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Packagehl7.fhir.uv.xver-r5.r4
Resource TypeStructureDefinition
IdStructureDefinition-ext-R5-Evidence.statistic.json
FHIR VersionR4

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Narrative

Note: links and images are rebased to the (stated) source

Generated Narrative: StructureDefinition ext-R5-Evidence.statistic

NameFlagsCard.TypeDescription & Constraintsdoco
.. Extension 0..*Extension(4.0.1)R5: Values and parameters for a single statistic (new)
... Slices for extension 0..*ExtensionExtension
Slice: Unordered, Open by value:url
.... extension:description 0..1ExtensionR5: Description of content (new)
..... url 1..1uri"description"
..... value[x] 0..1markdownDescription of content
.... extension:note 0..*ExtensionR5: Footnotes and/or explanatory notes (new)
..... url 1..1uri"note"
..... value[x] 0..1AnnotationFootnotes and/or explanatory notes
.... extension:statisticType 0..1ExtensionR5: Type of statistic, e.g., relative risk (new)
..... url 1..1uri"statisticType"
..... value[x] 0..1CodeableConceptType of statistic, e.g., relative risk
Binding: R5StatisticTypeForR4 (0.1.0) (extensible)
.... extension:category 0..1ExtensionR5: Associated category for categorical variable (new)
..... url 1..1uri"category"
..... value[x] 0..1CodeableConceptAssociated category for categorical variable
.... extension:quantity 0..1ExtensionR5: Statistic value (new)
..... url 1..1uri"quantity"
..... value[x] 0..1QuantityStatistic value
.... extension:numberOfEvents 0..1ExtensionR5: The number of events associated with the statistic (new)
..... url 1..1uri"numberOfEvents"
..... value[x] 0..1unsignedIntThe number of events associated with the statistic
.... extension:numberAffected 0..1ExtensionR5: The number of participants affected (new)
..... url 1..1uri"numberAffected"
..... value[x] 0..1unsignedIntThe number of participants affected
.... extension:sampleSize 0..1ExtensionR5: Number of samples in the statistic (new)
..... Slices for extension 0..*ExtensionExtension
Slice: Unordered, Open by value:url
...... extension:description 0..1ExtensionR5: Textual description of sample size for statistic (new)
....... url 1..1uri"description"
....... value[x] 0..1markdownTextual description of sample size for statistic
...... extension:note 0..*ExtensionR5: Footnote or explanatory note about the sample size (new)
....... url 1..1uri"note"
....... value[x] 0..1AnnotationFootnote or explanatory note about the sample size
...... extension:numberOfStudies 0..1ExtensionR5: Number of contributing studies (new)
....... url 1..1uri"numberOfStudies"
....... value[x] 0..1unsignedIntNumber of contributing studies
...... extension:numberOfParticipants 0..1ExtensionR5: Cumulative number of participants (new)
....... url 1..1uri"numberOfParticipants"
....... value[x] 0..1unsignedIntCumulative number of participants
...... extension:knownDataCount 0..1ExtensionR5: Number of participants with known results for measured variables (new)
....... url 1..1uri"knownDataCount"
....... value[x] 0..1unsignedIntNumber of participants with known results for measured variables
..... url 1..1uri"sampleSize"
..... value[x] 0..0Value of extension
.... extension:attributeEstimate 0..*ExtensionR5: An attribute of the Statistic (new)
..... Slices for extension 0..*ExtensionExtension
Slice: Unordered, Open by value:url
...... extension:description 0..1ExtensionR5: Textual description of the attribute estimate (new)
....... url 1..1uri"description"
....... value[x] 0..1markdownTextual description of the attribute estimate
...... extension:note 0..*ExtensionR5: Footnote or explanatory note about the estimate (new)
....... url 1..1uri"note"
....... value[x] 0..1AnnotationFootnote or explanatory note about the estimate
...... extension:type 0..1ExtensionR5: The type of attribute estimate, e.g., confidence interval or p value (new)
....... url 1..1uri"type"
....... value[x] 0..1CodeableConceptThe type of attribute estimate, e.g., confidence interval or p value
Binding: R5AttributeEstimateTypeForR4 (0.1.0) (extensible)
...... extension:quantity 0..1ExtensionR5: The singular quantity of the attribute estimate, for attribute estimates represented as single values; also used to report unit of measure (new)
....... url 1..1uri"quantity"
....... value[x] 0..1QuantityThe singular quantity of the attribute estimate, for attribute estimates represented as single values; also used to report unit of measure
...... extension:level 0..1ExtensionR5: Level of confidence interval, e.g., 0.95 for 95% confidence interval (new)
....... url 1..1uri"level"
....... value[x] 0..1decimalLevel of confidence interval, e.g., 0.95 for 95% confidence interval
...... extension:range 0..1ExtensionR5: Lower and upper bound values of the attribute estimate (new)
....... url 1..1uri"range"
....... value[x] 0..1RangeLower and upper bound values of the attribute estimate
...... extension:attributeEstimate 0..*ExtensionR5: A nested attribute estimate; which is the attribute estimate of an attribute estimate (new)
....... url 1..1uri"http://hl7.org/fhir/5.0/StructureDefinition/extension-Evidence.statistic.attributeEstimate"
....... value[x] 0..0Value of extension
..... url 1..1uri"attributeEstimate"
..... value[x] 0..0Value of extension
.... extension:modelCharacteristic 0..*ExtensionR5: An aspect of the statistical model (new)
..... Slices for extension 1..*ExtensionExtension
Slice: Unordered, Open by value:url
...... extension:code 1..1ExtensionR5: Model specification (new)
....... url 1..1uri"code"
....... value[x] 1..1CodeableConceptModel specification
Binding: R5StatisticModelCodeForR4 (0.1.0) (extensible)
...... extension:value 0..1ExtensionR5: Numerical value to complete model specification (new)
....... url 1..1uri"value"
....... value[x] 0..1SimpleQuantity(4.0.1)Numerical value to complete model specification
...... extension:variable 0..*ExtensionR5: A variable adjusted for in the adjusted analysis (new)
....... Slices for extension 1..*ExtensionExtension
Slice: Unordered, Open by value:url
........ extension:variableDefinition 1..1ExtensionR5: Description of the variable (new)
......... url 1..1uri"variableDefinition"
......... value[x] 1..1Reference(Cross-version Profile for R5.Group for use in FHIR R4(0.1.0) | Group | Cross-version Profile for R5.EvidenceVariable for use in FHIR R4(0.1.0) | EvidenceVariable)Description of the variable
........ extension:handling 0..1ExtensionR5: continuous | dichotomous | ordinal | polychotomous (new)
......... url 1..1uri"handling"
......... value[x] 0..1codecontinuous | dichotomous | ordinal | polychotomous
Binding: R5VariableHandlingForR4 (0.1.0) (required)
........ extension:valueCategory 0..*ExtensionR5: Description for grouping of ordinal or polychotomous variables (new)
......... url 1..1uri"valueCategory"
......... value[x] 0..1CodeableConceptDescription for grouping of ordinal or polychotomous variables
........ extension:valueQuantity 0..*ExtensionR5: Discrete value for grouping of ordinal or polychotomous variables (new)
......... url 1..1uri"valueQuantity"
......... value[x] 0..1QuantityDiscrete value for grouping of ordinal or polychotomous variables
........ extension:valueRange 0..*ExtensionR5: Range of values for grouping of ordinal or polychotomous variables (new)
......... url 1..1uri"valueRange"
......... value[x] 0..1RangeRange of values for grouping of ordinal or polychotomous variables
....... url 1..1uri"variable"
....... value[x] 0..0Value of extension
...... extension:attributeEstimate 0..*ExtensionR5: An attribute of the statistic used as a model characteristic (new)
....... url 1..1uri"http://hl7.org/fhir/5.0/StructureDefinition/extension-Evidence.statistic.attributeEstimate"
....... value[x] 0..0Value of extension
..... url 1..1uri"modelCharacteristic"
..... value[x] 0..0Value of extension
... url 1..1uri"http://hl7.org/fhir/5.0/StructureDefinition/extension-Evidence.statistic"
... value[x] 0..0Value of extension

doco Documentation for this format

Source1

{
  "resourceType": "StructureDefinition",
  "id": "ext-R5-Evidence.statistic",
  "text": {
    "status": "extensions",
    "div": "<!-- snip (see above) -->"
  },
  "extension": [
    {
      "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-wg",
      "valueCode": "fhir"
    },
    {
      "extension": [
        {
          "url": "packageId",
          "valueId": "hl7.fhir.uv.xver-r5.r4"
        },
        {
          "url": "version",
          "valueString": "0.1.0"
        },
        {
          "url": "uri",
          "valueUri": "http://hl7.org/fhir/uv/xver/ImplementationGuide/hl7.fhir.uv.xver-r5.r4"
        }
      ],
      "url": "http://hl7.org/fhir/StructureDefinition/package-source"
    },
    {
      "extension": [
        {
          "url": "startFhirVersion",
          "valueCode": "4.0"
        },
        {
          "url": "endFhirVersion",
          "valueCode": "4.0"
        }
      ],
      "url": "http://hl7.org/fhir/StructureDefinition/version-specific-use"
    },
    {
      "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fmm",
      "valueInteger": 0,
      "_valueInteger": {
        "extension": [
          {
            "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-conformance-derivedFrom",
            "valueCanonical": "http://hl7.org/fhir/uv/xver/ImplementationGuide/hl7.fhir.uv.xver-r5.r4"
          }
        ]
      }
    },
    {
      "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status",
      "valueCode": "trial-use",
      "_valueCode": {
        "extension": [
          {
            "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-conformance-derivedFrom",
            "valueCanonical": "http://hl7.org/fhir/uv/xver/ImplementationGuide/hl7.fhir.uv.xver-r5.r4"
          }
        ]
      }
    }
  ],
  "url": "http://hl7.org/fhir/5.0/StructureDefinition/extension-Evidence.statistic",
  "version": "0.1.0",
  "name": "ExtensionEvidence_Statistic",
  "title": "R5: Values and parameters for a single statistic (new)",
  "status": "active",
  "experimental": false,
  "date": "2026-03-17T21:02:03.8104715+00:00",
  "publisher": "FHIR Infrastructure",
  "contact": [
    {
      "name": "FHIR Infrastructure",
      "telecom": [
        {
          "system": "url",
          "value": "http://www.hl7.org/Special/committees/fiwg"
        }
      ]
    }
  ],
  "description": "R5: `Evidence.statistic` (new:BackboneElement)",
  "jurisdiction": [
    {
      "coding": [
        {
          "system": "http://unstats.un.org/unsd/methods/m49/m49.htm",
          "code": "001",
          "display": "World"
        }
      ]
    }
  ],
  "purpose": "This extension is part of the cross-version definitions generated to enable use of the\r\nelement `Evidence.statistic` as defined in FHIR R5\r\nin FHIR R4.\r\n\r\nThe source element is defined as:\r\n`Evidence.statistic` 0..* `BackboneElement`\r\n\r\nAcross FHIR versions, the element set has been mapped as:\r\n*  R5: `Evidence.statistic` 0..* `BackboneElement`\n*  R4B: `Evidence.statistic` 0..* `BackboneElement`\r\n\r\nFollowing are the generation technical comments:\r\nElement `Evidence.statistic` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
  "fhirVersion": "4.0.1",
  "mapping": [
    {
      "identity": "rim",
      "uri": "http://hl7.org/v3",
      "name": "RIM Mapping"
    }
  ],
  "kind": "complex-type",
  "abstract": false,
  "context": [
    {
      "type": "element",
      "expression": "Evidence"
    }
  ],
  "type": "Extension",
  "baseDefinition": "http://hl7.org/fhir/StructureDefinition/Extension|4.0.1",
  "derivation": "constraint",
  "snapshot": {
    "extension": [
      {
        "url": "http://hl7.org/fhir/tools/StructureDefinition/snapshot-base-version",
        "valueString": "4.0.1"
      }
    ],
    "element": [
      {
        "id": "Extension",
        "path": "Extension",
        "short": "R5: Values and parameters for a single statistic (new)",
        "definition": "R5: `Evidence.statistic` (new:BackboneElement)",
        "comment": "Element `Evidence.statistic` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
        "min": 0,
        "max": "*",
        "base": {
          "path": "Extension",
          "min": 0,
          "max": "*"
        },
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element|4.0.1"
          },
          {
            "key": "ext-1",
            "severity": "error",
            "human": "Must have either extensions or value[x], not both",
            "expression": "extension.exists() != value.exists()",
            "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), 'value')])",
            "source": "http://hl7.org/fhir/StructureDefinition/Extension|4.0.1"
          }
        ],
        "isModifier": false
      },
      {
        "id": "Extension.id",
        "path": "Extension.id",
        "representation": [
          "xmlAttr"
        ],
        "short": "Unique id for inter-element referencing",
        "definition": "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Element.id",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
                "valueUrl": "string"
              }
            ],
            "code": "http://hl7.org/fhirpath/System.String"
          }
        ],
        "isModifier": false,
        "isSummary": false,
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          }
        ]
      },
      {
        "id": "Extension.extension",
        "path": "Extension.extension",
        "slicing": {
          "discriminator": [
            {
              "type": "value",
              "path": "url"
            }
          ],
          "description": "Extensions are always sliced by (at least) url",
          "ordered": false,
          "rules": "open"
        },
        "short": "Extension",
        "definition": "An Extension",
        "min": 0,
        "max": "*",
        "base": {
          "path": "Element.extension",
          "min": 0,
          "max": "*"
        },
        "type": [
          {
            "code": "Extension"
          }
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element|4.0.1"
          },
          {
            "key": "ext-1",
            "severity": "error",
            "human": "Must have either extensions or value[x], not both",
            "expression": "extension.exists() != value.exists()",
            "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
            "source": "http://hl7.org/fhir/StructureDefinition/Extension|4.0.1"
          }
        ],
        "isModifier": false,
        "isSummary": false
      },
      {
        "id": "Extension.extension:description",
        "path": "Extension.extension",
        "sliceName": "description",
        "short": "R5: Description of content (new)",
        "definition": "R5: `Evidence.statistic.description` (new:markdown)",
        "comment": "Element `Evidence.statistic.description` is part of an existing definition because parent element `Evidence.statistic` requires a cross-version extension.\nElement `Evidence.statistic.description` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.description` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
        "requirements": "Element `Evidence.statistic.description` is part of an existing definition because parent element `Evidence.statistic` requires a cross-version extension.\nElement `Evidence.statistic.description` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.description` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Element.extension",
          "min": 0,
          "max": "*"
        },
        "type": [
          {
            "code": "Extension"
          }
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element|4.0.1"
          },
          {
            "key": "ext-1",
            "severity": "error",
            "human": "Must have either extensions or value[x], not both",
            "expression": "extension.exists() != value.exists()",
            "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
            "source": "http://hl7.org/fhir/StructureDefinition/Extension|4.0.1"
          }
        ],
        "isModifier": false,
        "isSummary": false
      },
      {
        "id": "Extension.extension:description.id",
        "path": "Extension.extension.id",
        "representation": [
          "xmlAttr"
        ],
        "short": "Unique id for inter-element referencing",
        "definition": "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Element.id",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
                "valueUrl": "string"
              }
            ],
            "code": "http://hl7.org/fhirpath/System.String"
          }
        ],
        "isModifier": false,
        "isSummary": false,
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          }
        ]
      },
      {
        "id": "Extension.extension:description.extension",
        "path": "Extension.extension.extension",
        "slicing": {
          "discriminator": [
            {
              "type": "value",
              "path": "url"
            }
          ],
          "description": "Extensions are always sliced by (at least) url",
          "rules": "open"
        },
        "short": "Additional content defined by implementations",
        "definition": "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance  applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.",
        "comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
        "alias": [
          "extensions",
          "user content"
        ],
        "min": 0,
        "max": "*",
        "base": {
          "path": "Element.extension",
          "min": 0,
          "max": "*"
        },
        "type": [
          {
            "code": "Extension"
          }
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element|4.0.1"
          },
          {
            "key": "ext-1",
            "severity": "error",
            "human": "Must have either extensions or value[x], not both",
            "expression": "extension.exists() != value.exists()",
            "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
            "source": "http://hl7.org/fhir/StructureDefinition/Extension|4.0.1"
          }
        ],
        "isModifier": false,
        "isSummary": false,
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          }
        ]
      },
      {
        "id": "Extension.extension:description.url",
        "path": "Extension.extension.url",
        "representation": [
          "xmlAttr"
        ],
        "short": "identifies the meaning of the extension",
        "definition": "Source of the definition for the extension code - a logical name or a URL.",
        "comment": "The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.",
        "min": 1,
        "max": "1",
        "base": {
          "path": "Extension.url",
          "min": 1,
          "max": "1"
        },
        "type": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
                "valueUrl": "uri"
              }
            ],
            "code": "http://hl7.org/fhirpath/System.String"
          }
        ],
        "fixedUri": "description",
        "isModifier": false,
        "isSummary": false,
        "mapping": [
          {
            "identity": "rim",
            "map": "N/A"
          }
        ]
      },
      {
        "id": "Extension.extension:description.value[x]",
        "path": "Extension.extension.value[x]",
        "short": "Description of content",
        "definition": "A description of the content value of the statistic.",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Extension.value[x]",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "markdown"
          }
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element|4.0.1"
          }
        ],
        "isModifier": false,
        "isSummary": false,
        "mapping": [
          {
            "identity": "rim",
            "map": "N/A"
          }
        ]
      },
      {
        "id": "Extension.extension:note",
        "path": "Extension.extension",
        "sliceName": "note",
        "short": "R5: Footnotes and/or explanatory notes (new)",
        "definition": "R5: `Evidence.statistic.note` (new:Annotation)",
        "comment": "Element `Evidence.statistic.note` is part of an existing definition because parent element `Evidence.statistic` requires a cross-version extension.\nElement `Evidence.statistic.note` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.note` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
        "requirements": "Element `Evidence.statistic.note` is part of an existing definition because parent element `Evidence.statistic` requires a cross-version extension.\nElement `Evidence.statistic.note` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.note` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
        "min": 0,
        "max": "*",
        "base": {
          "path": "Element.extension",
          "min": 0,
          "max": "*"
        },
        "type": [
          {
            "code": "Extension"
          }
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element|4.0.1"
          },
          {
            "key": "ext-1",
            "severity": "error",
            "human": "Must have either extensions or value[x], not both",
            "expression": "extension.exists() != value.exists()",
            "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
            "source": "http://hl7.org/fhir/StructureDefinition/Extension|4.0.1"
          }
        ],
        "isModifier": false,
        "isSummary": false
      },
      {
        "id": "Extension.extension:note.id",
        "path": "Extension.extension.id",
        "representation": [
          "xmlAttr"
        ],
        "short": "Unique id for inter-element referencing",
        "definition": "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Element.id",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
                "valueUrl": "string"
              }
            ],
            "code": "http://hl7.org/fhirpath/System.String"
          }
        ],
        "isModifier": false,
        "isSummary": false,
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          }
        ]
      },
      {
        "id": "Extension.extension:note.extension",
        "path": "Extension.extension.extension",
        "slicing": {
          "discriminator": [
            {
              "type": "value",
              "path": "url"
            }
          ],
          "description": "Extensions are always sliced by (at least) url",
          "rules": "open"
        },
        "short": "Additional content defined by implementations",
        "definition": "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance  applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.",
        "comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
        "alias": [
          "extensions",
          "user content"
        ],
        "min": 0,
        "max": "*",
        "base": {
          "path": "Element.extension",
          "min": 0,
          "max": "*"
        },
        "type": [
          {
            "code": "Extension"
          }
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element|4.0.1"
          },
          {
            "key": "ext-1",
            "severity": "error",
            "human": "Must have either extensions or value[x], not both",
            "expression": "extension.exists() != value.exists()",
            "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
            "source": "http://hl7.org/fhir/StructureDefinition/Extension|4.0.1"
          }
        ],
        "isModifier": false,
        "isSummary": false,
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          }
        ]
      },
      {
        "id": "Extension.extension:note.url",
        "path": "Extension.extension.url",
        "representation": [
          "xmlAttr"
        ],
        "short": "identifies the meaning of the extension",
        "definition": "Source of the definition for the extension code - a logical name or a URL.",
        "comment": "The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.",
        "min": 1,
        "max": "1",
        "base": {
          "path": "Extension.url",
          "min": 1,
          "max": "1"
        },
        "type": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
                "valueUrl": "uri"
              }
            ],
            "code": "http://hl7.org/fhirpath/System.String"
          }
        ],
        "fixedUri": "note",
        "isModifier": false,
        "isSummary": false,
        "mapping": [
          {
            "identity": "rim",
            "map": "N/A"
          }
        ]
      },
      {
        "id": "Extension.extension:note.value[x]",
        "path": "Extension.extension.value[x]",
        "short": "Footnotes and/or explanatory notes",
        "definition": "Footnotes and/or explanatory notes.",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Extension.value[x]",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "Annotation"
          }
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element|4.0.1"
          }
        ],
        "isModifier": false,
        "isSummary": false,
        "mapping": [
          {
            "identity": "rim",
            "map": "N/A"
          }
        ]
      },
      {
        "id": "Extension.extension:statisticType",
        "path": "Extension.extension",
        "sliceName": "statisticType",
        "short": "R5: Type of statistic, e.g., relative risk (new)",
        "definition": "R5: `Evidence.statistic.statisticType` (new:CodeableConcept)",
        "comment": "Element `Evidence.statistic.statisticType` is part of an existing definition because parent element `Evidence.statistic` requires a cross-version extension.\nElement `Evidence.statistic.statisticType` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.statisticType` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
        "requirements": "Element `Evidence.statistic.statisticType` is part of an existing definition because parent element `Evidence.statistic` requires a cross-version extension.\nElement `Evidence.statistic.statisticType` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.statisticType` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Element.extension",
          "min": 0,
          "max": "*"
        },
        "type": [
          {
            "code": "Extension"
          }
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element|4.0.1"
          },
          {
            "key": "ext-1",
            "severity": "error",
            "human": "Must have either extensions or value[x], not both",
            "expression": "extension.exists() != value.exists()",
            "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
            "source": "http://hl7.org/fhir/StructureDefinition/Extension|4.0.1"
          }
        ],
        "isModifier": false,
        "isSummary": false
      },
      {
        "id": "Extension.extension:statisticType.id",
        "path": "Extension.extension.id",
        "representation": [
          "xmlAttr"
        ],
        "short": "Unique id for inter-element referencing",
        "definition": "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Element.id",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
                "valueUrl": "string"
              }
            ],
            "code": "http://hl7.org/fhirpath/System.String"
          }
        ],
        "isModifier": false,
        "isSummary": false,
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          }
        ]
      },
      {
        "id": "Extension.extension:statisticType.extension",
        "path": "Extension.extension.extension",
        "slicing": {
          "discriminator": [
            {
              "type": "value",
              "path": "url"
            }
          ],
          "description": "Extensions are always sliced by (at least) url",
          "rules": "open"
        },
        "short": "Additional content defined by implementations",
        "definition": "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance  applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.",
        "comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
        "alias": [
          "extensions",
          "user content"
        ],
        "min": 0,
        "max": "*",
        "base": {
          "path": "Element.extension",
          "min": 0,
          "max": "*"
        },
        "type": [
          {
            "code": "Extension"
          }
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element|4.0.1"
          },
          {
            "key": "ext-1",
            "severity": "error",
            "human": "Must have either extensions or value[x], not both",
            "expression": "extension.exists() != value.exists()",
            "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
            "source": "http://hl7.org/fhir/StructureDefinition/Extension|4.0.1"
          }
        ],
        "isModifier": false,
        "isSummary": false,
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          }
        ]
      },
      {
        "id": "Extension.extension:statisticType.url",
        "path": "Extension.extension.url",
        "representation": [
          "xmlAttr"
        ],
        "short": "identifies the meaning of the extension",
        "definition": "Source of the definition for the extension code - a logical name or a URL.",
        "comment": "The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.",
        "min": 1,
        "max": "1",
        "base": {
          "path": "Extension.url",
          "min": 1,
          "max": "1"
        },
        "type": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
                "valueUrl": "uri"
              }
            ],
            "code": "http://hl7.org/fhirpath/System.String"
          }
        ],
        "fixedUri": "statisticType",
        "isModifier": false,
        "isSummary": false,
        "mapping": [
          {
            "identity": "rim",
            "map": "N/A"
          }
        ]
      },
      {
        "id": "Extension.extension:statisticType.value[x]",
        "path": "Extension.extension.value[x]",
        "short": "Type of statistic, e.g., relative risk",
        "definition": "Type of statistic, e.g., relative risk.",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Extension.value[x]",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "CodeableConcept"
          }
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element|4.0.1"
          }
        ],
        "isModifier": false,
        "isSummary": false,
        "binding": {
          "strength": "extensible",
          "valueSet": "http://hl7.org/fhir/uv/xver/ValueSet/R5-statistic-type-for-R4|0.1.0"
        },
        "mapping": [
          {
            "identity": "rim",
            "map": "N/A"
          }
        ]
      },
      {
        "id": "Extension.extension:category",
        "path": "Extension.extension",
        "sliceName": "category",
        "short": "R5: Associated category for categorical variable (new)",
        "definition": "R5: `Evidence.statistic.category` (new:CodeableConcept)",
        "comment": "Element `Evidence.statistic.category` is part of an existing definition because parent element `Evidence.statistic` requires a cross-version extension.\nElement `Evidence.statistic.category` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.category` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).\nSimple strings can be used for descriptive purposes. Exact matching to EvidenceVariable.category.name for the Evidence.variableDefinition[variableRole=measuredVariable].observed=Reference(EvidenceVariable) could facilitate validation within datasets.",
        "requirements": "Element `Evidence.statistic.category` is part of an existing definition because parent element `Evidence.statistic` requires a cross-version extension.\nElement `Evidence.statistic.category` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.category` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Element.extension",
          "min": 0,
          "max": "*"
        },
        "type": [
          {
            "code": "Extension"
          }
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element|4.0.1"
          },
          {
            "key": "ext-1",
            "severity": "error",
            "human": "Must have either extensions or value[x], not both",
            "expression": "extension.exists() != value.exists()",
            "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
            "source": "http://hl7.org/fhir/StructureDefinition/Extension|4.0.1"
          }
        ],
        "isModifier": false,
        "isSummary": false
      },
      {
        "id": "Extension.extension:category.id",
        "path": "Extension.extension.id",
        "representation": [
          "xmlAttr"
        ],
        "short": "Unique id for inter-element referencing",
        "definition": "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Element.id",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
                "valueUrl": "string"
              }
            ],
            "code": "http://hl7.org/fhirpath/System.String"
          }
        ],
        "isModifier": false,
        "isSummary": false,
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          }
        ]
      },
      {
        "id": "Extension.extension:category.extension",
        "path": "Extension.extension.extension",
        "slicing": {
          "discriminator": [
            {
              "type": "value",
              "path": "url"
            }
          ],
          "description": "Extensions are always sliced by (at least) url",
          "rules": "open"
        },
        "short": "Additional content defined by implementations",
        "definition": "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance  applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.",
        "comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
        "alias": [
          "extensions",
          "user content"
        ],
        "min": 0,
        "max": "*",
        "base": {
          "path": "Element.extension",
          "min": 0,
          "max": "*"
        },
        "type": [
          {
            "code": "Extension"
          }
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element|4.0.1"
          },
          {
            "key": "ext-1",
            "severity": "error",
            "human": "Must have either extensions or value[x], not both",
            "expression": "extension.exists() != value.exists()",
            "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
            "source": "http://hl7.org/fhir/StructureDefinition/Extension|4.0.1"
          }
        ],
        "isModifier": false,
        "isSummary": false,
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          }
        ]
      },
      {
        "id": "Extension.extension:category.url",
        "path": "Extension.extension.url",
        "representation": [
          "xmlAttr"
        ],
        "short": "identifies the meaning of the extension",
        "definition": "Source of the definition for the extension code - a logical name or a URL.",
        "comment": "The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.",
        "min": 1,
        "max": "1",
        "base": {
          "path": "Extension.url",
          "min": 1,
          "max": "1"
        },
        "type": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
                "valueUrl": "uri"
              }
            ],
            "code": "http://hl7.org/fhirpath/System.String"
          }
        ],
        "fixedUri": "category",
