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Packagehl7.fhir.uv.xver-r4b.r5
Resource TypeStructureDefinition
IdStructureDefinition-ext-R4B-MedicationKnowledge.ingredient.json
FHIR VersionR5
Sourcehttp://hl7.org/fhir/uv/xver-r4b.r5/0.1.0/StructureDefinition-ext-R4B-MedicationKnowledge.ingredient.html
URLhttp://hl7.org/fhir/4.3/StructureDefinition/extension-MedicationKnowledge.ingredient
Version0.1.0
Statusactive
Date2026-03-17T21:02:03.8104715+00:00
NameExtensionMedicationKnowledge_Ingredient
TitleR4B: Active or inactive ingredient (new)
Realmuv
Authorityhl7
DescriptionR4B: `MedicationKnowledge.ingredient` (new:BackboneElement)
PurposeThis extension is part of the cross-version definitions generated to enable use of the element `MedicationKnowledge.ingredient` as defined in FHIR R4B in FHIR R5. The source element is defined as: `MedicationKnowledge.ingredient` 0..* `BackboneElement` Following are the generation technical comments: Element `MedicationKnowledge.ingredient` has a context of MedicationKnowledge based on following the parent source element upwards and mapping to `MedicationKnowledge`. Element `MedicationKnowledge.ingredient` has no mapping targets in FHIR R5. Typically, this is because the element has been added (is a new element).
TypeExtension
Kindcomplex-type

Resources that use this resource

ConceptMap
hl7.fhir.uv.xver-r4b.r5#0.1.0R4B-MedicationKnowledge-element-map-to-R5Cross-version mapping for FHIR R4B MedicationKnowledge to FHIR R5 MedicationKnowledge
hl7.fhir.uv.xver-r4b.r3#0.1.0R4B-MedicationKnowledge-element-map-to-R3Cross-version mapping for FHIR R4B MedicationKnowledge to FHIR STU3 Basic
StructureDefinition
hl7.fhir.uv.xver-r4b.r5#0.1.0profile-MedicationKnowledgeCross-version Profile for R4B.MedicationKnowledge for use in FHIR R5

Resources that this resource uses

StructureDefinition
hl7.fhir.uv.xver-r4b.r5#0.1.0profile-SubstanceCross-version Profile for R4B.Substance for use in FHIR R5

Examples of Use for Extension

No extension usage examples found


Narrative

Note: links and images are rebased to the (stated) source

Generated Narrative: StructureDefinition ext-R4B-MedicationKnowledge.ingredient

NameFlagsCard.TypeDescription & Constraintsdoco
.. Extension 0..*Extension(5.0.0)R4B: Active or inactive ingredient (new)
... Slices for extension 1..*ExtensionExtension
Slice: Unordered, Open by value:url
.... extension:item 1..1ExtensionR4B: Medication(s) or substance(s) contained in the medication (new)
..... url 1..1uri"item"
..... value[x] 1..1Medication(s) or substance(s) contained in the medication
...... valueCodeableConceptCodeableConcept
...... valueReferenceReference(Cross-version Profile for R4B.Substance for use in FHIR R5(0.1.0) | Substance)
.... extension:isActive 0..1ExtensionR4B: Active ingredient indicator (new)
..... url 1..1uri"isActive"
..... value[x] 0..1booleanActive ingredient indicator
.... extension:strength 0..1ExtensionR4B: Quantity of ingredient present (new)
..... url 1..1uri"strength"
..... value[x] 0..1RatioQuantity of ingredient present
... url 1..1uri"http://hl7.org/fhir/4.3/StructureDefinition/extension-MedicationKnowledge.ingredient"
... value[x] 0..0Value of extension

doco Documentation for this format

Source1

{
  "resourceType": "StructureDefinition",
  "id": "ext-R4B-MedicationKnowledge.ingredient",
  "text": {
    "status": "extensions",
    "div": "<!-- snip (see above) -->"
  },
  "extension": [
    {
      "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-wg",
      "valueCode": "fhir"
    },
    {
      "extension": [
        {
          "url": "packageId",
          "valueId": "hl7.fhir.uv.xver-r4b.r5"
        },
        {
          "url": "version",
          "valueString": "0.1.0"
        },
        {
          "url": "uri",
          "valueUri": "http://hl7.org/fhir/uv/xver/ImplementationGuide/hl7.fhir.uv.xver-r4b.r5"
        }
      ],
      "url": "http://hl7.org/fhir/StructureDefinition/package-source"
    },
    {
      "extension": [
        {
          "url": "startFhirVersion",
          "valueCode": "5.0"
        },
        {
          "url": "endFhirVersion",
          "valueCode": "5.0"
        }
      ],
      "url": "http://hl7.org/fhir/StructureDefinition/version-specific-use"
    },
    {
      "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-type-characteristics",
      "valueCode": "can-bind"
    },
    {
      "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fmm",
      "valueInteger": 0,
      "_valueInteger": {
        "extension": [
          {
            "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-conformance-derivedFrom",
            "valueCanonical": "http://hl7.org/fhir/uv/xver/ImplementationGuide/hl7.fhir.uv.xver-r4b.r5"
          }
        ]
      }
    },
    {
      "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status",
      "valueCode": "trial-use",
      "_valueCode": {
        "extension": [
          {
            "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-conformance-derivedFrom",
            "valueCanonical": "http://hl7.org/fhir/uv/xver/ImplementationGuide/hl7.fhir.uv.xver-r4b.r5"
          }
        ]
      }
    }
  ],
  "url": "http://hl7.org/fhir/4.3/StructureDefinition/extension-MedicationKnowledge.ingredient",
  "version": "0.1.0",
  "name": "ExtensionMedicationKnowledge_Ingredient",
