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Packagehl7.fhir.uv.ichom-breast-cancer.r4b
Resource TypeBundle
IdBundle-DebugBundleClinical-01-Baseline.json
FHIR VersionR4B

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Source1

{
  "resourceType": "Bundle",
  "id": "DebugBundleClinical-01-Baseline",
  "type": "transaction",
  "entry": [
    {
      "resource": {
        "resourceType": "ValueSet",
        "id": "LateralityVS",
        "text": {
          "status": "generated",
          "div": "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p><b>Generated Narrative: ValueSet</b><a name=\"LateralityVS\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource ValueSet &quot;LateralityVS&quot; </p></div><p><b>url</b>: <code>http://hl7.org/fhir/uv/ichom-breast-cancer/ValueSet/LateralityVS</code></p><p><b>version</b>: 5.1</p><p><b>name</b>: LateralityVS</p><p><b>title</b>: Laterality of breast cancer ValueSet</p><p><b>status</b>: active</p><p><b>experimental</b>: false</p><p><b>publisher</b>: ICHOM</p><p><b>description</b>: Valueset of the laterality of breast cancer</p><p><b>copyright</b>: This value set includes content from SNOMED CT, which is copyright © 2002+ International Health Terminology Standards Development Organisation (IHTSDO), and distributed by agreement between IHTSDO and HL7. Implementer use of SNOMED CT is not covered by this agreement</p><blockquote><p><b>compose</b></p><blockquote><p><b>include</b></p><p><b>system</b>: <a href=\"http://hl7.org/fhir/R4/codesystem-snomedct.html\">SNOMED CT (all versions)</a></p><blockquote><p><b>concept</b></p><p><b>code</b>: 80248007</p><p><b>display</b>: Left breast structure</p></blockquote><blockquote><p><b>concept</b></p><p><b>code</b>: 73056007</p><p><b>display</b>: Right breast structure</p></blockquote><blockquote><p><b>concept</b></p><p><b>code</b>: 63762007</p><p><b>display</b>: Both breasts</p></blockquote></blockquote></blockquote></div>"
        },
        "url": "http://hl7.org/fhir/uv/ichom-breast-cancer/ValueSet/LateralityVS",
        "version": "5.1",
        "name": "LateralityVS",
        "title": "Laterality of breast cancer ValueSet",
        "status": "active",
        "experimental": false,
        "publisher": "ICHOM",
        "description": "Valueset of the laterality of breast cancer",
        "copyright": "This value set includes content from SNOMED CT, which is copyright © 2002+ International Health Terminology Standards Development Organisation (IHTSDO), and distributed by agreement between IHTSDO and HL7. Implementer use of SNOMED CT is not covered by this agreement",
        "compose": {
          "include": [
            {
              "system": "http://snomed.info/sct",
              "concept": [
                {
                  "code": "80248007",
                  "display": "Left breast structure"
                },
                {
                  "code": "73056007",
                  "display": "Right breast structure"
                },
                {
                  "code": "63762007",
                  "display": "Both breasts"
                }
              ]
            }
          ]
        }
      },
      "request": {
        "method": "PUT",
        "url": "ValueSet/LateralityVS"
      }
    },
    {
      "resource": {
        "resourceType": "ValueSet",
        "id": "NoYesUnknownVS",
        "text": {
          "status": "generated",
          "div": "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p><b>Generated Narrative: ValueSet</b><a name=\"NoYesUnknownVS\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource ValueSet &quot;NoYesUnknownVS&quot; </p></div><p><b>url</b>: <code>http://hl7.org/fhir/uv/ichom-breast-cancer/ValueSet/NoYesUnknownVS</code></p><p><b>version</b>: 5.1</p><p><b>name</b>: NoYesUnknownVS</p><p><b>title</b>: Yes, No and Unknown Valueset</p><p><b>status</b>: active</p><p><b>experimental</b>: false</p><p><b>publisher</b>: ICHOM</p><p><b>description</b>: Valueset with yes, no and unknown answers</p><p><b>copyright</b>: Copyright HL7. Licensed under creative commons public domain</p><blockquote><p><b>compose</b></p><blockquote><p><b>include</b></p><p><b>system</b>: <a href=\"http://terminology.hl7.org/5.0.0/CodeSystem-v2-0532.html\">expandedYes-NoIndicator</a></p><blockquote><p><b>concept</b></p><p><b>code</b>: Y</p><p><b>display</b>: Yes</p></blockquote><blockquote><p><b>concept</b></p><p><b>code</b>: N</p><p><b>display</b>: No</p></blockquote><blockquote><p><b>concept</b></p><p><b>code</b>: UNK</p><p><b>display</b>: Unknown</p></blockquote></blockquote></blockquote></div>"
        },
        "url": "http://hl7.org/fhir/uv/ichom-breast-cancer/ValueSet/NoYesUnknownVS",
        "version": "5.1",
        "name": "NoYesUnknownVS",
        "title": "Yes, No and Unknown Valueset",
        "status": "active",
        "experimental": false,
        "publisher": "ICHOM",
        "description": "Valueset with yes, no and unknown answers",
        "copyright": "Copyright HL7. Licensed under creative commons public domain",
        "compose": {
          "include": [
            {
              "system": "http://terminology.hl7.org/CodeSystem/v2-0532",
              "concept": [
                {
                  "code": "Y",
                  "display": "Yes"
                },
                {
                  "code": "N",
                  "display": "No"
                },
                {
                  "code": "UNK",
                  "display": "Unknown"
                }
              ]
            }
          ]
        }
      },
      "request": {
        "method": "PUT",
        "url": "ValueSet/NoYesUnknownVS"
      }
    },
    {
      "resource": {
        "resourceType": "ValueSet",
        "id": "LateralityNewCancerVS",
        "text": {
          "status": "generated",
          "div": "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p><b>Generated Narrative: ValueSet</b><a name=\"LateralityNewCancerVS\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource ValueSet &quot;LateralityNewCancerVS&quot; </p></div><p><b>url</b>: <code>http://hl7.org/fhir/uv/ichom-breast-cancer/ValueSet/LateralityNewCancerVS</code></p><p><b>version</b>: 5.1</p><p><b>name</b>: LateralityNewCancerVS</p><p><b>title</b>: Laterality of new cancer ValueSet</p><p><b>status</b>: active</p><p><b>experimental</b>: false</p><p><b>publisher</b>: ICHOM</p><p><b>description</b>: Valueset of the laterality of new breast cancer</p><p><b>copyright</b>: This value set includes content from SNOMED CT, which is copyright © 2002+ International Health Terminology Standards Development Organisation (IHTSDO), and distributed by agreement between IHTSDO and HL7. Implementer use of SNOMED CT is not covered by this agreement</p><blockquote><p><b>compose</b></p><blockquote><p><b>include</b></p><p><b>system</b>: <a href=\"http://hl7.org/fhir/R4/codesystem-snomedct.html\">SNOMED CT (all versions)</a></p><blockquote><p><b>concept</b></p><p><b>code</b>: 255208005</p><p><b>display</b>: Ipsilateral</p></blockquote><blockquote><p><b>concept</b></p><p><b>code</b>: 255209002</p><p><b>display</b>: Contralateral</p></blockquote></blockquote></blockquote></div>"
        },
        "url": "http://hl7.org/fhir/uv/ichom-breast-cancer/ValueSet/LateralityNewCancerVS",
        "version": "5.1",
        "name": "LateralityNewCancerVS",
        "title": "Laterality of new cancer ValueSet",
        "status": "active",
        "experimental": false,
        "publisher": "ICHOM",
        "description": "Valueset of the laterality of new breast cancer",
        "copyright": "This value set includes content from SNOMED CT, which is copyright © 2002+ International Health Terminology Standards Development Organisation (IHTSDO), and distributed by agreement between IHTSDO and HL7. Implementer use of SNOMED CT is not covered by this agreement",
        "compose": {
          "include": [
            {
              "system": "http://snomed.info/sct",
              "concept": [
                {
                  "code": "255208005",
                  "display": "Ipsilateral"
                },
                {
                  "code": "255209002",
                  "display": "Contralateral"
                }
              ]
            }
          ]
        }
      },
      "request": {
        "method": "PUT",
        "url": "ValueSet/LateralityNewCancerVS"
      }
    },
    {
      "resource": {
        "resourceType": "ValueSet",
        "id": "HistologicalTypeVS",
        "text": {
          "status": "generated",
          "div": "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p><b>Generated Narrative: ValueSet</b><a name=\"HistologicalTypeVS\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource ValueSet &quot;HistologicalTypeVS&quot; </p></div><p><b>url</b>: <code>http://hl7.org/fhir/uv/ichom-breast-cancer/ValueSet/HistologicalTypeVS</code></p><p><b>version</b>: 5.1</p><p><b>name</b>: HistologicalTypeVS</p><p><b>title</b>: Histological type of the tumor ValueSet</p><p><b>status</b>: active</p><p><b>experimental</b>: false</p><p><b>publisher</b>: ICHOM</p><p><b>description</b>: Valueset of the histological types of tumors</p><p><b>copyright</b>: This value set includes content from SNOMED CT, which is copyright © 2002+ International Health Terminology Standards Development Organisation (IHTSDO), and distributed by agreement between IHTSDO and HL7. Implementer use of SNOMED CT is not covered by this agreement</p><blockquote><p><b>compose</b></p><blockquote><p><b>include</b></p><p><b>system</b>: <a href=\"http://hl7.org/fhir/R4/codesystem-snomedct.html\">SNOMED CT (all versions)</a></p><blockquote><p><b>concept</b></p><p><b>code</b>: 399935008</p><p><b>display</b>: Ductal carcinoma in situ - category</p></blockquote><blockquote><p><b>concept</b></p><p><b>code</b>: 373395001</p><p><b>display</b>: Invasive ductal carcinoma with an extensive intraductal component</p></blockquote><blockquote><p><b>concept</b></p><p><b>code</b>: 722524005</p><p><b>display</b>: Primary invasive pleomorphic lobular carcinoma of breast</p></blockquote></blockquote><blockquote><p><b>include</b></p><p><b>system</b>: <a href=\"http://terminology.hl7.org/5.0.0/CodeSystem-v3-NullFlavor.html\">NullFlavor</a></p><blockquote><p><b>concept</b></p><p><b>code</b>: OTH</p><p><b>display</b>: other</p></blockquote><blockquote><p><b>concept</b></p><p><b>code</b>: UNK</p><p><b>display</b>: unknown</p></blockquote></blockquote></blockquote></div>"
        },
        "url": "http://hl7.org/fhir/uv/ichom-breast-cancer/ValueSet/HistologicalTypeVS",
        "version": "5.1",
        "name": "HistologicalTypeVS",
        "title": "Histological type of the tumor ValueSet",
        "status": "active",
        "experimental": false,
        "publisher": "ICHOM",
        "description": "Valueset of the histological types of tumors",
        "copyright": "This value set includes content from SNOMED CT, which is copyright © 2002+ International Health Terminology Standards Development Organisation (IHTSDO), and distributed by agreement between IHTSDO and HL7. Implementer use of SNOMED CT is not covered by this agreement",