        "isModifier": false,
        "isSummary": false,
        "mapping": [
          {
            "identity": "rim",
            "map": "N/A"
          }
        ]
      },
      {
        "id": "Extension.extension:category.value[x]",
        "path": "Extension.extension.value[x]",
        "short": "Associated category for categorical variable",
        "definition": "When the measured variable is handled categorically, the category element is used to define which category the statistic is reporting.",
        "comment": "Simple strings can be used for descriptive purposes. Exact matching to EvidenceVariable.category.name for the Evidence.variableDefinition[variableRole=measuredVariable].observed=Reference(EvidenceVariable) could facilitate validation within datasets.",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Extension.value[x]",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "CodeableConcept"
          }
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element|4.0.1"
          }
        ],
        "isModifier": false,
        "isSummary": false,
        "mapping": [
          {
            "identity": "rim",
            "map": "N/A"
          }
        ]
      },
      {
        "id": "Extension.extension:quantity",
        "path": "Extension.extension",
        "sliceName": "quantity",
        "short": "R5: Statistic value (new)",
        "definition": "R5: `Evidence.statistic.quantity` (new:Quantity)",
        "comment": "Element `Evidence.statistic.quantity` is part of an existing definition because parent element `Evidence.statistic` requires a cross-version extension.\nElement `Evidence.statistic.quantity` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.quantity` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
        "requirements": "Element `Evidence.statistic.quantity` is part of an existing definition because parent element `Evidence.statistic` requires a cross-version extension.\nElement `Evidence.statistic.quantity` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.quantity` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Element.extension",
          "min": 0,
          "max": "*"
        },
        "type": [
          {
            "code": "Extension"
          }
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element|4.0.1"
          },
          {
            "key": "ext-1",
            "severity": "error",
            "human": "Must have either extensions or value[x], not both",
            "expression": "extension.exists() != value.exists()",
            "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
            "source": "http://hl7.org/fhir/StructureDefinition/Extension|4.0.1"
          }
        ],
        "isModifier": false,
        "isSummary": false
      },
      {
        "id": "Extension.extension:quantity.id",
        "path": "Extension.extension.id",
        "representation": [
          "xmlAttr"
        ],
        "short": "Unique id for inter-element referencing",
        "definition": "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Element.id",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
                "valueUrl": "string"
              }
            ],
            "code": "http://hl7.org/fhirpath/System.String"
          }
        ],
        "isModifier": false,
        "isSummary": false,
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          }
        ]
      },
      {
        "id": "Extension.extension:quantity.extension",
        "path": "Extension.extension.extension",
        "slicing": {
          "discriminator": [
            {
              "type": "value",
              "path": "url"
            }
          ],
          "description": "Extensions are always sliced by (at least) url",
          "rules": "open"
        },
        "short": "Additional content defined by implementations",
        "definition": "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance  applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.",
        "comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
        "alias": [
          "extensions",
          "user content"
        ],
        "min": 0,
        "max": "*",
        "base": {
          "path": "Element.extension",
          "min": 0,
          "max": "*"
        },
        "type": [
          {
            "code": "Extension"
          }
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element|4.0.1"
          },
          {
            "key": "ext-1",
            "severity": "error",
            "human": "Must have either extensions or value[x], not both",
            "expression": "extension.exists() != value.exists()",
            "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
            "source": "http://hl7.org/fhir/StructureDefinition/Extension|4.0.1"
          }
        ],
        "isModifier": false,
        "isSummary": false,
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          }
        ]
      },
      {
        "id": "Extension.extension:quantity.url",
        "path": "Extension.extension.url",
        "representation": [
          "xmlAttr"
        ],
        "short": "identifies the meaning of the extension",
        "definition": "Source of the definition for the extension code - a logical name or a URL.",
        "comment": "The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.",
        "min": 1,
        "max": "1",
        "base": {
          "path": "Extension.url",
          "min": 1,
          "max": "1"
        },
        "type": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
                "valueUrl": "uri"
              }
            ],
            "code": "http://hl7.org/fhirpath/System.String"
          }
        ],
        "fixedUri": "quantity",
        "isModifier": false,
        "isSummary": false,
        "mapping": [
          {
            "identity": "rim",
            "map": "N/A"
          }
        ]
      },
      {
        "id": "Extension.extension:quantity.value[x]",
        "path": "Extension.extension.value[x]",
        "short": "Statistic value",
        "definition": "Statistic value.",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Extension.value[x]",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "Quantity"
          }
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element|4.0.1"
          }
        ],
        "isModifier": false,
        "isSummary": false,
        "mapping": [
          {
            "identity": "rim",
            "map": "N/A"
          }
        ]
      },
      {
        "id": "Extension.extension:numberOfEvents",
        "path": "Extension.extension",
        "sliceName": "numberOfEvents",
        "short": "R5: The number of events associated with the statistic (new)",
        "definition": "R5: `Evidence.statistic.numberOfEvents` (new:unsignedInt)",
        "comment": "Element `Evidence.statistic.numberOfEvents` is part of an existing definition because parent element `Evidence.statistic` requires a cross-version extension.\nElement `Evidence.statistic.numberOfEvents` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.numberOfEvents` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).\nWhen the number of events is the statistic, use Evidence.statistic.quantity and set Evidence.statistic.type.coding.code=C25463 and Evidence.statistic.type.coding.display=Count. When the statistic is an Event Rate (where individual participants may have 2 or more events), use Evidence.statistic.numberOfEvents to record the total number of events rather than the number of participants with events.",
        "requirements": "Element `Evidence.statistic.numberOfEvents` is part of an existing definition because parent element `Evidence.statistic` requires a cross-version extension.\nElement `Evidence.statistic.numberOfEvents` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.numberOfEvents` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Element.extension",
          "min": 0,
          "max": "*"
        },
        "type": [
          {
            "code": "Extension"
          }
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element|4.0.1"
          },
          {
            "key": "ext-1",
            "severity": "error",
            "human": "Must have either extensions or value[x], not both",
            "expression": "extension.exists() != value.exists()",
            "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
            "source": "http://hl7.org/fhir/StructureDefinition/Extension|4.0.1"
          }
        ],
        "isModifier": false,
        "isSummary": false
      },
      {
        "id": "Extension.extension:numberOfEvents.id",
        "path": "Extension.extension.id",
        "representation": [
          "xmlAttr"
        ],
        "short": "Unique id for inter-element referencing",
        "definition": "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Element.id",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
                "valueUrl": "string"
              }
            ],
            "code": "http://hl7.org/fhirpath/System.String"
          }
        ],
        "isModifier": false,
        "isSummary": false,
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          }
        ]
      },
      {
        "id": "Extension.extension:numberOfEvents.extension",
        "path": "Extension.extension.extension",
        "slicing": {
          "discriminator": [
            {
              "type": "value",
              "path": "url"
            }
          ],
          "description": "Extensions are always sliced by (at least) url",
          "rules": "open"
        },
        "short": "Additional content defined by implementations",
        "definition": "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance  applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.",
        "comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
        "alias": [
          "extensions",
          "user content"
        ],
        "min": 0,
        "max": "*",
        "base": {
          "path": "Element.extension",
          "min": 0,
          "max": "*"
        },
        "type": [
          {
            "code": "Extension"
          }
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element|4.0.1"
          },
          {
            "key": "ext-1",
            "severity": "error",
            "human": "Must have either extensions or value[x], not both",
            "expression": "extension.exists() != value.exists()",
            "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
            "source": "http://hl7.org/fhir/StructureDefinition/Extension|4.0.1"
          }
        ],
        "isModifier": false,
        "isSummary": false,
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          }
        ]
      },
      {
        "id": "Extension.extension:numberOfEvents.url",
        "path": "Extension.extension.url",
        "representation": [
          "xmlAttr"
        ],
        "short": "identifies the meaning of the extension",
        "definition": "Source of the definition for the extension code - a logical name or a URL.",
        "comment": "The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.",
        "min": 1,
        "max": "1",
        "base": {
          "path": "Extension.url",
          "min": 1,
          "max": "1"
        },
        "type": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
                "valueUrl": "uri"
              }
            ],
            "code": "http://hl7.org/fhirpath/System.String"
          }
        ],
        "fixedUri": "numberOfEvents",
        "isModifier": false,
        "isSummary": false,
        "mapping": [
          {
            "identity": "rim",
            "map": "N/A"
          }
        ]
      },
      {
        "id": "Extension.extension:numberOfEvents.value[x]",
        "path": "Extension.extension.value[x]",
        "short": "The number of events associated with the statistic",
        "definition": "The number of events associated with the statistic, where the unit of analysis is different from numberAffected, sampleSize.knownDataCount and sampleSize.numberOfParticipants.",
        "comment": "When the number of events is the statistic, use Evidence.statistic.quantity and set Evidence.statistic.type.coding.code=C25463 and Evidence.statistic.type.coding.display=Count. When the statistic is an Event Rate (where individual participants may have 2 or more events), use Evidence.statistic.numberOfEvents to record the total number of events rather than the number of participants with events.",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Extension.value[x]",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "unsignedInt"
          }
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element|4.0.1"
          }
        ],
        "isModifier": false,
        "isSummary": false,
        "mapping": [
          {
            "identity": "rim",
            "map": "N/A"
          }
        ]
      },
      {
        "id": "Extension.extension:numberAffected",
        "path": "Extension.extension",
        "sliceName": "numberAffected",
        "short": "R5: The number of participants affected (new)",
        "definition": "R5: `Evidence.statistic.numberAffected` (new:unsignedInt)",
        "comment": "Element `Evidence.statistic.numberAffected` is part of an existing definition because parent element `Evidence.statistic` requires a cross-version extension.\nElement `Evidence.statistic.numberAffected` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.numberAffected` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).\nWhen the number affected is the statistic, use Evidence.statistic.quantity and set Evidence.statistic.type.coding.code=C25463 and Evidence.statistic.type.coding.display=Count. When the statistic is a Proportion, use Evidence.statistic.numberAffected and enter an integer as the value. When the statistic is an Event Rate (where individual participants may have 2 or more events), use Evidence.statistic.numberAffected to record the number of participants with events rather than the total number of events.",
        "requirements": "Element `Evidence.statistic.numberAffected` is part of an existing definition because parent element `Evidence.statistic` requires a cross-version extension.\nElement `Evidence.statistic.numberAffected` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.numberAffected` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Element.extension",
          "min": 0,
          "max": "*"
        },
        "type": [
          {
            "code": "Extension"
          }
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element|4.0.1"
          },
          {
            "key": "ext-1",
            "severity": "error",
            "human": "Must have either extensions or value[x], not both",
            "expression": "extension.exists() != value.exists()",
            "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
            "source": "http://hl7.org/fhir/StructureDefinition/Extension|4.0.1"
          }
        ],
        "isModifier": false,
        "isSummary": false
      },
      {
        "id": "Extension.extension:numberAffected.id",
        "path": "Extension.extension.id",
        "representation": [
          "xmlAttr"
        ],
        "short": "Unique id for inter-element referencing",
        "definition": "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Element.id",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
                "valueUrl": "string"
              }
            ],
            "code": "http://hl7.org/fhirpath/System.String"
          }
        ],
        "isModifier": false,
        "isSummary": false,
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          }
        ]
      },
      {
        "id": "Extension.extension:numberAffected.extension",
        "path": "Extension.extension.extension",
        "slicing": {
          "discriminator": [
            {
              "type": "value",
              "path": "url"
            }
          ],
          "description": "Extensions are always sliced by (at least) url",
          "rules": "open"
        },
        "short": "Additional content defined by implementations",
        "definition": "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance  applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.",
        "comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
        "alias": [
          "extensions",
          "user content"
        ],
        "min": 0,
        "max": "*",
        "base": {
          "path": "Element.extension",
          "min": 0,
          "max": "*"
        },
        "type": [
          {
            "code": "Extension"
          }
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element|4.0.1"
          },
          {
            "key": "ext-1",
            "severity": "error",
            "human": "Must have either extensions or value[x], not both",
            "expression": "extension.exists() != value.exists()",
            "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
            "source": "http://hl7.org/fhir/StructureDefinition/Extension|4.0.1"
          }
        ],
        "isModifier": false,
        "isSummary": false,
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          }
        ]
      },
      {
        "id": "Extension.extension:numberAffected.url",
        "path": "Extension.extension.url",
        "representation": [
          "xmlAttr"
        ],
        "short": "identifies the meaning of the extension",
        "definition": "Source of the definition for the extension code - a logical name or a URL.",
        "comment": "The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.",
        "min": 1,
        "max": "1",
        "base": {
          "path": "Extension.url",
          "min": 1,
          "max": "1"
        },
        "type": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
                "valueUrl": "uri"
              }
            ],
            "code": "http://hl7.org/fhirpath/System.String"
          }
        ],
        "fixedUri": "numberAffected",
        "isModifier": false,
        "isSummary": false,
        "mapping": [
          {
            "identity": "rim",
            "map": "N/A"
          }
        ]
      },
      {
        "id": "Extension.extension:numberAffected.value[x]",
        "path": "Extension.extension.value[x]",
        "short": "The number of participants affected",
        "definition": "The number of participants affected where the unit of analysis is the same as sampleSize.knownDataCount and sampleSize.numberOfParticipants.",
        "comment": "When the number affected is the statistic, use Evidence.statistic.quantity and set Evidence.statistic.type.coding.code=C25463 and Evidence.statistic.type.coding.display=Count. When the statistic is a Proportion, use Evidence.statistic.numberAffected and enter an integer as the value. When the statistic is an Event Rate (where individual participants may have 2 or more events), use Evidence.statistic.numberAffected to record the number of participants with events rather than the total number of events.",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Extension.value[x]",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "unsignedInt"
          }
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element|4.0.1"
          }
        ],
        "isModifier": false,
        "isSummary": false,
        "mapping": [
          {
            "identity": "rim",
            "map": "N/A"
          }
        ]
      },
      {
        "id": "Extension.extension:sampleSize",
        "path": "Extension.extension",
        "sliceName": "sampleSize",
        "short": "R5: Number of samples in the statistic (new)",
        "definition": "R5: `Evidence.statistic.sampleSize` (new:BackboneElement)",
        "comment": "Element `Evidence.statistic.sampleSize` is part of an existing definition because parent element `Evidence.statistic` requires a cross-version extension.\nElement `Evidence.statistic.sampleSize` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.sampleSize` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
        "requirements": "Element `Evidence.statistic.sampleSize` is part of an existing definition because parent element `Evidence.statistic` requires a cross-version extension.\nElement `Evidence.statistic.sampleSize` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.sampleSize` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Element.extension",
          "min": 0,
          "max": "*"
        },
        "type": [
          {
            "code": "Extension"
          }
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element|4.0.1"
          },
          {
            "key": "ext-1",
            "severity": "error",
            "human": "Must have either extensions or value[x], not both",
            "expression": "extension.exists() != value.exists()",
            "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
            "source": "http://hl7.org/fhir/StructureDefinition/Extension|4.0.1"
          }
        ],
        "isModifier": false,
        "isSummary": false
      },
      {
        "id": "Extension.extension:sampleSize.id",
        "path": "Extension.extension.id",
        "representation": [
          "xmlAttr"
        ],
        "short": "Unique id for inter-element referencing",
        "definition": "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Element.id",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
                "valueUrl": "string"
              }
            ],
            "code": "http://hl7.org/fhirpath/System.String"
          }
        ],
        "isModifier": false,
        "isSummary": false,
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          }
        ]
      },
      {
        "id": "Extension.extension:sampleSize.extension",
        "path": "Extension.extension.extension",
        "slicing": {
          "discriminator": [
            {
              "type": "value",
              "path": "url"
            }
          ],
          "description": "Extensions are always sliced by (at least) url",
          "ordered": false,
          "rules": "open"
        },
        "short": "Extension",
        "definition": "An Extension",
        "min": 0,
        "max": "*",
        "base": {
          "path": "Element.extension",
          "min": 0,
          "max": "*"
        },
        "type": [
          {
            "code": "Extension"
          }
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element|4.0.1"
          },
          {
            "key": "ext-1",
            "severity": "error",
            "human": "Must have either extensions or value[x], not both",
            "expression": "extension.exists() != value.exists()",
            "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
            "source": "http://hl7.org/fhir/StructureDefinition/Extension|4.0.1"
          }
        ],
        "isModifier": false,
        "isSummary": false
      },
      {
        "id": "Extension.extension:sampleSize.extension:description",
        "path": "Extension.extension.extension",
        "sliceName": "description",
        "short": "R5: Textual description of sample size for statistic (new)",
        "definition": "R5: `Evidence.statistic.sampleSize.description` (new:markdown)",
        "comment": "Element `Evidence.statistic.sampleSize.description` is part of an existing definition because parent element `Evidence.statistic.sampleSize` requires a cross-version extension.\nElement `Evidence.statistic.sampleSize.description` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.sampleSize.description` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
        "requirements": "Element `Evidence.statistic.sampleSize.description` is part of an existing definition because parent element `Evidence.statistic.sampleSize` requires a cross-version extension.\nElement `Evidence.statistic.sampleSize.description` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.sampleSize.description` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Element.extension",
          "min": 0,
          "max": "*"
        },
        "type": [
          {
            "code": "Extension"
          }
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element|4.0.1"
          },
          {
            "key": "ext-1",
            "severity": "error",
            "human": "Must have either extensions or value[x], not both",
            "expression": "extension.exists() != value.exists()",
            "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
            "source": "http://hl7.org/fhir/StructureDefinition/Extension|4.0.1"
          }
        ],
        "isModifier": false,
        "isSummary": false
      },
      {
        "id": "Extension.extension:sampleSize.extension:description.id",
        "path": "Extension.extension.extension.id",
        "representation": [
          "xmlAttr"
        ],
        "short": "Unique id for inter-element referencing",
        "definition": "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Element.id",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
                "valueUrl": "string"
              }
            ],
            "code": "http://hl7.org/fhirpath/System.String"
          }
        ],
        "isModifier": false,
        "isSummary": false,
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          }
        ]
      },
      {
        "id": "Extension.extension:sampleSize.extension:description.extension",
        "path": "Extension.extension.extension.extension",
        "slicing": {
          "discriminator": [
            {
              "type": "value",
              "path": "url"
            }
          ],
          "description": "Extensions are always sliced by (at least) url",
          "rules": "open"
        },
        "short": "Additional content defined by implementations",
        "definition": "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance  applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.",
        "comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
        "alias": [
          "extensions",
          "user content"
        ],
        "min": 0,
        "max": "*",
        "base": {
          "path": "Element.extension",
          "min": 0,
          "max": "*"
        },
        "type": [
          {
            "code": "Extension"
          }
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element|4.0.1"
          },
          {
            "key": "ext-1",
            "severity": "error",
            "human": "Must have either extensions or value[x], not both",
            "expression": "extension.exists() != value.exists()",
            "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
            "source": "http://hl7.org/fhir/StructureDefinition/Extension|4.0.1"
          }
        ],
        "isModifier": false,
        "isSummary": false,
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          }
        ]
      },
      {
        "id": "Extension.extension:sampleSize.extension:description.url",
        "path": "Extension.extension.extension.url",
        "representation": [
          "xmlAttr"
        ],
        "short": "identifies the meaning of the extension",
        "definition": "Source of the definition for the extension code - a logical name or a URL.",
        "comment": "The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.",
        "min": 1,
        "max": "1",
        "base": {
          "path": "Extension.url",
          "min": 1,
          "max": "1"
        },
        "type": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
                "valueUrl": "uri"
              }
            ],
            "code": "http://hl7.org/fhirpath/System.String"
          }
        ],
        "fixedUri": "description",
        "isModifier": false,
        "isSummary": false,
        "mapping": [
          {
            "identity": "rim",
            "map": "N/A"
          }
        ]
      },
      {
        "id": "Extension.extension:sampleSize.extension:description.value[x]",
        "path": "Extension.extension.extension.value[x]",
        "short": "Textual description of sample size for statistic",
        "definition": "Human-readable summary of population sample size.",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Extension.value[x]",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "markdown"
          }
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element|4.0.1"
          }
        ],
        "isModifier": false,
        "isSummary": false,
        "mapping": [
          {
            "identity": "rim",
            "map": "N/A"
          }
        ]
      },
      {
        "id": "Extension.extension:sampleSize.extension:note",
        "path": "Extension.extension.extension",
        "sliceName": "note",
        "short": "R5: Footnote or explanatory note about the sample size (new)",
        "definition": "R5: `Evidence.statistic.sampleSize.note` (new:Annotation)",
        "comment": "Element `Evidence.statistic.sampleSize.note` is part of an existing definition because parent element `Evidence.statistic.sampleSize` requires a cross-version extension.\nElement `Evidence.statistic.sampleSize.note` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.sampleSize.note` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
        "requirements": "Element `Evidence.statistic.sampleSize.note` is part of an existing definition because parent element `Evidence.statistic.sampleSize` requires a cross-version extension.\nElement `Evidence.statistic.sampleSize.note` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.sampleSize.note` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
        "min": 0,
        "max": "*",
        "base": {
          "path": "Element.extension",
          "min": 0,
          "max": "*"
        },
        "type": [
          {
            "code": "Extension"
          }
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element|4.0.1"
          },
          {
            "key": "ext-1",
            "severity": "error",
            "human": "Must have either extensions or value[x], not both",
            "expression": "extension.exists() != value.exists()",
            "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
            "source": "http://hl7.org/fhir/StructureDefinition/Extension|4.0.1"
          }
        ],
        "isModifier": false,
        "isSummary": false
      },
      {
        "id": "Extension.extension:sampleSize.extension:note.id",
        "path": "Extension.extension.extension.id",
        "representation": [
          "xmlAttr"
        ],
        "short": "Unique id for inter-element referencing",
        "definition": "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Element.id",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
                "valueUrl": "string"
              }
            ],
            "code": "http://hl7.org/fhirpath/System.String"
          }
        ],
        "isModifier": false,
        "isSummary": false,
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          }
        ]
      },
      {
        "id": "Extension.extension:sampleSize.extension:note.extension",
        "path": "Extension.extension.extension.extension",
        "slicing": {
          "discriminator": [
            {
              "type": "value",
              "path": "url"
            }
          ],
          "description": "Extensions are always sliced by (at least) url",
          "rules": "open"
        },
        "short": "Additional content defined by implementations",
        "definition": "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance  applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.",
        "comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
        "alias": [
          "extensions",
          "user content"
        ],
        "min": 0,
        "max": "*",
        "base": {
          "path": "Element.extension",
          "min": 0,
          "max": "*"
        },
        "type": [
          {
            "code": "Extension"
          }
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element|4.0.1"
          },
          {
            "key": "ext-1",
            "severity": "error",
            "human": "Must have either extensions or value[x], not both",
            "expression": "extension.exists() != value.exists()",
            "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
            "source": "http://hl7.org/fhir/StructureDefinition/Extension|4.0.1"
          }
        ],
        "isModifier": false,
        "isSummary": false,
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          }
        ]
      },
      {
        "id": "Extension.extension:sampleSize.extension:note.url",
        "path": "Extension.extension.extension.url",
        "representation": [
          "xmlAttr"
        ],
        "short": "identifies the meaning of the extension",
        "definition": "Source of the definition for the extension code - a logical name or a URL.",
        "comment": "The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.",
        "min": 1,
        "max": "1",
        "base": {
          "path": "Extension.url",
          "min": 1,
          "max": "1"
        },
        "type": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
                "valueUrl": "uri"
              }
            ],
            "code": "http://hl7.org/fhirpath/System.String"
          }
        ],
        "fixedUri": "note",
        "isModifier": false,
        "isSummary": false,
        "mapping": [
          {
            "identity": "rim",
            "map": "N/A"
          }
        ]
      },
      {
        "id": "Extension.extension:sampleSize.extension:note.value[x]",
        "path": "Extension.extension.extension.value[x]",
        "short": "Footnote or explanatory note about the sample size",
        "definition": "Footnote or explanatory note about the sample size.",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Extension.value[x]",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "Annotation"
          }
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element|4.0.1"
          }
        ],
        "isModifier": false,
        "isSummary": false,
        "mapping": [
          {
            "identity": "rim",
            "map": "N/A"
          }
        ]
      },
      {
        "id": "Extension.extension:sampleSize.extension:numberOfStudies",
        "path": "Extension.extension.extension",
        "sliceName": "numberOfStudies",
        "short": "R5: Number of contributing studies (new)",
        "definition": "R5: `Evidence.statistic.sampleSize.numberOfStudies` (new:unsignedInt)",
        "comment": "Element `Evidence.statistic.sampleSize.numberOfStudies` is part of an existing definition because parent element `Evidence.statistic.sampleSize` requires a cross-version extension.\nElement `Evidence.statistic.sampleSize.numberOfStudies` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.sampleSize.numberOfStudies` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
        "requirements": "Element `Evidence.statistic.sampleSize.numberOfStudies` is part of an existing definition because parent element `Evidence.statistic.sampleSize` requires a cross-version extension.\nElement `Evidence.statistic.sampleSize.numberOfStudies` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.sampleSize.numberOfStudies` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Element.extension",
          "min": 0,
          "max": "*"
        },
        "type": [
          {
            "code": "Extension"
          }
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element|4.0.1"
          },
          {
