FHIR IG analytics| Package | hl7.fhir.uv.pharm-quality |
| Resource Type | Bundle |
| Id | Bundle-bundle-drug-substance-specification-pq-ex1.json |
| FHIR Version | R5 |
No resources found
No resources found
No narrative content found in resource
FHIR
FHIRsmith{
"resourceType": "Bundle",
"id": "bundle-drug-substance-specification-pq-ex1",
"meta": {
"profile": [
"http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Bundle-drug-substance-specification-pq"
]
},
"type": "collection",
"entry": [
{
"fullUrl": "urn:uuid:bf6b038b-1334-3dd4-a552-65c169e2265a",
"resource": {
"resourceType": "PlanDefinition",
"id": "specificationProtocol",
"text": {
"status": "generated",
"div": "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"PlanDefinition_specificationProtocol\"> </a><p><b>Generated Narrative: PlanDefinition</b><a name=\"specificationProtocol\"> </a><a name=\"hcspecificationProtocol\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource PlanDefinition "specificationProtocol" </p></div><p><b>url</b>: <code>http://example-server.com/fhir/PlanDefinition/bf6b038b-1334-3dd4-a552-65c169e2265a</code></p><p><b>title</b>: SPECIFICATION FOR DRUG SUBSTANCE</p><p><b>status</b>: active</p><p><b>subject</b>: See on this page: SubstanceDefinition/03d68d1c-162c-8b6e-70f9-647b0ea97adb</p><p><b>description</b>: Narrative description of specifications</p><blockquote><p><b>action</b></p><p><b>title</b>: Specification for Drug Substance</p><p><b>code</b>: Overall set of actions <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p><h3>Actions</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Definition[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Test <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td><td><a href=\"http://example-server.com/fhir/ObservationDefinition/52176085-1f30-0c67-9ad7-523c486c82c9\">http://example-server.com/fhir/ObservationDefinition/52176085-1f30-0c67-9ad7-523c486c82c9</a></td></tr><tr><td style=\"display: none\">*</td><td>Test <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td><td><a href=\"http://example-server.com/fhir/ObservationDefinition/b50d892c-8980-0774-39d4-d449732873a3\">http://example-server.com/fhir/ObservationDefinition/b50d892c-8980-0774-39d4-d449732873a3</a></td></tr><tr><td style=\"display: none\">*</td><td>Test <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td><td><a href=\"http://example-server.com/fhir/ObservationDefinition/d460b561-110c-7eb6-5d69-788abcca391a\">http://example-server.com/fhir/ObservationDefinition/d460b561-110c-7eb6-5d69-788abcca391a</a></td></tr><tr><td style=\"display: none\">*</td><td>Test <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td><td><a href=\"http://example-server.com/fhir/ObservationDefinition/006a9f7b-91ca-5601-38ef-a3dd26ad7121\">http://example-server.com/fhir/ObservationDefinition/006a9f7b-91ca-5601-38ef-a3dd26ad7121</a></td></tr><tr><td style=\"display: none\">*</td><td>Test <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td><td><a href=\"http://example-server.com/fhir/ObservationDefinition/c59deb1b-835c-1be5-4e08-95dea3ae1a17\">http://example-server.com/fhir/ObservationDefinition/c59deb1b-835c-1be5-4e08-95dea3ae1a17</a></td></tr><tr><td style=\"display: none\">*</td><td>Test <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td><td><a href=\"http://example-server.com/fhir/ObservationDefinition/18e20bae-1a24-202d-11d7-5f354c785e4d\">http://example-server.com/fhir/ObservationDefinition/18e20bae-1a24-202d-11d7-5f354c785e4d</a></td></tr><tr><td style=\"display: none\">*</td><td>Test <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td><td><a href=\"http://example-server.com/fhir/ObservationDefinition/22544fa4-0fa2-1d5a-253d-a1fbe8fd61ce\">http://example-server.com/fhir/ObservationDefinition/22544fa4-0fa2-1d5a-253d-a1fbe8fd61ce</a></td></tr><tr><td style=\"display: none\">*</td><td>Test <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td><td><a href=\"http://example-server.com/fhir/ObservationDefinition/b4f736ff-1bbf-6923-4d5c-85d262285d7d\">http://example-server.com/fhir/ObservationDefinition/b4f736ff-1bbf-6923-4d5c-85d262285d7d</a></td></tr><tr><td style=\"display: none\">*</td><td>Test <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td><td><a href=\"http://example-server.com/fhir/ObservationDefinition/233865df-2a71-528d-756c-85f36bd6685f\">http://example-server.com/fhir/ObservationDefinition/233865df-2a71-528d-756c-85f36bd6685f</a></td></tr></table></blockquote></div>"