        "compose": {
          "include": [
            {
              "system": "http://snomed.info/sct",
              "concept": [
                {
                  "code": "399935008",
                  "display": "Ductal carcinoma in situ - category"
                },
                {
                  "code": "373395001",
                  "display": "Invasive ductal carcinoma with an extensive intraductal component"
                },
                {
                  "code": "722524005",
                  "display": "Primary invasive pleomorphic lobular carcinoma of breast"
                }
              ]
            },
            {
              "system": "http://terminology.hl7.org/CodeSystem/v3-NullFlavor",
              "concept": [
                {
                  "code": "OTH",
                  "display": "other"
                },
                {
                  "code": "UNK",
                  "display": "unknown"
                }
              ]
            }
          ]
        }
      },
      "request": {
        "method": "PUT",
        "url": "ValueSet/HistologicalTypeVS"
      }
    },
    {
      "resource": {
        "resourceType": "ValueSet",
        "id": "GermlineMutationVS",
        "text": {
          "status": "generated",
          "div": "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p><b>Generated Narrative: ValueSet</b><a name=\"GermlineMutationVS\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource ValueSet &quot;GermlineMutationVS&quot; </p></div><p><b>url</b>: <code>http://hl7.org/fhir/uv/ichom-breast-cancer/ValueSet/GermlineMutationVS</code></p><p><b>version</b>: 5.1</p><p><b>name</b>: GermlineMutationVS</p><p><b>title</b>: Germline Mutation ValueSet</p><p><b>status</b>: active</p><p><b>experimental</b>: false</p><p><b>publisher</b>: ICHOM</p><p><b>description</b>: Valueset of the genetic mutation predisposing breast cancer</p><p><b>copyright</b>: This value set includes content from SNOMED CT, which is copyright © 2002+ International Health Terminology Standards Development Organisation (IHTSDO), and distributed by agreement between IHTSDO and HL7. Implementer use of SNOMED CT is not covered by this agreement</p><blockquote><p><b>compose</b></p><blockquote><p><b>include</b></p><p><b>system</b>: <a href=\"http://hl7.org/fhir/R4/codesystem-snomedct.html\">SNOMED CT (all versions)</a></p><blockquote><p><b>concept</b></p><p><b>code</b>: 445180002</p><p><b>display</b>: Breast cancer genetic marker of susceptibility negative (finding)</p></blockquote><blockquote><p><b>concept</b></p><p><b>code</b>: 412734009</p><p><b>display</b>: BRCA1 gene mutation positive (finding)</p></blockquote><blockquote><p><b>concept</b></p><p><b>code</b>: 412738007</p><p><b>display</b>: BRCA2 gene mutation positive (finding)</p></blockquote><blockquote><p><b>concept</b></p><p><b>code</b>: 416237000</p><p><b>display</b>: Procedure not done</p></blockquote></blockquote><blockquote><p><b>include</b></p><p><b>system</b>: <a href=\"http://terminology.hl7.org/5.0.0/CodeSystem-v3-NullFlavor.html\">NullFlavor</a></p><h3>Concepts</h3><table class=\"grid\"><tr><td>-</td><td><b>Code</b></td><td><b>Display</b></td></tr><tr><td>*</td><td>OTH</td><td>other</td></tr></table></blockquote></blockquote></div>"
        },
        "url": "http://hl7.org/fhir/uv/ichom-breast-cancer/ValueSet/GermlineMutationVS",
        "version": "5.1",
        "name": "GermlineMutationVS",
        "title": "Germline Mutation ValueSet",
        "status": "active",
        "experimental": false,
        "publisher": "ICHOM",
        "description": "Valueset of the genetic mutation predisposing breast cancer",
        "copyright": "This value set includes content from SNOMED CT, which is copyright © 2002+ International Health Terminology Standards Development Organisation (IHTSDO), and distributed by agreement between IHTSDO and HL7. Implementer use of SNOMED CT is not covered by this agreement",
        "compose": {
          "include": [
            {
              "system": "http://snomed.info/sct",
              "concept": [
                {
                  "code": "445180002",
                  "display": "Breast cancer genetic marker of susceptibility negative (finding)"
                },
                {
                  "code": "412734009",
                  "display": "BRCA1 gene mutation positive (finding)"
                },
                {
                  "code": "412738007",
                  "display": "BRCA2 gene mutation positive (finding)"
                },
                {
                  "code": "416237000",
                  "display": "Procedure not done"
                }
              ]
            },
            {
              "system": "http://terminology.hl7.org/CodeSystem/v3-NullFlavor",
              "concept": [
                {
                  "code": "OTH",
                  "display": "other"
                }
              ]
            }
          ]
        }
      },
      "request": {
        "method": "PUT",
        "url": "ValueSet/GermlineMutationVS"
      }
    },
    {
      "resource": {
        "resourceType": "ValueSet",
        "id": "GradingVS",
        "text": {
          "status": "generated",
          "div": "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p><b>Generated Narrative: ValueSet</b><a name=\"GradingVS\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource ValueSet &quot;GradingVS&quot; </p></div><p><b>url</b>: <code>http://hl7.org/fhir/uv/ichom-breast-cancer/ValueSet/GradingVS</code></p><p><b>version</b>: 5.1</p><p><b>name</b>: GradingVS</p><p><b>title</b>: Grading of tumor ValueSet</p><p><b>status</b>: active</p><p><b>experimental</b>: false</p><p><b>publisher</b>: ICHOM</p><p><b>description</b>: Valueset of the grade of the tumor</p><p><b>copyright</b>: This value set includes content from SNOMED CT, which is copyright © 2002+ International Health Terminology Standards Development Organisation (IHTSDO), and distributed by agreement between IHTSDO and HL7. Implementer use of SNOMED CT is not covered by this agreement</p><blockquote><p><b>compose</b></p><blockquote><p><b>include</b></p><p><b>system</b>: <a href=\"http://hl7.org/fhir/R4/codesystem-snomedct.html\">SNOMED CT (all versions)</a></p><blockquote><p><b>concept</b></p><p><b>code</b>: 399415002</p><p><b>display</b>: Low grade histologic differentiation (finding)</p></blockquote><blockquote><p><b>concept</b></p><p><b>code</b>: 405986005</p><p><b>display</b>: Intermediate grade histologic differentiation (finding)</p></blockquote><blockquote><p><b>concept</b></p><p><b>code</b>: 399611001</p><p><b>display</b>: High grade histologic differentiation (finding)</p></blockquote></blockquote><blockquote><p><b>include</b></p><p><b>system</b>: <a href=\"http://terminology.hl7.org/5.0.0/CodeSystem-v3-NullFlavor.html\">NullFlavor</a></p><h3>Concepts</h3><table class=\"grid\"><tr><td>-</td><td><b>Code</b></td><td><b>Display</b></td></tr><tr><td>*</td><td>NI</td><td>No information</td></tr></table></blockquote></blockquote></div>"
        },
        "url": "http://hl7.org/fhir/uv/ichom-breast-cancer/ValueSet/GradingVS",
        "version": "5.1",
        "name": "GradingVS",
        "title": "Grading of tumor ValueSet",
        "status": "active",
        "experimental": false,
        "publisher": "ICHOM",
        "description": "Valueset of the grade of the tumor",
        "copyright": "This value set includes content from SNOMED CT, which is copyright © 2002+ International Health Terminology Standards Development Organisation (IHTSDO), and distributed by agreement between IHTSDO and HL7. Implementer use of SNOMED CT is not covered by this agreement",
        "compose": {
          "include": [
            {
              "system": "http://snomed.info/sct",
              "concept": [
                {
                  "code": "399415002",
                  "display": "Low grade histologic differentiation (finding)"
                },
                {
                  "code": "405986005",
                  "display": "Intermediate grade histologic differentiation (finding)"
                },
                {
                  "code": "399611001",
                  "display": "High grade histologic differentiation (finding)"
                }
              ]
            },
            {
              "system": "http://terminology.hl7.org/CodeSystem/v3-NullFlavor",
              "concept": [
                {
                  "code": "NI",
                  "display": "No information"
                }
              ]
            }
          ]
        }
      },
      "request": {
        "method": "PUT",
        "url": "ValueSet/GradingVS"
      }
    },
    {
      "resource": {
        "resourceType": "ValueSet",
        "id": "TNMPrimaryTumorVS",
        "text": {
          "status": "generated",
          "div": "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p><b>Generated Narrative: ValueSet</b><a name=\"TNMPrimaryTumorVS\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource ValueSet &quot;TNMPrimaryTumorVS&quot; </p></div><p><b>url</b>: <code>http://hl7.org/fhir/uv/ichom-breast-cancer/ValueSet/TNMPrimaryTumorVS</code></p><p><b>version</b>: 5.1</p><p><b>name</b>: TNMPrimaryTumorVS</p><p><b>title</b>: TNM Primary Tumor ValueSet</p><p><b>status</b>: active</p><p><b>experimental</b>: false</p><p><b>publisher</b>: ICHOM</p><p><b>description</b>: Valueset of the TNM stage for the T category, according to TNM staging rules</p><p><b>copyright</b>: This value set includes content from SNOMED CT, which is copyright © 2002+ International Health Terminology Standards Development Organisation (IHTSDO), and distributed by agreement between IHTSDO and HL7. Implementer use of SNOMED CT is not covered by this agreement</p><blockquote><p><b>compose</b></p><blockquote><p><b>include</b></p><p><b>system</b>: <a href=\"http://hl7.org/fhir/R4/codesystem-snomedct.html\">SNOMED CT (all versions)</a></p><blockquote><p><b>concept</b></p><p><b>code</b>: 1222604002</p><p><b>display</b>: American Joint Committee on Cancer cTX</p></blockquote><blockquote><p><b>concept</b></p><p><b>code</b>: 1228882005</p><p><b>display</b>: American Joint Committee on Cancer cT0</p></blockquote><blockquote><p><b>concept</b></p><p><b>code</b>: 1228885007</p><p><b>display</b>: American Joint Committee on Cancer cTis(DCIS)</p></blockquote><blockquote><p><b>concept</b></p><p><b>code</b>: 1228888009</p><p><b>display</b>: American Joint Committee on Cancer cTis(Paget)</p></blockquote><blockquote><p><b>concept</b></p><p><b>code</b>: 1228889001</p><p><b>display</b>: American Joint Committee on Cancer cT1</p></blockquote><blockquote><p><b>concept</b></p><p><b>code</b>: 1228929004</p><p><b>display</b>: American Joint Committee on Cancer cT2</p></blockquote><blockquote><p><b>concept</b></p><p><b>code</b>: 1228938002</p><p><b>display</b>: American Joint Committee on Cancer cT3</p></blockquote><blockquote><p><b>concept</b></p><p><b>code</b>: 1228944003</p><p><b>display</b>: American Joint Committee on Cancer cT4</p></blockquote><blockquote><p><b>concept</b></p><p><b>code</b>: 1228950008</p><p><b>display</b>: American Joint Committee on Cancer pTX</p></blockquote><blockquote><p><b>concept</b></p><p><b>code</b>: 1228951007</p><p><b>display</b>: American Joint Committee on Cancer pT0</p></blockquote><blockquote><p><b>concept</b></p><p><b>code</b>: 1228954004</p><p><b>display</b>: American Joint Committee on Cancer pTis(DCIS)</p></blockquote><blockquote><p><b>concept</b></p><p><b>code</b>: 1228956002</p><p><b>display</b>: American Joint Committee on Cancer pTis(Paget)</p></blockquote><blockquote><p><b>concept</b></p><p><b>code</b>: 1228957006</p><p><b>display</b>: American Joint Committee on Cancer pT1</p></blockquote><blockquote><p><b>concept</b></p><p><b>code</b>: 1229852009</p><p><b>display</b>: American Joint Committee on Cancer pT2</p></blockquote><blockquote><p><b>concept</b></p><p><b>code</b>: 1229859000</p><p><b>display</b>: American Joint Committee on Cancer pT3</p></blockquote><blockquote><p><b>concept</b></p><p><b>code</b>: 1229864001</p><p><b>display</b>: American Joint Committee on Cancer pT4</p></blockquote></blockquote><blockquote><p><b>include</b></p><p><b>system</b>: <a href=\"http://terminology.hl7.org/5.0.0/CodeSystem-v3-NullFlavor.html\">NullFlavor</a></p><h3>Concepts</h3><table class=\"grid\"><tr><td>-</td><td><b>Code</b></td><td><b>Display</b></td></tr><tr><td>*</td><td>UNK</td><td>unknown</td></tr></table></blockquote></blockquote></div>"