            "key": "ext-1",
            "severity": "error",
            "human": "Must have either extensions or value[x], not both",
            "expression": "extension.exists() != value.exists()",
            "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
            "source": "http://hl7.org/fhir/StructureDefinition/Extension|4.0.1"
          }
        ],
        "isModifier": false,
        "isSummary": false
      },
      {
        "id": "Extension.extension:sampleSize.extension:numberOfStudies.id",
        "path": "Extension.extension.extension.id",
        "representation": [
          "xmlAttr"
        ],
        "short": "Unique id for inter-element referencing",
        "definition": "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Element.id",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
                "valueUrl": "string"
              }
            ],
            "code": "http://hl7.org/fhirpath/System.String"
          }
        ],
        "isModifier": false,
        "isSummary": false,
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          }
        ]
      },
      {
        "id": "Extension.extension:sampleSize.extension:numberOfStudies.extension",
        "path": "Extension.extension.extension.extension",
        "slicing": {
          "discriminator": [
            {
              "type": "value",
              "path": "url"
            }
          ],
          "description": "Extensions are always sliced by (at least) url",
          "rules": "open"
        },
        "short": "Additional content defined by implementations",
        "definition": "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance  applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.",
        "comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
        "alias": [
          "extensions",
          "user content"
        ],
        "min": 0,
        "max": "*",
        "base": {
          "path": "Element.extension",
          "min": 0,
          "max": "*"
        },
        "type": [
          {
            "code": "Extension"
          }
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element|4.0.1"
          },
          {
            "key": "ext-1",
            "severity": "error",
            "human": "Must have either extensions or value[x], not both",
            "expression": "extension.exists() != value.exists()",
            "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
            "source": "http://hl7.org/fhir/StructureDefinition/Extension|4.0.1"
          }
        ],
        "isModifier": false,
        "isSummary": false,
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          }
        ]
      },
      {
        "id": "Extension.extension:sampleSize.extension:numberOfStudies.url",
        "path": "Extension.extension.extension.url",
        "representation": [
          "xmlAttr"
        ],
        "short": "identifies the meaning of the extension",
        "definition": "Source of the definition for the extension code - a logical name or a URL.",
        "comment": "The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.",
        "min": 1,
        "max": "1",
        "base": {
          "path": "Extension.url",
          "min": 1,
          "max": "1"
        },
        "type": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
                "valueUrl": "uri"
              }
            ],
            "code": "http://hl7.org/fhirpath/System.String"
          }
        ],
        "fixedUri": "numberOfStudies",
        "isModifier": false,
        "isSummary": false,
        "mapping": [
          {
            "identity": "rim",
            "map": "N/A"
          }
        ]
      },
      {
        "id": "Extension.extension:sampleSize.extension:numberOfStudies.value[x]",
        "path": "Extension.extension.extension.value[x]",
        "short": "Number of contributing studies",
        "definition": "Number of participants in the population.",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Extension.value[x]",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "unsignedInt"
          }
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element|4.0.1"
          }
        ],
        "isModifier": false,
        "isSummary": false,
        "mapping": [
          {
            "identity": "rim",
            "map": "N/A"
          }
        ]
      },
      {
        "id": "Extension.extension:sampleSize.extension:numberOfParticipants",
        "path": "Extension.extension.extension",
        "sliceName": "numberOfParticipants",
        "short": "R5: Cumulative number of participants (new)",
        "definition": "R5: `Evidence.statistic.sampleSize.numberOfParticipants` (new:unsignedInt)",
        "comment": "Element `Evidence.statistic.sampleSize.numberOfParticipants` is part of an existing definition because parent element `Evidence.statistic.sampleSize` requires a cross-version extension.\nElement `Evidence.statistic.sampleSize.numberOfParticipants` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.sampleSize.numberOfParticipants` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
        "requirements": "Element `Evidence.statistic.sampleSize.numberOfParticipants` is part of an existing definition because parent element `Evidence.statistic.sampleSize` requires a cross-version extension.\nElement `Evidence.statistic.sampleSize.numberOfParticipants` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.sampleSize.numberOfParticipants` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Element.extension",
          "min": 0,
          "max": "*"
        },
        "type": [
          {
            "code": "Extension"
          }
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element|4.0.1"
          },
          {
            "key": "ext-1",
            "severity": "error",
            "human": "Must have either extensions or value[x], not both",
            "expression": "extension.exists() != value.exists()",
            "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
            "source": "http://hl7.org/fhir/StructureDefinition/Extension|4.0.1"
          }
        ],
        "isModifier": false,
        "isSummary": false
      },
      {
        "id": "Extension.extension:sampleSize.extension:numberOfParticipants.id",
        "path": "Extension.extension.extension.id",
        "representation": [
          "xmlAttr"
        ],
        "short": "Unique id for inter-element referencing",
        "definition": "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Element.id",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
                "valueUrl": "string"
              }
            ],
            "code": "http://hl7.org/fhirpath/System.String"
          }
        ],
        "isModifier": false,
        "isSummary": false,
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          }
        ]
      },
      {
        "id": "Extension.extension:sampleSize.extension:numberOfParticipants.extension",
        "path": "Extension.extension.extension.extension",
        "slicing": {
          "discriminator": [
            {
              "type": "value",
              "path": "url"
            }
          ],
          "description": "Extensions are always sliced by (at least) url",
          "rules": "open"
        },
        "short": "Additional content defined by implementations",
        "definition": "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance  applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.",
        "comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
        "alias": [
          "extensions",
          "user content"
        ],
        "min": 0,
        "max": "*",
        "base": {
          "path": "Element.extension",
          "min": 0,
          "max": "*"
        },
        "type": [
          {
            "code": "Extension"
          }
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element|4.0.1"
          },
          {
            "key": "ext-1",
            "severity": "error",
            "human": "Must have either extensions or value[x], not both",
            "expression": "extension.exists() != value.exists()",
            "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
            "source": "http://hl7.org/fhir/StructureDefinition/Extension|4.0.1"
          }
        ],
        "isModifier": false,
        "isSummary": false,
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          }
        ]
      },
      {
        "id": "Extension.extension:sampleSize.extension:numberOfParticipants.url",
        "path": "Extension.extension.extension.url",
        "representation": [
          "xmlAttr"
        ],
        "short": "identifies the meaning of the extension",
        "definition": "Source of the definition for the extension code - a logical name or a URL.",
        "comment": "The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.",
        "min": 1,
        "max": "1",
        "base": {
          "path": "Extension.url",
          "min": 1,
          "max": "1"
        },
        "type": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
                "valueUrl": "uri"
              }
            ],
            "code": "http://hl7.org/fhirpath/System.String"
          }
        ],
        "fixedUri": "numberOfParticipants",
        "isModifier": false,
        "isSummary": false,
        "mapping": [
          {
            "identity": "rim",
            "map": "N/A"
          }
        ]
      },
      {
        "id": "Extension.extension:sampleSize.extension:numberOfParticipants.value[x]",
        "path": "Extension.extension.extension.value[x]",
        "short": "Cumulative number of participants",
        "definition": "A human-readable string to clarify or explain concepts about the sample size.",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Extension.value[x]",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "unsignedInt"
          }
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element|4.0.1"
          }
        ],
        "isModifier": false,
        "isSummary": false,
        "mapping": [
          {
            "identity": "rim",
            "map": "N/A"
          }
        ]
      },
      {
        "id": "Extension.extension:sampleSize.extension:knownDataCount",
        "path": "Extension.extension.extension",
        "sliceName": "knownDataCount",
        "short": "R5: Number of participants with known results for measured variables (new)",
        "definition": "R5: `Evidence.statistic.sampleSize.knownDataCount` (new:unsignedInt)",
        "comment": "Element `Evidence.statistic.sampleSize.knownDataCount` is part of an existing definition because parent element `Evidence.statistic.sampleSize` requires a cross-version extension.\nElement `Evidence.statistic.sampleSize.knownDataCount` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.sampleSize.knownDataCount` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
        "requirements": "Element `Evidence.statistic.sampleSize.knownDataCount` is part of an existing definition because parent element `Evidence.statistic.sampleSize` requires a cross-version extension.\nElement `Evidence.statistic.sampleSize.knownDataCount` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.sampleSize.knownDataCount` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Element.extension",
          "min": 0,
          "max": "*"
        },
        "type": [
          {
            "code": "Extension"
          }
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element|4.0.1"
          },
          {
            "key": "ext-1",
            "severity": "error",
            "human": "Must have either extensions or value[x], not both",
            "expression": "extension.exists() != value.exists()",
            "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
            "source": "http://hl7.org/fhir/StructureDefinition/Extension|4.0.1"
          }
        ],
        "isModifier": false,
        "isSummary": false
      },
      {
        "id": "Extension.extension:sampleSize.extension:knownDataCount.id",
        "path": "Extension.extension.extension.id",
        "representation": [
          "xmlAttr"
        ],
        "short": "Unique id for inter-element referencing",
        "definition": "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Element.id",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
                "valueUrl": "string"
              }
            ],
            "code": "http://hl7.org/fhirpath/System.String"
          }
        ],
        "isModifier": false,
        "isSummary": false,
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          }
        ]
      },
      {
        "id": "Extension.extension:sampleSize.extension:knownDataCount.extension",
        "path": "Extension.extension.extension.extension",
        "slicing": {
          "discriminator": [
            {
              "type": "value",
              "path": "url"
            }
          ],
          "description": "Extensions are always sliced by (at least) url",
          "rules": "open"
        },
        "short": "Additional content defined by implementations",
        "definition": "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance  applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.",
        "comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
        "alias": [
          "extensions",
          "user content"
        ],
        "min": 0,
        "max": "*",
        "base": {
          "path": "Element.extension",
          "min": 0,
          "max": "*"
        },
        "type": [
          {
            "code": "Extension"
          }
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element|4.0.1"
          },
          {
            "key": "ext-1",
            "severity": "error",
            "human": "Must have either extensions or value[x], not both",
            "expression": "extension.exists() != value.exists()",
            "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
            "source": "http://hl7.org/fhir/StructureDefinition/Extension|4.0.1"
          }
        ],
        "isModifier": false,
        "isSummary": false,
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          }
        ]
      },
      {
        "id": "Extension.extension:sampleSize.extension:knownDataCount.url",
        "path": "Extension.extension.extension.url",
        "representation": [
          "xmlAttr"
        ],
        "short": "identifies the meaning of the extension",
        "definition": "Source of the definition for the extension code - a logical name or a URL.",
        "comment": "The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.",
        "min": 1,
        "max": "1",
        "base": {
          "path": "Extension.url",
          "min": 1,
          "max": "1"
        },
        "type": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
                "valueUrl": "uri"
              }
            ],
            "code": "http://hl7.org/fhirpath/System.String"
          }
        ],
        "fixedUri": "knownDataCount",
        "isModifier": false,
        "isSummary": false,
        "mapping": [
          {
            "identity": "rim",
            "map": "N/A"
          }
        ]
      },
      {
        "id": "Extension.extension:sampleSize.extension:knownDataCount.value[x]",
        "path": "Extension.extension.extension.value[x]",
        "short": "Number of participants with known results for measured variables",
        "definition": "Number of participants with known results for measured variables.",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Extension.value[x]",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "unsignedInt"
          }
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element|4.0.1"
          }
        ],
        "isModifier": false,
        "isSummary": false,
        "mapping": [
          {
            "identity": "rim",
            "map": "N/A"
          }
        ]
      },
      {
        "id": "Extension.extension:sampleSize.url",
        "path": "Extension.extension.url",
        "representation": [
          "xmlAttr"
        ],
        "short": "identifies the meaning of the extension",
        "definition": "Source of the definition for the extension code - a logical name or a URL.",
        "comment": "The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.",
        "min": 1,
        "max": "1",
        "base": {
          "path": "Extension.url",
          "min": 1,
          "max": "1"
        },
        "type": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
                "valueUrl": "uri"
              }
            ],
            "code": "http://hl7.org/fhirpath/System.String"
          }
        ],
        "fixedUri": "sampleSize",
        "isModifier": false,
        "isSummary": false,
        "mapping": [
          {
            "identity": "rim",
            "map": "N/A"
          }
        ]
      },
      {
        "id": "Extension.extension:sampleSize.value[x]",
        "path": "Extension.extension.value[x]",
        "short": "Value of extension",
        "definition": "Value of extension - must be one of a constrained set of the data types (see [Extensibility](http://hl7.org/fhir/R4/extensibility.html) for a list).",
        "min": 0,
        "max": "0",
        "base": {
          "path": "Extension.value[x]",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "base64Binary"
          },
          {
            "code": "boolean"
          },
          {
            "code": "canonical"
          },
          {
            "code": "code"
          },
          {
            "code": "date"
          },
          {
            "code": "dateTime"
          },
          {
            "code": "decimal"
          },
          {
            "code": "id"
          },
          {
            "code": "instant"
          },
          {
            "code": "integer"
          },
          {
            "code": "markdown"
          },
          {
            "code": "oid"
          },
          {
            "code": "positiveInt"
          },
          {
            "code": "string"
          },
          {
            "code": "time"
          },
          {
            "code": "unsignedInt"
          },
          {
            "code": "uri"
          },
          {
            "code": "url"
          },
          {
            "code": "uuid"
          },
          {
            "code": "Address"
          },
          {
            "code": "Age"
          },
          {
            "code": "Annotation"
          },
          {
            "code": "Attachment"
          },
          {
            "code": "CodeableConcept"
          },
          {
            "code": "Coding"
          },
          {
            "code": "ContactPoint"
          },
          {
            "code": "Count"
          },
          {
            "code": "Distance"
          },
          {
            "code": "Duration"
          },
          {
            "code": "HumanName"
          },
          {
            "code": "Identifier"
          },
          {
            "code": "Money"
          },
          {
            "code": "Period"
          },
          {
            "code": "Quantity"
          },
          {
            "code": "Range"
          },
          {
            "code": "Ratio"
          },
          {
            "code": "Reference"
          },
          {
            "code": "SampledData"
          },
          {
            "code": "Signature"
          },
          {
            "code": "Timing"
          },
          {
            "code": "ContactDetail"
          },
          {
            "code": "Contributor"
          },
          {
            "code": "DataRequirement"
          },
          {
            "code": "Expression"
          },
          {
            "code": "ParameterDefinition"
          },
          {
            "code": "RelatedArtifact"
          },
          {
            "code": "TriggerDefinition"
          },
          {
            "code": "UsageContext"
          },
          {
            "code": "Dosage"
          },
          {
            "code": "Meta"
          }
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element|4.0.1"
          }
        ],
        "isModifier": false,
        "isSummary": false,
        "mapping": [
          {
            "identity": "rim",
            "map": "N/A"
          }
        ]
      },
      {
        "id": "Extension.extension:attributeEstimate",
        "path": "Extension.extension",
        "sliceName": "attributeEstimate",
        "short": "R5: An attribute of the Statistic (new)",
        "definition": "R5: `Evidence.statistic.attributeEstimate` (new:BackboneElement)",
        "comment": "Element `Evidence.statistic.attributeEstimate` is part of an existing definition because parent element `Evidence.statistic` requires a cross-version extension.\nElement `Evidence.statistic.attributeEstimate` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.attributeEstimate` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
        "requirements": "Element `Evidence.statistic.attributeEstimate` is part of an existing definition because parent element `Evidence.statistic` requires a cross-version extension.\nElement `Evidence.statistic.attributeEstimate` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.attributeEstimate` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).\nCreating extension because element `Evidence.statistic.attributeEstimate` is a content reference and requires an extesion definition.",
        "min": 0,
        "max": "*",
        "base": {
          "path": "Element.extension",
          "min": 0,
          "max": "*"
        },
        "type": [
          {
            "code": "Extension"
          }
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element|4.0.1"
          },
          {
            "key": "ext-1",
            "severity": "error",
            "human": "Must have either extensions or value[x], not both",
            "expression": "extension.exists() != value.exists()",
            "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
            "source": "http://hl7.org/fhir/StructureDefinition/Extension|4.0.1"
          }
        ],
        "isModifier": false,
        "isSummary": false
      },
      {
        "id": "Extension.extension:attributeEstimate.id",
        "path": "Extension.extension.id",
        "representation": [
          "xmlAttr"
        ],
        "short": "Unique id for inter-element referencing",
        "definition": "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Element.id",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
                "valueUrl": "string"
              }
            ],
            "code": "http://hl7.org/fhirpath/System.String"
          }
        ],
        "isModifier": false,
        "isSummary": false,
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          }
        ]
      },
      {
        "id": "Extension.extension:attributeEstimate.extension",
        "path": "Extension.extension.extension",
        "slicing": {
          "discriminator": [
            {
              "type": "value",
              "path": "url"
            }
          ],
          "description": "Extensions are always sliced by (at least) url",
          "ordered": false,
          "rules": "open"
        },
        "short": "Extension",
        "definition": "An Extension",
        "min": 0,
        "max": "*",
        "base": {
          "path": "Element.extension",
          "min": 0,
          "max": "*"
        },
        "type": [
          {
            "code": "Extension"
          }
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element|4.0.1"
          },
          {
            "key": "ext-1",
            "severity": "error",
            "human": "Must have either extensions or value[x], not both",
            "expression": "extension.exists() != value.exists()",
            "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
            "source": "http://hl7.org/fhir/StructureDefinition/Extension|4.0.1"
          }
        ],
        "isModifier": false,
        "isSummary": false
      },
      {
        "id": "Extension.extension:attributeEstimate.extension:description",
        "path": "Extension.extension.extension",
        "sliceName": "description",
        "short": "R5: Textual description of the attribute estimate (new)",
        "definition": "R5: `Evidence.statistic.attributeEstimate.description` (new:markdown)",
        "comment": "Element `Evidence.statistic.attributeEstimate.description` is part of an existing definition because parent element `Evidence.statistic.attributeEstimate` requires a cross-version extension.\nElement `Evidence.statistic.attributeEstimate.description` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.attributeEstimate.description` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
        "requirements": "Element `Evidence.statistic.attributeEstimate.description` is part of an existing definition because parent element `Evidence.statistic.attributeEstimate` requires a cross-version extension.\nElement `Evidence.statistic.attributeEstimate.description` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.attributeEstimate.description` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Element.extension",
          "min": 0,
          "max": "*"
        },
        "type": [
          {
            "code": "Extension"
          }
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element|4.0.1"
          },
          {
            "key": "ext-1",
            "severity": "error",
            "human": "Must have either extensions or value[x], not both",
            "expression": "extension.exists() != value.exists()",
            "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
            "source": "http://hl7.org/fhir/StructureDefinition/Extension|4.0.1"
          }
        ],
        "isModifier": false,
        "isSummary": false
      },
      {
        "id": "Extension.extension:attributeEstimate.extension:description.id",
        "path": "Extension.extension.extension.id",
        "representation": [
          "xmlAttr"
        ],
        "short": "Unique id for inter-element referencing",
        "definition": "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Element.id",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
                "valueUrl": "string"
              }
            ],
            "code": "http://hl7.org/fhirpath/System.String"
          }
        ],
        "isModifier": false,
        "isSummary": false,
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          }
        ]
      },
      {
        "id": "Extension.extension:attributeEstimate.extension:description.extension",
        "path": "Extension.extension.extension.extension",
        "slicing": {
          "discriminator": [
            {
              "type": "value",
              "path": "url"
            }
          ],
          "description": "Extensions are always sliced by (at least) url",
          "rules": "open"
        },
        "short": "Additional content defined by implementations",
        "definition": "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance  applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.",
        "comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
        "alias": [
          "extensions",
          "user content"
        ],
        "min": 0,
        "max": "*",
        "base": {
          "path": "Element.extension",
          "min": 0,
          "max": "*"
        },
        "type": [
          {
            "code": "Extension"
          }
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element|4.0.1"
          },
          {
            "key": "ext-1",
            "severity": "error",
            "human": "Must have either extensions or value[x], not both",
            "expression": "extension.exists() != value.exists()",
            "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
            "source": "http://hl7.org/fhir/StructureDefinition/Extension|4.0.1"
          }
        ],
        "isModifier": false,
        "isSummary": false,
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          }
        ]
      },
      {
        "id": "Extension.extension:attributeEstimate.extension:description.url",
        "path": "Extension.extension.extension.url",
        "representation": [
          "xmlAttr"
        ],
        "short": "identifies the meaning of the extension",
        "definition": "Source of the definition for the extension code - a logical name or a URL.",
        "comment": "The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.",
        "min": 1,
        "max": "1",
        "base": {
          "path": "Extension.url",
          "min": 1,
          "max": "1"
        },
        "type": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
                "valueUrl": "uri"
              }
            ],
            "code": "http://hl7.org/fhirpath/System.String"
          }
        ],
        "fixedUri": "description",
        "isModifier": false,
        "isSummary": false,
        "mapping": [
          {
            "identity": "rim",
            "map": "N/A"
          }
        ]
      },
      {
        "id": "Extension.extension:attributeEstimate.extension:description.value[x]",
        "path": "Extension.extension.extension.value[x]",
        "short": "Textual description of the attribute estimate",
        "definition": "Human-readable summary of the estimate.",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Extension.value[x]",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "markdown"
          }
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element|4.0.1"
          }
        ],
        "isModifier": false,
        "isSummary": false,
        "mapping": [
          {
            "identity": "rim",
            "map": "N/A"
          }
        ]
      },
      {
        "id": "Extension.extension:attributeEstimate.extension:note",
        "path": "Extension.extension.extension",
        "sliceName": "note",
        "short": "R5: Footnote or explanatory note about the estimate (new)",
        "definition": "R5: `Evidence.statistic.attributeEstimate.note` (new:Annotation)",
        "comment": "Element `Evidence.statistic.attributeEstimate.note` is part of an existing definition because parent element `Evidence.statistic.attributeEstimate` requires a cross-version extension.\nElement `Evidence.statistic.attributeEstimate.note` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.attributeEstimate.note` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
        "requirements": "Element `Evidence.statistic.attributeEstimate.note` is part of an existing definition because parent element `Evidence.statistic.attributeEstimate` requires a cross-version extension.\nElement `Evidence.statistic.attributeEstimate.note` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.attributeEstimate.note` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
        "min": 0,
        "max": "*",
        "base": {
          "path": "Element.extension",
          "min": 0,
          "max": "*"
        },
        "type": [
          {
            "code": "Extension"
          }
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element|4.0.1"
          },
          {
            "key": "ext-1",
            "severity": "error",
            "human": "Must have either extensions or value[x], not both",
            "expression": "extension.exists() != value.exists()",
            "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
            "source": "http://hl7.org/fhir/StructureDefinition/Extension|4.0.1"
          }
        ],
        "isModifier": false,
        "isSummary": false
      },
      {
        "id": "Extension.extension:attributeEstimate.extension:note.id",
        "path": "Extension.extension.extension.id",
        "representation": [
          "xmlAttr"
        ],
        "short": "Unique id for inter-element referencing",
        "definition": "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Element.id",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
                "valueUrl": "string"
              }
            ],
            "code": "http://hl7.org/fhirpath/System.String"
          }
        ],
        "isModifier": false,
        "isSummary": false,
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          }
        ]
      },
      {
        "id": "Extension.extension:attributeEstimate.extension:note.extension",
        "path": "Extension.extension.extension.extension",
        "slicing": {
          "discriminator": [
            {
              "type": "value",
              "path": "url"
            }
          ],
          "description": "Extensions are always sliced by (at least) url",
          "rules": "open"
        },
        "short": "Additional content defined by implementations",
        "definition": "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance  applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.",
        "comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
        "alias": [
          "extensions",
          "user content"
        ],
        "min": 0,
        "max": "*",
        "base": {
          "path": "Element.extension",
          "min": 0,
          "max": "*"
        },
        "type": [
          {
            "code": "Extension"
          }
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element|4.0.1"
          },
          {
            "key": "ext-1",
            "severity": "error",
            "human": "Must have either extensions or value[x], not both",
            "expression": "extension.exists() != value.exists()",
            "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
            "source": "http://hl7.org/fhir/StructureDefinition/Extension|4.0.1"
          }
        ],
        "isModifier": false,
        "isSummary": false,
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          }
        ]
      },
      {
        "id": "Extension.extension:attributeEstimate.extension:note.url",
        "path": "Extension.extension.extension.url",
        "representation": [
          "xmlAttr"
        ],
        "short": "identifies the meaning of the extension",
        "definition": "Source of the definition for the extension code - a logical name or a URL.",
        "comment": "The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.",
        "min": 1,
        "max": "1",
        "base": {
          "path": "Extension.url",
          "min": 1,
          "max": "1"
        },
        "type": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
                "valueUrl": "uri"
              }
            ],
            "code": "http://hl7.org/fhirpath/System.String"
          }
        ],
        "fixedUri": "note",
        "isModifier": false,
        "isSummary": false,
        "mapping": [
          {
            "identity": "rim",
            "map": "N/A"
          }
        ]
      },
      {
        "id": "Extension.extension:attributeEstimate.extension:note.value[x]",
        "path": "Extension.extension.extension.value[x]",
        "short": "Footnote or explanatory note about the estimate",
        "definition": "Footnote or explanatory note about the estimate.",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Extension.value[x]",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "Annotation"
          }
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element|4.0.1"
          }
        ],
        "isModifier": false,
        "isSummary": false,
        "mapping": [
          {
            "identity": "rim",
            "map": "N/A"
