mg.",
        "requirements": "The maximum total quantity of a therapeutic substance that may be administered to a subject per administration.",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Dosage.maxDosePerAdministration",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "Quantity",
            "profile": [
              "http://hl7.org/fhir/StructureDefinition/SimpleQuantity"
            ]
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          },
          {
            "key": "qty-3",
            "severity": "error",
            "human": "If a code for the unit is present, the system SHALL also be present",
            "expression": "code.empty() or system.exists()",
            "xpath": "not(exists(f:code)) or exists(f:system)",
            "source": "http://hl7.org/fhir/StructureDefinition/Quantity"
          },
          {
            "key": "sqty-1",
            "severity": "error",
            "human": "The comparator is not used on a SimpleQuantity",
            "expression": "comparator.empty()",
            "xpath": "not(exists(f:comparator))",
            "source": "http://hl7.org/fhir/StructureDefinition/SimpleQuantity"
          }
        ],
        "isModifier": false,
        "isSummary": true,
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "v2",
            "map": "SN (see also Range) or CQ"
          },
          {
            "identity": "rim",
            "map": "PQ, IVL<PQ>, MO, CO, depending on the values"
          },
          {
            "identity": "rim",
            "map": "not supported"
          }
        ]
      },
      {
        "id": "Dosage.maxDosePerLifetime",
        "path": "Dosage.maxDosePerLifetime",
        "short": "Upper limit on medication per lifetime of the patient",
        "definition": "Upper limit on medication per lifetime of the patient.",
        "comment": "The context of use may frequently define what kind of quantity this is and therefore what kind of units can be used. The context of use may also restrict the values for the comparator.",
        "requirements": "The maximum total quantity of a therapeutic substance that may be administered per lifetime of the subject.",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Dosage.maxDosePerLifetime",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "Quantity",
            "profile": [
              "http://hl7.org/fhir/StructureDefinition/SimpleQuantity"
            ]
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          },
          {
            "key": "qty-3",
            "severity": "error",
            "human": "If a code for the unit is present, the system SHALL also be present",
            "expression": "code.empty() or system.exists()",
            "xpath": "not(exists(f:code)) or exists(f:system)",
            "source": "http://hl7.org/fhir/StructureDefinition/Quantity"
          },
          {
            "key": "sqty-1",
            "severity": "error",
            "human": "The comparator is not used on a SimpleQuantity",
            "expression": "comparator.empty()",
            "xpath": "not(exists(f:comparator))",
            "source": "http://hl7.org/fhir/StructureDefinition/SimpleQuantity"
          }
        ],
        "isModifier": false,
        "isSummary": true,
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "v2",
            "map": "SN (see also Range) or CQ"
          },
          {
            "identity": "rim",
            "map": "PQ, IVL<PQ>, MO, CO, depending on the values"
          },
          {
            "identity": "rim",
            "map": "not supported"
          }
        ]
      }
    ]
  },
  "differential": {
    "element": [
      {
        "id": "Dosage",
        "path": "Dosage",
        "short": "DosingInstructions",
        "definition": "Indicates how the medication is/was taken or should be taken by the patient. Instructions for the administrator to administer the medication (the patient themselves, a nurse or other aid). When taking stock of medication use, the dosage describes the pattern of use established by the patient.",
        "comment": "This element _mostly_ represents the DosingInstructions container from zib InstructionsForUse, but also includes the AdditionalInstructions and RouteOfAdministration concepts, which are normally placed on the same level as this container. As a result, these concepts are **duplicated** in every repetition of this element, even though these concepts should be present just once according to the zib.\r\n\r\nThis element does not contain a mapping to the Dosage container from zib InstructionsForUse. However, all child concepts of the Dosage concept are mapped. If an instance of zib container DosingInstructions contains multiple Dosage containers, each of these results in a separate instance of the FHIR Dosage data type conforming to this profile, wherein `.sequence` (zib concept SequenceNumber) and `.timing.repeat.bounds[x]:boundsDuration` (zib concept DoseDuration) are equal.",
        "alias": [
          "Doseerinstructie"
        ],
        "mapping": [
          {
            "identity": "zib-instructionsforuse-v1.2.1-2020EN",
            "map": "NL-CM:9.12.22095",
            "comment": "DosingInstructions"
          }
        ]
      },
      {
        "id": "Dosage.extension:asNeeded",
        "path": "Dosage.extension",
        "sliceName": "asNeeded",
        "type": [
          {
            "code": "Extension",
            "profile": [
              "http://nictiz.nl/fhir/StructureDefinition/ext-Dosage-AsNeededFor"
            ]
          }
        ]
      },
      {