        },
        "url": "http://hl7.org/fhir/uv/ichom-breast-cancer/ValueSet/TNMPrimaryTumorVS",
        "version": "5.1",
        "name": "TNMPrimaryTumorVS",
        "title": "TNM Primary Tumor ValueSet",
        "status": "active",
        "experimental": false,
        "publisher": "ICHOM",
        "description": "Valueset of the TNM stage for the T category, according to TNM staging rules",
        "copyright": "This value set includes content from SNOMED CT, which is copyright © 2002+ International Health Terminology Standards Development Organisation (IHTSDO), and distributed by agreement between IHTSDO and HL7. Implementer use of SNOMED CT is not covered by this agreement",
        "compose": {
          "include": [
            {
              "system": "http://snomed.info/sct",
              "concept": [
                {
                  "code": "1222604002",
                  "display": "American Joint Committee on Cancer cTX"
                },
                {
                  "code": "1228882005",
                  "display": "American Joint Committee on Cancer cT0"
                },
                {
                  "code": "1228885007",
                  "display": "American Joint Committee on Cancer cTis(DCIS)"
                },
                {
                  "code": "1228888009",
                  "display": "American Joint Committee on Cancer cTis(Paget)"
                },
                {
                  "code": "1228889001",
                  "display": "American Joint Committee on Cancer cT1"
                },
                {
                  "code": "1228929004",
                  "display": "American Joint Committee on Cancer cT2"
                },
                {
                  "code": "1228938002",
                  "display": "American Joint Committee on Cancer cT3"
                },
                {
                  "code": "1228944003",
                  "display": "American Joint Committee on Cancer cT4"
                },
                {
                  "code": "1228950008",
                  "display": "American Joint Committee on Cancer pTX"
                },
                {
                  "code": "1228951007",
                  "display": "American Joint Committee on Cancer pT0"
                },
                {
                  "code": "1228954004",
                  "display": "American Joint Committee on Cancer pTis(DCIS)"
                },
                {
                  "code": "1228956002",
                  "display": "American Joint Committee on Cancer pTis(Paget)"
                },
                {
                  "code": "1228957006",
                  "display": "American Joint Committee on Cancer pT1"
                },
                {
                  "code": "1229852009",
                  "display": "American Joint Committee on Cancer pT2"
                },
                {
                  "code": "1229859000",
                  "display": "American Joint Committee on Cancer pT3"
                },
                {
                  "code": "1229864001",
                  "display": "American Joint Committee on Cancer pT4"
                }
              ]
            },
            {
              "system": "http://terminology.hl7.org/CodeSystem/v3-NullFlavor",
              "concept": [
                {
                  "code": "UNK",
                  "display": "unknown"
                }
              ]
            }
          ]
        }
      },
      "request": {
        "method": "PUT",
        "url": "ValueSet/TNMPrimaryTumorVS"
      }
    },
    {
      "resource": {
        "resourceType": "ValueSet",
        "id": "TNMRegionalNodesVS",
        "text": {
          "status": "generated",
          "div": "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p><b>Generated Narrative: ValueSet</b><a name=\"TNMRegionalNodesVS\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource ValueSet &quot;TNMRegionalNodesVS&quot; </p></div><p><b>url</b>: <code>http://hl7.org/fhir/uv/ichom-breast-cancer/ValueSet/TNMRegionalNodesVS</code></p><p><b>version</b>: 5.1</p><p><b>name</b>: TNMRegionalNodesVS</p><p><b>title</b>: TNM Regional Nodes ValueSet</p><p><b>status</b>: active</p><p><b>experimental</b>: false</p><p><b>publisher</b>: ICHOM</p><p><b>description</b>: Valueset of the TNM stage for the N category, according to TNM staging rules</p><p><b>copyright</b>: This value set includes content from SNOMED CT, which is copyright © 2002+ International Health Terminology Standards Development Organisation (IHTSDO), and distributed by agreement between IHTSDO and HL7. Implementer use of SNOMED CT is not covered by this agreement</p><blockquote><p><b>compose</b></p><blockquote><p><b>include</b></p><p><b>system</b>: <a href=\"http://hl7.org/fhir/R4/codesystem-snomedct.html\">SNOMED CT (all versions)</a></p><blockquote><p><b>concept</b></p><p><b>code</b>: 1229966003</p><p><b>display</b>: American Joint Committee on Cancer cNX</p></blockquote><blockquote><p><b>concept</b></p><p><b>code</b>: 1229967007</p><p><b>display</b>: American Joint Committee on Cancer cN0</p></blockquote><blockquote><p><b>concept</b></p><p><b>code</b>: 1229973008</p><p><b>display</b>: American Joint Committee on Cancer cN1</p></blockquote><blockquote><p><b>concept</b></p><p><b>code</b>: 1229978004</p><p><b>display</b>: American Joint Committee on Cancer cN2</p></blockquote><blockquote><p><b>concept</b></p><p><b>code</b>: 1229984001</p><p><b>display</b>: American Joint Committee on Cancer cN3</p></blockquote><blockquote><p><b>concept</b></p><p><b>code</b>: 1229945006</p><p><b>display</b>: American Joint Committee on Cancer pNX</p></blockquote><blockquote><p><b>concept</b></p><p><b>code</b>: 1229947003</p><p><b>display</b>: American Joint Committee on Cancer pN0</p></blockquote><blockquote><p><b>concept</b></p><p><b>code</b>: 1229951001</p><p><b>display</b>: American Joint Committee on Cancer pN1</p></blockquote><blockquote><p><b>concept</b></p><p><b>code</b>: 1229957002</p><p><b>display</b>: American Joint Committee on Cancer pN2</p></blockquote><blockquote><p><b>concept</b></p><p><b>code</b>: 1229962001</p><p><b>display</b>: American Joint Committee on Cancer pN3</p></blockquote></blockquote><blockquote><p><b>include</b></p><p><b>system</b>: <a href=\"http://terminology.hl7.org/5.0.0/CodeSystem-v3-NullFlavor.html\">NullFlavor</a></p><h3>Concepts</h3><table class=\"grid\"><tr><td>-</td><td><b>Code</b></td><td><b>Display</b></td></tr><tr><td>*</td><td>UNK</td><td>unknown</td></tr></table></blockquote></blockquote></div>"
        },
        "url": "http://hl7.org/fhir/uv/ichom-breast-cancer/ValueSet/TNMRegionalNodesVS",
        "version": "5.1",
        "name": "TNMRegionalNodesVS",
        "title": "TNM Regional Nodes ValueSet",
        "status": "active",
        "experimental": false,
        "publisher": "ICHOM",
        "description": "Valueset of the TNM stage for the N category, according to TNM staging rules",
        "copyright": "This value set includes content from SNOMED CT, which is copyright © 2002+ International Health Terminology Standards Development Organisation (IHTSDO), and distributed by agreement between IHTSDO and HL7. Implementer use of SNOMED CT is not covered by this agreement",
        "compose": {
          "include": [
            {
              "system": "http://snomed.info/sct",
              "concept": [
                {
                  "code": "1229966003",
                  "display": "American Joint Committee on Cancer cNX"
                },
                {
                  "code": "1229967007",
                  "display": "American Joint Committee on Cancer cN0"
                },
                {
                  "code": "1229973008",
                  "display": "American Joint Committee on Cancer cN1"
                },
                {
                  "code": "1229978004",
                  "display": "American Joint Committee on Cancer cN2"
                },
                {
                  "code": "1229984001",
                  "display": "American Joint Committee on Cancer cN3"
                },
                {
                  "code": "1229945006",
                  "display": "American Joint Committee on Cancer pNX"
                },
                {
                  "code": "1229947003",
                  "display": "American Joint Committee on Cancer pN0"
                },
                {
                  "code": "1229951001",
                  "display": "American Joint Committee on Cancer pN1"
                },
                {
                  "code": "1229957002",
                  "display": "American Joint Committee on Cancer pN2"
                },
                {
                  "code": "1229962001",
                  "display": "American Joint Committee on Cancer pN3"
                }
              ]
            },
            {
              "system": "http://terminology.hl7.org/CodeSystem/v3-NullFlavor",
              "concept": [
                {
                  "code": "UNK",
                  "display": "unknown"
                }
              ]
            }
          ]
        }
      },
      "request": {
        "method": "PUT",
        "url": "ValueSet/TNMRegionalNodesVS"
      }
    },
    {
      "resource": {
        "resourceType": "ValueSet",
        "id": "TNMDistantMetastasesVS",
        "text": {
          "status": "generated",
