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Narrative

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Source1

{
  "resourceType": "ClinicalUseDefinition",
  "id": "cud-diflucan-renal",
  "meta": {
    "profile": [
      "http://hl7.org/fhir/uv/emedicinal-product-info/StructureDefinition/ClinicalUseDefinition-warning-uv-epi"
    ]
  },
  "text": {
    "status": "generated",
    "div": "<!-- snip (see above) -->"
  },
  "identifier": [
    {
      "system": "http://example.org/identifier",
      "value": "cud-diflucan-renal"
    }
  ],
  "type": "warning",
  "category": [
    {
      "coding": [
        {
          "system": "http://hl7.org/fhir/uv/emedicinal-product-info/CodeSystem/epi-ig",
          "code": "warning",
          "display": "Warning"
        }
      ]
    }
  ],
  "subject": [
    {
      "reference": "http://hl7.org/fhir/uv/emedicinal-product-info/MedicinalProductDefinition/mpd-diflucan"
    }
  ],
  "status": {
    "coding": [
      {
        "system": "http://hl7.org/fhir/publication-status",
        "code": "active",
        "display": "Active"
      }
    ]
  },
  "population": [
    {
      "reference": "Group/group-diflucan-renal",
      "display": "Renal impairment (CrCl ≤ 50 mL/min)"
    }
  ],
  "warning": {
    "code": {
      "coding": [
        {
          "system": "http://snomed.info/sct",
          "code": "723188008",
          "display": "Renal insufficiency"
        }
      ],
      "text": "For multiple-dose therapy, after a normal loading dose, give 50% of the recommended daily dose when CrCl ≤ 50 mL/min (no haemodialysis); give 100% of the recommended dose after each haemodialysis session. Single-dose therapy needs no adjustment. This rule applies to every multiple-dose indication."
    }
  }
}