        "id": "Dosage.extension:asNeeded.value[x]",
        "path": "Dosage.extension.value[x]",
        "short": "Condition",
        "definition": "The condition for administering medication can be:\r\n\r\n* a physiological measurement value (plasma glucose concentration, body temperature, blood pressure);\r\n* a symptom or other circumstance (in the event of a headache, or itch).\r\n\r\nSupplemental information from G-standard bst362 make up the list of values for coded entering of this concept. Also always include the textual description of that code. Physiological measurement values or other conditions that do not occur in bst362 do not need to be coded. These can be expressed in free text in the Description concept.",
        "alias": [
          "Criterium"
        ],
        "binding": {
          "strength": "required",
          "valueSet": "http://decor.nictiz.nl/fhir/ValueSet/2.16.840.1.113883.2.4.3.11.60.40.2.9.12.4--20200901000000"
        },
        "mapping": [
          {
            "identity": "zib-instructionsforuse-v1.2.1-2020EN",
            "map": "NL-CM:9.12.19945",
            "comment": "Condition"
          }
        ]
      },
      {
        "id": "Dosage.sequence",
        "path": "Dosage.sequence",
        "short": "SequenceNumber",
        "definition": "This indicates the sequence of the dosing instructions within the medication agreement.",
        "alias": [
          "Volgnummer"
        ],
        "mapping": [
          {
            "identity": "zib-instructionsforuse-v1.2.1-2020EN",
            "map": "NL-CM:9.12.22503",
            "comment": "SequenceNumber"
          }
        ]
      },
      {
        "id": "Dosage.additionalInstruction",
        "path": "Dosage.additionalInstruction",
        "short": "AdditionalInstructions",
        "definition": "The additional instructions contain extra information on the use of the current prescription. The additional instructions applies to the entire instructions for use and not to an individual dosage.\r\n\r\nThis includes all instructions for use. The text can come from the original “paper\" medication prescription, but can also be generated from the coded information.\r\n\r\nThe instructions may not conflict with other components of the medication agreement/ administration agreement.\r\n\r\nThe instructions can also refer to an existing protocol. In the case of an external dosing regimen (e.g., \"according to thrombosis service regimen\"), OTH is used.\r\n\r\nThe texts in the G-standard that can support this attribute are included in table 362 where the texts from the general practitioner' standard 'NHG-Tabel 25-component b: 'aanvullende teksten’ ' are included. These texts can only be used when it is not possible to include this information in the other structured elements of the Instructions for Use.\r\n\r\nA free-text explanation of the Instructions for Use can be placed under code OTH if it is not possible to record it in a structured manner within the Instructions for Use.",
        "comment": "Please note that in contrast to the zib, this AdditionalInstructions concept is grouped under the DosingInstructions concept. This `.additionalInstruction` element shall have the same value when there are multiple DosingInstructions.",
        "alias": [
          "AanvullendeInstructie"
        ],
        "binding": {
          "strength": "required",
          "description": "WCIAv3 Tabel 25 B-codes subset voor aanvullende gebruiksinstructies",
          "valueSet": "http://decor.nictiz.nl/fhir/ValueSet/2.16.840.1.113883.2.4.3.11.60.20.77.11.9--20160407000000"
        },
        "mapping": [
          {
            "identity": "mp-dataset-mp9-300-rc1-20250522",
            "map": "mp-dataelement9x-51",
            "comment": "AdditionalInstructions"
          },
          {
            "identity": "mp-dataset-mp9-300-rc2-20260213",
            "map": "mp-dataelement9x-51",
            "comment": "AdditionalInstructions"
          },
          {
            "identity": "mp-dataset-mp9-300-rc1-20250522",
            "map": "mp-dataelement9x-649",
            "comment": "AdditionalInstructions"
          },
          {
            "identity": "mp-dataset-mp9-300-rc2-20260213",
            "map": "mp-dataelement9x-649",
            "comment": "AdditionalInstructions"
          },
          {
            "identity": "mp-dataset-mp9-300-rc1-20250522",
            "map": "mp-dataelement9x-300",
            "comment": "AdditionalInstructions"
          },
          {
            "identity": "mp-dataset-mp9-300-rc2-20260213",
            "map": "mp-dataelement9x-300",
            "comment": "AdditionalInstructions"
          },
          {
            "identity": "mp-dataset-mp9-300-rc1-20250522",
            "map": "mp-dataelement9x-368",
            "comment": "AdditionalInstructions"
          },
          {
            "identity": "mp-dataset-mp9-300-rc2-20260213",
            "map": "mp-dataelement9x-368",
            "comment": "AdditionalInstructions"
          }
        ]
      },
      {
        "id": "Dosage.timing",
        "path": "Dosage.timing",
        "short": "AdministeringSchedule",