          "div": "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p><b>Generated Narrative: ValueSet</b><a name=\"TNMDistantMetastasesVS\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource ValueSet &quot;TNMDistantMetastasesVS&quot; </p></div><p><b>url</b>: <code>http://hl7.org/fhir/uv/ichom-breast-cancer/ValueSet/TNMDistantMetastasesVS</code></p><p><b>version</b>: 5.1</p><p><b>name</b>: TNMDistantMetastasesVS</p><p><b>title</b>: TNM Distant Metastases ValueSet</p><p><b>status</b>: active</p><p><b>experimental</b>: false</p><p><b>publisher</b>: ICHOM</p><p><b>description</b>: Valueset of the TNM stage for the M category, according to TNM staging rules</p><p><b>copyright</b>: This value set includes content from SNOMED CT, which is copyright © 2002+ International Health Terminology Standards Development Organisation (IHTSDO), and distributed by agreement between IHTSDO and HL7. Implementer use of SNOMED CT is not covered by this agreement</p><blockquote><p><b>compose</b></p><blockquote><p><b>include</b></p><p><b>system</b>: <a href=\"http://hl7.org/fhir/R4/codesystem-snomedct.html\">SNOMED CT (all versions)</a></p><blockquote><p><b>concept</b></p><p><b>code</b>: 1229901006</p><p><b>display</b>: American Joint Committee on Cancer cM0</p></blockquote><blockquote><p><b>concept</b></p><p><b>code</b>: 1229903009</p><p><b>display</b>: American Joint Committee on Cancer cM1</p></blockquote><blockquote><p><b>concept</b></p><p><b>code</b>: 1229916009</p><p><b>display</b>: American Joint Committee on Cancer pM1</p></blockquote></blockquote><blockquote><p><b>include</b></p><p><b>system</b>: <a href=\"http://terminology.hl7.org/5.0.0/CodeSystem-v3-NullFlavor.html\">NullFlavor</a></p><h3>Concepts</h3><table class=\"grid\"><tr><td>-</td><td><b>Code</b></td><td><b>Display</b></td></tr><tr><td>*</td><td>UNK</td><td>unknown</td></tr></table></blockquote></blockquote></div>"
        },
        "url": "http://hl7.org/fhir/uv/ichom-breast-cancer/ValueSet/TNMDistantMetastasesVS",
        "version": "5.1",
        "name": "TNMDistantMetastasesVS",
        "title": "TNM Distant Metastases ValueSet",
        "status": "active",
        "experimental": false,
        "publisher": "ICHOM",
        "description": "Valueset of the TNM stage for the M category, according to TNM staging rules",
        "copyright": "This value set includes content from SNOMED CT, which is copyright © 2002+ International Health Terminology Standards Development Organisation (IHTSDO), and distributed by agreement between IHTSDO and HL7. Implementer use of SNOMED CT is not covered by this agreement",
        "compose": {
          "include": [
            {
              "system": "http://snomed.info/sct",
              "concept": [
                {
                  "code": "1229901006",
                  "display": "American Joint Committee on Cancer cM0"
                },
                {
                  "code": "1229903009",
                  "display": "American Joint Committee on Cancer cM1"
                },
                {
                  "code": "1229916009",
                  "display": "American Joint Committee on Cancer pM1"
                }
              ]
            },
            {
              "system": "http://terminology.hl7.org/CodeSystem/v3-NullFlavor",
              "concept": [
                {
                  "code": "UNK",
                  "display": "unknown"
                }
              ]
            }
          ]
        }
      },
      "request": {
        "method": "PUT",
        "url": "ValueSet/TNMDistantMetastasesVS"
      }
    },
    {
      "resource": {
        "resourceType": "ValueSet",
        "id": "EstrogenStatusVS",
        "text": {
          "status": "generated",
          "div": "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p><b>Generated Narrative: ValueSet</b><a name=\"EstrogenStatusVS\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource ValueSet &quot;EstrogenStatusVS&quot; </p></div><p><b>url</b>: <code>http://hl7.org/fhir/uv/ichom-breast-cancer/ValueSet/EstrogenStatusVS</code></p><p><b>version</b>: 5.1</p><p><b>name</b>: EstrogenStatusVS</p><p><b>title</b>: Estrogen receptor status ValueSet</p><p><b>status</b>: active</p><p><b>experimental</b>: false</p><p><b>publisher</b>: ICHOM</p><p><b>description</b>: Valueset of the Estrogen receptor status</p><p><b>copyright</b>: This value set includes content from SNOMED CT, which is copyright © 2002+ International Health Terminology Standards Development Organisation (IHTSDO), and distributed by agreement between IHTSDO and HL7. Implementer use of SNOMED CT is not covered by this agreement</p><blockquote><p><b>compose</b></p><blockquote><p><b>include</b></p><p><b>system</b>: <a href=\"http://hl7.org/fhir/R4/codesystem-snomedct.html\">SNOMED CT (all versions)</a></p><blockquote><p><b>concept</b></p><p><b>code</b>: 373572006</p><p><b>display</b>: Clinical finding absent</p></blockquote><blockquote><p><b>concept</b></p><p><b>code</b>: 416053008</p><p><b>display</b>: Estrogen receptor positive tumor</p></blockquote><blockquote><p><b>concept</b></p><p><b>code</b>: 416237000</p><p><b>display</b>: Procedure not done</p></blockquote></blockquote><blockquote><p><b>include</b></p><p><b>system</b>: <a href=\"http://terminology.hl7.org/5.0.0/CodeSystem-v3-NullFlavor.html\">NullFlavor</a></p><h3>Concepts</h3><table class=\"grid\"><tr><td>-</td><td><b>Code</b></td><td><b>Display</b></td></tr><tr><td>*</td><td>UNK</td><td>unknown</td></tr></table></blockquote></blockquote></div>"
        },
        "url": "http://hl7.org/fhir/uv/ichom-breast-cancer/ValueSet/EstrogenStatusVS",
        "version": "5.1",
        "name": "EstrogenStatusVS",
        "title": "Estrogen receptor status ValueSet",
        "status": "active",
        "experimental": false,
        "publisher": "ICHOM",
        "description": "Valueset of the Estrogen receptor status",
        "copyright": "This value set includes content from SNOMED CT, which is copyright © 2002+ International Health Terminology Standards Development Organisation (IHTSDO), and distributed by agreement between IHTSDO and HL7. Implementer use of SNOMED CT is not covered by this agreement",
        "compose": {
          "include": [
            {
              "system": "http://snomed.info/sct",
              "concept": [
                {
                  "code": "373572006",
                  "display": "Clinical finding absent"
                },
                {
                  "code": "416053008",
                  "display": "Estrogen receptor positive tumor"
                },
                {
                  "code": "416237000",
                  "display": "Procedure not done"
                }
              ]
            },
            {
              "system": "http://terminology.hl7.org/CodeSystem/v3-NullFlavor",
              "concept": [
                {
                  "code": "UNK",
                  "display": "unknown"
                }
              ]
            }
          ]
        }
      },
      "request": {
        "method": "PUT",
        "url": "ValueSet/EstrogenStatusVS"
      }
    },
    {
      "resource": {
        "resourceType": "ValueSet",
        "id": "ProgesteroneStatusVS",
        "text": {
          "status": "generated",
          "div": "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p><b>Generated Narrative: ValueSet</b><a name=\"ProgesteroneStatusVS\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource ValueSet &quot;ProgesteroneStatusVS&quot; </p></div><p><b>url</b>: <code>http://hl7.org/fhir/uv/ichom-breast-cancer/ValueSet/ProgesteroneStatusVS</code></p><p><b>version</b>: 5.1</p><p><b>name</b>: ProgesteroneStatusVS</p><p><b>title</b>: Progesterone receptor status ValueSet</p><p><b>status</b>: active</p><p><b>experimental</b>: false</p><p><b>publisher</b>: ICHOM</p><p><b>description</b>: Valueset of the Progesterone receptor status</p><p><b>copyright</b>: This value set includes content from SNOMED CT, which is copyright © 2002+ International Health Terminology Standards Development Organisation (IHTSDO), and distributed by agreement between IHTSDO and HL7. Implementer use of SNOMED CT is not covered by this agreement</p><blockquote><p><b>compose</b></p><blockquote><p><b>include</b></p><p><b>system</b>: <a href=\"http://hl7.org/fhir/R4/codesystem-snomedct.html\">SNOMED CT (all versions)</a></p><blockquote><p><b>concept</b></p><p><b>code</b>: 441118006</p><p><b>display</b>: Progesterone receptor negative neoplasm</p></blockquote><blockquote><p><b>concept</b></p><p><b>code</b>: 416561008</p><p><b>display</b>: Progesterone receptor positive tumor</p></blockquote><blockquote><p><b>concept</b></p><p><b>code</b>: 416237000</p><p><b>display</b>: Procedure not done</p></blockquote></blockquote><blockquote><p><b>include</b></p><p><b>system</b>: <a href=\"http://terminology.hl7.org/5.0.0/CodeSystem-v3-NullFlavor.html\">NullFlavor</a></p><h3>Concepts</h3><table class=\"grid\"><tr><td>-</td><td><b>Code</b></td><td><b>Display</b></td></tr><tr><td>*</td><td>UNK</td><td>unknown</td></tr></table></blockquote></blockquote></div>"
        },
        "url": "http://hl7.org/fhir/uv/ichom-breast-cancer/ValueSet/ProgesteroneStatusVS",
        "version": "5.1",
        "name": "ProgesteroneStatusVS",
        "title": "Progesterone receptor status ValueSet",
        "status": "active",
        "experimental": false,
        "publisher": "ICHOM",
        "description": "Valueset of the Progesterone receptor status",
        "copyright": "This value set includes content from SNOMED CT, which is copyright © 2002+ International Health Terminology Standards Development Organisation (IHTSDO), and distributed by agreement between IHTSDO and HL7. Implementer use of SNOMED CT is not covered by this agreement",
        "compose": {
          "include": [
            {
              "system": "http://snomed.info/sct",
              "concept": [
                {
                  "code": "441118006",
                  "display": "Progesterone receptor negative neoplasm"
                },
                {
                  "code": "416561008",
                  "display": "Progesterone receptor positive tumor"
                },
                {
                  "code": "416237000",
                  "display": "Procedure not done"
                }
              ]
            },
            {
              "system": "http://terminology.hl7.org/CodeSystem/v3-NullFlavor",
              "concept": [
                {
                  "code": "UNK",
                  "display": "unknown"
                }
              ]
            }
          ]
        }
      },
      "request": {
        "method": "PUT",
        "url": "ValueSet/ProgesteroneStatusVS"
      }
    },
    {
      "resource": {
        "resourceType": "ValueSet",
        "id": "HER2ReceptorStatusVS",
        "text": {
          "status": "generated",
