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FHIR IG analytics

Packagefhir.nwgenomics.nhs.uk
Resource TypeBundle
Idvalidation-oo.json
FHIR VersionR4

Resources that use this resource

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Narrative

No narrative content found in resource


Source1

{
  "resourceType": "Bundle",
  "type": "collection",
  "timestamp": "2026-02-10T04:32:14.572+00:00",
  "entry": [
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/ImplementationGuide-fhir.nwgenomics.nhs.uk",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ImplementationGuide-fhir.nwgenomics.nhs.uk",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8944
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              }
            ],
            "severity": "error",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'http://hl7.org/fhir/tools/StructureDefinition/expansion-parameters'"
            },
            "expression": [
              "ImplementationGuide/fhir.nwgenomics.nhs.uk: ImplementationGuide.definition.extension[36].url"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 17392
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_String_WS"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "value should not start or finish with whitespace '\\n`NHS Data Model and Dictionary` [ADMISSION SOURCE](https://www.datadictionary.nhs.uk/attributes/admission_source.html)\\n- [UKCoreSourceOfAdmission](https://simplifier.net/hl7fhirukcorer4/valueset-ukcore-sourceofadmission)'"
            },
            "expression": [
              "ImplementationGuide/fhir.nwgenomics.nhs.uk: ImplementationGuide.definition.resource[3].description"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 30474
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_String_WS"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "value should not start or finish with whitespace '\\nThis is for background information around the specimen collection process, it is not considered part of this genomic specification.'"
            },
            "expression": [
              "ImplementationGuide/fhir.nwgenomics.nhs.uk: ImplementationGuide.definition.resource[37].description"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 51319
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_String_WS"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "value should not start or finish with whitespace '\\nThis is for background information for genomic test ordering.'"
            },
            "expression": [
              "ImplementationGuide/fhir.nwgenomics.nhs.uk: ImplementationGuide.definition.resource[90].description"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 51971
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_String_WS"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "value should not start or finish with whitespace '\\nThis is for background information for genomic test reporting.'"
            },
            "expression": [
              "ImplementationGuide/fhir.nwgenomics.nhs.uk: ImplementationGuide.definition.resource[92].description"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 2157
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "IG_DEPENDENCY_DIRECT"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The URL should refer directly to the ImplementationGuide resource (e.g. include '/ImplementationGuide/')"
            },
            "expression": [
              "ImplementationGuide/fhir.nwgenomics.nhs.uk: ImplementationGuide.dependsOn[2]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 2157
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "IG_DEPENDENCY_INVALID_URL"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The canonical URL https://simplifier.net/guide/ukcoreversionhistory doesn't point to an actual ImplementationGuide resource"
            },
            "expression": [
              "ImplementationGuide/fhir.nwgenomics.nhs.uk: ImplementationGuide.dependsOn[2]"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/ActorDefinition-AutomationManager",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ActorDefinition-AutomationManager"
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/ActorDefinition-ClinicalDocument",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ActorDefinition-ClinicalDocument"
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/ActorDefinition-Intermediary",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ActorDefinition-Intermediary"
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/ActorDefinition-OrderFiller",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ActorDefinition-OrderFiller"
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/ActorDefinition-OrderPlacer",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ActorDefinition-OrderPlacer"
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/ActorDefinition-OrderResultTracker",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ActorDefinition-OrderResultTracker",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1070
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ActorDefinition#cnl-0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: cnl-0: 'Name should be usable as an identifier for the module by machine processing applications such as code generation (name.exists() implies name.matches('^[A-Z]([A-Za-z0-9_]){1,254}[%content%]#x27;))' (defined in http://hl7.org/fhir/StructureDefinition/ActorDefinition)"
            },
            "expression": [
              "ActorDefinition/OrderResultTracker: ActorDefinition"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/ActorDefinition-PatientIdentitySource",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ActorDefinition-PatientIdentitySource"
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/ActorDefinition-ProviderInformationSource",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ActorDefinition-ProviderInformationSource"
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/Binary-0a898233-763c-405d-8172-8c4f07e6e636",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Binary-0a898233-763c-405d-8172-8c4f07e6e636"
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/Binary-d6eeedd1-92d3-45b9-bf33-6401e804425f",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Binary-d6eeedd1-92d3-45b9-bf33-6401e804425f"
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/Bundle-036ceda5-8eea-42d5-9e8f-f977287c0dd6",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Bundle-036ceda5-8eea-42d5-9e8f-f977287c0dd6",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 9
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 82
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://example.nhs.uk/FHIR/R4/Condition?patient=Patient-Liverpool'"
            },
            "expression": [
              "Bundle/036ceda5-8eea-42d5-9e8f-f977287c0dd6: Bundle.link[0].url"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 28
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Coding_has_no_system__cannot_validate"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Coding has no system. A code with no system has no defined meaning, and it cannot be validated. A system should be provided"
            },
            "expression": [
              "Bundle/036ceda5-8eea-42d5-9e8f-f977287c0dd6: Bundle.entry[0].resource/*Condition/c8f82825-e4cb-4e1f-b728-3fd2808e93db*/.clinicalStatus.coding[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 28
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Terminology_TX_NoValid_1_CC"
              }
            ],
            "severity": "error",
            "code": "code-invalid",
            "details": {
              "text": "None of the codings provided are in the value set 'Condition Clinical Status Codes' (http://hl7.org/fhir/ValueSet/condition-clinical|4.0.1), and a coding from this value set is required) (codes = null#final)"
            },
            "expression": [
              "Bundle/036ceda5-8eea-42d5-9e8f-f977287c0dd6: Bundle.entry[0].resource/*Condition/c8f82825-e4cb-4e1f-b728-3fd2808e93db*/.clinicalStatus"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 35
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Coding_has_no_system__cannot_validate"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Coding has no system. A code with no system has no defined meaning, and it cannot be validated. A system should be provided"
            },
            "expression": [
              "Bundle/036ceda5-8eea-42d5-9e8f-f977287c0dd6: Bundle.entry[0].resource/*Condition/c8f82825-e4cb-4e1f-b728-3fd2808e93db*/.verificationStatus.coding[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 35
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Terminology_TX_NoValid_1_CC"
              }
            ],
            "severity": "error",
            "code": "code-invalid",
            "details": {
              "text": "None of the codings provided are in the value set 'ConditionVerificationStatus' (http://hl7.org/fhir/ValueSet/condition-ver-status|4.0.1), and a coding from this value set is required) (codes = null#confirmed)"
            },
            "expression": [
              "Bundle/036ceda5-8eea-42d5-9e8f-f977287c0dd6: Bundle.entry[0].resource/*Condition/c8f82825-e4cb-4e1f-b728-3fd2808e93db*/.verificationStatus"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 54
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              }
            ],
            "severity": "error",
            "code": "exception",
            "details": {
              "text": "Error from https://tx.fhir.org/r4: The filter \"constraint = descendantOf 404684003 OR descendantOf 413350009 OR descendantOf 272379006\" from the value set https://fhir.hl7.org.uk/ValueSet/UKCore-ConditionCode was not understood in the context of http://snomed.info/sct (1)"
            },
            "expression": [
              "Bundle/036ceda5-8eea-42d5-9e8f-f977287c0dd6: Bundle.entry[0].resource/*Condition/c8f82825-e4cb-4e1f-b728-3fd2808e93db*/.code"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/Bundle-187a20ef-9b81-4c83-84f7-140c210f8706",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Bundle-187a20ef-9b81-4c83-84f7-140c210f8706",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 9
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 114
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://example.nhs.uk/FHIR/R4/Observation?code=http://loinc.org|69548-6&patient=Patient-Liverpool'"
            },
            "expression": [
              "Bundle/187a20ef-9b81-4c83-84f7-140c210f8706: Bundle.link[0].url"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 67
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Unknown_Code_in_Version"
              }
            ],
            "severity": "error",
            "code": "code-invalid",
            "details": {
              "text": "Unknown code 'LA26398' in the CodeSystem 'http://loinc.org' version '2.81'"
            },
            "expression": [
              "Bundle/187a20ef-9b81-4c83-84f7-140c210f8706: Bundle.entry[0].resource/*Observation/8385c2fd-313d-4fd5-b98e-d5ea4bae6f99*/.method.coding[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 87
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 14
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "Unable to check whether the code is in the value set '' because the code system http://www.genenames.org was not found"
            },
            "expression": [
              "Bundle/187a20ef-9b81-4c83-84f7-140c210f8706: Bundle.entry[0].resource/*Observation/8385c2fd-313d-4fd5-b98e-d5ea4bae6f99*/.component[0].value.ofType(CodeableConcept)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 87
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 14
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"
            },
            "expression": [
              "Bundle/187a20ef-9b81-4c83-84f7-140c210f8706: Bundle.entry[0].resource/*Observation/8385c2fd-313d-4fd5-b98e-d5ea4bae6f99*/.component[0].value.ofType(CodeableConcept).coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 107
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 14
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"
            },
            "expression": [
              "Bundle/187a20ef-9b81-4c83-84f7-140c210f8706: Bundle.entry[0].resource/*Observation/8385c2fd-313d-4fd5-b98e-d5ea4bae6f99*/.component[1].value.ofType(CodeableConcept)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 107
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 14
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"
            },
            "expression": [
              "Bundle/187a20ef-9b81-4c83-84f7-140c210f8706: Bundle.entry[0].resource/*Observation/8385c2fd-313d-4fd5-b98e-d5ea4bae6f99*/.component[1].value.ofType(CodeableConcept).coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 126
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 14
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Unknown_Code_in_Version"
              }
            ],
            "severity": "error",
            "code": "code-invalid",
            "details": {
              "text": "Unknown code 'NC_000003.11' in the CodeSystem 'http://varnomen.hgvs.org' version '2.0'"
            },
            "expression": [
              "Bundle/187a20ef-9b81-4c83-84f7-140c210f8706: Bundle.entry[0].resource/*Observation/8385c2fd-313d-4fd5-b98e-d5ea4bae6f99*/.component[2].value.ofType(CodeableConcept).coding[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 145
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 14
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"
            },
            "expression": [
              "Bundle/187a20ef-9b81-4c83-84f7-140c210f8706: Bundle.entry[0].resource/*Observation/8385c2fd-313d-4fd5-b98e-d5ea4bae6f99*/.component[3].value.ofType(CodeableConcept)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 145
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 14
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"
            },
            "expression": [
              "Bundle/187a20ef-9b81-4c83-84f7-140c210f8706: Bundle.entry[0].resource/*Observation/8385c2fd-313d-4fd5-b98e-d5ea4bae6f99*/.component[3].value.ofType(CodeableConcept).coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 215
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 14
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Display_Name_for__should_be_one_of__instead_of"
              }
            ],
            "severity": "error",
            "code": "invalid",
            "details": {
              "text": "Wrong Display Name 'Genomic ref allele' for http://loinc.org#69547-8. Valid display is one of 4 choices: 'Genomic ref allele [ID]' (en-US), 'Genomic ref allele [ID]' (en-US), 'Ref nucleotide' (en-US) or 'Reference nucleotide, Blood or tissue specimen' (en-US) (for the language(s) 'en-GB')"
            },
            "expression": [
              "Bundle/187a20ef-9b81-4c83-84f7-140c210f8706: Bundle.entry[0].resource/*Observation/8385c2fd-313d-4fd5-b98e-d5ea4bae6f99*/.component[7].code.coding[0].display"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 126
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 14
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Terminology_TX_NoValid_1_CC"
              }
            ],
            "severity": "error",
            "code": "code-invalid",
            "details": {
              "text": "None of the codings provided are in the value set 'Human Genome Variation Society (HGVS) Nomenclature' (http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs|3.0.0), and a coding from this value set is required) (codes = http://varnomen.hgvs.org#NC_000003.11)"
            },
            "expression": [
              "Bundle/187a20ef-9b81-4c83-84f7-140c210f8706: Bundle.entry[0].resource/*Observation/8385c2fd-313d-4fd5-b98e-d5ea4bae6f99*/.component[2].value.ofType(CodeableConcept)"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/Bundle-41a20f74-643f-4073-968a-ee003160734f",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Bundle-41a20f74-643f-4073-968a-ee003160734f",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 9
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 125
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://example.nhs.uk/FHIR/R4/Observation?combo-code=http://loinc.org|48018-6&combo-code-value-concept=NTHL1'"
            },
            "expression": [
              "Bundle/41a20f74-643f-4073-968a-ee003160734f: Bundle.link[0].url"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 67
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Unknown_Code_in_Version"
              }
            ],
            "severity": "error",
            "code": "code-invalid",
            "details": {
              "text": "Unknown code 'LA26398' in the CodeSystem 'http://loinc.org' version '2.81'"
            },
            "expression": [
              "Bundle/41a20f74-643f-4073-968a-ee003160734f: Bundle.entry[0].resource/*Observation/8385c2fd-313d-4fd5-b98e-d5ea4bae6f99*/.method.coding[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 87
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 14
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "Unable to check whether the code is in the value set '' because the code system http://www.genenames.org was not found"
            },
            "expression": [
              "Bundle/41a20f74-643f-4073-968a-ee003160734f: Bundle.entry[0].resource/*Observation/8385c2fd-313d-4fd5-b98e-d5ea4bae6f99*/.component[0].value.ofType(CodeableConcept)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 87
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 14
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"
            },
            "expression": [
              "Bundle/41a20f74-643f-4073-968a-ee003160734f: Bundle.entry[0].resource/*Observation/8385c2fd-313d-4fd5-b98e-d5ea4bae6f99*/.component[0].value.ofType(CodeableConcept).coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 107
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 14
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"
            },
            "expression": [
              "Bundle/41a20f74-643f-4073-968a-ee003160734f: Bundle.entry[0].resource/*Observation/8385c2fd-313d-4fd5-b98e-d5ea4bae6f99*/.component[1].value.ofType(CodeableConcept)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 107
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 14
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"
            },
            "expression": [
              "Bundle/41a20f74-643f-4073-968a-ee003160734f: Bundle.entry[0].resource/*Observation/8385c2fd-313d-4fd5-b98e-d5ea4bae6f99*/.component[1].value.ofType(CodeableConcept).coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 126
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 14
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Unknown_Code_in_Version"
              }
            ],
            "severity": "error",
            "code": "code-invalid",
            "details": {
              "text": "Unknown code 'NC_000003.11' in the CodeSystem 'http://varnomen.hgvs.org' version '2.0'"
            },
            "expression": [
              "Bundle/41a20f74-643f-4073-968a-ee003160734f: Bundle.entry[0].resource/*Observation/8385c2fd-313d-4fd5-b98e-d5ea4bae6f99*/.component[2].value.ofType(CodeableConcept).coding[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 145
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 14
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"
            },
            "expression": [
              "Bundle/41a20f74-643f-4073-968a-ee003160734f: Bundle.entry[0].resource/*Observation/8385c2fd-313d-4fd5-b98e-d5ea4bae6f99*/.component[3].value.ofType(CodeableConcept)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 145
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 14
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"
            },
            "expression": [
              "Bundle/41a20f74-643f-4073-968a-ee003160734f: Bundle.entry[0].resource/*Observation/8385c2fd-313d-4fd5-b98e-d5ea4bae6f99*/.component[3].value.ofType(CodeableConcept).coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 215
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 14
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Display_Name_for__should_be_one_of__instead_of"
              }
            ],
            "severity": "error",
            "code": "invalid",
            "details": {
              "text": "Wrong Display Name 'Genomic ref allele' for http://loinc.org#69547-8. Valid display is one of 4 choices: 'Genomic ref allele [ID]' (en-US), 'Genomic ref allele [ID]' (en-US), 'Ref nucleotide' (en-US) or 'Reference nucleotide, Blood or tissue specimen' (en-US) (for the language(s) 'en-GB')"
            },
            "expression": [
              "Bundle/41a20f74-643f-4073-968a-ee003160734f: Bundle.entry[0].resource/*Observation/8385c2fd-313d-4fd5-b98e-d5ea4bae6f99*/.component[7].code.coding[0].display"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 126
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 14
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Terminology_TX_NoValid_1_CC"
              }
            ],
            "severity": "error",
            "code": "code-invalid",
            "details": {
              "text": "None of the codings provided are in the value set 'Human Genome Variation Society (HGVS) Nomenclature' (http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs|3.0.0), and a coding from this value set is required) (codes = http://varnomen.hgvs.org#NC_000003.11)"
