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Source1

{
  "resourceType": "Group",
  "id": "279347",
  "meta": {
    "versionId": "15",
    "lastUpdated": "2025-03-15T21:00:37.685Z",
    "profile": [
      "http://hl7.org/fhir/uv/ebm/StructureDefinition/conceptual-cohort-definition"
    ]
  },
  "language": "en",
  "text": {
    "status": "empty",
    "div": "<!-- snip (see above) -->"
  },
  "extension": [
    {
      "url": "http://hl7.org/fhir/StructureDefinition/artifact-author",
      "valueContactDetail": {
        "name": "Brian S. Alper"
      }
    },
    {
      "url": "http://hl7.org/fhir/uv/ebm/StructureDefinition/cite-as",
      "valueMarkdown": "ConceptualCohortDefinition: T1DM-specific criteria [Database Entry: FHIR Group Resource]. Contributors: Brian S. Alper [Authors/Creators]. In: Fast Evidence Interoperability Resources (FEvIR) Platform, FOI 279347. Revised 2024-11-16. Available at: https://fevir.net/resources/Group/279347. Computable resource at: https://fevir.net/resources/Group/279347#json."
    },
    {
      "url": "http://hl7.org/fhir/uv/ebm/StructureDefinition/artifact-publication-status",
      "valueCodeableConcept": {
        "coding": [
          {
            "system": "http://terminology.hl7.org/CodeSystem/cited-artifact-status-type",
            "code": "active",
            "display": "Active"
          }
        ]
      }
    }
  ],
  "url": "https://fevir.net/resources/Group/279347",
  "identifier": [
    {
      "type": {
        "coding": [
          {
            "system": "http://terminology.hl7.org/CodeSystem/v2-0203",
            "code": "ACSN",
            "display": "Accession ID"
          }
        ],
        "text": "FEvIR Object Identifier"
      },
      "system": "https://fevir.net/FOI",
      "value": "279347",
      "assigner": {
        "display": "Computable Publishing LLC"
      }
    }
  ],
  "title": "ConceptualCohortDefinition: T1DM-specific criteria",
  "status": "active",
  "publisher": "Computable Publishing LLC",
  "contact": [
    {
      "telecom": [
        {
          "system": "email",
          "value": "support@computablepublishing.com"
        }
      ]
    }
  ],
  "description": "i. Diagnosis of T1DM based on the World Health Organization (WHO) diagnostic criteria\nii. have been on the following daily insulin therapy for at least 1 year\n..1) multiple daily injection of long-acting insulin analog (either insulin glargine [U-100 or U-300] or insulin degludec [U-100]) and rapid-acting insulin analog (insulin lispro, insulin aspart, or insulin glulisine), or...2) continuous subcutaneous insulin infusion (CSII)\niii. are between 18 and 64 years old at the time of informed consent\niv. have a body mass index of 18.5 to 30.0 kg/m2 at the time of screening",
  "copyright": "https://creativecommons.org/licenses/by-nc-sa/4.0/",
  "membership": "conceptual",
  "combinationMethod": "all-of",
  "characteristic": [
    {
      "code": {
        "coding": [
          {
            "system": "http://snomed.info/sct",
            "code": "64572001",
            "display": "Disease (disorder)"
          }
        ]
      },
      "valueCodeableConcept": {
        "coding": [
          {
            "system": "http://snomed.info/sct",
            "code": "46635009",
            "display": "Diabetes mellitus type 1 (disorder)"
          }
        ]
      },
      "exclude": false,
      "description": "Diagnosis of T1DM based on the World Health Organization (WHO) diagnostic criteria",
      "method": [
        {
          "text": "based on the World Health Organization (WHO) diagnostic criteria"
        }
      ]
    },
    {
      "code": {
        "text": "Medication exposure"
      },
      "valueCodeableConcept": {
        "text": "Insulin therapy with multiple daily injection of long-acting insulin analog (either insulin glargine [U-100 or U-300] or insulin degludec [U-100]) and rapid-acting insulin analog (insulin lispro, insulin aspart, or insulin glulisine), or continuous subcutaneous insulin infusion (CSII)"
      },
      "exclude": false,
      "description": "Have been on the following daily insulin therapy for at least 1 year\n..1) multiple daily injection of long-acting insulin analog (either insulin glargine [U-100 or U-300] or insulin degludec [U-100]) and rapid-acting insulin analog (insulin lispro, insulin aspart, or insulin glulisine), or...2) continuous subcutaneous insulin infusion (CSII)",
      "durationDuration": {
        "value": 1,
        "comparator": ">=",
        "unit": "years",
        "system": "http://unitsofmeasure.org",
        "code": "a"
      }
    },
    {
      "code": {
        "coding": [
          {
            "system": "http://snomed.info/sct",
            "code": "397669002",
            "display": "Age"
          }
        ]
      },
      "valueRange": {
        "low": {
          "value": 18,
          "unit": "years",
          "system": "http://unitsofmeasure.org",
          "code": "a"
        },
        "high": {
          "value": 64,
          "unit": "years",
          "system": "http://unitsofmeasure.org",
          "code": "a"
        }
      },
      "exclude": false,
      "description": "Are between 18 and 64 years old at the time of informed consent",
      "timing": [
        {
          "contextCode": {
            "coding": [
              {
                "system": "http://snomed.info/sct",
                "code": "182771004",
                "display": "Informed consent for procedure"
              }
            ]
          },
          "offsetDuration": {
            "value": 0
          }
        }
      ]
    },
    {
      "code": {
        "coding": [
          {
            "system": "http://loinc.org",
            "code": "39156-5",
            "display": "Body mass index (BMI) [Ratio]"
          }
        ]
      },
      "valueRange": {
        "low": {
          "value": 18.5,
          "unit": "kilogram per square meter (kg/m2)",
          "system": "http://unitsofmeasure.org",
          "code": "kg/m2"
        },
        "high": {
          "value": 30,
          "unit": "kilogram per square meter (kg/m2)",
          "system": "http://unitsofmeasure.org",
          "code": "kg/m2"
        }
      },
      "exclude": false,
      "description": "Have a body mass index of 18.5 to 30.0 kg/m2 at the time of screening",
      "timing": [
        {
          "contextCode": {
            "text": "screening"
          },
          "offsetDuration": {
            "value": 0
          }
        }
      ]
    }
  ]
}