          "div": "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p><b>Generated Narrative: ValueSet</b><a name=\"HER2ReceptorStatusVS\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource ValueSet &quot;HER2ReceptorStatusVS&quot; </p></div><p><b>url</b>: <code>http://hl7.org/fhir/uv/ichom-breast-cancer/ValueSet/HER2ReceptorStatusVS</code></p><p><b>version</b>: 5.1</p><p><b>name</b>: HER2ReceptorStatusVS</p><p><b>title</b>: HER2 receptor status ValueSet</p><p><b>status</b>: active</p><p><b>experimental</b>: false</p><p><b>publisher</b>: ICHOM</p><p><b>description</b>: Valueset of the HER2 receptor status</p><p><b>copyright</b>: This value set includes content from SNOMED CT, which is copyright © 2002+ International Health Terminology Standards Development Organisation (IHTSDO), and distributed by agreement between IHTSDO and HL7. Implementer use of SNOMED CT is not covered by this agreement</p><blockquote><p><b>compose</b></p><blockquote><p><b>include</b></p><p><b>system</b>: <a href=\"http://hl7.org/fhir/R4/codesystem-snomedct.html\">SNOMED CT (all versions)</a></p><blockquote><p><b>concept</b></p><p><b>code</b>: 431396003</p><p><b>display</b>: Human epidermal growth factor 2 negative carcinoma of breast</p></blockquote><blockquote><p><b>concept</b></p><p><b>code</b>: 427685000</p><p><b>display</b>: Human epidermal growth factor 2 positive carcinoma of breast</p></blockquote><blockquote><p><b>concept</b></p><p><b>code</b>: 280414007</p><p><b>display</b>: Equivocal result</p></blockquote><blockquote><p><b>concept</b></p><p><b>code</b>: 416237000</p><p><b>display</b>: Procedure not done</p></blockquote></blockquote></blockquote></div>"
        },
        "url": "http://hl7.org/fhir/uv/ichom-breast-cancer/ValueSet/HER2ReceptorStatusVS",
        "version": "5.1",
        "name": "HER2ReceptorStatusVS",
        "title": "HER2 receptor status ValueSet",
        "status": "active",
        "experimental": false,
        "publisher": "ICHOM",
        "description": "Valueset of the HER2 receptor status",
        "copyright": "This value set includes content from SNOMED CT, which is copyright © 2002+ International Health Terminology Standards Development Organisation (IHTSDO), and distributed by agreement between IHTSDO and HL7. Implementer use of SNOMED CT is not covered by this agreement",
        "compose": {
          "include": [
            {
              "system": "http://snomed.info/sct",
              "concept": [
                {
                  "code": "431396003",
                  "display": "Human epidermal growth factor 2 negative carcinoma of breast"
                },
                {
                  "code": "427685000",
                  "display": "Human epidermal growth factor 2 positive carcinoma of breast"
                },
                {
                  "code": "280414007",
                  "display": "Equivocal result"
                },
                {
                  "code": "416237000",
                  "display": "Procedure not done"
                }
              ]
            }
          ]
        }
      },
      "request": {
        "method": "PUT",
        "url": "ValueSet/HER2ReceptorStatusVS"
      }
    },
    {
      "resource": {
        "resourceType": "CodeSystem",
        "id": "MolecularProfilingCodeSystem",
        "text": {
          "status": "generated",
          "div": "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p><b>Generated Narrative: CodeSystem</b><a name=\"MolecularProfilingCodeSystem\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource CodeSystem &quot;MolecularProfilingCodeSystem&quot; </p></div><p><b>url</b>: <code>http://hl7.org/fhir/uv/ichom-breast-cancer/CodeSystem/MolecularProfilingCodeSystem</code></p><p><b>version</b>: 5.1</p><p><b>name</b>: MolecularProfilingCodeSystem</p><p><b>title</b>: Molecular Profiling CodeSystem</p><p><b>status</b>: active</p><p><b>experimental</b>: false</p><p><b>publisher</b>: ICHOM</p><p><b>description</b>: Codes used to describe the different types of molecular profiling scoring</p><p><b>caseSensitive</b>: true</p><p><b>content</b>: complete</p><p><b>count</b>: 3</p><blockquote><p><b>concept</b></p><p><b>code</b>: mammaprint</p><p><b>display</b>: Mammaprint Score</p></blockquote><blockquote><p><b>concept</b></p><p><b>code</b>: oncotype</p><p><b>display</b>: Oncotype Score</p></blockquote><blockquote><p><b>concept</b></p><p><b>code</b>: endopredict</p><p><b>display</b>: Endopredict Score</p></blockquote></div>"
        },
        "url": "http://hl7.org/fhir/uv/ichom-breast-cancer/CodeSystem/MolecularProfilingCodeSystem",
        "version": "5.1",
        "name": "MolecularProfilingCodeSystem",
        "title": "Molecular Profiling CodeSystem",
        "status": "active",
        "experimental": false,
        "publisher": "ICHOM",
        "description": "Codes used to describe the different types of molecular profiling scoring",
        "caseSensitive": true,
        "content": "complete",
        "count": 3,
        "concept": [
          {
            "code": "mammaprint",
            "display": "Mammaprint Score"
          },
          {
            "code": "oncotype",
            "display": "Oncotype Score"
          },
          {
            "code": "endopredict",
            "display": "Endopredict Score"
          }
        ]
      },
      "request": {
        "method": "PUT",
        "url": "CodeSystem/MolecularProfilingCodeSystem"
      }
    },
    {
      "resource": {
        "resourceType": "ValueSet",
        "id": "MolecularProfilingStatusVS",
        "text": {
          "status": "generated",
          "div": "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p><b>Generated Narrative: ValueSet</b><a name=\"MolecularProfilingStatusVS\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource ValueSet &quot;MolecularProfilingStatusVS&quot; </p></div><p><b>url</b>: <code>http://hl7.org/fhir/uv/ichom-breast-cancer/ValueSet/MolecularProfilingStatusVS</code></p><p><b>version</b>: 5.1</p><p><b>name</b>: MolecularProfilingStatusVS</p><p><b>title</b>: Molecular profiling</p><p><b>status</b>: active</p><p><b>experimental</b>: false</p><p><b>publisher</b>: ICHOM</p><p><b>description</b>: Valueset indicating if a molecular profiling tool was used</p><blockquote><p><b>compose</b></p><blockquote><p><b>include</b></p><p><b>system</b>: <a href=\"Bundle-DebugBundleClinical-01-Baseline.html\">Molecular Profiling CodeSystem</a></p><blockquote><p><b>concept</b></p><p><b>code</b>: mammaprint</p><p><b>display</b>: Mammaprint Score</p></blockquote><blockquote><p><b>concept</b></p><p><b>code</b>: oncotype</p><p><b>display</b>: Oncotype Score</p></blockquote><blockquote><p><b>concept</b></p><p><b>code</b>: endopredict</p><p><b>display</b>: Endopredict Score</p></blockquote></blockquote></blockquote></div>"
        },
        "url": "http://hl7.org/fhir/uv/ichom-breast-cancer/ValueSet/MolecularProfilingStatusVS",
        "version": "5.1",
        "name": "MolecularProfilingStatusVS",
        "title": "Molecular profiling",
        "status": "active",
        "experimental": false,
        "publisher": "ICHOM",
        "description": "Valueset indicating if a molecular profiling tool was used",
        "compose": {
          "include": [
            {
              "system": "http://hl7.org/fhir/uv/ichom-breast-cancer/CodeSystem/MolecularProfilingCodeSystem",
              "concept": [
                {
                  "code": "mammaprint",
                  "display": "Mammaprint Score"
                },
                {
                  "code": "oncotype",
                  "display": "Oncotype Score"
                },
                {
                  "code": "endopredict",
                  "display": "Endopredict Score"
                }
              ]
            }
          ]
        }
      },
      "request": {
        "method": "PUT",
        "url": "ValueSet/MolecularProfilingStatusVS"
      }
    },
    {
      "resource": {
        "resourceType": "ValueSet",
        "id": "RecommendedTreatmentTypeVS",
        "text": {
          "status": "generated",
          "div": "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p><b>Generated Narrative: ValueSet</b><a name=\"RecommendedTreatmentTypeVS\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource ValueSet &quot;RecommendedTreatmentTypeVS&quot; </p></div><p><b>url</b>: <code>http://hl7.org/fhir/uv/ichom-breast-cancer/ValueSet/RecommendedTreatmentTypeVS</code></p><p><b>version</b>: 5.1</p><p><b>name</b>: RecommendedTreatmentTypeVS</p><p><b>title</b>: Recommended treatment types ValueSet</p><p><b>status</b>: active</p><p><b>experimental</b>: false</p><p><b>publisher</b>: ICHOM</p><p><b>description</b>: Valueset of the kind of treatment that the multidisciplinary team recommended</p><p><b>copyright</b>: This value set includes content from SNOMED CT, which is copyright © 2002+ International Health Terminology Standards Development Organisation (IHTSDO), and distributed by agreement between IHTSDO and HL7. Implementer use of SNOMED CT is not covered by this agreement</p><blockquote><p><b>compose</b></p><blockquote><p><b>include</b></p><p><b>system</b>: <a href=\"http://hl7.org/fhir/R4/codesystem-snomedct.html\">SNOMED CT (all versions)</a></p><blockquote><p><b>concept</b></p><p><b>code</b>: 387713003</p><p><b>display</b>: Surgical procedure</p></blockquote><blockquote><p><b>concept</b></p><p><b>code</b>: 108290001</p><p><b>display</b>: Radiation oncology AND/OR radiotherapy</p></blockquote><blockquote><p><b>concept</b></p><p><b>code</b>: 169413002</p><p><b>display</b>: Hormone therapy</p></blockquote><blockquote><p><b>concept</b></p><p><b>code</b>: 76334006</p><p><b>display</b>: Immunotherapy</p></blockquote><blockquote><p><b>concept</b></p><p><b>code</b>: 243114000</p><p><b>display</b>: Support</p></blockquote></blockquote><blockquote><p><b>include</b></p><p><b>system</b>: <a href=\"Bundle-DebugBundleClinical-03-Annual.html\">Treatment variables CodeSytem</a></p><blockquote><p><b>concept</b></p><p><b>code</b>: adjuvant-chemotherapy</p><p><b>display</b>: Adjuvant chemotherapy</p></blockquote><blockquote><p><b>concept</b></p><p><b>code</b>: neoadjuvant-chemotherapy</p><p><b>display</b>: Neoadjuvant chemotherapy</p></blockquote><blockquote><p><b>concept</b></p><p><b>code</b>: targeted-therapy</p><p><b>display</b>: Targeted therapy</p></blockquote></blockquote></blockquote></div>"
        },
        "url": "http://hl7.org/fhir/uv/ichom-breast-cancer/ValueSet/RecommendedTreatmentTypeVS",
        "version": "5.1",
        "name": "RecommendedTreatmentTypeVS",
        "title": "Recommended treatment types ValueSet",
        "status": "active",
        "experimental": false,
        "publisher": "ICHOM",
        "description": "Valueset of the kind of treatment that the multidisciplinary team recommended",
        "copyright": "This value set includes content from SNOMED CT, which is copyright © 2002+ International Health Terminology Standards Development Organisation (IHTSDO), and distributed by agreement between IHTSDO and HL7. Implementer use of SNOMED CT is not covered by this agreement",
        "compose": {
          "include": [
            {
              "system": "http://snomed.info/sct",
