FHIR IG analytics| Package | hl7.fhir.uv.ebm |
| Resource Type | Composition |
| Id | Composition-397488.json |
| FHIR Version | R6 |
No resources found
No resources found
Note: links and images are rebased to the (stated) source
Outcome | Sample Size | Result Without Treatment | Result With Treatment (Observed) | Result With Treatment (Calculated) | Effect Estimate | Certainty of Evidence | What this means |
|---|---|---|---|---|---|---|---|
Systolic blood pressure at 12 weeks | 62 participants, 60 analyzed, 53 without missing data | [No summary statement.] | [No summary statement.] | [No summary statement.] | difference in means -4.5 mm Hg (95% confidence interval -10.82 mm Hg to 1.32 mm Hg) | [No summary statement.] | [No summary statement.] |
Diastolic blood pressure at 12 weeks | 62 participants, 60 analyzed, 53 without missing data | [No summary statement.] | [No summary statement.] | [Not a proportion.] | difference in means -4.92 mm Hg (95% confidence interval -8.58 mm Hg to 0.27 mm Hg) | [No summary statement.] | [No summary statement.] |
Medication Adherence at 12 weeks | 62 participants, 53 without missing data | 70% | 65.6% | 46.33% | odds ratio 0.37 (95% confidence interval 0.19 to 2.08) | [No summary statement.] | [No summary statement.] |
Hypertension Control at 12 weeks | 62 participants, 60 analyzed, 53 without missing data | 54.17% | 65.52% | 77.11% | odds ratio 2.85 (95% confidence interval 0.94 to 8.59) | [No summary statement.] | [No summary statement.] |
Add-on Amlodipine at 6 weeks | 62 participants, 60 analyzed, 62 without missing data, 22 events | 53.33% | 18.75% | 51.25% | odds ratio 0.92 (95% confidence interval 0.02 to 0.41) | [No summary statement.] | [No summary statement.] |
Adverse event free and hypertension control at 12 weeks | 62 participants, 53 analyzed, 53 without missing data, 13 events | 33.33% | 17.24% | 29.33% | odds ratio 0.83 (95% confidence interval 0.22 to 3.16) | [No summary statement.] | [No summary statement.] |
FHIR
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{
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"status": "empty",
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"section": [
{
"title": "Results for Systolic blood pressure at 12 weeks",
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"div": "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p>Systolic blood pressure at 12 weeks</p></div>"
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"div": "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p>62 participants, 60 analyzed, 53 without missing data</p></div>"
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{
"reference": "Evidence/397483",
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"div": "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p>[Not a proportion.]</p></div>"
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"entry": [
{
"reference": "Evidence/375628",
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{
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"text": "result with intervention with calculated value derived from the control group and effect estimate"
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"text": {
"status": "empty",
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{
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"text": {
"status": "generated",
"div": "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p>difference in means -4.5 mm Hg (95% confidence interval -10.82 mm Hg to 1.32 mm Hg)</p></div>"
},
"entry": [
{
"reference": "Evidence/397483",
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"text": {
"status": "empty",
"div": "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p>[No certainty rating found.]</p></div>"
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"entry": [
{
"reference": "Evidence/397483",
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"title": "Assertion",
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"text": {
"status": "empty",
"div": "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p>[No assertion provided.]</p></div>"
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"entry": [
{
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}
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{
"title": "Results for Diastolic blood pressure at 12 weeks",
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"focus": {
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"status": "generated",
"div": "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p>Diastolic blood pressure at 12 weeks</p></div>"
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{
"reference": "EvidenceVariable/375186",
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]
},
{
"title": "Sample Size",
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"coding": [
{
"system": "https://fevir.net/resources/CodeSystem/179423",
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]
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"status": "generated",
"div": "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p>62 participants, 60 analyzed, 53 without missing data</p></div>"