        "definition": "Specifications of the times at which the medication is to be administered. This is indicated as follows:\r\n* Time(s) (16:00) or indications (“before meals”) at which the medication is to be taken each day.\r\n* A specific number of times the medication is to be taken each day (\"3x a day\"), indicated with the frequency.\r\n* A time interval between consecutive doses (“Every 2 hours”, “every 3 days”), indicated with the word Interval.\r\n* Combined periods with an interval and duration (“1 daily for three out of four weeks: the pill schedule”)\r\n\r\nIf a certain medication is not to be taken daily, the aforementioned can be combined with daily indications:\r\n\r\n* One or more week days on which the medication is to be administered (e.g. “Monday, Wednesday, Friday”)\r\n* ”3x a week”, “2x a month”.\r\n\r\nThe specified administration “infinite” is automatically to be repeated until:\r\n* The end date and time has been reached\r\n* The total administration duration has been reached (14 days)\r\n* A specific amount of administrations has been reached (“20 doses”), to be entered in the Frequency concept.",
        "alias": [
          "Toedieningsschema"
        ],
        "mapping": [
          {
            "identity": "zib-instructionsforuse-v1.2.1-2020EN",
            "map": "NL-CM:9.12.19948",
            "comment": "AdministeringSchedule"
          }
        ]
      },
      {
        "id": "Dosage.timing.repeat.extension:timingExact",
        "path": "Dosage.timing.repeat.extension",
        "sliceName": "timingExact",
        "type": [
          {
            "code": "Extension",
            "profile": [
              "http://hl7.org/fhir/StructureDefinition/timing-exact"
            ]
          }
        ]
      },
      {
        "id": "Dosage.timing.repeat.extension:timingExact.value[x]",
        "path": "Dosage.timing.repeat.extension.value[x]",
        "definition": "Indicates that the timing as specified by `.frequency`, `.period` and `.periodUnit` should be strictly interpreted. This is the case when the zib concept Interval is expressed using these elements (as opposed to the zib concept Frequency).\r\n\r\nThe times can be chosen freely, but distribution throughout the day is more precise, and the interval between times is important (e.g. in the case of antibiotics). In the case of Baxter packs and intramural care, such a prescription is used to draw up a (location-specific) outline for distribution times (logistics).",
        "comment": "Notes on the zib concepts Frequency and Interval:\n1. An interval (in FHIR) is just a normal frequency of 1 (combined with a period based on the interval length) and is represented in FHIR as just another frequency using `.frequency` (set to 1), `.period` and `.periodUnit`. However, the zib differentiates between the two concepts in the timing precision (the Interval concept defines precise intervals while the Frequency concept defines approximate intervals). When the interval is precise, this is communicated using the extension in `.extension:timingExact`.\n2. On the other hand, the zib Frequency concept might be used to express a single-use, non-repeating series by omitting the time unit. In FHIR, this is _not_ represented as a frequency, but with the `.count` element.\n3. Lastly, the Frequency concept may be used to express either a single nominal value or a range. A range is represented by respectively setting the minimum and maximum value to `.frequency` and `.frequencyMax`, or to `.count` and `.countMax` for single-use events. A nominal value is expressed by setting its value to `.frequency` or to `.count` for single-use events, and leaving `.frequencyMax` and `.countMax` unpopulated.\n\nIn summary:\n* zib concept Frequency:\n    * With time unit:\n        * Nominal value: `.frequency`, `.period` and `.periodUnit`\n        * Range: `.frequency`, `.frequencyMax`, `.period` and `.periodUnit`\n    * Without time unit:\n        * Nominal value: `.count`\n        * Range: `.count` and `.countMax`\n* zib concept Interval: `.frequency` (set to 1), `.period`, `.periodUnit` and `.extension:timingExact` (set to _true_)",
        "mapping": [
          {
            "identity": "zib-instructionsforuse-v1.2.1-2020EN",
            "map": "NL-CM:9.12.19950",
            "comment": "Interval (implicit, main mapping is on `.frequency`, `.period` and `.periodMax`)"
          },
          {
            "identity": "mp-dataset-mp9-300-rc1-20250522",
            "map": "mp-dataelement9x-271",
            "comment": "(negative of) IsFlexible"
          },
          {
            "identity": "mp-dataset-mp9-300-rc2-20260213",
            "map": "mp-dataelement9x-271",
            "comment": "(negative of) IsFlexible"
          },
          {
            "identity": "mp-dataset-mp9-300-rc1-20250522",
            "map": "mp-dataelement9x-672",
            "comment": "(negative of) IsFlexible"
          },
          {
            "identity": "mp-dataset-mp9-300-rc2-20260213",
            "map": "mp-dataelement9x-672",
            "comment": "(negative of) IsFlexible"
          },
          {
            "identity": "mp-dataset-mp9-300-rc1-20250522",
            "map": "mp-dataelement9x-580",
            "comment": "(negative of) IsFlexible"
          },
          {
            "identity": "mp-dataset-mp9-300-rc2-20260213",
            "map": "mp-dataelement9x-580",
            "comment": "(negative of) IsFlexible"
          },
          {
            "identity": "mp-dataset-mp9-300-rc1-20250522",
            "map": "mp-dataelement9x-412",
            "comment": "(negative of) IsFlexible"
          },
          {
            "identity": "mp-dataset-mp9-300-rc2-20260213",
            "map": "mp-dataelement9x-412",
            "comment": "(negative of) IsFlexible"
          }
        ]
      },
      {
        "id": "Dosage.timing.repeat.bounds[x]",
        "path": "Dosage.timing.repeat.bounds[x]",
        "slicing": {
          "discriminator": [
            {
              "type": "type",
              "path": "$this"
            }
          ],