            },
            "expression": [
              "Bundle/41a20f74-643f-4073-968a-ee003160734f: Bundle.entry[0].resource/*Observation/8385c2fd-313d-4fd5-b98e-d5ea4bae6f99*/.component[2].value.ofType(CodeableConcept)"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/Bundle-92a0a6c6-404f-4347-8de4-fa1c457a037e",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Bundle-92a0a6c6-404f-4347-8de4-fa1c457a037e",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 9
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 112
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://example.nhs.uk/FHIR/R4/Observation?code=diagnostic-implication&patient=Patient-Liverpool'"
            },
            "expression": [
              "Bundle/92a0a6c6-404f-4347-8de4-fa1c457a037e: Bundle.link[0].url"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 102
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 14
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "UNKNOWN_CODE_IN_FRAGMENT"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "Unknown Code 'R210' in the CodeSystem 'https://fhir.nwgenomics.nhs.uk/CodeSystem/GenomicClinicalIndication' version '0.1.0' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"
            },
            "expression": [
              "Bundle/92a0a6c6-404f-4347-8de4-fa1c457a037e: Bundle.entry[0].resource/*Observation/6beb613f-d303-42af-b025-86e8e0872061*/.component[1].value.ofType(CodeableConcept).coding[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 102
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 14
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Unknown_Code_in_Version"
              }
            ],
            "severity": "error",
            "code": "code-invalid",
            "details": {
              "text": "Unknown code '1365861003' in the CodeSystem 'http://snomed.info/sct' version 'http://snomed.info/sct/83821000000107/version/20230412' (UK Edition)"
            },
            "expression": [
              "Bundle/92a0a6c6-404f-4347-8de4-fa1c457a037e: Bundle.entry[0].resource/*Observation/6beb613f-d303-42af-b025-86e8e0872061*/.component[1].value.ofType(CodeableConcept).coding[1].code"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/Bundle-FHIRDocumentGeneticReportBundle",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Bundle-FHIRDocumentGeneticReportBundle",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 6
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 47
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'urn:oid:2.16.724.4.8.10.200.10'"
            },
            "expression": [
              "Bundle/FHIRDocumentGeneticReportBundle: Bundle.identifier.system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 135
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 72
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'urn:oid:1.2.840.114350.1.13.611.3.7.5.737384.14'"
            },
            "expression": [
              "Bundle/FHIRDocumentGeneticReportBundle: Bundle.entry[1].resource/*Patient/Patient-OctaviaCHISLETT-9449305552*/.identifier[2].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 454
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 43
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_Base64_Valid"
              }
            ],
            "severity": "error",
            "code": "invalid",
            "details": {
              "text": "The value 'ig-loader-R24-0WH7-1.pdf' is not a valid Base64 value"
            },
            "expression": [
              "Bundle/FHIRDocumentGeneticReportBundle: Bundle.entry[4].resource/*Binary/d6eeedd1-92d3-45b9-bf33-6401e804425f*/.data"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 457
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 6
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Bundle_BUNDLE_Entry_Orphan_DOCUMENT"
              }
            ],
            "severity": "error",
            "code": "informational",
            "details": {
              "text": "Entry 'urn:uuid:ee9b8fcc-c233-43e1-b7fb-b58ce4cf1db8' isn't reachable by traversing links (forward or backward) from the Composition"
            },
            "expression": [
              "Bundle/FHIRDocumentGeneticReportBundle: Bundle.entry[6]"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/Bundle-GenomicsOrderMessageAttachment",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Bundle-GenomicsOrderMessageAttachment",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 115
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 72
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'urn:oid:1.2.840.114350.1.13.611.3.7.5.737384.14'"
            },
            "expression": [
              "Bundle/GenomicsOrderMessageAttachment: Bundle.entry[1].resource/*Patient/Patient-OctaviaCHISLETT-9449305552*/.identifier[2].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 226
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TERMINOLOGY_TX_SYSTEM_NO_CODE"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "A code with no system has no defined meaning, and it cannot be validated. A system should be provided"
            },
            "expression": [
              "Bundle/GenomicsOrderMessageAttachment: Bundle.entry[2].resource/*Encounter/984b8a89-4194-4eb4-a7ea-ca8049ebeea3*/.class"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 313
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 67
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'urn:oid:1.2.840.114350.1.13.0.1.7.2.798268'"
            },
            "expression": [
              "Bundle/GenomicsOrderMessageAttachment: Bundle.entry[4].resource/*ServiceRequest/ServiceRequestGenomicsOrderAttachment*/.identifier[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 297
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 12
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "SLICING_CANNOT_BE_EVALUATED"
              }
            ],
            "severity": "error",
            "code": "processing",
            "details": {
              "text": "Slicing cannot be evaluated: Could not match discriminator (type) for slice ServiceRequest.identifier:OrderFillerNumber in profile https://fhir.nwgenomics.nhs.uk/StructureDefinition/ServiceRequest|0.1.0 - the discriminator [type] does not have fixed value, binding or existence assertions"
            },
            "expression": [
              "Bundle/GenomicsOrderMessageAttachment: Bundle.entry[4].resource/*ServiceRequest/ServiceRequestGenomicsOrderAttachment*/.identifier[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 315
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 12
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "SLICING_CANNOT_BE_EVALUATED"
              }
            ],
            "severity": "error",
            "code": "processing",
            "details": {
              "text": "Slicing cannot be evaluated: Could not match discriminator (type) for slice ServiceRequest.identifier:OrderFillerNumber in profile https://fhir.nwgenomics.nhs.uk/StructureDefinition/ServiceRequest|0.1.0 - the discriminator [type] does not have fixed value, binding or existence assertions"
            },
            "expression": [
              "Bundle/GenomicsOrderMessageAttachment: Bundle.entry[4].resource/*ServiceRequest/ServiceRequestGenomicsOrderAttachment*/.identifier[1]"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/Bundle-GenomicsOrderMessageCodedEntries",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Bundle-GenomicsOrderMessageCodedEntries",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 115
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 72
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'urn:oid:1.2.840.114350.1.13.611.3.7.5.737384.14'"
            },
            "expression": [
              "Bundle/GenomicsOrderMessageCodedEntries: Bundle.entry[1].resource/*Patient/Patient-OctaviaCHISLETT-9449305552*/.identifier[2].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 226
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TERMINOLOGY_TX_SYSTEM_NO_CODE"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "A code with no system has no defined meaning, and it cannot be validated. A system should be provided"
            },
            "expression": [
              "Bundle/GenomicsOrderMessageCodedEntries: Bundle.entry[2].resource/*Encounter/984b8a89-4194-4eb4-a7ea-ca8049ebeea3*/.class"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 313
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 67
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'urn:oid:1.2.840.114350.1.13.0.1.7.2.798268'"
            },
            "expression": [
              "Bundle/GenomicsOrderMessageCodedEntries: Bundle.entry[4].resource/*ServiceRequest/ServiceRequestGenomicsOrderCodedEntries*/.identifier[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 297
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 12
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "SLICING_CANNOT_BE_EVALUATED"
              }
            ],
            "severity": "error",
            "code": "processing",
            "details": {
              "text": "Slicing cannot be evaluated: Could not match discriminator (type) for slice ServiceRequest.identifier:OrderFillerNumber in profile https://fhir.nwgenomics.nhs.uk/StructureDefinition/ServiceRequest|0.1.0 - the discriminator [type] does not have fixed value, binding or existence assertions"
            },
            "expression": [
              "Bundle/GenomicsOrderMessageCodedEntries: Bundle.entry[4].resource/*ServiceRequest/ServiceRequestGenomicsOrderCodedEntries*/.identifier[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 315
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 12
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "SLICING_CANNOT_BE_EVALUATED"
              }
            ],
            "severity": "error",
            "code": "processing",
            "details": {
              "text": "Slicing cannot be evaluated: Could not match discriminator (type) for slice ServiceRequest.identifier:OrderFillerNumber in profile https://fhir.nwgenomics.nhs.uk/StructureDefinition/ServiceRequest|0.1.0 - the discriminator [type] does not have fixed value, binding or existence assertions"
            },
            "expression": [
              "Bundle/GenomicsOrderMessageCodedEntries: Bundle.entry[4].resource/*ServiceRequest/ServiceRequestGenomicsOrderCodedEntries*/.identifier[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 430
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "UNKNOWN_CODE_IN_FRAGMENT"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "Unknown Code 'GENEAP' in the CodeSystem 'https://fhir.nwgenomics.nhs.uk/CodeSystem/MFTQuestionIds' version '0.1.0' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"
            },
            "expression": [
              "Bundle/GenomicsOrderMessageCodedEntries: Bundle.entry[5].resource/*Observation/EPIC-OBR-1*/.code.coding[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 520
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "UNKNOWN_CODE_IN_FRAGMENT"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "Unknown Code '230056' in the CodeSystem 'https://fhir.nwgenomics.nhs.uk/CodeSystem/MFTQuestionIds' version '0.1.0' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"
            },
            "expression": [
              "Bundle/GenomicsOrderMessageCodedEntries: Bundle.entry[6].resource/*Observation/OBX-GenomicReferralCategory*/.code.coding[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 572
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              }
            ],
            "severity": "error",
            "code": "exception",
            "details": {
              "text": "Error from https://tx.fhir.org/r4: The filter \"constraint = descendantOf 404684003 OR descendantOf 413350009 OR descendantOf 272379006\" from the value set https://fhir.hl7.org.uk/ValueSet/UKCore-ConditionCode was not understood in the context of http://snomed.info/sct (1)"
            },
            "expression": [
              "Bundle/GenomicsOrderMessageCodedEntries: Bundle.entry[7].resource/*Condition/EPIC-OBX-2*/.code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 621
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "UNKNOWN_CODESYSTEM"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'http://snomed.info/sct' could not be found, so the code cannot be validated"
            },
            "expression": [
              "Bundle/GenomicsOrderMessageCodedEntries: Bundle.entry[8].resource/*Observation/OBX-HighInfectionRiskSample*/.code.coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 684
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "UNKNOWN_CODE_IN_FRAGMENT"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "Unknown Code '230016' in the CodeSystem 'https://fhir.nwgenomics.nhs.uk/CodeSystem/MFTQuestionIds' version '0.1.0' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"
            },
            "expression": [
              "Bundle/GenomicsOrderMessageCodedEntries: Bundle.entry[9].resource/*Observation/EPIC-OBX-4*/.code.coding[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 739
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "UNKNOWN_CODESYSTEM"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'http://snomed.info/sct' could not be found, so the code cannot be validated"
            },
            "expression": [
              "Bundle/GenomicsOrderMessageCodedEntries: Bundle.entry[10].resource/*Observation/OBX-Pregnancy*/.code.coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 802
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "UNKNOWN_CODE_IN_FRAGMENT"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "Unknown Code '231284' in the CodeSystem 'https://fhir.nwgenomics.nhs.uk/CodeSystem/MFTQuestionIds' version '0.1.0' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"
            },
            "expression": [
              "Bundle/GenomicsOrderMessageCodedEntries: Bundle.entry[11].resource/*Observation/EPIC-OBX-6*/.code.coding[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 857
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "UNKNOWN_CODE_IN_FRAGMENT"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "Unknown Code '231285' in the CodeSystem 'https://fhir.nwgenomics.nhs.uk/CodeSystem/MFTQuestionIds' version '0.1.0' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"
            },
            "expression": [
              "Bundle/GenomicsOrderMessageCodedEntries: Bundle.entry[12].resource/*Observation/EPIC-OBX-7*/.code.coding[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 912
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "UNKNOWN_CODE_IN_FRAGMENT"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "Unknown Code '230027' in the CodeSystem 'https://fhir.nwgenomics.nhs.uk/CodeSystem/MFTQuestionIds' version '0.1.0' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"
            },
            "expression": [
              "Bundle/GenomicsOrderMessageCodedEntries: Bundle.entry[13].resource/*Observation/EPIC-OBX-8*/.code.coding[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 967
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "UNKNOWN_CODESYSTEM"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'http://snomed.info/sct' could not be found, so the code cannot be validated"
            },
            "expression": [
              "Bundle/GenomicsOrderMessageCodedEntries: Bundle.entry[14].resource/*Observation/OBX-InformedConsent*/.code.coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1031
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "UNKNOWN_CODE_IN_FRAGMENT"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "Unknown Code '230037' in the CodeSystem 'https://fhir.nwgenomics.nhs.uk/CodeSystem/MFTQuestionIds' version '0.1.0' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"
            },
            "expression": [
              "Bundle/GenomicsOrderMessageCodedEntries: Bundle.entry[15].resource/*Observation/EPIC-OBX-10*/.code.coding[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1086
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "UNKNOWN_CODE_IN_FRAGMENT"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "Unknown Code '230039' in the CodeSystem 'https://fhir.nwgenomics.nhs.uk/CodeSystem/MFTQuestionIds' version '0.1.0' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"
            },
            "expression": [
              "Bundle/GenomicsOrderMessageCodedEntries: Bundle.entry[16].resource/*Observation/EPIC-OBX-11*/.code.coding[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1141
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "UNKNOWN_CODE_IN_FRAGMENT"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "Unknown Code 'unknown' in the CodeSystem 'https://fhir.nwgenomics.nhs.uk/CodeSystem/MFTQuestionIds' version '0.1.0' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"
            },
            "expression": [
              "Bundle/GenomicsOrderMessageCodedEntries: Bundle.entry[17].resource/*Observation/OBX-SupervisingClinician*/.code.coding[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1251
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "UNKNOWN_CODESYSTEM"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'http://snomed.info/sct' could not be found, so the code cannot be validated"
            },
            "expression": [
              "Bundle/GenomicsOrderMessageCodedEntries: Bundle.entry[19].resource/*Observation/OBX-Consanguinity*/.code.coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1314
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "UNKNOWN_CODESYSTEM"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'http://snomed.info/sct' could not be found, so the code cannot be validated"
            },
            "expression": [
              "Bundle/GenomicsOrderMessageCodedEntries: Bundle.entry[20].resource/*Observation/OBX-PregnancyExpectedDeliveryDate*/.code.coding[0].system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/Bundle-GenomicsOrderMessageReplyAcknowledge",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Bundle-GenomicsOrderMessageReplyAcknowledge"
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/Bundle-GenomicsOrderMessageReplyFatal",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Bundle-GenomicsOrderMessageReplyFatal"
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/Bundle-GenomicsOrderMessageReplyOk",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Bundle-GenomicsOrderMessageReplyOk"
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/Bundle-GenomicsOrderSearchSet",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Bundle-GenomicsOrderSearchSet",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 9
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 116
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'http://rie.mft.nhs.uk/Bundle?message.reciever:identifier=R0A&_lastUpdated=>2025-03-01T02:00:02+01:00'"
            },
            "expression": [
              "Bundle/GenomicsOrderSearchSet: Bundle.link[0].url"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 27
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 14
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/DomainResource#dom-6"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: dom-6: 'A resource should have narrative for robust management (text.`div`.exists())' (defined in http://hl7.org/fhir/StructureDefinition/DomainResource) (Best Practice Recommendation)"
            },
            "expression": [
              "Bundle/GenomicsOrderSearchSet: Bundle.entry[0].resource/*Bundle/GenomicsOrderMessageReplyFatal*/.entry[0].resource/*MessageHeader/MessageHeaderGenomicOrderReplyFatal*/"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/Bundle-GenomicsReportMessage",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Bundle-GenomicsReportMessage",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 260
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 72
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'urn:oid:1.2.840.114350.1.13.611.3.7.5.737384.14'"
            },
            "expression": [
              "Bundle/GenomicsReportMessage: Bundle.entry[2].resource/*Patient/Patient-OctaviaCHISLETT-9449305552*/.identifier[2].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 438
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 43
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_Base64_Valid"
              }
            ],
            "severity": "error",
            "code": "invalid",
            "details": {
              "text": "The value 'ig-loader-R24-0WH7-1.pdf' is not a valid Base64 value"
            },
            "expression": [
              "Bundle/GenomicsReportMessage: Bundle.entry[4].resource/*Binary/d6eeedd1-92d3-45b9-bf33-6401e804425f*/.data"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 441
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 6
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Bundle_BUNDLE_Entry_Orphan_MESSAGE"
              }
            ],
            "severity": "warning",
            "code": "informational",
            "details": {
              "text": "Entry 'urn:uuid:ee9b8fcc-c233-43e1-b7fb-b58ce4cf1db8' isn't reachable by traversing links (forward or backward) from the MessageHeader, so its presence should be reviewed (is it needed to process the message?)"
