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                       Discussion: The effect of the substance is typically established on a biochemical basis, however, that is not a requirement. For example, radiotherapy can largely be described in the same way, especially if it is a systemic therapy such as radio-iodine.  This class also includes the application of chemical treatments to an area.

                    
                       Examples: Chemotherapy protocol; Drug prescription; Vaccination record

                       Examples: : Procedures may involve the disruption of some body surface (e.g. an incision in a surgical procedure), but they also include conservative procedures such as reduction of a luxated join, chiropractic treatment, massage, balneotherapy, acupuncture, shiatsu, etc. Outside of clinical medicine, procedures may be such things as alteration of environments (e.g. straightening rivers, draining swamps, building dams) or the repair or change of machinery etc.

Source1

{
  "resourceType": "ValueSet",
  "id": "R3-v3-ActClassProcedure-for-R4B",
  "text": {
    "status": "generated",
    "div": "<!-- snip (see above) -->"
  },
  "extension": [
    {
      "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fmm",
      "valueInteger": 0
    },
    {
      "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-wg",
      "valueCode": "fhir"
    },
    {
      "extension": [
        {
          "url": "packageId",
          "valueId": "hl7.fhir.uv.xver-r3.r4b"
        },
        {
          "url": "version",
          "valueString": "0.0.1-snapshot-2"
        }
      ],
      "url": "http://hl7.org/fhir/StructureDefinition/package-source"
    },
    {
      "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status",
      "valueCode": "trial-use",
      "_valueCode": {
        "extension": [
          {
            "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-conformance-derivedFrom",
            "valueCanonical": "http://hl7.org/fhir/3.0/ImplementationGuide/hl7.fhir.uv.xver-r3.r4b"
          }
        ]
      }
    }
  ],
  "url": "http://hl7.org/fhir/3.0/ValueSet/R3-v3-ActClassProcedure-for-R4B",
  "version": "0.0.1-snapshot-2",
  "name": "R3_v3_ActClassProcedure_for_R4B",
  "title": "Cross-version VS for R3.ActClassProcedure for use in FHIR R4B",
  "status": "active",
  "experimental": false,
  "date": "2025-09-01T22:35:59.943526+10:00",
  "publisher": "FHIR Infrastructure",
  "contact": [
    {
      "name": "FHIR Infrastructure",
      "telecom": [
        {
          "system": "url",
          "value": "http://www.hl7.org/Special/committees/fiwg"
        }
      ]
    }
  ],
  "description": "This cross-version ValueSet represents concepts from http://hl7.org/fhir/ValueSet/v3-ActClassProcedure|2014-03-26 for use in FHIR R4B. Concepts not present here have direct `equivalent` mappings crossing all versions from R3 to R4B.",
  "jurisdiction": [
    {
      "coding": [
        {
          "system": "http://unstats.un.org/unsd/methods/m49/m49.htm",
          "code": "001",
          "display": "World"
        }
      ]
    }
  ],
  "compose": {
    "include": [
      {
        "system": "http://hl7.org/fhir/v3/ActClass",
        "version": "2016-11-11",
        "concept": [
          {
            "code": "SBADM",
            "display": "substance administration"
          },
          {
            "code": "SPECCOLLECT",
            "display": "Specimen Collection"
          },
          {
            "code": "SBEXT",
            "display": "Substance Extraction"
          },
          {
            "code": "PROC",
            "display": "procedure"
          }
        ]
      }
    ]
  },
  "expansion": {
    "timestamp": "2025-09-01T22:35:59.943524+10:00",
    "contains": [
      {
        "system": "http://hl7.org/fhir/v3/ActClass",
        "version": "2016-11-11",
        "code": "SBADM",
        "display": "substance administration"
      },
      {
        "system": "http://hl7.org/fhir/v3/ActClass",
        "version": "2016-11-11",
        "code": "SPECCOLLECT",
        "display": "Specimen Collection"
      },
      {
        "system": "http://hl7.org/fhir/v3/ActClass",
        "version": "2016-11-11",
        "code": "SBEXT",
        "display": "Substance Extraction"
      },
      {
        "system": "http://hl7.org/fhir/v3/ActClass",
        "version": "2016-11-11",
        "code": "PROC",
        "display": "procedure"
      }
    ]
  }
}