FHIR IG analytics| Package | incisive.fhir |
| Resource Type | Bundle |
| Id | FHIRmessage_ProstateCancer_2023-07-25.json |
| FHIR Version | R4 |
No resources found
No resources found
No narrative content found in resource
FHIR
FHIRsmith{
"resourceType": "Bundle",
"identifier": {
"value": "Prostate Cancer INCISIVE"
},
"type": "transaction",
"timestamp": "2023-07-24T12:29:17.239+02:00",
"entry": [
{
"resource": {
"resourceType": "MessageHeader",
"eventCoding": {
"system": "http://snomed.org",
"code": "399068003",
"display": "Malignant tumor of prostate (disorder)"
},
"destination": [
{
"name": "example",
"endpoint": "https://exemple.com/services?wsdl"
}
],
"sender": {
"reference": "Organization/organization01",
"type": "Organization"
},
"source": {
"name": "example",
"contact": {
"system": "email",
"value": "example@example.en"
},
"endpoint": "https://example.en/origin"
},
"focus": [
{
"reference": "Patient/patient01",
"type": "Patient"
}
]
},
"request": {
"method": "POST",
"url": "MessageHeader"
}
},
{
"resource": {
"resourceType": "Organization",
"id": "organization01",
"meta": {
"profile": [
"https://simplifier.net/INCISIVE/StructureDefinition/OrganizationINCISIVE"
]
},
"identifier": [
{
"type": {
"coding": [
{
"system": "https://simplifier.net/INCISIVE/CodeSystem/INCISIVEDataProviders",
"code": "001",
"display": "AUTH"
}
]
}
}
],
"name": "Aristotle university of Thessaloniki"
},
"request": {
"method": "POST",
"url": "Organization"
}
},
{
"resource": {
"resourceType": "Medication",
"id": "medication01",
"code": {
"coding": [
{
"system": "http://snomed.org",
"code": "373873005",
"display": "Pharmaceutical / biologic product (product)"
}
],
"text": "Medication therapy"
},
"status": "active"
},
"request": {
"method": "POST",
"url": "Medication"
}
},
{
"resource": {
"resourceType": "Patient",
"id": "patient01",
"meta": {
"profile": [
"https://simplifier.net/INCISIVE/StructureDefinition/PatientINCISIVE"
]
},
"extension": [
{
"url": "https://simplifier.net/INCISIVE/StructureDefinition/CurrentState",
"valueCode": "0"
},
{
"url": "https://simplifier.net/INCISIVE/StructureDefinition/Ethnicity",
"valueCodeableConcept": {
"coding": [
{
"system": "https://simplifier.net/INCISIVE/CodeSystem/EthnicityOfPatient",
"code": "1",
"display": "White"
}
]
}
}
],
"identifier": [
{
"type": {
"text": "Pseudo-anonimized Identifier"
},
"value": "004-000001"
}
],
"managingOrganization": {
"reference": "Organization/organization01"
}
},
"request": {
"method": "POST",
"url": "Patient"
}
},
{
"resource": {
"resourceType": "Condition",
"id": "condition01",
"meta": {
"profile": [
"https://simplifier.net/INCISIVE/StructureDefinition/ConditionForBreastColorectalProstate"
]
},
"code": {
"coding": [
{
"system": "http://snomed.info/sct",
"code": "417662000",
"display": "History of clinical finding in subject (situation)"
}
],
"text": "MG30.10"
},
"subject": {
"reference": "Patient/patient01"
},
"evidence": [
{
"code": [
{
"coding": [
{
"system": "https://simplifier.net/INCISIVE/CodeSystem/ProstateSymptomsGeneralInfo",
"code": "1",
"display": "Difficulty starting urination"
}
]
}
]
}
]
},
"request": {
"method": "POST",
"url": "Condition"
}
},
{
"resource": {
"resourceType": "Condition",
"id": "condition02",
"meta": {
"profile": [
"https://simplifier.net/INCISIVE/StructureDefinition/ConditionForBreastColorectalProstate"
]
},
"code": {
"coding": [
{
"system": "http://snomed.info/sct",
"code": "404684003",
"display": "Clinical finding (finding)"
}
]
},
"subject": {
"reference": "Patient/patient01"
},
"note": [
{
"text": "Dysuria"
}
]
},
"request": {
"method": "POST",
"url": "Condition"
}
},
{
"resource": {
"resourceType": "Observation",
"id": "observation01",
"meta": {
"profile": [
"https://simplifier.net/INCISIVE/StructureDefinition/ObservationForProstate"
]
},
"status": "final",
"code": {
"coding": [
{
"system": "http://snomed.org",
"code": "399068003",
"display": "Malignant tumor of prostate (disorder)"
}
]
},
"subject": {
"reference": "Patient/patient01",
"type": "Patient"
},
"component": [
{
"code": {
"coding": [
{
"system": "http://snomed.org",
"code": "414205003",
"display": "Family history of prostate cancer (situation)"
}
]
},
"valueBoolean": true
},
{
"code": {
"coding": [
{
"system": "http://snomed.org",
"code": "275937001:408732007=66839005",
"display": "|Family history of cancer (situation)|:|Subject relationship context (attribute)|=|Father (person)|"
}
]
},
"valueBoolean": true
},
{
"code": {
"coding": [
{
"system": "http://snomed.org",
"code": "275937001:408732007=72705000",
"display": "|Family history of cancer (situation)|:|Subject relationship context (attribute)|=|Mother (person)|"
}
]
},
