FHIR IG analytics| Package | hl7.fhir.uv.xver-r4.r4b |
| Resource Type | StructureDefinition |
| Id | StructureDefinition-profile-SubstanceNucleicAcid.json |
| FHIR Version | R4B |
| Source | http://hl7.org/fhir/uv/xver-r4.r4b/0.1.0/StructureDefinition-profile-SubstanceNucleicAcid.html |
| URL | http://hl7.org/fhir/4.0/StructureDefinition/profile-SubstanceNucleicAcid |
| Version | 0.1.0 |
| Status | active |
| Date | 2026-03-17T16:03:40.5981048-05:00 |
| Name | Profile_R4_SubstanceNucleicAcid_R4B |
| Title | Cross-version Profile for R4.SubstanceNucleicAcid for use in FHIR R4B |
| Realm | uv |
| Authority | hl7 |
| Description | This cross-version profile allows R4 SubstanceNucleicAcid content to be represented via FHIR R4B Basic resources. |
| Type | Basic |
| Kind | resource |
| StructureDefinition | ||
| hl7.fhir.uv.xver-r4.r4b#0.1.0 | extension-SubstanceSpecification.nucleicAcid | R4: Data items specific to nucleic acids (new) |
| StructureDefinition | ||
| hl7.fhir.uv.xver-r4.r4b#0.1.0 | extension-SubstanceNucleicAcid.areaOfHybridisation | R4: The area of hybridisation shall be described if applicable for double stranded RNA or DNA. The number associated with the subunit followed by the number associated to the residue shall be specified in increasing order. The underscore “” shall be used as separator as follows: “Subunitnumber Residue” (new) |
| hl7.fhir.uv.xver-r4.r4b#0.1.0 | extension-SubstanceNucleicAcid.numberOfSubunits | R4: The number of linear sequences of nucleotides linked through phosphodiester bonds shall be described. Subunits would be strands of nucleic acids that are tightly associated typically through Watson-Crick base pairing. NOTE: If not specified in the reference source, the assumption is that there is 1 subunit (new) |
| hl7.fhir.uv.xver-r4.r4b#0.1.0 | extension-SubstanceNucleicAcid.oligoNucleotideType | R4: (TBC) (new) |
| hl7.fhir.uv.xver-r4.r4b#0.1.0 | extension-SubstanceNucleicAcid.sequenceType | R4: The type of the sequence shall be specified based on a controlled vocabulary (new) |
| hl7.fhir.uv.xver-r4.r4b#0.1.0 | extension-SubstanceNucleicAcid.subunit | R4: Subunits are listed in order of decreasing length; sequences of the same length will be ordered by molecular weight; subunits that have identical sequences will be repeated multiple times (new) |
Note: links and images are rebased to the (stated) source
Generated Narrative: StructureDefinition profile-SubstanceNucleicAcid
| Name | Flags | Card. | Type | Description & Constraints |
|---|---|---|---|---|
  Basic | 0..* | Basic(4.3.0) | Resource for non-supported content | |
  Slices for extension | 0..* | Extension | Extension Slice: Unordered, Open by value:url | |
   extension:sequenceType | 0..1 | CodeableConcept | R4: The type of the sequence shall be specified based on a controlled vocabulary (new) URL: http://hl7.org/fhir/4.0/StructureDefinition/extension-SubstanceNucleicAcid.sequenceType | |
| extension:numberOfSubunits | 0..1 | integer | R4: The number of linear sequences of nucleotides linked through phosphodiester bonds shall be described. Subunits would be strands of nucleic acids that are tightly associated typically through Watson-Crick base pairing. NOTE: If not specified in the reference source, the assumption is that there is 1 subunit (new) URL: http://hl7.org/fhir/4.0/StructureDefinition/extension-SubstanceNucleicAcid.numberOfSubunits | |
| extension:areaOfHybridisation | 0..1 | string | R4: The area of hybridisation shall be described if applicable for double stranded RNA or DNA. The number associated with the subunit followed by the number associated to the residue shall be specified in increasing order. The underscore “” shall be used as separator as follows: “Subunitnumber Residue” (new) URL: http://hl7.org/fhir/4.0/StructureDefinition/extension-SubstanceNucleicAcid.areaOfHybridisation | |
| extension:oligoNucleotideType | 0..1 | CodeableConcept | R4: (TBC) (new) URL: http://hl7.org/fhir/4.0/StructureDefinition/extension-SubstanceNucleicAcid.oligoNucleotideType | |
 extension:subunit | 0..* | (Complex) | R4: Subunits are listed in order of decreasing length; sequences of the same length will be ordered by molecular weight; subunits that have identical sequences will be repeated multiple times (new) URL: http://hl7.org/fhir/4.0/StructureDefinition/extension-SubstanceNucleicAcid.subunit | |
| Documentation for this format | ||||
FHIR
FHIRsmith{
"resourceType": "StructureDefinition",
"id": "profile-SubstanceNucleicAcid",
"text": {
"status": "extensions",
"div": "<!-- snip (see above) -->"
},
"extension": [
{
"url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-wg",
"valueCode": "fhir"
},
{
"extension": [
{
"url": "packageId",
"valueId": "hl7.fhir.uv.xver-r4.r4b"
},
{
"url": "version",
"valueString": "0.1.0"
}
],
"url": "http://hl7.org/fhir/StructureDefinition/package-source"
},
{
"url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fmm",
"valueInteger": 0,
"_valueInteger": {
"extension": [