              "concept": [
                {
                  "code": "387713003",
                  "display": "Surgical procedure"
                },
                {
                  "code": "108290001",
                  "display": "Radiation oncology AND/OR radiotherapy"
                },
                {
                  "code": "169413002",
                  "display": "Hormone therapy"
                },
                {
                  "code": "76334006",
                  "display": "Immunotherapy"
                },
                {
                  "code": "243114000",
                  "display": "Support"
                }
              ]
            },
            {
              "system": "http://hl7.org/fhir/uv/ichom-breast-cancer/CodeSystem/TreatmentTypesCodeSystem",
              "concept": [
                {
                  "code": "adjuvant-chemotherapy",
                  "display": "Adjuvant chemotherapy"
                },
                {
                  "code": "neoadjuvant-chemotherapy",
                  "display": "Neoadjuvant chemotherapy"
                },
                {
                  "code": "targeted-therapy",
                  "display": "Targeted therapy"
                }
              ]
            }
          ]
        }
      },
      "request": {
        "method": "PUT",
        "url": "ValueSet/RecommendedTreatmentTypeVS"
      }
    },
    {
      "resource": {
        "resourceType": "Questionnaire",
        "id": "ClinicalResponseBaseline",
        "text": {
          "status": "extensions",
          "div": "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p><b>Generated Narrative: Questionnaire</b><a name=\"ClinicalResponseBaseline\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Questionnaire &quot;ClinicalResponseBaseline&quot; </p></div><blockquote><p><b>Launch context resources</b></p><p><b>value</b>: Patient (Details: http://hl7.org/fhir/uv/sdc/CodeSystem/launchContext code patient = 'Patient', stated as 'Patient')</p><p><b>value</b>: Patient</p><p><b>value</b>: Patient information to pre-populate the form with</p></blockquote><p><b>url</b>: <code>http://hl7.org/fhir/uv/ichom-breast-cancer/Questionnaire/ClinicalResponseBaseline</code></p><p><b>name</b>: ClinicalResponseBaseline</p><p><b>title</b>: Clinical response questionnaire at baseline</p><p><b>status</b>: draft</p><p><b>experimental</b>: true</p><p><b>publisher</b>: ICHOM</p><blockquote><p><b>item</b></p><p><b>linkId</b>: General-Information-Clinical</p><p><b>text</b>: General information</p><p><b>type</b>: group</p><p><b>required</b>: true</p><h3>Items</h3><table class=\"grid\"><tr><td>-</td><td><b>Extension</b></td><td><b>LinkId</b></td><td><b>Text</b></td><td><b>Type</b></td><td><b>Required</b></td></tr><tr><td>*</td><td/><td>NA-Clinical</td><td>What is the patient's medical record number?</td><td>string</td><td>true</td></tr><tr><td>*</td><td/><td>LastName-Clinical</td><td>What is the patient's last name?</td><td>string</td><td>true</td></tr></table></blockquote><blockquote><p><b>item</b></p><p><b>linkId</b>: Demographics</p><p><b>text</b>: Demographic factors</p><p><b>type</b>: group</p><p><b>required</b>: true</p><h3>Items</h3><table class=\"grid\"><tr><td>-</td><td><b>Extension</b></td><td><b>LinkId</b></td><td><b>Text</b></td><td><b>Type</b></td><td><b>Required</b></td><td><b>MaxLength</b></td><td><b>AnswerValueSet</b></td></tr><tr><td>*</td><td>, </td><td>Sex</td><td>Indicate the sex of the patient at birth:</td><td>choice</td><td>true</td><td> </td><td><a href=\"http://hl7.org/fhir/R4/valueset-administrative-gender.html\">AdministrativeGender</a></td></tr><tr><td>*</td><td/><td>YearOfBirth</td><td>In what year was the patient born?</td><td>integer</td><td>true</td><td>4</td><td> </td></tr></table></blockquote><blockquote><p><b>item</b></p><p><b>linkId</b>: Clinical-Factors</p><p><b>text</b>: Clinical factors</p><p><b>type</b>: group</p><p><b>required</b>: true</p><blockquote><p><b>item</b></p><p><b>Obervation link period</b>: 300 a<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code a = 'a')</span></p><p><b>Observation extract</b>: true</p><p><b>unitOption</b>: cm (Details: UCUM code cm = 'cm', stated as 'cm')</p><p><b>Min quantity</b>: 10 cm<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code cm = 'cm')</span></p><p><b>Max quantity</b>: 320 cm<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code cm = 'cm')</span></p><p><b>unitOption</b>: [in_i] (Details: UCUM code [in_i] = '[in_i]', stated as '[in_i]')</p><p><b>Min quantity</b>: 3.94 [in_i]<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code [in_i] = '[in_i]')</span></p><p><b>Max quantity</b>: 126 [in_i]<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code [in_i] = '[in_i]')</span></p><p><b>linkId</b>: Height</p><p><b>code</b>: Body height (Details: LOINC code 8302-2 = 'Body height', stated as 'Body height')</p><p><b>text</b>: Indicate the patient's body height</p><p><b>type</b>: quantity</p><p><b>required</b>: true</p></blockquote><blockquote><p><b>item</b></p><p><b>Obervation link period</b>: 300 a<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code a = 'a')</span></p><p><b>Observation extract</b>: true</p><p><b>unitOption</b>: kg (Details: UCUM code kg = 'kg', stated as 'kg')</p><p><b>Min quantity</b>: 0.1 kg<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code kg = 'kg')</span></p><p><b>Max quantity</b>: 750 kg<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code kg = 'kg')</span></p><p><b>unitOption</b>: [lb_av] (Details: UCUM code [lb_av] = '[lb_av]', stated as '[lb_av]')</p><p><b>Min quantity</b>: 0.22 [lb_av]<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code [lb_av] = '[lb_av]')</span></p><p><b>Max quantity</b>: 1653.47 [lb_av]<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code [lb_av] = '[lb_av]')</span></p><p><b>linkId</b>: Weight</p><p><b>code</b>: Body weight (Details: LOINC code 29463-7 = 'Body weight', stated as 'Body weight'), Body weight Measured (Details: LOINC code 3141-9 = 'Body weight Measured', stated as 'Body weight Measured'), Body weight (Details: SNOMED CT code 27113001 = 'Body weight', stated as 'Body weight')</p><p><b>text</b>: Indicate the patient's weight.</p><p><b>type</b>: quantity</p><p><b>required</b>: true</p></blockquote><blockquote><p><b>item</b></p><p><b>linkId</b>: LATERAL</p><p><b>text</b>: Indicate the laterality of breast cancer</p><p><b>type</b>: choice</p><p><b>required</b>: true</p><p><b>answerValueSet</b>: <a href=\"Bundle-DebugBundleClinical-01-Baseline.html\">Laterality of breast cancer ValueSet</a></p></blockquote><blockquote><p><b>item</b></p><p><b>linkId</b>: FIRSTBC</p><p><b>text</b>: Indicate if this is the first breast cancer</p><p><b>type</b>: choice</p><p><b>required</b>: true</p><p><b>answerValueSet</b>: <a href=\"Bundle-DebugBundleClinical-03-Annual.html\">Yes, No and Unknown Valueset</a></p></blockquote><blockquote><p><b>item</b></p><p><b>linkId</b>: NewBC</p><p><b>text</b>: Indicate if this is a new cancer on contralateral or ipsilateral breast</p><p><b>type</b>: choice</p><p><b>required</b>: true</p><p><b>answerValueSet</b>: <a href=\"Bundle-DebugBundleClinical-01-Baseline.html\">Laterality of new cancer ValueSet</a></p></blockquote></blockquote><blockquote><p><b>item</b></p><p><b>linkId</b>: Tumor-Factors</p><p><b>text</b>: Tumor factors</p><p><b>type</b>: group</p><p><b>required</b>: true</p><blockquote><p><b>item</b></p><p><b>linkId</b>: HistologicalDateKnown</p><p><b>text</b>: Is the date of histological diagnosis known?</p><p><b>type</b>: boolean</p><p><b>required</b>: true</p></blockquote><blockquote><p><b>item</b></p><p><b>linkId</b>: HistologicalDiagnosisDate</p><p><b>text</b>: Indicate the initial date of histological diagnosis:</p><p><b>type</b>: date</p><p><b>required</b>: true</p></blockquote><blockquote><p><b>item</b></p><p><b>linkId</b>: HISTOTYPE</p><p><b>text</b>: Indicate the histologic type of the tumor (select all that apply)</p><p><b>type</b>: choice</p><p><b>required</b>: true</p><p><b>repeats</b>: true</p><p><b>answerValueSet</b>: <a href=\"Bundle-DebugBundleClinical-01-Baseline.html\">Histological type of the tumor ValueSet</a></p></blockquote><blockquote><p><b>item</b></p><p><b>linkId</b>: MUTBC</p><p><b>text</b>: Indicate if the patient carries a germline mutation predisposing breast cancer</p><p><b>type</b>: choice</p><p><b>required</b>: true</p><p><b>repeats</b>: true</p><p><b>answerValueSet</b>: <a href=\"Bundle-DebugBundleClinical-03-Annual.html\">Germline Mutation ValueSet</a></p></blockquote><blockquote><p><b>item</b></p><p><b>linkId</b>: GRADEINV</p><p><b>text</b>: Indicate the grade of the invasive component of tumor</p><p><b>type</b>: choice</p><p><b>required</b>: true</p><p><b>answerValueSet</b>: <a href=\"Bundle-DebugBundleClinical-01-Baseline.html\">Grading of tumor ValueSet</a></p></blockquote><blockquote><p><b>item</b></p><p><b>linkId</b>: GRADEDCIS</p><p><b>text</b>: Indicate the tumor grade of DCIS component of tumor</p><p><b>type</b>: choice</p><p><b>required</b>: true</p><p><b>answerValueSet</b>: <a href=\"Bundle-DebugBundleClinical-01-Baseline.html\">Grading of tumor ValueSet</a></p></blockquote><blockquote><p><b>item</b></p><p><b>linkId</b>: TNMCT_BREAST</p><p><b>text</b>: Indicate the clinical tumor stage (per AJCC 8th Ed.):</p><p><b>type</b>: choice</p><p><b>required</b>: true</p><p><b>answerValueSet</b>: <a href=\"Bundle-DebugBundleClinical-02-SixMonths.html\">TNM Primary Tumor ValueSet</a></p></blockquote><blockquote><p><b>item</b></p><p><b>linkId</b>: TNMCN_BREAST</p><p><b>text</b>: Indicate the clinical nodal stage (per AJCC 8th Ed.):</p><p><b>type</b>: choice</p><p><b>required</b>: true</p><p><b>answerValueSet</b>: <a href=\"Bundle-DebugBundleClinical-02-SixMonths.html\">TNM Regional Nodes ValueSet</a></p></blockquote><blockquote><p><b>item</b></p><p><b>linkId</b>: TNMCM_BREAST</p><p><b>text</b>: Indicate the clinical distant metastasis (per AJCC 8th Ed.):</p><p><b>type</b>: choice</p><p><b>required</b>: true</p><p><b>answerValueSet</b>: <a href=\"Bundle-DebugBundleClinical-02-SixMonths.html\">TNM Distant Metastases ValueSet</a></p></blockquote><blockquote><p><b>item</b></p><p><b>linkId</b>: ERSTATUS</p><p><b>text</b>: Indicate if the estrogen receptor status is positive:</p><p><b>type</b>: choice</p><p><b>required</b>: true</p><p><b>answerValueSet</b>: <a href=\"Bundle-DebugBundleClinical-01-Baseline.html\">Estrogen receptor status ValueSet</a></p></blockquote><blockquote><p><b>item</b></p><p><b>linkId</b>: PRSTATUS</p><p><b>text</b>: Indicate if the progesterone receptor status is positive:</p><p><b>type</b>: choice</p><p><b>required</b>: true</p><p><b>answerValueSet</b>: <a href=\"Bundle-DebugBundleClinical-01-Baseline.html\">Progesterone receptor status ValueSet</a></p></blockquote><blockquote><p><b>item</b></p><p><b>linkId</b>: HER2STATUS</p><p><b>text</b>: Indicate if the HER2 receptor status is positive:</p><p><b>type</b>: choice</p><p><b>required</b>: true</p><p><b>answerValueSet</b>: <a href=\"Bundle-DebugBundleClinical-01-Baseline.html\">HER2 receptor status ValueSet</a></p></blockquote><blockquote><p><b>item</b></p><p><b>linkId</b>: MolecularProfiling</p><p><b>text</b>: Indicate if a molecular profiling tool was used. If so, which one?