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Source1

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  "title": "A Study of Nasal Glucagon (LY900018) in Japanese Participants With Diabetes Mellitus",
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        {
          "name": "Percentage of Participants Achieving Treatment Success During Controlled Insulin-Induced Hypoglycemia",
          "type": {
            "coding": [
              {
                "system": "http://terminology.hl7.org/CodeSystem/research-study-objective-type",
                "code": "primary",
                "display": "Primary"
              }
            ]
          },
          "description": "Percentage of participants who achieved treatment success during the controlled insulin-induced hypoglycemia in participants with type 1 diabetes mellitus (T1DM) and participants with type 2 diabetes mellitus (T2DM).Treatment success is defined as an increase in plasma glucose to greater than or equal to (≥) 70 milligrams per deciliter (mg/dL) or an increase of ≥20 mg/dL from plasma glucose nadir, without receiving additional actions to increase the plasma glucose concentration. Nadir is defined as the minimum plasma glucose concentration at the time of or within 10 minutes following glucagon administration.",
          "endpoint": {
            "reference": "EvidenceVariable/267226",
            "type": "EvidenceVariable",
            "identifier": {
              "type": {
                "text": "FEvIR Linking Identifier"
              },
              "system": "https://fevir.net/FLI",
              "value": "NCT03421379-primaryOutcome-0",
              "assigner": {
                "display": "Computable Publishing LLC"
              }
            },
            "display": "Percentage of Participants Achieving Treatment Success During Controlled Insulin-Induced Hypoglycemia"
          }
        }
      ]
    },
    {
      "type": {
        "coding": [
          {
            "system": "http://terminology.hl7.org/CodeSystem/research-study-objective-type",
            "code": "secondary",
            "display": "Secondary"
          }
        ]
      },
      "outcomeMeasure": [
        {
          "name": "Pharmacodynamics (PD): Change From Baseline in Maximal Blood Glucose (BGmax) of Glucagon Nasal Powder and Glucagon Hydrochloride Intramuscular (IM)",
          "type": {
            "coding": [
              {
                "system": "http://terminology.hl7.org/CodeSystem/research-study-objective-type",
                "code": "secondary",
                "display": "Secondary"
              }
            ]
          },
          "description": "PD assessment measured the change from Baseline in maximal blood glucose (BGmax) of Glucagon Nasal Powder and Glucagon Hydrochloride intramuscular (IM).",
          "endpoint": {
            "reference": "EvidenceVariable/267227",
            "type": "EvidenceVariable",
            "identifier": {
              "type": {
                "text": "FEvIR Linking Identifier"
              },
              "system": "https://fevir.net/FLI",
              "value": "NCT03421379-secondaryOutcome-0",
              "assigner": {
                "display": "Computable Publishing LLC"
              }
            },
            "display": "Pharmacodynamics (PD): Change From Baseline in Maximal Blood Glucose (BGmax) of Glucagon Nasal Powder and Glucagon Hydrochloride Intramuscular (IM)"
          }
        },
        {
          "name": "PD: Time to Maximal Concentration (Tmax) of Glucagon Nasal Powder and Glucagon Hydrochloride IM",
          "type": {
            "coding": [
              {
                "system": "http://terminology.hl7.org/CodeSystem/research-study-objective-type",
                "code": "secondary",
                "display": "Secondary"
              }
            ]
          },
          "description": "PD assessment measured the time to maximal concentration (Tmax) of Glucagon Nasal Powder and Glucagon Hydrochloride IM.",
          "endpoint": {
            "reference": "EvidenceVariable/267228",
            "type": "EvidenceVariable",
            "identifier": {
              "type": {
                "text": "FEvIR Linking Identifier"
              },
              "system": "https://fevir.net/FLI",
              "value": "NCT03421379-secondaryOutcome-1",
              "assigner": {