"valueBoolean": true
}
]
},
"request": {
"method": "POST",
"url": "Observation"
}
},
{
"resource": {
"resourceType": "DiagnosticReport",
"id": "diagnosticReport01",
"meta": {
"profile": [
"https://simplifier.net/INCISIVE/StructureDefinition/DiagnosticReportINCISIVE"
]
},
"extension": [
{
"url": "https://simplifier.net/INCISIVE/StructureDefinition/AgeAtDiagnosis",
"valueAge": {
"value": 56
}
}
],
"status": "final",
"code": {
"coding": [
{
"system": "http://snomed.org",
"code": "399068003",
"display": "Malignant tumor of prostate (disorder)"
}
]
},
"subject": {
"reference": "Patient/patient01"
},
"result": [
{
"reference": "Observation/observation01"
}
]
},
"request": {
"method": "POST",
"url": "DiagnosticReport"
}
},
{
"resource": {
"resourceType": "Observation",
"id": "observation02",
"meta": {
"profile": [
"https://simplifier.net/INCISIVE/StructureDefinition/ObservationForProstate"
]
},
"status": "final",
"code": {
"coding": [
{
"system": "http://snomed.org",
"code": "399068003",
"display": "Malignant tumor of prostate (disorder)"
}
]
},
"subject": {
"reference": "Patient/patient01",
"type": "Patient"
},
"bodySite": {
"coding": [
{
"system": "https://simplifier.net/INCISIVE/CodeSystem/ProstateLocalizationOfPIRADS",
"code": "3",
"display": "pZp apex"
}
]
},
"component": [
{
"code": {
"coding": [
{
"system": "http://snomed.org",
"code": "77477000",
"display": "Computed tomography (procedure)"
}
],
"text": "CT.dcm-path"
},
"valueBoolean": true
},
{
"code": {
"coding": [
{
"system": "http://snomed.org",
"code": "118247008:418775008=77477000",
"display": "|Radiologic finding (finding)|:|Finding method (attribute)|=|Computed tomography (procedure)|"
}
],
"text": "Annotated CT.dcm-path"
},
"valueCodeableConcept": {
"coding": [
{
"system": "https://simplifier.net/INCISIVE/CodeSystem/ProstateAnnotatedDicomFiles",
"code": "1",
"display": "Positive annotation"
}
]
}
},
{
"code": {
"coding": [
{
"system": "http://snomed.org",
"code": "82918005",
"display": "Positron emission tomography (procedure)"
}
],
"text": "PET/CT.dcm-path"
},
"valueBoolean": true
},
{
"code": {
"coding": [
{
"system": "http://snomed.org",
"code": "118247008:418775008=77477000",
"display": "|Radiologic finding (finding)|:|Finding method (attribute)|=|Computed tomography (procedure)|"
}
],
"text": "Annotated PET/CT.dcm-path"
},
"valueCodeableConcept": {
"coding": [
{
"system": "https://simplifier.net/INCISIVE/CodeSystem/ProstateAnnotatedDicomFiles",
"code": "1",
"display": "Positive annotation"
}
]
}
},
{
"code": {
"coding": [
{
"system": "http://snomed.org",
"code": "113091000",
"display": "Magnetic resonance imaging (procedure)"
}
],
"text": "MRI.dcm-path"
},
"valueBoolean": true
},
{
"code": {
"coding": [
{
"system": "http://snomed.org",
"code": "365853002:418775008=113091000",
"display": "|Imaging finding (finding)|:|Finding method (attribute)|=|Magnetic resonance imaging (procedure)|"
}
],
"text": "Annotated MRI.dcm-path"
},
"valueCodeableConcept": {
"coding": [
{
"system": "https://simplifier.net/INCISIVE/CodeSystem/ProstateAnnotatedDicomFiles",
"code": "1",
"display": "Positive annotation"
}
]
}
},
{
"code": {
"coding": [
{
"system": "http://snomed.org",
"code": "113091000:370130000=410656007",
"display": "|Magnetic resonance imaging (procedure)|:|Property (attribute)|=|Type (property) (qualifier value)|"
}
]
},
"valueCodeableConcept": {
"coding": [
{
"system": "https://simplifier.net/INCISIVE/CodeSystem/ProstateMRITypeBaseline",
"code": "0",
"display": "Prior biopsy"
}
]
}
},
{
"code": {
"coding": [
{
"system": "http://snomed.org",
"code": "228084000",
"display": "Whole body bone imaging (procedure)"
}
],
"text": "Bone Scintigraphy Scan.dcm-path"
},
"valueBoolean": true
},
{
"code": {
"coding": [
{
"system": "http://snomed.org",
"code": "118247008:418775008=228084000",
"display": "|Radiologic finding (finding)|:|Finding method (attribute)|=|Whole body bone imaging (procedure)|"
}
],
"text": "Annotated Bone Scintigraphy Scan.dcm-path"
},
"valueCodeableConcept": {
"coding": [
{
"system": "https://simplifier.net/INCISIVE/CodeSystem/ProstateAnnotatedDicomFiles",
"code": "1",
"display": "Positive annotation"
}
]
}
},
{
"code": {
"coding": [
{
"system": "http://snomed.org",
"code": "252416005",
"display": "Histopathology test (procedure)"
}
],
"text": "Histopathology Image.dcm-path"
},
"valueBoolean": true
},
{
"code": {
"coding": [
{
"system": "http://snomed.org",
"code": "250537006",
"display": "Histopathology finding (finding)"
}
],
"text": "Annotated Histopathology Image.dcm-path"
},
"valueCodeableConcept": {
"coding": [
{
"system": "https://simplifier.net/INCISIVE/CodeSystem/ProstateAnnotatedDicomFiles",