            },
            "expression": [
              "Bundle/GenomicsReportMessage: Bundle.entry[6]"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/Bundle-PDQSearchResults",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Bundle-PDQSearchResults",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 9
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 110
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://example.nhs.uk/FHIR/R4/Patient?identifier=https://fhir.nhs.uk/Id/nhs-number|9449305552'"
            },
            "expression": [
              "Bundle/PDQSearchResults: Bundle.link[0].url"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 71
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 72
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'urn:oid:1.2.840.114350.1.13.611.3.7.5.737384.14'"
            },
            "expression": [
              "Bundle/PDQSearchResults: Bundle.entry[0].resource/*Patient/Patient-OctaviaCHISLETT-9449305552*/.identifier[2].system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/Bundle-PatientMessage",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Bundle-PatientMessage",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 115
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 72
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'urn:oid:1.2.840.114350.1.13.611.3.7.5.737384.14'"
            },
            "expression": [
              "Bundle/PatientMessage: Bundle.entry[1].resource/*Patient/Patient-OctaviaCHISLETT-9449305552*/.identifier[2].system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/Bundle-SDCSearchResults",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Bundle-SDCSearchResults",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 9
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 80
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://example.nhs.uk/FHIR/R4/Questionnaire?id=GenomicTestOrder'"
            },
            "expression": [
              "Bundle/SDCSearchResults: Bundle.link[0].url"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1117
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 28
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Unknown_Code_in_Version"
              }
            ],
            "severity": "error",
            "code": "code-invalid",
            "details": {
              "text": "Unknown code '598151000005105' in the CodeSystem 'http://snomed.info/sct' version 'http://snomed.info/sct/83821000000107/version/20230412' (UK Edition)"
            },
            "expression": [
              "Bundle/SDCSearchResults: Bundle.entry[0].resource/*Questionnaire/GenomicTestOrder*/.item[4].item[2].item[0].item[2].code[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1254
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 12
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/Questionnaire#que-1"
              }
            ],
            "severity": "error",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: que-1: 'Group items must have nested items, display items cannot have nested items ((type='group' implies item.empty().not()) and (type.trace('type')='display' implies item.trace('item').empty()))'"
            },
            "expression": [
              "Bundle/SDCSearchResults: Bundle.entry[0].resource/*Questionnaire/GenomicTestOrder*/.item[5]"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/Bundle-TransactionGenomicsOrderReplyAck",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Bundle-TransactionGenomicsOrderReplyAck",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 21
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 14
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/DomainResource#dom-6"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: dom-6: 'A resource should have narrative for robust management (text.`div`.exists())' (defined in http://hl7.org/fhir/StructureDefinition/DomainResource) (Best Practice Recommendation)"
            },
            "expression": [
              "Bundle/TransactionGenomicsOrderReplyAck: Bundle.entry[0].resource/*Bundle/GenomicsOrderMessageReplyAcknowledge*/.entry[0].resource/*MessageHeader/MessageHeaderGenomicOrderReplyFatalAcknowledge*/"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 7
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 6
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "BUNDLE_ENTRY_URL_ABSOLUTE"
              }
            ],
            "severity": "error",
            "code": "invalid",
            "details": {
              "text": "The fullUrl must be an absolute URL (not 'Bundle/GenomicsOrderMessageReplyAcknowledge')"
            },
            "expression": [
              "Bundle/TransactionGenomicsOrderReplyAck: Bundle.entry[0]"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/Bundle-c39fc97b-e99f-47b2-8660-d3d6b8840d20",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Bundle-c39fc97b-e99f-47b2-8660-d3d6b8840d20",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 9
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 75
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://example.nhs.uk/FHIR/R4/Patient?identifier=A12356565'"
            },
            "expression": [
              "Bundle/c39fc97b-e99f-47b2-8660-d3d6b8840d20: Bundle.link[0].url"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 71
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 72
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'urn:oid:1.2.840.114350.1.13.611.3.7.5.737384.14'"
            },
            "expression": [
              "Bundle/c39fc97b-e99f-47b2-8660-d3d6b8840d20: Bundle.entry[0].resource/*Patient/Patient-OctaviaCHISLETT-9449305552*/.identifier[2].system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/CapabilityStatement-QueryExistingData",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "CapabilityStatement-QueryExistingData",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 7714
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/CapabilityStatement#cpb-15"
              }
            ],
            "severity": "error",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: cpb-15: 'If kind = capability, implementation must be absent, software must be present ((kind != 'capability') or (implementation.exists().not() and software.exists()))'"
            },
            "expression": [
              "CapabilityStatement/QueryExistingData: CapabilityStatement"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/CapabilityStatement-RegionalIntegrationEngine",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "CapabilityStatement-RegionalIntegrationEngine",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 11772
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/CapabilityStatement#cpb-0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: cpb-0: 'Name should be usable as an identifier for the module by machine processing applications such as code generation (name.matches('[A-Z]([A-Za-z0-9_]){0,254}'))'"
            },
            "expression": [
              "CapabilityStatement/RegionalIntegrationEngine: CapabilityStatement"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/CodeSystem-GenomicClinicalIndication",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "CodeSystem-GenomicClinicalIndication"
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/CodeSystem-GenomicTestCode",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "CodeSystem-GenomicTestCode",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "Publisher"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "URL Mismatch https://fhir.nwgenomics.nhs.uk/CodeSystem/GenomicTestCode vs https://fhir.nhs.uk/CodeSystem/England-GenomicTestDirectory"
            },
            "expression": [
              "/scratch/repo/fsh-generated/resources/CodeSystem-GenomicTestCode"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/CodeSystem-GenomicTestOutcomeCode",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "CodeSystem-GenomicTestOutcomeCode"
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/CodeSystem-IGEAP",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "CodeSystem-IGEAP"
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/CodeSystem-MFTQuestionIds",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "CodeSystem-MFTQuestionIds"
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/CodeSystem-NWGMSA",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "CodeSystem-NWGMSA"
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/CodeSystem-NationalHealthIdentifiers",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "CodeSystem-NationalHealthIdentifiers"
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/CodeSystem-ProfessionalLicense",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "CodeSystem-ProfessionalLicense"
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/Composition-Composition-GenomicsReport-OctaviaCHISLETT",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Composition-Composition-GenomicsReport-OctaviaCHISLETT"
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/ConceptMap-LOINCtoSNOMEDUK",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ConceptMap-LOINCtoSNOMEDUK",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 3425
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_SHAREABLE_EXTRA_MISSING"
              }
            ],
            "severity": "warning",
            "code": "required",
            "details": {
              "text": "Published concept maps SHOULD conform to the ShareableConceptMap profile, which says that the element ConceptMap.name should be present, but it is not"
            },
            "expression": [
              "ConceptMap/LOINCtoSNOMEDUK: ConceptMap"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 3425
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_SHAREABLE_MISSING"
              }
            ],
            "severity": "warning",
            "code": "required",
            "details": {
              "text": "Published concept maps SHOULD conform to the ShareableConceptMap profile, which says that the element ConceptMap.experimental is mandatory, but it is not present"
            },
            "expression": [
              "ConceptMap/LOINCtoSNOMEDUK: ConceptMap"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/ConceptMap-SNOMEDLOINCtoSNOMEDUK",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ConceptMap-SNOMEDLOINCtoSNOMEDUK",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 3616
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_SHAREABLE_EXTRA_MISSING"
              }
            ],
            "severity": "warning",
            "code": "required",
            "details": {
              "text": "Published concept maps SHOULD conform to the ShareableConceptMap profile, which says that the element ConceptMap.name should be present, but it is not"
            },
            "expression": [
              "ConceptMap/SNOMEDLOINCtoSNOMEDUK: ConceptMap"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 3616
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_SHAREABLE_MISSING"
              }
            ],
            "severity": "warning",
            "code": "required",
            "details": {
              "text": "Published concept maps SHOULD conform to the ShareableConceptMap profile, which says that the element ConceptMap.experimental is mandatory, but it is not present"
            },
            "expression": [
              "ConceptMap/SNOMEDLOINCtoSNOMEDUK: ConceptMap"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 3403
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '612991010000106' in the system http://snomed.info/sct is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/SNOMEDLOINCtoSNOMEDUK: ConceptMap.group[0].element[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 3495
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '613061010000108' in the system http://snomed.info/sct is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/SNOMEDLOINCtoSNOMEDUK: ConceptMap.group[0].element[1].code"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/Condition-EPIC-OBX-2",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Condition-EPIC-OBX-2",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 15
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 4
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              }
            ],
            "severity": "error",
            "code": "exception",
            "details": {
              "text": "Error from https://tx.fhir.org/r4: The filter \"constraint = descendantOf 404684003 OR descendantOf 413350009 OR descendantOf 272379006\" from the value set https://fhir.hl7.org.uk/ValueSet/UKCore-ConditionCode was not understood in the context of http://snomed.info/sct (1)"
            },
            "expression": [
              "Condition/EPIC-OBX-2: Condition.code"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/Condition-c8f82825-e4cb-4e1f-b728-3fd2808e93db",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Condition-c8f82825-e4cb-4e1f-b728-3fd2808e93db",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 14
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 4
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Coding_has_no_system__cannot_validate"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Coding has no system. A code with no system has no defined meaning, and it cannot be validated. A system should be provided"
            },
            "expression": [
              "Condition/c8f82825-e4cb-4e1f-b728-3fd2808e93db: Condition.clinicalStatus.coding[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 14
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 4
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Terminology_TX_NoValid_1_CC"
              }
            ],
            "severity": "error",
            "code": "code-invalid",
            "details": {
              "text": "None of the codings provided are in the value set 'Condition Clinical Status Codes' (http://hl7.org/fhir/ValueSet/condition-clinical|4.0.1), and a coding from this value set is required) (codes = null#final)"
            },
            "expression": [
              "Condition/c8f82825-e4cb-4e1f-b728-3fd2808e93db: Condition.clinicalStatus"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 21
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 4
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Coding_has_no_system__cannot_validate"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Coding has no system. A code with no system has no defined meaning, and it cannot be validated. A system should be provided"
            },
            "expression": [
              "Condition/c8f82825-e4cb-4e1f-b728-3fd2808e93db: Condition.verificationStatus.coding[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 21
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 4
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Terminology_TX_NoValid_1_CC"
              }
            ],
            "severity": "error",
            "code": "code-invalid",
            "details": {
              "text": "None of the codings provided are in the value set 'ConditionVerificationStatus' (http://hl7.org/fhir/ValueSet/condition-ver-status|4.0.1), and a coding from this value set is required) (codes = null#confirmed)"
            },
            "expression": [
              "Condition/c8f82825-e4cb-4e1f-b728-3fd2808e93db: Condition.verificationStatus"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 40
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 4
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              }
            ],
            "severity": "error",
            "code": "exception",
            "details": {
              "text": "Error from https://tx.fhir.org/r4: The filter \"constraint = descendantOf 404684003 OR descendantOf 413350009 OR descendantOf 272379006\" from the value set https://fhir.hl7.org.uk/ValueSet/UKCore-ConditionCode was not understood in the context of http://snomed.info/sct (1)"
            },
            "expression": [
              "Condition/c8f82825-e4cb-4e1f-b728-3fd2808e93db: Condition.code"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/Condition-d6c19529-a64e-476b-b896-303abec26a79",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Condition-d6c19529-a64e-476b-b896-303abec26a79",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 14
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 4
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Coding_has_no_system__cannot_validate"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Coding has no system. A code with no system has no defined meaning, and it cannot be validated. A system should be provided"
            },
            "expression": [
              "Condition/d6c19529-a64e-476b-b896-303abec26a79: Condition.clinicalStatus.coding[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 14
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 4
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Terminology_TX_NoValid_1_CC"
              }
            ],
            "severity": "error",
            "code": "code-invalid",
            "details": {
              "text": "None of the codings provided are in the value set 'Condition Clinical Status Codes' (http://hl7.org/fhir/ValueSet/condition-clinical|4.0.1), and a coding from this value set is required) (codes = null#final)"
            },
            "expression": [
              "Condition/d6c19529-a64e-476b-b896-303abec26a79: Condition.clinicalStatus"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 21
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 4
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Coding_has_no_system__cannot_validate"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Coding has no system. A code with no system has no defined meaning, and it cannot be validated. A system should be provided"
            },
            "expression": [
              "Condition/d6c19529-a64e-476b-b896-303abec26a79: Condition.verificationStatus.coding[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 21
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 4
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Terminology_TX_NoValid_1_CC"
              }
            ],
            "severity": "error",
            "code": "code-invalid",
            "details": {
              "text": "None of the codings provided are in the value set 'ConditionVerificationStatus' (http://hl7.org/fhir/ValueSet/condition-ver-status|4.0.1), and a coding from this value set is required) (codes = null#confirmed)"
            },
            "expression": [
              "Condition/d6c19529-a64e-476b-b896-303abec26a79: Condition.verificationStatus"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 40
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 4
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              }
            ],
            "severity": "error",
            "code": "exception",
            "details": {
              "text": "Error from https://tx.fhir.org/r4: The filter \"constraint = descendantOf 404684003 OR descendantOf 413350009 OR descendantOf 272379006\" from the value set https://fhir.hl7.org.uk/ValueSet/UKCore-ConditionCode was not understood in the context of http://snomed.info/sct (1)"
            },
            "expression": [
              "Condition/d6c19529-a64e-476b-b896-303abec26a79: Condition.code"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/DiagnosticReport-DiagnosticReportGenomicsReport",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "DiagnosticReport-DiagnosticReportGenomicsReport"
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/DocumentReference-94bf65ba-cd6c-4601-b339-6d547f424646",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "DocumentReference-94bf65ba-cd6c-4601-b339-6d547f424646"
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/DocumentReference-a293b4a6-e46b-4402-9b2b-d9517afc7137",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "DocumentReference-a293b4a6-e46b-4402-9b2b-d9517afc7137"
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/Encounter-984b8a89-4194-4eb4-a7ea-ca8049ebeea3",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Encounter-984b8a89-4194-4eb4-a7ea-ca8049ebeea3",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 63
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 4
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TERMINOLOGY_TX_SYSTEM_NO_CODE"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "A code with no system has no defined meaning, and it cannot be validated. A system should be provided"
            },
            "expression": [
              "Encounter/984b8a89-4194-4eb4-a7ea-ca8049ebeea3: Encounter.class"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/ExampleScenario-BiopsyProcedure",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ExampleScenario-BiopsyProcedure",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 2232
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Validation_VAL_Profile_Minimum"
              }
            ],
            "severity": "error",
            "code": "structure",
            "details": {
              "text": "ExampleScenario.instance.version.description: minimum required = 1, but only found 0 (from http://hl7.org/fhir/StructureDefinition/ExampleScenario|4.0.1)"
            },
            "expression": [
              "ExampleScenario/BiopsyProcedure: ExampleScenario.instance[6].version[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 3798
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_String_WS"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "value should not start or finish with whitespace 'Complete Admission Form. '"
            },
            "expression": [
              "ExampleScenario/BiopsyProcedure: ExampleScenario.process[0].step[2].operation.name"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 4211
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_String_WS"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "value should not start or finish with whitespace 'Complete Admission Form. '"
            },
            "expression": [
              "ExampleScenario/BiopsyProcedure: ExampleScenario.process[0].step[3].operation.name"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 5940
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ExampleScenario#esc-0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: esc-0: 'Name should be usable as an identifier for the module by machine processing applications such as code generation (name.matches('[A-Z]([A-Za-z0-9_]){0,254}'))'"
            },
            "expression": [
              "ExampleScenario/BiopsyProcedure: ExampleScenario"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/ExampleScenario-ClinicalAndGenomicWorkflow",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ExampleScenario-ClinicalAndGenomicWorkflow",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1612
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Validation_VAL_Profile_Minimum"
              }
            ],
            "severity": "error",
            "code": "structure",
            "details": {
              "text": "ExampleScenario.instance.version.description: minimum required = 1, but only found 0 (from http://hl7.org/fhir/StructureDefinition/ExampleScenario|4.0.1)"
            },
            "expression": [
              "ExampleScenario/ClinicalAndGenomicWorkflow: ExampleScenario.instance[0].version[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 2110