},
"url": "http://example-server.com/fhir/PlanDefinition/bf6b038b-1334-3dd4-a552-65c169e2265a",
"title": "SPECIFICATION FOR DRUG SUBSTANCE",
"status": "active",
"subjectReference": {
"reference": "SubstanceDefinition/03d68d1c-162c-8b6e-70f9-647b0ea97adb"
},
"description": "Narrative description of specifications",
"action": [
{
"title": "Specification for Drug Substance",
"code": {
"text": "Overall set of actions"
},
"action": [
{
"code": {
"text": "Test"
},
"definitionCanonical": "http://example-server.com/fhir/ObservationDefinition/52176085-1f30-0c67-9ad7-523c486c82c9"
},
{
"code": {
"text": "Test"
},
"definitionCanonical": "http://example-server.com/fhir/ObservationDefinition/b50d892c-8980-0774-39d4-d449732873a3"
},
{
"code": {
"text": "Test"
},
"definitionCanonical": "http://example-server.com/fhir/ObservationDefinition/d460b561-110c-7eb6-5d69-788abcca391a"
},
{
"code": {
"text": "Test"
},
"definitionCanonical": "http://example-server.com/fhir/ObservationDefinition/006a9f7b-91ca-5601-38ef-a3dd26ad7121"
},
{
"code": {
"text": "Test"
},
"definitionCanonical": "http://example-server.com/fhir/ObservationDefinition/c59deb1b-835c-1be5-4e08-95dea3ae1a17"
},
{
"code": {
"text": "Test"
},
"definitionCanonical": "http://example-server.com/fhir/ObservationDefinition/18e20bae-1a24-202d-11d7-5f354c785e4d"
},
{
"code": {
"text": "Test"
},
"definitionCanonical": "http://example-server.com/fhir/ObservationDefinition/22544fa4-0fa2-1d5a-253d-a1fbe8fd61ce"
},
{
"code": {
"text": "Test"
},
"definitionCanonical": "http://example-server.com/fhir/ObservationDefinition/b4f736ff-1bbf-6923-4d5c-85d262285d7d"
},
{
"code": {
"text": "Test"
},
"definitionCanonical": "http://example-server.com/fhir/ObservationDefinition/233865df-2a71-528d-756c-85f36bd6685f"
}
]
}
]
}
},
{
"fullUrl": "urn:uuid:52176085-1f30-0c67-9ad7-523c486c82c9",
"resource": {
"resourceType": "ObservationDefinition",
"id": "52176085-1f30-0c67-9ad7-523c486c82c9",
"text": {
"status": "generated",
"div": "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"ObservationDefinition_52176085-1f30-0c67-9ad7-523c486c82c9\"> </a><p><b>Generated Narrative: ObservationDefinition</b><a name=\"52176085-1f30-0c67-9ad7-523c486c82c9\"> </a><a name=\"hc52176085-1f30-0c67-9ad7-523c486c82c9\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource ObservationDefinition "52176085-1f30-0c67-9ad7-523c486c82c9" </p></div><p><b>url</b>: <code>http://example-server.com/fhir/ObservationDefinition/52176085-1f30-0c67-9ad7-523c486c82c9</code></p><p><b>title</b>: Description</p><p><b>status</b>: active</p><p><b>code</b>: Description <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#DESC)</span></p><p><b>method</b>: Visual inspection <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p><h3>QualifiedValues</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Extension</b></td></tr><tr><td style=\"display: none\">*</td><td/></tr></table></div>"
},
"url": "http://example-server.com/fhir/ObservationDefinition/52176085-1f30-0c67-9ad7-523c486c82c9",
"title": "Description",
"status": "active",
"code": {
"coding": [
{
"system": "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
"code": "DESC",
"display": "Description"
}
],
"text": "Description"
},
"method": {
"text": "Visual inspection"
},
"qualifiedValue": [
{
"extension": [
{
"url": "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-qualified-value-text-pq",