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"entry": [
{
"reference": "Evidence/397482",
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{
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{
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]
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"text": {
"status": "empty",
"div": "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p>[Not a proportion.]</p></div>"
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"entry": [
{
"reference": "Evidence/375932",
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{
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{
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"text": {
"status": "empty",
"div": "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p>[Not a proportion.]</p></div>"
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"entry": [
{
"reference": "Evidence/375629",
"type": "Evidence",
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{
"title": "Result With Treatment--Derived",
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{
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"text": "result with intervention with calculated value derived from the control group and effect estimate"
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"text": {
"status": "empty",
"div": "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p>[No data.]</p></div>"
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{
"title": "Effect Estimate",
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{
"system": "https://fevir.net/resources/CodeSystem/179423",
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},
"text": {
"status": "generated",
"div": "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p>difference in means -4.92 mm Hg (95% confidence interval -8.58 mm Hg to 0.27 mm Hg)</p></div>"
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{
"reference": "Evidence/397482",
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"text": {
"status": "empty",
"div": "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p>[No certainty rating found.]</p></div>"
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"entry": [
{
"reference": "Evidence/397482",
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"title": "Assertion",
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"text": {
"status": "empty",
"div": "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p>[No assertion provided.]</p></div>"
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"entry": [
{
"reference": "Evidence/397482",
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}
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},
{
"title": "Results for Medication Adherence at 12 weeks",
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"focus": {
"reference": "EvidenceVariable/375201",
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"text": {
"status": "empty",
"div": "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p>[No data.]</p></div>"
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"section": [
{
"title": "Outcome Measure",
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{
"system": "https://fevir.net/resources/CodeSystem/179423",
"code": "outcome-measure",
"display": "Outcome Measure"
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"text": {
"status": "generated",
"div": "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p>Medication Adherence at 12 weeks</p></div>"
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"entry": [
{
"reference": "EvidenceVariable/375201",
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{
"title": "Sample Size",
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"coding": [
{
"system": "https://fevir.net/resources/CodeSystem/179423",
"code": "sample-size",
"display": "Sample Size"
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]
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"text": {
"status": "generated",
"div": "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p>62 participants, 53 without missing data</p></div>"
},
"entry": [
{
"reference": "Evidence/397481",
"type": "Evidence",
"display": "Evidence for Results for Medication Adherence at 12 weeks in GroupAssignment: Quadpill vs. Candesartan"
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{
"title": "Result Without Treatment",
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"coding": [
{
"system": "https://fevir.net/resources/CodeSystem/179423",
"code": "result-with-comparator-alone",
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]
},
"text": {
"status": "generated",
"div": "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p>70%</p></div>"
},
"entry": [
{
"reference": "Evidence/379724",
"type": "Evidence",
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{
"title": "Result With Treatment--Observed",
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"coding": [
{
"system": "https://fevir.net/resources/CodeSystem/179423",
"code": "result-with-intervention-alone",
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},
"text": {
"status": "generated",
"div": "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p>65.6%</p></div>"