          "rules": "open"
        }
      },
      {
        "id": "Dosage.timing.repeat.bounds[x]:boundsDuration",
        "path": "Dosage.timing.repeat.bounds[x]",
        "sliceName": "boundsDuration",
        "short": "DoseDuration",
        "definition": "The intended time duration for these dosing instructions, e.g. 5 days or 8 weeks. \r\nIn the case of medication for an indefinite period, the dosing duration is left empty in the last dosing instruction.",
        "alias": [
          "Doseerduur"
        ],
        "type": [
          {
            "code": "Duration"
          }
        ],
        "mapping": [
          {
            "identity": "zib-instructionsforuse-v1.2.1-2020EN",
            "map": "NL-CM:9.12.22506",
            "comment": "DoseDuration"
          }
        ]
      },
      {
        "id": "Dosage.timing.repeat.count",
        "path": "Dosage.timing.repeat.count",
        "short": "Frequency / minimumValue / nominalValue",
        "definition": "Usually, frequency comprises both amount and time unit (3 times a day), but it can occur without the time unit (single use). This is represented by this `.count` element and optionally `.countMax` if a range should be represented.",
        "comment": "Notes on the zib concept Frequency can be found in the comment of the `.frequency` element.",
        "alias": [
          "Frequentie",
          "nominaleWaarde",
          "minimumWaarde"
        ],
        "mapping": [
          {
            "identity": "zib-instructionsforuse-v1.2.1-2020EN",
            "map": "NL-CM:9.12.19949",
            "comment": "Frequency (single use only)"
          },
          {
            "identity": "zib-range-v1.0.1-2020EN",
            "map": "NL-CM:20.1.2",
            "comment": "minimumValue"
          },
          {
            "identity": "zib-range-v1.0.1-2020EN",
            "map": "NL-CM:20.1.4",
            "comment": "nominalValue"
          }
        ]
      },
      {
        "id": "Dosage.timing.repeat.countMax",
        "path": "Dosage.timing.repeat.countMax",
        "short": "Frequency / maximumValue",
        "definition": "Usually, frequency comprises both amount and time unit (3 times a day), but it can occur without the time unit (single use). This is represented by the `.count` element and optionally `.countMax` if a range should be represented.",
        "comment": "Notes on the zib concept Frequency can be found in the comment of the `.frequency` element.",
        "alias": [
          "Frequentie",
          "maximumWaarde"
        ],
        "mapping": [
          {
            "identity": "zib-instructionsforuse-v1.2.1-2020EN",
            "map": "NL-CM:9.12.19949",
            "comment": "Frequency"
          },
          {
            "identity": "zib-range-v1.0.1-2020EN",
            "map": "NL-CM:20.1.3",
            "comment": "maximumValue"
          }
        ]
      },
      {
        "id": "Dosage.timing.repeat.duration",
        "path": "Dosage.timing.repeat.duration",
        "short": "DurationOfAdministration",
        "definition": "The duration of administration defines the length of time during which the drug is administered and is mainly used in the slow parenteral administration of fluids. The `durationUnit` defines the time unit.",
        "alias": [
          "Toedieningsduur"
        ],
        "mapping": [
          {
            "identity": "zib-instructionsforuse-v1.2.1-2020EN",
            "map": "NL-CM:9.12.23141",
            "comment": "DurationOfAdministration"
          }
        ]
      },
      {
        "id": "Dosage.timing.repeat.durationUnit",
        "path": "Dosage.timing.repeat.durationUnit",
        "short": "DurationOfAdministration",
        "definition": "The units of time, in UCUM units, for the duration of administration of time during which the drug is administered.",
        "alias": [
          "Toedieningsduur"
        ],
        "mapping": [
          {
            "identity": "zib-instructionsforuse-v1.2.1-2020EN",
            "map": "NL-CM:9.12.23141",
            "comment": "DurationOfAdministration"
          }
        ]
      },
      {
        "id": "Dosage.timing.repeat.frequency",
        "path": "Dosage.timing.repeat.frequency",
        "short": "Frequency / minimumValue / nominalValue / Interval",
        "definition": "The `.frequency` element indicates either the number of dose moments per time unit (zib concept Frequency) or the time between dose times (zib concept Interval).\r\n\r\nIf `.frequencyMax` is present, this `.frequency`  element indicates the lower bound of the allowed range of the frequency.",
        "comment": "Notes on the zib concepts Frequency and Interval, The zib differentiates between the two concepts in the specific usage of the extension `.extension:timingExact` and the element `.timeOfDay` combined:\n1. The zib Interval (in FHIR) is just a normal frequency of 1 (combined with a period based on the interval length) and is represented in FHIR as just another frequency using `.frequency` (set to 1), `.period`, `.periodUnit`, the extension `.extension:timingExact` set to _true_ and the absence of the element `.timeOfDay`.\n2. The zib Frequency concept might be used to express a single-use, non-repeating series by omitting the time unit. In FHIR, this is _not_ represented as a frequency, but with the `.count` element.