"valueString": "A white to brown powder"
}
]
}
]
}
},
{
"fullUrl": "urn:uuid:b50d892c-8980-0774-39d4-d449732873a3",
"resource": {
"resourceType": "ObservationDefinition",
"id": "b50d892c-8980-0774-39d4-d449732873a3",
"text": {
"status": "generated",
"div": "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"ObservationDefinition_b50d892c-8980-0774-39d4-d449732873a3\"> </a><p><b>Generated Narrative: ObservationDefinition</b><a name=\"b50d892c-8980-0774-39d4-d449732873a3\"> </a><a name=\"hcb50d892c-8980-0774-39d4-d449732873a3\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource ObservationDefinition "b50d892c-8980-0774-39d4-d449732873a3" </p></div><p><b>url</b>: <code>http://example-server.com/fhir/ObservationDefinition/b50d892c-8980-0774-39d4-d449732873a3</code></p><p><b>title</b>: Identification</p><p><b>status</b>: active</p><p><b>code</b>: Identification <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#IDT)</span></p><p><b>method</b>: Identification by IR spectroscopy Identification by HPLC <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p><h3>QualifiedValues</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Extension</b></td></tr><tr><td style=\"display: none\">*</td><td/></tr></table></div>"
},
"url": "http://example-server.com/fhir/ObservationDefinition/b50d892c-8980-0774-39d4-d449732873a3",
"title": "Identification",
"status": "active",
"code": {
"coding": [
{
"system": "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
"code": "IDT",
"display": "Identification"
}
],
"text": "Identification"
},
"method": {
"text": "Identification by IR spectroscopy Identification by HPLC"
},
"qualifiedValue": [
{
"extension": [
{
"url": "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-qualified-value-text-pq",
"valueString": "Conforms with reference"
}
]
}
]
}
},
{
"fullUrl": "urn:uuid:d460b561-110c-7eb6-5d69-788abcca391a",
"resource": {
"resourceType": "ObservationDefinition",
"id": "d460b561-110c-7eb6-5d69-788abcca391a",
"text": {
"status": "generated",
"div": "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"ObservationDefinition_d460b561-110c-7eb6-5d69-788abcca391a\"> </a><p><b>Generated Narrative: ObservationDefinition</b><a name=\"d460b561-110c-7eb6-5d69-788abcca391a\"> </a><a name=\"hcd460b561-110c-7eb6-5d69-788abcca391a\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource ObservationDefinition "d460b561-110c-7eb6-5d69-788abcca391a" </p></div><p><b>url</b>: <code>http://example-server.com/fhir/ObservationDefinition/d460b561-110c-7eb6-5d69-788abcca391a</code></p><p><b>title</b>: Assay</p><p><b>status</b>: active</p><p><b>code</b>: Assay <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#ASSAY)</span></p><p><b>method</b>: Assay by LC <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p><h3>QualifiedValues</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Range</b></td></tr><tr><td style=\"display: none\">*</td><td>98-102 % w/w</td></tr></table></div>"
},
"url": "http://example-server.com/fhir/ObservationDefinition/d460b561-110c-7eb6-5d69-788abcca391a",
"title": "Assay",
"status": "active",
"code": {
"coding": [
{
"system": "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
"code": "ASSAY",
"display": "Assay"
}
],
"text": "Assay"
},
"method": {
"text": "Assay by LC"
},
"qualifiedValue": [
{
"range": {
"low": {
"value": 98,
"unit": "% w/w",
"system": "http://unitsofmeasure.org",
"code": "%"
},
"high": {
"value": 102,
"unit": "% w/w",
"system": "http://unitsofmeasure.org",
"code": "%"
}
}
}
]
}
},
{
"fullUrl": "urn:uuid:006a9f7b-91ca-5601-38ef-a3dd26ad7121",
"resource": {
"resourceType": "ObservationDefinition",
"id": "006a9f7b-91ca-5601-38ef-a3dd26ad7121",
"text": {
"status": "generated",