"code": "1",
"display": "Positive annotation"
}
]
}
},
{
"code": {
"coding": [
{
"system": "http://snomed.org",
"code": "363680008",
"display": "Radiographic imaging procedure (procedure)"
}
],
"text": "Xray.dcm-path"
},
"valueBoolean": true
},
{
"code": {
"coding": [
{
"system": "http://snomed.org",
"code": "118247008:418775008=168537006",
"display": "|Radiologic finding (finding)|:|Finding method (attribute)|=|Plain radiography (procedure)|"
}
],
"text": "Annotated Xray.dcm-path"
},
"valueCodeableConcept": {
"coding": [
{
"system": "https://simplifier.net/INCISIVE/CodeSystem/ProstateAnnotatedDicomFiles",
"code": "1",
"display": "Positive annotation"
}
]
}
},
{
"code": {
"coding": [
{
"system": "http://loinc.org",
"code": "15326-2",
"display": "Prostate Adenoma Volume by derived from height, width and length (US)"
}
]
},
"valueQuantity": {
"value": 2,
"unit": "cubic millimetre",
"system": "http://unitsofmeasure.org",
"code": "mm^3"
}
},
{
"code": {
"coding": [
{
"system": "http://snomed.org",
"code": "371480007",
"display": "Anatomic location of neoplasm (observable entity)"
}
]
},
"valueCodeableConcept": {
"coding": [
{
"system": "https://simplifier.net/INCISIVE/CodeSystem/ProstateSideOfTumor",
"code": "0",
"display": "Right"
}
]
}
},
{
"code": {
"coding": [
{
"system": "http://snomed.org",
"code": "254292007",
"display": "Tumor staging (tumor staging)"
}
]
},
"valueCodeableConcept": {
"coding": [
{
"system": "https://simplifier.net/INCISIVE/CodeSystem/ProstateMaximumPIRADS",
"code": "1",
"display": "PIRADS 1"
}
]
}
},
{
"code": {
"coding": [
{
"system": "http://snomed.org",
"code": "372306004",
"display": "Extraprostatic extension of tumor present (finding)"
}
]
},
"valueBoolean": true
},
{
"code": {
"coding": [
{
"system": "http://snomed.org",
"code": "372294007",
"display": "Seminal vesicle invasion by tumor present (finding)"
}
]
},
"valueBoolean": true
},
{
"code": {
"coding": [
{
"system": "http://loinc.org",
"code": "2857-1",
"display": "Prostate specific Ag [Mass/volume] in Serum or Plasma"
}
]
},
"valueQuantity": {
"value": 4.48,
"unit": "nanogram per millliiter",
"system": "http://unitsofmeasure.org",
"code": "ng/mL"
}
},
{
"code": {
"coding": [
{
"system": "http://snomed.org",
"code": "399504009",
"display": "cT category (observable entity)"
}
]
},
"valueCodeableConcept": {
"coding": [
{
"system": "https://simplifier.net/INCISIVE/CodeSystem/ProstateCT",
"code": "1",
"display": "cT1"
}
]
}
},
{
"code": {
"coding": [
{
"system": "http://snomed.org",
"code": "399534004",
"display": "cN category (observable entity)"
}
]
},
"valueCodeableConcept": {
"coding": [
{
"system": "https://simplifier.net/INCISIVE/CodeSystem/ProstateCN",
"code": "1",
"display": "N1"
}
]
}
},
{
"code": {
"coding": [
{
"system": "http://snomed.org",
"code": "399387003",
"display": "cM category (observable entity)"
}
]
},
"valueCodeableConcept": {
"coding": [
{
"system": "https://simplifier.net/INCISIVE/CodeSystem/ProstateCM",
"code": "1",
"display": "M1"
}
]
}
}
]
},
"request": {
"method": "POST",
"url": "Observation"
}
},
{
"resource": {
"resourceType": "Observation",
"id": "observation03",
"meta": {
"profile": [
"https://simplifier.net/INCISIVE/StructureDefinition/ObservationForProstate"
]
},
"status": "final",
"code": {
"coding": [
{
"system": "http://snomed.org",
"code": "399068003",
"display": "Malignant tumor of prostate (disorder)"
}
]
},
"subject": {
"reference": "Patient/patient01",
"type": "Patient"
},
"valueInteger": 2,
"component": [
{
"code": {
"coding": [
{
"system": "http://loinc.org",
"code": "2857-1",
"display": "Prostate specific Ag [Mass/volume] in Serum or Plasma"
}
]
},
"valueQuantity": {
"value": 4.26,
"unit": "nanogram per millliiter",
"system": "http://unitsofmeasure.org",
"code": "ng/mL"
}
}
]
},
"request": {
"method": "POST",
"url": "Observation"
}
},
{
"resource": {
"resourceType": "Observation",
"id": "observation04",
"meta": {
"profile": [
"https://simplifier.net/INCISIVE/StructureDefinition/ObservationForProstate"
]
},
"status": "final",
"code": {
"coding": [
{
"system": "http://snomed.org",
"code": "399068003",
"display": "Malignant tumor of prostate (disorder)"
}
]
},
"subject": {
"reference": "Patient/patient01",
"type": "Patient"
},
"valueInteger": 3,
"component": [
{
"code": {
"coding": [
{
"system": "http://loinc.org",
"code": "2857-1",
"display": "Prostate specific Ag [Mass/volume] in Serum or Plasma"
}
]
},
"valueQuantity": {
"value": 3.5,
"unit": "nanogram per millliiter",
"system": "http://unitsofmeasure.org",
"code": "ng/mL"
}
}
]
},
"request": {
"method": "POST",
"url": "Observation"
}
},
{
"resource": {
"resourceType": "Observation",
"id": "observation05",
