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Packagehl7.fhir.uv.xver-r4.r3
Resource TypeValueSet
IdValueSet-R4-observation-interpretation-for-R3.json
FHIR VersionR3
Sourcehttp://hl7.org/fhir/uv/xver-r4.r3/0.1.0/ValueSet-R4-observation-interpretation-for-R3.html
URLhttp://hl7.org/fhir/uv/xver/ValueSet/R4-observation-interpretation-for-R3
Version0.1.0
Statusactive
Date2026-03-17T21:02:03.8104715+00:00
NameR4ObservationInterpretationForR3
TitleCross-version ValueSet R4.ObservationInterpretationCodes for use in FHIR STU3
Realmuv
Authorityhl7
DescriptionThis cross-version ValueSet represents content from http://hl7.org/fhir/ValueSet/observation-interpretation|4.0.1 for use in FHIR STU3 that is appropriate for use but unavailable in `http://hl7.org/fhir/ValueSet/observation-interpretation|3.0.2`.
PurposeThis value set is part of the cross-version definitions generated to enable use of the value set `http://hl7.org/fhir/ValueSet/observation-interpretation|4.0.1` as defined in FHIR R4 in FHIR STU3. The source value set is bound to the following FHIR R4 elements: * `Observation.component.interpretation` * `Observation.interpretation` Note that there are 31 concepts not included in this cross-version definition because they have valid representations. Following are the generation technical comments: One or more source concepts are either not mapped or broader than their targets, so the value set relationship is broadened. The source and target value sets have the same number of active concepts (39).

Resources that use this resource

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Resources that this resource uses

CodeSystem
hl7.terminology#currentv3-ObservationInterpretationObservationInterpretation

Narrative

Note: links and images are rebased to the (stated) source

Generated Narrative: ValueSet R4-observation-interpretation-for-R3

This value set expansion contains 8 concepts.

SystemVersionCodeDisplayDefinition
http://terminology.hl7.org/CodeSystem/v3-ObservationInterpretation2018-08-12  CARCarrier

The patient is considered as carrier based on the testing results. A carrier is an individual who carries an altered form of a gene which can lead to having a child or offspring in future generations with a genetic disorder.

http://terminology.hl7.org/CodeSystem/v3-ObservationInterpretation2018-08-12  EEquivocal

The test or procedure was successfully performed, but the results are borderline and can neither be declared positive / negative nor detected / not detected according to the current established criteria.

http://terminology.hl7.org/CodeSystem/v3-ObservationInterpretation2018-08-12  EXoutside threshold

The observation/test result is interpreted as being outside the inclusion range for a particular protocol within which the result is being reported.

                    Example: A positive result on a Hepatitis screening test.
                       Open Issue: EX, HX, LX: These three concepts do not seem to meet a clear need in the vocabulary, and their use in observation interpretation appears likely to be covered by other existing concepts (e.g., A, H, L).  The only apparent significant difference is their reference to use in protocols for exclusion of study subjects.

These concepts/codes were proposed by RCRIM for use in the CTLaboratory message. They were submitted and approved in the November 2005 Harmonization cycle in proposal "030103CVOCABRCRIMlquadeRCRIM Obs Interp20051028154455". However, this proposal was not fully implemented in the vocabulary. The proposal recommended creation of the x_ClinicalResearchExclusion domain in ObservationInterpretation with a value set including those three concepts/codes, but there is no subdomain of that name or equivalent with a binding to either of the value sets that contain these concepts/codes. Members of the OO WG have recently attempted to contact members of RCRIM regarding these concepts, both by email and at the recent WGM in Atlanta, without response. It is felt by OO that the best course of action to take at this time is to add this comprehensive Open Issue rather than deprecate these three concepts at this time, until further discussion is held.

http://terminology.hl7.org/CodeSystem/v3-ObservationInterpretation2018-08-12  EXPExpected

This result has been evaluated in light of known contraindicators. Once those contraindicators have been taken into account the result is determined to be "Expected" (e.g., presence of drugs in a patient that is taking prescription medication for pain management).

http://terminology.hl7.org/CodeSystem/v3-ObservationInterpretation2018-08-12  HXabove high threshold

The observation/test result is interpreted as being outside the inclusion range for a particular protocol within which the result is being reported.