"div": "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"ObservationDefinition_006a9f7b-91ca-5601-38ef-a3dd26ad7121\"> </a><p><b>Generated Narrative: ObservationDefinition</b><a name=\"006a9f7b-91ca-5601-38ef-a3dd26ad7121\"> </a><a name=\"hc006a9f7b-91ca-5601-38ef-a3dd26ad7121\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource ObservationDefinition "006a9f7b-91ca-5601-38ef-a3dd26ad7121" </p></div><p><b>url</b>: <code>http://example-server.com/fhir/ObservationDefinition/006a9f7b-91ca-5601-38ef-a3dd26ad7121</code></p><p><b>title</b>: Drug Substance Related Organic impurities</p><p><b>status</b>: active</p><p><b>code</b>: Drug Substance Related Organic impurities <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#DGP-s)</span></p><p><b>method</b>: Organic impurities by LC <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p><blockquote><p><b>qualifiedValue</b></p><p><b>appliesTo</b>: Impurity 1 <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p><p><b>range</b>: ?-0.5</p></blockquote><blockquote><p><b>qualifiedValue</b></p><p><b>appliesTo</b>: Impurity 2 <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p><p><b>range</b>: ?-0.5</p></blockquote><blockquote><p><b>qualifiedValue</b></p><p><b>appliesTo</b>: Any individual unspecified impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p><p><b>range</b>: ?-0.10</p></blockquote><blockquote><p><b>qualifiedValue</b></p><p><b>appliesTo</b>: Total impurities <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p><p><b>range</b>: ?-2.0</p></blockquote><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td></tr><tr><td style=\"display: none\">*</td><td>Impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#IMP)</span></td></tr></table></div>"
},
"url": "http://example-server.com/fhir/ObservationDefinition/006a9f7b-91ca-5601-38ef-a3dd26ad7121",
"title": "Drug Substance Related Organic impurities",
"status": "active",
"code": {
"coding": [
{
"system": "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
"code": "DGP-s",
"display": "Drug Substance Related Organic impurities"
}
]
},
"method": {
"text": "Organic impurities by LC"
},
"qualifiedValue": [
{
"appliesTo": [
{
"text": "Impurity 1"
}
],
"range": {
"high": {
"value": 0.5,
"unit": "% w/w"
}
}
},
{
"appliesTo": [
{
"text": "Impurity 2"
}
],
"range": {
"high": {
"value": 0.5,
"unit": "% w/w"
}
}
},
{
"appliesTo": [
{
"text": "Any individual unspecified impurity"
}
],
"range": {
"high": {
"value": 0.1,
"unit": "% w/w"
}
}
},
{
"appliesTo": [
{
"text": "Total impurities"
}
],
"range": {
"high": {
"value": 2,
"unit": "% w/w"
}
}
}
],
"component": [
{
"code": {
"coding": [
{
"system": "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
"code": "IMP",
"display": "Impurity"
}
]
}
}
]
}
},
{
"fullUrl": "urn:uuid:c59deb1b-835c-1be5-4e08-95dea3ae1a17",
"resource": {
"resourceType": "ObservationDefinition",
"id": "c59deb1b-835c-1be5-4e08-95dea3ae1a17",
"text": {
"status": "generated",
"div": "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"ObservationDefinition_c59deb1b-835c-1be5-4e08-95dea3ae1a17\"> </a><p><b>Generated Narrative: ObservationDefinition</b><a name=\"c59deb1b-835c-1be5-4e08-95dea3ae1a17\"> </a><a name=\"hcc59deb1b-835c-1be5-4e08-95dea3ae1a17\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource ObservationDefinition "c59deb1b-835c-1be5-4e08-95dea3ae1a17" </p></div><p><b>url</b>: <code>http://example-server.com/fhir/ObservationDefinition/c59deb1b-835c-1be5-4e08-95dea3ae1a17</code></p><p><b>title</b>: Mutagenic impurities</p><p><b>status</b>: active</p><p><b>code</b>: Mutagenic impurities <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#MUT)</span></p><p><b>method</b>: Impurity 5 content by LC-MS <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p><h3>QualifiedValues</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>AppliesTo</b></td><td><b>Range</b></td></tr><tr><td style=\"display: none\">*</td><td>Impurity - Mutagenic <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td><td>?-50</td></tr></table><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td></tr><tr><td style=\"display: none\">*</td><td>Impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#IMP)</span></td></tr></table></div>"