</p><p><b>type</b>: choice</p><p><b>required</b>: true</p><p><b>answerValueSet</b>: <a href=\"Bundle-DebugBundleClinical-01-Baseline.html\">Molecular profiling</a></p></blockquote><blockquote><p><b>item</b></p><p><b>linkId</b>: Mammaprint</p><p><b>text</b>: Indicate the mammaprint score on a scale of 0.000 to 1.000</p><p><b>type</b>: decimal</p><p><b>required</b>: true</p></blockquote><blockquote><p><b>item</b></p><p><b>linkId</b>: Oncotype</p><p><b>text</b>: Indicate the oncotype score on a scale of 0 to 100</p><p><b>type</b>: decimal</p><p><b>required</b>: true</p></blockquote><blockquote><p><b>item</b></p><p><b>linkId</b>: Endopredict</p><p><b>text</b>: Indicate the endopredict score on a scale of 1.1 to 6.2</p><p><b>type</b>: decimal</p><p><b>required</b>: true</p></blockquote></blockquote><blockquote><p><b>item</b></p><p><b>linkId</b>: Treatment-Variables</p><p><b>text</b>: Treatment variables</p><p><b>type</b>: group</p><p><b>required</b>: true</p><blockquote><p><b>item</b></p><p><b>linkId</b>: MultMeet</p><p><b>text</b>: Indicate if a multidisciplinary meeting was conducted</p><p><b>type</b>: choice</p><p><b>required</b>: true</p><p><b>answerValueSet</b>: <a href=\"Bundle-DebugBundleClinical-03-Annual.html\">Yes, No and Unknown Valueset</a></p></blockquote><blockquote><p><b>item</b></p><p><b>linkId</b>: MultRecTreatments</p><p><b>text</b>: Which treatments did the multidisciplinary team recommend (select all that apply)?</p><p><b>type</b>: choice</p><p><b>required</b>: true</p><p><b>repeats</b>: true</p><p><b>answerValueSet</b>: <a href=\"Bundle-DebugBundleClinical-01-Baseline.html\">Recommended treatment types ValueSet</a></p></blockquote></blockquote></div>"
        },
        "extension": [
          {
            "extension": [
              {
                "url": "name",
                "valueCoding": {
                  "system": "http://hl7.org/fhir/uv/sdc/CodeSystem/launchContext",
                  "code": "patient",
                  "display": "Patient"
                }
              },
              {
                "url": "type",
                "valueCode": "Patient"
              },
              {
                "url": "description",
                "valueString": "Patient information to pre-populate the form with"
              }
            ],
            "url": "http://hl7.org/fhir/uv/sdc/StructureDefinition/sdc-questionnaire-launchContext"
          }
        ],
        "url": "http://hl7.org/fhir/uv/ichom-breast-cancer/Questionnaire/ClinicalResponseBaseline",
        "name": "ClinicalResponseBaseline",
        "title": "Clinical response questionnaire at baseline",
        "status": "draft",
        "experimental": true,
        "publisher": "ICHOM",
        "item": [
          {
            "linkId": "General-Information-Clinical",
            "text": "General information",
            "type": "group",
            "required": true,
            "item": [
              {
                "extension": [
                  {
                    "url": "http://hl7.org/fhir/uv/sdc/StructureDefinition/sdc-questionnaire-initialExpression",
                    "valueExpression": {
                      "language": "text/fhirpath",
                      "expression": "%patient.id"
                    }
                  }
                ],
                "linkId": "NA-Clinical",
                "text": "What is the patient's medical record number?",
                "type": "string",
                "required": true
              },
              {
                "extension": [
                  {
                    "url": "http://hl7.org/fhir/uv/sdc/StructureDefinition/sdc-questionnaire-initialExpression",
                    "valueExpression": {
                      "language": "text/fhirpath",
                      "expression": "%patient.name.first().family.first()"
                    }
                  }
                ],
                "linkId": "LastName-Clinical",
                "text": "What is the patient's last name?",
                "type": "string",
                "required": true
              }
            ]
          },
          {
            "linkId": "Demographics",
            "text": "Demographic factors",
            "type": "group",
            "required": true,
            "item": [
              {
                "extension": [
                  {
                    "url": "http://hl7.org/fhir/StructureDefinition/variable",
                    "valueExpression": {
                      "name": "expandedGender",
                      "language": "application/x-fhir-query",
                      "expression": "ValueSet/$expand?url=http://hl7.org/fhir/ValueSet/administrative-gender"
                    }
                  },
                  {
                    "url": "http://hl7.org/fhir/uv/sdc/StructureDefinition/sdc-questionnaire-initialExpression",
                    "valueExpression": {
                      "language": "text/fhirpath",
                      "expression": "%expandedGender.expansion.contains.where(code=%patient.gender)"
                    }
                  }
                ],
                "linkId": "Sex",
                "text": "Indicate the sex of the patient at birth:",
                "type": "choice",
                "required": true,
                "answerValueSet": "http://hl7.org/fhir/ValueSet/administrative-gender"
              },
              {
                "extension": [
                  {
                    "url": "http://hl7.org/fhir/uv/sdc/StructureDefinition/sdc-questionnaire-initialExpression",
                    "valueExpression": {
                      "language": "text/fhirpath",
                      "expression": "%patient.birthDate.substring(0,4)"
                    }
                  }
                ],
                "linkId": "YearOfBirth",
                "text": "In what year was the patient born?",
                "type": "integer",
                "required": true,
                "maxLength": 4
              }
            ]
          },
          {
            "linkId": "Clinical-Factors",
            "text": "Clinical factors",
            "type": "group",
            "required": true,
            "item": [
              {
                "extension": [
                  {
                    "url": "http://hl7.org/fhir/uv/sdc/StructureDefinition/sdc-questionnaire-observationLinkPeriod",
                    "valueDuration": {
                      "value": 300,
                      "system": "http://unitsofmeasure.org",
                      "code": "a"
                    }
                  },
                  {
                    "url": "http://hl7.org/fhir/uv/sdc/StructureDefinition/sdc-questionnaire-observationExtract",
                    "valueBoolean": true
                  },
                  {
                    "url": "http://hl7.org/fhir/StructureDefinition/questionnaire-unitOption",
                    "valueCoding": {
                      "system": "http://unitsofmeasure.org",
                      "code": "cm",
                      "display": "cm"
                    }
                  },
                  {
                    "url": "http://hl7.org/fhir/uv/sdc/StructureDefinition/sdc-questionnaire-minQuantity",
                    "valueQuantity": {
                      "value": 10,
                      "system": "http://unitsofmeasure.org",
                      "code": "cm"
                    }
                  },
                  {
                    "url": "http://hl7.org/fhir/uv/sdc/StructureDefinition/sdc-questionnaire-maxQuantity",
                    "valueQuantity": {
                      "value": 320,
                      "system": "http://unitsofmeasure.org",
                      "code": "cm"
                    }
                  },
                  {
                    "url": "http://hl7.org/fhir/StructureDefinition/questionnaire-unitOption",
                    "valueCoding": {
                      "system": "http://unitsofmeasure.org",
                      "code": "[in_i]",
                      "display": "[in_i]"
                    }
                  },
                  {
                    "url": "http://hl7.org/fhir/uv/sdc/StructureDefinition/sdc-questionnaire-minQuantity",
                    "valueQuantity": {
                      "value": 3.94,
                      "system": "http://unitsofmeasure.org",
                      "code": "[in_i]"
                    }
                  },
                  {
                    "url": "http://hl7.org/fhir/uv/sdc/StructureDefinition/sdc-questionnaire-maxQuantity",
                    "valueQuantity": {
                      "value": 126,
                      "system": "http://unitsofmeasure.org",
                      "code": "[in_i]"
                    }
                  }
                ],
                "linkId": "Height",
                "code": [
                  {
                    "system": "http://loinc.org",
                    "code": "8302-2",
                    "display": "Body height"
                  }
                ],
                "text": "Indicate the patient's body height",
                "type": "quantity",
                "required": true
              },
              {
                "extension": [
                  {
                    "url": "http://hl7.org/fhir/uv/sdc/StructureDefinition/sdc-questionnaire-observationLinkPeriod",
                    "valueDuration": {
                      "value": 300,
                      "system": "http://unitsofmeasure.org",
                      "code": "a"
                    }
                  },
                  {
                    "url": "http://hl7.org/fhir/uv/sdc/StructureDefinition/sdc-questionnaire-observationExtract",
                    "valueBoolean": true
                  },
                  {
                    "url": "http://hl7.org/fhir/StructureDefinition/questionnaire-unitOption",
                    "valueCoding": {
                      "system": "http://unitsofmeasure.org",
                      "code": "kg",
                      "display": "kg"
                    }
                  },
                  {
                    "url": "http://hl7.org/fhir/uv/sdc/StructureDefinition/sdc-questionnaire-minQuantity",
                    "valueQuantity": {
                      "value": 0.1,
                      "system": "http://unitsofmeasure.org",
                      "code": "kg"
                    }
                  },
                  {
                    "url": "http://hl7.org/fhir/uv/sdc/StructureDefinition/sdc-questionnaire-maxQuantity",
                    "valueQuantity": {
                      "value": 750,
                      "system": "http://unitsofmeasure.org",
                      "code": "kg"