          }
        ]
      },
      {
        "id": "Extension.extension:attributeEstimate.extension:type",
        "path": "Extension.extension.extension",
        "sliceName": "type",
        "short": "R5: The type of attribute estimate, e.g., confidence interval or p value (new)",
        "definition": "R5: `Evidence.statistic.attributeEstimate.type` (new:CodeableConcept)",
        "comment": "Element `Evidence.statistic.attributeEstimate.type` is part of an existing definition because parent element `Evidence.statistic.attributeEstimate` requires a cross-version extension.\nElement `Evidence.statistic.attributeEstimate.type` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.attributeEstimate.type` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
        "requirements": "Element `Evidence.statistic.attributeEstimate.type` is part of an existing definition because parent element `Evidence.statistic.attributeEstimate` requires a cross-version extension.\nElement `Evidence.statistic.attributeEstimate.type` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.attributeEstimate.type` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Element.extension",
          "min": 0,
          "max": "*"
        },
        "type": [
          {
            "code": "Extension"
          }
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element|4.0.1"
          },
          {
            "key": "ext-1",
            "severity": "error",
            "human": "Must have either extensions or value[x], not both",
            "expression": "extension.exists() != value.exists()",
            "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
            "source": "http://hl7.org/fhir/StructureDefinition/Extension|4.0.1"
          }
        ],
        "isModifier": false,
        "isSummary": false
      },
      {
        "id": "Extension.extension:attributeEstimate.extension:type.id",
        "path": "Extension.extension.extension.id",
        "representation": [
          "xmlAttr"
        ],
        "short": "Unique id for inter-element referencing",
        "definition": "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Element.id",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
                "valueUrl": "string"
              }
            ],
            "code": "http://hl7.org/fhirpath/System.String"
          }
        ],
        "isModifier": false,
        "isSummary": false,
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          }
        ]
      },
      {
        "id": "Extension.extension:attributeEstimate.extension:type.extension",
        "path": "Extension.extension.extension.extension",
        "slicing": {
          "discriminator": [
            {
              "type": "value",
              "path": "url"
            }
          ],
          "description": "Extensions are always sliced by (at least) url",
          "rules": "open"
        },
        "short": "Additional content defined by implementations",
        "definition": "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance  applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.",
        "comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
        "alias": [
          "extensions",
          "user content"
        ],
        "min": 0,
        "max": "*",
        "base": {
          "path": "Element.extension",
          "min": 0,
          "max": "*"
        },
        "type": [
          {
            "code": "Extension"
          }
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element|4.0.1"
          },
          {
            "key": "ext-1",
            "severity": "error",
            "human": "Must have either extensions or value[x], not both",
            "expression": "extension.exists() != value.exists()",
            "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
            "source": "http://hl7.org/fhir/StructureDefinition/Extension|4.0.1"
          }
        ],
        "isModifier": false,
        "isSummary": false,
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          }
        ]
      },
      {
        "id": "Extension.extension:attributeEstimate.extension:type.url",
        "path": "Extension.extension.extension.url",
        "representation": [
          "xmlAttr"
        ],
        "short": "identifies the meaning of the extension",
        "definition": "Source of the definition for the extension code - a logical name or a URL.",
        "comment": "The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.",
        "min": 1,
        "max": "1",
        "base": {
          "path": "Extension.url",
          "min": 1,
          "max": "1"
        },
        "type": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
                "valueUrl": "uri"
              }
            ],
            "code": "http://hl7.org/fhirpath/System.String"
          }
        ],
        "fixedUri": "type",
        "isModifier": false,
        "isSummary": false,
        "mapping": [
          {
            "identity": "rim",
            "map": "N/A"
          }
        ]
      },
      {
        "id": "Extension.extension:attributeEstimate.extension:type.value[x]",
        "path": "Extension.extension.extension.value[x]",
        "short": "The type of attribute estimate, e.g., confidence interval or p value",
        "definition": "The type of attribute estimate, e.g., confidence interval or p value.",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Extension.value[x]",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "CodeableConcept"
          }
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element|4.0.1"
          }
        ],
        "isModifier": false,
        "isSummary": false,
        "binding": {
          "strength": "extensible",
          "valueSet": "http://hl7.org/fhir/uv/xver/ValueSet/R5-attribute-estimate-type-for-R4|0.1.0"
        },
        "mapping": [
          {
            "identity": "rim",
            "map": "N/A"
          }
        ]
      },
      {
        "id": "Extension.extension:attributeEstimate.extension:quantity",
        "path": "Extension.extension.extension",
        "sliceName": "quantity",
        "short": "R5: The singular quantity of the attribute estimate, for attribute estimates represented as single values; also used to report unit of measure (new)",
        "definition": "R5: `Evidence.statistic.attributeEstimate.quantity` (new:Quantity)",
        "comment": "Element `Evidence.statistic.attributeEstimate.quantity` is part of an existing definition because parent element `Evidence.statistic.attributeEstimate` requires a cross-version extension.\nElement `Evidence.statistic.attributeEstimate.quantity` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.attributeEstimate.quantity` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).\nOften the p value",
        "requirements": "Element `Evidence.statistic.attributeEstimate.quantity` is part of an existing definition because parent element `Evidence.statistic.attributeEstimate` requires a cross-version extension.\nElement `Evidence.statistic.attributeEstimate.quantity` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.attributeEstimate.quantity` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Element.extension",
          "min": 0,
          "max": "*"
        },
        "type": [
          {
            "code": "Extension"
          }
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element|4.0.1"
          },
          {
            "key": "ext-1",
            "severity": "error",
            "human": "Must have either extensions or value[x], not both",
            "expression": "extension.exists() != value.exists()",
            "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
            "source": "http://hl7.org/fhir/StructureDefinition/Extension|4.0.1"
          }
        ],
        "isModifier": false,
        "isSummary": false
      },
      {
        "id": "Extension.extension:attributeEstimate.extension:quantity.id",
        "path": "Extension.extension.extension.id",
        "representation": [
          "xmlAttr"
        ],
        "short": "Unique id for inter-element referencing",
        "definition": "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Element.id",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
                "valueUrl": "string"
              }
            ],
            "code": "http://hl7.org/fhirpath/System.String"
          }
        ],
        "isModifier": false,
        "isSummary": false,
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          }
        ]
      },
      {
        "id": "Extension.extension:attributeEstimate.extension:quantity.extension",
        "path": "Extension.extension.extension.extension",
        "slicing": {
          "discriminator": [
            {
              "type": "value",
              "path": "url"
            }
          ],
          "description": "Extensions are always sliced by (at least) url",
          "rules": "open"
        },
        "short": "Additional content defined by implementations",
        "definition": "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance  applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.",
        "comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
        "alias": [
          "extensions",
          "user content"
        ],
        "min": 0,
        "max": "*",
        "base": {
          "path": "Element.extension",
          "min": 0,
          "max": "*"
        },
        "type": [
          {
            "code": "Extension"
          }
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element|4.0.1"
          },
          {
            "key": "ext-1",
            "severity": "error",
            "human": "Must have either extensions or value[x], not both",
            "expression": "extension.exists() != value.exists()",
            "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
            "source": "http://hl7.org/fhir/StructureDefinition/Extension|4.0.1"
          }
        ],
        "isModifier": false,
        "isSummary": false,
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          }
        ]
      },
      {
        "id": "Extension.extension:attributeEstimate.extension:quantity.url",
        "path": "Extension.extension.extension.url",
        "representation": [
          "xmlAttr"
        ],
        "short": "identifies the meaning of the extension",
        "definition": "Source of the definition for the extension code - a logical name or a URL.",
        "comment": "The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.",
        "min": 1,
        "max": "1",
        "base": {
          "path": "Extension.url",
          "min": 1,
          "max": "1"
        },
        "type": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
                "valueUrl": "uri"
              }
            ],
            "code": "http://hl7.org/fhirpath/System.String"
          }
        ],
        "fixedUri": "quantity",
        "isModifier": false,
        "isSummary": false,
        "mapping": [
          {
            "identity": "rim",
            "map": "N/A"
          }
        ]
      },
      {
        "id": "Extension.extension:attributeEstimate.extension:quantity.value[x]",
        "path": "Extension.extension.extension.value[x]",
        "short": "The singular quantity of the attribute estimate, for attribute estimates represented as single values; also used to report unit of measure",
        "definition": "The singular quantity of the attribute estimate, for attribute estimates represented as single values; also used to report unit of measure.",
        "comment": "Often the p value",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Extension.value[x]",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "Quantity"
          }
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element|4.0.1"
          }
        ],
        "isModifier": false,
        "isSummary": false,
        "mapping": [
          {
            "identity": "rim",
            "map": "N/A"
          }
        ]
      },
      {
        "id": "Extension.extension:attributeEstimate.extension:level",
        "path": "Extension.extension.extension",
        "sliceName": "level",
        "short": "R5: Level of confidence interval, e.g., 0.95 for 95% confidence interval (new)",
        "definition": "R5: `Evidence.statistic.attributeEstimate.level` (new:decimal)",
        "comment": "Element `Evidence.statistic.attributeEstimate.level` is part of an existing definition because parent element `Evidence.statistic.attributeEstimate` requires a cross-version extension.\nElement `Evidence.statistic.attributeEstimate.level` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.attributeEstimate.level` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
        "requirements": "Element `Evidence.statistic.attributeEstimate.level` is part of an existing definition because parent element `Evidence.statistic.attributeEstimate` requires a cross-version extension.\nElement `Evidence.statistic.attributeEstimate.level` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.attributeEstimate.level` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Element.extension",
          "min": 0,
          "max": "*"
        },
        "type": [
          {
            "code": "Extension"
          }
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element|4.0.1"
          },
          {
            "key": "ext-1",
            "severity": "error",
            "human": "Must have either extensions or value[x], not both",
            "expression": "extension.exists() != value.exists()",
            "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
            "source": "http://hl7.org/fhir/StructureDefinition/Extension|4.0.1"
          }
        ],
        "isModifier": false,
        "isSummary": false
      },
      {
        "id": "Extension.extension:attributeEstimate.extension:level.id",
        "path": "Extension.extension.extension.id",
        "representation": [
          "xmlAttr"
        ],
        "short": "Unique id for inter-element referencing",
        "definition": "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Element.id",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
                "valueUrl": "string"
              }
            ],
            "code": "http://hl7.org/fhirpath/System.String"
          }
        ],
        "isModifier": false,
        "isSummary": false,
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          }
        ]
      },
      {
        "id": "Extension.extension:attributeEstimate.extension:level.extension",
        "path": "Extension.extension.extension.extension",
        "slicing": {
          "discriminator": [
            {
              "type": "value",
              "path": "url"
            }
          ],
          "description": "Extensions are always sliced by (at least) url",
          "rules": "open"
        },
        "short": "Additional content defined by implementations",
        "definition": "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance  applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.",
        "comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
        "alias": [
          "extensions",
          "user content"
        ],
        "min": 0,
        "max": "*",
        "base": {
          "path": "Element.extension",
          "min": 0,
          "max": "*"
        },
        "type": [
          {
            "code": "Extension"
          }
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element|4.0.1"
          },
          {
            "key": "ext-1",
            "severity": "error",
            "human": "Must have either extensions or value[x], not both",
            "expression": "extension.exists() != value.exists()",
            "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
            "source": "http://hl7.org/fhir/StructureDefinition/Extension|4.0.1"
          }
        ],
        "isModifier": false,
        "isSummary": false,
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          }
        ]
      },
      {
        "id": "Extension.extension:attributeEstimate.extension:level.url",
        "path": "Extension.extension.extension.url",
        "representation": [
          "xmlAttr"
        ],
        "short": "identifies the meaning of the extension",
        "definition": "Source of the definition for the extension code - a logical name or a URL.",
        "comment": "The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.",
        "min": 1,
        "max": "1",
        "base": {
          "path": "Extension.url",
          "min": 1,
          "max": "1"
        },
        "type": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
                "valueUrl": "uri"
              }
            ],
            "code": "http://hl7.org/fhirpath/System.String"
          }
        ],
        "fixedUri": "level",
        "isModifier": false,
        "isSummary": false,
        "mapping": [
          {
            "identity": "rim",
            "map": "N/A"
          }
        ]
      },
      {
        "id": "Extension.extension:attributeEstimate.extension:level.value[x]",
        "path": "Extension.extension.extension.value[x]",
        "short": "Level of confidence interval, e.g., 0.95 for 95% confidence interval",
        "definition": "Use 95 for a 95% confidence interval.",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Extension.value[x]",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "decimal"
          }
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element|4.0.1"
          }
        ],
        "isModifier": false,
        "isSummary": false,
        "mapping": [
          {
            "identity": "rim",
            "map": "N/A"
          }
        ]
      },
      {
        "id": "Extension.extension:attributeEstimate.extension:range",
        "path": "Extension.extension.extension",
        "sliceName": "range",
        "short": "R5: Lower and upper bound values of the attribute estimate (new)",
        "definition": "R5: `Evidence.statistic.attributeEstimate.range` (new:Range)",
        "comment": "Element `Evidence.statistic.attributeEstimate.range` is part of an existing definition because parent element `Evidence.statistic.attributeEstimate` requires a cross-version extension.\nElement `Evidence.statistic.attributeEstimate.range` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.attributeEstimate.range` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
        "requirements": "Element `Evidence.statistic.attributeEstimate.range` is part of an existing definition because parent element `Evidence.statistic.attributeEstimate` requires a cross-version extension.\nElement `Evidence.statistic.attributeEstimate.range` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.attributeEstimate.range` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Element.extension",
          "min": 0,
          "max": "*"
        },
        "type": [
          {
            "code": "Extension"
          }
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element|4.0.1"
          },
          {
            "key": "ext-1",
            "severity": "error",
            "human": "Must have either extensions or value[x], not both",
            "expression": "extension.exists() != value.exists()",
            "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
            "source": "http://hl7.org/fhir/StructureDefinition/Extension|4.0.1"
          }
        ],
        "isModifier": false,
        "isSummary": false
      },
      {
        "id": "Extension.extension:attributeEstimate.extension:range.id",
        "path": "Extension.extension.extension.id",
        "representation": [
          "xmlAttr"
        ],
        "short": "Unique id for inter-element referencing",
        "definition": "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Element.id",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
                "valueUrl": "string"
              }
            ],
            "code": "http://hl7.org/fhirpath/System.String"
          }
        ],
        "isModifier": false,
        "isSummary": false,
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          }
        ]
      },
      {
        "id": "Extension.extension:attributeEstimate.extension:range.extension",
        "path": "Extension.extension.extension.extension",
        "slicing": {
          "discriminator": [
            {
              "type": "value",
              "path": "url"
            }
          ],
          "description": "Extensions are always sliced by (at least) url",
          "rules": "open"
        },
        "short": "Additional content defined by implementations",
        "definition": "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance  applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.",
        "comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
        "alias": [
          "extensions",
          "user content"
        ],
        "min": 0,
        "max": "*",
        "base": {
          "path": "Element.extension",
          "min": 0,
          "max": "*"
        },
        "type": [
          {
            "code": "Extension"
          }
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element|4.0.1"
          },
          {
            "key": "ext-1",
            "severity": "error",
            "human": "Must have either extensions or value[x], not both",
            "expression": "extension.exists() != value.exists()",
            "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
            "source": "http://hl7.org/fhir/StructureDefinition/Extension|4.0.1"
          }
        ],
        "isModifier": false,
        "isSummary": false,
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          }
        ]
      },
      {
        "id": "Extension.extension:attributeEstimate.extension:range.url",
        "path": "Extension.extension.extension.url",
        "representation": [
          "xmlAttr"
        ],
        "short": "identifies the meaning of the extension",
        "definition": "Source of the definition for the extension code - a logical name or a URL.",
        "comment": "The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.",
        "min": 1,
        "max": "1",
        "base": {
          "path": "Extension.url",
          "min": 1,
          "max": "1"
        },
        "type": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
                "valueUrl": "uri"
              }
            ],
            "code": "http://hl7.org/fhirpath/System.String"
          }
        ],
        "fixedUri": "range",
        "isModifier": false,
        "isSummary": false,
        "mapping": [
          {
            "identity": "rim",
            "map": "N/A"
          }
        ]
      },
      {
        "id": "Extension.extension:attributeEstimate.extension:range.value[x]",
        "path": "Extension.extension.extension.value[x]",
        "short": "Lower and upper bound values of the attribute estimate",
        "definition": "Lower bound of confidence interval.",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Extension.value[x]",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "Range"
          }
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element|4.0.1"
          }
        ],
        "isModifier": false,
        "isSummary": false,
        "mapping": [
          {
            "identity": "rim",
            "map": "N/A"
          }
        ]
      },
      {
        "id": "Extension.extension:attributeEstimate.extension:attributeEstimate",
        "path": "Extension.extension.extension",
        "sliceName": "attributeEstimate",
        "short": "R5: A nested attribute estimate; which is the attribute estimate of an attribute estimate (new)",
        "definition": "R5: `Evidence.statistic.attributeEstimate.attributeEstimate` (new:Evidence.statistic.attributeEstimate)",
        "comment": "Element `Evidence.statistic.attributeEstimate.attributeEstimate` is part of an existing definition because parent element `Evidence.statistic.attributeEstimate` requires a cross-version extension.\nElement `Evidence.statistic.attributeEstimate.attributeEstimate` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.attributeEstimate.attributeEstimate` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).\nA nested attribute estimate; which is the attribute estimate of an attribute estimate",
        "requirements": "Element `Evidence.statistic.attributeEstimate.attributeEstimate` is part of an existing definition because parent element `Evidence.statistic.attributeEstimate` requires a cross-version extension.\nElement `Evidence.statistic.attributeEstimate.attributeEstimate` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.attributeEstimate.attributeEstimate` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
        "min": 0,
        "max": "*",
        "base": {
          "path": "Element.extension",
          "min": 0,
          "max": "*"
        },
        "type": [
          {
            "code": "Extension"
          }
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element|4.0.1"
          },
          {
            "key": "ext-1",
            "severity": "error",
            "human": "Must have either extensions or value[x], not both",
            "expression": "extension.exists() != value.exists()",
            "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
            "source": "http://hl7.org/fhir/StructureDefinition/Extension|4.0.1"
          }
        ],
        "isModifier": false,
        "isSummary": false
      },
      {
        "id": "Extension.extension:attributeEstimate.extension:attributeEstimate.id",
        "path": "Extension.extension.extension.id",
        "representation": [
          "xmlAttr"
        ],
        "short": "Unique id for inter-element referencing",
        "definition": "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Element.id",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
                "valueUrl": "string"
              }
            ],
            "code": "http://hl7.org/fhirpath/System.String"
          }
        ],
        "isModifier": false,
        "isSummary": false,
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          }
        ]
      },
      {
        "id": "Extension.extension:attributeEstimate.extension:attributeEstimate.extension",
        "path": "Extension.extension.extension.extension",
        "slicing": {
          "discriminator": [
            {
              "type": "value",
              "path": "url"
            }
          ],
          "description": "Extensions are always sliced by (at least) url",
          "rules": "open"
        },
        "short": "Additional content defined by implementations",
        "definition": "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance  applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.",
        "comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
        "alias": [
          "extensions",
          "user content"
        ],
        "min": 0,
        "max": "*",
        "base": {
          "path": "Element.extension",
          "min": 0,
          "max": "*"
        },
        "type": [
          {
            "code": "Extension"
          }
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element|4.0.1"
          },
          {
            "key": "ext-1",
            "severity": "error",
            "human": "Must have either extensions or value[x], not both",
            "expression": "extension.exists() != value.exists()",
            "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
            "source": "http://hl7.org/fhir/StructureDefinition/Extension|4.0.1"
          }
        ],
        "isModifier": false,
        "isSummary": false,
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          }
        ]
      },
      {
        "id": "Extension.extension:attributeEstimate.extension:attributeEstimate.url",
        "path": "Extension.extension.extension.url",
        "representation": [
          "xmlAttr"
        ],
        "short": "identifies the meaning of the extension",
        "definition": "Source of the definition for the extension code - a logical name or a URL.",
        "comment": "The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.",
        "min": 1,
        "max": "1",
        "base": {
          "path": "Extension.url",
          "min": 1,
          "max": "1"
        },
        "type": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
                "valueUrl": "uri"
              }
            ],
            "code": "http://hl7.org/fhirpath/System.String"
          }
        ],
        "fixedUri": "http://hl7.org/fhir/5.0/StructureDefinition/extension-Evidence.statistic.attributeEstimate",
        "isModifier": false,
        "isSummary": false,
        "mapping": [
          {
            "identity": "rim",
            "map": "N/A"
          }
        ]
      },
      {
        "id": "Extension.extension:attributeEstimate.extension:attributeEstimate.value[x]",
        "path": "Extension.extension.extension.value[x]",
        "short": "Value of extension",
        "definition": "Value of extension - must be one of a constrained set of the data types (see [Extensibility](http://hl7.org/fhir/R4/extensibility.html) for a list).",
        "min": 0,
        "max": "0",
        "base": {
          "path": "Extension.value[x]",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "base64Binary"
          },
          {
            "code": "boolean"
          },
          {
            "code": "canonical"
          },
          {
            "code": "code"
          },
          {
            "code": "date"
          },
          {
            "code": "dateTime"
          },
          {
            "code": "decimal"
          },
          {
            "code": "id"
          },
          {
            "code": "instant"
          },
          {
            "code": "integer"
          },
          {
            "code": "markdown"
          },
          {
            "code": "oid"
          },
          {
            "code": "positiveInt"
          },
          {
            "code": "string"
          },
          {
            "code": "time"
          },
          {
            "code": "unsignedInt"
          },
          {
            "code": "uri"
          },
          {
            "code": "url"
          },
          {
            "code": "uuid"
          },
          {
            "code": "Address"
          },
          {
            "code": "Age"
          },
          {
            "code": "Annotation"
          },
          {
            "code": "Attachment"
          },
          {
            "code": "CodeableConcept"
          },
          {
            "code": "Coding"
          },
          {
            "code": "ContactPoint"
          },
          {
            "code": "Count"
          },
          {
            "code": "Distance"
          },
          {
            "code": "Duration"
          },
          {
            "code": "HumanName"
          },
          {
            "code": "Identifier"
          },
          {
            "code": "Money"
          },
          {
            "code": "Period"
          },
          {
            "code": "Quantity"
          },
          {
            "code": "Range"
          },
          {
            "code": "Ratio"
          },
          {
            "code": "Reference"
          },
          {
            "code": "SampledData"
          },
          {
            "code": "Signature"
          },
          {
            "code": "Timing"
          },
          {
            "code": "ContactDetail"
          },
          {
            "code": "Contributor"
          },
          {
            "code": "DataRequirement"
          },
          {
            "code": "Expression"
          },
          {
            "code": "ParameterDefinition"
          },
          {
            "code": "RelatedArtifact"
          },
          {
            "code": "TriggerDefinition"
          },
          {
            "code": "UsageContext"
          },
          {
            "code": "Dosage"
          },
          {
            "code": "Meta"
          }
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element|4.0.1"
          }
        ],
        "isModifier": false,
        "isSummary": false,
        "mapping": [
          {
            "identity": "rim",
            "map": "N/A"
          }
        ]
      },
      {
        "id": "Extension.extension:attributeEstimate.url",
        "path": "Extension.extension.url",
        "representation": [
          "xmlAttr"
        ],
        "short": "identifies the meaning of the extension",
        "definition": "Source of the definition for the extension code - a logical name or a URL.",
        "comment": "The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.",
        "min": 1,
        "max": "1",
        "base": {
          "path": "Extension.url",
          "min": 1,
          "max": "1"
        },
        "type": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
                "valueUrl": "uri"
              }
            ],
            "code": "http://hl7.org/fhirpath/System.String"
          }
        ],
        "fixedUri": "attributeEstimate",
        "isModifier": false,
        "isSummary": false,
        "mapping": [
          {
            "identity": "rim",
            "map": "N/A"
          }
        ]
      },
      {
        "id": "Extension.extension:attributeEstimate.value[x]",
        "path": "Extension.extension.value[x]",
        "short": "Value of extension",
        "definition": "Value of extension - must be one of a constrained set of the data types (see [Extensibility](http://hl7.org/fhir/R4/extensibility.html) for a list).",
        "min": 0,
        "max": "0",
        "base": {
          "path": "Extension.value[x]",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "base64Binary"
          },
          {
            "code": "boolean"
          },
          {
            "code": "canonical"
          },
          {
            "code": "code"
          },
          {
            "code": "date"
          },
          {
            "code": "dateTime"
          },
          {
            "code": "decimal"
          },
          {
            "code": "id"
          },
          {
            "code": "instant"
          },
          {
            "code": "integer"
          },
          {
            "code": "markdown"
          },
          {
            "code": "oid"
          },
          {
            "code": "positiveInt"
          },
          {
            "code": "string"
          },
          {
            "code": "time"
          },
          {
            "code": "unsignedInt"
          },
          {
            "code": "uri"
          },
          {
            "code": "url"
          },
          {
            "code": "uuid"
          },
          {
            "code": "Address"
          },
          {
            "code": "Age"
          },
          {
            "code": "Annotation"
          },
          {
            "code": "Attachment"
          },
          {
            "code": "CodeableConcept"
          },
          {
            "code": "Coding"
          },
          {
            "code": "ContactPoint"
          },
          {
            "code": "Count"
          },
          {
            "code": "Distance"
          },
          {
            "code": "Duration"
          },
          {
            "code": "HumanName"
          },
          {
            "code": "Identifier"
          },
          {
            "code": "Money"
          },
          {
            "code": "Period"
          },