},
"url": "http://example-server.com/fhir/ObservationDefinition/c59deb1b-835c-1be5-4e08-95dea3ae1a17",
"title": "Mutagenic impurities",
"status": "active",
"code": {
"coding": [
{
"system": "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
"code": "MUT",
"display": "Mutagenic impurities"
}
]
},
"method": {
"text": "Impurity 5 content by LC-MS"
},
"qualifiedValue": [
{
"appliesTo": [
{
"text": "Impurity - Mutagenic"
}
],
"range": {
"high": {
"value": 50,
"unit": "ppm",
"system": "http://unitsofmeasure.org",
"code": "[ppm]"
}
}
}
],
"component": [
{
"code": {
"coding": [
{
"system": "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
"code": "IMP",
"display": "Impurity"
}
]
}
}
]
}
},
{
"fullUrl": "urn:uuid:18e20bae-1a24-202d-11d7-5f354c785e4d",
"resource": {
"resourceType": "ObservationDefinition",
"id": "18e20bae-1a24-202d-11d7-5f354c785e4d",
"text": {
"status": "generated",
"div": "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"ObservationDefinition_18e20bae-1a24-202d-11d7-5f354c785e4d\"> </a><p><b>Generated Narrative: ObservationDefinition</b><a name=\"18e20bae-1a24-202d-11d7-5f354c785e4d\"> </a><a name=\"hc18e20bae-1a24-202d-11d7-5f354c785e4d\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource ObservationDefinition "18e20bae-1a24-202d-11d7-5f354c785e4d" </p></div><p><b>url</b>: <code>http://example-server.com/fhir/ObservationDefinition/18e20bae-1a24-202d-11d7-5f354c785e4d</code></p><p><b>title</b>: Enantiomeric purity</p><p><b>status</b>: active</p><p><b>code</b>: Enantiomeric purity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#enantiomeric-purity)</span></p><p><b>method</b>: Enantiomeric purity by LC <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p><h3>QualifiedValues</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Range</b></td></tr><tr><td style=\"display: none\">*</td><td>99.6-? %</td></tr></table></div>"
},
"url": "http://example-server.com/fhir/ObservationDefinition/18e20bae-1a24-202d-11d7-5f354c785e4d",
"title": "Enantiomeric purity",
"status": "active",
"code": {
"coding": [
{
"system": "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
"code": "enantiomeric-purity",
"display": "Enantiomeric purity"
}
],
"text": "Enantiomeric purity"
},
"method": {
"text": "Enantiomeric purity by LC"
},
"qualifiedValue": [
{
"range": {
"low": {
"value": 99.6,
"unit": "%",
"system": "http://unitsofmeasure.org",
"code": "%"
}
}
}
]
}
},
{
"fullUrl": "urn:uuid:22544fa4-0fa2-1d5a-253d-a1fbe8fd61ce",
"resource": {
"resourceType": "ObservationDefinition",
"id": "22544fa4-0fa2-1d5a-253d-a1fbe8fd61ce",
"text": {
"status": "generated",
"div": "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"ObservationDefinition_22544fa4-0fa2-1d5a-253d-a1fbe8fd61ce\"> </a><p><b>Generated Narrative: ObservationDefinition</b><a name=\"22544fa4-0fa2-1d5a-253d-a1fbe8fd61ce\"> </a><a name=\"hc22544fa4-0fa2-1d5a-253d-a1fbe8fd61ce\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource ObservationDefinition "22544fa4-0fa2-1d5a-253d-a1fbe8fd61ce" </p></div><p><b>url</b>: <code>http://example-server.com/fhir/ObservationDefinition/22544fa4-0fa2-1d5a-253d-a1fbe8fd61ce</code></p><p><b>title</b>: Residual solvents</p><p><b>status</b>: active</p><p><b>code</b>: Residual solvents <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#SOL)</span></p><p><b>method</b>: Residual solvents by headspace GC <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p><blockquote><p><b>qualifiedValue</b></p><p><b>appliesTo</b>: Solvent 1 <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p><p><b>range</b>: ?-0.1</p></blockquote><blockquote><p><b>qualifiedValue</b></p><p><b>appliesTo</b>: Solvent 2 <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p><p><b>range</b>: ?-2.0</p></blockquote><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td></tr><tr><td style=\"display: none\">*</td><td>Solvent <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#SOLV)</span></td></tr></table></div>"