{
"url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-conformance-derivedFrom",
"valueCanonical": "http://hl7.org/fhir/uv/xver/ImplementationGuide/hl7.fhir.uv.xver-r4.r4b"
}
]
}
},
{
"url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status",
"valueCode": "trial-use",
"_valueCode": {
"extension": [
{
"url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-conformance-derivedFrom",
"valueCanonical": "http://hl7.org/fhir/uv/xver/ImplementationGuide/hl7.fhir.uv.xver-r4.r4b"
}
]
}
}
],
"url": "http://hl7.org/fhir/4.0/StructureDefinition/profile-SubstanceNucleicAcid",
"version": "0.1.0",
"name": "Profile_R4_SubstanceNucleicAcid_R4B",
"title": "Cross-version Profile for R4.SubstanceNucleicAcid for use in FHIR R4B",
"status": "active",
"experimental": false,
"date": "2026-03-17T16:03:40.5981048-05:00",
"publisher": "FHIR Infrastructure",
"contact": [
{
"name": "FHIR Infrastructure",
"telecom": [
{
"system": "url",
"value": "http://www.hl7.org/Special/committees/fiwg"
}
]
}
],
"description": "This cross-version profile allows R4 SubstanceNucleicAcid content to be represented via FHIR R4B Basic resources.",
"jurisdiction": [
{
"coding": [
{
"system": "http://unstats.un.org/unsd/methods/m49/m49.htm",
"code": "001",
"display": "World"
}
]
}
],
"fhirVersion": "4.3.0",
"mapping": [
{
"identity": "rim",
"uri": "http://hl7.org/v3",
"name": "RIM Mapping"
},
{
"identity": "w5",
"uri": "http://hl7.org/fhir/fivews",
"name": "FiveWs Pattern Mapping"
}
],
"kind": "resource",
"abstract": false,
"type": "Basic",
"baseDefinition": "http://hl7.org/fhir/StructureDefinition/Basic|4.3.0",
"derivation": "constraint",
"snapshot": {
"extension": [
{
"url": "http://hl7.org/fhir/tools/StructureDefinition/snapshot-base-version",
"valueString": "4.3.0"
}
],
"element": [
{
"id": "Basic",
"path": "Basic",
"short": "Resource for non-supported content",
"definition": "Basic is used for handling concepts not yet defined in FHIR, narrative-only resources that don't map to an existing resource, and custom resources not appropriate for inclusion in the FHIR specification.",
"alias": [
"Z-resource",
"Extension-resource",
"Custom-resource"
],
"min": 0,
"max": "*",
"base": {
"path": "Basic",
"min": 0,
"max": "*"
},
"constraint": [
{
"key": "dom-2",
"severity": "error",
"human": "If the resource is contained in another resource, it SHALL NOT contain nested Resources",
"expression": "contained.contained.empty()",
"xpath": "not(parent::f:contained and f:contained)",
"source": "http://hl7.org/fhir/StructureDefinition/DomainResource|4.3.0"
},
{
"key": "dom-3",
"severity": "error",
"human": "If the resource is contained in another resource, it SHALL be referred to from elsewhere in the resource or SHALL refer to the containing resource",
"expression": "contained.where(((id.exists() and ('#'+id in (%resource.descendants().reference | %resource.descendants().as(canonical) | %resource.descendants().as(uri) | %resource.descendants().as(url)))) or descendants().where(reference = '#').exists() or descendants().where(as(canonical) = '#').exists() or descendants().where(as(uri) = '#').exists()).not()).trace('unmatched', id).empty()",
"xpath": "not(exists(for $contained in f:contained return $contained[not(exists(parent::*/descendant::f:reference/@value=concat('#', $contained/*/f:id/@value)) or exists(descendant::f:reference[@value='#']))]))",
"source": "http://hl7.org/fhir/StructureDefinition/DomainResource|4.3.0"
},
{
"key": "dom-4",
"severity": "error",
"human": "If a resource is contained in another resource, it SHALL NOT have a meta.versionId or a meta.lastUpdated",
"expression": "contained.meta.versionId.empty() and contained.meta.lastUpdated.empty()",
"xpath": "not(exists(f:contained/*/f:meta/f:versionId)) and not(exists(f:contained/*/f:meta/f:lastUpdated))",
"source": "http://hl7.org/fhir/StructureDefinition/DomainResource|4.3.0"
},
{
"key": "dom-5",
"severity": "error",
"human": "If a resource is contained in another resource, it SHALL NOT have a security label",
"expression": "contained.meta.security.empty()",
"xpath": "not(exists(f:contained/*/f:meta/f:security))",
"source": "http://hl7.org/fhir/StructureDefinition/DomainResource|4.3.0"
},
{
"extension": [
{
"url": "http://hl7.org/fhir/StructureDefinition/elementdefinition-bestpractice",
"valueBoolean": true
},
{
"url": "http://hl7.org/fhir/StructureDefinition/elementdefinition-bestpractice-explanation",
"valueMarkdown": "When a resource has no narrative, only systems that fully understand the data can display the resource to a human safely. Including a human readable representation in the resource makes for a much more robust eco-system and cheaper handling of resources by intermediary systems. Some ecosystems restrict distribution of resources to only those systems that do fully understand the resources, and as a consequence implementers may believe that the narrative is superfluous. However experience shows that such eco-systems often open up to new participants over time."