  "title": "R4B: Active or inactive ingredient (new)",
  "status": "active",
  "experimental": false,
  "date": "2026-03-17T21:02:03.8104715+00:00",
  "publisher": "FHIR Infrastructure",
  "contact": [
    {
      "name": "FHIR Infrastructure",
      "telecom": [
        {
          "system": "url",
          "value": "http://www.hl7.org/Special/committees/fiwg"
        }
      ]
    }
  ],
  "description": "R4B: `MedicationKnowledge.ingredient` (new:BackboneElement)",
  "jurisdiction": [
    {
      "coding": [
        {
          "system": "http://unstats.un.org/unsd/methods/m49/m49.htm",
          "code": "001",
          "display": "World"
        }
      ]
    }
  ],
  "purpose": "This extension is part of the cross-version definitions generated to enable use of the\r\nelement `MedicationKnowledge.ingredient` as defined in FHIR R4B\r\nin FHIR R5.\r\n\r\nThe source element is defined as:\r\n`MedicationKnowledge.ingredient` 0..* `BackboneElement`\r\n\r\nFollowing are the generation technical comments:\r\nElement `MedicationKnowledge.ingredient` has a context of MedicationKnowledge based on following the parent source element upwards and mapping to `MedicationKnowledge`.\nElement `MedicationKnowledge.ingredient` has no mapping targets in FHIR R5. Typically, this is because the element has been added (is a new element).",
  "fhirVersion": "5.0.0",
  "mapping": [
    {
      "identity": "rim",
      "uri": "http://hl7.org/v3",
      "name": "RIM Mapping"
    }
  ],
  "kind": "complex-type",
  "abstract": false,
  "context": [
    {
      "type": "element",
      "expression": "MedicationKnowledge"
    }
  ],
  "type": "Extension",
  "baseDefinition": "http://hl7.org/fhir/StructureDefinition/Extension|5.0.0",
  "derivation": "constraint",
  "snapshot": {
    "extension": [
      {
        "url": "http://hl7.org/fhir/tools/StructureDefinition/snapshot-base-version",
        "valueString": "5.0.0"
      }
    ],
    "element": [
      {
        "id": "Extension",
        "path": "Extension",
        "short": "R4B: Active or inactive ingredient (new)",
        "definition": "R4B: `MedicationKnowledge.ingredient` (new:BackboneElement)",
        "comment": "Element `MedicationKnowledge.ingredient` has a context of MedicationKnowledge based on following the parent source element upwards and mapping to `MedicationKnowledge`.\nElement `MedicationKnowledge.ingredient` has no mapping targets in FHIR R5. Typically, this is because the element has been added (is a new element).",
        "min": 0,
        "max": "*",
        "base": {
          "path": "Extension",
          "min": 0,
          "max": "*"
        },
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "source": "http://hl7.org/fhir/StructureDefinition/Element|5.0.0"
          },
          {
            "key": "ext-1",
            "severity": "error",
            "human": "Must have either extensions or value[x], not both",
            "expression": "extension.exists() != value.exists()",
            "source": "http://hl7.org/fhir/StructureDefinition/Extension|5.0.0"
          }
        ],
        "isModifier": false
      },
      {
        "id": "Extension.id",
        "path": "Extension.id",
        "representation": [
          "xmlAttr"
        ],
        "short": "Unique id for inter-element referencing",
        "definition": "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Element.id",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
                "valueUrl": "id"
              }
            ],
            "code": "http://hl7.org/fhirpath/System.String"
          }
        ],
        "condition": [
          "ele-1"
        ],
        "isModifier": false,
        "isSummary": false,
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          }
        ]
      },
      {
        "id": "Extension.extension",
        "path": "Extension.extension",
        "slicing": {
          "discriminator": [
            {
              "type": "value",
              "path": "url"
            }
          ],
          "description": "Extensions are always sliced by (at least) url",
          "ordered": false,
          "rules": "open"
        },
        "short": "Extension",
        "definition": "An Extension",
        "min": 1,
        "max": "*",
        "base": {
          "path": "Element.extension",
          "min": 0,
          "max": "*"
        },
        "type": [
          {
            "code": "Extension"
          }
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "source": "http://hl7.org/fhir/StructureDefinition/Element|5.0.0"
          },
          {
            "key": "ext-1",
            "severity": "error",
            "human": "Must have either extensions or value[x], not both",
            "expression": "extension.exists() != value.exists()",
            "source": "http://hl7.org/fhir/StructureDefinition/Extension|5.0.0"
          }
        ],
        "isModifier": false,
        "isSummary": false
      },
      {
        "id": "Extension.extension:item",
        "path": "Extension.extension",
        "sliceName": "item",
        "short": "R4B: Medication(s) or substance(s) contained in the medication (new)",
        "definition": "R4B: `MedicationKnowledge.ingredient.item[x]` (new:CodeableConcept, Reference(Substance))",