},
"entry": [
{
"reference": "Evidence/379723",
"type": "Evidence",
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{
"title": "Result With Treatment--Derived",
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{
"system": "https://fevir.net/resources/CodeSystem/179423",
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],
"text": "result with intervention with calculated value derived from the control group and effect estimate"
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"text": {
"status": "empty",
"div": "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p>[No data.]</p></div>"
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},
{
"title": "Effect Estimate",
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{
"system": "https://fevir.net/resources/CodeSystem/179423",
"code": "result-with-intervention-vs-comparator",
"display": "Result with intervention vs. comparator"
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]
},
"text": {
"status": "generated",
"div": "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p>odds ratio 0.37 (95% confidence interval 0.19 to 2.08)</p></div>"
},
"entry": [
{
"reference": "Evidence/397481",
"type": "Evidence",
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},
{
"title": "Certainty of Evidence",
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{
"system": "https://fevir.net/resources/CodeSystem/179423",
"code": "certainty-of-evidence",
"display": "Certainty of Evidence"
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]
},
"text": {
"status": "empty",
"div": "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p>[No certainty rating found.]</p></div>"
},
"entry": [
{
"reference": "Evidence/397481",
"type": "Evidence",
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]
},
{
"title": "Assertion",
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"coding": [
{
"system": "https://fevir.net/resources/CodeSystem/179423",
"code": "assertion",
"display": "Assertion"
}
]
},
"text": {
"status": "empty",
"div": "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p>[No assertion provided.]</p></div>"
},
"entry": [
{
"reference": "Evidence/397481",
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}
]
},
{
"title": "Results for Hypertension Control at 12 weeks",
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{
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{
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"coding": [
{
"system": "https://fevir.net/resources/CodeSystem/179423",
"code": "outcome-measure",
"display": "Outcome Measure"
}
]
},
"text": {
"status": "generated",
"div": "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p>Hypertension Control at 12 weeks</p></div>"
},
"entry": [
{
"reference": "EvidenceVariable/375202",
"type": "EvidenceVariable",
"display": "Hypertension Control at 12 weeks"
}
]
},
{
"title": "Sample Size",
"code": {
"coding": [
{
"system": "https://fevir.net/resources/CodeSystem/179423",
"code": "sample-size",
"display": "Sample Size"
}
]
},
"text": {
"status": "generated",
"div": "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p>62 participants, 60 analyzed, 53 without missing data</p></div>"
},
"entry": [
{
"reference": "Evidence/397480",
"type": "Evidence",
"display": "Evidence for Results for Hypertension Control at 12 weeks in GroupAssignment: Quadpill vs. Candesartan"
}
]
},
{
"title": "Result Without Treatment",
"code": {
"coding": [
{
"system": "https://fevir.net/resources/CodeSystem/179423",
"code": "result-with-comparator-alone",
"display": "Result with comparator alone"
}
]
},
"text": {
"status": "generated",
"div": "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p>54.17%</p></div>"
},
"entry": [
{
"reference": "Evidence/379737",
"type": "Evidence",
"display": "Evidence for Results for Hypertension Control at 12 weeks in QUARTET USA Trial Control Group"
}
]
},
{
"title": "Result With Treatment--Observed",
"code": {
"coding": [
{
"system": "https://fevir.net/resources/CodeSystem/179423",
"code": "result-with-intervention-alone",
"display": "Result with intervention alone"
}
]
},
"text": {
"status": "generated",
"div": "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p>65.52%</p></div>"
},
"entry": [
{
"reference": "Evidence/379736",
"type": "Evidence",
"display": "Evidence for Results for Hypertension Control at 12 weeks in QUARTET USA Trial Quadpill group"
}
]
},
{
"title": "Result With Treatment--Derived",
"code": {
"coding": [
{
"system": "https://fevir.net/resources/CodeSystem/179423",
"code": "result-with-intervention-alone-calculated",
"display": "Result with intervention alone (calculated)"
}
],
"text": "result with intervention with calculated value derived from the control group and effect estimate"
},
"text": {
"status": "empty",
"div": "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p>[No data.]</p></div>"
}
},
{
"title": "Effect Estimate",
"code": {
"coding": [
{
"system": "https://fevir.net/resources/CodeSystem/179423",
"code": "result-with-intervention-vs-comparator",
"display": "Result with intervention vs. comparator"
}
]
},
"text": {
"status": "generated",