}
],
"key": "dom-6",
"severity": "warning",
"human": "A resource should have narrative for robust management",
"expression": "text.`div`.exists()",
"xpath": "exists(f:text/h:div)",
"source": "http://hl7.org/fhir/StructureDefinition/DomainResource|4.3.0"
}
],
"mustSupport": false,
"isModifier": false,
"isSummary": false,
"mapping": [
{
"identity": "rim",
"map": "Entity. Role, or Act"
},
{
"identity": "rim",
"map": "Act, Entity or Role"
},
{
"identity": "w5",
"map": "infrastructure.structure"
}
]
},
{
"id": "Basic.id",
"path": "Basic.id",
"short": "Logical id of this artifact",
"definition": "The logical id of the resource, as used in the URL for the resource. Once assigned, this value never changes.",
"comment": "The only time that a resource does not have an id is when it is being submitted to the server using a create operation.",
"min": 0,
"max": "1",
"base": {
"path": "Resource.id",
"min": 0,
"max": "1"
},
"type": [
{
"extension": [
{
"url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
"valueUrl": "id"
}
],
"code": "http://hl7.org/fhirpath/System.String"
}
],
"mustSupport": false,
"isModifier": false,
"isSummary": true
},
{
"id": "Basic.meta",
"path": "Basic.meta",
"short": "Metadata about the resource",
"definition": "The metadata about the resource. This is content that is maintained by the infrastructure. Changes to the content might not always be associated with version changes to the resource.",
"min": 0,
"max": "1",
"base": {
"path": "Resource.meta",
"min": 0,
"max": "1"
},
"type": [
{
"code": "Meta"
}
],
"constraint": [
{
"key": "ele-1",
"severity": "error",
"human": "All FHIR elements must have a @value or children",
"expression": "hasValue() or (children().count() > id.count())",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element|4.3.0"
}
],
"mustSupport": false,
"isModifier": false,
"isSummary": true
},
{
"id": "Basic.implicitRules",
"path": "Basic.implicitRules",
"short": "A set of rules under which this content was created",
"definition": "A reference to a set of rules that were followed when the resource was constructed, and which must be understood when processing the content. Often, this is a reference to an implementation guide that defines the special rules along with other profiles etc.",
"comment": "Asserting this rule set restricts the content to be only understood by a limited set of trading partners. This inherently limits the usefulness of the data in the long term. However, the existing health eco-system is highly fractured, and not yet ready to define, collect, and exchange data in a generally computable sense. Wherever possible, implementers and/or specification writers should avoid using this element. Often, when used, the URL is a reference to an implementation guide that defines these special rules as part of it's narrative along with other profiles, value sets, etc.",
"min": 0,
"max": "1",
"base": {
"path": "Resource.implicitRules",
"min": 0,
"max": "1"
},
"type": [
{
"code": "uri"
}
],
"constraint": [
{
"key": "ele-1",
"severity": "error",
"human": "All FHIR elements must have a @value or children",
"expression": "hasValue() or (children().count() > id.count())",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element|4.3.0"
}
],
"mustSupport": false,
"isModifier": true,
"isModifierReason": "This element is labeled as a modifier because the implicit rules may provide additional knowledge about the resource that modifies it's meaning or interpretation",
"isSummary": true
},
{
"id": "Basic.language",
"path": "Basic.language",
"short": "Language of the resource content",
"definition": "The base language in which the resource is written.",
"comment": "Language is provided to support indexing and accessibility (typically, services such as text to speech use the language tag). The html language tag in the narrative applies to the narrative. The language tag on the resource may be used to specify the language of other presentations generated from the data in the resource. Not all the content has to be in the base language. The Resource.language should not be assumed to apply to the narrative automatically. If a language is specified, it should it also be specified on the div element in the html (see rules in HTML5 for information about the relationship between xml:lang and the html lang attribute).",
"min": 0,
"max": "1",
"base": {
"path": "Resource.language",
"min": 0,
"max": "1"
},
"type": [
{
"code": "code"
}
],
"constraint": [
{
"key": "ele-1",
"severity": "error",
"human": "All FHIR elements must have a @value or children",
"expression": "hasValue() or (children().count() > id.count())",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element|4.3.0"
}
],
"mustSupport": false,
"isModifier": false,
"isSummary": false,
"binding": {
"extension": [
{
"url": "http://hl7.org/fhir/StructureDefinition/elementdefinition-maxValueSet",
"valueCanonical": "http://hl7.org/fhir/ValueSet/all-languages|4.3.0"
},
{
"url": "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName",
"valueString": "Language"
}
],
"strength": "preferred",
"description": "IETF language tag",
"valueSet": "http://hl7.org/fhir/ValueSet/languages|4.3.0"
}
},
{
"id": "Basic.text",
"path": "Basic.text",
"short": "Text summary of the resource, for human interpretation",
"definition": "A human-readable narrative that contains a summary of the resource and can be used to represent the content of the resource to a human. The narrative need not encode all the structured data, but is required to contain sufficient detail to make it \"clinically safe\" for a human to just read the narrative. Resource definitions may define what content should be represented in the narrative to ensure clinical safety.",
"comment": "Contained resources do not have narrative. Resources that are not contained SHOULD have a narrative. In some cases, a resource may only have text with little or no additional discrete data (as long as all minOccurs=1 elements are satisfied). This may be necessary for data from legacy systems where information is captured as a \"text blob\" or where text is additionally entered raw or narrated and encoded information is added later.",
"alias": [
"narrative",
"html",
"xhtml",
"display"
],
"min": 0,
"max": "1",
"base": {
"path": "DomainResource.text",
"min": 0,
"max": "1"
},
"type": [
{
"code": "Narrative"
}
],
"constraint": [
{
"key": "ele-1",
"severity": "error",
"human": "All FHIR elements must have a @value or children",
"expression": "hasValue() or (children().count() > id.count())",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element|4.3.0"
}
],
"mustSupport": false,
"isModifier": false,
"isSummary": false,
"mapping": [
{
"identity": "rim",
"map": "Act.text?"
