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Packagehl7.fhir.uv.order-catalog
Resource TypeClinicalUseDefinition
IdClinicalUseDefinition-example-interaction.json
FHIR VersionR5

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Narrative

Note: links and images are rebased to the (stated) source

Drug interaction: Clarithromycin and Warfarin - increased anticoagulant effect


Source1

{
  "resourceType": "ClinicalUseDefinition",
  "id": "example-interaction",
  "meta": {
    "profile": [
      "http://hl7.org/fhir/uv/order-catalog/StructureDefinition/InteractionDefinition"
    ]
  },
  "language": "en-US",
  "text": {
    "status": "generated",
    "div": "<!-- snip (see above) -->"
  },
  "type": "interaction",
  "interaction": {
    "interactant": [
      {
        "itemCodeableConcept": {
          "coding": [
            {
              "system": "http://snomed.info/sct",
              "code": "387487009",
              "display": "Clarithromycin"
            }
          ]
        }
      },
      {
        "itemCodeableConcept": {
          "coding": [
            {
              "system": "http://snomed.info/sct",
              "code": "372756006",
              "display": "Warfarin"
            }
          ]
        }
      }
    ],
    "type": {
      "coding": [
        {
          "system": "http://hl7.org/fhir/interaction-type",
          "code": "drug-drug",
          "display": "drug to drug interaction"
        }
      ]
    },
    "effect": {
      "concept": {
        "coding": [
          {
            "system": "http://snomed.info/sct",
            "code": "419511003",
            "display": "Propensity to adverse reactions to drug"
          }
        ],
        "text": "Increased anticoagulant effect and risk of bleeding"
      }
    }
  }
}