                    }
                  },
                  {
                    "url": "http://hl7.org/fhir/StructureDefinition/questionnaire-unitOption",
                    "valueCoding": {
                      "system": "http://unitsofmeasure.org",
                      "code": "[lb_av]",
                      "display": "[lb_av]"
                    }
                  },
                  {
                    "url": "http://hl7.org/fhir/uv/sdc/StructureDefinition/sdc-questionnaire-minQuantity",
                    "valueQuantity": {
                      "value": 0.22,
                      "system": "http://unitsofmeasure.org",
                      "code": "[lb_av]"
                    }
                  },
                  {
                    "url": "http://hl7.org/fhir/uv/sdc/StructureDefinition/sdc-questionnaire-maxQuantity",
                    "valueQuantity": {
                      "value": 1653.47,
                      "system": "http://unitsofmeasure.org",
                      "code": "[lb_av]"
                    }
                  }
                ],
                "linkId": "Weight",
                "code": [
                  {
                    "system": "http://loinc.org",
                    "code": "29463-7",
                    "display": "Body weight"
                  },
                  {
                    "system": "http://loinc.org",
                    "code": "3141-9",
                    "display": "Body weight Measured"
                  },
                  {
                    "system": "http://snomed.info/sct",
                    "code": "27113001",
                    "display": "Body weight"
                  }
                ],
                "text": "Indicate the patient's weight.",
                "type": "quantity",
                "required": true
              },
              {
                "linkId": "LATERAL",
                "text": "Indicate the laterality of breast cancer",
                "type": "choice",
                "required": true,
                "answerValueSet": "http://hl7.org/fhir/uv/ichom-breast-cancer/ValueSet/LateralityVS"
              },
              {
                "linkId": "FIRSTBC",
                "text": "Indicate if this is the first breast cancer",
                "type": "choice",
                "required": true,
                "answerValueSet": "http://hl7.org/fhir/uv/ichom-breast-cancer/ValueSet/NoYesUnknownVS"
              },
              {
                "linkId": "NewBC",
                "text": "Indicate if this is a new cancer on contralateral or ipsilateral breast",
                "type": "choice",
                "enableWhen": [
                  {
                    "question": "FIRSTBC",
                    "operator": "=",
                    "answerCoding": {
                      "system": "http://terminology.hl7.org/CodeSystem/v2-0532",
                      "code": "N"
                    }
                  }
                ],
                "required": true,
                "answerValueSet": "http://hl7.org/fhir/uv/ichom-breast-cancer/ValueSet/LateralityNewCancerVS"
              }
            ]
          },
          {
            "linkId": "Tumor-Factors",
            "text": "Tumor factors",
            "type": "group",
            "required": true,
            "item": [
              {
                "linkId": "HistologicalDateKnown",
                "text": "Is the date of histological diagnosis known?",
                "type": "boolean",
                "required": true
              },
              {
                "linkId": "HistologicalDiagnosisDate",
                "text": "Indicate the initial date of histological diagnosis:",
                "type": "date",
                "enableWhen": [
                  {
                    "question": "HistologicalDateKnown",
                    "operator": "=",
                    "answerBoolean": true
                  }
                ],
                "required": true
              },
              {
                "linkId": "HISTOTYPE",
                "text": "Indicate the histologic type of the tumor (select all that apply)",
                "type": "choice",
                "required": true,
                "repeats": true,
                "answerValueSet": "http://hl7.org/fhir/uv/ichom-breast-cancer/ValueSet/HistologicalTypeVS"
              },
              {
                "linkId": "MUTBC",
                "text": "Indicate if the patient carries a germline mutation predisposing breast cancer",
                "type": "choice",
                "required": true,
                "repeats": true,
                "answerValueSet": "http://hl7.org/fhir/uv/ichom-breast-cancer/ValueSet/GermlineMutationVS"
              },
              {
                "linkId": "GRADEINV",
                "text": "Indicate the grade of the invasive component of tumor",
                "type": "choice",
                "required": true,
                "answerValueSet": "http://hl7.org/fhir/uv/ichom-breast-cancer/ValueSet/GradingVS"
              },
              {
                "linkId": "GRADEDCIS",
                "text": "Indicate the tumor grade of DCIS component of tumor",
                "type": "choice",
                "required": true,
                "answerValueSet": "http://hl7.org/fhir/uv/ichom-breast-cancer/ValueSet/GradingVS"
              },
              {
                "linkId": "TNMCT_BREAST",
                "text": "Indicate the clinical tumor stage (per AJCC 8th Ed.):",
                "type": "choice",
                "required": true,
                "answerValueSet": "http://hl7.org/fhir/uv/ichom-breast-cancer/ValueSet/TNMPrimaryTumorVS"
              },
              {
                "linkId": "TNMCN_BREAST",
                "text": "Indicate the clinical nodal stage (per AJCC 8th Ed.):",
                "type": "choice",
                "required": true,
                "answerValueSet": "http://hl7.org/fhir/uv/ichom-breast-cancer/ValueSet/TNMRegionalNodesVS"
              },
              {
                "linkId": "TNMCM_BREAST",
                "text": "Indicate the clinical distant metastasis (per AJCC 8th Ed.):",
                "type": "choice",
                "required": true,
                "answerValueSet": "http://hl7.org/fhir/uv/ichom-breast-cancer/ValueSet/TNMDistantMetastasesVS"
              },
              {
                "linkId": "ERSTATUS",
                "text": "Indicate if the estrogen receptor status is positive:",
                "type": "choice",
                "required": true,
                "answerValueSet": "http://hl7.org/fhir/uv/ichom-breast-cancer/ValueSet/EstrogenStatusVS"
              },
              {
                "linkId": "PRSTATUS",
                "text": "Indicate if the progesterone receptor status is positive:",
                "type": "choice",
                "required": true,
                "answerValueSet": "http://hl7.org/fhir/uv/ichom-breast-cancer/ValueSet/ProgesteroneStatusVS"
              },
              {
                "linkId": "HER2STATUS",
                "text": "Indicate if the HER2 receptor status is positive:",
                "type": "choice",
                "required": true,
                "answerValueSet": "http://hl7.org/fhir/uv/ichom-breast-cancer/ValueSet/HER2ReceptorStatusVS"
              },
              {
                "linkId": "MolecularProfiling",
                "text": "Indicate if a molecular profiling tool was used. If so, which one?",
                "type": "choice",
                "required": true,
                "answerValueSet": "http://hl7.org/fhir/uv/ichom-breast-cancer/ValueSet/MolecularProfilingStatusVS"
              },
              {
                "linkId": "Mammaprint",
                "text": "Indicate the mammaprint score on a scale of 0.000 to 1.000",
                "type": "decimal",
                "enableWhen": [
                  {
                    "question": "MolecularProfiling",
                    "operator": "=",
                    "answerCoding": {
                      "system": "http://hl7.org/fhir/uv/ichom-breast-cancer/CodeSystem/MolecularProfilingCodeSystem",
                      "code": "mammaprint"
                    }
                  }
                ],
                "required": true
              },
              {
                "linkId": "Oncotype",
                "text": "Indicate the oncotype score on a scale of 0 to 100",
                "type": "decimal",
                "enableWhen": [
                  {
                    "question": "MolecularProfiling",
                    "operator": "=",
                    "answerCoding": {
                      "system": "http://hl7.org/fhir/uv/ichom-breast-cancer/CodeSystem/MolecularProfilingCodeSystem",
                      "code": "oncotype"
                    }
                  }
                ],
                "required": true
              },
              {
                "linkId": "Endopredict",
                "text": "Indicate the endopredict score on a scale of 1.1 to 6.2",
                "type": "decimal",
                "enableWhen": [
                  {
                    "question": "MolecularProfiling",
                    "operator": "=",
                    "answerCoding": {
                      "system": "http://hl7.org/fhir/uv/ichom-breast-cancer/CodeSystem/MolecularProfilingCodeSystem",
                      "code": "endopredict"
                    }
                  }
                ],
                "required": true
              }
            ]
          },
          {
            "linkId": "Treatment-Variables",
            "text": "Treatment variables",
            "type": "group",
            "required": true,
            "item": [
              {
                "linkId": "MultMeet",
                "text": "Indicate if a multidisciplinary meeting was conducted",
                "type": "choice",
                "required": true,
                "answerValueSet": "http://hl7.org/fhir/uv/ichom-breast-cancer/ValueSet/NoYesUnknownVS"
              },
              {
                "linkId": "MultRecTreatments",
                "text": "Which treatments did the multidisciplinary team recommend (select all that apply)?",
                "type": "choice",
                "enableWhen": [
                  {
                    "question": "MultMeet",
                    "operator": "=",
                    "answerCoding": {
                      "system": "http://terminology.hl7.org/CodeSystem/v2-0532",
                      "code": "Y"
                    }
                  }
                ],
                "required": true,
                "repeats": true,
                "answerValueSet": "http://hl7.org/fhir/uv/ichom-breast-cancer/ValueSet/RecommendedTreatmentTypeVS"
              }
            ]
          }
        ]
      },
      "request": {
        "method": "PUT",
        "url": "Questionnaire/ClinicalResponseBaseline"
      }
    }
  ]
}