}
]
},
{
"id": "Basic.contained",
"path": "Basic.contained",
"short": "Contained, inline Resources",
"definition": "These resources do not have an independent existence apart from the resource that contains them - they cannot be identified independently, and nor can they have their own independent transaction scope.",
"comment": "This should never be done when the content can be identified properly, as once identification is lost, it is extremely difficult (and context dependent) to restore it again. Contained resources may have profiles and tags In their meta elements, but SHALL NOT have security labels.",
"alias": [
"inline resources",
"anonymous resources",
"contained resources"
],
"min": 0,
"max": "*",
"base": {
"path": "DomainResource.contained",
"min": 0,
"max": "*"
},
"type": [
{
"code": "Resource"
}
],
"constraint": [
{
"key": "dom-r4b",
"severity": "warning",
"human": "Containing new R4B resources within R4 resources may cause interoperability issues if instances are shared with R4 systems",
"expression": "($this is Citation or $this is Evidence or $this is EvidenceReport or $this is EvidenceVariable or $this is MedicinalProductDefinition or $this is PackagedProductDefinition or $this is AdministrableProductDefinition or $this is Ingredient or $this is ClinicalUseDefinition or $this is RegulatedAuthorization or $this is SubstanceDefinition or $this is SubscriptionStatus or $this is SubscriptionTopic) implies (%resource is Citation or %resource is Evidence or %resource is EvidenceReport or %resource is EvidenceVariable or %resource is MedicinalProductDefinition or %resource is PackagedProductDefinition or %resource is AdministrableProductDefinition or %resource is Ingredient or %resource is ClinicalUseDefinition or %resource is RegulatedAuthorization or %resource is SubstanceDefinition or %resource is SubscriptionStatus or %resource is SubscriptionTopic)",
"xpath": "not(f:Citation|f:Evidence|f:EvidenceReport|f:EvidenceVariable|f:MedicinalProductDefinition|f:PackagedProductDefinition|f:AdministrableProductDefinition|f:Ingredient|f:ClinicalUseDefinition|f:RegulatedAuthorization|f:SubstanceDefinition|f:SubscriptionStatus|f:SubscriptionTopic) or not(parent::f:Citation|parent::f:Evidence|parent::f:EvidenceReport|parent::f:EvidenceVariable|parent::f:MedicinalProductDefinition|parent::f:PackagedProductDefinition|parent::f:AdministrableProductDefinition|parent::f:Ingredient|parent::f:ClinicalUseDefinition|parent::f:RegulatedAuthorization|parent::f:SubstanceDefinition|f:SubscriptionStatus|f:SubscriptionTopic)",
"source": "http://hl7.org/fhir/StructureDefinition/Basic|4.3.0"
}
],
"mustSupport": false,
"isModifier": false,
"isSummary": false,
"mapping": [
{
"identity": "rim",
"map": "N/A"
}
]
},
{
"id": "Basic.extension",
"path": "Basic.extension",
"slicing": {
"discriminator": [
{
"type": "value",
"path": "url"
}
],
"ordered": false,
"rules": "open"
},
"short": "Extension",
"definition": "An Extension",
"min": 0,
"max": "*",
"base": {
"path": "DomainResource.extension",
"min": 0,
"max": "*"
},
"type": [
{
"code": "Extension"
}
],
"constraint": [
{
"key": "ele-1",
"severity": "error",
"human": "All FHIR elements must have a @value or children",
"expression": "hasValue() or (children().count() > id.count())",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element|4.3.0"
},
{
"key": "ext-1",
"severity": "error",
"human": "Must have either extensions or value[x], not both",
"expression": "extension.exists() != value.exists()",
"xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
"source": "http://hl7.org/fhir/StructureDefinition/Extension|4.3.0"
}
],
"mustSupport": false,
"isModifier": false,
"isSummary": false
},
{
"id": "Basic.extension:sequenceType",
"path": "Basic.extension",
"sliceName": "sequenceType",
"short": "R4: The type of the sequence shall be specified based on a controlled vocabulary (new)",
"definition": "R4: `SubstanceNucleicAcid.sequenceType` (new:CodeableConcept)",
"comment": "Element `SubstanceNucleicAcid.sequenceType` is not mapped to FHIR R4B, since FHIR R4 `SubstanceNucleicAcid` is not mapped.\nElement `SubstanceNucleicAcid.sequenceType` has no mapping targets in FHIR R4B. Typically, this is because the element has been added (is a new element).",
"min": 0,
"max": "1",
"base": {
"path": "DomainResource.extension",
"min": 0,
"max": "*"
},
"type": [
{
"code": "Extension",
"profile": [
"http://hl7.org/fhir/4.0/StructureDefinition/extension-SubstanceNucleicAcid.sequenceType|0.1.0"
]
}
],
"condition": [
"ele-1"
],
"constraint": [
{
"key": "ele-1",
"severity": "error",
"human": "All FHIR elements must have a @value or children unless an empty Parameters resource",
"expression": "hasValue() or (children().count() > id.count()) or $this is Parameters",
"xpath": "@value|f:*|h:div|self::f:Parameters",
