FHIR IG analytics| Package | hl7.fhir.us.uscdi-scd |
| Resource Type | StructureDefinition |
| Id | StructureDefinition-scd-transfusion-antigen-match.json |
| FHIR Version | R4 |
| Source | https://build.fhir.org/ig/hlnconsulting/uscdi-scd-ig/StructureDefinition-scd-transfusion-antigen-match.html |
| URL | http://hl7.org/fhir/us/uscdi-scd/StructureDefinition/scd-transfusion-antigen-match |
| Version | 0.1.0 |
| Status | active |
| Date | 2026-09-11T00:10:30+00:00 |
| Name | SCDTransfusionAntigenMatchExtension |
| Title | SCD Transfusion Red Cell Antigen Match Profile |
| Realm | us |
| Authority | hl7 |
| Description | Documents the red cell antigen matching criteria that were applied in selecting a blood product for transfusion in a patient with Sickle Cell Disease. Extended antigen-matched transfusion — typically including C, c, E, e (Rh), K (Kell), Fya/Fyb (Duffy), and Jka/Jkb (Kidd) at minimum — significantly reduces the risk of alloimmunization in SCD patients on chronic transfusion therapy. This extension enables structured documentation of which antigens were matched for a given transfusion event. This extension SHALL be used on SCDBiologicallyDerivedProduct instances when extended antigen matching was performed. It MAY also be used on the SCDProcedure instance representing the transfusion to document the matching requirements specified in the order. |
| Type | Extension |
| Kind | complex-type |
No resources found
| ValueSet | ||
| hl7.fhir.us.uscdi-scd#current | scd-red-cell-antigen-vs | SCD Red Cell Antigen Value Set |
| Resource | Version |
|---|---|
| hl7.fhir.us.uscdi-scd#current:BiologicallyDerivedProduct/prbcs-antigen-matched-example | R4 |
Note: links and images are rebased to the (stated) source
Generated Narrative: StructureDefinition scd-transfusion-antigen-match
| Name | Flags | Card. | Type | Description & Constraints |
|---|---|---|---|---|
![]() | 0..* | Extension | Extension | |
![]() ![]() | Content/Rules for all slices | |||
![]() ![]() ![]() | S | 0..* | Extension | Specific antigen confirmed matched/negative |
![]() ![]() ![]() ![]() | 0..0 | Extension | ||
![]() ![]() ![]() ![]() | 1..1 | uri | "matchedAntigen" | |
![]() ![]() ![]() ![]() | 0..1 | CodeableConcept | Value of extension Binding: SCD Red Cell Antigen Value Set (extensible) | |
![]() ![]() ![]() | S | 0..1 | Extension | Antigen matching protocol used |
![]() ![]() ![]() ![]() | 0..0 | Extension | ||
![]() ![]() ![]() ![]() | 1..1 | uri | "matchingProtocol" | |
![]() ![]() ![]() ![]() | 0..1 | string | Value of extension | |
![]() ![]() | 1..1 | uri | "http://hl7.org/fhir/us/uscdi-scd/StructureDefinition/scd-transfusion-antigen-match" | |
![]() ![]() | 0..0 | Value of extension | ||
{
"resourceType": "StructureDefinition",
"id": "scd-transfusion-antigen-match",
"text": {
"status": "extensions",
"div": "<!-- snip (see above) -->"
},
"url": "http://hl7.org/fhir/us/uscdi-scd/StructureDefinition/scd-transfusion-antigen-match",
"version": "0.1.0",
"name": "SCDTransfusionAntigenMatchExtension",
"title": "SCD Transfusion Red Cell Antigen Match Profile",
"status": "active",
"experimental": false,
"date": "2026-09-11T00:10:30+00:00",
"publisher": "HL7 International / Public Health",
"contact": [
{
"name": "HL7 International / Public Health",
"telecom": [
{
"system": "url",
"value": "https://www.hl7.org/Special/committees/pher"
},
{
"system": "email",
"value": "pher@lists.HL7.org"
}
]
},
{
"name": "HL7 Public Health Work Group",
"telecom": [
{
"system": "url",
"value": "http://www.hl7.org/Special/committees/pher"
},
{
"system": "email",
"value": "pher@lists.HL7.org"
}
]
}
],
"description": "Documents the red cell antigen matching criteria that were applied in\nselecting a blood product for transfusion in a patient with Sickle Cell Disease.\n\nExtended antigen-matched transfusion — typically including C, c, E, e (Rh),\nK (Kell), Fya/Fyb (Duffy), and Jka/Jkb (Kidd) at minimum — significantly\nreduces the risk of alloimmunization in SCD patients on chronic transfusion\ntherapy. This extension enables structured documentation of which antigens\nwere matched for a given transfusion event.\n\nThis extension SHALL be used on SCDBiologicallyDerivedProduct instances when\nextended antigen matching was performed. It MAY also be used on the SCDProcedure\ninstance representing the transfusion to document the matching requirements\nspecified in the order.",
