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Source1

{
  "resourceType": "Evidence",
  "id": "397483",
  "meta": {
    "versionId": "4",
    "lastUpdated": "2025-09-13T18:20:05.948Z"
  },
  "language": "en",
  "text": {
    "status": "generated",
    "div": "<!-- snip (see above) -->"
  },
  "url": "https://fevir.net/resources/Evidence/397483",
  "identifier": [
    {
      "type": {
        "coding": [
          {
            "system": "http://terminology.hl7.org/CodeSystem/v2-0203",
            "code": "ACSN",
            "display": "Accession ID"
          }
        ],
        "text": "FEvIR Object Identifier"
      },
      "system": "https://fevir.net/FOI",
      "value": "397483",
      "assigner": {
        "display": "Computable Publishing LLC"
      }
    }
  ],
  "name": "Evidence_for_Results_for_Systolic_blood_pressure_at_12_weeks_in_GroupAssignment_Quadpill_vs_Candesartan",
  "title": "Evidence for Results for Systolic blood pressure at 12 weeks in GroupAssignment: Quadpill vs. Candesartan",
  "citeAs": "Evidence for Results for Systolic blood pressure at 12 weeks in GroupAssignment: Quadpill vs. Candesartan [Database Entry: FHIR Evidence Resource]. Contributors: Brian S. Alper, MD, MSPH [Authors/Creators]. In: Fast Evidence Interoperability Resources (FEvIR) Platform, FOI 397483. Revised 2025-09-13. Available at: https://fevir.net/resources/Evidence/397483. Computable resource at: https://fevir.net/resources/Evidence/397483#json.",
  "status": "active",
  "author": [
    {
      "name": "Brian S. Alper, MD, MSPH"
    }
  ],
  "publisher": "Computable Publishing LLC",
  "contact": [
    {
      "telecom": [
        {
          "system": "email",
          "value": "support@computablepublishing.com"
        }
      ]
    }
  ],
  "copyright": "https://creativecommons.org/licenses/by-nc-sa/4.0/",
  "relatesTo": [
    {
      "type": "part-of",
      "targetReference": {
        "reference": "Composition/375280",
        "type": "Composition",
        "display": "Outcome Measure Report for QUARTET USA Trial"
      }
    }
  ],
  "description": "This Evidence Resource is referenced in an example for the EBMonFHIR Implementation Guide.",
  "variableDefinition": [
    {
      "variableRole": "population",
      "observed": {
        "display": "the study group"
      }
    },
    {
      "variableRole": "exposure",
      "observed": {
        "reference": "EvidenceVariable/375183",
        "type": "EvidenceVariable",
        "display": "GroupAssignment: Quadpill vs. Candesartan"
      }
    },
    {
      "variableRole": "outcome",
      "observed": {
        "reference": "EvidenceVariable/375185",
        "type": "EvidenceVariable",
        "display": "Systolic blood pressure at 12 weeks"
      }
    }
  ],
  "statistic": [
    {
      "statisticType": {
        "coding": [
          {
            "system": "https://fevir.net/sevco",
            "code": "STATO:0000457",
            "display": "difference in means"
          }
        ]
      },
      "quantity": {
        "value": -4.5,
        "unit": "mm Hg"
      },
      "sampleSize": {
        "extension": [
          {
            "url": "http://hl7.org/fhir/uv/ebm/StructureDefinition/number-analyzed",
            "valueUnsignedInt": 60
          }
        ],
        "numberOfParticipants": 62,
        "knownDataCount": 53
      },
      "attributeEstimate": [
        {
          "type": {
            "coding": [
              {
                "system": "https://fevir.net/sevco",
                "code": "STATO:0000196",
                "display": "confidence interval"
              }
            ]
          },
          "level": 0.95,
          "range": {
            "low": {
              "value": -10.82,
              "unit": "mm Hg"
            },
            "high": {
              "value": 1.32,
              "unit": "mm Hg"
            }
          }
        },
        {
          "type": {
            "coding": [
              {
                "system": "https://fevir.net/sevco",
                "code": "STATO:0000700",
                "display": "p-value"
              }
            ]
          },
          "quantity": {
            "value": 0.123
          }
        }
      ]
    }
  ]
}