"source": "http://hl7.org/fhir/StructureDefinition/Element|4.3.0"
},
{
"key": "ext-1",
"severity": "error",
"human": "Must have either extensions or value[x], not both",
"expression": "extension.exists() != value.exists()",
"xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), 'value')])",
"source": "http://hl7.org/fhir/StructureDefinition/Extension|4.3.0"
}
],
"mustSupport": false,
"isModifier": false,
"isSummary": false
},
{
"id": "Basic.extension:numberOfSubunits",
"path": "Basic.extension",
"sliceName": "numberOfSubunits",
"short": "R4: The number of linear sequences of nucleotides linked through phosphodiester bonds shall be described. Subunits would be strands of nucleic acids that are tightly associated typically through Watson-Crick base pairing. NOTE: If not specified in the reference source, the assumption is that there is 1 subunit (new)",
"definition": "R4: `SubstanceNucleicAcid.numberOfSubunits` (new:integer)",
"comment": "Element `SubstanceNucleicAcid.numberOfSubunits` is not mapped to FHIR R4B, since FHIR R4 `SubstanceNucleicAcid` is not mapped.\nElement `SubstanceNucleicAcid.numberOfSubunits` has no mapping targets in FHIR R4B. Typically, this is because the element has been added (is a new element).",
"min": 0,
"max": "1",
"base": {
"path": "DomainResource.extension",
"min": 0,
"max": "*"
},
"type": [
{
"code": "Extension",
"profile": [
"http://hl7.org/fhir/4.0/StructureDefinition/extension-SubstanceNucleicAcid.numberOfSubunits|0.1.0"
]
}
],
"condition": [
"ele-1"
],
"constraint": [
{
"key": "ele-1",
"severity": "error",
"human": "All FHIR elements must have a @value or children unless an empty Parameters resource",
"expression": "hasValue() or (children().count() > id.count()) or $this is Parameters",
"xpath": "@value|f:*|h:div|self::f:Parameters",
"source": "http://hl7.org/fhir/StructureDefinition/Element|4.3.0"
},
{
"key": "ext-1",
"severity": "error",
"human": "Must have either extensions or value[x], not both",
"expression": "extension.exists() != value.exists()",
"xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), 'value')])",
"source": "http://hl7.org/fhir/StructureDefinition/Extension|4.3.0"
}
],
"mustSupport": false,
"isModifier": false,
"isSummary": false
},
{
"id": "Basic.extension:areaOfHybridisation",
"path": "Basic.extension",
"sliceName": "areaOfHybridisation",
"short": "R4: The area of hybridisation shall be described if applicable for double stranded RNA or DNA. The number associated with the subunit followed by the number associated to the residue shall be specified in increasing order. The underscore “” shall be used as separator as follows: “Subunitnumber Residue” (new)",
"definition": "R4: `SubstanceNucleicAcid.areaOfHybridisation` (new:string)",
"comment": "Element `SubstanceNucleicAcid.areaOfHybridisation` is not mapped to FHIR R4B, since FHIR R4 `SubstanceNucleicAcid` is not mapped.\nElement `SubstanceNucleicAcid.areaOfHybridisation` has no mapping targets in FHIR R4B. Typically, this is because the element has been added (is a new element).",
"min": 0,
"max": "1",
"base": {
"path": "DomainResource.extension",
"min": 0,
"max": "*"
},
"type": [
{
"code": "Extension",
"profile": [
"http://hl7.org/fhir/4.0/StructureDefinition/extension-SubstanceNucleicAcid.areaOfHybridisation|0.1.0"
]
}
],
"condition": [
"ele-1"
],
"constraint": [
{
"key": "ele-1",
"severity": "error",
"human": "All FHIR elements must have a @value or children unless an empty Parameters resource",
"expression": "hasValue() or (children().count() > id.count()) or $this is Parameters",
"xpath": "@value|f:*|h:div|self::f:Parameters",
"source": "http://hl7.org/fhir/StructureDefinition/Element|4.3.0"
},
{
"key": "ext-1",
"severity": "error",
"human": "Must have either extensions or value[x], not both",
"expression": "extension.exists() != value.exists()",
"xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), 'value')])",
"source": "http://hl7.org/fhir/StructureDefinition/Extension|4.3.0"
}
],
"mustSupport": false,
"isModifier": false,
"isSummary": false
},
{
"id": "Basic.extension:oligoNucleotideType",
"path": "Basic.extension",
"sliceName": "oligoNucleotideType",
"short": "R4: (TBC) (new)",
"definition": "R4: `SubstanceNucleicAcid.oligoNucleotideType` (new:CodeableConcept)",
"comment": "Element `SubstanceNucleicAcid.oligoNucleotideType` is not mapped to FHIR R4B, since FHIR R4 `SubstanceNucleicAcid` is not mapped.\nElement `SubstanceNucleicAcid.oligoNucleotideType` has no mapping targets in FHIR R4B. Typically, this is because the element has been added (is a new element).",
"min": 0,
"max": "1",
"base": {
"path": "DomainResource.extension",
"min": 0,
"max": "*"
},
"type": [
{
"code": "Extension",
"profile": [
"http://hl7.org/fhir/4.0/StructureDefinition/extension-SubstanceNucleicAcid.oligoNucleotideType|0.1.0"