"jurisdiction": [
{
"coding": [
{
"system": "urn:iso:std:iso:3166",
"code": "US",
"display": "United States of America"
}
]
}
],
"fhirVersion": "4.0.1",
"mapping": [
{
"identity": "rim",
"uri": "http://hl7.org/v3",
"name": "RIM Mapping"
}
],
"kind": "complex-type",
"abstract": false,
"context": [
{
"type": "element",
"expression": "BiologicallyDerivedProduct"
},
{
"type": "element",
"expression": "Procedure"
}
],
"type": "Extension",
"baseDefinition": "http://hl7.org/fhir/StructureDefinition/Extension",
"derivation": "constraint",
"snapshot": {
"extension": [
{
"url": "http://hl7.org/fhir/tools/StructureDefinition/snapshot-base-version",
"valueString": "4.0.1"
}
],
"element": [
{
"id": "Extension",
"path": "Extension",
"short": "Extension",
"definition": "An Extension",
"min": 0,
"max": "*",
"base": {
"path": "Extension",
"min": 0,
"max": "*"
},
"condition": [
"ele-1"
],
"constraint": [
{
"key": "ele-1",
"severity": "error",
"human": "All FHIR elements must have a @value or children",
"expression": "hasValue() or (children().count() > id.count())",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element"
},
{
"key": "ext-1",
"severity": "error",
"human": "Must have either extensions or value[x], not both",
"expression": "extension.exists() != value.exists()",
"xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), 'value')])",
"source": "http://hl7.org/fhir/StructureDefinition/Extension"
}
],
"isModifier": false
},
{
"id": "Extension.id",
"path": "Extension.id",
"representation": [
"xmlAttr"
],
"short": "Unique id for inter-element referencing",
"definition": "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.",
"min": 0,
"max": "1",
"base": {
"path": "Element.id",
"min": 0,
"max": "1"
},
"type": [
{
"extension": [
{
"url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
"valueUrl": "string"
}
],
"code": "http://hl7.org/fhirpath/System.String"
}
],
"isModifier": false,
"isSummary": false,
"mapping": [
{
"identity": "rim",
"map": "n/a"
}
]
},
{
"id": "Extension.extension",
"path": "Extension.extension",
"slicing": {
"discriminator": [
{
"type": "value",
"path": "url"
}
],
"description": "Extensions are always sliced by (at least) url",
"rules": "open"
},
"short": "Additional content defined by implementations",
"definition": "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.",
"comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
"alias": [
"extensions",
"user content"
],
"min": 0,
"max": "*",
"base": {
"path": "Element.extension",
"min": 0,
"max": "*"
},
"type": [
{
"code": "Extension"
}
],
"constraint": [
{
"key": "ele-1",
"severity": "error",
"human": "All FHIR elements must have a @value or children",
"expression": "hasValue() or (children().count() > id.count())",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element"
},
{
"key": "ext-1",
"severity": "error",
"human": "Must have either extensions or value[x], not both",
"expression": "extension.exists() != value.exists()",
"xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
"source": "http://hl7.org/fhir/StructureDefinition/Extension"
}
],
"isModifier": false,
"isSummary": false,
"mapping": [
{
"identity": "rim",
"map": "n/a"
}
]
},
{
"id": "Extension.extension:matchedAntigen",
"path": "Extension.extension",
"sliceName": "matchedAntigen",
"short": "Specific antigen confirmed matched/negative",
"definition": "A specific red cell antigen that was confirmed negative (matched) in the selected blood product.",
"min": 0,
"max": "*",
"base": {
"path": "Element.extension",
"min": 0,
"max": "*"
},
"type": [
{
"code": "Extension"
}
],
"constraint": [
{
"key": "ele-1",
"severity": "error",
"human": "All FHIR elements must have a @value or children",
