FHIR IG analytics

Resources that use this resource

No resources found

Resources that this resource uses

No resources found

Narrative

Note: links and images are rebased to the (stated) source

Source1

{
  "resourceType": "Evidence",
  "id": "47762",
  "meta": {
    "versionId": "14",
    "lastUpdated": "2023-12-06T18:56:02.603Z",
    "profile": [
      "http://hl7.org/fhir/uv/ebm/StructureDefinition/comparative-evidence",
      "http://hl7.org/fhir/uv/ebm/StructureDefinition/single-study-evidence"
    ]
  },
  "language": "en",
  "text": {
    "status": "extensions",
    "div": "<!-- snip (see above) -->"
  },
  "extension": [
    {
      "url": "http://hl7.org/fhir/uv/ebm/StructureDefinition/artifact-publication-status",
      "valueCodeableConcept": {
        "coding": [
          {
            "system": "http://terminology.hl7.org/CodeSystem/cited-artifact-status-type",
            "code": "active",
            "display": "Active"
          }
        ]
      }
    }
  ],
  "url": "https://fevir.net/resources/Evidence/47762",
  "identifier": [
    {
      "type": {
        "coding": [
          {
            "system": "http://terminology.hl7.org/CodeSystem/v2-0203",
            "code": "ACSN",
            "display": "Accession ID"
          }
        ],
        "text": "FEvIR Object Identifier"
      },
      "system": "https://fevir.net/FOI",
      "value": "47762",
      "assigner": {
        "display": "Computable Publishing LLC"
      }
    }
  ],
  "name": "ComparativeEvidence_Mean_difference_in_HbA1c_between_Surgery_and_Medical_Lifestyle_groups_in_Ikramuddin_2015",
  "title": "ComparativeEvidence: Mean difference in HbA1c between Surgery and Medical/Lifestyle groups in Ikramuddin 2015",
  "citeAs": "ComparativeEvidence: Mean difference in HbA1c between Surgery and Medical/Lifestyle groups in Ikramuddin 2015 [Evidence]. Contributors: In: Fast Evidence Interoperability Resources (FEvIR) Platform, FOI 47762. Revised 2022-05-29. Available at: https://fevir.net/resources/Evidence/47762. Computable resource at: https://fevir.net/resources/Evidence/47762.",
  "status": "active",
  "date": "2022-05-29T11:01:10.770Z",
  "author": [
    {
      "name": "Brian S. Alper"
    }
  ],
  "publisher": "Computable Publishing LLC",
  "contact": [
    {
      "telecom": [
        {
          "system": "email",
          "value": "support@computablepublishing.com"
        }
      ]
    }
  ],
  "useContext": [
    {
      "code": {
        "system": "https://fevir.net/resources/CodeSystem/179423",
        "code": "evidence-communication",
        "display": "Evidence Communication"
      },
      "valueCodeableConcept": {
        "coding": [
          {
            "system": "https://fevir.net/resources/CodeSystem/179423",
            "code": "ComparativeEvidence",
            "display": "ComparativeEvidence"
          }
        ]
      }
    },
    {
      "code": {
        "system": "https://fevir.net/resources/CodeSystem/179423",
        "code": "evidence-communication",
        "display": "Evidence Communication"
      },
      "valueCodeableConcept": {
        "coding": [
          {
            "system": "https://fevir.net/resources/CodeSystem/179423",
            "code": "SingleStudyEvidence",
            "display": "SingleStudyEvidence"
          }
        ]
      }
    }
  ],
  "copyright": "https://creativecommons.org/licenses/by-nc-sa/4.0/",
  "relatesTo": [
    {
      "extension": [
        {
          "url": "http://hl7.org/fhir/uv/ebm/StructureDefinition/relatesto-classifier",
          "valueCodeableConcept": {
            "text": "data source"
          }
        }
      ],
      "type": "derived-from",
      "targetAttachment": {
        "url": "https://diabetesjournals.org/care/article/39/6/861/29305/Metabolic-Surgery-in-the-Treatment-Algorithm-for",