"meta": {
"profile": [
"https://simplifier.net/INCISIVE/StructureDefinition/ObservationForProstate"
]
},
"status": "final",
"code": {
"coding": [
{
"system": "http://snomed.org",
"code": "399068003",
"display": "Malignant tumor of prostate (disorder)"
}
]
},
"subject": {
"reference": "Patient/patient01",
"type": "Patient"
},
"valueInteger": 4,
"component": [
{
"code": {
"coding": [
{
"system": "http://loinc.org",
"code": "2857-1",
"display": "Prostate specific Ag [Mass/volume] in Serum or Plasma"
}
]
},
"valueQuantity": {
"value": 4.1,
"unit": "nanogram per millliiter",
"system": "http://unitsofmeasure.org",
"code": "ng/mL"
}
}
]
},
"request": {
"method": "POST",
"url": "Observation"
}
},
{
"resource": {
"resourceType": "Observation",
"id": "observation06",
"meta": {
"profile": [
"https://simplifier.net/INCISIVE/StructureDefinition/ObservationForProstate"
]
},
"status": "final",
"code": {
"coding": [
{
"system": "http://snomed.org",
"code": "399068003",
"display": "Malignant tumor of prostate (disorder)"
}
]
},
"subject": {
"reference": "Patient/patient01",
"type": "Patient"
},
"valueInteger": 5,
"component": [
{
"code": {
"coding": [
{
"system": "http://loinc.org",
"code": "2857-1",
"display": "Prostate specific Ag [Mass/volume] in Serum or Plasma"
}
]
},
"valueQuantity": {
"value": 2.7,
"unit": "nanogram per millliiter",
"system": "http://unitsofmeasure.org",
"code": "ng/mL"
}
}
]
},
"request": {
"method": "POST",
"url": "Observation"
}
},
{
"resource": {
"resourceType": "Observation",
"id": "observation07",
"meta": {
"profile": [
"https://simplifier.net/INCISIVE/StructureDefinition/ObservationForProstate"
]
},
"status": "final",
"code": {
"coding": [
{
"system": "http://snomed.org",
"code": "399068003",
"display": "Malignant tumor of prostate (disorder)"
}
]
},
"subject": {
"reference": "Patient/patient01",
"type": "Patient"
},
"valueInteger": 6,
"component": [
{
"code": {
"coding": [
{
"system": "http://loinc.org",
"code": "2857-1",
"display": "Prostate specific Ag [Mass/volume] in Serum or Plasma"
}
]
},
"valueQuantity": {
"value": 5.8,
"unit": "nanogram per millliiter",
"system": "http://unitsofmeasure.org",
"code": "ng/mL"
}
}
]
},
"request": {
"method": "POST",
"url": "Observation"
}
},
{
"resource": {
"resourceType": "Observation",
"id": "observation08",
"meta": {
"profile": [
"https://simplifier.net/INCISIVE/StructureDefinition/ObservationForProstate"
]
},
"status": "final",
"category": [
{
"text": "Between 1st and 2nd dose of CT"
},
{
"text": "Label timepoints"
}
],
"code": {
"coding": [
{
"system": "https://simplifier.net/INCISIVE/CodeSystem/LabelTimepoints",
"code": "1",
"display": "After 1st Treatment"
}
]
},
"subject": {
"reference": "Patient/patient01",
"type": "Patient"
},
"valueInteger": 2,
"component": [
{
"code": {
"coding": [
{
"system": "http://snomed.org",
"code": "399068003:263502005=255318003",
"display": "|Malignant tumor of prostate (disorder)|:|Clinical course (attribute)|=|Relapsing course (qualifier value)|"
}
]
},
"valueBoolean": true
},
{
"code": {
"coding": [
{
"system": "http://snomed.info/sct",
"code": "396152005:726633004=118226009",
"display": "|Raised prostate specific antigen (finding)|:|Temporally related to (attribute)|=|Temporal finding (finding)|"
}
],
"text": "Date of biochemical recurrence - Months from diagnosis"
},
"valueInteger": 2
},
{
"code": {
"coding": [
{
"system": "http://snomed.info/sct",
"code": "396152005:726633004=86631001",
"display": "|Raised prostate specific antigen (finding)|:|Temporally related to (attribute)|=|Absence of signs (finding)|"
}
],
"text": "Free period of BR"
},
"valueInteger": 4
},
{
"code": {
"coding": [
{
"system": "http://snomed.org",
"code": "113091000",
"display": "Magnetic resonance imaging (procedure)"
}
],
"text": "MRI.dcm-path"
},
"valueBoolean": true
},
{
"code": {
"coding": [
{
"system": "http://snomed.org",
"code": "365853002:418775008=113091000",
"display": "|Imaging finding (finding)|:|Finding method (attribute)|=|Magnetic resonance imaging (procedure)|"
}
],
"text": "Annotated MRI.dcm-path"
},
"valueCodeableConcept": {
"coding": [
{
"system": "https://simplifier.net/INCISIVE/CodeSystem/ProstateAnnotatedDicomFiles",
"code": "1",
"display": "Positive annotation"
}
]
}
},
{
"code": {
"coding": [
{
"system": "http://snomed.org",
"code": "77477000",
"display": "Computed tomography (procedure)"
}
],
"text": "CT.dcm-path"
},
"valueBoolean": true
},
{
"code": {
"coding": [
{
"system": "http://snomed.org",
"code": "118247008:418775008=77477000",
"display": "|Radiologic finding (finding)|:|Finding method (attribute)|=|Computed tomography (procedure)|"
}
],
"text": "Annotated CT.dcm-path"
