Package | hl7.fhir.uv.genomics-reporting |
Type | CodeSystem |
Id | pharmgkb-evidence-level-custom-cs |
FHIR Version | R4 |
Source | http://hl7.org/fhir/uv/genomics-reporting/https://build.fhir.org/ig/HL7/genomics-reporting/CodeSystem-pharmgkb-evidence-level-custom-cs.html |
URL | http://hl7.org/fhir/uv/genomics-reporting/CodeSystem/pharmgkb-evidence-level-custom-cs |
Version | 4.0.0-ballot |
Status | active |
Date | 2025-06-24T17:31:37+00:00 |
Name | PharmGKBEvidenceLevelCustomCS |
Title | PharmGKB Evidence Level Example Codes |
Realm | uv |
Authority | hl7 |
Description | PharmGKB contains examples of evidence level concepts that are not conflated with clinical significance. These can be found on PharmGKB https://www.pharmgkb.org/page/clinAnnLevels. These examples are informational only, for copyright information contact the relevant source. |
Content | complete |
ValueSet | |
evidence-level-example-vs | Evidence Level Examples |
No resources found
Note: links and images are rebased to the (stated) source
Generated Narrative: CodeSystem pharmgkb-evidence-level-custom-cs
This case-sensitive code system http://hl7.org/fhir/uv/genomics-reporting/CodeSystem/pharmgkb-evidence-level-custom-cs
defines the following codes:
{ "resourceType": "CodeSystem", "id": "pharmgkb-evidence-level-custom-cs", "text": { "status": "generated", "div": "<!-- snip (see above) -->" }, "extension": [ { "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-wg", "valueCode": "cg" }, { "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status", "valueCode": "informative", "_valueCode": { "extension": [ { "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-conformance-derivedFrom", "valueCanonical": "http://hl7.org/fhir/uv/genomics-reporting/ImplementationGuide/genomics-reporting" } ] } } ], "url": "http://hl7.org/fhir/uv/genomics-reporting/CodeSystem/pharmgkb-evidence-level-custom-cs", "version": "4.0.0-ballot", "name": "PharmGKBEvidenceLevelCustomCS", "title": "PharmGKB Evidence Level Example Codes", "status": "active", "experimental": true, "date": "2025-06-24T17:31:37+00:00", "publisher": "HL7 International / Clinical Genomics", "contact": [ { "name": "HL7 International / Clinical Genomics", "telecom": [ { "system": "url", "value": "http://www.hl7.org/Special/committees/clingenomics" }, { "system": "email", "value": "cg@lists.HL7.org" } ] } ], "description": "PharmGKB contains examples of evidence level concepts that are not conflated with clinical significance. These can be found on PharmGKB https://www.pharmgkb.org/page/clinAnnLevels. These examples are informational only, for copyright information contact the relevant source.", "jurisdiction": [ { "coding": [ { "system": "http://unstats.un.org/unsd/methods/m49/m49.htm", "code": "001", "display": "World" } ] } ], "caseSensitive": true, "content": "complete", "count": 6, "concept": [ { "code": "1A", "display": "PGKB 1A", "definition": "High level of evidence. Supported by a guideline or FDA label with variant specific prescribing guidance. Additionally, supported by at least one publication." }, { "code": "1B", "display": "PGKB 1B", "definition": "High level of evidence. But, NOT supported by a guideline or FDA label with variant specific prescribing guidance. Additionally, supported by at least one publication." }, { "code": "2A", "display": "PGKB 2A", "definition": "Moderate level of evidence. Supported by being a KNOWN pharmacogene on https://www.pharmgkb.org/vips. Also, found in multiple studies but may have a minority of studies that did not support the majority opinion. Supported by at least two indpendent publications." }, { "code": "2B", "display": "PGKB 2B", "definition": "Moderate level of evidence. NOT in the list of very important, KNOWN pharmacogenes. Found in multiple studies but may have a minority of studies that did not support the majority opinion. Supported by at least two indpendent publications." }, { "code": "3", "display": "PGKB 3", "definition": "Low-level of evidence. Where either the assocation is based on a single study, failed to be reproduced, or preliminary evidence." }, { "code": "4", "display": "PGKB 4", "definition": "The evidence does not support an association between the variant and the drug phenotype. (negative)" } ] }