},
"url": "http://example-server.com/fhir/ObservationDefinition/22544fa4-0fa2-1d5a-253d-a1fbe8fd61ce",
"title": "Residual solvents",
"status": "active",
"code": {
"coding": [
{
"system": "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
"code": "SOL",
"display": "Residual solvents"
}
]
},
"method": {
"text": "Residual solvents by headspace GC"
},
"qualifiedValue": [
{
"appliesTo": [
{
"text": "Solvent 1"
}
],
"range": {
"high": {
"value": 0.1,
"unit": "% w/w"
}
}
},
{
"appliesTo": [
{
"text": "Solvent 2"
}
],
"range": {
"high": {
"value": 2,
"unit": "% w/w"
}
}
}
],
"component": [
{
"code": {
"coding": [
{
"system": "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
"code": "SOLV",
"display": "Solvent"
}
]
}
}
]
}
},
{
"fullUrl": "urn:uuid:b4f736ff-1bbf-6923-4d5c-85d262285d7d",
"resource": {
"resourceType": "ObservationDefinition",
"id": "b4f736ff-1bbf-6923-4d5c-85d262285d7d",
"text": {
"status": "generated",
"div": "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"ObservationDefinition_b4f736ff-1bbf-6923-4d5c-85d262285d7d\"> </a><p><b>Generated Narrative: ObservationDefinition</b><a name=\"b4f736ff-1bbf-6923-4d5c-85d262285d7d\"> </a><a name=\"hcb4f736ff-1bbf-6923-4d5c-85d262285d7d\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource ObservationDefinition "b4f736ff-1bbf-6923-4d5c-85d262285d7d" </p></div><p><b>url</b>: <code>http://example-server.com/fhir/ObservationDefinition/b4f736ff-1bbf-6923-4d5c-85d262285d7d</code></p><p><b>title</b>: Water Content</p><p><b>status</b>: active</p><p><b>code</b>: Water Content <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#WaterContent)</span></p><p><b>method</b>: USP Karl Fischer titration <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p><h3>QualifiedValues</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Range</b></td></tr><tr><td style=\"display: none\">*</td><td>?-1.0</td></tr></table></div>"
},
"url": "http://example-server.com/fhir/ObservationDefinition/b4f736ff-1bbf-6923-4d5c-85d262285d7d",
"title": "Water Content",
"status": "active",
"code": {
"coding": [
{
"system": "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
"code": "WaterContent",
"display": "Water Content"
}
],
"text": "Water Content"
},
"method": {
"text": "USP Karl Fischer titration"
},
"qualifiedValue": [
{
"range": {
"high": {
"value": 1,
"unit": "% w/w"
}
}
}
]
}
},
{
"fullUrl": "urn:uuid:233865df-2a71-528d-756c-85f36bd6685f",
"resource": {
"resourceType": "ObservationDefinition",
"id": "233865df-2a71-528d-756c-85f36bd6685f",
"text": {
"status": "generated",
"div": "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"ObservationDefinition_233865df-2a71-528d-756c-85f36bd6685f\"> </a><p><b>Generated Narrative: ObservationDefinition</b><a name=\"233865df-2a71-528d-756c-85f36bd6685f\"> </a><a name=\"hc233865df-2a71-528d-756c-85f36bd6685f\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource ObservationDefinition "233865df-2a71-528d-756c-85f36bd6685f" </p></div><p><b>url</b>: <code>http://example-server.com/fhir/ObservationDefinition/233865df-2a71-528d-756c-85f36bd6685f</code></p><p><b>title</b>: Particle size distribution</p><p><b>status</b>: active</p><p><b>code</b>: Particle size distribution <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#particle-size-distribution)</span></p><p><b>method</b>: Laser diffraction <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p><blockquote><p><b>qualifiedValue</b></p><p><b>appliesTo</b>: D(v,0.9) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p><p><b>range</b>: ?-319</p></blockquote><blockquote><p><b>qualifiedValue</b></p><p><b>appliesTo</b>: D(v,0.5) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p><p><b>range</b>: ?-145</p></blockquote><blockquote><p><b>qualifiedValue</b></p><p><b>appliesTo</b>: D(v,0.1) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p><p><b>range</b>: ?-20</p></blockquote><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td></tr><tr><td style=\"display: none\">*</td><td>Particle size <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#particle-size)</span></td></tr></table></div>"