},
"valueCodeableConcept": {
"coding": [
{
"system": "https://simplifier.net/INCISIVE/CodeSystem/ProstateAnnotatedDicomFiles",
"code": "1",
"display": "Positive annotation"
}
]
}
},
{
"code": {
"coding": [
{
"system": "http://snomed.org",
"code": "228084000",
"display": "Whole body bone imaging (procedure)"
}
],
"text": "Bone Scintigraphy Scan.dcm-path"
},
"valueBoolean": true
},
{
"code": {
"coding": [
{
"system": "http://snomed.org",
"code": "118247008:418775008=228084000",
"display": "|Radiologic finding (finding)|:|Finding method (attribute)|=|Whole body bone imaging (procedure)|"
}
],
"text": "Annotated Bone Scintigraphy Scan.dcm-path"
},
"valueCodeableConcept": {
"coding": [
{
"system": "https://simplifier.net/INCISIVE/CodeSystem/ProstateAnnotatedDicomFiles",
"code": "1",
"display": "Positive annotation"
}
]
}
},
{
"code": {
"coding": [
{
"system": "http://snomed.org",
"code": "764685004",
"display": "Positron emission tomography of whole body using choline C-11 (procedure)"
}
],
"text": "PET/CT.dcm-path"
},
"valueBoolean": true
},
{
"code": {
"coding": [
{
"system": "http://snomed.org",
"code": "118247008:418775008=764685004",
"display": "|Radiologic finding (finding)|:|Finding method (attribute)|=|Positron emission tomography of whole body using choline C-11 (procedure)|"
}
],
"text": "Annotated PET/CT.dcm-path"
},
"valueCodeableConcept": {
"coding": [
{
"system": "https://simplifier.net/INCISIVE/CodeSystem/ProstateAnnotatedDicomFiles",
"code": "1",
"display": "Positive annotation"
}
]
}
},
{
"code": {
"coding": [
{
"system": "http://snomed.org",
"code": "252416005",
"display": "Histopathology test (procedure)"
}
],
"text": "Histopathology Image.dcm-path"
},
"valueBoolean": true
},
{
"code": {
"coding": [
{
"system": "http://snomed.org",
"code": "250537006",
"display": "Histopathology finding (finding)"
}
],
"text": "Annotated Histopathology Image.dcm-path"
},
"valueCodeableConcept": {
"coding": [
{
"system": "https://simplifier.net/INCISIVE/CodeSystem/ProstateAnnotatedDicomFiles",
"code": "1",
"display": "Positive annotation"
}
]
}
},
{
"code": {
"coding": [
{
"system": "http://snomed.org",
"code": "363680008",
"display": "Radiographic imaging procedure (procedure)"
}
],
"text": "Xray.dcm-path"
},
"valueBoolean": true
},
{
"code": {
"coding": [
{
"system": "http://snomed.org",
"code": "118247008:418775008=168537006",
"display": "|Radiologic finding (finding)|:|Finding method (attribute)|=|Plain radiography (procedure)|"
}
],
"text": "Annotated Xray.dcm-path"
},
"valueCodeableConcept": {
"coding": [
{
"system": "https://simplifier.net/INCISIVE/CodeSystem/ProstateAnnotatedDicomFiles",
"code": "1",
"display": "Positive annotation"
}
]
}
},
{
"code": {
"coding": [
{
"system": "http://snomed.org",
"code": "108290001",
"display": "Radiation oncology AND/OR radiotherapy (procedure)"
}
]
},
"valueBoolean": true
},
{
"code": {
"coding": [
{
"system": "http://loinc.org",
"code": "2857-1",
"display": "Prostate specific Ag [Mass/volume] in Serum or Plasma"
}
]
},
"valueQuantity": {
"value": 4.26,
"unit": "nanogram per millliiter",
"system": "http://unitsofmeasure.org",
"code": "ng/mL"
}
},
{
"code": {
"coding": [
{
"system": "http://snomed.org",
"code": "707266006",
"display": "Androgen deprivation therapy (procedure)"
}
]
},
"valueBoolean": true
},
{
"code": {
"coding": [
{
"system": "http://snomed.org",
"code": "371497001",
"display": "pM category (observable entity)"
}
]
},
"valueBoolean": true
}
]
},
"request": {
"method": "POST",
"url": "Observation"
}
},
{
"resource": {
"resourceType": "Observation",
"id": "observation09",
"meta": {
"profile": [
"https://simplifier.net/INCISIVE/StructureDefinition/ObservationForProstate"
]
},
"status": "final",
"category": [
{
"text": "Between 1st and 2nd dose of CT"
},
{
"text": "Label treatment"
}
],
"code": {
"coding": [
{
"system": "https://simplifier.net/INCISIVE/CodeSystem/LabelTreatment",
"code": "1",
"display": "After 1st Treatment-1st FollowUp"
}
]
},
"subject": {
"reference": "Patient/patient01",
"type": "Patient"
},
"component": [
{
"code": {
"coding": [
{
"system": "http://snomed.org",
"code": "11971000224104",
"display": "Dissection of lymph node (procedure)"
}
]
},
"valueBoolean": true
},
{
"code": {
"coding": [
{
"system": "http://snomed.org",
"code": "182985004",
"display": "Response to treatment (situation)"
}
]
},
"valueCodeableConcept": {
"coding": [
{
"system": "https://simplifier.net/INCISIVE/CodeSystem/ProstateResponseToTreatment",
"code": "1",
"display": "CR"
}
]
}
}
]
},
"request": {
"method": "POST",
"url": "Observation"
}
},
{
"resource": {
"resourceType": "Procedure",
"id": "procedure01",
"meta": {
"profile": [