        "comment": "Element `MedicationKnowledge.ingredient.item[x]` is part of an existing definition because parent element `MedicationKnowledge.ingredient` requires a cross-version extension.\nElement `MedicationKnowledge.ingredient.item[x]` has a context of MedicationKnowledge based on following the parent source element upwards and mapping to `MedicationKnowledge`.\nElement `MedicationKnowledge.ingredient.item[x]` has no mapping targets in FHIR R5. Typically, this is because the element has been added (is a new element).",
        "requirements": "Element `MedicationKnowledge.ingredient.item[x]` is part of an existing definition because parent element `MedicationKnowledge.ingredient` requires a cross-version extension.\nElement `MedicationKnowledge.ingredient.item[x]` has a context of MedicationKnowledge based on following the parent source element upwards and mapping to `MedicationKnowledge`.\nElement `MedicationKnowledge.ingredient.item[x]` has no mapping targets in FHIR R5. Typically, this is because the element has been added (is a new element).",
        "min": 1,
        "max": "1",
        "base": {
          "path": "Element.extension",
          "min": 0,
          "max": "*"
        },
        "type": [
          {
            "code": "Extension"
          }
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "source": "http://hl7.org/fhir/StructureDefinition/Element|5.0.0"
          },
          {
            "key": "ext-1",
            "severity": "error",
            "human": "Must have either extensions or value[x], not both",
            "expression": "extension.exists() != value.exists()",
            "source": "http://hl7.org/fhir/StructureDefinition/Extension|5.0.0"
          }
        ],
        "isModifier": false,
        "isSummary": false
      },
      {
        "id": "Extension.extension:item.id",
        "path": "Extension.extension.id",
        "representation": [
          "xmlAttr"
        ],
        "short": "Unique id for inter-element referencing",
        "definition": "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Element.id",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
                "valueUrl": "id"
              }
            ],
            "code": "http://hl7.org/fhirpath/System.String"
          }
        ],
        "condition": [
          "ele-1"
        ],
        "isModifier": false,
        "isSummary": false,
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          }
        ]
      },
      {
        "id": "Extension.extension:item.extension",
        "path": "Extension.extension.extension",
        "slicing": {
          "discriminator": [
            {
              "type": "value",
              "path": "url"
            }
          ],
          "description": "Extensions are always sliced by (at least) url",
          "rules": "open"
        },
        "short": "Additional content defined by implementations",
        "definition": "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.",
        "comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
        "alias": [
          "extensions",
          "user content"
        ],
        "min": 0,
        "max": "*",
        "base": {
          "path": "Element.extension",
          "min": 0,
          "max": "*"
        },
        "type": [
          {
            "code": "Extension"
          }
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "source": "http://hl7.org/fhir/StructureDefinition/Element|5.0.0"
          },
          {
            "key": "ext-1",
            "severity": "error",
            "human": "Must have either extensions or value[x], not both",
            "expression": "extension.exists() != value.exists()",
            "source": "http://hl7.org/fhir/StructureDefinition/Extension|5.0.0"
          }
        ],
        "isModifier": false,
        "isSummary": false,
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          }
        ]
      },
      {
        "id": "Extension.extension:item.url",
        "path": "Extension.extension.url",
        "representation": [
          "xmlAttr"
        ],
        "short": "identifies the meaning of the extension",
        "definition": "Source of the definition for the extension code - a logical name or a URL.",
        "comment": "The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.",
        "min": 1,
        "max": "1",
        "base": {
          "path": "Extension.url",
          "min": 1,
          "max": "1"
        },
        "type": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
                "valueUrl": "uri"
              }
            ],
            "code": "http://hl7.org/fhirpath/System.String"
          }
        ],
        "fixedUri": "item",
        "isModifier": false,
        "isSummary": false,
        "mapping": [
          {
            "identity": "rim",
            "map": "N/A"
          }
        ]
      },
      {
        "id": "Extension.extension:item.value[x]",
        "path": "Extension.extension.value[x]",
        "short": "Medication(s) or substance(s) contained in the medication",
        "definition": "The actual ingredient - either a substance (simple ingredient) or another medication.",
        "min": 1,
        "max": "1",
        "base": {
          "path": "Extension.value[x]",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "CodeableConcept"
          },
          {
            "code": "Reference",