\n3. Lastly, the Frequency concept may be used to express either a single nominal value or a range. The extension `.extension:timingExact` can be used to specify the precision of the timing of the administration (i.e. the element `.timeOfDay`). When this element is meant to convey the zib Frequency concept this can be, unlike the zib concept Interval, either _true_or _false_. A range is represented by respectively setting the minimum and maximum value to `.frequency` and `.frequencyMax`, or to `.count` and `.countMax` for single-use events as mentioned in the second point. A nominal value is expressed by setting its value to `.frequency` or to `.count` for single-use events, and leaving `.frequencyMax` and `.countMax` unpopulated.\n\nIn summary:\n* zib concept Frequency:\n    * With time unit (precision of the timing can be further specified with the extension `.extension:timingExact`):\n        * Nominal value: `.frequency`, `.period` and `.periodUnit`\n        * Range: `.frequency`, `.frequencyMax`, `.period` and `.periodUnit`\n    * Without time unit:\n        * Nominal value: `.count`\n        * Range: `.count` and `.countMax`\n* zib concept Interval: `.frequency` (set to 1), `.period`, `.periodUnit`, `.extension:timingExact` (SHALL be set to _true_) and the absence of `.timeOfDay`.",
        "alias": [
          "Frequentie",
          "minimumWaarde",
          "nominaleWaarde",
          "Interval"
        ],
        "mapping": [
          {
            "identity": "zib-instructionsforuse-v1.2.1-2020EN",
            "map": "NL-CM:9.12.19949",
            "comment": "Frequency"
          },
          {
            "identity": "zib-range-v1.0.1-2020EN",
            "map": "NL-CM:20.1.2",
            "comment": "minimumValue"
          },
          {
            "identity": "zib-range-v1.0.1-2020EN",
            "map": "NL-CM:20.1.4",
            "comment": "nominalValue"
          },
          {
            "identity": "zib-instructionsforuse-v1.2.1-2020EN",
            "map": "NL-CM:9.12.19950",
            "comment": "Interval"
          }
        ]
      },
      {
        "id": "Dosage.timing.repeat.frequencyMax",
        "path": "Dosage.timing.repeat.frequencyMax",
        "short": "Frequency / maximumValue",
        "comment": "Notes on the zib concept Frequency can be found in the comment of the `.frequency` element.",
        "alias": [
          "maximumWaarde",
          "Frequentie"
        ],
        "mapping": [
          {
            "identity": "zib-instructionsforuse-v1.2.1-2020EN",
            "map": "NL-CM:9.12.19949",
            "comment": "Frequency"
          },
          {
            "identity": "zib-range-v1.0.1-2020EN",
            "map": "NL-CM:20.1.3",
            "comment": "maximumValue"
          }
        ]
      },
      {
        "id": "Dosage.timing.repeat.period",
        "path": "Dosage.timing.repeat.period",
        "short": "Frequency / Interval",
        "definition": "Indicates the duration of time over which repetitions are to occur; e.g. to express \"3 times per day\", 3 would be the frequency and \"1 day\" would be the period. If `.periodMax` is present, this element indicates the lower bound of the allowed range of the period length.",
        "comment": "Notes on the zib concepts Frequency and Interval can be found in the comment of the `.frequency` element.",
        "alias": [
          "Frequentie",
          "Interval"
        ],
        "mapping": [
          {
            "identity": "zib-instructionsforuse-v1.2.1-2020EN",
            "map": "NL-CM:9.12.19949",
            "comment": "Frequency"
          },
          {
            "identity": "zib-instructionsforuse-v1.2.1-2020EN",
            "map": "NL-CM:9.12.19950",
            "comment": "Interval"
          }
        ]
      },
      {
        "id": "Dosage.timing.repeat.periodUnit",
        "path": "Dosage.timing.repeat.periodUnit",
        "short": "Frequency / Interval",
        "definition": "The units of time for the period in UCUM units for Frequency and Interval.",
        "comment": "Notes on the zib concepts Frequency and Interval can be found in the comment of the `.frequency` element.",
        "alias": [
          "Frequentie",
          "Interval"
        ],
        "mapping": [
          {
            "identity": "zib-instructionsforuse-v1.2.1-2020EN",
            "map": "NL-CM:9.12.19949",
            "comment": "Frequency. When frequency is used, set `.extension.timingExact` to false."
          },
          {
            "identity": "zib-instructionsforuse-v1.2.1-2020EN",
            "map": "NL-CM:9.12.19950",
            "comment": "Interval"
          }
        ]
      },
      {
        "id": "Dosage.timing.repeat.dayOfWeek",
        "path": "Dosage.timing.repeat.dayOfWeek",
        "short": "WeekDay",
        "definition": "WeekDay indicates a pattern of doses on fixed week days.",
        "comment": "If no days are specified, the action is assumed to happen every day as otherwise specified.",
        "alias": [
          "Weekdag"
        ],
        "binding": {
          "strength": "required",
          "description": "Use ConceptMap 'WeekdagCodelijst_to_DaysOfWeek' to translate zib terminology to profile terminology in ValueSet 'DaysOfWeek'",
          "valueSet": "http://hl7.org/fhir/ValueSet/days-of-week|4.0.1",
          "_valueSet": {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/11179-permitted-value-conceptmap",
                "valueCanonical": "http://nictiz.nl/fhir/ConceptMap/WeekdagCodelijst-to-DaysOfWeek"
              }
            ]
          }
        },
        "mapping": [
          {
            "identity": "zib-instructionsforuse-v1.2.1-2020EN",
            "map": "NL-CM:9.12.19952",
            "comment": "WeekDay"
          }
        ]
      },
      {
        "id": "Dosage.timing.repeat.timeOfDay",