"https://simplifier.net/INCISIVE/StructureDefinition/ProcedureForProstate"
]
},
"status": "completed",
"category": {
"coding": [
{
"system": "https://simplifier.net/INCISIVE/CodeSystem/ProstateTypeOfTherapy",
"code": "0",
"display": "EBRT = External Beam Radiotherapy"
}
]
},
"code": {
"coding": [
{
"system": "https://simplifier.net/INCISIVE/CodeSystem/ProstateTreatment",
"code": "1",
"display": "Active surveillance"
}
]
},
"subject": {
"reference": "Patient/patient01",
"type": "Patient"
},
"performedString": "2"
},
"request": {
"method": "POST",
"url": "Procedure"
}
},
{
"resource": {
"resourceType": "Procedure",
"id": "procedure02",
"meta": {
"profile": [
"https://simplifier.net/INCISIVE/StructureDefinition/ProcedureForProstate"
]
},
"status": "completed",
"statusReason": {
"coding": [
{
"system": "https://simplifier.net/INCISIVE/CodeSystem/LabelBiopsy",
"code": "2",
"display": "After 1st Treatment"
}
],
"text": "Biopsy label"
},
"category": {
"coding": [
{
"system": "https://simplifier.net/INCISIVE/CodeSystem/ProstateTypeOfBiopsy",
"code": "1",
"display": "Randomized biopsy"
}
],
"text": "Between 1st and 2nd dose of CT"
},
"code": {
"coding": [
{
"system": "http://snomed.org",
"code": "86273004",
"display": "Biopsy (procedure)"
}
]
},
"subject": {
"reference": "Patient/patient01",
"type": "Patient"
},
"performedString": "3"
},
"request": {
"method": "POST",
"url": "Procedure"
}
},
{
"resource": {
"resourceType": "Observation",
"id": "observation10",
"meta": {
"profile": [
"https://simplifier.net/INCISIVE/StructureDefinition/ObservationForProstate"
]
},
"partOf": [
{
"reference": "Procedure/procedure02"
}
],
"status": "final",
"code": {
"coding": [
{
"system": "http://snomed.org",
"code": "399068003",
"display": "Malignant tumor of prostate (disorder)"
}
]
},
"subject": {
"reference": "Patient/patient01",
"type": "Patient"
},
"component": [
{
"code": {
"coding": [
{
"system": "http://snomed.org",
"code": "372278000",
"display": "Gleason score (observable entity)"
}
]
},
"valueInteger": 7
},
{
"code": {
"coding": [
{
"system": "http://snomed.org",
"code": "396659000",
"display": "Histologic grade of urothelial carcinoma by World Health Organization and International Society of Urological Pathology technique (observable entity)"
}
]
},
"valueInteger": 4
},
{
"code": {
"coding": [
{
"system": "http://snomed.org",
"code": "372280006:704325000=251597001",
"display": "|Ratio of number of prostatic tissue cores positive for carcinoma to total number of cores obtained by needle biopsy (observable entity)|:|Relative to (attribute)|=|Structure of right lateral lobe of prostate (body structure)|"
}
]
},
"valueQuantity": {
"value": 95,
"unit": "% percent",
"system": "http://unitsofmeasure.org",
"code": "%"
}
},
{
"code": {
"coding": [
{
"system": "http://snomed.org",
"code": "372280006:704325000=251695000",
"display": "|Ratio of number of prostatic tissue cores positive for carcinoma to total number of cores obtained by needle biopsy (observable entity)|:|Relative to (attribute)|=|Structure of left lateral lobe of prostate (body structure)|"
}
]
},
"valueQuantity": {
"value": 60,
"unit": "% percent",
"system": "http://unitsofmeasure.org",
"code": "%"
}
},
{
"code": {
"coding": [
{
"system": "http://snomed.org",
"code": "86616005",
"display": "Non-infiltrating intraductal carcinoma (morphologic abnormality)"
}
]
},
"valueBoolean": true
},
{
"code": {
"coding": [
{
"system": "http://snomed.org",
"code": "443987001",
"display": "Cribriform neoplasm pattern (finding)"
}
]
},
"valueBoolean": true
},
{
"code": {
"coding": [
{
"system": "http://snomed.org",
"code": "1229861009",
"display": "American Joint Committee on Cancer pT3b (qualifier value)"
}
]
},
"valueBoolean": true
},
{
"code": {
"coding": [
{
"system": "http://snomed.org",
"code": "1229859000",
"display": "American Joint Committee on Cancer pT3 (qualifier value)"
}
]
},
"valueBoolean": true
},
{
"code": {
"coding": [
{
"system": "http://snomed.org",
"code": "372278000",
"display": "Gleason score (observable entity)"
}
]
},
"valueInteger": 6
},
{
"code": {
"coding": [
{
"system": "http://snomed.org",
"code": "1222589003",
"display": "American Joint Committee on Cancer pathological T category allowable value (qualifier value)"
}
]
},
"valueCodeableConcept": {
"coding": [
{
"system": "https://simplifier.net/INCISIVE/CodeSystem/ProstatePTHistologyMutations",
"code": "1",
"display": "pT1"
}
]
}
},
{
"code": {
"coding": [
{
"system": "http://snomed.org",
"code": "1222590007",
"display": "American Joint Committee on Cancer pathological N category allowable value (qualifier value)"
}
]
},
"valueCodeableConcept": {
"coding": [
{