          {
            "code": "Quantity"
          },
          {
            "code": "Range"
          },
          {
            "code": "Ratio"
          },
          {
            "code": "Reference"
          },
          {
            "code": "SampledData"
          },
          {
            "code": "Signature"
          },
          {
            "code": "Timing"
          },
          {
            "code": "ContactDetail"
          },
          {
            "code": "Contributor"
          },
          {
            "code": "DataRequirement"
          },
          {
            "code": "Expression"
          },
          {
            "code": "ParameterDefinition"
          },
          {
            "code": "RelatedArtifact"
          },
          {
            "code": "TriggerDefinition"
          },
          {
            "code": "UsageContext"
          },
          {
            "code": "Dosage"
          },
          {
            "code": "Meta"
          }
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element|4.0.1"
          }
        ],
        "isModifier": false,
        "isSummary": false,
        "mapping": [
          {
            "identity": "rim",
            "map": "N/A"
          }
        ]
      },
      {
        "id": "Extension.extension:modelCharacteristic",
        "path": "Extension.extension",
        "sliceName": "modelCharacteristic",
        "short": "R5: An aspect of the statistical model (new)",
        "definition": "R5: `Evidence.statistic.modelCharacteristic` (new:BackboneElement)",
        "comment": "Element `Evidence.statistic.modelCharacteristic` is part of an existing definition because parent element `Evidence.statistic` requires a cross-version extension.\nElement `Evidence.statistic.modelCharacteristic` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.modelCharacteristic` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
        "requirements": "Element `Evidence.statistic.modelCharacteristic` is part of an existing definition because parent element `Evidence.statistic` requires a cross-version extension.\nElement `Evidence.statistic.modelCharacteristic` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.modelCharacteristic` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
        "min": 0,
        "max": "*",
        "base": {
          "path": "Element.extension",
          "min": 0,
          "max": "*"
        },
        "type": [
          {
            "code": "Extension"
          }
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element|4.0.1"
          },
          {
            "key": "ext-1",
            "severity": "error",
            "human": "Must have either extensions or value[x], not both",
            "expression": "extension.exists() != value.exists()",
            "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
            "source": "http://hl7.org/fhir/StructureDefinition/Extension|4.0.1"
          }
        ],
        "isModifier": false,
        "isSummary": false
      },
      {
        "id": "Extension.extension:modelCharacteristic.id",
        "path": "Extension.extension.id",
        "representation": [
          "xmlAttr"
        ],
        "short": "Unique id for inter-element referencing",
        "definition": "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Element.id",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
                "valueUrl": "string"
              }
            ],
            "code": "http://hl7.org/fhirpath/System.String"
          }
        ],
        "isModifier": false,
        "isSummary": false,
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          }
        ]
      },
      {
        "id": "Extension.extension:modelCharacteristic.extension",
        "path": "Extension.extension.extension",
        "slicing": {
          "discriminator": [
            {
              "type": "value",
              "path": "url"
            }
          ],
          "description": "Extensions are always sliced by (at least) url",
          "ordered": false,
          "rules": "open"
        },
        "short": "Extension",
        "definition": "An Extension",
        "min": 1,
        "max": "*",
        "base": {
          "path": "Element.extension",
          "min": 0,
          "max": "*"
        },
        "type": [
          {
            "code": "Extension"
          }
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element|4.0.1"
          },
          {
            "key": "ext-1",
            "severity": "error",
            "human": "Must have either extensions or value[x], not both",
            "expression": "extension.exists() != value.exists()",
            "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
            "source": "http://hl7.org/fhir/StructureDefinition/Extension|4.0.1"
          }
        ],
        "isModifier": false,
        "isSummary": false
      },
      {
        "id": "Extension.extension:modelCharacteristic.extension:code",
        "path": "Extension.extension.extension",
        "sliceName": "code",
        "short": "R5: Model specification (new)",
        "definition": "R5: `Evidence.statistic.modelCharacteristic.code` (new:CodeableConcept)",
        "comment": "Element `Evidence.statistic.modelCharacteristic.code` is part of an existing definition because parent element `Evidence.statistic.modelCharacteristic` requires a cross-version extension.\nElement `Evidence.statistic.modelCharacteristic.code` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.modelCharacteristic.code` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
        "requirements": "Element `Evidence.statistic.modelCharacteristic.code` is part of an existing definition because parent element `Evidence.statistic.modelCharacteristic` requires a cross-version extension.\nElement `Evidence.statistic.modelCharacteristic.code` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.modelCharacteristic.code` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
        "min": 1,
        "max": "1",
        "base": {
          "path": "Element.extension",
          "min": 0,
          "max": "*"
        },
        "type": [
          {
            "code": "Extension"
          }
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element|4.0.1"
          },
          {
            "key": "ext-1",
            "severity": "error",
            "human": "Must have either extensions or value[x], not both",
            "expression": "extension.exists() != value.exists()",
            "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
            "source": "http://hl7.org/fhir/StructureDefinition/Extension|4.0.1"
          }
        ],
        "isModifier": false,
        "isSummary": false
      },
      {
        "id": "Extension.extension:modelCharacteristic.extension:code.id",
        "path": "Extension.extension.extension.id",
        "representation": [
          "xmlAttr"
        ],
        "short": "Unique id for inter-element referencing",
        "definition": "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Element.id",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
                "valueUrl": "string"
              }
            ],
            "code": "http://hl7.org/fhirpath/System.String"
          }
        ],
        "isModifier": false,
        "isSummary": false,
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          }
        ]
      },
      {
        "id": "Extension.extension:modelCharacteristic.extension:code.extension",
        "path": "Extension.extension.extension.extension",
        "slicing": {
          "discriminator": [
            {
              "type": "value",
              "path": "url"
            }
          ],
          "description": "Extensions are always sliced by (at least) url",
          "rules": "open"
        },
        "short": "Additional content defined by implementations",
        "definition": "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance  applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.",
        "comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
        "alias": [
          "extensions",
          "user content"
        ],
        "min": 0,
        "max": "*",
        "base": {
          "path": "Element.extension",
          "min": 0,
          "max": "*"
        },
        "type": [
          {
            "code": "Extension"
          }
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element|4.0.1"
          },
          {
            "key": "ext-1",
            "severity": "error",
            "human": "Must have either extensions or value[x], not both",
            "expression": "extension.exists() != value.exists()",
            "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
            "source": "http://hl7.org/fhir/StructureDefinition/Extension|4.0.1"
          }
        ],
        "isModifier": false,
        "isSummary": false,
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          }
        ]
      },
      {
        "id": "Extension.extension:modelCharacteristic.extension:code.url",
        "path": "Extension.extension.extension.url",
        "representation": [
          "xmlAttr"
        ],
        "short": "identifies the meaning of the extension",
        "definition": "Source of the definition for the extension code - a logical name or a URL.",
        "comment": "The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.",
        "min": 1,
        "max": "1",
        "base": {
          "path": "Extension.url",
          "min": 1,
          "max": "1"
        },
        "type": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
                "valueUrl": "uri"
              }
            ],
            "code": "http://hl7.org/fhirpath/System.String"
          }
        ],
        "fixedUri": "code",
        "isModifier": false,
        "isSummary": false,
        "mapping": [
          {
            "identity": "rim",
            "map": "N/A"
          }
        ]
      },
      {
        "id": "Extension.extension:modelCharacteristic.extension:code.value[x]",
        "path": "Extension.extension.extension.value[x]",
        "short": "Model specification",
        "definition": "Description of a component of the method to generate the statistic.",
        "min": 1,
        "max": "1",
        "base": {
          "path": "Extension.value[x]",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "CodeableConcept"
          }
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element|4.0.1"
          }
        ],
        "isModifier": false,
        "isSummary": false,
        "binding": {
          "strength": "extensible",
          "valueSet": "http://hl7.org/fhir/uv/xver/ValueSet/R5-statistic-model-code-for-R4|0.1.0"
        },
        "mapping": [
          {
            "identity": "rim",
            "map": "N/A"
          }
        ]
      },
      {
        "id": "Extension.extension:modelCharacteristic.extension:value",
        "path": "Extension.extension.extension",
        "sliceName": "value",
        "short": "R5: Numerical value to complete model specification (new)",
        "definition": "R5: `Evidence.statistic.modelCharacteristic.value` (new:Quantity[SimpleQuantity])",
        "comment": "Element `Evidence.statistic.modelCharacteristic.value` is part of an existing definition because parent element `Evidence.statistic.modelCharacteristic` requires a cross-version extension.\nElement `Evidence.statistic.modelCharacteristic.value` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.modelCharacteristic.value` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
        "requirements": "Element `Evidence.statistic.modelCharacteristic.value` is part of an existing definition because parent element `Evidence.statistic.modelCharacteristic` requires a cross-version extension.\nElement `Evidence.statistic.modelCharacteristic.value` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.modelCharacteristic.value` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Element.extension",
          "min": 0,
          "max": "*"
        },
        "type": [
          {
            "code": "Extension"
          }
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element|4.0.1"
          },
          {
            "key": "ext-1",
            "severity": "error",
            "human": "Must have either extensions or value[x], not both",
            "expression": "extension.exists() != value.exists()",
            "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
            "source": "http://hl7.org/fhir/StructureDefinition/Extension|4.0.1"
          }
        ],
        "isModifier": false,
        "isSummary": false
      },
      {
        "id": "Extension.extension:modelCharacteristic.extension:value.id",
        "path": "Extension.extension.extension.id",
        "representation": [
          "xmlAttr"
        ],
        "short": "Unique id for inter-element referencing",
        "definition": "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Element.id",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
                "valueUrl": "string"
              }
            ],
            "code": "http://hl7.org/fhirpath/System.String"
          }
        ],
        "isModifier": false,
        "isSummary": false,
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          }
        ]
      },
      {
        "id": "Extension.extension:modelCharacteristic.extension:value.extension",
        "path": "Extension.extension.extension.extension",
        "slicing": {
          "discriminator": [
            {
              "type": "value",
              "path": "url"
            }
          ],
          "description": "Extensions are always sliced by (at least) url",
          "rules": "open"
        },
        "short": "Additional content defined by implementations",
        "definition": "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance  applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.",
        "comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
        "alias": [
          "extensions",
          "user content"
        ],
        "min": 0,
        "max": "*",
        "base": {
          "path": "Element.extension",
          "min": 0,
          "max": "*"
        },
        "type": [
          {
            "code": "Extension"
          }
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element|4.0.1"
          },
          {
            "key": "ext-1",
            "severity": "error",
            "human": "Must have either extensions or value[x], not both",
            "expression": "extension.exists() != value.exists()",
            "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
            "source": "http://hl7.org/fhir/StructureDefinition/Extension|4.0.1"
          }
        ],
        "isModifier": false,
        "isSummary": false,
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          }
        ]
      },
      {
        "id": "Extension.extension:modelCharacteristic.extension:value.url",
        "path": "Extension.extension.extension.url",
        "representation": [
          "xmlAttr"
        ],
        "short": "identifies the meaning of the extension",
        "definition": "Source of the definition for the extension code - a logical name or a URL.",
        "comment": "The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.",
        "min": 1,
        "max": "1",
        "base": {
          "path": "Extension.url",
          "min": 1,
          "max": "1"
        },
        "type": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
                "valueUrl": "uri"
              }
            ],
            "code": "http://hl7.org/fhirpath/System.String"
          }
        ],
        "fixedUri": "value",
        "isModifier": false,
        "isSummary": false,
        "mapping": [
          {
            "identity": "rim",
            "map": "N/A"
          }
        ]
      },
      {
        "id": "Extension.extension:modelCharacteristic.extension:value.value[x]",
        "path": "Extension.extension.extension.value[x]",
        "short": "Numerical value to complete model specification",
        "definition": "Further specification of the quantified value of the component of the method to generate the statistic.",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Extension.value[x]",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "Quantity",
            "profile": [
              "http://hl7.org/fhir/StructureDefinition/SimpleQuantity|4.0.1"
            ]
          }
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element|4.0.1"
          }
        ],
        "isModifier": false,
        "isSummary": false,
        "mapping": [
          {
            "identity": "rim",
            "map": "N/A"
          }
        ]
      },
      {
        "id": "Extension.extension:modelCharacteristic.extension:variable",
        "path": "Extension.extension.extension",
        "sliceName": "variable",
        "short": "R5: A variable adjusted for in the adjusted analysis (new)",
        "definition": "R5: `Evidence.statistic.modelCharacteristic.variable` (new:BackboneElement)",
        "comment": "Element `Evidence.statistic.modelCharacteristic.variable` is part of an existing definition because parent element `Evidence.statistic.modelCharacteristic` requires a cross-version extension.\nElement `Evidence.statistic.modelCharacteristic.variable` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.modelCharacteristic.variable` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
        "requirements": "Element `Evidence.statistic.modelCharacteristic.variable` is part of an existing definition because parent element `Evidence.statistic.modelCharacteristic` requires a cross-version extension.\nElement `Evidence.statistic.modelCharacteristic.variable` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.modelCharacteristic.variable` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
        "min": 0,
        "max": "*",
        "base": {
          "path": "Element.extension",
          "min": 0,
          "max": "*"
        },
        "type": [
          {
            "code": "Extension"
          }
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element|4.0.1"
          },
          {
            "key": "ext-1",
            "severity": "error",
            "human": "Must have either extensions or value[x], not both",
            "expression": "extension.exists() != value.exists()",
            "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
            "source": "http://hl7.org/fhir/StructureDefinition/Extension|4.0.1"
          }
        ],
        "isModifier": false,
        "isSummary": false
      },
      {
        "id": "Extension.extension:modelCharacteristic.extension:variable.id",
        "path": "Extension.extension.extension.id",
        "representation": [
          "xmlAttr"
        ],
        "short": "Unique id for inter-element referencing",
        "definition": "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Element.id",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
                "valueUrl": "string"
              }
            ],
            "code": "http://hl7.org/fhirpath/System.String"
          }
        ],
        "isModifier": false,
        "isSummary": false,
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          }
        ]
      },
      {
        "id": "Extension.extension:modelCharacteristic.extension:variable.extension",
        "path": "Extension.extension.extension.extension",
        "slicing": {
          "discriminator": [
            {
              "type": "value",
              "path": "url"
            }
          ],
          "description": "Extensions are always sliced by (at least) url",
          "ordered": false,
          "rules": "open"
        },
        "short": "Extension",
        "definition": "An Extension",
        "min": 1,
        "max": "*",
        "base": {
          "path": "Element.extension",
          "min": 0,
          "max": "*"
        },
        "type": [
          {
            "code": "Extension"
          }
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element|4.0.1"
          },
          {
            "key": "ext-1",
            "severity": "error",
            "human": "Must have either extensions or value[x], not both",
            "expression": "extension.exists() != value.exists()",
            "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
            "source": "http://hl7.org/fhir/StructureDefinition/Extension|4.0.1"
          }
        ],
        "isModifier": false,
        "isSummary": false
      },
      {
        "id": "Extension.extension:modelCharacteristic.extension:variable.extension:variableDefinition",
        "path": "Extension.extension.extension.extension",
        "sliceName": "variableDefinition",
        "short": "R5: Description of the variable (new)",
        "definition": "R5: `Evidence.statistic.modelCharacteristic.variable.variableDefinition` (new:Reference(Group,EvidenceVariable))",
        "comment": "Element `Evidence.statistic.modelCharacteristic.variable.variableDefinition` is part of an existing definition because parent element `Evidence.statistic.modelCharacteristic.variable` requires a cross-version extension.\nElement `Evidence.statistic.modelCharacteristic.variable.variableDefinition` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.modelCharacteristic.variable.variableDefinition` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
        "requirements": "Element `Evidence.statistic.modelCharacteristic.variable.variableDefinition` is part of an existing definition because parent element `Evidence.statistic.modelCharacteristic.variable` requires a cross-version extension.\nElement `Evidence.statistic.modelCharacteristic.variable.variableDefinition` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.modelCharacteristic.variable.variableDefinition` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
        "min": 1,
        "max": "1",
        "base": {
          "path": "Element.extension",
          "min": 0,
          "max": "*"
        },
        "type": [
          {
            "code": "Extension"
          }
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element|4.0.1"
          },
          {
            "key": "ext-1",
            "severity": "error",
            "human": "Must have either extensions or value[x], not both",
            "expression": "extension.exists() != value.exists()",
            "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
            "source": "http://hl7.org/fhir/StructureDefinition/Extension|4.0.1"
          }
        ],
        "isModifier": false,
        "isSummary": false
      },
      {
        "id": "Extension.extension:modelCharacteristic.extension:variable.extension:variableDefinition.id",
        "path": "Extension.extension.extension.extension.id",
        "representation": [
          "xmlAttr"
        ],
        "short": "Unique id for inter-element referencing",
        "definition": "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Element.id",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
                "valueUrl": "string"
              }
            ],
            "code": "http://hl7.org/fhirpath/System.String"
          }
        ],
        "isModifier": false,
        "isSummary": false,
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          }
        ]
      },
      {
        "id": "Extension.extension:modelCharacteristic.extension:variable.extension:variableDefinition.extension",
        "path": "Extension.extension.extension.extension.extension",
        "slicing": {
          "discriminator": [
            {
              "type": "value",
              "path": "url"
            }
          ],
          "description": "Extensions are always sliced by (at least) url",
          "rules": "open"
        },
        "short": "Additional content defined by implementations",
        "definition": "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance  applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.",
        "comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
        "alias": [
          "extensions",
          "user content"
        ],
        "min": 0,
        "max": "*",
        "base": {
          "path": "Element.extension",
          "min": 0,
          "max": "*"
        },
        "type": [
          {
            "code": "Extension"
          }
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element|4.0.1"
          },
          {
            "key": "ext-1",
            "severity": "error",
            "human": "Must have either extensions or value[x], not both",
            "expression": "extension.exists() != value.exists()",
            "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
            "source": "http://hl7.org/fhir/StructureDefinition/Extension|4.0.1"
          }
        ],
        "isModifier": false,
        "isSummary": false,
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          }
        ]
      },
      {
        "id": "Extension.extension:modelCharacteristic.extension:variable.extension:variableDefinition.url",
        "path": "Extension.extension.extension.extension.url",
        "representation": [
          "xmlAttr"
        ],
        "short": "identifies the meaning of the extension",
        "definition": "Source of the definition for the extension code - a logical name or a URL.",
        "comment": "The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.",
        "min": 1,
        "max": "1",
        "base": {
          "path": "Extension.url",
          "min": 1,
          "max": "1"
        },
        "type": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
                "valueUrl": "uri"
              }
            ],
            "code": "http://hl7.org/fhirpath/System.String"
          }
        ],
        "fixedUri": "variableDefinition",
        "isModifier": false,
        "isSummary": false,
        "mapping": [
          {
            "identity": "rim",
            "map": "N/A"
          }
        ]
      },
      {
        "id": "Extension.extension:modelCharacteristic.extension:variable.extension:variableDefinition.value[x]",
        "path": "Extension.extension.extension.extension.value[x]",
        "short": "Description of the variable",
        "definition": "Description of the variable.",
        "min": 1,
        "max": "1",
        "base": {
          "path": "Extension.value[x]",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "Reference",
            "targetProfile": [
              "http://hl7.org/fhir/5.0/StructureDefinition/profile-Group|0.1.0",
              "http://hl7.org/fhir/StructureDefinition/Group|4.0.1",
              "http://hl7.org/fhir/5.0/StructureDefinition/profile-EvidenceVariable|0.1.0",
              "http://hl7.org/fhir/StructureDefinition/EvidenceVariable|4.0.1"
            ]
          }
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element|4.0.1"
          }
        ],
        "isModifier": false,
        "isSummary": false,
        "mapping": [
          {
            "identity": "rim",
            "map": "N/A"
          }
        ]
      },
      {
        "id": "Extension.extension:modelCharacteristic.extension:variable.extension:handling",
        "path": "Extension.extension.extension.extension",
        "sliceName": "handling",
        "short": "R5: continuous | dichotomous | ordinal | polychotomous (new)",
        "definition": "R5: `Evidence.statistic.modelCharacteristic.variable.handling` (new:code)",
        "comment": "Element `Evidence.statistic.modelCharacteristic.variable.handling` is part of an existing definition because parent element `Evidence.statistic.modelCharacteristic.variable` requires a cross-version extension.\nElement `Evidence.statistic.modelCharacteristic.variable.handling` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.modelCharacteristic.variable.handling` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
        "requirements": "Element `Evidence.statistic.modelCharacteristic.variable.handling` is part of an existing definition because parent element `Evidence.statistic.modelCharacteristic.variable` requires a cross-version extension.\nElement `Evidence.statistic.modelCharacteristic.variable.handling` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.modelCharacteristic.variable.handling` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Element.extension",
          "min": 0,
          "max": "*"
        },
        "type": [
          {
            "code": "Extension"
          }
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element|4.0.1"
          },
          {
            "key": "ext-1",
            "severity": "error",
            "human": "Must have either extensions or value[x], not both",
            "expression": "extension.exists() != value.exists()",
            "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
            "source": "http://hl7.org/fhir/StructureDefinition/Extension|4.0.1"
          }
        ],
        "isModifier": false,
        "isSummary": false
      },
      {
        "id": "Extension.extension:modelCharacteristic.extension:variable.extension:handling.id",
        "path": "Extension.extension.extension.extension.id",
        "representation": [
          "xmlAttr"
        ],
        "short": "Unique id for inter-element referencing",
        "definition": "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Element.id",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
                "valueUrl": "string"
              }
            ],
            "code": "http://hl7.org/fhirpath/System.String"
          }
        ],
        "isModifier": false,
        "isSummary": false,
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          }
        ]
      },
      {
        "id": "Extension.extension:modelCharacteristic.extension:variable.extension:handling.extension",
        "path": "Extension.extension.extension.extension.extension",
        "slicing": {
          "discriminator": [
            {
              "type": "value",
              "path": "url"
            }
          ],
          "description": "Extensions are always sliced by (at least) url",
          "rules": "open"
        },
        "short": "Additional content defined by implementations",
        "definition": "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance  applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.",
        "comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
        "alias": [
          "extensions",
          "user content"
        ],
        "min": 0,
        "max": "*",
        "base": {
          "path": "Element.extension",
          "min": 0,
          "max": "*"
        },
        "type": [
          {
            "code": "Extension"
          }
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element|4.0.1"
          },
          {
            "key": "ext-1",
            "severity": "error",
            "human": "Must have either extensions or value[x], not both",
            "expression": "extension.exists() != value.exists()",
            "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
            "source": "http://hl7.org/fhir/StructureDefinition/Extension|4.0.1"
          }
        ],
        "isModifier": false,
        "isSummary": false,
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          }
        ]
      },
      {
        "id": "Extension.extension:modelCharacteristic.extension:variable.extension:handling.url",
        "path": "Extension.extension.extension.extension.url",
        "representation": [
          "xmlAttr"
        ],
        "short": "identifies the meaning of the extension",
        "definition": "Source of the definition for the extension code - a logical name or a URL.",
        "comment": "The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.",
        "min": 1,
        "max": "1",
        "base": {
          "path": "Extension.url",
          "min": 1,
          "max": "1"
        },
        "type": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
                "valueUrl": "uri"
              }
            ],
            "code": "http://hl7.org/fhirpath/System.String"
          }
        ],
        "fixedUri": "handling",
        "isModifier": false,
        "isSummary": false,
        "mapping": [
          {
            "identity": "rim",
            "map": "N/A"
          }
        ]
      },
      {
        "id": "Extension.extension:modelCharacteristic.extension:variable.extension:handling.value[x]",
        "path": "Extension.extension.extension.extension.value[x]",
        "short": "continuous | dichotomous | ordinal | polychotomous",
        "definition": "How the variable is classified for use in adjusted analysis.",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Extension.value[x]",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "code"
          }
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element|4.0.1"
          }
        ],
        "isModifier": false,
        "isSummary": false,
        "binding": {
          "strength": "required",
          "valueSet": "http://hl7.org/fhir/uv/xver/ValueSet/R5-variable-handling-for-R4|0.1.0"
        },
        "mapping": [
          {
            "identity": "rim",
            "map": "N/A"
          }
        ]
      },
      {
        "id": "Extension.extension:modelCharacteristic.extension:variable.extension:valueCategory",
        "path": "Extension.extension.extension.extension",
        "sliceName": "valueCategory",
        "short": "R5: Description for grouping of ordinal or polychotomous variables (new)",
        "definition": "R5: `Evidence.statistic.modelCharacteristic.variable.valueCategory` (new:CodeableConcept)",
        "comment": "Element `Evidence.statistic.modelCharacteristic.variable.valueCategory` is part of an existing definition because parent element `Evidence.statistic.modelCharacteristic.variable` requires a cross-version extension.\nElement `Evidence.statistic.modelCharacteristic.variable.valueCategory` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.modelCharacteristic.variable.valueCategory` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
        "requirements": "Element `Evidence.statistic.modelCharacteristic.variable.valueCategory` is part of an existing definition because parent element `Evidence.statistic.modelCharacteristic.variable` requires a cross-version extension.\nElement `Evidence.statistic.modelCharacteristic.variable.valueCategory` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.modelCharacteristic.variable.valueCategory` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
        "min": 0,
        "max": "*",
        "base": {
          "path": "Element.extension",
          "min": 0,
          "max": "*"
        },
        "type": [
          {
            "code": "Extension"
          }
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element|4.0.1"
          },
          {
            "key": "ext-1",
            "severity": "error",
            "human": "Must have either extensions or value[x], not both",
            "expression": "extension.exists() != value.exists()",
            "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
            "source": "http://hl7.org/fhir/StructureDefinition/Extension|4.0.1"
          }
        ],
        "isModifier": false,
        "isSummary": false
      },
      {
        "id": "Extension.extension:modelCharacteristic.extension:variable.extension:valueCategory.id",
        "path": "Extension.extension.extension.extension.id",
        "representation": [
          "xmlAttr"
        ],
        "short": "Unique id for inter-element referencing",