        "path": "Dosage.timing.repeat.timeOfDay",
        "short": "AdministrationTime",
        "definition": "The time of administration is a specific time of day (on the clock). This time usually isn’t (intended to be) exact. There can be multiple administering times in one day. \r\n\r\nThe ideal time of administration can also be entered as a time of day (morning, afternoon, evening, night-time). The administration time is then to be left empty, and the time of day can be entered in the TimeOfDay concept.",
        "comment": "If there's a `.timeOfDay`, there cannot be a `.when`, or vice versa.",
        "alias": [
          "Toedientijd"
        ],
        "mapping": [
          {
            "identity": "zib-instructionsforuse-v1.2.1-2020EN",
            "map": "NL-CM:9.12.19951",
            "comment": "AdministrationTime"
          }
        ]
      },
      {
        "id": "Dosage.timing.repeat.when",
        "path": "Dosage.timing.repeat.when",
        "short": "TimeOfDay",
        "definition": "Time of day: morning, afternoon, evening, night.",
        "comment": "If there's a `.timeOfDay`, there cannot be a `.when`, or vice versa.",
        "alias": [
          "Dagdeel"
        ],
        "binding": {
          "strength": "required",
          "description": "Use ConceptMap 'DagdeelCodelijst_to_EventTiming' to translate zib terminology to profile terminology in ValueSet 'EventTiming'",
          "valueSet": "http://hl7.org/fhir/ValueSet/event-timing",
          "_valueSet": {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/11179-permitted-value-conceptmap",
                "valueCanonical": "http://nictiz.nl/fhir/ConceptMap/DagdeelCodelijst-to-EventTiming"
              }
            ]
          }
        },
        "mapping": [
          {
            "identity": "zib-instructionsforuse-v1.2.1-2020EN",
            "map": "NL-CM:9.12.19953",
            "comment": "TimeOfDay"
          }
        ]
      },
      {
        "id": "Dosage.asNeeded[x]",
        "path": "Dosage.asNeeded[x]",
        "slicing": {
          "discriminator": [
            {
              "type": "type",
              "path": "$this"
            }
          ],
          "rules": "open"
        }
      },
      {
        "id": "Dosage.asNeeded[x]:asNeededCodeableConcept",
        "path": "Dosage.asNeeded[x]",
        "sliceName": "asNeededCodeableConcept",
        "short": "Condition",
        "definition": "Condition for administration of medication can be:\r\n\r\n*a measured physiological value (plasma glucose level, body temperature, blood pressure);\r\n*a symptom or other condition (headache, itching).\r\n\r\nRelevant “as needed” conditions from NHG Table 25 form the value list for transmitting this concept in coded form. The conditions supported in the G-standard are included in file 362. The textual description of that code must always be provided as well.\r\n\r\nPhysiological measurements or other conditions that are not included in the “as needed” conditions of NHG Table 25 can be expressed in free text using the OTH code.",
        "comment": "If only one 'asNeeded' concept is exchanged within a Dosage, use Dosage.asNeeded[x]. Otherwise use the extension Dosage.extension:asNeeded.value[x] for when multiple 'asNeeded' concepts are to be exchanged.\r\n\r\nCan express \"as needed\" without a reason by setting the Boolean = True.  In this case the CodeableConcept is not populated.  Or you can express \"as needed\" with a reason by including the CodeableConcept.  In this case the Boolean is assumed to be True.  If you set the Boolean to False, then the dose is given according to the schedule and is not \"prn\" or \"as needed\".",
        "alias": [
          "Criterium"
        ],
        "type": [
          {
            "code": "CodeableConcept"
          }
        ],
        "binding": {
          "strength": "required",
          "valueSet": "http://decor.nictiz.nl/fhir/ValueSet/2.16.840.1.113883.2.4.3.11.60.40.2.9.12.4--20200901000000"
        },
        "mapping": [
          {
            "identity": "zib-instructionsforuse-v1.2.1-2020EN",
            "map": "NL-CM:9.12.19945",
            "comment": "Condition [DEPRECATED]"
          },
          {
            "identity": "mp-dataset-mp9-300-rc2-20260213",
            "map": "mp-dataelement9x-321",
            "comment": "Condition"
          },
          {
            "identity": "mp-dataset-mp9-300-rc2-20260213",
            "map": "mp-dataelement9x-72",
            "comment": "Condition"
          },
          {
            "identity": "mp-dataset-mp9-300-rc2-20260213",
            "map": "mp-dataelement9x-389",
            "comment": "Condition"
          },
          {
            "identity": "mp-dataset-mp9-300-rc2-20260213",
            "map": "mp-dataelement9x-676",
            "comment": "Condition"
          }
        ]
      },
      {
        "id": "Dosage.asNeeded[x]:asNeededCodeableConcept.text",
        "path": "Dosage.asNeeded[x].text",
        "mapping": [
          {
            "identity": "mp-dataset-mp9-300-rc1-20250522",
            "map": "mp-dataelement9x-272",
            "comment": "Description"
          },
          {
            "identity": "mp-dataset-mp9-300-rc2-20260213",
            "map": "mp-dataelement9x-272",
            "comment": "Description"
          },
          {
            "identity": "mp-dataset-mp9-300-rc1-20250522",
            "map": "mp-dataelement9x-677",
            "comment": "Description"
          },
          {
            "identity": "mp-dataset-mp9-300-rc2-20260213",
            "map": "mp-dataelement9x-677",
            "comment": "Description"