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Validation_VAL_Profile_Minimum"
              }
            ],
            "severity": "error",
            "code": "structure",
            "details": {
              "text": "ExampleScenario.instance.version.description: minimum required = 1, but only found 0 (from http://hl7.org/fhir/StructureDefinition/ExampleScenario|4.0.1)"
            },
            "expression": [
              "ExampleScenario/ClinicalAndGenomicWorkflow: ExampleScenario.instance[1].version[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 2578
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Validation_VAL_Profile_Minimum"
              }
            ],
            "severity": "error",
            "code": "structure",
            "details": {
              "text": "ExampleScenario.instance.version.description: minimum required = 1, but only found 0 (from http://hl7.org/fhir/StructureDefinition/ExampleScenario|4.0.1)"
            },
            "expression": [
              "ExampleScenario/ClinicalAndGenomicWorkflow: ExampleScenario.instance[2].version[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 3087
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Validation_VAL_Profile_Minimum"
              }
            ],
            "severity": "error",
            "code": "structure",
            "details": {
              "text": "ExampleScenario.instance.version.description: minimum required = 1, but only found 0 (from http://hl7.org/fhir/StructureDefinition/ExampleScenario|4.0.1)"
            },
            "expression": [
              "ExampleScenario/ClinicalAndGenomicWorkflow: ExampleScenario.instance[3].version[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 3609
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Validation_VAL_Profile_Minimum"
              }
            ],
            "severity": "error",
            "code": "structure",
            "details": {
              "text": "ExampleScenario.instance.version.description: minimum required = 1, but only found 0 (from http://hl7.org/fhir/StructureDefinition/ExampleScenario|4.0.1)"
            },
            "expression": [
              "ExampleScenario/ClinicalAndGenomicWorkflow: ExampleScenario.instance[4].version[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 5101
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_String_WS"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "value should not start or finish with whitespace 'Family History for Son Leeds is added to Genomic CDR '"
            },
            "expression": [
              "ExampleScenario/ClinicalAndGenomicWorkflow: ExampleScenario.process[2].step[0].operation.name"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 5440
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ExampleScenario#esc-0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: esc-0: 'Name should be usable as an identifier for the module by machine processing applications such as code generation (name.matches('[A-Z]([A-Za-z0-9_]){0,254}'))'"
            },
            "expression": [
              "ExampleScenario/ClinicalAndGenomicWorkflow: ExampleScenario"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/ExampleScenario-GenomicTestOrderProcess",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ExampleScenario-GenomicTestOrderProcess",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 2149
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Validation_VAL_Profile_Minimum"
              }
            ],
            "severity": "error",
            "code": "structure",
            "details": {
              "text": "ExampleScenario.instance.version.description: minimum required = 1, but only found 0 (from http://hl7.org/fhir/StructureDefinition/ExampleScenario|4.0.1)"
            },
            "expression": [
              "ExampleScenario/GenomicTestOrderProcess: ExampleScenario.instance[1].version[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 3002
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Validation_VAL_Profile_Minimum"
              }
            ],
            "severity": "error",
            "code": "structure",
            "details": {
              "text": "ExampleScenario.instance.version.description: minimum required = 1, but only found 0 (from http://hl7.org/fhir/StructureDefinition/ExampleScenario|4.0.1)"
            },
            "expression": [
              "ExampleScenario/GenomicTestOrderProcess: ExampleScenario.instance[5].version[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 3720
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Validation_VAL_Profile_Minimum"
              }
            ],
            "severity": "error",
            "code": "structure",
            "details": {
              "text": "ExampleScenario.instance.version.description: minimum required = 1, but only found 0 (from http://hl7.org/fhir/StructureDefinition/ExampleScenario|4.0.1)"
            },
            "expression": [
              "ExampleScenario/GenomicTestOrderProcess: ExampleScenario.instance[8].version[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 4944
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_String_WS"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "value should not start or finish with whitespace 'Complete Genomic Test Order Form. '"
            },
            "expression": [
              "ExampleScenario/GenomicTestOrderProcess: ExampleScenario.process[0].step[2].operation.name"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 7535
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ExampleScenario#esc-0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: esc-0: 'Name should be usable as an identifier for the module by machine processing applications such as code generation (name.matches('[A-Z]([A-Za-z0-9_]){0,254}'))'"
            },
            "expression": [
              "ExampleScenario/GenomicTestOrderProcess: ExampleScenario"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/ExampleScenario-GenomicTestReportProcess",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ExampleScenario-GenomicTestReportProcess",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 2514
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Validation_VAL_Profile_Minimum"
              }
            ],
            "severity": "error",
            "code": "structure",
            "details": {
              "text": "ExampleScenario.instance.version.description: minimum required = 1, but only found 0 (from http://hl7.org/fhir/StructureDefinition/ExampleScenario|4.0.1)"
            },
            "expression": [
              "ExampleScenario/GenomicTestReportProcess: ExampleScenario.instance[4].version[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 3310
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Validation_VAL_Profile_Minimum"
              }
            ],
            "severity": "error",
            "code": "structure",
            "details": {
              "text": "ExampleScenario.instance.version.description: minimum required = 1, but only found 0 (from http://hl7.org/fhir/StructureDefinition/ExampleScenario|4.0.1)"
            },
            "expression": [
              "ExampleScenario/GenomicTestReportProcess: ExampleScenario.instance[6].version[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 5844
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ExampleScenario#esc-0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: esc-0: 'Name should be usable as an identifier for the module by machine processing applications such as code generation (name.matches('[A-Z]([A-Za-z0-9_]){0,254}'))'"
            },
            "expression": [
              "ExampleScenario/GenomicTestReportProcess: ExampleScenario"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/FamilyMemberHistory-074ea905-8d91-452c-af3c-15b5b860fdb2",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "FamilyMemberHistory-074ea905-8d91-452c-af3c-15b5b860fdb2",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 43
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 4
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Coding_has_no_system__cannot_validate"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Coding has no system. A code with no system has no defined meaning, and it cannot be validated. A system should be provided"
            },
            "expression": [
              "FamilyMemberHistory/074ea905-8d91-452c-af3c-15b5b860fdb2: FamilyMemberHistory.sex.coding[0]"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/FamilyMemberHistory-c76b8bc2-ec36-4ce1-a2ea-8c57215115e2",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "FamilyMemberHistory-c76b8bc2-ec36-4ce1-a2ea-8c57215115e2",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 31
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 4
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Coding_has_no_system__cannot_validate"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Coding has no system. A code with no system has no defined meaning, and it cannot be validated. A system should be provided"
            },
            "expression": [
              "FamilyMemberHistory/c76b8bc2-ec36-4ce1-a2ea-8c57215115e2: FamilyMemberHistory.sex.coding[0]"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/MessageDefinition-laboratory-order",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "MessageDefinition-laboratory-order"
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/MessageDefinition-patient-encounter",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "MessageDefinition-patient-encounter"
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/MessageDefinition-patient-identity",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "MessageDefinition-patient-identity"
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/MessageDefinition-unsolicited-observation",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "MessageDefinition-unsolicited-observation"
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/MessageHeader-MessageHeaderGenomicOrder",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "MessageHeader-MessageHeaderGenomicOrder"
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/MessageHeader-MessageHeaderGenomicOrderReplyFatal",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "MessageHeader-MessageHeaderGenomicOrderReplyFatal"
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/MessageHeader-MessageHeaderGenomicOrderReplyFatalAcknowledge",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "MessageHeader-MessageHeaderGenomicOrderReplyFatalAcknowledge"
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/MessageHeader-MessageHeaderGenomicOrderReplyOk",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "MessageHeader-MessageHeaderGenomicOrderReplyOk"
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/MessageHeader-MessageHeaderGenomicOrderReplyTransient",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "MessageHeader-MessageHeaderGenomicOrderReplyTransient"
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/MessageHeader-MessageHeaderGenomicReport",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "MessageHeader-MessageHeaderGenomicReport"
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/MessageHeader-MessageHeaderGenomicReportAck",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "MessageHeader-MessageHeaderGenomicReportAck"
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/MessageHeader-MessageHeaderPatient",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "MessageHeader-MessageHeaderPatient"
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/Observation-4490c092-c78c-480a-8cb7-653b70113fd5",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Observation-4490c092-c78c-480a-8cb7-653b70113fd5",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 40
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 4
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "UNKNOWN_CODESYSTEM"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'http://snomed.info/sct' could not be found, so the code cannot be validated"
            },
            "expression": [
              "Observation/4490c092-c78c-480a-8cb7-653b70113fd5: Observation.code.coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 2
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.eu/fhir/laboratory/StructureDefinition/Observation-resultslab-eu-lab#eu-lab-1"
              }
            ],
            "severity": "error",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eu-lab-1: 'If observation status is other then \"registered\" or \"cancelled\", at least one of these Observation elements shall be provided:  \"value\", \"dataAbsentReason\", \"hasMember\" or \"component\" ((status in ('registered'|'cancelled')) or value.exists() or hasMember.exists() or component.exists() or dataAbsentReason.exists())' (defined in http://hl7.eu/fhir/laboratory/StructureDefinition/Observation-resultslab-eu-lab)"
            },
            "expression": [
              "Observation/4490c092-c78c-480a-8cb7-653b70113fd5: Observation"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/Observation-6beb613f-d303-42af-b025-86e8e0872061",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Observation-6beb613f-d303-42af-b025-86e8e0872061",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 88
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "UNKNOWN_CODE_IN_FRAGMENT"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "Unknown Code 'R210' in the CodeSystem 'https://fhir.nwgenomics.nhs.uk/CodeSystem/GenomicClinicalIndication' version '0.1.0' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"
            },
            "expression": [
              "Observation/6beb613f-d303-42af-b025-86e8e0872061: Observation.component[1].value.ofType(CodeableConcept).coding[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 88
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Unknown_Code_in_Version"
              }
            ],
            "severity": "error",
            "code": "code-invalid",
            "details": {
              "text": "Unknown code '1365861003' in the CodeSystem 'http://snomed.info/sct' version 'http://snomed.info/sct/83821000000107/version/20230412' (UK Edition)"
            },
            "expression": [
              "Observation/6beb613f-d303-42af-b025-86e8e0872061: Observation.component[1].value.ofType(CodeableConcept).coding[1].code"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/Observation-8385c2fd-313d-4fd5-b98e-d5ea4bae6f99",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Observation-8385c2fd-313d-4fd5-b98e-d5ea4bae6f99",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 53
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 4
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Unknown_Code_in_Version"
              }
            ],
            "severity": "error",
            "code": "code-invalid",
            "details": {
              "text": "Unknown code 'LA26398' in the CodeSystem 'http://loinc.org' version '2.81'"
            },
            "expression": [
              "Observation/8385c2fd-313d-4fd5-b98e-d5ea4bae6f99: Observation.method.coding[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 73
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "Unable to check whether the code is in the value set '' because the code system http://www.genenames.org was not found"
            },
            "expression": [
              "Observation/8385c2fd-313d-4fd5-b98e-d5ea4bae6f99: Observation.component[0].value.ofType(CodeableConcept)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 73
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"
            },
            "expression": [
              "Observation/8385c2fd-313d-4fd5-b98e-d5ea4bae6f99: Observation.component[0].value.ofType(CodeableConcept).coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 93
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"
            },
            "expression": [
              "Observation/8385c2fd-313d-4fd5-b98e-d5ea4bae6f99: Observation.component[1].value.ofType(CodeableConcept)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 93
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"
            },
            "expression": [
              "Observation/8385c2fd-313d-4fd5-b98e-d5ea4bae6f99: Observation.component[1].value.ofType(CodeableConcept).coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 112
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Unknown_Code_in_Version"
              }
            ],
            "severity": "error",
            "code": "code-invalid",
            "details": {
              "text": "Unknown code 'NC_000003.11' in the CodeSystem 'http://varnomen.hgvs.org' version '2.0'"
            },
            "expression": [
              "Observation/8385c2fd-313d-4fd5-b98e-d5ea4bae6f99: Observation.component[2].value.ofType(CodeableConcept).coding[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 112
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Terminology_TX_NoValid_1_CC"
              }
            ],
            "severity": "error",
            "code": "code-invalid",
            "details": {
              "text": "None of the codings provided are in the value set 'Human Genome Variation Society (HGVS) Nomenclature' (http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs|3.0.0), and a coding from this value set is required) (codes = http://varnomen.hgvs.org#NC_000003.11)"
            },
            "expression": [
              "Observation/8385c2fd-313d-4fd5-b98e-d5ea4bae6f99: Observation.component[2].value.ofType(CodeableConcept)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 131
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"
            },
            "expression": [
              "Observation/8385c2fd-313d-4fd5-b98e-d5ea4bae6f99: Observation.component[3].value.ofType(CodeableConcept)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 131
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"
            },
            "expression": [
              "Observation/8385c2fd-313d-4fd5-b98e-d5ea4bae6f99: Observation.component[3].value.ofType(CodeableConcept).coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 201
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Display_Name_for__should_be_one_of__instead_of"
              }
            ],
            "severity": "error",
            "code": "invalid",
            "details": {
              "text": "Wrong Display Name 'Genomic ref allele' for http://loinc.org#69547-8. Valid display is one of 4 choices: 'Genomic ref allele [ID]' (en-US), 'Genomic ref allele [ID]' (en-US), 'Ref nucleotide' (en-US) or 'Reference nucleotide, Blood or tissue specimen' (en-US) (for the language(s) 'en-GB')"
            },
            "expression": [
              "Observation/8385c2fd-313d-4fd5-b98e-d5ea4bae6f99: Observation.component[7].code.coding[0].display"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/Observation-EPIC-OBR-1",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Observation-EPIC-OBR-1",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 26
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 4
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "UNKNOWN_CODE_IN_FRAGMENT"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "Unknown Code 'GENEAP' in the CodeSystem 'https://fhir.nwgenomics.nhs.uk/CodeSystem/MFTQuestionIds' version '0.1.0' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"
            },
            "expression": [
              "Observation/EPIC-OBR-1: Observation.code.coding[0].code"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/Observation-EPIC-OBX-10",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Observation-EPIC-OBX-10",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 26
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 4
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "UNKNOWN_CODE_IN_FRAGMENT"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "Unknown Code '230037' in the CodeSystem 'https://fhir.nwgenomics.nhs.uk/CodeSystem/MFTQuestionIds' version '0.1.0' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"
            },
            "expression": [
              "Observation/EPIC-OBX-10: Observation.code.coding[0].code"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/Observation-EPIC-OBX-11",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Observation-EPIC-OBX-11",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 26
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 4
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "UNKNOWN_CODE_IN_FRAGMENT"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "Unknown Code '230039' in the CodeSystem 'https://fhir.nwgenomics.nhs.uk/CodeSystem/MFTQuestionIds' version '0.1.0' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"
            },
            "expression": [
              "Observation/EPIC-OBX-11: Observation.code.coding[0].code"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/Observation-EPIC-OBX-4",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Observation-EPIC-OBX-4",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 26
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 4
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "UNKNOWN_CODE_IN_FRAGMENT"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "Unknown Code '230016' in the CodeSystem 'https://fhir.nwgenomics.nhs.uk/CodeSystem/MFTQuestionIds' version '0.1.0' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"
            },
            "expression": [
              "Observation/EPIC-OBX-4: Observation.code.coding[0].code"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/Observation-EPIC-OBX-6",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Observation-EPIC-OBX-6",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 26
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 4
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "UNKNOWN_CODE_IN_FRAGMENT"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "Unknown Code '231284' in the CodeSystem 'https://fhir.nwgenomics.nhs.uk/CodeSystem/MFTQuestionIds' version '0.1.0' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"
            },
            "expression": [
              "Observation/EPIC-OBX-6: Observation.code.coding[0].code"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/Observation-EPIC-OBX-7",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Observation-EPIC-OBX-7",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 26
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 4
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "UNKNOWN_CODE_IN_FRAGMENT"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "Unknown Code '231285' in the CodeSystem 'https://fhir.nwgenomics.nhs.uk/CodeSystem/MFTQuestionIds' version '0.1.0' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"
            },
            "expression": [
              "Observation/EPIC-OBX-7: Observation.code.coding[0].code"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/Observation-EPIC-OBX-8",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Observation-EPIC-OBX-8",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 26
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 4
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "UNKNOWN_CODE_IN_FRAGMENT"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "Unknown Code '230027' in the CodeSystem 'https://fhir.nwgenomics.nhs.uk/CodeSystem/MFTQuestionIds' version '0.1.0' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"