        "definition": "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Element.id",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
                "valueUrl": "string"
              }
            ],
            "code": "http://hl7.org/fhirpath/System.String"
          }
        ],
        "isModifier": false,
        "isSummary": false,
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          }
        ]
      },
      {
        "id": "Extension.extension:modelCharacteristic.extension:variable.extension:valueCategory.extension",
        "path": "Extension.extension.extension.extension.extension",
        "slicing": {
          "discriminator": [
            {
              "type": "value",
              "path": "url"
            }
          ],
          "description": "Extensions are always sliced by (at least) url",
          "rules": "open"
        },
        "short": "Additional content defined by implementations",
        "definition": "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance  applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.",
        "comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
        "alias": [
          "extensions",
          "user content"
        ],
        "min": 0,
        "max": "*",
        "base": {
          "path": "Element.extension",
          "min": 0,
          "max": "*"
        },
        "type": [
          {
            "code": "Extension"
          }
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element|4.0.1"
          },
          {
            "key": "ext-1",
            "severity": "error",
            "human": "Must have either extensions or value[x], not both",
            "expression": "extension.exists() != value.exists()",
            "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
            "source": "http://hl7.org/fhir/StructureDefinition/Extension|4.0.1"
          }
        ],
        "isModifier": false,
        "isSummary": false,
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          }
        ]
      },
      {
        "id": "Extension.extension:modelCharacteristic.extension:variable.extension:valueCategory.url",
        "path": "Extension.extension.extension.extension.url",
        "representation": [
          "xmlAttr"
        ],
        "short": "identifies the meaning of the extension",
        "definition": "Source of the definition for the extension code - a logical name or a URL.",
        "comment": "The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.",
        "min": 1,
        "max": "1",
        "base": {
          "path": "Extension.url",
          "min": 1,
          "max": "1"
        },
        "type": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
                "valueUrl": "uri"
              }
            ],
            "code": "http://hl7.org/fhirpath/System.String"
          }
        ],
        "fixedUri": "valueCategory",
        "isModifier": false,
        "isSummary": false,
        "mapping": [
          {
            "identity": "rim",
            "map": "N/A"
          }
        ]
      },
      {
        "id": "Extension.extension:modelCharacteristic.extension:variable.extension:valueCategory.value[x]",
        "path": "Extension.extension.extension.extension.value[x]",
        "short": "Description for grouping of ordinal or polychotomous variables",
        "definition": "Description for grouping of ordinal or polychotomous variables.",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Extension.value[x]",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "CodeableConcept"
          }
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element|4.0.1"
          }
        ],
        "isModifier": false,
        "isSummary": false,
        "mapping": [
          {
            "identity": "rim",
            "map": "N/A"
          }
        ]
      },
      {
        "id": "Extension.extension:modelCharacteristic.extension:variable.extension:valueQuantity",
        "path": "Extension.extension.extension.extension",
        "sliceName": "valueQuantity",
        "short": "R5: Discrete value for grouping of ordinal or polychotomous variables (new)",
        "definition": "R5: `Evidence.statistic.modelCharacteristic.variable.valueQuantity` (new:Quantity)",
        "comment": "Element `Evidence.statistic.modelCharacteristic.variable.valueQuantity` is part of an existing definition because parent element `Evidence.statistic.modelCharacteristic.variable` requires a cross-version extension.\nElement `Evidence.statistic.modelCharacteristic.variable.valueQuantity` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.modelCharacteristic.variable.valueQuantity` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
        "requirements": "Element `Evidence.statistic.modelCharacteristic.variable.valueQuantity` is part of an existing definition because parent element `Evidence.statistic.modelCharacteristic.variable` requires a cross-version extension.\nElement `Evidence.statistic.modelCharacteristic.variable.valueQuantity` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.modelCharacteristic.variable.valueQuantity` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
        "min": 0,
        "max": "*",
        "base": {
          "path": "Element.extension",
          "min": 0,
          "max": "*"
        },
        "type": [
          {
            "code": "Extension"
          }
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element|4.0.1"
          },
          {
            "key": "ext-1",
            "severity": "error",
            "human": "Must have either extensions or value[x], not both",
            "expression": "extension.exists() != value.exists()",
            "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
            "source": "http://hl7.org/fhir/StructureDefinition/Extension|4.0.1"
          }
        ],
        "isModifier": false,
        "isSummary": false
      },
      {
        "id": "Extension.extension:modelCharacteristic.extension:variable.extension:valueQuantity.id",
        "path": "Extension.extension.extension.extension.id",
        "representation": [
          "xmlAttr"
        ],
        "short": "Unique id for inter-element referencing",
        "definition": "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Element.id",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
                "valueUrl": "string"
              }
            ],
            "code": "http://hl7.org/fhirpath/System.String"
          }
        ],
        "isModifier": false,
        "isSummary": false,
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          }
        ]
      },
      {
        "id": "Extension.extension:modelCharacteristic.extension:variable.extension:valueQuantity.extension",
        "path": "Extension.extension.extension.extension.extension",
        "slicing": {
          "discriminator": [
            {
              "type": "value",
              "path": "url"
            }
          ],
          "description": "Extensions are always sliced by (at least) url",
          "rules": "open"
        },
        "short": "Additional content defined by implementations",
        "definition": "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance  applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.",
        "comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
        "alias": [
          "extensions",
          "user content"
        ],
        "min": 0,
        "max": "*",
        "base": {
          "path": "Element.extension",
          "min": 0,
          "max": "*"
        },
        "type": [
          {
            "code": "Extension"
          }
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element|4.0.1"
          },
          {
            "key": "ext-1",
            "severity": "error",
            "human": "Must have either extensions or value[x], not both",
            "expression": "extension.exists() != value.exists()",
            "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
            "source": "http://hl7.org/fhir/StructureDefinition/Extension|4.0.1"
          }
        ],
        "isModifier": false,
        "isSummary": false,
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          }
        ]
      },
      {
        "id": "Extension.extension:modelCharacteristic.extension:variable.extension:valueQuantity.url",
        "path": "Extension.extension.extension.extension.url",
        "representation": [
          "xmlAttr"
        ],
        "short": "identifies the meaning of the extension",
        "definition": "Source of the definition for the extension code - a logical name or a URL.",
        "comment": "The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.",
        "min": 1,
        "max": "1",
        "base": {
          "path": "Extension.url",
          "min": 1,
          "max": "1"
        },
        "type": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
                "valueUrl": "uri"
              }
            ],
            "code": "http://hl7.org/fhirpath/System.String"
          }
        ],
        "fixedUri": "valueQuantity",
        "isModifier": false,
        "isSummary": false,
        "mapping": [
          {
            "identity": "rim",
            "map": "N/A"
          }
        ]
      },
      {
        "id": "Extension.extension:modelCharacteristic.extension:variable.extension:valueQuantity.value[x]",
        "path": "Extension.extension.extension.extension.value[x]",
        "short": "Discrete value for grouping of ordinal or polychotomous variables",
        "definition": "Discrete value for grouping of ordinal or polychotomous variables.",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Extension.value[x]",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "Quantity"
          }
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element|4.0.1"
          }
        ],
        "isModifier": false,
        "isSummary": false,
        "mapping": [
          {
            "identity": "rim",
            "map": "N/A"
          }
        ]
      },
      {
        "id": "Extension.extension:modelCharacteristic.extension:variable.extension:valueRange",
        "path": "Extension.extension.extension.extension",
        "sliceName": "valueRange",
        "short": "R5: Range of values for grouping of ordinal or polychotomous variables (new)",
        "definition": "R5: `Evidence.statistic.modelCharacteristic.variable.valueRange` (new:Range)",
        "comment": "Element `Evidence.statistic.modelCharacteristic.variable.valueRange` is part of an existing definition because parent element `Evidence.statistic.modelCharacteristic.variable` requires a cross-version extension.\nElement `Evidence.statistic.modelCharacteristic.variable.valueRange` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.modelCharacteristic.variable.valueRange` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
        "requirements": "Element `Evidence.statistic.modelCharacteristic.variable.valueRange` is part of an existing definition because parent element `Evidence.statistic.modelCharacteristic.variable` requires a cross-version extension.\nElement `Evidence.statistic.modelCharacteristic.variable.valueRange` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.modelCharacteristic.variable.valueRange` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
        "min": 0,
        "max": "*",
        "base": {
          "path": "Element.extension",
          "min": 0,
          "max": "*"
        },
        "type": [
          {
            "code": "Extension"
          }
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element|4.0.1"
          },
          {
            "key": "ext-1",
            "severity": "error",
            "human": "Must have either extensions or value[x], not both",
            "expression": "extension.exists() != value.exists()",
            "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
            "source": "http://hl7.org/fhir/StructureDefinition/Extension|4.0.1"
          }
        ],
        "isModifier": false,
        "isSummary": false
      },
      {
        "id": "Extension.extension:modelCharacteristic.extension:variable.extension:valueRange.id",
        "path": "Extension.extension.extension.extension.id",
        "representation": [
          "xmlAttr"
        ],
        "short": "Unique id for inter-element referencing",
        "definition": "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Element.id",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
                "valueUrl": "string"
              }
            ],
            "code": "http://hl7.org/fhirpath/System.String"
          }
        ],
        "isModifier": false,
        "isSummary": false,
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          }
        ]
      },
      {
        "id": "Extension.extension:modelCharacteristic.extension:variable.extension:valueRange.extension",
        "path": "Extension.extension.extension.extension.extension",
        "slicing": {
          "discriminator": [
            {
              "type": "value",
              "path": "url"
            }
          ],
          "description": "Extensions are always sliced by (at least) url",
          "rules": "open"
        },
        "short": "Additional content defined by implementations",
        "definition": "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance  applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.",
        "comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
        "alias": [
          "extensions",
          "user content"
        ],
        "min": 0,
        "max": "*",
        "base": {
          "path": "Element.extension",
          "min": 0,
          "max": "*"
        },
        "type": [
          {
            "code": "Extension"
          }
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element|4.0.1"
          },
          {
            "key": "ext-1",
            "severity": "error",
            "human": "Must have either extensions or value[x], not both",
            "expression": "extension.exists() != value.exists()",
            "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
            "source": "http://hl7.org/fhir/StructureDefinition/Extension|4.0.1"
          }
        ],
        "isModifier": false,
        "isSummary": false,
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          }
        ]
      },
      {
        "id": "Extension.extension:modelCharacteristic.extension:variable.extension:valueRange.url",
        "path": "Extension.extension.extension.extension.url",
        "representation": [
          "xmlAttr"
        ],
        "short": "identifies the meaning of the extension",
        "definition": "Source of the definition for the extension code - a logical name or a URL.",
        "comment": "The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.",
        "min": 1,
        "max": "1",
        "base": {
          "path": "Extension.url",
          "min": 1,
          "max": "1"
        },
        "type": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
                "valueUrl": "uri"
              }
            ],
            "code": "http://hl7.org/fhirpath/System.String"
          }
        ],
        "fixedUri": "valueRange",
        "isModifier": false,
        "isSummary": false,
        "mapping": [
          {
            "identity": "rim",
            "map": "N/A"
          }
        ]
      },
      {
        "id": "Extension.extension:modelCharacteristic.extension:variable.extension:valueRange.value[x]",
        "path": "Extension.extension.extension.extension.value[x]",
        "short": "Range of values for grouping of ordinal or polychotomous variables",
        "definition": "Range of values for grouping of ordinal or polychotomous variables.",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Extension.value[x]",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "Range"
          }
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element|4.0.1"
          }
        ],
        "isModifier": false,
        "isSummary": false,
        "mapping": [
          {
            "identity": "rim",
            "map": "N/A"
          }
        ]
      },
      {
        "id": "Extension.extension:modelCharacteristic.extension:variable.url",
        "path": "Extension.extension.extension.url",
        "representation": [
          "xmlAttr"
        ],
        "short": "identifies the meaning of the extension",
        "definition": "Source of the definition for the extension code - a logical name or a URL.",
        "comment": "The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.",
        "min": 1,
        "max": "1",
        "base": {
          "path": "Extension.url",
          "min": 1,
          "max": "1"
        },
        "type": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
                "valueUrl": "uri"
              }
            ],
            "code": "http://hl7.org/fhirpath/System.String"
          }
        ],
        "fixedUri": "variable",
        "isModifier": false,
        "isSummary": false,
        "mapping": [
          {
            "identity": "rim",
            "map": "N/A"
          }
        ]
      },
      {
        "id": "Extension.extension:modelCharacteristic.extension:variable.value[x]",
        "path": "Extension.extension.extension.value[x]",
        "short": "Value of extension",
        "definition": "Value of extension - must be one of a constrained set of the data types (see [Extensibility](http://hl7.org/fhir/R4/extensibility.html) for a list).",
        "min": 0,
        "max": "0",
        "base": {
          "path": "Extension.value[x]",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "base64Binary"
          },
          {
            "code": "boolean"
          },
          {
            "code": "canonical"
          },
          {
            "code": "code"
          },
          {
            "code": "date"
          },
          {
            "code": "dateTime"
          },
          {
            "code": "decimal"
          },
          {
            "code": "id"
          },
          {
            "code": "instant"
          },
          {
            "code": "integer"
          },
          {
            "code": "markdown"
          },
          {
            "code": "oid"
          },
          {
            "code": "positiveInt"
          },
          {
            "code": "string"
          },
          {
            "code": "time"
          },
          {
            "code": "unsignedInt"
          },
          {
            "code": "uri"
          },
          {
            "code": "url"
          },
          {
            "code": "uuid"
          },
          {
            "code": "Address"
          },
          {
            "code": "Age"
          },
          {
            "code": "Annotation"
          },
          {
            "code": "Attachment"
          },
          {
            "code": "CodeableConcept"
          },
          {
            "code": "Coding"
          },
          {
            "code": "ContactPoint"
          },
          {
            "code": "Count"
          },
          {
            "code": "Distance"
          },
          {
            "code": "Duration"
          },
          {
            "code": "HumanName"
          },
          {
            "code": "Identifier"
          },
          {
            "code": "Money"
          },
          {
            "code": "Period"
          },
          {
            "code": "Quantity"
          },
          {
            "code": "Range"
          },
          {
            "code": "Ratio"
          },
          {
            "code": "Reference"
          },
          {
            "code": "SampledData"
          },
          {
            "code": "Signature"
          },
          {
            "code": "Timing"
          },
          {
            "code": "ContactDetail"
          },
          {
            "code": "Contributor"
          },
          {
            "code": "DataRequirement"
          },
          {
            "code": "Expression"
          },
          {
            "code": "ParameterDefinition"
          },
          {
            "code": "RelatedArtifact"
          },
          {
            "code": "TriggerDefinition"
          },
          {
            "code": "UsageContext"
          },
          {
            "code": "Dosage"
          },
          {
            "code": "Meta"
          }
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element|4.0.1"
          }
        ],
        "isModifier": false,
        "isSummary": false,
        "mapping": [
          {
            "identity": "rim",
            "map": "N/A"
          }
        ]
      },
      {
        "id": "Extension.extension:modelCharacteristic.extension:attributeEstimate",
        "path": "Extension.extension.extension",
        "sliceName": "attributeEstimate",
        "short": "R5: An attribute of the statistic used as a model characteristic (new)",
        "definition": "R5: `Evidence.statistic.modelCharacteristic.attributeEstimate` (new:Evidence.statistic.attributeEstimate)",
        "comment": "Element `Evidence.statistic.modelCharacteristic.attributeEstimate` is part of an existing definition because parent element `Evidence.statistic.modelCharacteristic` requires a cross-version extension.\nElement `Evidence.statistic.modelCharacteristic.attributeEstimate` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.modelCharacteristic.attributeEstimate` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
        "requirements": "Element `Evidence.statistic.modelCharacteristic.attributeEstimate` is part of an existing definition because parent element `Evidence.statistic.modelCharacteristic` requires a cross-version extension.\nElement `Evidence.statistic.modelCharacteristic.attributeEstimate` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.modelCharacteristic.attributeEstimate` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
        "min": 0,
        "max": "*",
        "base": {
          "path": "Element.extension",
          "min": 0,
          "max": "*"
        },
        "type": [
          {
            "code": "Extension"
          }
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element|4.0.1"
          },
          {
            "key": "ext-1",
            "severity": "error",
            "human": "Must have either extensions or value[x], not both",
            "expression": "extension.exists() != value.exists()",
            "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
            "source": "http://hl7.org/fhir/StructureDefinition/Extension|4.0.1"
          }
        ],
        "isModifier": false,
        "isSummary": false
      },
      {
        "id": "Extension.extension:modelCharacteristic.extension:attributeEstimate.id",
        "path": "Extension.extension.extension.id",
        "representation": [
          "xmlAttr"
        ],
        "short": "Unique id for inter-element referencing",
        "definition": "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Element.id",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
                "valueUrl": "string"
              }
            ],
            "code": "http://hl7.org/fhirpath/System.String"
          }
        ],
        "isModifier": false,
        "isSummary": false,
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          }
        ]
      },
      {
        "id": "Extension.extension:modelCharacteristic.extension:attributeEstimate.extension",
        "path": "Extension.extension.extension.extension",
        "slicing": {
          "discriminator": [
            {
              "type": "value",
              "path": "url"
            }
          ],
          "description": "Extensions are always sliced by (at least) url",
          "rules": "open"
        },
        "short": "Additional content defined by implementations",
        "definition": "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance  applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.",
        "comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
        "alias": [
          "extensions",
          "user content"
        ],
        "min": 0,
        "max": "*",
        "base": {
          "path": "Element.extension",
          "min": 0,
          "max": "*"
        },
        "type": [
          {
            "code": "Extension"
          }
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element|4.0.1"
          },
          {
            "key": "ext-1",
            "severity": "error",
            "human": "Must have either extensions or value[x], not both",
            "expression": "extension.exists() != value.exists()",
            "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
            "source": "http://hl7.org/fhir/StructureDefinition/Extension|4.0.1"
          }
        ],
        "isModifier": false,
        "isSummary": false,
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          }
        ]
      },
      {
        "id": "Extension.extension:modelCharacteristic.extension:attributeEstimate.url",
        "path": "Extension.extension.extension.url",
        "representation": [
          "xmlAttr"
        ],
        "short": "identifies the meaning of the extension",
        "definition": "Source of the definition for the extension code - a logical name or a URL.",
        "comment": "The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.",
        "min": 1,
        "max": "1",
        "base": {
          "path": "Extension.url",
          "min": 1,
          "max": "1"
        },
        "type": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
                "valueUrl": "uri"
              }
            ],
            "code": "http://hl7.org/fhirpath/System.String"
          }
        ],
        "fixedUri": "http://hl7.org/fhir/5.0/StructureDefinition/extension-Evidence.statistic.attributeEstimate",
        "isModifier": false,
        "isSummary": false,
        "mapping": [
          {
            "identity": "rim",
            "map": "N/A"
          }
        ]
      },
      {
        "id": "Extension.extension:modelCharacteristic.extension:attributeEstimate.value[x]",
        "path": "Extension.extension.extension.value[x]",
        "short": "Value of extension",
        "definition": "Value of extension - must be one of a constrained set of the data types (see [Extensibility](http://hl7.org/fhir/R4/extensibility.html) for a list).",
        "min": 0,
        "max": "0",
        "base": {
          "path": "Extension.value[x]",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "base64Binary"
          },
          {
            "code": "boolean"
          },
          {
            "code": "canonical"
          },
          {
            "code": "code"
          },
          {
            "code": "date"
          },
          {
            "code": "dateTime"
          },
          {
            "code": "decimal"
          },
          {
            "code": "id"
          },
          {
            "code": "instant"
          },
          {
            "code": "integer"
          },
          {
            "code": "markdown"
          },
          {
            "code": "oid"
          },
          {
            "code": "positiveInt"
          },
          {
            "code": "string"
          },
          {
            "code": "time"
          },
          {
            "code": "unsignedInt"
          },
          {
            "code": "uri"
          },
          {
            "code": "url"
          },
          {
            "code": "uuid"
          },
          {
            "code": "Address"
          },
          {
            "code": "Age"
          },
          {
            "code": "Annotation"
          },
          {
            "code": "Attachment"
          },
          {
            "code": "CodeableConcept"
          },
          {
            "code": "Coding"
          },
          {
            "code": "ContactPoint"
          },
          {
            "code": "Count"
          },
          {
            "code": "Distance"
          },
          {
            "code": "Duration"
          },
          {
            "code": "HumanName"
          },
          {
            "code": "Identifier"
          },
          {
            "code": "Money"
          },
          {
            "code": "Period"
          },
          {
            "code": "Quantity"
          },
          {
            "code": "Range"
          },
          {
            "code": "Ratio"
          },
          {
            "code": "Reference"
          },
          {
            "code": "SampledData"
          },
          {
            "code": "Signature"
          },
          {
            "code": "Timing"
          },
          {
            "code": "ContactDetail"
          },
          {
            "code": "Contributor"
          },
          {
            "code": "DataRequirement"
          },
          {
            "code": "Expression"
          },
          {
            "code": "ParameterDefinition"
          },
          {
            "code": "RelatedArtifact"
          },
          {
            "code": "TriggerDefinition"
          },
          {
            "code": "UsageContext"
          },
          {
            "code": "Dosage"
          },
          {
            "code": "Meta"
          }
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element|4.0.1"
          }
        ],
        "isModifier": false,
        "isSummary": false,
        "mapping": [
          {
            "identity": "rim",
            "map": "N/A"
          }
        ]
      },
      {
        "id": "Extension.extension:modelCharacteristic.url",
        "path": "Extension.extension.url",
        "representation": [
          "xmlAttr"
        ],
        "short": "identifies the meaning of the extension",
        "definition": "Source of the definition for the extension code - a logical name or a URL.",
        "comment": "The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.",
        "min": 1,
        "max": "1",
        "base": {
          "path": "Extension.url",
          "min": 1,
          "max": "1"
        },
        "type": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
                "valueUrl": "uri"
              }
            ],
            "code": "http://hl7.org/fhirpath/System.String"
          }
        ],
        "fixedUri": "modelCharacteristic",
        "isModifier": false,
        "isSummary": false,
        "mapping": [
          {
            "identity": "rim",
            "map": "N/A"
          }
        ]
      },
      {
        "id": "Extension.extension:modelCharacteristic.value[x]",
        "path": "Extension.extension.value[x]",
        "short": "Value of extension",
        "definition": "Value of extension - must be one of a constrained set of the data types (see [Extensibility](http://hl7.org/fhir/R4/extensibility.html) for a list).",
        "min": 0,
        "max": "0",
        "base": {
          "path": "Extension.value[x]",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "base64Binary"
          },
          {
            "code": "boolean"
          },
          {
            "code": "canonical"
          },
          {
            "code": "code"
          },
          {
            "code": "date"
          },
          {
            "code": "dateTime"
          },
          {
            "code": "decimal"
          },
          {
            "code": "id"
          },
          {
            "code": "instant"
          },
          {
            "code": "integer"
          },
          {
            "code": "markdown"
          },
          {
            "code": "oid"
          },
          {
            "code": "positiveInt"
          },
          {
            "code": "string"
          },
          {
            "code": "time"
          },
          {
            "code": "unsignedInt"
          },
          {
            "code": "uri"
          },
          {
            "code": "url"
          },
          {
            "code": "uuid"
          },
          {
            "code": "Address"
          },
          {
            "code": "Age"
          },
          {
            "code": "Annotation"
          },
          {
            "code": "Attachment"
          },
          {
            "code": "CodeableConcept"
          },
          {
            "code": "Coding"
          },
          {
            "code": "ContactPoint"
          },
          {
            "code": "Count"
          },
          {
            "code": "Distance"
          },
          {
            "code": "Duration"
          },
          {
            "code": "HumanName"
          },
          {
            "code": "Identifier"
          },
          {
            "code": "Money"
          },
          {
            "code": "Period"
          },
          {
            "code": "Quantity"
          },
          {
            "code": "Range"
          },
          {
            "code": "Ratio"
          },
          {
            "code": "Reference"
          },
          {
            "code": "SampledData"
          },
          {
            "code": "Signature"
          },
          {
            "code": "Timing"
          },
          {
            "code": "ContactDetail"
          },
          {
            "code": "Contributor"
          },
          {
            "code": "DataRequirement"
          },
          {
            "code": "Expression"
          },
          {
            "code": "ParameterDefinition"
          },
          {
            "code": "RelatedArtifact"
          },
          {
            "code": "TriggerDefinition"
          },
          {
            "code": "UsageContext"
          },
          {
            "code": "Dosage"
          },
          {
            "code": "Meta"
          }
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element|4.0.1"
          }
        ],
        "isModifier": false,
        "isSummary": false,
        "mapping": [
          {
            "identity": "rim",
            "map": "N/A"
          }
        ]
      },
      {
        "id": "Extension.url",
        "path": "Extension.url",
        "representation": [
          "xmlAttr"
        ],
        "short": "identifies the meaning of the extension",
        "definition": "Source of the definition for the extension code - a logical name or a URL.",
        "comment": "The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.",
        "min": 1,
        "max": "1",
        "base": {
          "path": "Extension.url",
          "min": 1,
          "max": "1"
        },
        "type": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
                "valueUrl": "uri"
              }
            ],
            "code": "http://hl7.org/fhirpath/System.String"
          }
        ],
        "fixedUri": "http://hl7.org/fhir/5.0/StructureDefinition/extension-Evidence.statistic",
        "isModifier": false,
        "isSummary": false,
        "mapping": [
          {
            "identity": "rim",
            "map": "N/A"
          }
        ]
      },
      {
        "id": "Extension.value[x]",
        "path": "Extension.value[x]",
        "short": "Value of extension",
        "definition": "Value of extension - must be one of a constrained set of the data types (see [Extensibility](http://hl7.org/fhir/R4/extensibility.html) for a list).",
        "min": 0,
        "max": "0",
        "base": {
          "path": "Extension.value[x]",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "base64Binary"
          },
          {
            "code": "boolean"
          },
          {
            "code": "canonical"
          },
          {
            "code": "code"
          },