"expression": "hasValue() or (children().count() > id.count())",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element"
},
{
"key": "ext-1",
"severity": "error",
"human": "Must have either extensions or value[x], not both",
"expression": "extension.exists() != value.exists()",
"xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
"source": "http://hl7.org/fhir/StructureDefinition/Extension"
}
],
"mustSupport": true,
"isModifier": false,
"isSummary": false
},
{
"id": "Extension.extension:matchedAntigen.id",
"path": "Extension.extension.id",
"representation": [
"xmlAttr"
],
"short": "Unique id for inter-element referencing",
"definition": "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.",
"min": 0,
"max": "1",
"base": {
"path": "Element.id",
"min": 0,
"max": "1"
},
"type": [
{
"extension": [
{
"url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
"valueUrl": "string"
}
],
"code": "http://hl7.org/fhirpath/System.String"
}
],
"isModifier": false,
"isSummary": false,
"mapping": [
{
"identity": "rim",
"map": "n/a"
}
]
},
{
"id": "Extension.extension:matchedAntigen.extension",
"path": "Extension.extension.extension",
"slicing": {
"discriminator": [
{
"type": "value",
"path": "url"
}
],
"description": "Extensions are always sliced by (at least) url",
"rules": "open"
},
"short": "Extension",
"definition": "An Extension",
"min": 0,
"max": "0",
"base": {
"path": "Element.extension",
"min": 0,
"max": "*"
},
"type": [
{
"code": "Extension"
}
],
"constraint": [
{
"key": "ele-1",
"severity": "error",
"human": "All FHIR elements must have a @value or children",
"expression": "hasValue() or (children().count() > id.count())",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element"
},
{
"key": "ext-1",
"severity": "error",
"human": "Must have either extensions or value[x], not both",
"expression": "extension.exists() != value.exists()",
"xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
"source": "http://hl7.org/fhir/StructureDefinition/Extension"
}
],
"isModifier": false,
"isSummary": false
},
{
"id": "Extension.extension:matchedAntigen.url",
"path": "Extension.extension.url",
"representation": [
"xmlAttr"
],
"short": "identifies the meaning of the extension",
"definition": "Source of the definition for the extension code - a logical name or a URL.",
"comment": "The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.",
"min": 1,
"max": "1",
"base": {
"path": "Extension.url",
"min": 1,
"max": "1"
},
"type": [
{
"extension": [
{
"url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
"valueUrl": "uri"
}
],
"code": "http://hl7.org/fhirpath/System.String"
}
],
"fixedUri": "matchedAntigen",
"isModifier": false,
"isSummary": false,
"mapping": [
{
"identity": "rim",
"map": "N/A"
}
]
},
{
"id": "Extension.extension:matchedAntigen.value[x]",
"path": "Extension.extension.value[x]",
"short": "Value of extension",
"definition": "Value of extension - must be one of a constrained set of the data types (see [Extensibility](http://hl7.org/fhir/R4/extensibility.html) for a list).",
"min": 0,
"max": "1",
"base": {
"path": "Extension.value[x]",
"min": 0,
"max": "1"
},
"type": [
{
"code": "CodeableConcept"
}
],
"constraint": [
{
"key": "ele-1",
"severity": "error",
"human": "All FHIR elements must have a @value or children",
"expression": "hasValue() or (children().count() > id.count())",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element"
}
],
"isModifier": false,
"isSummary": false,
"binding": {
"strength": "extensible",
"valueSet": "http://hl7.org/fhir/us/uscdi-scd/ValueSet/scd-red-cell-antigen-vs"
},
"mapping": [
{
"identity": "rim",
"map": "N/A"
}
]
},
{
"id": "Extension.extension:matchingProtocol",
"path": "Extension.extension",
"sliceName": "matchingProtocol",
"short": "Antigen matching protocol used",
"definition": "The institutional or standard matching protocol applied (e.g., 'CcEeK matching', 'Extended 5-antigen match', 'Full phenotype match').",
"min": 0,
"max": "1",
"base": {
"path": "Element.extension",
"min": 0,
"max": "*"
},
"type": [
{
"code": "Extension"
}
],