          },
          {
            "identity": "mp-dataset-mp9-300-rc1-20250522",
            "map": "mp-dataelement9x-582",
            "comment": "Description"
          },
          {
            "identity": "mp-dataset-mp9-300-rc2-20260213",
            "map": "mp-dataelement9x-582",
            "comment": "Description"
          },
          {
            "identity": "mp-dataset-mp9-300-rc1-20250522",
            "map": "mp-dataelement9x-514",
            "comment": "Description"
          },
          {
            "identity": "mp-dataset-mp9-300-rc2-20260213",
            "map": "mp-dataelement9x-514",
            "comment": "Description"
          }
        ]
      },
      {
        "id": "Dosage.route",
        "path": "Dosage.route",
        "short": "RouteOfAdministration",
        "definition": "The route through which the medication is administered (oral, nasal, intravenous, etc.). The routes of administration supported in the G-standard are included in file 902, thesaurus number 7.",
        "comment": "Please note that in contrast to the zib, this RouteOfAdministration concept is grouped under the DosingInstructions concept. This `.route` element shall have the same value when there are multiple DosingInstructions.",
        "alias": [
          "Toedieningsweg"
        ],
        "binding": {
          "strength": "required",
          "valueSet": "http://decor.nictiz.nl/fhir/ValueSet/2.16.840.1.113883.2.4.3.11.60.40.2.9.12.1--20200901000000"
        },
        "mapping": [
          {
            "identity": "zib-instructionsforuse-v1.2.1-2020EN",
            "map": "NL-CM:9.12.19941",
            "comment": "RouteOfAdministration [DEPRECATED]"
          },
          {
            "identity": "mp-dataset-mp9-300-rc2-20260213",
            "map": "mp-dataelement9x-303",
            "comment": "RouteOfAdministration"
          },
          {
            "identity": "mp-dataset-mp9-300-rc2-20260213",
            "map": "mp-dataelement9x-430",
            "comment": "RouteOfAdministration"
          },
          {
            "identity": "mp-dataset-mp9-300-rc2-20260213",
            "map": "mp-dataelement9x-54",
            "comment": "RouteOfAdministration"
          },
          {
            "identity": "mp-dataset-mp9-300-rc2-20260213",
            "map": "mp-dataelement9x-371",
            "comment": "RouteOfAdministration"
          },
          {
            "identity": "mp-dataset-mp9-300-rc2-20260213",
            "map": "mp-dataelement9x-648",
            "comment": "RouteOfAdministration"
          }
        ]
      },
      {
        "id": "Dosage.doseAndRate.dose[x]",
        "path": "Dosage.doseAndRate.dose[x]",
        "slicing": {
          "discriminator": [
            {
              "type": "type",
              "path": "$this"
            }
          ],
          "rules": "open"
        },
        "short": "Dose",
        "definition": "The dose indicates the amount/unit per administration. The unit can be any unit that can occur with this particular medicine. For liquids and other divisible products, a volume measure (preferably \"ml\") will usually be used.\r\n\r\nIn many cases, the prescriber may want to specify the dosage in units of weight of the active substance.\r\n\r\nIf only the substance is indicated and not the product, then the amount of that substance is specified. For example, Paracetamol 1000 mg is equivalent to Paracetamol 500 mg tablets, 2 tablets (or units).\r\n\r\nThe dosage is sometimes indicated in a calculation, which often uses the patient's body weight or body surface area as a parameter. However, the calculation remains nothing more than a tool to aid decision-making.\r\n\r\nIn continuous administration, alongside the administration speed, the dose can be specified (e.g., 20 ml in a syringe or 500 ml in a bag), but it is often omitted.\r\n\r\nEven a general dosing recommendation such as 'Use according to protocol' or 'See instructions for use' can be adequate. Then, no dose is specified.",
        "alias": [
          "Keerdosis"
        ],
        "mapping": [
          {
            "identity": "zib-instructionsforuse-v1.2.1-2020EN",
            "map": "NL-CM:9.12.19940",
            "comment": "Dose [DEPRECATED]"
          },
          {
            "identity": "mp-dataset-mp9-300-rc2-20260213",
            "map": "mp-dataelement9x-316",
            "comment": "Dose"
          },
          {
            "identity": "mp-dataset-mp9-300-rc2-20260213",
            "map": "mp-dataelement9x-67",
            "comment": "Dose"
          },
          {
            "identity": "mp-dataset-mp9-300-rc2-20260213",
            "map": "mp-dataelement9x-384",
            "comment": "Dose"
          },
          {
            "identity": "mp-dataset-mp9-300-rc2-20260213",
            "map": "mp-dataelement9x-655",
            "comment": "Dose"
          }
        ]
      },
      {
        "id": "Dosage.doseAndRate.dose[x]:doseRange",
        "path": "Dosage.doseAndRate.dose[x]",
        "sliceName": "doseRange",
        "type": [
          {
            "code": "Range"
          }
        ]
      },
      {
        "id": "Dosage.doseAndRate.dose[x]:doseRange.low",
        "path": "Dosage.doseAndRate.dose[x].low",
        "short": "minimumValue",
        "definition": "The minimal value of the range. The boundary is inclusive.",
        "alias": [
          "minimumWaarde"
        ],
        "type": [
          {
            "code": "Quantity",
            "profile": [
              "http://nictiz.nl/fhir/StructureDefinition/pattern-GstdSimpleQuantity"
            ]