]
}
],
"condition": [
"ele-1"
],
"constraint": [
{
"key": "ele-1",
"severity": "error",
"human": "All FHIR elements must have a @value or children unless an empty Parameters resource",
"expression": "hasValue() or (children().count() > id.count()) or $this is Parameters",
"xpath": "@value|f:*|h:div|self::f:Parameters",
"source": "http://hl7.org/fhir/StructureDefinition/Element|4.3.0"
},
{
"key": "ext-1",
"severity": "error",
"human": "Must have either extensions or value[x], not both",
"expression": "extension.exists() != value.exists()",
"xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), 'value')])",
"source": "http://hl7.org/fhir/StructureDefinition/Extension|4.3.0"
}
],
"mustSupport": false,
"isModifier": false,
"isSummary": false
},
{
"id": "Basic.extension:subunit",
"path": "Basic.extension",
"sliceName": "subunit",
"short": "R4: Subunits are listed in order of decreasing length; sequences of the same length will be ordered by molecular weight; subunits that have identical sequences will be repeated multiple times (new)",
"definition": "R4: `SubstanceNucleicAcid.subunit` (new:BackboneElement)",
"comment": "Element `SubstanceNucleicAcid.subunit` is not mapped to FHIR R4B, since FHIR R4 `SubstanceNucleicAcid` is not mapped.\nElement `SubstanceNucleicAcid.subunit` has no mapping targets in FHIR R4B. Typically, this is because the element has been added (is a new element).",
"min": 0,
"max": "*",
"base": {
"path": "DomainResource.extension",
"min": 0,
"max": "*"
},
"type": [
{
"code": "Extension",
"profile": [
"http://hl7.org/fhir/4.0/StructureDefinition/extension-SubstanceNucleicAcid.subunit|0.1.0"
]
}
],
"condition": [
"ele-1"
],
"constraint": [
{
"key": "ele-1",
"severity": "error",
"human": "All FHIR elements must have a @value or children unless an empty Parameters resource",
"expression": "hasValue() or (children().count() > id.count()) or $this is Parameters",
"xpath": "@value|f:*|h:div|self::f:Parameters",
"source": "http://hl7.org/fhir/StructureDefinition/Element|4.3.0"
},
{
"key": "ext-1",
"severity": "error",
"human": "Must have either extensions or value[x], not both",
"expression": "extension.exists() != value.exists()",
"xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), 'value')])",
"source": "http://hl7.org/fhir/StructureDefinition/Extension|4.3.0"
}
],
"mustSupport": false,
"isModifier": false,
"isSummary": false
},
{
"id": "Basic.modifierExtension",
"path": "Basic.modifierExtension",
"short": "Extensions that cannot be ignored",
"definition": "May be used to represent additional information that is not part of the basic definition of the resource and that modifies the understanding of the element that contains it and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer is allowed to define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.\n\nModifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).",
"comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
"requirements": "Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](http://hl7.org/fhir/R4B/extensibility.html#modifierExtension).",
"alias": [
"extensions",
"user content"
],
"min": 0,
"max": "*",
"base": {
"path": "DomainResource.modifierExtension",
"min": 0,
"max": "*"
},
"type": [
{
"code": "Extension"
}
],
"constraint": [
{
"key": "ele-1",
"severity": "error",
"human": "All FHIR elements must have a @value or children",
"expression": "hasValue() or (children().count() > id.count())",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element|4.3.0"
},
{
"key": "ext-1",
"severity": "error",
"human": "Must have either extensions or value[x], not both",
"expression": "extension.exists() != value.exists()",
"xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
"source": "http://hl7.org/fhir/StructureDefinition/Extension|4.3.0"
}
],
"mustSupport": false,
"isModifier": true,
"isModifierReason": "Modifier extensions are expected to modify the meaning or interpretation of the resource that contains them",
"isSummary": false,
"mapping": [
{
"identity": "rim",
"map": "N/A"
}
]
},
{
"id": "Basic.identifier",
"path": "Basic.identifier",
"short": "Business identifier",
"definition": "Identifier assigned to the resource for business purposes, outside the context of FHIR.",
"min": 0,
"max": "*",
"base": {
"path": "Basic.identifier",
"min": 0,
"max": "*"
},
"type": [
{
"code": "Identifier"
}
],
"constraint": [
{
"key": "ele-1",
"severity": "error",
"human": "All FHIR elements must have a @value or children",
"expression": "hasValue() or (children().count() > id.count())",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element|4.3.0"
}
],
"mustSupport": false,
"isModifier": false,
"isSummary": true,
"mapping": [
{
"identity": "w5",
"map": "FiveWs.identifier"
},
{
"identity": "rim",
"map": "./identifier"
}
]
},
{