            "targetProfile": [
              "http://hl7.org/fhir/4.3/StructureDefinition/profile-Substance|0.1.0",
              "http://hl7.org/fhir/StructureDefinition/Substance|5.0.0"
            ]
          }
        ],
        "condition": [
          "ext-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "source": "http://hl7.org/fhir/StructureDefinition/Element|5.0.0"
          }
        ],
        "isModifier": false,
        "isSummary": false,
        "mapping": [
          {
            "identity": "rim",
            "map": "N/A"
          }
        ]
      },
      {
        "id": "Extension.extension:isActive",
        "path": "Extension.extension",
        "sliceName": "isActive",
        "short": "R4B: Active ingredient indicator (new)",
        "definition": "R4B: `MedicationKnowledge.ingredient.isActive` (new:boolean)",
        "comment": "Element `MedicationKnowledge.ingredient.isActive` is part of an existing definition because parent element `MedicationKnowledge.ingredient` requires a cross-version extension.\nElement `MedicationKnowledge.ingredient.isActive` has a context of MedicationKnowledge based on following the parent source element upwards and mapping to `MedicationKnowledge`.\nElement `MedicationKnowledge.ingredient.isActive` has no mapping targets in FHIR R5. Typically, this is because the element has been added (is a new element).",
        "requirements": "True indicates that the ingredient affects the therapeutic action of the drug (i.e. active). \rFalse indicates that the ingredient does not affect the therapeutic action of the drug (i.e. inactive). Element `MedicationKnowledge.ingredient.isActive` is part of an existing definition because parent element `MedicationKnowledge.ingredient` requires a cross-version extension.\nElement `MedicationKnowledge.ingredient.isActive` has a context of MedicationKnowledge based on following the parent source element upwards and mapping to `MedicationKnowledge`.\nElement `MedicationKnowledge.ingredient.isActive` has no mapping targets in FHIR R5. Typically, this is because the element has been added (is a new element).",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Element.extension",
          "min": 0,
          "max": "*"
        },
        "type": [
          {
            "code": "Extension"
          }
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "source": "http://hl7.org/fhir/StructureDefinition/Element|5.0.0"
          },
          {
            "key": "ext-1",
            "severity": "error",
            "human": "Must have either extensions or value[x], not both",
            "expression": "extension.exists() != value.exists()",
            "source": "http://hl7.org/fhir/StructureDefinition/Extension|5.0.0"
          }
        ],
        "isModifier": false,
        "isSummary": false
      },
      {
        "id": "Extension.extension:isActive.id",
        "path": "Extension.extension.id",
        "representation": [
          "xmlAttr"
        ],
        "short": "Unique id for inter-element referencing",
        "definition": "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Element.id",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
                "valueUrl": "id"
              }
            ],
            "code": "http://hl7.org/fhirpath/System.String"
          }
        ],
        "condition": [
          "ele-1"
        ],
        "isModifier": false,
        "isSummary": false,
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          }
        ]
      },
      {
        "id": "Extension.extension:isActive.extension",
        "path": "Extension.extension.extension",
        "slicing": {
          "discriminator": [
            {
              "type": "value",
              "path": "url"
            }
          ],
          "description": "Extensions are always sliced by (at least) url",
          "rules": "open"
        },
        "short": "Additional content defined by implementations",
        "definition": "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.",
        "comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
        "alias": [
          "extensions",
          "user content"
        ],
        "min": 0,
        "max": "*",
        "base": {
          "path": "Element.extension",
          "min": 0,
          "max": "*"
        },
        "type": [
          {
            "code": "Extension"
          }
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "source": "http://hl7.org/fhir/StructureDefinition/Element|5.0.0"
          },
          {
            "key": "ext-1",
            "severity": "error",
            "human": "Must have either extensions or value[x], not both",
            "expression": "extension.exists() != value.exists()",
            "source": "http://hl7.org/fhir/StructureDefinition/Extension|5.0.0"
          }
        ],
        "isModifier": false,
        "isSummary": false,
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          }
        ]
      },
      {
        "id": "Extension.extension:isActive.url",
        "path": "Extension.extension.url",
        "representation": [
          "xmlAttr"
        ],
        "short": "identifies the meaning of the extension",
        "definition": "Source of the definition for the extension code - a logical name or a URL.",