            },
            "expression": [
              "Observation/EPIC-OBX-8: Observation.code.coding[0].code"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/Observation-OBX-Consanguinity",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Observation-OBX-Consanguinity",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 26
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 4
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "UNKNOWN_CODESYSTEM"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'http://snomed.info/sct' could not be found, so the code cannot be validated"
            },
            "expression": [
              "Observation/OBX-Consanguinity: Observation.code.coding[0].system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/Observation-OBX-GenomicReferralCategory",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Observation-OBX-GenomicReferralCategory",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 26
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 4
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "UNKNOWN_CODE_IN_FRAGMENT"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "Unknown Code '230056' in the CodeSystem 'https://fhir.nwgenomics.nhs.uk/CodeSystem/MFTQuestionIds' version '0.1.0' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"
            },
            "expression": [
              "Observation/OBX-GenomicReferralCategory: Observation.code.coding[0].code"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/Observation-OBX-HighInfectionRiskSample",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Observation-OBX-HighInfectionRiskSample",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 26
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 4
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "UNKNOWN_CODESYSTEM"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'http://snomed.info/sct' could not be found, so the code cannot be validated"
            },
            "expression": [
              "Observation/OBX-HighInfectionRiskSample: Observation.code.coding[0].system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/Observation-OBX-InformedConsent",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Observation-OBX-InformedConsent",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 26
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 4
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "UNKNOWN_CODESYSTEM"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'http://snomed.info/sct' could not be found, so the code cannot be validated"
            },
            "expression": [
              "Observation/OBX-InformedConsent: Observation.code.coding[0].system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/Observation-OBX-MCV",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Observation-OBX-MCV",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 33
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 4
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "UNKNOWN_CODESYSTEM"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'http://snomed.info/sct' could not be found, so the code cannot be validated"
            },
            "expression": [
              "Observation/OBX-MCV: Observation.code.coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 33
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 4
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Display_Name_for__should_be_one_of__instead_of"
              }
            ],
            "severity": "error",
            "code": "invalid",
            "details": {
              "text": "Wrong Display Name 'MCV [Entitic mean volume] in Red Blood Cells by Automated count' for http://loinc.org#787-2. Valid display is one of 4 choices: 'MCV [Entitic volume] by Automated count' (en-US), 'MCV [Entitic volume] by Automated count' (en-US), 'MCV RBC Auto' (en-US) or 'Mean Corpuscular Volume (MCV), Red blood cells' (en-US) (for the language(s) 'en-GB')"
            },
            "expression": [
              "Observation/OBX-MCV: Observation.code.coding[3].display"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/Observation-OBX-OrderTrackingNumber",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Observation-OBX-OrderTrackingNumber"
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/Observation-OBX-Pregnancy",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Observation-OBX-Pregnancy",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 26
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 4
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "UNKNOWN_CODESYSTEM"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'http://snomed.info/sct' could not be found, so the code cannot be validated"
            },
            "expression": [
              "Observation/OBX-Pregnancy: Observation.code.coding[0].system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/Observation-OBX-PregnancyExpectedDeliveryDate",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Observation-OBX-PregnancyExpectedDeliveryDate",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 26
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 4
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "UNKNOWN_CODESYSTEM"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'http://snomed.info/sct' could not be found, so the code cannot be validated"
            },
            "expression": [
              "Observation/OBX-PregnancyExpectedDeliveryDate: Observation.code.coding[0].system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/Observation-OBX-SupervisingClinician",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Observation-OBX-SupervisingClinician",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 26
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 4
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "UNKNOWN_CODE_IN_FRAGMENT"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "Unknown Code 'unknown' in the CodeSystem 'https://fhir.nwgenomics.nhs.uk/CodeSystem/MFTQuestionIds' version '0.1.0' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"
            },
            "expression": [
              "Observation/OBX-SupervisingClinician: Observation.code.coding[0].code"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/Observation-a954a98c-f427-4968-9022-8b760de66628",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Observation-a954a98c-f427-4968-9022-8b760de66628",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 88
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "UNKNOWN_CODE_IN_FRAGMENT"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "Unknown Code 'R185' in the CodeSystem 'https://fhir.nwgenomics.nhs.uk/CodeSystem/GenomicClinicalIndication' version '0.1.0' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"
            },
            "expression": [
              "Observation/a954a98c-f427-4968-9022-8b760de66628: Observation.component[1].value.ofType(CodeableConcept).coding[0].code"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/Observation-bca547c1-78a5-41be-8cfc-03c05805ac85",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Observation-bca547c1-78a5-41be-8cfc-03c05805ac85",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 64
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "Unable to check whether the code is in the value set '' because the code system http://www.genenames.org was not found"
            },
            "expression": [
              "Observation/bca547c1-78a5-41be-8cfc-03c05805ac85: Observation.component[0].value.ofType(CodeableConcept)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 64
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"
            },
            "expression": [
              "Observation/bca547c1-78a5-41be-8cfc-03c05805ac85: Observation.component[0].value.ofType(CodeableConcept).coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 84
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"
            },
            "expression": [
              "Observation/bca547c1-78a5-41be-8cfc-03c05805ac85: Observation.component[1].value.ofType(CodeableConcept)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 84
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"
            },
            "expression": [
              "Observation/bca547c1-78a5-41be-8cfc-03c05805ac85: Observation.component[1].value.ofType(CodeableConcept).coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 103
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Unknown_Code_in_Version"
              }
            ],
            "severity": "error",
            "code": "code-invalid",
            "details": {
              "text": "Unknown code 'NC_000007.13' in the CodeSystem 'http://varnomen.hgvs.org' version '2.0'"
            },
            "expression": [
              "Observation/bca547c1-78a5-41be-8cfc-03c05805ac85: Observation.component[2].value.ofType(CodeableConcept).coding[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 103
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Terminology_TX_NoValid_1_CC"
              }
            ],
            "severity": "error",
            "code": "code-invalid",
            "details": {
              "text": "None of the codings provided are in the value set 'Human Genome Variation Society (HGVS) Nomenclature' (http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs|3.0.0), and a coding from this value set is required) (codes = http://varnomen.hgvs.org#NC_000007.13)"
            },
            "expression": [
              "Observation/bca547c1-78a5-41be-8cfc-03c05805ac85: Observation.component[2].value.ofType(CodeableConcept)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 173
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Display_Name_for__should_be_one_of__instead_of"
              }
            ],
            "severity": "error",
            "code": "invalid",
            "details": {
              "text": "Wrong Display Name 'Genomic ref allele' for http://loinc.org#69547-8. Valid display is one of 4 choices: 'Genomic ref allele [ID]' (en-US), 'Genomic ref allele [ID]' (en-US), 'Ref nucleotide' (en-US) or 'Reference nucleotide, Blood or tissue specimen' (en-US) (for the language(s) 'en-GB')"
            },
            "expression": [
              "Observation/bca547c1-78a5-41be-8cfc-03c05805ac85: Observation.component[6].code.coding[0].display"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/OperationDefinition-ProcessMessage",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "OperationDefinition-ProcessMessage"
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/Organization-699X0",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Organization-699X0"
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/Organization-R0A",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Organization-R0A"
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/Parameters-exp-params",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Parameters-exp-params"
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/Patient-Patient-Birmingham",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Patient-Patient-Birmingham"
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/Patient-Patient-Bolton",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Patient-Patient-Bolton"
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/Patient-Patient-Congleton",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Patient-Patient-Congleton"
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/Patient-Patient-Lancaster",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Patient-Patient-Lancaster"
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/Patient-Patient-Leeds",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Patient-Patient-Leeds"
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/Patient-Patient-Liverpool",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Patient-Patient-Liverpool"
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/Patient-Patient-London",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Patient-Patient-London",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 39
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 66
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'urn:oid:1.2.840.114350.1.13.611.3.7.5.737384.14'"
            },
            "expression": [
              "Patient/Patient-London: Patient.identifier[1].system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/Patient-Patient-Manchester",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Patient-Patient-Manchester",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 39
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 66
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'urn:oid:1.2.840.114350.1.13.611.3.7.5.737384.14'"
            },
            "expression": [
              "Patient/Patient-Manchester: Patient.identifier[1].system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/Patient-Patient-Northwich",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Patient-Patient-Northwich"
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/Patient-Patient-Nottingham",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Patient-Patient-Nottingham"
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/Patient-Patient-OctaviaCHISLETT-9449305552",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Patient-Patient-OctaviaCHISLETT-9449305552",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 57
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 66
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'urn:oid:1.2.840.114350.1.13.611.3.7.5.737384.14'"
            },
            "expression": [
              "Patient/Patient-OctaviaCHISLETT-9449305552: Patient.identifier[2].system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/Patient-Patient-Warrington",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Patient-Patient-Warrington"
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/Patient-Patient-Wrexham",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Patient-Patient-Wrexham"
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/PractitionerRole-59577028-8fcc-4554-8b43-988561d41d9c",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "PractitionerRole-59577028-8fcc-4554-8b43-988561d41d9c"
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/PractitionerRole-ee9b8fcc-c233-43e1-b7fb-b58ce4cf1db8",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "PractitionerRole-ee9b8fcc-c233-43e1-b7fb-b58ce4cf1db8"
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/Procedure-13240a3b-d1db-4f1a-ad7d-b19f23967060",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Procedure-13240a3b-d1db-4f1a-ad7d-b19f23967060",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 25
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 4
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              }
            ],
            "severity": "error",
            "code": "exception",
            "details": {
              "text": "Error from https://tx.fhir.org/r4: The filter \"constraint = descendantOrSelfOf 71388002 OR descendantOrSelfOf 129125009\" from the value set https://fhir.hl7.org.uk/ValueSet/UKCore-ProcedureCode was not understood in the context of http://snomed.info/sct (1)"
            },
            "expression": [
              "Procedure/13240a3b-d1db-4f1a-ad7d-b19f23967060: Procedure.code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 27
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "SLICING_CANNOT_BE_EVALUATED"
              }
            ],
            "severity": "error",
            "code": "processing",
            "details": {
              "text": "Slicing cannot be evaluated: Could not match discriminator (system) for slice Procedure.code.coding:snomedCT in profile https://fhir.nwgenomics.nhs.uk/StructureDefinition/Procedure|0.1.0 - the discriminator [system] does not have fixed value, binding or existence assertions"
            },
            "expression": [
              "Procedure/13240a3b-d1db-4f1a-ad7d-b19f23967060: Procedure.code.coding[0]"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/Procedure-7b362aa5-41a7-4168-94b4-f12dff0dfb2a",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Procedure-7b362aa5-41a7-4168-94b4-f12dff0dfb2a",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 32
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 6
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "UNKNOWN_CODE_IN_FRAGMENT"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "Unknown Code 'R185' in the CodeSystem 'https://fhir.nwgenomics.nhs.uk/CodeSystem/GenomicClinicalIndication' version '0.1.0' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"
            },
            "expression": [
              "Procedure/7b362aa5-41a7-4168-94b4-f12dff0dfb2a: Procedure.reasonCode[0].coding[0].code"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/Procedure-f0036554-cd1a-463c-ac8a-d891ca409af9",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Procedure-f0036554-cd1a-463c-ac8a-d891ca409af9",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 32
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 6
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "UNKNOWN_CODE_IN_FRAGMENT"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "Unknown Code 'R210' in the CodeSystem 'https://fhir.nwgenomics.nhs.uk/CodeSystem/GenomicClinicalIndication' version '0.1.0' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"
            },
            "expression": [
              "Procedure/f0036554-cd1a-463c-ac8a-d891ca409af9: Procedure.reasonCode[0].coding[0].code"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/Questionnaire-GenomicOrderEntryOptionalQuestions",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Questionnaire-GenomicOrderEntryOptionalQuestions",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 95492
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "XHTML_XHTML_DUPLICATE_IDS"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The XHTML  the resource contains more than one node for each of the following node ids and anchor names: item.281269004-designNote (2x)"
            },
            "expression": [
              "Questionnaire/GenomicOrderEntryOptionalQuestions: Questionnaire.text.div"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 96331
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "UNKNOWN_CODE_IN_FRAGMENT"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "Unknown Code '230016' in the CodeSystem 'https://fhir.nwgenomics.nhs.uk/CodeSystem/MFTQuestionIds' version '0.1.0' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"
            },
            "expression": [
              "Questionnaire/GenomicOrderEntryOptionalQuestions: Questionnaire.item[0].item[0].code[1].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 96804
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "UNKNOWN_CODE_IN_FRAGMENT"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "Unknown Code '230017' in the CodeSystem 'https://fhir.nwgenomics.nhs.uk/CodeSystem/MFTQuestionIds' version '0.1.0' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"
            },
            "expression": [
              "Questionnaire/GenomicOrderEntryOptionalQuestions: Questionnaire.item[0].item[1].code[1].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 97285
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "UNKNOWN_CODE_IN_FRAGMENT"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "Unknown Code '230018' in the CodeSystem 'https://fhir.nwgenomics.nhs.uk/CodeSystem/MFTQuestionIds' version '0.1.0' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"
            },
            "expression": [
              "Questionnaire/GenomicOrderEntryOptionalQuestions: Questionnaire.item[0].item[2].code[1].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 97573
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "UNKNOWN_CODE_IN_FRAGMENT"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "Unknown Code '114867' in the CodeSystem 'https://fhir.nwgenomics.nhs.uk/CodeSystem/MFTQuestionIds' version '0.1.0' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"
            },
            "expression": [
              "Questionnaire/GenomicOrderEntryOptionalQuestions: Questionnaire.item[0].item[3].code[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 97879
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "UNKNOWN_CODE_IN_FRAGMENT"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "Unknown Code '230022' in the CodeSystem 'https://fhir.nwgenomics.nhs.uk/CodeSystem/MFTQuestionIds' version '0.1.0' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"
            },
            "expression": [
              "Questionnaire/GenomicOrderEntryOptionalQuestions: Questionnaire.item[0].item[4].code[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 98272
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "UNKNOWN_CODE_IN_FRAGMENT"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "Unknown Code '230039' in the CodeSystem 'https://fhir.nwgenomics.nhs.uk/CodeSystem/MFTQuestionIds' version '0.1.0' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"
            },
            "expression": [
              "Questionnaire/GenomicOrderEntryOptionalQuestions: Questionnaire.item[0].item[5].code[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 98694
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "UNKNOWN_CODE_IN_FRAGMENT"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "Unknown Code '113979' in the CodeSystem 'https://fhir.nwgenomics.nhs.uk/CodeSystem/MFTQuestionIds' version '0.1.0' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"
            },
            "expression": [
              "Questionnaire/GenomicOrderEntryOptionalQuestions: Questionnaire.item[1].item[0].code[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 99142
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "UNKNOWN_CODE_IN_FRAGMENT"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "Unknown Code '230001' in the CodeSystem 'https://fhir.nwgenomics.nhs.uk/CodeSystem/MFTQuestionIds' version '0.1.0' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"
            },
            "expression": [
              "Questionnaire/GenomicOrderEntryOptionalQuestions: Questionnaire.item[1].item[1].code[1].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 99730
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "UNKNOWN_CODE_IN_FRAGMENT"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "Unknown Code '230002' in the CodeSystem 'https://fhir.nwgenomics.nhs.uk/CodeSystem/MFTQuestionIds' version '0.1.0' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"
            },
            "expression": [
              "Questionnaire/GenomicOrderEntryOptionalQuestions: Questionnaire.item[1].item[2].code[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 100028
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "UNKNOWN_CODE_IN_FRAGMENT"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "Unknown Code '230003' in the CodeSystem 'https://fhir.nwgenomics.nhs.uk/CodeSystem/MFTQuestionIds' version '0.1.0' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"
            },
            "expression": [
              "Questionnaire/GenomicOrderEntryOptionalQuestions: Questionnaire.item[1].item[3].code[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 100232