"system": "https://simplifier.net/INCISIVE/CodeSystem/ProstatePNHistologyMutations",
"code": "1",
"display": "N1"
}
]
}
}
]
},
"request": {
"method": "POST",
"url": "Observation"
}
},
{
"resource": {
"resourceType": "Observation",
"id": "observation11",
"meta": {
"profile": [
"https://simplifier.net/INCISIVE/StructureDefinition/ObservationForProstate"
]
},
"status": "final",
"code": {
"coding": [
{
"system": "http://snomed.org",
"code": "399068003",
"display": "Malignant tumor of prostate (disorder)"
}
]
},
"subject": {
"reference": "Patient/patient01",
"type": "Patient"
},
"component": [
{
"code": {
"coding": [
{
"system": "http://snomed.org",
"code": "257915005",
"display": "Sampling - action (qualifier value)"
}
]
},
"valueString": "Light microscopy"
},
{
"code": {
"coding": [
{
"system": "http://snomed.org",
"code": "127790008",
"display": "Staining method (procedure)"
}
]
},
"valueString": "Hematoxylin"
},
{
"code": {
"coding": [
{
"system": "http://snomed.org",
"code": "395538009",
"display": "Microscopic specimen observation (finding)"
}
]
},
"valueString": "x10"
},
{
"code": {
"coding": [
{
"system": "http://snomed.org",
"code": "365855009",
"display": "Biopsy finding (finding)"
}
]
},
"valueString": "example"
}
]
},
"request": {
"method": "POST",
"url": "Observation"
}
},
{
"resource": {
"resourceType": "Observation",
"id": "observation12",
"meta": {
"profile": [
"https://simplifier.net/INCISIVE/StructureDefinition/ObservationForProstate"
]
},
"status": "final",
"category": [
{
"text": "Between 1st and 2nd dose of CT"
},
{
"text": "Exam label"
}
],
"code": {
"coding": [
{
"system": "https://simplifier.net/INCISIVE/CodeSystem/LabelExam",
"code": "1",
"display": "After 1st Treatment"
}
]
},
"subject": {
"reference": "Patient/patient01",
"type": "Patient"
},
"valueInteger": 2,
"component": [
{
"code": {
"coding": [
{
"system": "http://loinc.org",
"code": "95218-4",
"display": "Leukocytes [#/volume] in Stem cell product"
}
]
},
"valueQuantity": {
"value": 15.8,
"unit": "per microlitre",
"system": "http://unitsofmeasure.org",
"code": "x10^9/L"
}
},
{
"code": {
"coding": [
{
"system": "http://loinc.org",
"code": "718-7",
"display": "Hemoglobin [Mass/volume] in Blood"
}
]
},
"valueQuantity": {
"value": 16.7,
"unit": "gram per decilitre",
"system": "http://unitsofmeasure.org",
"code": "gr/dL"
}
},
{
"code": {
"coding": [
{
"system": "http://loinc.org",
"code": "20570-8",
"display": "Hematocrit [Volume Fraction] of Blood"
}
]
},
"valueQuantity": {
"value": 47.4,
"unit": "% percent",
"system": "http://unitsofmeasure.org",
"code": "%"
}
},
{
"code": {
"coding": [
{
"system": "http://loinc.org",
"code": "26515-7",
"display": "Platelets [#/volume] in Blood"
}
]
},
"valueQuantity": {
"value": 287,
"unit": "per nanolitre",
"system": "http://unitsofmeasure.org",
"code": "x10^3/μL"
}
},
{
"code": {
"coding": [
{
"system": "http://loinc.org",
"code": "41652-9",
"display": "Glucose [Mass/volume] in Venous blood"
}
]
},
"valueQuantity": {
"value": 87,
"unit": "milligram per decilitre",
"system": "http://unitsofmeasure.org",
"code": "mg/dL"
}
},
{
"code": {
"coding": [
{
"system": "http://loinc.org",
"code": "20448-7",
"display": "Insulin [Units/volume] in Serum or Plasma"
}
]
},
"valueQuantity": {
"value": 4,
"unit": "milli-international unit per litre",
"system": "http://unitsofmeasure.org",
"code": "mlU/L"
}
},
{
"code": {
"coding": [
{
"system": "http://loinc.org",
"code": "20977-5",
"display": "Urea [Mass/volume] in Blood"
}
]
},
"valueQuantity": {
"value": 36,
"unit": "milligram per decilitre",
"system": "http://unitsofmeasure.org",
"code": "mg/dL"
}
},
{
"code": {
"coding": [
{
"system": "http://loinc.org",
"code": "38483-4",
"display": "Creatinine [Mass/volume] in Blood"
}
]
},
"valueQuantity": {
"value": 0.72,
"unit": "milligram per decilitre",
"system": "http://unitsofmeasure.org",
"code": "mg/dL"
}
},
{
"code": {
"coding": [
{
"system": "http://loinc.org",
"code": "98981-4",
"display": "Urate [Mass/volume] in Blood"
}
]
},
"valueQuantity": {
"value": 3.5,
"unit": "milligram per decilitre",
"system": "http://unitsofmeasure.org",
"code": "mg/dL"
}
},
{
"code": {
"coding": [
{
"system": "http://loinc.org",
"code": "75940-7",
"display": "Potassium [Mass/volume] in Blood"
}
]
},
"valueQuantity": {
"value": 4.8,
"unit": "millimole per litre",
"system": "http://unitsofmeasure.org",
"code": "mmol/L"
}
},
{
"code": {
"coding": [
{
"system": "http://loinc.org",
"code": "2947-0",
"display": "Sodium [Moles/volume] in Blood"
}
]
},
"valueQuantity": {
"value": 142,
"unit": "millimole per litre",
"system": "http://unitsofmeasure.org",
"code": "mmol/L"
}
},
{
"code": {
"coding": [
{