        "comment": "The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.",
        "min": 1,
        "max": "1",
        "base": {
          "path": "Extension.url",
          "min": 1,
          "max": "1"
        },
        "type": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
                "valueUrl": "uri"
              }
            ],
            "code": "http://hl7.org/fhirpath/System.String"
          }
        ],
        "fixedUri": "isActive",
        "isModifier": false,
        "isSummary": false,
        "mapping": [
          {
            "identity": "rim",
            "map": "N/A"
          }
        ]
      },
      {
        "id": "Extension.extension:isActive.value[x]",
        "path": "Extension.extension.value[x]",
        "short": "Active ingredient indicator",
        "definition": "Indication of whether this ingredient affects the therapeutic action of the drug.",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Extension.value[x]",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "boolean"
          }
        ],
        "condition": [
          "ext-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "source": "http://hl7.org/fhir/StructureDefinition/Element|5.0.0"
          }
        ],
        "isModifier": false,
        "isSummary": false,
        "mapping": [
          {
            "identity": "rim",
            "map": "N/A"
          }
        ]
      },
      {
        "id": "Extension.extension:strength",
        "path": "Extension.extension",
        "sliceName": "strength",
        "short": "R4B: Quantity of ingredient present (new)",
        "definition": "R4B: `MedicationKnowledge.ingredient.strength` (new:Ratio)",
        "comment": "Element `MedicationKnowledge.ingredient.strength` is part of an existing definition because parent element `MedicationKnowledge.ingredient` requires a cross-version extension.\nElement `MedicationKnowledge.ingredient.strength` has a context of MedicationKnowledge based on following the parent source element upwards and mapping to `MedicationKnowledge`.\nElement `MedicationKnowledge.ingredient.strength` has no mapping targets in FHIR R5. Typically, this is because the element has been added (is a new element).",
        "requirements": "Element `MedicationKnowledge.ingredient.strength` is part of an existing definition because parent element `MedicationKnowledge.ingredient` requires a cross-version extension.\nElement `MedicationKnowledge.ingredient.strength` has a context of MedicationKnowledge based on following the parent source element upwards and mapping to `MedicationKnowledge`.\nElement `MedicationKnowledge.ingredient.strength` has no mapping targets in FHIR R5. Typically, this is because the element has been added (is a new element).",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Element.extension",
          "min": 0,
          "max": "*"
        },
        "type": [
          {
            "code": "Extension"
          }
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "source": "http://hl7.org/fhir/StructureDefinition/Element|5.0.0"
          },
          {
            "key": "ext-1",
            "severity": "error",
            "human": "Must have either extensions or value[x], not both",
            "expression": "extension.exists() != value.exists()",
            "source": "http://hl7.org/fhir/StructureDefinition/Extension|5.0.0"
          }
        ],
        "isModifier": false,
        "isSummary": false
      },
      {
        "id": "Extension.extension:strength.id",
        "path": "Extension.extension.id",
        "representation": [
          "xmlAttr"
        ],
        "short": "Unique id for inter-element referencing",
        "definition": "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Element.id",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
                "valueUrl": "id"
              }
            ],
            "code": "http://hl7.org/fhirpath/System.String"
          }
        ],
        "condition": [
          "ele-1"
        ],
        "isModifier": false,
        "isSummary": false,
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          }
        ]
      },
      {
        "id": "Extension.extension:strength.extension",
        "path": "Extension.extension.extension",
        "slicing": {
          "discriminator": [
            {
              "type": "value",
              "path": "url"
            }
          ],
          "description": "Extensions are always sliced by (at least) url",
          "rules": "open"
        },
        "short": "Additional content defined by implementations",
        "definition": "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.",
        "comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
        "alias": [
          "extensions",
          "user content"
        ],
        "min": 0,
        "max": "*",
        "base": {
          "path": "Element.extension",
          "min": 0,
          "max": "*"
        },
        "type": [
          {
            "code": "Extension"
          }
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "source": "http://hl7.org/fhir/StructureDefinition/Element|5.0.0"
          },
          {
            "key": "ext-1",
            "severity": "error",
            "human": "Must have either extensions or value[x], not both",
            "expression": "extension.exists() != value.exists()",
