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Source1

{
  "resourceType": "AllergyIntolerance",
  "id": "reac-pat09-rea-col-01",
  "meta": {
    "profile": [
      "http://nictiz.nl/fhir/StructureDefinition/cio-Reaction"
    ]
  },
  "extension": [
    {
      "url": "http://nictiz.nl/fhir/5.0/StructureDefinition/extension-AllergyIntolerance.type",
      "valueCodeableConcept": {
        "coding": [
          {
            "system": "http://snomed.info/sct",
            "code": "281647001",
            "display": "ongewenste reactie"
          }
        ]
      }
    },
    {
      "url": "http://hl7.org/fhir/StructureDefinition/allergyintolerance-assertedDate",
      "valueDateTime": "${DATE, T, D, -28}"
    },
    {
      "url": "http://nictiz.nl/fhir/StructureDefinition/ext-RelationCondition",
      "valueReference": {
        "reference": "Condition/aog-pat09-aog-re-col-01",
        "type": "Condition",
        "display": "Aandoening, startdatum: T-28D, einddatum: T-27D"
      }
    },
    {
      "url": "http://nictiz.nl/fhir/StructureDefinition/ext-Reaction.RelationHypersensitivityIntolerance",
      "valueReference": {
        "reference": "AllergyIntolerance/ovint-pat09-oi-peg-01",
        "type": "AllergyIntolerance",
        "display": "Overgevoeligheid/intolerantie, MACROGOL, diagnosedatum: T-7D{16:43:06}"
      }
    },
    {
      "url": "http://nictiz.nl/fhir/StructureDefinition/ext-MedicationHypersensitivity.Identifier",
      "valueIdentifier": {
        "system": "urn:oid:2.16.840.1.113883.2.4.3.11.999.26.1.341",
        "value": "pat09-gmo-01"
      }
    }
  ],
  "identifier": [
    {
      "system": "urn:oid:2.16.840.1.113883.2.4.3.11.999.26.1.4",
      "value": "pat09-rea-col-01"
    }
  ],
  "code": {
    "coding": [
      {
        "system": "urn:oid:2.16.840.1.113883.2.4.4.7",
        "code": "1504797",
        "display": "COLOFORT POEDER VOOR DRANK IN SACHET"
      }
    ]
  },
  "patient": {
    "reference": "Patient/patient-XXX-Hali",
    "type": "Patient",
    "display": "Patient, Abdelhak (Abdel) XXX_Hali"
  },
  "recordedDate": "${DATE, T, D, -7}T16:43:06+02:00",
  "recorder": {
    "reference": "PractitionerRole/pracrole-000003334",
    "type": "PractitionerRole",
    "display": "Healthcare professional (role), A. Rast, MEDISCH SPECIALIST, ALLERGOLOGIE, Algemeen Stadsziekenhuis"
  },
  "asserter": {
    "reference": "PractitionerRole/pracrole-000003334",
    "type": "PractitionerRole",
    "display": "Healthcare professional (role), A. Rast, MEDISCH SPECIALIST, ALLERGOLOGIE, Algemeen Stadsziekenhuis"
  },
  "reaction": [
    {
      "extension": [
        {
          "url": "http://nictiz.nl/fhir/StructureDefinition/ext-Reaction.LatencyTime",
          "valueQuantity": {
            "value": 5,
            "unit": "min",
            "system": "http://unitsofmeasure.org",
            "code": "min"
          }
        }
      ],
      "substance": {
        "coding": [
          {
            "system": "urn:oid:2.16.840.1.113883.2.4.4.7",
            "code": "1504797",
            "display": "COLOFORT POEDER VOOR DRANK IN SACHET"
          }
        ]
      },
      "onset": "${DATE, T, D, -28}",
      "exposureRoute": {
        "coding": [
          {
            "system": "urn:oid:2.16.840.1.113883.2.4.4.9",
            "code": "9",
            "display": "ORAAL"
          }
        ]
      },
      "note": [
        {
          "text": "Patiënt krijgt ter voorbereiding op een coloscopie Colofort. Enkele minuten na inname ontwikkelt de patiënt urticaria over het gehele lichaam, hypotensie en dyspnoe. Partner belt een ambulance, deze geven adrenaline en clemastine. In het ziekenhuis wordt patiënt behandeld met dexamethason en nogmaals clemastine."
        }
      ]
    }
  ]
}