"id": "Basic.code",
"path": "Basic.code",
"short": "Kind of Resource",
"definition": "Identifies the 'type' of resource - equivalent to the resource name for other resources.",
"comment": "Because resource references will only be able to indicate 'Basic', the type of reference will need to be specified in a Profile identified as part of the resource. Refer to the resource notes section for information on appropriate terminologies for this code.\n\nThis element is labeled as a modifier because it defines the meaning of the resource and cannot be ignored.",
"requirements": "Must be able to distinguish different types of Basic resources.",
"min": 1,
"max": "1",
"base": {
"path": "Basic.code",
"min": 1,
"max": "1"
},
"type": [
{
"code": "CodeableConcept"
}
],
"constraint": [
{
"key": "ele-1",
"severity": "error",
"human": "All FHIR elements must have a @value or children",
"expression": "hasValue() or (children().count() > id.count())",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element|4.3.0"
}
],
"mustSupport": false,
"isModifier": true,
"isModifierReason": "This element determines what kind of resource is being represented which drives the meaning of all of the other elements.",
"isSummary": true,
"binding": {
"extension": [
{
"url": "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName",
"valueString": "BasicResourceType"
}
],
"strength": "example",
"description": "HL7-maintained set of codes for \"Basic\" resources",
"valueSet": "http://hl7.org/fhir/ValueSet/basic-resource-type|4.3.0"
},
"mapping": [
{
"identity": "w5",
"map": "FiveWs.what[x]"
},
{
"identity": "rim",
"map": "./code"
}
]
},
{
"id": "Basic.subject",
"path": "Basic.subject",
"short": "Identifies the focus of this resource",
"definition": "Identifies the patient, practitioner, device or any other resource that is the \"focus\" of this resource.",
"comment": "Optional as not all potential resources will have subjects. Resources associated with multiple subjects can handle this via extension.",
"requirements": "Needed for partitioning the resource by Patient.",
"min": 0,
"max": "1",
"base": {
"path": "Basic.subject",
"min": 0,
"max": "1"
},
"type": [
{
"code": "Reference",
"targetProfile": [
"http://hl7.org/fhir/StructureDefinition/Resource|4.3.0"
]
}
],
"constraint": [
{
"key": "ele-1",
"severity": "error",
"human": "All FHIR elements must have a @value or children",
"expression": "hasValue() or (children().count() > id.count())",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element|4.3.0"
}
],
"mustSupport": false,
"isModifier": false,
"isSummary": true,
"mapping": [
{
"identity": "w5",
"map": "FiveWs.subject[x]"
},
{
"identity": "rim",
"map": "./participation[typeCode='SBJ'] (possibly through a ControlAct and Role)"
},
{
"identity": "w5",
"map": "FiveWs.subject"
}
]
},
{
"id": "Basic.created",
"path": "Basic.created",
"short": "When created",
"definition": "Identifies when the resource was first created.",
"requirements": "Allows ordering resource instances by time.",
"min": 0,
"max": "1",
"base": {
"path": "Basic.created",
"min": 0,
"max": "1"
},
"type": [
{
"code": "date"
}
],
"constraint": [
{
"key": "ele-1",
"severity": "error",
"human": "All FHIR elements must have a @value or children",
"expression": "hasValue() or (children().count() > id.count())",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element|4.3.0"
}
],
"mustSupport": false,
"isModifier": false,
"isSummary": true,
"mapping": [
{
"identity": "w5",
"map": "FiveWs.recorded"
},
{
"identity": "rim",
"map": "./participation[typeCode='AUT']/time (possibly through a ControlAct and Role)"
}
]
},
{
"id": "Basic.author",
"path": "Basic.author",
"short": "Who created",
"definition": "Indicates who was responsible for creating the resource instance.",
"requirements": "Needed for partitioning the resource.",
"min": 0,
"max": "1",
"base": {
"path": "Basic.author",
"min": 0,
"max": "1"
},
"type": [
{
"code": "Reference",
"targetProfile": [
"http://hl7.org/fhir/StructureDefinition/Practitioner|4.3.0",
"http://hl7.org/fhir/StructureDefinition/PractitionerRole|4.3.0",
"http://hl7.org/fhir/StructureDefinition/Patient|4.3.0",
"http://hl7.org/fhir/StructureDefinition/RelatedPerson|4.3.0",
"http://hl7.org/fhir/StructureDefinition/Organization|4.3.0"
]
}
],
"constraint": [
{
"key": "ele-1",
"severity": "error",
"human": "All FHIR elements must have a @value or children",
"expression": "hasValue() or (children().count() > id.count())",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element|4.3.0"
}
],
"mustSupport": false,
"isModifier": false,
"isSummary": true,
"mapping": [
{
"identity": "w5",
"map": "FiveWs.author"
},
{
"identity": "rim",
"map": "./participation[typeCode='SUB'] (possibly through a ControlAct and Role)"
}
]
}
]
},
"differential": {
"element": [
{
"id": "Basic",
