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Source1

{
  "resourceType": "EvidenceVariable",
  "id": "367890",
  "meta": {
    "versionId": "26",
    "lastUpdated": "2025-08-18T13:22:42.074Z",
    "profile": [
      "http://hl7.org/fhir/uv/ebm/StructureDefinition/variable-definition"
    ]
  },
  "language": "en",
  "text": {
    "status": "extensions",
    "div": "<!-- snip (see above) -->"
  },
  "contained": [
    {
      "resourceType": "Group",
      "id": "variable-definition",
      "meta": {
        "profile": [
          "http://hl7.org/fhir/uv/ebm/StructureDefinition/conceptual-cohort-definition"
        ]
      },
      "membership": "conceptual",
      "characteristic": [
        {
          "code": {
            "text": "defined by CodeableConcept"
          },
          "valueCodeableConcept": {
            "text": "Health-related Quality of Life"
          },
          "exclude": false,
          "timing": [
            {
              "text": "12 weeks"
            }
          ]
        }
      ]
    }
  ],
  "extension": [
    {
      "url": "http://hl7.org/fhir/uv/ebm/StructureDefinition/evidence-variable-handling-detail",
      "valueCodeableConcept": {
        "coding": [
          {
            "system": "https://fevir.net/resources/CodeSystem/179423",
            "code": "evidence-variable-handling-not-specified",
            "display": "Evidence variable handling not specified"
          }
        ]
      }
    },
    {
      "url": "http://hl7.org/fhir/uv/ebm/StructureDefinition/artifact-publication-status",
      "valueCodeableConcept": {
        "coding": [
          {
            "system": "http://terminology.hl7.org/CodeSystem/cited-artifact-status-type",
            "code": "active",
            "display": "Active"
          }
        ]
      }
    }
  ],
  "url": "https://fevir.net/resources/EvidenceVariable/367890",
  "identifier": [
    {
      "type": {
        "coding": [
          {
            "system": "http://terminology.hl7.org/CodeSystem/v2-0203",
            "code": "ACSN",
            "display": "Accession ID"
          }
        ],
        "text": "FEvIR Object Identifier"
      },
      "system": "https://fevir.net/FOI",
      "value": "367890",
      "assigner": {
        "display": "Computable Publishing LLC"
      }
    },
    {
      "type": {
        "text": "FEvIR Linking Identifier"
      },
      "system": "https://fevir.net/FLI",
      "value": "NCT03640312-secondaryOutcome-7",
      "assigner": {
        "display": "Computable Publishing LLC"
      }
    }
  ],
  "name": "Health_related_Quality_of_Life_NCT03640312",
  "title": "Health-related Quality of Life (NCT03640312)",
  "citeAs": "Health-related Quality of Life (NCT03640312) [Database Entry: FHIR EvidenceVariable Resource]. Contributors: Computable Publishing®: ClinicalTrials.gov-to-FEvIR Converter [Authors/Creators]. In: Fast Evidence Interoperability Resources (FEvIR) Platform, FOI 367890. Revised 2025-08-18. Available at: https://fevir.net/resources/EvidenceVariable/367890. Computable resource at: https://fevir.net/resources/EvidenceVariable/367890#json.",
  "status": "active",
  "author": [
    {
      "name": "Computable Publishing®: ClinicalTrials.gov-to-FEvIR Converter"
    }
  ],
  "publisher": "Computable Publishing LLC",
  "contact": [
    {
      "telecom": [
        {
          "system": "email",
          "value": "support@computablepublishing.com"
        }
      ]
    }
  ],
  "description": "Mean change (from baseline) in health-related quality of life using Patient-Reported Outcomes Measurement Information System (PROMIS) Global Health instrument. PROMIS Global Health is a gauge of general health-care related quality of life. Possible PROMIS Global Physical Health and Global Mental Health scores range from 0-20, with 20 indicating best possible state of health. Raw scores are converted to T-scores to compare to a standardized population. A PROMIS T-score of 50 represents the mean of the population (SD = 10). Higher values here also indicate better health. A positive change in T score, as reported in this outcome measure, would represent an improvement in Global Physical Health or Global Mental Health at 12 weeks compared to baseline.",
  "copyright": "https://creativecommons.org/licenses/by-nc-sa/4.0/",
  "definition": {
    "reference": {
      "reference": "#variable-definition",
      "type": "Group"
    }
  },
  "handling": "extension"
}