"system": "http://loinc.org",
"code": "49765-1",
"display": "Calcium [Mass/volume] in Blood"
}
]
},
"valueQuantity": {
"value": 9.31,
"unit": "milligram per decilitre",
"system": "http://unitsofmeasure.org",
"code": "mg/dL"
}
},
{
"code": {
"coding": [
{
"system": "http://loinc.org",
"code": "2093-3",
"display": "Cholesterol [Mass/volume] in Serum or Plasma"
}
]
},
"valueQuantity": {
"value": 197,
"unit": "milligram per decilitre",
"system": "http://unitsofmeasure.org",
"code": "mg/dL"
}
},
{
"code": {
"coding": [
{
"system": "http://loinc.org",
"code": "3043-7",
"display": "Triglyceride [Mass/volume] in Blood"
}
]
},
"valueQuantity": {
"value": 59,
"unit": "milligram per decilitre",
"system": "http://unitsofmeasure.org",
"code": "mg/dL"
}
},
{
"code": {
"coding": [
{
"system": "http://loinc.org",
"code": "2085-9",
"display": "Cholesterol in HDL [Mass/volume] in Serum or Plasma"
}
]
},
"valueQuantity": {
"value": 60,
"unit": "milligram per decilitre",
"system": "http://unitsofmeasure.org",
"code": "mg/dL"
}
},
{
"code": {
"coding": [
{
"system": "http://loinc.org",
"code": "2089-1",
"display": "Cholesterol in LDL [Mass/volume] in Serum or Plasma"
}
]
},
"valueQuantity": {
"value": 120,
"unit": "milligram per decilitre",
"system": "http://unitsofmeasure.org",
"code": "mg/dL"
}
},
{
"code": {
"coding": [
{
"system": "http://loinc.org",
"code": "1920-8",
"display": "Aspartate aminotransferase [Enzymatic activity/volume] in Serum or Plasma"
}
]
},
"valueQuantity": {
"value": 19,
"unit": "enzyme unit per litre",
"system": "http://unitsofmeasure.org",
"code": "U/L"
}
},
{
"code": {
"coding": [
{
"system": "http://loinc.org",
"code": "76625-3",
"display": "Alanine aminotransferase [Enzymatic activity/volume] in Blood"
}
]
},
"valueQuantity": {
"value": 33,
"unit": "enzyme unit per litre",
"system": "http://unitsofmeasure.org",
"code": "U/L"
}
},
{
"code": {
"coding": [
{
"system": "http://loinc.org",
"code": "2324-2",
"display": "Gamma glutamyl transferase [Enzymatic activity/volume] in Serum or Plasma"
}
]
},
"valueQuantity": {
"value": 14,
"unit": "enzyme unit per litre",
"system": "http://unitsofmeasure.org",
"code": "U/L"
}
},
{
"code": {
"coding": [
{
"system": "http://loinc.org",
"code": "1783-0",
"display": "Alkaline phosphatase [Enzymatic activity/volume] in Blood"
}
]
},
"valueQuantity": {
"value": 227,
"unit": "enzyme unit per litre",
"system": "http://unitsofmeasure.org",
"code": "U/L"
}
},
{
"code": {
"coding": [
{
"system": "http://loinc.org",
"code": "11053-6",
"display": "Lactate dehydrogenase [Enzymatic activity/volume] in Red Blood Cells"
}
]
},
"valueQuantity": {
"value": 270,
"unit": "enzyme unit per litre",
"system": "http://unitsofmeasure.org",
"code": "U/L"
}
},
{
"code": {
"coding": [
{
"system": "http://loinc.org",
"code": "3015-5",
"display": "Thyrotropin [Units/volume] in Blood"
}
]
},
"valueQuantity": {
"value": 0.73,
"unit": "milli-international unit per litre",
"system": "http://unitsofmeasure.org",
"code": "mlU/L"
}
},
{
"code": {
"coding": [
{
"system": "http://loinc.org",
"code": "2143-6",
"display": "Cortisol [Mass/volume] in Serum or Plasma"
}
]
},
"valueQuantity": {
"value": 22,
"unit": "gram per decilitre",
"system": "http://unitsofmeasure.org",
"code": "g/dL"
}
},
{
"code": {
"coding": [
{
"system": "http://loinc.org",
"code": "71426-1",
"display": "C reactive protein [Mass/volume] in Blood by High sensitivity method"
}
]
},
"valueQuantity": {
"value": 0.5,
"unit": "milligram per decilitre",
"system": "http://unitsofmeasure.org",
"code": "mg/dL"
}
},
{
"code": {
"coding": [
{
"system": "http://loinc.org",
"code": "42637-9",
"display": "Natriuretic peptide B [Mass/volume] in Blood"
}
]
},
"valueQuantity": {
"value": 120,
"unit": "picogram per millilitre",
"system": "http://unitsofmeasure.org",
"code": "pg/mL"
}
},
{
"code": {
"coding": [
{
"system": "http://loinc.org",
"code": "17856-6",
"display": "Hemoglobin A1c/Hemoglobin.total in Blood by HPLC"
}
]
},
"valueQuantity": {
"value": 5.1,
"unit": "% percent",
"system": "http://unitsofmeasure.org",
"code": "%"
}
},
{
"code": {
"coding": [
{
"system": "http://loinc.org",
"code": "13986-5",
"display": "Albumin/Protein.total in 24 hour Urine by Electrophoresis"
}
]
},
"valueQuantity": {
"value": 80,
"unit": "milligram per 24 hour",
"system": "http://unitsofmeasure.org",
"code": "mg/24h"
}
},
{
"code": {
"coding": [
{
"system": "http://loinc.org",
"code": "2161-8",
"display": "Creatinine [Mass/volume] in Urine"
}
]
},
"valueQuantity": {
"value": 100,
"unit": "milligram per decilitre",
"system": "http://unitsofmeasure.org",
"code": "mg/dL"
}
}
]
},
"request": {
"method": "POST",
"url": "Observation"
}
}
]
}