"path": "Basic"
},
{
"id": "Basic.extension",
"path": "Basic.extension",
"slicing": {
"discriminator": [
{
"type": "value",
"path": "url"
}
],
"ordered": false,
"rules": "open"
},
"min": 0,
"max": "*"
},
{
"id": "Basic.extension:sequenceType",
"path": "Basic.extension",
"sliceName": "sequenceType",
"short": "R4: The type of the sequence shall be specified based on a controlled vocabulary (new)",
"definition": "R4: `SubstanceNucleicAcid.sequenceType` (new:CodeableConcept)",
"comment": "Element `SubstanceNucleicAcid.sequenceType` is not mapped to FHIR R4B, since FHIR R4 `SubstanceNucleicAcid` is not mapped.\nElement `SubstanceNucleicAcid.sequenceType` has no mapping targets in FHIR R4B. Typically, this is because the element has been added (is a new element).",
"min": 0,
"max": "1",
"base": {
"path": "DomainResource.extension",
"min": 0,
"max": "*"
},
"type": [
{
"code": "Extension",
"profile": [
"http://hl7.org/fhir/4.0/StructureDefinition/extension-SubstanceNucleicAcid.sequenceType|0.1.0"
]
}
]
},
{
"id": "Basic.extension:numberOfSubunits",
"path": "Basic.extension",
"sliceName": "numberOfSubunits",
"short": "R4: The number of linear sequences of nucleotides linked through phosphodiester bonds shall be described. Subunits would be strands of nucleic acids that are tightly associated typically through Watson-Crick base pairing. NOTE: If not specified in the reference source, the assumption is that there is 1 subunit (new)",
"definition": "R4: `SubstanceNucleicAcid.numberOfSubunits` (new:integer)",
"comment": "Element `SubstanceNucleicAcid.numberOfSubunits` is not mapped to FHIR R4B, since FHIR R4 `SubstanceNucleicAcid` is not mapped.\nElement `SubstanceNucleicAcid.numberOfSubunits` has no mapping targets in FHIR R4B. Typically, this is because the element has been added (is a new element).",
"min": 0,
"max": "1",
"base": {
"path": "DomainResource.extension",
"min": 0,
"max": "*"
},
"type": [
{
"code": "Extension",
"profile": [
"http://hl7.org/fhir/4.0/StructureDefinition/extension-SubstanceNucleicAcid.numberOfSubunits|0.1.0"
]
}
]
},
{
"id": "Basic.extension:areaOfHybridisation",
"path": "Basic.extension",
"sliceName": "areaOfHybridisation",
"short": "R4: The area of hybridisation shall be described if applicable for double stranded RNA or DNA. The number associated with the subunit followed by the number associated to the residue shall be specified in increasing order. The underscore “” shall be used as separator as follows: “Subunitnumber Residue” (new)",
"definition": "R4: `SubstanceNucleicAcid.areaOfHybridisation` (new:string)",
"comment": "Element `SubstanceNucleicAcid.areaOfHybridisation` is not mapped to FHIR R4B, since FHIR R4 `SubstanceNucleicAcid` is not mapped.\nElement `SubstanceNucleicAcid.areaOfHybridisation` has no mapping targets in FHIR R4B. Typically, this is because the element has been added (is a new element).",
"min": 0,
"max": "1",
"base": {
"path": "DomainResource.extension",
"min": 0,
"max": "*"
},
"type": [
{
"code": "Extension",
"profile": [
"http://hl7.org/fhir/4.0/StructureDefinition/extension-SubstanceNucleicAcid.areaOfHybridisation|0.1.0"
]
}
]
},
{
"id": "Basic.extension:oligoNucleotideType",
"path": "Basic.extension",
"sliceName": "oligoNucleotideType",
"short": "R4: (TBC) (new)",
"definition": "R4: `SubstanceNucleicAcid.oligoNucleotideType` (new:CodeableConcept)",
"comment": "Element `SubstanceNucleicAcid.oligoNucleotideType` is not mapped to FHIR R4B, since FHIR R4 `SubstanceNucleicAcid` is not mapped.\nElement `SubstanceNucleicAcid.oligoNucleotideType` has no mapping targets in FHIR R4B. Typically, this is because the element has been added (is a new element).",
"min": 0,
"max": "1",
"base": {
"path": "DomainResource.extension",
"min": 0,
"max": "*"
},
"type": [
{
"code": "Extension",
"profile": [
"http://hl7.org/fhir/4.0/StructureDefinition/extension-SubstanceNucleicAcid.oligoNucleotideType|0.1.0"
]
}
]
},
{
"id": "Basic.extension:subunit",
"path": "Basic.extension",
"sliceName": "subunit",
"short": "R4: Subunits are listed in order of decreasing length; sequences of the same length will be ordered by molecular weight; subunits that have identical sequences will be repeated multiple times (new)",
"definition": "R4: `SubstanceNucleicAcid.subunit` (new:BackboneElement)",
"comment": "Element `SubstanceNucleicAcid.subunit` is not mapped to FHIR R4B, since FHIR R4 `SubstanceNucleicAcid` is not mapped.\nElement `SubstanceNucleicAcid.subunit` has no mapping targets in FHIR R4B. Typically, this is because the element has been added (is a new element).",
"min": 0,
"max": "*",
"base": {
"path": "DomainResource.extension",
"min": 0,
"max": "*"
},
"type": [
{
"code": "Extension",
"profile": [
"http://hl7.org/fhir/4.0/StructureDefinition/extension-SubstanceNucleicAcid.subunit|0.1.0"
]
}
]
}
]
}
}