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "UNKNOWN_CODE_IN_FRAGMENT"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "Unknown Code '230004' in the CodeSystem 'https://fhir.nwgenomics.nhs.uk/CodeSystem/MFTQuestionIds' version '0.1.0' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"
            },
            "expression": [
              "Questionnaire/GenomicOrderEntryOptionalQuestions: Questionnaire.item[1].item[4].code[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 100443
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "UNKNOWN_CODE_IN_FRAGMENT"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "Unknown Code '230005' in the CodeSystem 'https://fhir.nwgenomics.nhs.uk/CodeSystem/MFTQuestionIds' version '0.1.0' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"
            },
            "expression": [
              "Questionnaire/GenomicOrderEntryOptionalQuestions: Questionnaire.item[1].item[5].code[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 100901
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "UNKNOWN_CODE_IN_FRAGMENT"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "Unknown Code '230019' in the CodeSystem 'https://fhir.nwgenomics.nhs.uk/CodeSystem/MFTQuestionIds' version '0.1.0' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"
            },
            "expression": [
              "Questionnaire/GenomicOrderEntryOptionalQuestions: Questionnaire.item[1].item[6].code[1].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 101578
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "UNKNOWN_CODE_IN_FRAGMENT"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "Unknown Code '230020' in the CodeSystem 'https://fhir.nwgenomics.nhs.uk/CodeSystem/MFTQuestionIds' version '0.1.0' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"
            },
            "expression": [
              "Questionnaire/GenomicOrderEntryOptionalQuestions: Questionnaire.item[1].item[7].code[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 102107
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "UNKNOWN_CODE_IN_FRAGMENT"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "Unknown Code '230028' in the CodeSystem 'https://fhir.nwgenomics.nhs.uk/CodeSystem/MFTQuestionIds' version '0.1.0' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"
            },
            "expression": [
              "Questionnaire/GenomicOrderEntryOptionalQuestions: Questionnaire.item[1].item[8].code[2].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 102752
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "UNKNOWN_CODE_IN_FRAGMENT"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "Unknown Code '230063' in the CodeSystem 'https://fhir.nwgenomics.nhs.uk/CodeSystem/MFTQuestionIds' version '0.1.0' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"
            },
            "expression": [
              "Questionnaire/GenomicOrderEntryOptionalQuestions: Questionnaire.item[1].item[9].code[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 103137
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "UNKNOWN_CODE_IN_FRAGMENT"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "Unknown Code '230021' in the CodeSystem 'https://fhir.nwgenomics.nhs.uk/CodeSystem/MFTQuestionIds' version '0.1.0' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"
            },
            "expression": [
              "Questionnaire/GenomicOrderEntryOptionalQuestions: Questionnaire.item[1].item[10].code[1].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 103815
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "UNKNOWN_CODE_IN_FRAGMENT"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "Unknown Code '230037' in the CodeSystem 'https://fhir.nwgenomics.nhs.uk/CodeSystem/MFTQuestionIds' version '0.1.0' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"
            },
            "expression": [
              "Questionnaire/GenomicOrderEntryOptionalQuestions: Questionnaire.item[1].item[11].code[1].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 104396
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "UNKNOWN_CODE_IN_FRAGMENT"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "Unknown Code '102313' in the CodeSystem 'https://fhir.nwgenomics.nhs.uk/CodeSystem/MFTQuestionIds' version '0.1.0' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"
            },
            "expression": [
              "Questionnaire/GenomicOrderEntryOptionalQuestions: Questionnaire.item[2].item[0].code[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 104689
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "UNKNOWN_CODE_IN_FRAGMENT"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "Unknown Code '230022' in the CodeSystem 'https://fhir.nwgenomics.nhs.uk/CodeSystem/MFTQuestionIds' version '0.1.0' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"
            },
            "expression": [
              "Questionnaire/GenomicOrderEntryOptionalQuestions: Questionnaire.item[2].item[1].code[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 104964
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "UNKNOWN_CODE_IN_FRAGMENT"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "Unknown Code '230027' in the CodeSystem 'https://fhir.nwgenomics.nhs.uk/CodeSystem/MFTQuestionIds' version '0.1.0' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"
            },
            "expression": [
              "Questionnaire/GenomicOrderEntryOptionalQuestions: Questionnaire.item[2].item[2].code[1].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 105408
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "UNKNOWN_CODE_IN_FRAGMENT"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "Unknown Code '230029' in the CodeSystem 'https://fhir.nwgenomics.nhs.uk/CodeSystem/MFTQuestionIds' version '0.1.0' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"
            },
            "expression": [
              "Questionnaire/GenomicOrderEntryOptionalQuestions: Questionnaire.item[2].item[3].code[2].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 106065
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "UNKNOWN_CODE_IN_FRAGMENT"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "Unknown Code '230030' in the CodeSystem 'https://fhir.nwgenomics.nhs.uk/CodeSystem/MFTQuestionIds' version '0.1.0' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"
            },
            "expression": [
              "Questionnaire/GenomicOrderEntryOptionalQuestions: Questionnaire.item[2].item[4].item[0].code[1].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 106489
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "UNKNOWN_CODE_IN_FRAGMENT"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "Unknown Code '230031' in the CodeSystem 'https://fhir.nwgenomics.nhs.uk/CodeSystem/MFTQuestionIds' version '0.1.0' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"
            },
            "expression": [
              "Questionnaire/GenomicOrderEntryOptionalQuestions: Questionnaire.item[2].item[4].item[1].code[1].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 106806
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "UNKNOWN_CODE_IN_FRAGMENT"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "Unknown Code '230032' in the CodeSystem 'https://fhir.nwgenomics.nhs.uk/CodeSystem/MFTQuestionIds' version '0.1.0' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"
            },
            "expression": [
              "Questionnaire/GenomicOrderEntryOptionalQuestions: Questionnaire.item[2].item[4].item[2].code[1].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 107108
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "UNKNOWN_CODE_IN_FRAGMENT"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "Unknown Code '230033' in the CodeSystem 'https://fhir.nwgenomics.nhs.uk/CodeSystem/MFTQuestionIds' version '0.1.0' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"
            },
            "expression": [
              "Questionnaire/GenomicOrderEntryOptionalQuestions: Questionnaire.item[2].item[4].item[3].code[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 107443
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "UNKNOWN_CODE_IN_FRAGMENT"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "Unknown Code '230034' in the CodeSystem 'https://fhir.nwgenomics.nhs.uk/CodeSystem/MFTQuestionIds' version '0.1.0' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"
            },
            "expression": [
              "Questionnaire/GenomicOrderEntryOptionalQuestions: Questionnaire.item[2].item[5].item[0].code[1].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 107824
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "UNKNOWN_CODE_IN_FRAGMENT"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "Unknown Code '230043' in the CodeSystem 'https://fhir.nwgenomics.nhs.uk/CodeSystem/MFTQuestionIds' version '0.1.0' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"
            },
            "expression": [
              "Questionnaire/GenomicOrderEntryOptionalQuestions: Questionnaire.item[2].item[5].item[1].code[1].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 108035
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "UNKNOWN_CODE_IN_FRAGMENT"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "Unknown Code '230048' in the CodeSystem 'https://fhir.nwgenomics.nhs.uk/CodeSystem/MFTQuestionIds' version '0.1.0' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"
            },
            "expression": [
              "Questionnaire/GenomicOrderEntryOptionalQuestions: Questionnaire.item[2].item[5].item[2].code[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 108253
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "UNKNOWN_CODE_IN_FRAGMENT"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "Unknown Code '230057' in the CodeSystem 'https://fhir.nwgenomics.nhs.uk/CodeSystem/MFTQuestionIds' version '0.1.0' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"
            },
            "expression": [
              "Questionnaire/GenomicOrderEntryOptionalQuestions: Questionnaire.item[2].item[5].item[3].code[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 108460
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "UNKNOWN_CODE_IN_FRAGMENT"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "Unknown Code '230035' in the CodeSystem 'https://fhir.nwgenomics.nhs.uk/CodeSystem/MFTQuestionIds' version '0.1.0' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"
            },
            "expression": [
              "Questionnaire/GenomicOrderEntryOptionalQuestions: Questionnaire.item[2].item[6].code[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 108751
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "UNKNOWN_CODE_IN_FRAGMENT"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "Unknown Code '230036' in the CodeSystem 'https://fhir.nwgenomics.nhs.uk/CodeSystem/MFTQuestionIds' version '0.1.0' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"
            },
            "expression": [
              "Questionnaire/GenomicOrderEntryOptionalQuestions: Questionnaire.item[2].item[7].code[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 108960
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "UNKNOWN_CODE_IN_FRAGMENT"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "Unknown Code '230038' in the CodeSystem 'https://fhir.nwgenomics.nhs.uk/CodeSystem/MFTQuestionIds' version '0.1.0' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"
            },
            "expression": [
              "Questionnaire/GenomicOrderEntryOptionalQuestions: Questionnaire.item[2].item[8].code[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 109218
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "UNKNOWN_CODE_IN_FRAGMENT"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "Unknown Code '230045' in the CodeSystem 'https://fhir.nwgenomics.nhs.uk/CodeSystem/MFTQuestionIds' version '0.1.0' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"
            },
            "expression": [
              "Questionnaire/GenomicOrderEntryOptionalQuestions: Questionnaire.item[2].item[9].code[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 109419
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "UNKNOWN_CODE_IN_FRAGMENT"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "Unknown Code '230059' in the CodeSystem 'https://fhir.nwgenomics.nhs.uk/CodeSystem/MFTQuestionIds' version '0.1.0' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"
            },
            "expression": [
              "Questionnaire/GenomicOrderEntryOptionalQuestions: Questionnaire.item[2].item[10].code[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 109600
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "UNKNOWN_CODE_IN_FRAGMENT"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "Unknown Code '230060' in the CodeSystem 'https://fhir.nwgenomics.nhs.uk/CodeSystem/MFTQuestionIds' version '0.1.0' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"
            },
            "expression": [
              "Questionnaire/GenomicOrderEntryOptionalQuestions: Questionnaire.item[2].item[11].code[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 109919
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "UNKNOWN_CODE_IN_FRAGMENT"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "Unknown Code '230061' in the CodeSystem 'https://fhir.nwgenomics.nhs.uk/CodeSystem/MFTQuestionIds' version '0.1.0' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"
            },
            "expression": [
              "Questionnaire/GenomicOrderEntryOptionalQuestions: Questionnaire.item[2].item[12].code[1].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 110243
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "UNKNOWN_CODE_IN_FRAGMENT"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "Unknown Code '230062' in the CodeSystem 'https://fhir.nwgenomics.nhs.uk/CodeSystem/MFTQuestionIds' version '0.1.0' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"
            },
            "expression": [
              "Questionnaire/GenomicOrderEntryOptionalQuestions: Questionnaire.item[2].item[13].code[1].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 110528
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "UNKNOWN_CODE_IN_FRAGMENT"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "Unknown Code '230064' in the CodeSystem 'https://fhir.nwgenomics.nhs.uk/CodeSystem/MFTQuestionIds' version '0.1.0' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"
            },
            "expression": [
              "Questionnaire/GenomicOrderEntryOptionalQuestions: Questionnaire.item[2].item[14].code[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 110812
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "UNKNOWN_CODE_IN_FRAGMENT"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "Unknown Code '230065' in the CodeSystem 'https://fhir.nwgenomics.nhs.uk/CodeSystem/MFTQuestionIds' version '0.1.0' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"
            },
            "expression": [
              "Questionnaire/GenomicOrderEntryOptionalQuestions: Questionnaire.item[2].item[15].code[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 111046
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "UNKNOWN_CODE_IN_FRAGMENT"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "Unknown Code '230066' in the CodeSystem 'https://fhir.nwgenomics.nhs.uk/CodeSystem/MFTQuestionIds' version '0.1.0' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"
            },
            "expression": [
              "Questionnaire/GenomicOrderEntryOptionalQuestions: Questionnaire.item[2].item[16].code[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 111348
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "UNKNOWN_CODE_IN_FRAGMENT"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "Unknown Code '230067' in the CodeSystem 'https://fhir.nwgenomics.nhs.uk/CodeSystem/MFTQuestionIds' version '0.1.0' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"
            },
            "expression": [
              "Questionnaire/GenomicOrderEntryOptionalQuestions: Questionnaire.item[2].item[17].code[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 111666
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "UNKNOWN_CODE_IN_FRAGMENT"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "Unknown Code '230068' in the CodeSystem 'https://fhir.nwgenomics.nhs.uk/CodeSystem/MFTQuestionIds' version '0.1.0' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"
            },
            "expression": [
              "Questionnaire/GenomicOrderEntryOptionalQuestions: Questionnaire.item[2].item[18].code[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 111911
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "UNKNOWN_CODE_IN_FRAGMENT"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "Unknown Code '230100' in the CodeSystem 'https://fhir.nwgenomics.nhs.uk/CodeSystem/MFTQuestionIds' version '0.1.0' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"
            },
            "expression": [
              "Questionnaire/GenomicOrderEntryOptionalQuestions: Questionnaire.item[2].item[19].code[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 112156
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/Questionnaire#que-2"
              }
            ],
            "severity": "error",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: que-2: 'The link ids for groups and questions must be unique within the questionnaire (descendants().linkId.isDistinct())' (defined in http://hl7.org/fhir/StructureDefinition/Questionnaire)"
            },
            "expression": [
              "Questionnaire/GenomicOrderEntryOptionalQuestions: Questionnaire"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/Questionnaire-GenomicTestOrder",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Questionnaire-GenomicTestOrder",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 168240
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Unknown_Code_in_Version"
              }
            ],
            "severity": "error",
            "code": "code-invalid",
            "details": {
              "text": "Unknown code '598151000005105' in the CodeSystem 'http://snomed.info/sct' version 'http://snomed.info/sct/83821000000107/version/20230412' (UK Edition)"
            },
            "expression": [
              "Questionnaire/GenomicTestOrder: Questionnaire.item[4].item[2].item[0].item[2].code[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 169432
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/Questionnaire#que-1"
              }
            ],
            "severity": "error",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: que-1: 'Group items must have nested items, display items cannot have nested items ((type='group' implies item.empty().not()) and (type.trace('type')='display' implies item.trace('item').empty()))' (defined in http://hl7.org/fhir/StructureDefinition/Questionnaire)"
            },
            "expression": [
              "Questionnaire/GenomicTestOrder: Questionnaire.item[5]"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/Questionnaire-GenomicTestOrderFuture",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Questionnaire-GenomicTestOrderFuture",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 185192
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://snowstorm.ihtsdotools.org/fhir'"
            },
            "expression": [
              "Questionnaire/GenomicTestOrderFuture: Questionnaire.item[4].item[4].extension[1].value.ofType(url)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 185640
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TYPE_SPECIFIC_CHECKS_DT_CANONICAL_RESOLVE"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "A definition could not be found for Canonical URL 'http://snomed.info/sct/900000000000207008?fhir_vs=ecl/<782964007'"
            },
            "expression": [
              "Questionnaire/GenomicTestOrderFuture: Questionnaire.item[4].item[4].answerValueSet"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 186976
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://snowstorm.ihtsdotools.org/fhir'"
            },
            "expression": [
              "Questionnaire/GenomicTestOrderFuture: Questionnaire.item[4].item[6].item[0].extension[1].value.ofType(url)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 187332
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TYPE_SPECIFIC_CHECKS_DT_CANONICAL_RESOLVE"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "A definition could not be found for Canonical URL 'http://snomed.info/sct/900000000000207008?fhir_vs=ecl/<737294004'"
            },
            "expression": [
              "Questionnaire/GenomicTestOrderFuture: Questionnaire.item[4].item[6].item[0].answerValueSet"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 187477
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://snowstorm.ihtsdotools.org/fhir'"
            },
            "expression": [
              "Questionnaire/GenomicTestOrderFuture: Questionnaire.item[4].item[7].extension[0].value.ofType(url)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 187734
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TYPE_SPECIFIC_CHECKS_DT_CANONICAL_RESOLVE"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "A definition could not be found for Canonical URL 'http://snomed.info/sct/900000000000207008?fhir_vs=ecl/<1222594003'"
            },
            "expression": [
              "Questionnaire/GenomicTestOrderFuture: Questionnaire.item[4].item[7].answerValueSet"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 190763
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Unknown_Code_in_Version"
              }
            ],
            "severity": "error",
            "code": "code-invalid",
            "details": {
              "text": "Unknown code '598151000005105' in the CodeSystem 'http://snomed.info/sct' version 'http://snomed.info/sct/83821000000107/version/20230412' (UK Edition)"
            },
            "expression": [
              "Questionnaire/GenomicTestOrderFuture: Questionnaire.item[4].item[9].item[0].item[2].code[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 193921
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "UNKNOWN_CODE_IN_FRAGMENT"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "Unknown Code '230033' in the CodeSystem 'https://fhir.nwgenomics.nhs.uk/CodeSystem/MFTQuestionIds' version '0.1.0' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"
            },
            "expression": [
              "Questionnaire/GenomicTestOrderFuture: Questionnaire.item[5].item[2].item[2].code[0].code"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/Questionnaire-GenomicTestReport",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Questionnaire-GenomicTestReport",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "Publisher"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "URL Mismatch https://fhir.nwgenomics.nhs.uk/Questionnaire/GenomicTestReport vs https://fhir.nwgenomics.nhs.uk/Questionnaire/81247-9"
            },
            "expression": [
              "/scratch/repo/fsh-generated/resources/Questionnaire-GenomicTestReport"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/RelatedPerson-RelatedPerson-Birmingham-Lancaster",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "RelatedPerson-RelatedPerson-Birmingham-Lancaster",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 34
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 6
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Display_Name_for__should_be_one_of__instead_of"