"div": "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p>odds ratio 2.85 (95% confidence interval 0.94 to 8.59)</p></div>"
},
"entry": [
{
"reference": "Evidence/397480",
"type": "Evidence",
"display": "Evidence for Results for Hypertension Control at 12 weeks in GroupAssignment: Quadpill vs. Candesartan"
}
]
},
{
"title": "Certainty of Evidence",
"code": {
"coding": [
{
"system": "https://fevir.net/resources/CodeSystem/179423",
"code": "certainty-of-evidence",
"display": "Certainty of Evidence"
}
]
},
"text": {
"status": "empty",
"div": "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p>[No certainty rating found.]</p></div>"
},
"entry": [
{
"reference": "Evidence/397480",
"type": "Evidence",
"display": "Evidence for Results for Hypertension Control at 12 weeks in GroupAssignment: Quadpill vs. Candesartan"
}
]
},
{
"title": "Assertion",
"code": {
"coding": [
{
"system": "https://fevir.net/resources/CodeSystem/179423",
"code": "assertion",
"display": "Assertion"
}
]
},
"text": {
"status": "empty",
"div": "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p>[No assertion provided.]</p></div>"
},
"entry": [
{
"reference": "Evidence/397480",
"type": "Evidence",
"display": "Evidence for Results for Hypertension Control at 12 weeks in GroupAssignment: Quadpill vs. Candesartan"
}
]
}
]
},
{
"title": "Results for Add-on Amlodipine at 6 weeks",
"code": {
"coding": [
{
"system": "https://fevir.net/resources/CodeSystem/179423",
"code": "summary-of-findings-entry-for-a-single-outcome",
"display": "Summary of findings entry for a single outcome"
}
]
},
"focus": {
"reference": "EvidenceVariable/375203",
"type": "EvidenceVariable",
"display": "Add-on Amlodipine at 6 weeks"
},
"section": [
{
"title": "Outcome Measure",
"code": {
"coding": [
{
"system": "https://fevir.net/resources/CodeSystem/179423",
"code": "outcome-measure",
"display": "Outcome Measure"
}
]
},
"text": {
"status": "generated",
"div": "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p>Add-on Amlodipine at 6 weeks</p></div>"
},
"entry": [
{
"reference": "EvidenceVariable/375203",
"type": "EvidenceVariable",
"display": "Add-on Amlodipine at 6 weeks"
}
]
},
{
"title": "Sample Size",
"code": {
"coding": [
{
"system": "https://fevir.net/resources/CodeSystem/179423",
"code": "sample-size",
"display": "Sample Size"
}
]
},
"text": {
"status": "generated",
"div": "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p>62 participants, 60 analyzed, 62 without missing data, 22 events</p></div>"
},
"entry": [
{
"reference": "Evidence/397479",
"type": "Evidence",
"display": "Evidence for Results for Add-on Amlodipine at 6 weeks in GroupAssignment: Quadpill vs. Candesartan"
}
]
},
{
"title": "Result Without Treatment",
"code": {
"coding": [
{
"system": "https://fevir.net/resources/CodeSystem/179423",
"code": "result-with-comparator-alone",
"display": "Result with comparator alone"
}
]
},
"text": {
"status": "generated",
"div": "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p>53.33%</p></div>"
},
"entry": [
{
"reference": "Evidence/379740",
"type": "Evidence",
"display": "Evidence for Results for Add-on Amlodipine at 6 weeks in QUARTET USA Trial Control Group"
}
]
},
{
"title": "Result With Treatment--Observed",
"code": {
"coding": [
{
"system": "https://fevir.net/resources/CodeSystem/179423",
"code": "result-with-intervention-alone",
"display": "Result with intervention alone"
}
]
},
"text": {
"status": "generated",
"div": "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p>18.75%</p></div>"
},
"entry": [
{
"reference": "Evidence/379739",
"type": "Evidence",
"display": "Evidence for Results for Add-on Amlodipine at 6 weeks in QUARTET USA Trial Quadpill group"
}
]
},
{
"title": "Result With Treatment--Derived",
"code": {
"coding": [
{
"system": "https://fevir.net/resources/CodeSystem/179423",
"code": "result-with-intervention-alone-calculated",
"display": "Result with intervention alone (calculated)"
}
],
"text": "result with intervention with calculated value derived from the control group and effect estimate"
},
"text": {
"status": "empty",
"div": "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p>[No data.]</p></div>"
}
},
{
"title": "Effect Estimate",
"code": {
"coding": [
{
"system": "https://fevir.net/resources/CodeSystem/179423",
"code": "result-with-intervention-vs-comparator",
"display": "Result with intervention vs. comparator"
}
]
},
"text": {
"status": "generated",
"div": "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p>odds ratio 0.92 (95% confidence interval 0.02 to 0.41)</p></div>"
},
"entry": [
{
"reference": "Evidence/397479",
"type": "Evidence",
"display": "Evidence for Results for Add-on Amlodipine at 6 weeks in GroupAssignment: Quadpill vs. Candesartan"
}
]
},
{
"title": "Certainty of Evidence",
"code": {
"coding": [
{
"system": "https://fevir.net/resources/CodeSystem/179423",
"code": "certainty-of-evidence",
"display": "Certainty of Evidence"
}
]
},
"text": {
"status": "empty",
"div": "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p>[No certainty rating found.]</p></div>"
},
"entry": [
{
"reference": "Evidence/397479",
"type": "Evidence",
"display": "Evidence for Results for Add-on Amlodipine at 6 weeks in GroupAssignment: Quadpill vs. Candesartan"