          {
            "code": "date"
          },
          {
            "code": "dateTime"
          },
          {
            "code": "decimal"
          },
          {
            "code": "id"
          },
          {
            "code": "instant"
          },
          {
            "code": "integer"
          },
          {
            "code": "markdown"
          },
          {
            "code": "oid"
          },
          {
            "code": "positiveInt"
          },
          {
            "code": "string"
          },
          {
            "code": "time"
          },
          {
            "code": "unsignedInt"
          },
          {
            "code": "uri"
          },
          {
            "code": "url"
          },
          {
            "code": "uuid"
          },
          {
            "code": "Address"
          },
          {
            "code": "Age"
          },
          {
            "code": "Annotation"
          },
          {
            "code": "Attachment"
          },
          {
            "code": "CodeableConcept"
          },
          {
            "code": "Coding"
          },
          {
            "code": "ContactPoint"
          },
          {
            "code": "Count"
          },
          {
            "code": "Distance"
          },
          {
            "code": "Duration"
          },
          {
            "code": "HumanName"
          },
          {
            "code": "Identifier"
          },
          {
            "code": "Money"
          },
          {
            "code": "Period"
          },
          {
            "code": "Quantity"
          },
          {
            "code": "Range"
          },
          {
            "code": "Ratio"
          },
          {
            "code": "Reference"
          },
          {
            "code": "SampledData"
          },
          {
            "code": "Signature"
          },
          {
            "code": "Timing"
          },
          {
            "code": "ContactDetail"
          },
          {
            "code": "Contributor"
          },
          {
            "code": "DataRequirement"
          },
          {
            "code": "Expression"
          },
          {
            "code": "ParameterDefinition"
          },
          {
            "code": "RelatedArtifact"
          },
          {
            "code": "TriggerDefinition"
          },
          {
            "code": "UsageContext"
          },
          {
            "code": "Dosage"
          },
          {
            "code": "Meta"
          }
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element|4.0.1"
          }
        ],
        "isModifier": false,
        "isSummary": false,
        "mapping": [
          {
            "identity": "rim",
            "map": "N/A"
          }
        ]
      }
    ]
  },
  "differential": {
    "element": [
      {
        "id": "Extension",
        "path": "Extension",
        "short": "R5: Values and parameters for a single statistic (new)",
        "definition": "R5: `Evidence.statistic` (new:BackboneElement)",
        "comment": "Element `Evidence.statistic` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
        "min": 0,
        "max": "*",
        "base": {
          "path": "Extension",
          "min": 0,
          "max": "*"
        },
        "isModifier": false
      },
      {
        "id": "Extension.extension",
        "path": "Extension.extension",
        "slicing": {
          "discriminator": [
            {
              "type": "value",
              "path": "url"
            }
          ],
          "ordered": false,
          "rules": "open"
        },
        "min": 0,
        "max": "*",
        "base": {
          "path": "Extension.extension",
          "min": 0,
          "max": "*"
        }
      },
      {
        "id": "Extension.extension:description",
        "path": "Extension.extension",
        "sliceName": "description",
        "short": "R5: Description of content (new)",
        "definition": "R5: `Evidence.statistic.description` (new:markdown)",
        "comment": "Element `Evidence.statistic.description` is part of an existing definition because parent element `Evidence.statistic` requires a cross-version extension.\nElement `Evidence.statistic.description` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.description` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
        "requirements": "Element `Evidence.statistic.description` is part of an existing definition because parent element `Evidence.statistic` requires a cross-version extension.\nElement `Evidence.statistic.description` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.description` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Extension.extension",
          "min": 0,
          "max": "*"
        }
      },
      {
        "id": "Extension.extension:description.url",
        "path": "Extension.extension.url",
        "min": 1,
        "max": "1",
        "base": {
          "path": "Extension.url",
          "min": 1,
          "max": "1"
        },
        "fixedUri": "description"
      },
      {
        "id": "Extension.extension:description.value[x]",
        "path": "Extension.extension.value[x]",
        "short": "Description of content",
        "definition": "A description of the content value of the statistic.",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Extension.value[x]",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "markdown"
          }
        ]
      },
      {
        "id": "Extension.extension:note",
        "path": "Extension.extension",
        "sliceName": "note",
        "short": "R5: Footnotes and/or explanatory notes (new)",
        "definition": "R5: `Evidence.statistic.note` (new:Annotation)",
        "comment": "Element `Evidence.statistic.note` is part of an existing definition because parent element `Evidence.statistic` requires a cross-version extension.\nElement `Evidence.statistic.note` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.note` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
        "requirements": "Element `Evidence.statistic.note` is part of an existing definition because parent element `Evidence.statistic` requires a cross-version extension.\nElement `Evidence.statistic.note` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.note` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
        "min": 0,
        "max": "*",
        "base": {
          "path": "Extension.extension",
          "min": 0,
          "max": "*"
        }
      },
      {
        "id": "Extension.extension:note.url",
        "path": "Extension.extension.url",
        "min": 1,
        "max": "1",
        "base": {
          "path": "Extension.url",
          "min": 1,
          "max": "1"
        },
        "fixedUri": "note"
      },
      {
        "id": "Extension.extension:note.value[x]",
        "path": "Extension.extension.value[x]",
        "short": "Footnotes and/or explanatory notes",
        "definition": "Footnotes and/or explanatory notes.",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Extension.value[x]",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "Annotation"
          }
        ]
      },
      {
        "id": "Extension.extension:statisticType",
        "path": "Extension.extension",
        "sliceName": "statisticType",
        "short": "R5: Type of statistic, e.g., relative risk (new)",
        "definition": "R5: `Evidence.statistic.statisticType` (new:CodeableConcept)",
        "comment": "Element `Evidence.statistic.statisticType` is part of an existing definition because parent element `Evidence.statistic` requires a cross-version extension.\nElement `Evidence.statistic.statisticType` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.statisticType` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
        "requirements": "Element `Evidence.statistic.statisticType` is part of an existing definition because parent element `Evidence.statistic` requires a cross-version extension.\nElement `Evidence.statistic.statisticType` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.statisticType` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Extension.extension",
          "min": 0,
          "max": "*"
        }
      },
      {
        "id": "Extension.extension:statisticType.url",
        "path": "Extension.extension.url",
        "min": 1,
        "max": "1",
        "base": {
          "path": "Extension.url",
          "min": 1,
          "max": "1"
        },
        "fixedUri": "statisticType"
      },
      {
        "id": "Extension.extension:statisticType.value[x]",
        "path": "Extension.extension.value[x]",
        "short": "Type of statistic, e.g., relative risk",
        "definition": "Type of statistic, e.g., relative risk.",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Extension.value[x]",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "CodeableConcept"
          }
        ],
        "binding": {
          "strength": "extensible",
          "valueSet": "http://hl7.org/fhir/uv/xver/ValueSet/R5-statistic-type-for-R4|0.1.0"
        }
      },
      {
        "id": "Extension.extension:category",
        "path": "Extension.extension",
        "sliceName": "category",
        "short": "R5: Associated category for categorical variable (new)",
        "definition": "R5: `Evidence.statistic.category` (new:CodeableConcept)",
        "comment": "Element `Evidence.statistic.category` is part of an existing definition because parent element `Evidence.statistic` requires a cross-version extension.\nElement `Evidence.statistic.category` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.category` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).\nSimple strings can be used for descriptive purposes. Exact matching to EvidenceVariable.category.name for the Evidence.variableDefinition[variableRole=measuredVariable].observed=Reference(EvidenceVariable) could facilitate validation within datasets.",
        "requirements": "Element `Evidence.statistic.category` is part of an existing definition because parent element `Evidence.statistic` requires a cross-version extension.\nElement `Evidence.statistic.category` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.category` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Extension.extension",
          "min": 0,
          "max": "*"
        }
      },
      {
        "id": "Extension.extension:category.url",
        "path": "Extension.extension.url",
        "min": 1,
        "max": "1",
        "base": {
          "path": "Extension.url",
          "min": 1,
          "max": "1"
        },
        "fixedUri": "category"
      },
      {
        "id": "Extension.extension:category.value[x]",
        "path": "Extension.extension.value[x]",
        "short": "Associated category for categorical variable",
        "definition": "When the measured variable is handled categorically, the category element is used to define which category the statistic is reporting.",
        "comment": "Simple strings can be used for descriptive purposes. Exact matching to EvidenceVariable.category.name for the Evidence.variableDefinition[variableRole=measuredVariable].observed=Reference(EvidenceVariable) could facilitate validation within datasets.",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Extension.value[x]",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "CodeableConcept"
          }
        ]
      },
      {
        "id": "Extension.extension:quantity",
        "path": "Extension.extension",
        "sliceName": "quantity",
        "short": "R5: Statistic value (new)",
        "definition": "R5: `Evidence.statistic.quantity` (new:Quantity)",
        "comment": "Element `Evidence.statistic.quantity` is part of an existing definition because parent element `Evidence.statistic` requires a cross-version extension.\nElement `Evidence.statistic.quantity` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.quantity` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
        "requirements": "Element `Evidence.statistic.quantity` is part of an existing definition because parent element `Evidence.statistic` requires a cross-version extension.\nElement `Evidence.statistic.quantity` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.quantity` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Extension.extension",
          "min": 0,
          "max": "*"
        }
      },
      {
        "id": "Extension.extension:quantity.url",
        "path": "Extension.extension.url",
        "min": 1,
        "max": "1",
        "base": {
          "path": "Extension.url",
          "min": 1,
          "max": "1"
        },
        "fixedUri": "quantity"
      },
      {
        "id": "Extension.extension:quantity.value[x]",
        "path": "Extension.extension.value[x]",
        "short": "Statistic value",
        "definition": "Statistic value.",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Extension.value[x]",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "Quantity"
          }
        ]
      },
      {
        "id": "Extension.extension:numberOfEvents",
        "path": "Extension.extension",
        "sliceName": "numberOfEvents",
        "short": "R5: The number of events associated with the statistic (new)",
        "definition": "R5: `Evidence.statistic.numberOfEvents` (new:unsignedInt)",
        "comment": "Element `Evidence.statistic.numberOfEvents` is part of an existing definition because parent element `Evidence.statistic` requires a cross-version extension.\nElement `Evidence.statistic.numberOfEvents` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.numberOfEvents` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).\nWhen the number of events is the statistic, use Evidence.statistic.quantity and set Evidence.statistic.type.coding.code=C25463 and Evidence.statistic.type.coding.display=Count. When the statistic is an Event Rate (where individual participants may have 2 or more events), use Evidence.statistic.numberOfEvents to record the total number of events rather than the number of participants with events.",
        "requirements": "Element `Evidence.statistic.numberOfEvents` is part of an existing definition because parent element `Evidence.statistic` requires a cross-version extension.\nElement `Evidence.statistic.numberOfEvents` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.numberOfEvents` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Extension.extension",
          "min": 0,
          "max": "*"
        }
      },
      {
        "id": "Extension.extension:numberOfEvents.url",
        "path": "Extension.extension.url",
        "min": 1,
        "max": "1",
        "base": {
          "path": "Extension.url",
          "min": 1,
          "max": "1"
        },
        "fixedUri": "numberOfEvents"
      },
      {
        "id": "Extension.extension:numberOfEvents.value[x]",
        "path": "Extension.extension.value[x]",
        "short": "The number of events associated with the statistic",
        "definition": "The number of events associated with the statistic, where the unit of analysis is different from numberAffected, sampleSize.knownDataCount and sampleSize.numberOfParticipants.",
        "comment": "When the number of events is the statistic, use Evidence.statistic.quantity and set Evidence.statistic.type.coding.code=C25463 and Evidence.statistic.type.coding.display=Count. When the statistic is an Event Rate (where individual participants may have 2 or more events), use Evidence.statistic.numberOfEvents to record the total number of events rather than the number of participants with events.",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Extension.value[x]",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "unsignedInt"
          }
        ]
      },
      {
        "id": "Extension.extension:numberAffected",
        "path": "Extension.extension",
        "sliceName": "numberAffected",
        "short": "R5: The number of participants affected (new)",
        "definition": "R5: `Evidence.statistic.numberAffected` (new:unsignedInt)",
        "comment": "Element `Evidence.statistic.numberAffected` is part of an existing definition because parent element `Evidence.statistic` requires a cross-version extension.\nElement `Evidence.statistic.numberAffected` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.numberAffected` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).\nWhen the number affected is the statistic, use Evidence.statistic.quantity and set Evidence.statistic.type.coding.code=C25463 and Evidence.statistic.type.coding.display=Count. When the statistic is a Proportion, use Evidence.statistic.numberAffected and enter an integer as the value. When the statistic is an Event Rate (where individual participants may have 2 or more events), use Evidence.statistic.numberAffected to record the number of participants with events rather than the total number of events.",
        "requirements": "Element `Evidence.statistic.numberAffected` is part of an existing definition because parent element `Evidence.statistic` requires a cross-version extension.\nElement `Evidence.statistic.numberAffected` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.numberAffected` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Extension.extension",
          "min": 0,
          "max": "*"
        }
      },
      {
        "id": "Extension.extension:numberAffected.url",
        "path": "Extension.extension.url",
        "min": 1,
        "max": "1",
        "base": {
          "path": "Extension.url",
          "min": 1,
          "max": "1"
        },
        "fixedUri": "numberAffected"
      },
      {
        "id": "Extension.extension:numberAffected.value[x]",
        "path": "Extension.extension.value[x]",
        "short": "The number of participants affected",
        "definition": "The number of participants affected where the unit of analysis is the same as sampleSize.knownDataCount and sampleSize.numberOfParticipants.",
        "comment": "When the number affected is the statistic, use Evidence.statistic.quantity and set Evidence.statistic.type.coding.code=C25463 and Evidence.statistic.type.coding.display=Count. When the statistic is a Proportion, use Evidence.statistic.numberAffected and enter an integer as the value. When the statistic is an Event Rate (where individual participants may have 2 or more events), use Evidence.statistic.numberAffected to record the number of participants with events rather than the total number of events.",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Extension.value[x]",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "unsignedInt"
          }
        ]
      },
      {
        "id": "Extension.extension:sampleSize",
        "path": "Extension.extension",
        "sliceName": "sampleSize",
        "short": "R5: Number of samples in the statistic (new)",
        "definition": "R5: `Evidence.statistic.sampleSize` (new:BackboneElement)",
        "comment": "Element `Evidence.statistic.sampleSize` is part of an existing definition because parent element `Evidence.statistic` requires a cross-version extension.\nElement `Evidence.statistic.sampleSize` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.sampleSize` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
        "requirements": "Element `Evidence.statistic.sampleSize` is part of an existing definition because parent element `Evidence.statistic` requires a cross-version extension.\nElement `Evidence.statistic.sampleSize` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.sampleSize` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Extension.extension",
          "min": 0,
          "max": "*"
        }
      },
      {
        "id": "Extension.extension:sampleSize.extension",
        "path": "Extension.extension.extension",
        "slicing": {
          "discriminator": [
            {
              "type": "value",
              "path": "url"
            }
          ],
          "ordered": false,
          "rules": "open"
        },
        "min": 0,
        "max": "*",
        "base": {
          "path": "Extension.extension",
          "min": 0,
          "max": "*"
        }
      },
      {
        "id": "Extension.extension:sampleSize.extension:description",
        "path": "Extension.extension.extension",
        "sliceName": "description",
        "short": "R5: Textual description of sample size for statistic (new)",
        "definition": "R5: `Evidence.statistic.sampleSize.description` (new:markdown)",
        "comment": "Element `Evidence.statistic.sampleSize.description` is part of an existing definition because parent element `Evidence.statistic.sampleSize` requires a cross-version extension.\nElement `Evidence.statistic.sampleSize.description` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.sampleSize.description` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
        "requirements": "Element `Evidence.statistic.sampleSize.description` is part of an existing definition because parent element `Evidence.statistic.sampleSize` requires a cross-version extension.\nElement `Evidence.statistic.sampleSize.description` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.sampleSize.description` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Extension.extension",
          "min": 0,
          "max": "*"
        }
      },
      {
        "id": "Extension.extension:sampleSize.extension:description.url",
        "path": "Extension.extension.extension.url",
        "min": 1,
        "max": "1",
        "base": {
          "path": "Extension.url",
          "min": 1,
          "max": "1"
        },
        "fixedUri": "description"
      },
      {
        "id": "Extension.extension:sampleSize.extension:description.value[x]",
        "path": "Extension.extension.extension.value[x]",
        "short": "Textual description of sample size for statistic",
        "definition": "Human-readable summary of population sample size.",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Extension.value[x]",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "markdown"
          }
        ]
      },
      {
        "id": "Extension.extension:sampleSize.extension:note",
        "path": "Extension.extension.extension",
        "sliceName": "note",
        "short": "R5: Footnote or explanatory note about the sample size (new)",
        "definition": "R5: `Evidence.statistic.sampleSize.note` (new:Annotation)",
        "comment": "Element `Evidence.statistic.sampleSize.note` is part of an existing definition because parent element `Evidence.statistic.sampleSize` requires a cross-version extension.\nElement `Evidence.statistic.sampleSize.note` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.sampleSize.note` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
        "requirements": "Element `Evidence.statistic.sampleSize.note` is part of an existing definition because parent element `Evidence.statistic.sampleSize` requires a cross-version extension.\nElement `Evidence.statistic.sampleSize.note` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.sampleSize.note` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
        "min": 0,
        "max": "*",
        "base": {
          "path": "Extension.extension",
          "min": 0,
          "max": "*"
        }
      },
      {
        "id": "Extension.extension:sampleSize.extension:note.url",
        "path": "Extension.extension.extension.url",
        "min": 1,
        "max": "1",
        "base": {
          "path": "Extension.url",
          "min": 1,
          "max": "1"
        },
        "fixedUri": "note"
      },
      {
        "id": "Extension.extension:sampleSize.extension:note.value[x]",
        "path": "Extension.extension.extension.value[x]",
        "short": "Footnote or explanatory note about the sample size",
        "definition": "Footnote or explanatory note about the sample size.",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Extension.value[x]",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "Annotation"
          }
        ]
      },
      {
        "id": "Extension.extension:sampleSize.extension:numberOfStudies",
        "path": "Extension.extension.extension",
        "sliceName": "numberOfStudies",
        "short": "R5: Number of contributing studies (new)",
        "definition": "R5: `Evidence.statistic.sampleSize.numberOfStudies` (new:unsignedInt)",
        "comment": "Element `Evidence.statistic.sampleSize.numberOfStudies` is part of an existing definition because parent element `Evidence.statistic.sampleSize` requires a cross-version extension.\nElement `Evidence.statistic.sampleSize.numberOfStudies` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.sampleSize.numberOfStudies` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
        "requirements": "Element `Evidence.statistic.sampleSize.numberOfStudies` is part of an existing definition because parent element `Evidence.statistic.sampleSize` requires a cross-version extension.\nElement `Evidence.statistic.sampleSize.numberOfStudies` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.sampleSize.numberOfStudies` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Extension.extension",
          "min": 0,
          "max": "*"
        }
      },
      {
        "id": "Extension.extension:sampleSize.extension:numberOfStudies.url",
        "path": "Extension.extension.extension.url",
        "min": 1,
        "max": "1",
        "base": {
          "path": "Extension.url",
          "min": 1,
          "max": "1"
        },
        "fixedUri": "numberOfStudies"
      },
      {
        "id": "Extension.extension:sampleSize.extension:numberOfStudies.value[x]",
        "path": "Extension.extension.extension.value[x]",
        "short": "Number of contributing studies",
        "definition": "Number of participants in the population.",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Extension.value[x]",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "unsignedInt"
          }
        ]
      },
      {
        "id": "Extension.extension:sampleSize.extension:numberOfParticipants",
        "path": "Extension.extension.extension",
        "sliceName": "numberOfParticipants",
        "short": "R5: Cumulative number of participants (new)",
        "definition": "R5: `Evidence.statistic.sampleSize.numberOfParticipants` (new:unsignedInt)",
        "comment": "Element `Evidence.statistic.sampleSize.numberOfParticipants` is part of an existing definition because parent element `Evidence.statistic.sampleSize` requires a cross-version extension.\nElement `Evidence.statistic.sampleSize.numberOfParticipants` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.sampleSize.numberOfParticipants` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
        "requirements": "Element `Evidence.statistic.sampleSize.numberOfParticipants` is part of an existing definition because parent element `Evidence.statistic.sampleSize` requires a cross-version extension.\nElement `Evidence.statistic.sampleSize.numberOfParticipants` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.sampleSize.numberOfParticipants` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Extension.extension",
          "min": 0,
          "max": "*"
        }
      },
      {
        "id": "Extension.extension:sampleSize.extension:numberOfParticipants.url",
        "path": "Extension.extension.extension.url",
        "min": 1,
        "max": "1",
        "base": {
          "path": "Extension.url",
          "min": 1,
          "max": "1"
        },
        "fixedUri": "numberOfParticipants"
      },
      {
        "id": "Extension.extension:sampleSize.extension:numberOfParticipants.value[x]",
        "path": "Extension.extension.extension.value[x]",
        "short": "Cumulative number of participants",
        "definition": "A human-readable string to clarify or explain concepts about the sample size.",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Extension.value[x]",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "unsignedInt"
          }
        ]
      },
      {
        "id": "Extension.extension:sampleSize.extension:knownDataCount",
        "path": "Extension.extension.extension",
        "sliceName": "knownDataCount",
        "short": "R5: Number of participants with known results for measured variables (new)",
        "definition": "R5: `Evidence.statistic.sampleSize.knownDataCount` (new:unsignedInt)",
        "comment": "Element `Evidence.statistic.sampleSize.knownDataCount` is part of an existing definition because parent element `Evidence.statistic.sampleSize` requires a cross-version extension.\nElement `Evidence.statistic.sampleSize.knownDataCount` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.sampleSize.knownDataCount` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
        "requirements": "Element `Evidence.statistic.sampleSize.knownDataCount` is part of an existing definition because parent element `Evidence.statistic.sampleSize` requires a cross-version extension.\nElement `Evidence.statistic.sampleSize.knownDataCount` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.sampleSize.knownDataCount` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Extension.extension",
          "min": 0,
          "max": "*"
        }
      },
      {
        "id": "Extension.extension:sampleSize.extension:knownDataCount.url",
        "path": "Extension.extension.extension.url",
        "min": 1,
        "max": "1",
        "base": {
          "path": "Extension.url",
          "min": 1,
          "max": "1"
        },
        "fixedUri": "knownDataCount"
      },
      {
        "id": "Extension.extension:sampleSize.extension:knownDataCount.value[x]",
        "path": "Extension.extension.extension.value[x]",
        "short": "Number of participants with known results for measured variables",
        "definition": "Number of participants with known results for measured variables.",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Extension.value[x]",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "unsignedInt"
          }
        ]
      },
      {
        "id": "Extension.extension:sampleSize.url",
        "path": "Extension.extension.url",
        "min": 1,
        "max": "1",
        "base": {
          "path": "Extension.url",
          "min": 1,
          "max": "1"
        },
        "fixedUri": "sampleSize"
      },
      {
        "id": "Extension.extension:sampleSize.value[x]",
        "path": "Extension.extension.value[x]",
        "min": 0,
        "max": "0",
        "base": {
          "path": "Extension.value[x]",
          "min": 0,
          "max": "1"
        }
      },
      {
        "id": "Extension.extension:attributeEstimate",
        "path": "Extension.extension",
        "sliceName": "attributeEstimate",
        "short": "R5: An attribute of the Statistic (new)",
        "definition": "R5: `Evidence.statistic.attributeEstimate` (new:BackboneElement)",
        "comment": "Element `Evidence.statistic.attributeEstimate` is part of an existing definition because parent element `Evidence.statistic` requires a cross-version extension.\nElement `Evidence.statistic.attributeEstimate` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.attributeEstimate` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
        "requirements": "Element `Evidence.statistic.attributeEstimate` is part of an existing definition because parent element `Evidence.statistic` requires a cross-version extension.\nElement `Evidence.statistic.attributeEstimate` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.attributeEstimate` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).\nCreating extension because element `Evidence.statistic.attributeEstimate` is a content reference and requires an extesion definition.",
        "min": 0,
        "max": "*",
        "base": {
          "path": "Extension.extension",
          "min": 0,
          "max": "*"
        }
      },
      {
        "id": "Extension.extension:attributeEstimate.extension",
        "path": "Extension.extension.extension",
        "slicing": {
          "discriminator": [
            {
              "type": "value",
              "path": "url"
            }
          ],
          "ordered": false,
          "rules": "open"
        },
        "min": 0,
        "max": "*",
        "base": {
          "path": "Extension.extension",
          "min": 0,
          "max": "*"
        }
      },
      {
        "id": "Extension.extension:attributeEstimate.extension:description",
        "path": "Extension.extension.extension",
        "sliceName": "description",
        "short": "R5: Textual description of the attribute estimate (new)",
        "definition": "R5: `Evidence.statistic.attributeEstimate.description` (new:markdown)",
        "comment": "Element `Evidence.statistic.attributeEstimate.description` is part of an existing definition because parent element `Evidence.statistic.attributeEstimate` requires a cross-version extension.\nElement `Evidence.statistic.attributeEstimate.description` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.attributeEstimate.description` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
        "requirements": "Element `Evidence.statistic.attributeEstimate.description` is part of an existing definition because parent element `Evidence.statistic.attributeEstimate` requires a cross-version extension.\nElement `Evidence.statistic.attributeEstimate.description` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.attributeEstimate.description` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Extension.extension",
          "min": 0,
          "max": "*"
        }
      },
      {
        "id": "Extension.extension:attributeEstimate.extension:description.url",
        "path": "Extension.extension.extension.url",
        "min": 1,
        "max": "1",
        "base": {
          "path": "Extension.url",
          "min": 1,
          "max": "1"
        },
        "fixedUri": "description"
      },
      {
        "id": "Extension.extension:attributeEstimate.extension:description.value[x]",
        "path": "Extension.extension.extension.value[x]",
        "short": "Textual description of the attribute estimate",
        "definition": "Human-readable summary of the estimate.",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Extension.value[x]",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "markdown"
          }
        ]
      },
      {
        "id": "Extension.extension:attributeEstimate.extension:note",
        "path": "Extension.extension.extension",
        "sliceName": "note",
        "short": "R5: Footnote or explanatory note about the estimate (new)",
        "definition": "R5: `Evidence.statistic.attributeEstimate.note` (new:Annotation)",
        "comment": "Element `Evidence.statistic.attributeEstimate.note` is part of an existing definition because parent element `Evidence.statistic.attributeEstimate` requires a cross-version extension.\nElement `Evidence.statistic.attributeEstimate.note` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.attributeEstimate.note` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
        "requirements": "Element `Evidence.statistic.attributeEstimate.note` is part of an existing definition because parent element `Evidence.statistic.attributeEstimate` requires a cross-version extension.\nElement `Evidence.statistic.attributeEstimate.note` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.attributeEstimate.note` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
        "min": 0,
        "max": "*",
        "base": {
          "path": "Extension.extension",
          "min": 0,
          "max": "*"
        }
      },
      {
        "id": "Extension.extension:attributeEstimate.extension:note.url",