              }
            ],
            "severity": "error",
            "code": "invalid",
            "details": {
              "text": "Wrong Display Name 'daughter' for http://terminology.hl7.org/CodeSystem/v3-RoleCode#DAU. Valid display is 'natural daughter' (en) (for the language(s) 'en-GB')"
            },
            "expression": [
              "RelatedPerson/RelatedPerson-Birmingham-Lancaster: RelatedPerson.relationship[0].coding[0].display"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/RelatedPerson-RelatedPerson-Birmingham-London",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "RelatedPerson-RelatedPerson-Birmingham-London",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 34
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 6
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Display_Name_for__should_be_one_of__instead_of"
              }
            ],
            "severity": "error",
            "code": "invalid",
            "details": {
              "text": "Wrong Display Name 'son' for http://terminology.hl7.org/CodeSystem/v3-RoleCode#SON. Valid display is 'natural son' (en) (for the language(s) 'en-GB')"
            },
            "expression": [
              "RelatedPerson/RelatedPerson-Birmingham-London: RelatedPerson.relationship[0].coding[0].display"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/RelatedPerson-RelatedPerson-Lancaster-London",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "RelatedPerson-RelatedPerson-Lancaster-London"
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/RelatedPerson-RelatedPerson-London-Lancaster",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "RelatedPerson-RelatedPerson-London-Lancaster"
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/RelatedPerson-RelatedPerson-Wrexham-Lancaster",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "RelatedPerson-RelatedPerson-Wrexham-Lancaster",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 34
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 6
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Display_Name_for__should_be_one_of__instead_of"
              }
            ],
            "severity": "error",
            "code": "invalid",
            "details": {
              "text": "Wrong Display Name 'daughter' for http://terminology.hl7.org/CodeSystem/v3-RoleCode#DAU. Valid display is 'natural daughter' (en) (for the language(s) 'en-GB')"
            },
            "expression": [
              "RelatedPerson/RelatedPerson-Wrexham-Lancaster: RelatedPerson.relationship[0].coding[0].display"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/RelatedPerson-RelatedPerson-Wrexham-London",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "RelatedPerson-RelatedPerson-Wrexham-London",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 34
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 6
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Display_Name_for__should_be_one_of__instead_of"
              }
            ],
            "severity": "error",
            "code": "invalid",
            "details": {
              "text": "Wrong Display Name 'daughter' for http://terminology.hl7.org/CodeSystem/v3-RoleCode#DAU. Valid display is 'natural daughter' (en) (for the language(s) 'en-GB')"
            },
            "expression": [
              "RelatedPerson/RelatedPerson-Wrexham-London: RelatedPerson.relationship[0].coding[0].display"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/SearchParameter-assigner",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "SearchParameter-assigner",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 2131
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/SearchParameter#spd-0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: spd-0: 'Name should be usable as an identifier for the module by machine processing applications such as code generation (name.matches('[A-Z]([A-Za-z0-9_]){0,254}'))'"
            },
            "expression": [
              "SearchParameter/assigner: SearchParameter"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/ServiceRequest-ServiceRequestGenomicsOrderAttachment",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ServiceRequest-ServiceRequestGenomicsOrderAttachment",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 19
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 6
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "SLICING_CANNOT_BE_EVALUATED"
              }
            ],
            "severity": "error",
            "code": "processing",
            "details": {
              "text": "Slicing cannot be evaluated: Could not match discriminator (type) for slice ServiceRequest.identifier:OrderFillerNumber in profile https://fhir.nwgenomics.nhs.uk/StructureDefinition/ServiceRequest|0.1.0 - the discriminator [type] does not have fixed value, binding or existence assertions"
            },
            "expression": [
              "ServiceRequest/ServiceRequestGenomicsOrderAttachment: ServiceRequest.identifier[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 37
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 6
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "SLICING_CANNOT_BE_EVALUATED"
              }
            ],
            "severity": "error",
            "code": "processing",
            "details": {
              "text": "Slicing cannot be evaluated: Could not match discriminator (type) for slice ServiceRequest.identifier:OrderFillerNumber in profile https://fhir.nwgenomics.nhs.uk/StructureDefinition/ServiceRequest|0.1.0 - the discriminator [type] does not have fixed value, binding or existence assertions"
            },
            "expression": [
              "ServiceRequest/ServiceRequestGenomicsOrderAttachment: ServiceRequest.identifier[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 35
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 61
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'urn:oid:1.2.840.114350.1.13.0.1.7.2.798268'"
            },
            "expression": [
              "ServiceRequest/ServiceRequestGenomicsOrderAttachment: ServiceRequest.identifier[0].system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/ServiceRequest-ServiceRequestGenomicsOrderCodedEntries",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ServiceRequest-ServiceRequestGenomicsOrderCodedEntries",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 19
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 6
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "SLICING_CANNOT_BE_EVALUATED"
              }
            ],
            "severity": "error",
            "code": "processing",
            "details": {
              "text": "Slicing cannot be evaluated: Could not match discriminator (type) for slice ServiceRequest.identifier:OrderFillerNumber in profile https://fhir.nwgenomics.nhs.uk/StructureDefinition/ServiceRequest|0.1.0 - the discriminator [type] does not have fixed value, binding or existence assertions"
            },
            "expression": [
              "ServiceRequest/ServiceRequestGenomicsOrderCodedEntries: ServiceRequest.identifier[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 37
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 6
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "SLICING_CANNOT_BE_EVALUATED"
              }
            ],
            "severity": "error",
            "code": "processing",
            "details": {
              "text": "Slicing cannot be evaluated: Could not match discriminator (type) for slice ServiceRequest.identifier:OrderFillerNumber in profile https://fhir.nwgenomics.nhs.uk/StructureDefinition/ServiceRequest|0.1.0 - the discriminator [type] does not have fixed value, binding or existence assertions"
            },
            "expression": [
              "ServiceRequest/ServiceRequestGenomicsOrderCodedEntries: ServiceRequest.identifier[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 35
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 61
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'urn:oid:1.2.840.114350.1.13.0.1.7.2.798268'"
            },
            "expression": [
              "ServiceRequest/ServiceRequestGenomicsOrderCodedEntries: ServiceRequest.identifier[0].system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/Specimen-SpecimenExample",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Specimen-SpecimenExample"
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/StructureDefinition-AuditEvent",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "StructureDefinition-AuditEvent",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 130489
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TYPE_SPECIFIC_CHECKS_DT_CANONICAL_MULTIPLE_POSSIBLE_VERSIONS"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "There are multiple different potential matches for the url 'http://terminology.hl7.org/ValueSet/v3-PurposeOfUse'. It might be a good idea to fix to the correct version to reduce the likelihood of a wrong version being selected by an implementation/implementer, or use the [IG Parameter `pin-canonicals`](https://hl7.org/fhir/tools/CodeSystem-ig-parameters.html). Using version '3.1.0', found versions: 2.0.0 (from hl7.terminology.r4#5.0.0), 3.1.0 (from hl7.terminology.r4#7.0.1). Suggested fix: change the canonical reference from 'http://terminology.hl7.org/ValueSet/v3-PurposeOfUse' to 'http://terminology.hl7.org/ValueSet/v3-PurposeOfUse|3.1.0'"
            },
            "expression": [
              "StructureDefinition/AuditEvent: StructureDefinition.snapshot.element[16].binding.valueSet"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 157771
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TYPE_SPECIFIC_CHECKS_DT_CANONICAL_MULTIPLE_POSSIBLE_VERSIONS"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "There are multiple different potential matches for the url 'http://terminology.hl7.org/ValueSet/v3-PurposeOfUse'. It might be a good idea to fix to the correct version to reduce the likelihood of a wrong version being selected by an implementation/implementer, or use the [IG Parameter `pin-canonicals`](https://hl7.org/fhir/tools/CodeSystem-ig-parameters.html). Using version '3.1.0', found versions: 2.0.0 (from hl7.terminology.r4#5.0.0), 3.1.0 (from hl7.terminology.r4#7.0.1). Suggested fix: change the canonical reference from 'http://terminology.hl7.org/ValueSet/v3-PurposeOfUse' to 'http://terminology.hl7.org/ValueSet/v3-PurposeOfUse|3.1.0'"
            },
            "expression": [
              "StructureDefinition/AuditEvent: StructureDefinition.snapshot.element[36].binding.valueSet"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 185147
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TYPE_SPECIFIC_CHECKS_DT_CANONICAL_MULTIPLE_POSSIBLE_VERSIONS"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "There are multiple different potential matches for the url 'http://terminology.hl7.org/ValueSet/v3-PurposeOfUse'. It might be a good idea to fix to the correct version to reduce the likelihood of a wrong version being selected by an implementation/implementer, or use the [IG Parameter `pin-canonicals`](https://hl7.org/fhir/tools/CodeSystem-ig-parameters.html). Using version '3.1.0', found versions: 2.0.0 (from hl7.terminology.r4#5.0.0), 3.1.0 (from hl7.terminology.r4#7.0.1). Suggested fix: change the canonical reference from 'http://terminology.hl7.org/ValueSet/v3-PurposeOfUse' to 'http://terminology.hl7.org/ValueSet/v3-PurposeOfUse|3.1.0'"
            },
            "expression": [
              "StructureDefinition/AuditEvent: StructureDefinition.snapshot.element[56].binding.valueSet"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 221934
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TYPE_SPECIFIC_CHECKS_DT_CANONICAL_MULTIPLE_POSSIBLE_VERSIONS"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "There are multiple different potential matches for the url 'http://terminology.hl7.org/ValueSet/v3-PurposeOfUse'. It might be a good idea to fix to the correct version to reduce the likelihood of a wrong version being selected by an implementation/implementer, or use the [IG Parameter `pin-canonicals`](https://hl7.org/fhir/tools/CodeSystem-ig-parameters.html). Using version '3.1.0', found versions: 2.0.0 (from hl7.terminology.r4#5.0.0), 3.1.0 (from hl7.terminology.r4#7.0.1). Suggested fix: change the canonical reference from 'http://terminology.hl7.org/ValueSet/v3-PurposeOfUse' to 'http://terminology.hl7.org/ValueSet/v3-PurposeOfUse|3.1.0'"
            },
            "expression": [
              "StructureDefinition/AuditEvent: StructureDefinition.snapshot.element[82].binding.valueSet"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 258754
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TYPE_SPECIFIC_CHECKS_DT_CANONICAL_MULTIPLE_POSSIBLE_VERSIONS"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "There are multiple different potential matches for the url 'http://terminology.hl7.org/ValueSet/v3-PurposeOfUse'. It might be a good idea to fix to the correct version to reduce the likelihood of a wrong version being selected by an implementation/implementer, or use the [IG Parameter `pin-canonicals`](https://hl7.org/fhir/tools/CodeSystem-ig-parameters.html). Using version '3.1.0', found versions: 2.0.0 (from hl7.terminology.r4#5.0.0), 3.1.0 (from hl7.terminology.r4#7.0.1). Suggested fix: change the canonical reference from 'http://terminology.hl7.org/ValueSet/v3-PurposeOfUse' to 'http://terminology.hl7.org/ValueSet/v3-PurposeOfUse|3.1.0'"
            },
            "expression": [
              "StructureDefinition/AuditEvent: StructureDefinition.snapshot.element[108].binding.valueSet"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 295574
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TYPE_SPECIFIC_CHECKS_DT_CANONICAL_MULTIPLE_POSSIBLE_VERSIONS"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "There are multiple different potential matches for the url 'http://terminology.hl7.org/ValueSet/v3-PurposeOfUse'. It might be a good idea to fix to the correct version to reduce the likelihood of a wrong version being selected by an implementation/implementer, or use the [IG Parameter `pin-canonicals`](https://hl7.org/fhir/tools/CodeSystem-ig-parameters.html). Using version '3.1.0', found versions: 2.0.0 (from hl7.terminology.r4#5.0.0), 3.1.0 (from hl7.terminology.r4#7.0.1). Suggested fix: change the canonical reference from 'http://terminology.hl7.org/ValueSet/v3-PurposeOfUse' to 'http://terminology.hl7.org/ValueSet/v3-PurposeOfUse|3.1.0'"
            },
            "expression": [
              "StructureDefinition/AuditEvent: StructureDefinition.snapshot.element[134].binding.valueSet"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 439354
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "The slice 'user' on path 'AuditEvent.agent' is not marked as 'must-support' which is not consistent with the element that defines the slicing, where 'must-support' is true"
            },
            "expression": [
              "StructureDefinition/AuditEvent: StructureDefinition.snapshot"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 439354
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "The slice 'server' on path 'AuditEvent.agent' is not marked as 'must-support' which is not consistent with the element that defines the slicing, where 'must-support' is true"
            },
            "expression": [
              "StructureDefinition/AuditEvent: StructureDefinition.snapshot"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 439354
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "The slice 'client' on path 'AuditEvent.agent' is not marked as 'must-support' which is not consistent with the element that defines the slicing, where 'must-support' is true"
            },
            "expression": [
              "StructureDefinition/AuditEvent: StructureDefinition.snapshot"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "Publisher"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The Implementation Guide contains no examples for this profile"
            },
            "expression": [
              "StructureDefinition.where(url = 'https://fhir.nwgenomics.nhs.uk/StructureDefinition/AuditEvent')"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/StructureDefinition-Binary",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "StructureDefinition-Binary"
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/StructureDefinition-CodeableReference",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "StructureDefinition-CodeableReference"
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/StructureDefinition-Composition-GenomicReport",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "StructureDefinition-Composition-GenomicReport",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 307314
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TYPE_SPECIFIC_CHECKS_DT_CANONICAL_MULTIPLE_POSSIBLE_VERSIONS"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "There are multiple different potential matches for the url 'http://terminology.hl7.org/ValueSet/v3-ActCode'. It might be a good idea to fix to the correct version to reduce the likelihood of a wrong version being selected by an implementation/implementer, or use the [IG Parameter `pin-canonicals`](https://hl7.org/fhir/tools/CodeSystem-ig-parameters.html). Using version '3.0.0', found versions: 2.0.0 (from hl7.terminology.r4#5.0.0), 3.0.0 (from hl7.terminology.r4#7.0.1). Suggested fix: change the canonical reference from 'http://terminology.hl7.org/ValueSet/v3-ActCode' to 'http://terminology.hl7.org/ValueSet/v3-ActCode|3.0.0'"
            },
            "expression": [
              "StructureDefinition/Composition-GenomicReport: StructureDefinition.snapshot.element[87].binding.valueSet"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 486534
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Display_Name_for__should_be_one_of__instead_of"
              }
            ],
            "severity": "error",
            "code": "invalid",
            "details": {
              "text": "Wrong Display Name 'Procedure findings' for http://loinc.org#59776-5. Valid display is one of 3 choices: 'Procedure findings Narrative' (en-US), 'Procedure findings Narrative' (en-US) or 'Findings' (en-US) (for the language(s) 'en-GB')"
            },
            "expression": [
              "StructureDefinition/Composition-GenomicReport: StructureDefinition.snapshot.element[220].pattern.ofType(CodeableConcept).coding[0].display"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 520701
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Display_Name_for__should_be_one_of__instead_of"
              }
            ],
            "severity": "error",
            "code": "invalid",
            "details": {
              "text": "Wrong Display Name 'Procedure indications' for http://loinc.org#59768-2. Valid display is one of 3 choices: 'Procedure indications [Interpretation] Narrative' (en-US), 'Procedure indications [Interpretation] Narrative' (en-US) or 'Procedure indications Imp' (en-US) (for the language(s) 'en-GB')"
            },
            "expression": [
              "StructureDefinition/Composition-GenomicReport: StructureDefinition.snapshot.element[245].pattern.ofType(CodeableConcept).coding[0].display"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 588080
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Display_Name_for__should_be_one_of__instead_of"
              }
            ],
            "severity": "error",
            "code": "invalid",
            "details": {
              "text": "Wrong Display Name 'Procedure findings' for http://loinc.org#59776-5. Valid display is one of 3 choices: 'Procedure findings Narrative' (en-US), 'Procedure findings Narrative' (en-US) or 'Findings' (en-US) (for the language(s) 'en-GB')"
            },
            "expression": [
              "StructureDefinition/Composition-GenomicReport: StructureDefinition.differential.element[45].pattern.ofType(CodeableConcept).coding[0].display"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 589019
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Display_Name_for__should_be_one_of__instead_of"
              }
            ],
            "severity": "error",
            "code": "invalid",
            "details": {
              "text": "Wrong Display Name 'Procedure indications' for http://loinc.org#59768-2. Valid display is one of 3 choices: 'Procedure indications [Interpretation] Narrative' (en-US), 'Procedure indications [Interpretation] Narrative' (en-US) or 'Procedure indications Imp' (en-US) (for the language(s) 'en-GB')"
            },
            "expression": [
              "StructureDefinition/Composition-GenomicReport: StructureDefinition.differential.element[49].pattern.ofType(CodeableConcept).coding[0].display"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "Publisher"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The Implementation Guide contains no examples for this profile"
            },
            "expression": [
              "StructureDefinition.where(url = 'https://fhir.nwgenomics.nhs.uk/StructureDefinition/Composition-GenomicReport')"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/StructureDefinition-Composition",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "StructureDefinition-Composition",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 64325
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TYPE_SPECIFIC_CHECKS_DT_CANONICAL_MULTIPLE_POSSIBLE_VERSIONS"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "There are multiple different potential matches for the url 'http://terminology.hl7.org/ValueSet/v3-ActCode'. It might be a good idea to fix to the correct version to reduce the likelihood of a wrong version being selected by an implementation/implementer, or use the [IG Parameter `pin-canonicals`](https://hl7.org/fhir/tools/CodeSystem-ig-parameters.html). Using version '3.0.0', found versions: 2.0.0 (from hl7.terminology.r4#5.0.0), 3.0.0 (from hl7.terminology.r4#7.0.1). Suggested fix: change the canonical reference from 'http://terminology.hl7.org/ValueSet/v3-ActCode' to 'http://terminology.hl7.org/ValueSet/v3-ActCode|3.0.0'"
            },
            "expression": [
              "StructureDefinition/Composition: StructureDefinition.snapshot.element[37].binding.valueSet"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/StructureDefinition-Condition",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "StructureDefinition-Condition",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 12627
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TERMINOLOGY_TX_SYSTEM_NO_CODE"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "A code with no system has no defined meaning, and it cannot be validated. A system should be provided"
            },
            "expression": [
              "StructureDefinition/Condition: StructureDefinition.keyword[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 12675
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TERMINOLOGY_TX_SYSTEM_NO_CODE"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "A code with no system has no defined meaning, and it cannot be validated. A system should be provided"
            },
            "expression": [
              "StructureDefinition/Condition: StructureDefinition.keyword[1]"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/StructureDefinition-CorrelationIdentifier",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "StructureDefinition-CorrelationIdentifier"