}
]
},
{
"title": "Assertion",
"code": {
"coding": [
{
"system": "https://fevir.net/resources/CodeSystem/179423",
"code": "assertion",
"display": "Assertion"
}
]
},
"text": {
"status": "empty",
"div": "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p>[No assertion provided.]</p></div>"
},
"entry": [
{
"reference": "Evidence/397479",
"type": "Evidence",
"display": "Evidence for Results for Add-on Amlodipine at 6 weeks in GroupAssignment: Quadpill vs. Candesartan"
}
]
}
]
},
{
"title": "Results for Adverse event free and hypertension control at 12 weeks",
"code": {
"coding": [
{
"system": "https://fevir.net/resources/CodeSystem/179423",
"code": "summary-of-findings-entry-for-a-single-outcome",
"display": "Summary of findings entry for a single outcome"
}
]
},
"focus": {
"reference": "EvidenceVariable/375278",
"type": "EvidenceVariable",
"display": "Adverse event free and hypertension control at 12 weeks"
},
"section": [
{
"title": "Outcome Measure",
"code": {
"coding": [
{
"system": "https://fevir.net/resources/CodeSystem/179423",
"code": "outcome-measure",
"display": "Outcome Measure"
}
]
},
"text": {
"status": "generated",
"div": "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p>Adverse event free and hypertension control at 12 weeks</p></div>"
},
"entry": [
{
"reference": "EvidenceVariable/375278",
"type": "EvidenceVariable",
"display": "Adverse event free and hypertension control at 12 weeks"
}
]
},
{
"title": "Sample Size",
"code": {
"coding": [
{
"system": "https://fevir.net/resources/CodeSystem/179423",
"code": "sample-size",
"display": "Sample Size"
}
]
},
"text": {
"status": "generated",
"div": "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p>62 participants, 53 analyzed, 53 without missing data, 13 events</p></div>"
},
"entry": [
{
"reference": "Evidence/397478",
"type": "Evidence",
"display": "Evidence for Results for Adverse event free and hypertension control at 12 weeks in GroupAssignment: Quadpill vs. Candesartan"
}
]
},
{
"title": "Result Without Treatment",
"code": {
"coding": [
{
"system": "https://fevir.net/resources/CodeSystem/179423",
"code": "result-with-comparator-alone",
"display": "Result with comparator alone"
}
]
},
"text": {
"status": "generated",
"div": "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p>33.33%</p></div>"
},
"entry": [
{
"reference": "Evidence/379743",
"type": "Evidence",
"display": "Evidence for Results for Adverse event free and hypertension control at 12 weeks in QUARTET USA Trial Control Group"
}
]
},
{
"title": "Result With Treatment--Observed",
"code": {
"coding": [
{
"system": "https://fevir.net/resources/CodeSystem/179423",
"code": "result-with-intervention-alone",
"display": "Result with intervention alone"
}
]
},
"text": {
"status": "generated",
"div": "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p>17.24%</p></div>"
},
"entry": [
{
"reference": "Evidence/379742",
"type": "Evidence",
"display": "Evidence for Results for Adverse event free and hypertension control at 12 weeks in QUARTET USA Trial Quadpill group"
}
]
},
{
"title": "Result With Treatment--Derived",
"code": {
"coding": [
{
"system": "https://fevir.net/resources/CodeSystem/179423",
"code": "result-with-intervention-alone-calculated",
"display": "Result with intervention alone (calculated)"
}
],
"text": "result with intervention with calculated value derived from the control group and effect estimate"
},
"text": {
"status": "empty",
"div": "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p>[No data.]</p></div>"
}
},
{
"title": "Effect Estimate",
"code": {
"coding": [
{
"system": "https://fevir.net/resources/CodeSystem/179423",
"code": "result-with-intervention-vs-comparator",
"display": "Result with intervention vs. comparator"
}
]
},
"text": {
"status": "generated",
"div": "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p>odds ratio 0.83 (95% confidence interval 0.22 to 3.16)</p></div>"
},
"entry": [
{
"reference": "Evidence/397478",
"type": "Evidence",
"display": "Evidence for Results for Adverse event free and hypertension control at 12 weeks in GroupAssignment: Quadpill vs. Candesartan"
}
]
},
{
"title": "Certainty of Evidence",
"code": {
"coding": [
{
"system": "https://fevir.net/resources/CodeSystem/179423",
"code": "certainty-of-evidence",
"display": "Certainty of Evidence"
}
]
},
"text": {
"status": "empty",
"div": "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p>[No certainty rating found.]</p></div>"
},
"entry": [
{
"reference": "Evidence/397478",
"type": "Evidence",
"display": "Evidence for Results for Adverse event free and hypertension control at 12 weeks in GroupAssignment: Quadpill vs. Candesartan"
}
]
},
{
"title": "Assertion",
"code": {
"coding": [
{
"system": "https://fevir.net/resources/CodeSystem/179423",
"code": "assertion",
"display": "Assertion"
}
]
},
"text": {
"status": "empty",
"div": "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p>[No assertion provided.]</p></div>"
},
"entry": [
{
"reference": "Evidence/397478",
"type": "Evidence",
"display": "Evidence for Results for Adverse event free and hypertension control at 12 weeks in GroupAssignment: Quadpill vs. Candesartan"
}
]
}
]
}
]
}
]
}