                    Example: A positive result on a Hepatitis screening test.
                       Open Issue: EX, HX, LX: These three concepts do not seem to meet a clear need in the vocabulary, and their use in observation interpretation appears likely to be covered by other existing concepts (e.g., A, H, L).  The only apparent significant difference is their reference to use in protocols for exclusion of study subjects.  These concepts/codes were proposed by RCRIM for use in the CTLaboratory message.  They were submitted and approved in the November 2005 Harmonization cycle in proposal "030103C_VOCAB_RCRIM_l_quade_RCRIM Obs Interp_20051028154455". However, this proposal was not fully implemented in the vocabulary.  The proposal recommended creation of the x_ClinicalResearchExclusion domain in ObservationInterpretation with a value set including those three concepts/codes, but there is no subdomain of that name or equivalent with a binding to either of the value sets that contain these concepts/codes.  Members of the OO WG have recently attempted to contact members of RCRIM regarding these concepts, both by email and at the recent WGM in Atlanta, without response.  It is felt by OO that the best course of action to take at this time is to add this comprehensive Open Issue rather than deprecate these three concepts at this time, until further discussion is held.
http://terminology.hl7.org/CodeSystem/v3-ObservationInterpretation2018-08-12  LXbelow low threshold

The numeric observation/test result is interpreted as being below the low threshold value for a particular protocol within which the result is being reported.

                    Example: A Total White Blood Cell Count falling below a protocol-defined threshold value of 3000/mm^3
                       Open Issue: EX, HX, LX: These three concepts do not seem to meet a clear need in the vocabulary, and their use in observation interpretation appears likely to be covered by other existing concepts (e.g., A, H, L).  The only apparent significant difference is their reference to use in protocols for exclusion of study subjects.  These concepts/codes were proposed by RCRIM for use in the CTLaboratory message.  They were submitted and approved in the November 2005 Harmonization cycle in proposal "030103C_VOCAB_RCRIM_l_quade_RCRIM Obs Interp_20051028154455".  However, this proposal was not fully implemented in the vocabulary.  The proposal recommended creation of the x_ClinicalResearchExclusion domain in ObservationInterpretation with a value set including those three concepts/codes, but there is no subdomain of that name or equivalent with a binding to either of the value sets that contain these concepts/codes.  Members of the OO WG have recently attempted to contact members of RCRIM regarding these concepts, both by email and at the recent WGM in Atlanta, without response.  It is felt by OO that the best course of action to take at this time is to add this comprehensive Open Issue rather than deprecate these three concepts at this time, until further discussion is held.
http://terminology.hl7.org/CodeSystem/v3-ObservationInterpretation2018-08-12  NCLNo CLSI defined breakpoint

Use when not enough clinical trial data published by the Clinical and Laboratory Standards Institutes (CLSI) is available to establish the breakpoints for susceptible / intermediate and resistant.

http://terminology.hl7.org/CodeSystem/v3-ObservationInterpretation2018-08-12  UNEUnexpected

This result has been evaluated in light of known contraindicators. Once those contraindicators have been taken into account the result is determined to be "Unexpected" (e.g., presence of non-prescribed drugs in a patient that is taking prescription medication for pain management).