        "title": "Figure 2C Metabolic Surgery in the Treatment Algorithm for Type 2 Diabetes: A Joint Statement by International Diabetes Organizations [Journal Article]. Contributors: Francesco Rubino, David M Nathan, Robert H Eckel, Philip R Schauer, K George M M Alberti, Paul Z Zimmet, Stefano Del Prato, Linong Ji, Shaukat M Sadikot, William H Herman, Stephanie A Amiel, Lee M Kaplan, Gaspar Taroncher-Oldenburg, David E Cummings, Delegates of the 2nd Diabetes Surgery Summit. In: Diabetes care, PMID 27222544. Published June 2016. Available at: https://pubmed.ncbi.nlm.nih.gov/27222544/."
      }
    }
  ],
  "description": "Mean HbA1c at 24 months in Ikramuddin 2015 was 6.5% in Surgery group (n = 56) and 8.4% in Medical/Lifestyle group (n = 54), mean difference -1.90% (95% CI -2.78% to -1.02%)",
  "variableDefinition": [
    {
      "description": "110 patients aged 30-67 years with HbA1c of at least 8%, BMI between 30 and 39.9 and T2DM for at least 6 months",
      "variableRole": "population",
      "observed": {
        "type": "Group",
        "display": "Ikramuddin 2015 (Diabetes Surgery Study) Trial Enrollment Group"
      }
    },
    {
      "description": "Roux-en-Y gastric bypass vs. medical treatment (intensive lifestyle and medical management)",
      "variableRole": "exposure",
      "comparatorCategory": "Lifestyle-intensive medical management intervention based on the Diabetes Prevention Program and LookAHEAD trials for 2 years",
      "observed": {
        "reference": "EvidenceVariable/172481",
        "type": "EvidenceVariable",
        "display": "GroupAssignment: Roux-en-Y gastric bypass surgery vs. Lifestyle-intensive medical management intervention alone"
      }
    },
    {
      "description": "HbA1c at 24 months",
      "variableRole": "outcome",
      "observed": {
        "reference": "EvidenceVariable/173246",
        "type": "EvidenceVariable",
        "display": "OutcomeVariable: HbA1c at 24 months"
      }
    }
  ],
  "synthesisType": [
    {
      "coding": [
        {
          "system": "http://terminology.hl7.org/CodeSystem/synthesis-type",
          "code": "NotApplicable",
          "display": "not applicable"
        }
      ]
    }
  ],
  "studyDesign": [
    {
      "coding": [
        {
          "system": "https://fevir.net/sevco",
          "code": "SEVCO:01003",
          "display": "randomized assignment"
        }
      ]
    }
  ],
  "statistic": [
    {
      "description": "mean difference -1.90% (95% CI -2.78% to -1.02%)",
      "note": [
        {
          "text": "Mean HbA1c at 24 months in Ikramuddin 2015 was 6.5% in Surgery group (n = 56) and 8.4% in Medical/Lifestyle group (n = 54)"
        }
      ],
      "statisticType": {
        "coding": [
          {
            "system": "http://terminology.hl7.org/CodeSystem/statistic-type",
            "code": "0000457",
            "display": "Mean Difference"
          }
        ]
      },
      "quantity": {
        "value": -1.9,
        "unit": "%",
        "system": "http://unitsofmeasure.org",
        "code": "%"
      },
      "sampleSize": {
        "numberOfParticipants": 110,
        "knownDataCount": 110
      },
      "attributeEstimate": [
        {
          "description": "95% CI -2.78% to -1.02%",
          "type": {
            "coding": [
              {
                "system": "http://terminology.hl7.org/CodeSystem/attribute-estimate-type",
                "code": "C53324",
                "display": "Confidence interval"
              }
            ]
          },
          "level": 0.95,
          "range": {
            "low": {
              "value": -2.78,
              "unit": "%",
              "system": "http://unitsofmeasure.org",
              "code": "%"
            },
            "high": {
              "value": -1.02,
              "unit": "%",
              "system": "http://unitsofmeasure.org",
              "code": "%"
            }
          }
        }
      ]
    }
  ]
}