},
"url": "http://example-server.com/fhir/ObservationDefinition/233865df-2a71-528d-756c-85f36bd6685f",
"title": "Particle size distribution",
"status": "active",
"code": {
"coding": [
{
"system": "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
"code": "particle-size-distribution",
"display": "Particle size distribution"
}
]
},
"method": {
"text": "Laser diffraction"
},
"qualifiedValue": [
{
"appliesTo": [
{
"text": "D(v,0.9)"
}
],
"range": {
"high": {
"value": 319,
"unit": "µm",
"system": "http://unitsofmeasure.org",
"code": "um"
}
}
},
{
"appliesTo": [
{
"text": "D(v,0.5)"
}
],
"range": {
"high": {
"value": 145,
"unit": "µm",
"system": "http://unitsofmeasure.org",
"code": "um"
}
}
},
{
"appliesTo": [
{
"text": "D(v,0.1)"
}
],
"range": {
"high": {
"value": 20,
"unit": "µm",
"system": "http://unitsofmeasure.org",
"code": "um"
}
}
}
],
"component": [
{
"code": {
"coding": [
{
"system": "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
"code": "particle-size",
"display": "Particle size"
}
]
}
}
]
}
},
{
"fullUrl": "urn:uuid:03d68d1c-162c-8b6e-70f9-647b0ea97adb",
"resource": {
"resourceType": "SubstanceDefinition",
"id": "03d68d1c-162c-8b6e-70f9-647b0ea97adb",
"text": {
"status": "generated",
"div": "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"SubstanceDefinition_03d68d1c-162c-8b6e-70f9-647b0ea97adb\"> </a><p><b>Generated Narrative: SubstanceDefinition</b><a name=\"03d68d1c-162c-8b6e-70f9-647b0ea97adb\"> </a><a name=\"hc03d68d1c-162c-8b6e-70f9-647b0ea97adb\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource SubstanceDefinition "03d68d1c-162c-8b6e-70f9-647b0ea97adb" </p></div><p><b>manufacturer</b>: See on this page: Organization/062bf235-44e2-55c4-9213-bbe5e12d5620</p><h3>Names</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Name</b></td></tr><tr><td style=\"display: none\">*</td><td>Stelbatolol</td></tr></table></div>"
},
"manufacturer": [
{
"reference": "Organization/062bf235-44e2-55c4-9213-bbe5e12d5620"
}
],
"name": [
{
"name": "Stelbatolol"
}
]
}
},
{
"fullUrl": "urn:uuid:062bf235-44e2-55c4-9213-bbe5e12d5620",
"resource": {
"resourceType": "Organization",
"id": "062bf235-44e2-55c4-9213-bbe5e12d5620",
"text": {
"status": "generated",
"div": "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Organization_062bf235-44e2-55c4-9213-bbe5e12d5620\"> </a><p><b>Generated Narrative: Organization</b><a name=\"062bf235-44e2-55c4-9213-bbe5e12d5620\"> </a><a name=\"hc062bf235-44e2-55c4-9213-bbe5e12d5620\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Organization "062bf235-44e2-55c4-9213-bbe5e12d5620" </p></div><p><b>identifier</b>: <code>urn:oid:2.16.840.1.113883.4.82</code>/3003040516</p><p><b>active</b>: true</p><p><b>type</b>: Drug Substance Manufacture <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-pharmaceutical-organization-type.html\">Pharmaceutical Organization Type Codes</a>#drug-substance-manufacture)</span></p><p><b>name</b>: AAA Molybdenum Products, Inc.</p><h3>Contacts</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Address</b></td></tr><tr><td style=\"display: none\">*</td><td>7233 W 116th Pl Ste C Broomfield Colorado 80020 USA </td></tr></table></div>"
},
"identifier": [
{
"system": "urn:oid:2.16.840.1.113883.4.82",
"value": "3003040516"
}
],
"active": true,
"type": [
{
"coding": [
{
"system": "http://terminology.hl7.org/CodeSystem/pharmaceutical-organization-type",
"code": "drug-substance-manufacture",
"display": "Drug Substance Manufacture"
}
]
}
],
"name": "AAA Molybdenum Products, Inc.",
"contact": [
{
"address": {
"line": [
"7233 W 116th Pl",
"Ste C"
],
"city": "Broomfield",
"state": "Colorado",
"postalCode": "80020",
"country": "USA"
}
}
]
}
}
]
}