            "source": "http://hl7.org/fhir/StructureDefinition/Extension|5.0.0"
          }
        ],
        "isModifier": false,
        "isSummary": false,
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          }
        ]
      },
      {
        "id": "Extension.extension:strength.url",
        "path": "Extension.extension.url",
        "representation": [
          "xmlAttr"
        ],
        "short": "identifies the meaning of the extension",
        "definition": "Source of the definition for the extension code - a logical name or a URL.",
        "comment": "The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.",
        "min": 1,
        "max": "1",
        "base": {
          "path": "Extension.url",
          "min": 1,
          "max": "1"
        },
        "type": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
                "valueUrl": "uri"
              }
            ],
            "code": "http://hl7.org/fhirpath/System.String"
          }
        ],
        "fixedUri": "strength",
        "isModifier": false,
        "isSummary": false,
        "mapping": [
          {
            "identity": "rim",
            "map": "N/A"
          }
        ]
      },
      {
        "id": "Extension.extension:strength.value[x]",
        "path": "Extension.extension.value[x]",
        "short": "Quantity of ingredient present",
        "definition": "Specifies how many (or how much) of the items there are in this Medication.  For example, 250 mg per tablet.  This is expressed as a ratio where the numerator is 250mg and the denominator is 1 tablet.",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Extension.value[x]",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "Ratio"
          }
        ],
        "condition": [
          "ext-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "source": "http://hl7.org/fhir/StructureDefinition/Element|5.0.0"
          }
        ],
        "isModifier": false,
        "isSummary": false,
        "mapping": [
          {
            "identity": "rim",
            "map": "N/A"
          }
        ]
      },
      {
        "id": "Extension.url",
        "path": "Extension.url",
        "representation": [
          "xmlAttr"
        ],
        "short": "identifies the meaning of the extension",
        "definition": "Source of the definition for the extension code - a logical name or a URL.",
        "comment": "The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.",
        "min": 1,
        "max": "1",
        "base": {
          "path": "Extension.url",
          "min": 1,
          "max": "1"
        },
        "type": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
                "valueUrl": "uri"
              }
            ],
            "code": "http://hl7.org/fhirpath/System.String"
          }
        ],
        "fixedUri": "http://hl7.org/fhir/4.3/StructureDefinition/extension-MedicationKnowledge.ingredient",
        "isModifier": false,
        "isSummary": false,
        "mapping": [
          {
            "identity": "rim",
            "map": "N/A"
          }
        ]
      },
      {
        "id": "Extension.value[x]",
        "path": "Extension.value[x]",
        "short": "Value of extension",
        "definition": "Value of extension - must be one of a constrained set of the data types (see [Extensibility](http://hl7.org/fhir/R5/extensibility.html) for a list).",
        "min": 0,
        "max": "0",
        "base": {
          "path": "Extension.value[x]",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "base64Binary"
          },
          {
            "code": "boolean"
          },
          {
            "code": "canonical"
          },
          {
            "code": "code"
          },
          {
            "code": "date"
          },
          {
            "code": "dateTime"
          },
          {
            "code": "decimal"
          },
          {
            "code": "id"
          },
          {
            "code": "instant"
          },
          {
            "code": "integer"
          },
          {
            "code": "integer64"
          },
          {
            "code": "markdown"
          },
          {
            "code": "oid"
          },
          {
            "code": "positiveInt"
          },
          {
            "code": "string"
          },
          {
            "code": "time"
          },
          {
            "code": "unsignedInt"
          },
          {
            "code": "uri"
          },
          {
            "code": "url"
          },
          {
            "code": "uuid"
          },
          {
            "code": "Address"
          },
          {
            "code": "Age"
          },
          {
            "code": "Annotation"
          },
          {
            "code": "Attachment"
          },
          {
            "code": "CodeableConcept"
          },
          {
            "code": "CodeableReference"
          },
          {
            "code": "Coding"
          },
          {
            "code": "ContactPoint"
          },
          {
            "code": "Count"
          },
          {
            "code": "Distance"
          },
          {
            "code": "Duration"
          },
          {
            "code": "HumanName"
          },
          {