          }
        ],
        "mapping": [
          {
            "identity": "zib-range-v1.0.1-2020EN",
            "map": "NL-CM:20.1.2",
            "comment": "minimumValue"
          }
        ]
      },
      {
        "id": "Dosage.doseAndRate.dose[x]:doseRange.high",
        "path": "Dosage.doseAndRate.dose[x].high",
        "short": "maximumValue",
        "definition": "The maximum value of the range. The boundary is inclusive.",
        "alias": [
          "maximumWaarde"
        ],
        "type": [
          {
            "code": "Quantity",
            "profile": [
              "http://nictiz.nl/fhir/StructureDefinition/pattern-GstdSimpleQuantity"
            ]
          }
        ],
        "mapping": [
          {
            "identity": "zib-range-v1.0.1-2020EN",
            "map": "NL-CM:20.1.3",
            "comment": "maximumValue"
          }
        ]
      },
      {
        "id": "Dosage.doseAndRate.dose[x]:doseQuantity",
        "path": "Dosage.doseAndRate.dose[x]",
        "sliceName": "doseQuantity",
        "short": "nominalValue",
        "definition": "Amount of medication per dose. The nominal value of the quantity.",
        "alias": [
          "nominaleWaarde"
        ],
        "type": [
          {
            "code": "Quantity",
            "profile": [
              "http://nictiz.nl/fhir/StructureDefinition/pattern-GstdSimpleQuantity"
            ]
          }
        ],
        "mapping": [
          {
            "identity": "zib-range-v1.0.1-2020EN",
            "map": "NL-CM:20.1.4",
            "comment": "nominalValue"
          }
        ]
      },
      {
        "id": "Dosage.doseAndRate.rate[x]",
        "path": "Dosage.doseAndRate.rate[x]",
        "slicing": {
          "discriminator": [
            {
              "type": "type",
              "path": "$this"
            }
          ],
          "rules": "open"
        },
        "short": "AdministeringSpeed",
        "definition": "The administering speed is used in slow administration of liquid. In practice, the measuring unit is almost always ml/hour, but can also be parametric with i.e. body weight or body surface area (in the case of a MedicationAgreement, VariableDosingRegimen or AdministrationAgreement). Entering an interval (such as 0-10 ml/hour) is also a commonly used option.\r\n\nFor example, with an administering speed of 10ml/hour:\r\n* value = 10\r\n* unit = ml/hour",
        "alias": [
          "Toedieningssnelheid"
        ],
        "mapping": [
          {
            "identity": "zib-instructionsforuse-v1.2.1-2020EN",
            "map": "NL-CM:9.12.19942",
            "comment": "AdministeringSpeed"
          }
        ]
      },
      {
        "id": "Dosage.doseAndRate.rate[x]:rateRange",
        "path": "Dosage.doseAndRate.rate[x]",
        "sliceName": "rateRange",
        "type": [
          {
            "code": "Range"
          }
        ]
      },
      {
        "id": "Dosage.doseAndRate.rate[x]:rateRange.low",
        "path": "Dosage.doseAndRate.rate[x].low",
        "short": "minimumValue",
        "definition": "The minimal value of the range. The boundary is inclusive.",
        "alias": [
          "minimumWaarde"
        ],
        "mapping": [
          {
            "identity": "zib-range-v1.0.1-2020EN",
            "map": "NL-CM:20.1.2",
            "comment": "minimumValue"
          }
        ]
      },
      {
        "id": "Dosage.doseAndRate.rate[x]:rateRange.high",
        "path": "Dosage.doseAndRate.rate[x].high",
        "short": "maximumValue",
        "definition": "The maximum value of the range. The boundary is inclusive.",
        "alias": [
          "maximumWaarde"
        ],
        "mapping": [
          {
            "identity": "zib-range-v1.0.1-2020EN",
            "map": "NL-CM:20.1.3",
            "comment": "maximumValue"
          }
        ]
      },
      {
        "id": "Dosage.doseAndRate.rate[x]:rateQuantity",
        "path": "Dosage.doseAndRate.rate[x]",
        "sliceName": "rateQuantity",
        "short": "nominalValue",
        "definition": "The nominal value of the quantity.",
        "alias": [
          "nominaleWaarde"
        ],
        "type": [
          {
            "code": "Quantity"
          }
        ],
        "mapping": [
          {
            "identity": "zib-range-v1.0.1-2020EN",
            "map": "NL-CM:20.1.4",
            "comment": "nominalValue"
          }
        ]
      },
      {
        "id": "Dosage.maxDosePerPeriod",
        "path": "Dosage.maxDosePerPeriod",
        "short": "MaximumDose",
        "definition": "A maximum dose maximizes (in time) the usage of a drug in an 'as needed' prescription.",
        "alias": [
          "MaximaleDosering"
        ],
        "mapping": [
          {
            "identity": "zib-instructionsforuse-v1.2.1-2020EN",
            "map": "NL-CM:9.12.19946",
            "comment": "MaximumDose"
          }
        ]
      },
      {
        "id": "Dosage.maxDosePerPeriod.numerator",
        "path": "Dosage.maxDosePerPeriod.numerator",
        "type": [
          {
            "code": "Quantity",
            "profile": [
              "http://nictiz.nl/fhir/StructureDefinition/pattern-GstdSimpleQuantity"
            ]
          }
        ]
      },
      {
        "id": "Dosage.maxDosePerPeriod.denominator",
        "path": "Dosage.maxDosePerPeriod.denominator",
        "type": [
          {
            "code": "Quantity",
            "profile": [
              "http://nictiz.nl/fhir/StructureDefinition/pattern-GstdSimpleQuantity"
            ]
          }
        ]
      }
    ]
  }
}