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Packagehl7.fhir.uv.genomics-reporting.r4
Resource TypeTask
IdTask-PGxRecEx03.json
FHIR VersionR4

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Narrative

Note: links and images are rebased to the (stated) source

Generated Narrative: Task PGxRecEx03

status: Requested

intent: proposal

code: Decrease dose

description: For citalopram, a 50% reduction in starting dose is recommended with therapeutic drug monitoring to guide dose adjustment or select an alternate drug not predominantly metabolized by CYP2C19. Refer to current guidelines for dosage and recommendations at https://cpicpgx.org/guidelines/guideline-for-selective-serotonin-reuptake-inhibitors-and-cyp2d6-and-cyp2c19/. If CYP2D6 genotyping is available, refer to the current guidelines for dosing recommendations.

for: Adam B. Everyman Male, DoB: 1951-01-20 ( Medical Record Number: m123 (use: usual, ))

reasonReference: Poor metabolizer

Source1

{
  "resourceType": "Task",
  "id": "PGxRecEx03",
  "meta": {
    "profile": [
      "http://hl7.org/fhir/uv/genomics-reporting/StructureDefinition/followup-recommendation"
    ]
  },
  "text": {
    "status": "generated",
    "div": "<!-- snip (see above) -->"
  },
  "status": "requested",
  "intent": "proposal",
  "code": {
    "coding": [
      {
        "system": "http://loinc.org",
        "code": "LA26422-8",
        "display": "Decrease dose"
      }
    ]
  },
  "description": "For citalopram, a 50% reduction in starting dose is recommended with therapeutic drug monitoring to guide dose adjustment or select an alternate drug not predominantly metabolized by CYP2C19. Refer to current guidelines for dosage and recommendations at https://cpicpgx.org/guidelines/guideline-for-selective-serotonin-reuptake-inhibitors-and-cyp2d6-and-cyp2c19/. If CYP2D6 genotyping is available, refer to the current guidelines for dosing recommendations.",
  "for": {
    "reference": "Patient/CGPatientExample01"
  },
  "reasonReference": {
    "reference": "Observation/TxImp03",
    "display": "Poor metabolizer"
  }
}