            "code": "Identifier"
          },
          {
            "code": "Money"
          },
          {
            "code": "Period"
          },
          {
            "code": "Quantity"
          },
          {
            "code": "Range"
          },
          {
            "code": "Ratio"
          },
          {
            "code": "RatioRange"
          },
          {
            "code": "Reference"
          },
          {
            "code": "SampledData"
          },
          {
            "code": "Signature"
          },
          {
            "code": "Timing"
          },
          {
            "code": "ContactDetail"
          },
          {
            "code": "DataRequirement"
          },
          {
            "code": "Expression"
          },
          {
            "code": "ParameterDefinition"
          },
          {
            "code": "RelatedArtifact"
          },
          {
            "code": "TriggerDefinition"
          },
          {
            "code": "UsageContext"
          },
          {
            "code": "Availability"
          },
          {
            "code": "ExtendedContactDetail"
          },
          {
            "code": "Dosage"
          },
          {
            "code": "Meta"
          }
        ],
        "condition": [
          "ext-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "source": "http://hl7.org/fhir/StructureDefinition/Element|5.0.0"
          }
        ],
        "isModifier": false,
        "isSummary": false,
        "mapping": [
          {
            "identity": "rim",
            "map": "N/A"
          }
        ]
      }
    ]
  },
  "differential": {
    "element": [
      {
        "id": "Extension",
        "path": "Extension",
        "short": "R4B: Active or inactive ingredient (new)",
        "definition": "R4B: `MedicationKnowledge.ingredient` (new:BackboneElement)",
        "comment": "Element `MedicationKnowledge.ingredient` has a context of MedicationKnowledge based on following the parent source element upwards and mapping to `MedicationKnowledge`.\nElement `MedicationKnowledge.ingredient` has no mapping targets in FHIR R5. Typically, this is because the element has been added (is a new element).",
        "min": 0,
        "max": "*",
        "base": {
          "path": "Extension",
          "min": 0,
          "max": "*"
        },
        "isModifier": false
      },
      {
        "id": "Extension.extension",
        "path": "Extension.extension",
        "slicing": {
          "discriminator": [
            {
              "type": "value",
              "path": "url"
            }
          ],
          "ordered": false,
          "rules": "open"
        },
        "min": 1,
        "max": "*",
        "base": {
          "path": "Extension.extension",
          "min": 0,
          "max": "*"
        }
      },
      {
        "id": "Extension.extension:item",
        "path": "Extension.extension",
        "sliceName": "item",
        "short": "R4B: Medication(s) or substance(s) contained in the medication (new)",
        "definition": "R4B: `MedicationKnowledge.ingredient.item[x]` (new:CodeableConcept, Reference(Substance))",
        "comment": "Element `MedicationKnowledge.ingredient.item[x]` is part of an existing definition because parent element `MedicationKnowledge.ingredient` requires a cross-version extension.\nElement `MedicationKnowledge.ingredient.item[x]` has a context of MedicationKnowledge based on following the parent source element upwards and mapping to `MedicationKnowledge`.\nElement `MedicationKnowledge.ingredient.item[x]` has no mapping targets in FHIR R5. Typically, this is because the element has been added (is a new element).",
        "requirements": "Element `MedicationKnowledge.ingredient.item[x]` is part of an existing definition because parent element `MedicationKnowledge.ingredient` requires a cross-version extension.\nElement `MedicationKnowledge.ingredient.item[x]` has a context of MedicationKnowledge based on following the parent source element upwards and mapping to `MedicationKnowledge`.\nElement `MedicationKnowledge.ingredient.item[x]` has no mapping targets in FHIR R5. Typically, this is because the element has been added (is a new element).",
        "min": 1,
        "max": "1",
        "base": {
          "path": "Extension.extension",
          "min": 0,
          "max": "*"
        }
      },
      {
        "id": "Extension.extension:item.url",
        "path": "Extension.extension.url",
        "min": 1,
        "max": "1",
        "base": {
          "path": "Extension.url",
          "min": 1,
          "max": "1"
        },
        "fixedUri": "item"
      },
      {
        "id": "Extension.extension:item.value[x]",
        "path": "Extension.extension.value[x]",
        "short": "Medication(s) or substance(s) contained in the medication",
        "definition": "The actual ingredient - either a substance (simple ingredient) or another medication.",
        "min": 1,
        "max": "1",
        "base": {
          "path": "Extension.value[x]",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "CodeableConcept"
          },
          {
            "code": "Reference",
            "targetProfile": [
              "http://hl7.org/fhir/4.3/StructureDefinition/profile-Substance|0.1.0",
              "http://hl7.org/fhir/StructureDefinition/Substance|5.0.0"