                "display": "Computable Publishing LLC"
              }
            },
            "display": "PD: Time to Maximal Concentration (Tmax) of Glucagon Nasal Powder and Glucagon Hydrochloride IM"
          }
        },
        {
          "name": "Pharmacokinetics (PK): Change From Baseline in Area Under the Concentration Versus Time Curve From Zero to Time t (AUC [0-tLast]) of Glucagon Nasal Powder and Glucagon Hydrochloride IM",
          "type": {
            "coding": [
              {
                "system": "http://terminology.hl7.org/CodeSystem/research-study-objective-type",
                "code": "secondary",
                "display": "Secondary"
              }
            ]
          },
          "description": "PK assessment measured the change from baseline in the area under the concentration versus time curve from time zero to time t, where t is the last time point with a measurable concentration of Glucagon Nasal Powder and Glucagon Hydrochloride IM.",
          "endpoint": {
            "reference": "EvidenceVariable/267229",
            "type": "EvidenceVariable",
            "identifier": {
              "type": {
                "text": "FEvIR Linking Identifier"
              },
              "system": "https://fevir.net/FLI",
              "value": "NCT03421379-secondaryOutcome-2",
              "assigner": {
                "display": "Computable Publishing LLC"
              }
            },
            "display": "Pharmacokinetics (PK): Change From Baseline in Area Under the Concentration Versus Time Curve From Zero to Time t (AUC [0-tLast]) of Glucagon Nasal Powder and Glucagon Hydrochloride IM"
          }
        },
        {
          "name": "PK: Change From Baseline in Maximal Concentration (Cmax) of Glucagon Nasal Powder and Glucagon Hydrochloride IM",
          "type": {
            "coding": [
              {
                "system": "http://terminology.hl7.org/CodeSystem/research-study-objective-type",
                "code": "secondary",
                "display": "Secondary"
              }
            ]
          },
          "description": "PK assessment measured the change from baseline in maximal concentration (Cmax) of glucagon nasal powder and glucagon hydrochloride IM.",
          "endpoint": {
            "reference": "EvidenceVariable/267230",
            "type": "EvidenceVariable",
            "identifier": {
              "type": {
                "text": "FEvIR Linking Identifier"
              },
              "system": "https://fevir.net/FLI",
              "value": "NCT03421379-secondaryOutcome-3",
              "assigner": {
                "display": "Computable Publishing LLC"
              }
            },
            "display": "PK: Change From Baseline in Maximal Concentration (Cmax) of Glucagon Nasal Powder and Glucagon Hydrochloride IM"
          }
        },
        {
          "name": "PK: Change From Baseline in Tmax of Glucagon Nasal Powder and Glucagon Hydrochloride IM",
          "type": {
            "coding": [
              {
                "system": "http://terminology.hl7.org/CodeSystem/research-study-objective-type",
                "code": "secondary",
                "display": "Secondary"
              }
            ]
          },
          "description": "PK assessment measured the change from baseline in Tmax of Glucagon Nasal Powder and Glucagon Hydrochloride IM.",
          "endpoint": {
            "reference": "EvidenceVariable/267231",
            "type": "EvidenceVariable",
            "identifier": {
              "type": {
                "text": "FEvIR Linking Identifier"
              },
              "system": "https://fevir.net/FLI",
              "value": "NCT03421379-secondaryOutcome-4",
              "assigner": {
                "display": "Computable Publishing LLC"
              }
            },
            "display": "PK: Change From Baseline in Tmax of Glucagon Nasal Powder and Glucagon Hydrochloride IM"
          }
        }
      ]
    }
  ],
  "result": [
    {
      "reference": "Composition/267224",
      "type": "Composition",
      "identifier": {
        "type": {
          "text": "FEvIR Linking Identifier"
        },
        "system": "https://fevir.net/FLI",
        "value": "NCT03421379 Results Report",
        "assigner": {
          "display": "Computable Publishing LLC"
        }
      },
      "display": "Results Section for NCT03421379"
    }
  ]
}