Source1

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  "id": "R4-observation-interpretation-for-R3",
  "text": {
    "status": "generated",
    "div": "<!-- snip (see above) -->"
  },
  "extension": [
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      "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fmm",
      "valueInteger": 5
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    {
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      "valueCode": "oo"
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    {
      "extension": [
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          "valueId": "hl7.fhir.uv.xver-r4.r3"
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          "url": "version",
          "valueString": "0.1.0"
        },
        {
          "url": "uri",
          "valueUri": "http://hl7.org/fhir/uv/xver/ImplementationGuide/hl7.fhir.uv.xver-r4.r3"
        }
      ],
      "url": "http://hl7.org/fhir/StructureDefinition/package-source"
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    {
      "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status",
      "valueCode": "trial-use",
      "_valueCode": {
        "extension": [
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          }
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  ],
  "url": "http://hl7.org/fhir/uv/xver/ValueSet/R4-observation-interpretation-for-R3",
  "version": "0.1.0",
  "name": "R4ObservationInterpretationForR3",
  "title": "Cross-version ValueSet R4.ObservationInterpretationCodes for use in FHIR STU3",
  "status": "active",
  "experimental": false,
  "date": "2026-03-17T21:02:03.8104715+00:00",
  "publisher": "Orders and Observations",
  "contact": [
    {
      "name": "Orders and Observations",
      "telecom": [
        {
          "system": "url",
          "value": "http://www.hl7.org/Special/committees/orders"
        }
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  "description": "This cross-version ValueSet represents content from http://hl7.org/fhir/ValueSet/observation-interpretation|4.0.1 for use in FHIR STU3 that is appropriate for use but unavailable in `http://hl7.org/fhir/ValueSet/observation-interpretation|3.0.2`.",
  "jurisdiction": [
    {
      "coding": [
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          "code": "001",
          "display": "World"
        }
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    }
  ],
  "purpose": "This value set is part of the cross-version definitions generated to enable use of the\r\nvalue set `http://hl7.org/fhir/ValueSet/observation-interpretation|4.0.1` as defined in FHIR R4\r\nin FHIR STU3.\r\n\r\nThe source value set is bound to the following FHIR R4 elements:\r\n* `Observation.component.interpretation`\n* `Observation.interpretation`\r\n\r\nNote that there are 31 concepts not included in this cross-version definition because they have valid representations.\r\n\r\nFollowing are the generation technical comments:\r\nOne or more source concepts are either not mapped or broader than their targets, so the value set relationship is broadened.\nThe source and target value sets have the same number of active concepts (39).",
  "compose": {
    "include": [
      {
        "system": "http://terminology.hl7.org/CodeSystem/v3-ObservationInterpretation",
        "version": "2018-08-12",
        "concept": [
          {
            "code": "CAR",
            "display": "Carrier"
          },
          {
            "code": "E",
            "display": "Equivocal"
          },
          {
            "code": "EX",
            "display": "outside threshold"
          },
          {
            "code": "EXP",
            "display": "Expected"
          },
          {
            "code": "HX",
            "display": "above high threshold"
          },
          {
            "code": "LX",
            "display": "below low threshold"
          },
          {
            "code": "NCL",
            "display": "No CLSI defined breakpoint"
          },
          {
            "code": "UNE",
            "display": "Unexpected"
          }
        ]
      }
    ]
  },
  "expansion": {
    "timestamp": "2026-03-17T21:02:03.8104715+00:00",
    "contains": [
      {
        "system": "http://terminology.hl7.org/CodeSystem/v3-ObservationInterpretation",
        "version": "2018-08-12",
        "code": "CAR",
        "display": "Carrier"
      },
      {
        "system": "http://terminology.hl7.org/CodeSystem/v3-ObservationInterpretation",
        "version": "2018-08-12",
        "code": "E",
        "display": "Equivocal"
      },
      {
        "system": "http://terminology.hl7.org/CodeSystem/v3-ObservationInterpretation",
        "version": "2018-08-12",
        "code": "EX",
        "display": "outside threshold"
      },
      {
        "system": "http://terminology.hl7.org/CodeSystem/v3-ObservationInterpretation",
        "version": "2018-08-12",
        "code": "EXP",
        "display": "Expected"
      },
      {
        "system": "http://terminology.hl7.org/CodeSystem/v3-ObservationInterpretation",
        "version": "2018-08-12",
        "code": "HX",
        "display": "above high threshold"
      },
      {
        "system": "http://terminology.hl7.org/CodeSystem/v3-ObservationInterpretation",
        "version": "2018-08-12",
        "code": "LX",
        "display": "below low threshold"
      },
      {
        "system": "http://terminology.hl7.org/CodeSystem/v3-ObservationInterpretation",
        "version": "2018-08-12",
        "code": "NCL",
        "display": "No CLSI defined breakpoint"
      },
      {
        "system": "http://terminology.hl7.org/CodeSystem/v3-ObservationInterpretation",
        "version": "2018-08-12",
        "code": "UNE",
        "display": "Unexpected"
      }
    ]
  }
}