            ]
          }
        ]
      },
      {
        "id": "Extension.extension:isActive",
        "path": "Extension.extension",
        "sliceName": "isActive",
        "short": "R4B: Active ingredient indicator (new)",
        "definition": "R4B: `MedicationKnowledge.ingredient.isActive` (new:boolean)",
        "comment": "Element `MedicationKnowledge.ingredient.isActive` is part of an existing definition because parent element `MedicationKnowledge.ingredient` requires a cross-version extension.\nElement `MedicationKnowledge.ingredient.isActive` has a context of MedicationKnowledge based on following the parent source element upwards and mapping to `MedicationKnowledge`.\nElement `MedicationKnowledge.ingredient.isActive` has no mapping targets in FHIR R5. Typically, this is because the element has been added (is a new element).",
        "requirements": "True indicates that the ingredient affects the therapeutic action of the drug (i.e. active). \rFalse indicates that the ingredient does not affect the therapeutic action of the drug (i.e. inactive). Element `MedicationKnowledge.ingredient.isActive` is part of an existing definition because parent element `MedicationKnowledge.ingredient` requires a cross-version extension.\nElement `MedicationKnowledge.ingredient.isActive` has a context of MedicationKnowledge based on following the parent source element upwards and mapping to `MedicationKnowledge`.\nElement `MedicationKnowledge.ingredient.isActive` has no mapping targets in FHIR R5. Typically, this is because the element has been added (is a new element).",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Extension.extension",
          "min": 0,
          "max": "*"
        }
      },
      {
        "id": "Extension.extension:isActive.url",
        "path": "Extension.extension.url",
        "min": 1,
        "max": "1",
        "base": {
          "path": "Extension.url",
          "min": 1,
          "max": "1"
        },
        "fixedUri": "isActive"
      },
      {
        "id": "Extension.extension:isActive.value[x]",
        "path": "Extension.extension.value[x]",
        "short": "Active ingredient indicator",
        "definition": "Indication of whether this ingredient affects the therapeutic action of the drug.",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Extension.value[x]",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "boolean"
          }
        ]
      },
      {
        "id": "Extension.extension:strength",
        "path": "Extension.extension",
        "sliceName": "strength",
        "short": "R4B: Quantity of ingredient present (new)",
        "definition": "R4B: `MedicationKnowledge.ingredient.strength` (new:Ratio)",
        "comment": "Element `MedicationKnowledge.ingredient.strength` is part of an existing definition because parent element `MedicationKnowledge.ingredient` requires a cross-version extension.\nElement `MedicationKnowledge.ingredient.strength` has a context of MedicationKnowledge based on following the parent source element upwards and mapping to `MedicationKnowledge`.\nElement `MedicationKnowledge.ingredient.strength` has no mapping targets in FHIR R5. Typically, this is because the element has been added (is a new element).",
        "requirements": "Element `MedicationKnowledge.ingredient.strength` is part of an existing definition because parent element `MedicationKnowledge.ingredient` requires a cross-version extension.\nElement `MedicationKnowledge.ingredient.strength` has a context of MedicationKnowledge based on following the parent source element upwards and mapping to `MedicationKnowledge`.\nElement `MedicationKnowledge.ingredient.strength` has no mapping targets in FHIR R5. Typically, this is because the element has been added (is a new element).",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Extension.extension",
          "min": 0,
          "max": "*"
        }
      },
      {
        "id": "Extension.extension:strength.url",
        "path": "Extension.extension.url",
        "min": 1,
        "max": "1",
        "base": {
          "path": "Extension.url",
          "min": 1,
          "max": "1"
        },
        "fixedUri": "strength"
      },
      {
        "id": "Extension.extension:strength.value[x]",
        "path": "Extension.extension.value[x]",
        "short": "Quantity of ingredient present",
        "definition": "Specifies how many (or how much) of the items there are in this Medication.  For example, 250 mg per tablet.  This is expressed as a ratio where the numerator is 250mg and the denominator is 1 tablet.",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Extension.value[x]",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "Ratio"
          }
        ]
      },
      {
        "id": "Extension.url",
        "path": "Extension.url",
        "min": 1,
        "max": "1",
        "base": {
          "path": "Extension.url",
          "min": 1,
          "max": "1"
        },
        "fixedUri": "http://hl7.org/fhir/4.3/StructureDefinition/extension-MedicationKnowledge.ingredient"
      },
      {
        "id": "Extension.value[x]",
        "path": "Extension.value[x]",
        "min": 0,
        "max": "0",
        "base": {
          "path": "Extension.value[x]",
          "min": 0,
          "max": "1"
        }
      }
    ]
  }
}