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Source1

{
  "resourceType": "CodeSystem",
  "id": "moleculardefinition-strand",
  "meta": {
    "lastUpdated": "2026-03-23T00:00:00Z",
    "profile": [
      "http://hl7.org/fhir/StructureDefinition/shareablecodesystem"
    ]
  },
  "text": {
    "status": "generated",
    "div": "<!-- snip (see above) -->"
  },
  "extension": [
    {
      "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-wg",
      "valueCode": "cg"
    },
    {
      "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status",
      "valueCode": "informative"
    },
    {
      "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fmm",
      "valueInteger": 0
    }
  ],
  "url": "http://hl7.org/fhir/uv/cg-incubator/CodeSystem/moleculardefinition-strand",
  "identifier": [
    {
      "system": "urn:ietf:rfc:3986",
      "value": "urn:oid:2.16.840.1.113883.4.642.4.3006"
    }
  ],
  "version": "0.1.0-ci-build",
  "name": "MolecularDefinitionStrand",
  "title": "Molecular Definition Strand CodeSystem",
  "status": "draft",
  "experimental": true,
  "date": "2026-03-23",
  "publisher": "HL7 International / Clinical Genomics",
  "contact": [
    {
      "name": "HL7 International / Clinical Genomics",
      "telecom": [
        {
          "system": "url",
          "value": "http://www.hl7.org/Special/committees/clingenomics"
        },
        {
          "system": "email",
          "value": "clingenomics@lists.hl7.org"
        }
      ]
    }
  ],
  "description": "The strand orientation of a sequenceLocation. Orientation of molecular sequences, indicating directionality for nucleotides (5' to 3' or 3' to 5') or amino acids (N to C terminus).",
  "jurisdiction": [
    {
      "coding": [
        {
          "system": "http://unstats.un.org/unsd/methods/m49/m49.htm",
          "code": "001",
          "display": "World"
        }
      ]
    }
  ],
  "caseSensitive": true,
  "valueSet": "http://hl7.org/fhir/uv/cg-incubator/ValueSet/moleculardefinition-strand",
  "content": "complete",
  "concept": [
    {
      "code": "forward",
      "display": "Forward strand",
      "definition": "5' to 3' for nucleotides or N-to-C for amino acids; also known as the positive/plus/sense/Watson strand. Single stranded sequences are conventionally represented in the forward direction."
    },
    {
      "code": "reverse",
      "display": "Reverse strand",
      "definition": "3' to 5' orientation; also known as the negative/minus/antisense/Crick strand. Applicable only to double stranded sequences."
    }
  ]
}