"constraint": [
{
"key": "ele-1",
"severity": "error",
"human": "All FHIR elements must have a @value or children",
"expression": "hasValue() or (children().count() > id.count())",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element"
},
{
"key": "ext-1",
"severity": "error",
"human": "Must have either extensions or value[x], not both",
"expression": "extension.exists() != value.exists()",
"xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
"source": "http://hl7.org/fhir/StructureDefinition/Extension"
}
],
"mustSupport": true,
"isModifier": false,
"isSummary": false
},
{
"id": "Extension.extension:matchingProtocol.id",
"path": "Extension.extension.id",
"representation": [
"xmlAttr"
],
"short": "Unique id for inter-element referencing",
"definition": "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.",
"min": 0,
"max": "1",
"base": {
"path": "Element.id",
"min": 0,
"max": "1"
},
"type": [
{
"extension": [
{
"url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
"valueUrl": "string"
}
],
"code": "http://hl7.org/fhirpath/System.String"
}
],
"isModifier": false,
"isSummary": false,
"mapping": [
{
"identity": "rim",
"map": "n/a"
}
]
},
{
"id": "Extension.extension:matchingProtocol.extension",
"path": "Extension.extension.extension",
"slicing": {
"discriminator": [
{
"type": "value",
"path": "url"
}
],
"description": "Extensions are always sliced by (at least) url",
"rules": "open"
},
"short": "Extension",
"definition": "An Extension",
"min": 0,
"max": "0",
"base": {
"path": "Element.extension",
"min": 0,
"max": "*"
},
"type": [
{
"code": "Extension"
}
],
"constraint": [
{
"key": "ele-1",
"severity": "error",
"human": "All FHIR elements must have a @value or children",
"expression": "hasValue() or (children().count() > id.count())",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element"
},
{
"key": "ext-1",
"severity": "error",
"human": "Must have either extensions or value[x], not both",
"expression": "extension.exists() != value.exists()",
"xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
"source": "http://hl7.org/fhir/StructureDefinition/Extension"
}
],
"isModifier": false,
"isSummary": false
},
{
"id": "Extension.extension:matchingProtocol.url",
"path": "Extension.extension.url",
"representation": [
"xmlAttr"
],
"short": "identifies the meaning of the extension",
"definition": "Source of the definition for the extension code - a logical name or a URL.",
"comment": "The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.",
"min": 1,
"max": "1",
"base": {
"path": "Extension.url",
"min": 1,
"max": "1"
},
"type": [
{
"extension": [
{
"url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
"valueUrl": "uri"
}
],
"code": "http://hl7.org/fhirpath/System.String"
}
],
"fixedUri": "matchingProtocol",
"isModifier": false,
"isSummary": false,
"mapping": [
{
"identity": "rim",
"map": "N/A"
}
]
},
{
"id": "Extension.extension:matchingProtocol.value[x]",
"path": "Extension.extension.value[x]",
"short": "Value of extension",
"definition": "Value of extension - must be one of a constrained set of the data types (see [Extensibility](http://hl7.org/fhir/R4/extensibility.html) for a list).",
"min": 0,
"max": "1",
"base": {
"path": "Extension.value[x]",
"min": 0,
"max": "1"
},
"type": [
{
"code": "string"
}
],
"constraint": [
{
"key": "ele-1",
"severity": "error",
"human": "All FHIR elements must have a @value or children",
"expression": "hasValue() or (children().count() > id.count())",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element"
}
],
"isModifier": false,
"isSummary": false,
"mapping": [
{
"identity": "rim",
"map": "N/A"
}
]
},
{
"id": "Extension.url",
"path": "Extension.url",
"representation": [
"xmlAttr"
],
"short": "identifies the meaning of the extension",
"definition": "Source of the definition for the extension code - a logical name or a URL.",
"comment": "The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.",
"min": 1,
"max": "1",
"base": {
"path": "Extension.url",
"min": 1,
"max": "1"
},
"type": [
{
"extension": [
{