        "path": "Extension.extension.extension.url",
        "min": 1,
        "max": "1",
        "base": {
          "path": "Extension.url",
          "min": 1,
          "max": "1"
        },
        "fixedUri": "note"
      },
      {
        "id": "Extension.extension:attributeEstimate.extension:note.value[x]",
        "path": "Extension.extension.extension.value[x]",
        "short": "Footnote or explanatory note about the estimate",
        "definition": "Footnote or explanatory note about the estimate.",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Extension.value[x]",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "Annotation"
          }
        ]
      },
      {
        "id": "Extension.extension:attributeEstimate.extension:type",
        "path": "Extension.extension.extension",
        "sliceName": "type",
        "short": "R5: The type of attribute estimate, e.g., confidence interval or p value (new)",
        "definition": "R5: `Evidence.statistic.attributeEstimate.type` (new:CodeableConcept)",
        "comment": "Element `Evidence.statistic.attributeEstimate.type` is part of an existing definition because parent element `Evidence.statistic.attributeEstimate` requires a cross-version extension.\nElement `Evidence.statistic.attributeEstimate.type` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.attributeEstimate.type` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
        "requirements": "Element `Evidence.statistic.attributeEstimate.type` is part of an existing definition because parent element `Evidence.statistic.attributeEstimate` requires a cross-version extension.\nElement `Evidence.statistic.attributeEstimate.type` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.attributeEstimate.type` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Extension.extension",
          "min": 0,
          "max": "*"
        }
      },
      {
        "id": "Extension.extension:attributeEstimate.extension:type.url",
        "path": "Extension.extension.extension.url",
        "min": 1,
        "max": "1",
        "base": {
          "path": "Extension.url",
          "min": 1,
          "max": "1"
        },
        "fixedUri": "type"
      },
      {
        "id": "Extension.extension:attributeEstimate.extension:type.value[x]",
        "path": "Extension.extension.extension.value[x]",
        "short": "The type of attribute estimate, e.g., confidence interval or p value",
        "definition": "The type of attribute estimate, e.g., confidence interval or p value.",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Extension.value[x]",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "CodeableConcept"
          }
        ],
        "binding": {
          "strength": "extensible",
          "valueSet": "http://hl7.org/fhir/uv/xver/ValueSet/R5-attribute-estimate-type-for-R4|0.1.0"
        }
      },
      {
        "id": "Extension.extension:attributeEstimate.extension:quantity",
        "path": "Extension.extension.extension",
        "sliceName": "quantity",
        "short": "R5: The singular quantity of the attribute estimate, for attribute estimates represented as single values; also used to report unit of measure (new)",
        "definition": "R5: `Evidence.statistic.attributeEstimate.quantity` (new:Quantity)",
        "comment": "Element `Evidence.statistic.attributeEstimate.quantity` is part of an existing definition because parent element `Evidence.statistic.attributeEstimate` requires a cross-version extension.\nElement `Evidence.statistic.attributeEstimate.quantity` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.attributeEstimate.quantity` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).\nOften the p value",
        "requirements": "Element `Evidence.statistic.attributeEstimate.quantity` is part of an existing definition because parent element `Evidence.statistic.attributeEstimate` requires a cross-version extension.\nElement `Evidence.statistic.attributeEstimate.quantity` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.attributeEstimate.quantity` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Extension.extension",
          "min": 0,
          "max": "*"
        }
      },
      {
        "id": "Extension.extension:attributeEstimate.extension:quantity.url",
        "path": "Extension.extension.extension.url",
        "min": 1,
        "max": "1",
        "base": {
          "path": "Extension.url",
          "min": 1,
          "max": "1"
        },
        "fixedUri": "quantity"
      },
      {
        "id": "Extension.extension:attributeEstimate.extension:quantity.value[x]",
        "path": "Extension.extension.extension.value[x]",
        "short": "The singular quantity of the attribute estimate, for attribute estimates represented as single values; also used to report unit of measure",
        "definition": "The singular quantity of the attribute estimate, for attribute estimates represented as single values; also used to report unit of measure.",
        "comment": "Often the p value",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Extension.value[x]",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "Quantity"
          }
        ]
      },
      {
        "id": "Extension.extension:attributeEstimate.extension:level",
        "path": "Extension.extension.extension",
        "sliceName": "level",
        "short": "R5: Level of confidence interval, e.g., 0.95 for 95% confidence interval (new)",
        "definition": "R5: `Evidence.statistic.attributeEstimate.level` (new:decimal)",
        "comment": "Element `Evidence.statistic.attributeEstimate.level` is part of an existing definition because parent element `Evidence.statistic.attributeEstimate` requires a cross-version extension.\nElement `Evidence.statistic.attributeEstimate.level` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.attributeEstimate.level` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
        "requirements": "Element `Evidence.statistic.attributeEstimate.level` is part of an existing definition because parent element `Evidence.statistic.attributeEstimate` requires a cross-version extension.\nElement `Evidence.statistic.attributeEstimate.level` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.attributeEstimate.level` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Extension.extension",
          "min": 0,
          "max": "*"
        }
      },
      {
        "id": "Extension.extension:attributeEstimate.extension:level.url",
        "path": "Extension.extension.extension.url",
        "min": 1,
        "max": "1",
        "base": {
          "path": "Extension.url",
          "min": 1,
          "max": "1"
        },
        "fixedUri": "level"
      },
      {
        "id": "Extension.extension:attributeEstimate.extension:level.value[x]",
        "path": "Extension.extension.extension.value[x]",
        "short": "Level of confidence interval, e.g., 0.95 for 95% confidence interval",
        "definition": "Use 95 for a 95% confidence interval.",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Extension.value[x]",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "decimal"
          }
        ]
      },
      {
        "id": "Extension.extension:attributeEstimate.extension:range",
        "path": "Extension.extension.extension",
        "sliceName": "range",
        "short": "R5: Lower and upper bound values of the attribute estimate (new)",
        "definition": "R5: `Evidence.statistic.attributeEstimate.range` (new:Range)",
        "comment": "Element `Evidence.statistic.attributeEstimate.range` is part of an existing definition because parent element `Evidence.statistic.attributeEstimate` requires a cross-version extension.\nElement `Evidence.statistic.attributeEstimate.range` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.attributeEstimate.range` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
        "requirements": "Element `Evidence.statistic.attributeEstimate.range` is part of an existing definition because parent element `Evidence.statistic.attributeEstimate` requires a cross-version extension.\nElement `Evidence.statistic.attributeEstimate.range` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.attributeEstimate.range` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Extension.extension",
          "min": 0,
          "max": "*"
        }
      },
      {
        "id": "Extension.extension:attributeEstimate.extension:range.url",
        "path": "Extension.extension.extension.url",
        "min": 1,
        "max": "1",
        "base": {
          "path": "Extension.url",
          "min": 1,
          "max": "1"
        },
        "fixedUri": "range"
      },
      {
        "id": "Extension.extension:attributeEstimate.extension:range.value[x]",
        "path": "Extension.extension.extension.value[x]",
        "short": "Lower and upper bound values of the attribute estimate",
        "definition": "Lower bound of confidence interval.",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Extension.value[x]",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "Range"
          }
        ]
      },
      {
        "id": "Extension.extension:attributeEstimate.extension:attributeEstimate",
        "path": "Extension.extension.extension",
        "sliceName": "attributeEstimate",
        "short": "R5: A nested attribute estimate; which is the attribute estimate of an attribute estimate (new)",
        "definition": "R5: `Evidence.statistic.attributeEstimate.attributeEstimate` (new:Evidence.statistic.attributeEstimate)",
        "comment": "Element `Evidence.statistic.attributeEstimate.attributeEstimate` is part of an existing definition because parent element `Evidence.statistic.attributeEstimate` requires a cross-version extension.\nElement `Evidence.statistic.attributeEstimate.attributeEstimate` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.attributeEstimate.attributeEstimate` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).\nA nested attribute estimate; which is the attribute estimate of an attribute estimate",
        "requirements": "Element `Evidence.statistic.attributeEstimate.attributeEstimate` is part of an existing definition because parent element `Evidence.statistic.attributeEstimate` requires a cross-version extension.\nElement `Evidence.statistic.attributeEstimate.attributeEstimate` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.attributeEstimate.attributeEstimate` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
        "min": 0,
        "max": "*",
        "base": {
          "path": "Extension.extension",
          "min": 0,
          "max": "*"
        }
      },
      {
        "id": "Extension.extension:attributeEstimate.extension:attributeEstimate.url",
        "path": "Extension.extension.extension.url",
        "min": 1,
        "max": "1",
        "base": {
          "path": "Extension.url",
          "min": 1,
          "max": "1"
        },
        "fixedUri": "http://hl7.org/fhir/5.0/StructureDefinition/extension-Evidence.statistic.attributeEstimate"
      },
      {
        "id": "Extension.extension:attributeEstimate.extension:attributeEstimate.value[x]",
        "path": "Extension.extension.extension.value[x]",
        "min": 0,
        "max": "0",
        "base": {
          "path": "Extension.value[x]",
          "min": 0,
          "max": "1"
        }
      },
      {
        "id": "Extension.extension:attributeEstimate.url",
        "path": "Extension.extension.url",
        "min": 1,
        "max": "1",
        "base": {
          "path": "Extension.url",
          "min": 1,
          "max": "1"
        },
        "fixedUri": "attributeEstimate"
      },
      {
        "id": "Extension.extension:attributeEstimate.value[x]",
        "path": "Extension.extension.value[x]",
        "min": 0,
        "max": "0",
        "base": {
          "path": "Extension.value[x]",
          "min": 0,
          "max": "1"
        }
      },
      {
        "id": "Extension.extension:modelCharacteristic",
        "path": "Extension.extension",
        "sliceName": "modelCharacteristic",
        "short": "R5: An aspect of the statistical model (new)",
        "definition": "R5: `Evidence.statistic.modelCharacteristic` (new:BackboneElement)",
        "comment": "Element `Evidence.statistic.modelCharacteristic` is part of an existing definition because parent element `Evidence.statistic` requires a cross-version extension.\nElement `Evidence.statistic.modelCharacteristic` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.modelCharacteristic` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
        "requirements": "Element `Evidence.statistic.modelCharacteristic` is part of an existing definition because parent element `Evidence.statistic` requires a cross-version extension.\nElement `Evidence.statistic.modelCharacteristic` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.modelCharacteristic` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
        "min": 0,
        "max": "*",
        "base": {
          "path": "Extension.extension",
          "min": 0,
          "max": "*"
        }
      },
      {
        "id": "Extension.extension:modelCharacteristic.extension",
        "path": "Extension.extension.extension",
        "slicing": {
          "discriminator": [
            {
              "type": "value",
              "path": "url"
            }
          ],
          "ordered": false,
          "rules": "open"
        },
        "min": 1,
        "max": "*",
        "base": {
          "path": "Extension.extension",
          "min": 0,
          "max": "*"
        }
      },
      {
        "id": "Extension.extension:modelCharacteristic.extension:code",
        "path": "Extension.extension.extension",
        "sliceName": "code",
        "short": "R5: Model specification (new)",
        "definition": "R5: `Evidence.statistic.modelCharacteristic.code` (new:CodeableConcept)",
        "comment": "Element `Evidence.statistic.modelCharacteristic.code` is part of an existing definition because parent element `Evidence.statistic.modelCharacteristic` requires a cross-version extension.\nElement `Evidence.statistic.modelCharacteristic.code` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.modelCharacteristic.code` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
        "requirements": "Element `Evidence.statistic.modelCharacteristic.code` is part of an existing definition because parent element `Evidence.statistic.modelCharacteristic` requires a cross-version extension.\nElement `Evidence.statistic.modelCharacteristic.code` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.modelCharacteristic.code` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
        "min": 1,
        "max": "1",
        "base": {
          "path": "Extension.extension",
          "min": 0,
          "max": "*"
        }
      },
      {
        "id": "Extension.extension:modelCharacteristic.extension:code.url",
        "path": "Extension.extension.extension.url",
        "min": 1,
        "max": "1",
        "base": {
          "path": "Extension.url",
          "min": 1,
          "max": "1"
        },
        "fixedUri": "code"
      },
      {
        "id": "Extension.extension:modelCharacteristic.extension:code.value[x]",
        "path": "Extension.extension.extension.value[x]",
        "short": "Model specification",
        "definition": "Description of a component of the method to generate the statistic.",
        "min": 1,
        "max": "1",
        "base": {
          "path": "Extension.value[x]",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "CodeableConcept"
          }
        ],
        "binding": {
          "strength": "extensible",
          "valueSet": "http://hl7.org/fhir/uv/xver/ValueSet/R5-statistic-model-code-for-R4|0.1.0"
        }
      },
      {
        "id": "Extension.extension:modelCharacteristic.extension:value",
        "path": "Extension.extension.extension",
        "sliceName": "value",
        "short": "R5: Numerical value to complete model specification (new)",
        "definition": "R5: `Evidence.statistic.modelCharacteristic.value` (new:Quantity[SimpleQuantity])",
        "comment": "Element `Evidence.statistic.modelCharacteristic.value` is part of an existing definition because parent element `Evidence.statistic.modelCharacteristic` requires a cross-version extension.\nElement `Evidence.statistic.modelCharacteristic.value` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.modelCharacteristic.value` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
        "requirements": "Element `Evidence.statistic.modelCharacteristic.value` is part of an existing definition because parent element `Evidence.statistic.modelCharacteristic` requires a cross-version extension.\nElement `Evidence.statistic.modelCharacteristic.value` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.modelCharacteristic.value` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Extension.extension",
          "min": 0,
          "max": "*"
        }
      },
      {
        "id": "Extension.extension:modelCharacteristic.extension:value.url",
        "path": "Extension.extension.extension.url",
        "min": 1,
        "max": "1",
        "base": {
          "path": "Extension.url",
          "min": 1,
          "max": "1"
        },
        "fixedUri": "value"
      },
      {
        "id": "Extension.extension:modelCharacteristic.extension:value.value[x]",
        "path": "Extension.extension.extension.value[x]",
        "short": "Numerical value to complete model specification",
        "definition": "Further specification of the quantified value of the component of the method to generate the statistic.",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Extension.value[x]",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "Quantity",
            "profile": [
              "http://hl7.org/fhir/StructureDefinition/SimpleQuantity|4.0.1"
            ]
          }
        ]
      },
      {
        "id": "Extension.extension:modelCharacteristic.extension:variable",
        "path": "Extension.extension.extension",
        "sliceName": "variable",
        "short": "R5: A variable adjusted for in the adjusted analysis (new)",
        "definition": "R5: `Evidence.statistic.modelCharacteristic.variable` (new:BackboneElement)",
        "comment": "Element `Evidence.statistic.modelCharacteristic.variable` is part of an existing definition because parent element `Evidence.statistic.modelCharacteristic` requires a cross-version extension.\nElement `Evidence.statistic.modelCharacteristic.variable` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.modelCharacteristic.variable` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
        "requirements": "Element `Evidence.statistic.modelCharacteristic.variable` is part of an existing definition because parent element `Evidence.statistic.modelCharacteristic` requires a cross-version extension.\nElement `Evidence.statistic.modelCharacteristic.variable` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.modelCharacteristic.variable` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
        "min": 0,
        "max": "*",
        "base": {
          "path": "Extension.extension",
          "min": 0,
          "max": "*"
        }
      },
      {
        "id": "Extension.extension:modelCharacteristic.extension:variable.extension",
        "path": "Extension.extension.extension.extension",
        "slicing": {
          "discriminator": [
            {
              "type": "value",
              "path": "url"
            }
          ],
          "ordered": false,
          "rules": "open"
        },
        "min": 1,
        "max": "*",
        "base": {
          "path": "Extension.extension",
          "min": 0,
          "max": "*"
        }
      },
      {
        "id": "Extension.extension:modelCharacteristic.extension:variable.extension:variableDefinition",
        "path": "Extension.extension.extension.extension",
        "sliceName": "variableDefinition",
        "short": "R5: Description of the variable (new)",
        "definition": "R5: `Evidence.statistic.modelCharacteristic.variable.variableDefinition` (new:Reference(Group,EvidenceVariable))",
        "comment": "Element `Evidence.statistic.modelCharacteristic.variable.variableDefinition` is part of an existing definition because parent element `Evidence.statistic.modelCharacteristic.variable` requires a cross-version extension.\nElement `Evidence.statistic.modelCharacteristic.variable.variableDefinition` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.modelCharacteristic.variable.variableDefinition` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
        "requirements": "Element `Evidence.statistic.modelCharacteristic.variable.variableDefinition` is part of an existing definition because parent element `Evidence.statistic.modelCharacteristic.variable` requires a cross-version extension.\nElement `Evidence.statistic.modelCharacteristic.variable.variableDefinition` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.modelCharacteristic.variable.variableDefinition` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
        "min": 1,
        "max": "1",
        "base": {
          "path": "Extension.extension",
          "min": 0,
          "max": "*"
        }
      },
      {
        "id": "Extension.extension:modelCharacteristic.extension:variable.extension:variableDefinition.url",
        "path": "Extension.extension.extension.extension.url",
        "min": 1,
        "max": "1",
        "base": {
          "path": "Extension.url",
          "min": 1,
          "max": "1"
        },
        "fixedUri": "variableDefinition"
      },
      {
        "id": "Extension.extension:modelCharacteristic.extension:variable.extension:variableDefinition.value[x]",
        "path": "Extension.extension.extension.extension.value[x]",
        "short": "Description of the variable",
        "definition": "Description of the variable.",
        "min": 1,
        "max": "1",
        "base": {
          "path": "Extension.value[x]",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "Reference",
            "targetProfile": [
              "http://hl7.org/fhir/5.0/StructureDefinition/profile-Group|0.1.0",
              "http://hl7.org/fhir/StructureDefinition/Group|4.0.1",
              "http://hl7.org/fhir/5.0/StructureDefinition/profile-EvidenceVariable|0.1.0",
              "http://hl7.org/fhir/StructureDefinition/EvidenceVariable|4.0.1"
            ]
          }
        ]
      },
      {
        "id": "Extension.extension:modelCharacteristic.extension:variable.extension:handling",
        "path": "Extension.extension.extension.extension",
        "sliceName": "handling",
        "short": "R5: continuous | dichotomous | ordinal | polychotomous (new)",
        "definition": "R5: `Evidence.statistic.modelCharacteristic.variable.handling` (new:code)",
        "comment": "Element `Evidence.statistic.modelCharacteristic.variable.handling` is part of an existing definition because parent element `Evidence.statistic.modelCharacteristic.variable` requires a cross-version extension.\nElement `Evidence.statistic.modelCharacteristic.variable.handling` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.modelCharacteristic.variable.handling` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
        "requirements": "Element `Evidence.statistic.modelCharacteristic.variable.handling` is part of an existing definition because parent element `Evidence.statistic.modelCharacteristic.variable` requires a cross-version extension.\nElement `Evidence.statistic.modelCharacteristic.variable.handling` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.modelCharacteristic.variable.handling` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Extension.extension",
          "min": 0,
          "max": "*"
        }
      },
      {
        "id": "Extension.extension:modelCharacteristic.extension:variable.extension:handling.url",
        "path": "Extension.extension.extension.extension.url",
        "min": 1,
        "max": "1",
        "base": {
          "path": "Extension.url",
          "min": 1,
          "max": "1"
        },
        "fixedUri": "handling"
      },
      {
        "id": "Extension.extension:modelCharacteristic.extension:variable.extension:handling.value[x]",
        "path": "Extension.extension.extension.extension.value[x]",
        "short": "continuous | dichotomous | ordinal | polychotomous",
        "definition": "How the variable is classified for use in adjusted analysis.",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Extension.value[x]",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "code"
          }
        ],
        "binding": {
          "strength": "required",
          "valueSet": "http://hl7.org/fhir/uv/xver/ValueSet/R5-variable-handling-for-R4|0.1.0"
        }
      },
      {
        "id": "Extension.extension:modelCharacteristic.extension:variable.extension:valueCategory",
        "path": "Extension.extension.extension.extension",
        "sliceName": "valueCategory",
        "short": "R5: Description for grouping of ordinal or polychotomous variables (new)",
        "definition": "R5: `Evidence.statistic.modelCharacteristic.variable.valueCategory` (new:CodeableConcept)",
        "comment": "Element `Evidence.statistic.modelCharacteristic.variable.valueCategory` is part of an existing definition because parent element `Evidence.statistic.modelCharacteristic.variable` requires a cross-version extension.\nElement `Evidence.statistic.modelCharacteristic.variable.valueCategory` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.modelCharacteristic.variable.valueCategory` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
        "requirements": "Element `Evidence.statistic.modelCharacteristic.variable.valueCategory` is part of an existing definition because parent element `Evidence.statistic.modelCharacteristic.variable` requires a cross-version extension.\nElement `Evidence.statistic.modelCharacteristic.variable.valueCategory` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.modelCharacteristic.variable.valueCategory` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
        "min": 0,
        "max": "*",
        "base": {
          "path": "Extension.extension",
          "min": 0,
          "max": "*"
        }
      },
      {
        "id": "Extension.extension:modelCharacteristic.extension:variable.extension:valueCategory.url",
        "path": "Extension.extension.extension.extension.url",
        "min": 1,
        "max": "1",
        "base": {
          "path": "Extension.url",
          "min": 1,
          "max": "1"
        },
        "fixedUri": "valueCategory"
      },
      {
        "id": "Extension.extension:modelCharacteristic.extension:variable.extension:valueCategory.value[x]",
        "path": "Extension.extension.extension.extension.value[x]",
        "short": "Description for grouping of ordinal or polychotomous variables",
        "definition": "Description for grouping of ordinal or polychotomous variables.",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Extension.value[x]",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "CodeableConcept"
          }
        ]
      },
      {
        "id": "Extension.extension:modelCharacteristic.extension:variable.extension:valueQuantity",
        "path": "Extension.extension.extension.extension",
        "sliceName": "valueQuantity",
        "short": "R5: Discrete value for grouping of ordinal or polychotomous variables (new)",
        "definition": "R5: `Evidence.statistic.modelCharacteristic.variable.valueQuantity` (new:Quantity)",
        "comment": "Element `Evidence.statistic.modelCharacteristic.variable.valueQuantity` is part of an existing definition because parent element `Evidence.statistic.modelCharacteristic.variable` requires a cross-version extension.\nElement `Evidence.statistic.modelCharacteristic.variable.valueQuantity` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.modelCharacteristic.variable.valueQuantity` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
        "requirements": "Element `Evidence.statistic.modelCharacteristic.variable.valueQuantity` is part of an existing definition because parent element `Evidence.statistic.modelCharacteristic.variable` requires a cross-version extension.\nElement `Evidence.statistic.modelCharacteristic.variable.valueQuantity` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.modelCharacteristic.variable.valueQuantity` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
        "min": 0,
        "max": "*",
        "base": {
          "path": "Extension.extension",
          "min": 0,
          "max": "*"
        }
      },
      {
        "id": "Extension.extension:modelCharacteristic.extension:variable.extension:valueQuantity.url",
        "path": "Extension.extension.extension.extension.url",
        "min": 1,
        "max": "1",
        "base": {
          "path": "Extension.url",
          "min": 1,
          "max": "1"
        },
        "fixedUri": "valueQuantity"
      },
      {
        "id": "Extension.extension:modelCharacteristic.extension:variable.extension:valueQuantity.value[x]",
        "path": "Extension.extension.extension.extension.value[x]",
        "short": "Discrete value for grouping of ordinal or polychotomous variables",
        "definition": "Discrete value for grouping of ordinal or polychotomous variables.",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Extension.value[x]",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "Quantity"
          }
        ]
      },
      {
        "id": "Extension.extension:modelCharacteristic.extension:variable.extension:valueRange",
        "path": "Extension.extension.extension.extension",
        "sliceName": "valueRange",
        "short": "R5: Range of values for grouping of ordinal or polychotomous variables (new)",
        "definition": "R5: `Evidence.statistic.modelCharacteristic.variable.valueRange` (new:Range)",
        "comment": "Element `Evidence.statistic.modelCharacteristic.variable.valueRange` is part of an existing definition because parent element `Evidence.statistic.modelCharacteristic.variable` requires a cross-version extension.\nElement `Evidence.statistic.modelCharacteristic.variable.valueRange` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.modelCharacteristic.variable.valueRange` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
        "requirements": "Element `Evidence.statistic.modelCharacteristic.variable.valueRange` is part of an existing definition because parent element `Evidence.statistic.modelCharacteristic.variable` requires a cross-version extension.\nElement `Evidence.statistic.modelCharacteristic.variable.valueRange` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.modelCharacteristic.variable.valueRange` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
        "min": 0,
        "max": "*",
        "base": {
          "path": "Extension.extension",
          "min": 0,
          "max": "*"
        }
      },
      {
        "id": "Extension.extension:modelCharacteristic.extension:variable.extension:valueRange.url",
        "path": "Extension.extension.extension.extension.url",
        "min": 1,
        "max": "1",
        "base": {
          "path": "Extension.url",
          "min": 1,
          "max": "1"
        },
        "fixedUri": "valueRange"
      },
      {
        "id": "Extension.extension:modelCharacteristic.extension:variable.extension:valueRange.value[x]",
        "path": "Extension.extension.extension.extension.value[x]",
        "short": "Range of values for grouping of ordinal or polychotomous variables",
        "definition": "Range of values for grouping of ordinal or polychotomous variables.",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Extension.value[x]",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "Range"
          }
        ]
      },
      {
        "id": "Extension.extension:modelCharacteristic.extension:variable.url",
        "path": "Extension.extension.extension.url",
        "min": 1,
        "max": "1",
        "base": {
          "path": "Extension.url",
          "min": 1,
          "max": "1"
        },
        "fixedUri": "variable"
      },
      {
        "id": "Extension.extension:modelCharacteristic.extension:variable.value[x]",
        "path": "Extension.extension.extension.value[x]",
        "min": 0,
        "max": "0",
        "base": {
          "path": "Extension.value[x]",
          "min": 0,
          "max": "1"
        }
      },
      {
        "id": "Extension.extension:modelCharacteristic.extension:attributeEstimate",
        "path": "Extension.extension.extension",
        "sliceName": "attributeEstimate",
        "short": "R5: An attribute of the statistic used as a model characteristic (new)",
        "definition": "R5: `Evidence.statistic.modelCharacteristic.attributeEstimate` (new:Evidence.statistic.attributeEstimate)",
        "comment": "Element `Evidence.statistic.modelCharacteristic.attributeEstimate` is part of an existing definition because parent element `Evidence.statistic.modelCharacteristic` requires a cross-version extension.\nElement `Evidence.statistic.modelCharacteristic.attributeEstimate` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.modelCharacteristic.attributeEstimate` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
        "requirements": "Element `Evidence.statistic.modelCharacteristic.attributeEstimate` is part of an existing definition because parent element `Evidence.statistic.modelCharacteristic` requires a cross-version extension.\nElement `Evidence.statistic.modelCharacteristic.attributeEstimate` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.modelCharacteristic.attributeEstimate` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
        "min": 0,
        "max": "*",
        "base": {
          "path": "Extension.extension",
          "min": 0,
          "max": "*"
        }
      },
      {
        "id": "Extension.extension:modelCharacteristic.extension:attributeEstimate.url",
        "path": "Extension.extension.extension.url",
        "min": 1,
        "max": "1",
        "base": {
          "path": "Extension.url",
          "min": 1,
          "max": "1"
        },
        "fixedUri": "http://hl7.org/fhir/5.0/StructureDefinition/extension-Evidence.statistic.attributeEstimate"
      },
      {
        "id": "Extension.extension:modelCharacteristic.extension:attributeEstimate.value[x]",
        "path": "Extension.extension.extension.value[x]",
        "min": 0,
        "max": "0",
        "base": {
          "path": "Extension.value[x]",
          "min": 0,
          "max": "1"
        }
      },
      {
        "id": "Extension.extension:modelCharacteristic.url",
        "path": "Extension.extension.url",
        "min": 1,
        "max": "1",
        "base": {
          "path": "Extension.url",
          "min": 1,
          "max": "1"
        },
        "fixedUri": "modelCharacteristic"
      },
      {
        "id": "Extension.extension:modelCharacteristic.value[x]",
        "path": "Extension.extension.value[x]",
        "min": 0,
        "max": "0",
        "base": {
          "path": "Extension.value[x]",
          "min": 0,
          "max": "1"
        }
      },
      {
        "id": "Extension.url",
        "path": "Extension.url",
        "min": 1,
        "max": "1",
        "base": {
          "path": "Extension.url",
          "min": 1,
          "max": "1"
        },
        "fixedUri": "http://hl7.org/fhir/5.0/StructureDefinition/extension-Evidence.statistic"
      },
      {
        "id": "Extension.value[x]",
        "path": "Extension.value[x]",
        "min": 0,
        "max": "0",
        "base": {
          "path": "Extension.value[x]",
          "min": 0,
          "max": "1"
        }
      }
    ]
  }
}