"url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
"valueUrl": "uri"
}
],
"code": "http://hl7.org/fhirpath/System.String"
}
],
"fixedUri": "http://hl7.org/fhir/us/uscdi-scd/StructureDefinition/scd-transfusion-antigen-match",
"isModifier": false,
"isSummary": false,
"mapping": [
{
"identity": "rim",
"map": "N/A"
}
]
},
{
"id": "Extension.value[x]",
"path": "Extension.value[x]",
"short": "Value of extension",
"definition": "Value of extension - must be one of a constrained set of the data types (see [Extensibility](http://hl7.org/fhir/R4/extensibility.html) for a list).",
"min": 0,
"max": "0",
"base": {
"path": "Extension.value[x]",
"min": 0,
"max": "1"
},
"type": [
{
"code": "base64Binary"
},
{
"code": "boolean"
},
{
"code": "canonical"
},
{
"code": "code"
},
{
"code": "date"
},
{
"code": "dateTime"
},
{
"code": "decimal"
},
{
"code": "id"
},
{
"code": "instant"
},
{
"code": "integer"
},
{
"code": "markdown"
},
{
"code": "oid"
},
{
"code": "positiveInt"
},
{
"code": "string"
},
{
"code": "time"
},
{
"code": "unsignedInt"
},
{
"code": "uri"
},
{
"code": "url"
},
{
"code": "uuid"
},
{
"code": "Address"
},
{
"code": "Age"
},
{
"code": "Annotation"
},
{
"code": "Attachment"
},
{
"code": "CodeableConcept"
},
{
"code": "Coding"
},
{
"code": "ContactPoint"
},
{
"code": "Count"
},
{
"code": "Distance"
},
{
"code": "Duration"
},
{
"code": "HumanName"
},
{
"code": "Identifier"
},
{
"code": "Money"
},
{
"code": "Period"
},
{
"code": "Quantity"
},
{
"code": "Range"
},
{
"code": "Ratio"
},
{
"code": "Reference"
},
{
"code": "SampledData"
},
{
"code": "Signature"
},
{
"code": "Timing"
},
{
"code": "ContactDetail"
},
{
"code": "Contributor"
},
{
"code": "DataRequirement"
},
{
"code": "Expression"
},
{
"code": "ParameterDefinition"
},
{
"code": "RelatedArtifact"
},
{
"code": "TriggerDefinition"
},
{
"code": "UsageContext"
},
{
"code": "Dosage"
},
{
"code": "Meta"
}
],
"constraint": [
{
"key": "ele-1",
"severity": "error",
"human": "All FHIR elements must have a @value or children",
"expression": "hasValue() or (children().count() > id.count())",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element"
}
],
"isModifier": false,
"isSummary": false,
"mapping": [
{
"identity": "rim",
"map": "N/A"
}
]
}
]
},
"differential": {
"element": [
{
"id": "Extension",
"path": "Extension"
},
{
"id": "Extension.extension:matchedAntigen",
"path": "Extension.extension",
"sliceName": "matchedAntigen",
"short": "Specific antigen confirmed matched/negative",
"definition": "A specific red cell antigen that was confirmed negative (matched) in the selected blood product.",
"min": 0,
"max": "*",
"mustSupport": true
},
{
"id": "Extension.extension:matchedAntigen.extension",
"path": "Extension.extension.extension",
"max": "0"
},
{
"id": "Extension.extension:matchedAntigen.url",
"path": "Extension.extension.url",
"fixedUri": "matchedAntigen"
},
{
"id": "Extension.extension:matchedAntigen.value[x]",
"path": "Extension.extension.value[x]",
"type": [
{
"code": "CodeableConcept"
}
],
"binding": {
"strength": "extensible",
"valueSet": "http://hl7.org/fhir/us/uscdi-scd/ValueSet/scd-red-cell-antigen-vs"
}
},
{
"id": "Extension.extension:matchingProtocol",
"path": "Extension.extension",
"sliceName": "matchingProtocol",
"short": "Antigen matching protocol used",
"definition": "The institutional or standard matching protocol applied (e.g., 'CcEeK matching', 'Extended 5-antigen match', 'Full phenotype match').",
"min": 0,
"max": "1",
"mustSupport": true
},
{
"id": "Extension.extension:matchingProtocol.extension",
"path": "Extension.extension.extension",
"max": "0"
},
{
"id": "Extension.extension:matchingProtocol.url",
"path": "Extension.extension.url",
"fixedUri": "matchingProtocol"
},
{
"id": "Extension.extension:matchingProtocol.value[x]",
"path": "Extension.extension.value[x]",
"type": [
{
"code": "string"
}
]
},
{
"id": "Extension.url",
"path": "Extension.url",
"fixedUri": "http://hl7.org/fhir/us/uscdi-scd/StructureDefinition/scd-transfusion-antigen-match"
},
{
"id": "Extension.value[x]",
"path": "Extension.value[x]",
"max": "0"
}
]
}
}