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/StructureDefinition-DiagnosticReport",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "StructureDefinition-DiagnosticReport",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 148914
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TERMINOLOGY_TX_SYSTEM_NO_CODE"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "A code with no system has no defined meaning, and it cannot be validated. A system should be provided"
            },
            "expression": [
              "StructureDefinition/DiagnosticReport: StructureDefinition.keyword[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 148961
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TERMINOLOGY_TX_SYSTEM_NO_CODE"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "A code with no system has no defined meaning, and it cannot be validated. A system should be provided"
            },
            "expression": [
              "StructureDefinition/DiagnosticReport: StructureDefinition.keyword[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 149002
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TERMINOLOGY_TX_SYSTEM_NO_CODE"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "A code with no system has no defined meaning, and it cannot be validated. A system should be provided"
            },
            "expression": [
              "StructureDefinition/DiagnosticReport: StructureDefinition.keyword[2]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 255365
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TYPE_SPECIFIC_CHECKS_DT_CANONICAL_MULTIPLE_POSSIBLE_VERSIONS"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "There are multiple different potential matches for the url 'http://hl7.org/fhir/StructureDefinition/event-performerFunction'. It might be a good idea to fix to the correct version to reduce the likelihood of a wrong version being selected by an implementation/implementer, or use the [IG Parameter `pin-canonicals`](https://hl7.org/fhir/tools/CodeSystem-ig-parameters.html). Using version '5.2.0', found versions: 4.0.1 (from hl7.fhir.r4.core#4.0.1), 5.1.0 (from hl7.fhir.uv.extensions.r4#5.1.0), 5.2.0 (from hl7.fhir.uv.extensions.r4#5.2.0). Suggested fix: change the canonical reference from 'http://hl7.org/fhir/StructureDefinition/event-performerFunction' to 'http://hl7.org/fhir/StructureDefinition/event-performerFunction|5.2.0'"
            },
            "expression": [
              "StructureDefinition/DiagnosticReport: StructureDefinition.snapshot.element[68].type[0].profile[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 278025
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TYPE_SPECIFIC_CHECKS_DT_CANONICAL_MULTIPLE_POSSIBLE_VERSIONS"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "There are multiple different potential matches for the url 'http://hl7.org/fhir/StructureDefinition/event-performerFunction'. It might be a good idea to fix to the correct version to reduce the likelihood of a wrong version being selected by an implementation/implementer, or use the [IG Parameter `pin-canonicals`](https://hl7.org/fhir/tools/CodeSystem-ig-parameters.html). Using version '5.2.0', found versions: 4.0.1 (from hl7.fhir.r4.core#4.0.1), 5.1.0 (from hl7.fhir.uv.extensions.r4#5.1.0), 5.2.0 (from hl7.fhir.uv.extensions.r4#5.2.0). Suggested fix: change the canonical reference from 'http://hl7.org/fhir/StructureDefinition/event-performerFunction' to 'http://hl7.org/fhir/StructureDefinition/event-performerFunction|5.2.0'"
            },
            "expression": [
              "StructureDefinition/DiagnosticReport: StructureDefinition.snapshot.element[84].type[0].profile[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 300989
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TYPE_SPECIFIC_CHECKS_DT_CANONICAL_MULTIPLE_POSSIBLE_VERSIONS"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "There are multiple different potential matches for the url 'http://hl7.org/fhir/StructureDefinition/event-performerFunction'. It might be a good idea to fix to the correct version to reduce the likelihood of a wrong version being selected by an implementation/implementer, or use the [IG Parameter `pin-canonicals`](https://hl7.org/fhir/tools/CodeSystem-ig-parameters.html). Using version '5.2.0', found versions: 4.0.1 (from hl7.fhir.r4.core#4.0.1), 5.1.0 (from hl7.fhir.uv.extensions.r4#5.1.0), 5.2.0 (from hl7.fhir.uv.extensions.r4#5.2.0). Suggested fix: change the canonical reference from 'http://hl7.org/fhir/StructureDefinition/event-performerFunction' to 'http://hl7.org/fhir/StructureDefinition/event-performerFunction|5.2.0'"
            },
            "expression": [
              "StructureDefinition/DiagnosticReport: StructureDefinition.snapshot.element[100].type[0].profile[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 415376
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TYPE_SPECIFIC_CHECKS_DT_CANONICAL_MULTIPLE_POSSIBLE_VERSIONS"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "There are multiple different potential matches for the url 'http://hl7.org/fhir/StructureDefinition/event-performerFunction'. It might be a good idea to fix to the correct version to reduce the likelihood of a wrong version being selected by an implementation/implementer, or use the [IG Parameter `pin-canonicals`](https://hl7.org/fhir/tools/CodeSystem-ig-parameters.html). Using version '5.2.0', found versions: 4.0.1 (from hl7.fhir.r4.core#4.0.1), 5.1.0 (from hl7.fhir.uv.extensions.r4#5.1.0), 5.2.0 (from hl7.fhir.uv.extensions.r4#5.2.0). Suggested fix: change the canonical reference from 'http://hl7.org/fhir/StructureDefinition/event-performerFunction' to 'http://hl7.org/fhir/StructureDefinition/event-performerFunction|5.2.0'"
            },
            "expression": [
              "StructureDefinition/DiagnosticReport: StructureDefinition.differential.element[25].type[0].profile[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 416209
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TYPE_SPECIFIC_CHECKS_DT_CANONICAL_MULTIPLE_POSSIBLE_VERSIONS"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "There are multiple different potential matches for the url 'http://hl7.org/fhir/StructureDefinition/event-performerFunction'. It might be a good idea to fix to the correct version to reduce the likelihood of a wrong version being selected by an implementation/implementer, or use the [IG Parameter `pin-canonicals`](https://hl7.org/fhir/tools/CodeSystem-ig-parameters.html). Using version '5.2.0', found versions: 4.0.1 (from hl7.fhir.r4.core#4.0.1), 5.1.0 (from hl7.fhir.uv.extensions.r4#5.1.0), 5.2.0 (from hl7.fhir.uv.extensions.r4#5.2.0). Suggested fix: change the canonical reference from 'http://hl7.org/fhir/StructureDefinition/event-performerFunction' to 'http://hl7.org/fhir/StructureDefinition/event-performerFunction|5.2.0'"
            },
            "expression": [
              "StructureDefinition/DiagnosticReport: StructureDefinition.differential.element[31].type[0].profile[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 416951
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TYPE_SPECIFIC_CHECKS_DT_CANONICAL_MULTIPLE_POSSIBLE_VERSIONS"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "There are multiple different potential matches for the url 'http://hl7.org/fhir/StructureDefinition/event-performerFunction'. It might be a good idea to fix to the correct version to reduce the likelihood of a wrong version being selected by an implementation/implementer, or use the [IG Parameter `pin-canonicals`](https://hl7.org/fhir/tools/CodeSystem-ig-parameters.html). Using version '5.2.0', found versions: 4.0.1 (from hl7.fhir.r4.core#4.0.1), 5.1.0 (from hl7.fhir.uv.extensions.r4#5.1.0), 5.2.0 (from hl7.fhir.uv.extensions.r4#5.2.0). Suggested fix: change the canonical reference from 'http://hl7.org/fhir/StructureDefinition/event-performerFunction' to 'http://hl7.org/fhir/StructureDefinition/event-performerFunction|5.2.0'"
            },
            "expression": [
              "StructureDefinition/DiagnosticReport: StructureDefinition.differential.element[35].type[0].profile[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "SD_VALUE_COMPLEX_FIXED"
              }
            ],
            "severity": "warning",
            "code": "exception",
            "details": {
              "text": "For the complex type Coding, consider using a pattern rather than a fixed value to avoid over-constraining the instance"
            },
            "expression": [
              "StructureDefinition/DiagnosticReport: StructureDefinition.snapshot.element[118].fixed.ofType(Coding)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "SD_VALUE_COMPLEX_FIXED"
              }
            ],
            "severity": "warning",
            "code": "exception",
            "details": {
              "text": "For the complex type Coding, consider using a pattern rather than a fixed value to avoid over-constraining the instance"
            },
            "expression": [
              "StructureDefinition/DiagnosticReport: StructureDefinition.snapshot.element[152].fixed.ofType(Coding)"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/StructureDefinition-DiagnosticReportProcedure",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "StructureDefinition-DiagnosticReportProcedure",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "SD_CONTEXT_SHOULD_NOT_BE_ELEMENT"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "Review the extension type for DiagnosticReportProcedure: extensions should not have a context of Element unless it's really intended that they can be used anywhere"
            },
            "expression": [
              "StructureDefinition/DiagnosticReportProcedure: StructureDefinition.context[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "Publisher"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The Implementation Guide contains no examples for this extension"
            },
            "expression": [
              "StructureDefinition.where(url = 'https://fhir.nwgenomics.nhs.uk/StructureDefinition/DiagnosticReportProcedure')"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/StructureDefinition-DocumentReference",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "StructureDefinition-DocumentReference",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 169657
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TYPE_SPECIFIC_CHECKS_DT_CANONICAL_MULTIPLE_POSSIBLE_VERSIONS"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "There are multiple different potential matches for the url 'http://terminology.hl7.org/ValueSet/v3-ActCode'. It might be a good idea to fix to the correct version to reduce the likelihood of a wrong version being selected by an implementation/implementer, or use the [IG Parameter `pin-canonicals`](https://hl7.org/fhir/tools/CodeSystem-ig-parameters.html). Using version '3.0.0', found versions: 2.0.0 (from hl7.terminology.r4#5.0.0), 3.0.0 (from hl7.terminology.r4#7.0.1). Suggested fix: change the canonical reference from 'http://terminology.hl7.org/ValueSet/v3-ActCode' to 'http://terminology.hl7.org/ValueSet/v3-ActCode|3.0.0'"
            },
            "expression": [
              "StructureDefinition/DocumentReference: StructureDefinition.snapshot.element[63].binding.valueSet"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/StructureDefinition-Encounter",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "StructureDefinition-Encounter",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 38090
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TERMINOLOGY_TX_SYSTEM_NO_CODE"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "A code with no system has no defined meaning, and it cannot be validated. A system should be provided"
            },
            "expression": [
              "StructureDefinition/Encounter: StructureDefinition.keyword[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 38140
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TERMINOLOGY_TX_SYSTEM_NO_CODE"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "A code with no system has no defined meaning, and it cannot be validated. A system should be provided"
            },
            "expression": [
              "StructureDefinition/Encounter: StructureDefinition.keyword[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 80958
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TYPE_SPECIFIC_CHECKS_DT_CANONICAL_MULTIPLE_POSSIBLE_VERSIONS"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "There are multiple different potential matches for the url 'http://terminology.hl7.org/ValueSet/v3-ActEncounterCode'. It might be a good idea to fix to the correct version to reduce the likelihood of a wrong version being selected by an implementation/implementer, or use the [IG Parameter `pin-canonicals`](https://hl7.org/fhir/tools/CodeSystem-ig-parameters.html). Using version '3.0.0', found versions: 2.0.0 (from hl7.terminology.r4#5.0.0), 3.0.0 (from hl7.terminology.r4#7.0.1). Suggested fix: change the canonical reference from 'http://terminology.hl7.org/ValueSet/v3-ActEncounterCode' to 'http://terminology.hl7.org/ValueSet/v3-ActEncounterCode|3.0.0'"
            },
            "expression": [
              "StructureDefinition/Encounter: StructureDefinition.snapshot.element[29].binding.valueSet"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 87980
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TYPE_SPECIFIC_CHECKS_DT_CANONICAL_MULTIPLE_POSSIBLE_VERSIONS"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "There are multiple different potential matches for the url 'http://terminology.hl7.org/ValueSet/v3-ActEncounterCode'. It might be a good idea to fix to the correct version to reduce the likelihood of a wrong version being selected by an implementation/implementer, or use the [IG Parameter `pin-canonicals`](https://hl7.org/fhir/tools/CodeSystem-ig-parameters.html). Using version '3.0.0', found versions: 2.0.0 (from hl7.terminology.r4#5.0.0), 3.0.0 (from hl7.terminology.r4#7.0.1). Suggested fix: change the canonical reference from 'http://terminology.hl7.org/ValueSet/v3-ActEncounterCode' to 'http://terminology.hl7.org/ValueSet/v3-ActEncounterCode|3.0.0'"
            },
            "expression": [
              "StructureDefinition/Encounter: StructureDefinition.snapshot.element[34].binding.valueSet"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 91336
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TYPE_SPECIFIC_CHECKS_DT_CANONICAL_MULTIPLE_POSSIBLE_VERSIONS"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "There are multiple different potential matches for the url 'http://terminology.hl7.org/ValueSet/v3-ActPriority'. It might be a good idea to fix to the correct version to reduce the likelihood of a wrong version being selected by an implementation/implementer, or use the [IG Parameter `pin-canonicals`](https://hl7.org/fhir/tools/CodeSystem-ig-parameters.html). Using version '3.0.0', found versions: 2.0.0 (from hl7.terminology.r4#5.0.0), 3.0.0 (from hl7.terminology.r4#7.0.1). Suggested fix: change the canonical reference from 'http://terminology.hl7.org/ValueSet/v3-ActPriority' to 'http://terminology.hl7.org/ValueSet/v3-ActPriority|3.0.0'"
            },
            "expression": [
              "StructureDefinition/Encounter: StructureDefinition.snapshot.element[38].binding.valueSet"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/StructureDefinition-Event",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "StructureDefinition-Event",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "Publisher"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The Implementation Guide contains no examples for this profile"
            },
            "expression": [
              "StructureDefinition.where(url = 'https://fhir.nwgenomics.nhs.uk/StructureDefinition/Event')"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/StructureDefinition-FamilyMemberHistory",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "StructureDefinition-FamilyMemberHistory",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 7147
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TERMINOLOGY_TX_SYSTEM_NO_CODE"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "A code with no system has no defined meaning, and it cannot be validated. A system should be provided"
            },
            "expression": [
              "StructureDefinition/FamilyMemberHistory: StructureDefinition.keyword[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 7195
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TERMINOLOGY_TX_SYSTEM_NO_CODE"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "A code with no system has no defined meaning, and it cannot be validated. A system should be provided"
            },
            "expression": [
              "StructureDefinition/FamilyMemberHistory: StructureDefinition.keyword[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "SD_ED_BIND_NO_BINDABLE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The element FamilyMemberHistory.extension.extension has a binding, but no bindable types are present [Extension]"
            },
            "expression": [
              "StructureDefinition/FamilyMemberHistory: StructureDefinition.snapshot.element[12].binding"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/StructureDefinition-GenomicsPedigreeNumber",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "StructureDefinition-GenomicsPedigreeNumber",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "SD_VALUE_COMPLEX_FIXED"
              }
            ],
            "severity": "warning",
            "code": "exception",
            "details": {
              "text": "For the complex type CodeableConcept, consider using a pattern rather than a fixed value to avoid over-constraining the instance"
            },
            "expression": [
              "StructureDefinition/GenomicsPedigreeNumber: StructureDefinition.snapshot.element[4].fixed.ofType(CodeableConcept)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "Publisher"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The Implementation Guide contains no examples for this data type profile"
            },
            "expression": [
              "StructureDefinition.where(url = 'https://fhir.nwgenomics.nhs.uk/StructureDefinition/GenomicsPedigreeNumber')"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/StructureDefinition-HospitalProviderSpellIdentifier",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "StructureDefinition-HospitalProviderSpellIdentifier",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 16724
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TERMINOLOGY_TX_SYSTEM_NO_CODE"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "A code with no system has no defined meaning, and it cannot be validated. A system should be provided"
            },
            "expression": [
              "StructureDefinition/HospitalProviderSpellIdentifier: StructureDefinition.keyword[0]"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/StructureDefinition-HospitalSpell",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "StructureDefinition-HospitalSpell",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 49915
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TERMINOLOGY_TX_SYSTEM_NO_CODE"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "A code with no system has no defined meaning, and it cannot be validated. A system should be provided"
            },
            "expression": [
              "StructureDefinition/HospitalSpell: StructureDefinition.keyword[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 49965
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TERMINOLOGY_TX_SYSTEM_NO_CODE"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "A code with no system has no defined meaning, and it cannot be validated. A system should be provided"
            },
            "expression": [
              "StructureDefinition/HospitalSpell: StructureDefinition.keyword[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 105170
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TYPE_SPECIFIC_CHECKS_DT_CANONICAL_MULTIPLE_POSSIBLE_VERSIONS"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "There are multiple different potential matches for the url 'http://terminology.hl7.org/ValueSet/v3-ActEncounterCode'. It might be a good idea to fix to the correct version to reduce the likelihood of a wrong version being selected by an implementation/implementer, or use the [IG Parameter `pin-canonicals`](https://hl7.org/fhir/tools/CodeSystem-ig-parameters.html). Using version '3.0.0', found versions: 2.0.0 (from hl7.terminology.r4#5.0.0), 3.0.0 (from hl7.terminology.r4#7.0.1). Suggested fix: change the canonical reference from 'http://terminology.hl7.org/ValueSet/v3-ActEncounterCode' to 'http://terminology.hl7.org/ValueSet/v3-ActEncounterCode|3.0.0'"
            },
            "expression": [
              "StructureDefinition/HospitalSpell: StructureDefinition.snapshot.element[38].binding.valueSet"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 112192
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TYPE_SPECIFIC_CHECKS_DT_CANONICAL_MULTIPLE_POSSIBLE_VERSIONS"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "There are multiple different potential matches for the url 'http://terminology.hl7.org/ValueSet/v3-ActEncounterCode'. It might be a good idea to fix to the correct version to reduce the likelihood of a wrong version being selected by an implementation/implementer, or use the [IG Parameter `pin-canonicals`](https://hl7.org/fhir/tools/CodeSystem-ig-parameters.html). Using version '3.0.0', found versions: 2.0.0 (from hl7.terminology.r4#5.0.0), 3.0.0 (from hl7.terminology.r4#7.0.1). Suggested fix: change the canonical reference from 'http://terminology.hl7.org/ValueSet/v3-ActEncounterCode' to 'http://terminology.hl7.org/ValueSet/v3-ActEncounterCode|3.0.0'"
            },
            "expression": [
              "StructureDefinition/HospitalSpell: StructureDefinition.snapshot.element[43].binding.valueSet"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 115548
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TYPE_SPECIFIC_CHECKS_DT_CANONICAL_MULTIPLE_POSSIBLE_VERSIONS"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "There are multiple different potential matches for the url 'http://terminology.hl7.org/ValueSet/v3-ActPriority'. It might be a good idea to fix to the correct version to reduce the likelihood of a wrong version being selected by an implementation/implementer, or use the [IG Parameter `pin-canonicals`](https://hl7.org/fhir/tools/CodeSystem-ig-parameters.html). Using version '3.0.0', found versions: 2.0.0 (from hl7.terminology.r4#5.0.0), 3.0.0 (from hl7.terminology.r4#7.0.1). Suggested fix: change the canonical reference from 'http://terminology.hl7.org/ValueSet/v3-ActPriority' to 'http://terminology.hl7.org/ValueSet/v3-ActPriority|3.0.0'"
            },
            "expression": [
              "StructureDefinition/HospitalSpell: StructureDefinition.snapshot.element[47].binding.valueSet"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/StructureDefinition-MedicalRecordNumber",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "StructureDefinition-MedicalRecordNumber",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "SD_VALUE_COMPLEX_FIXED"
              }
            ],
            "severity": "warning",
            "code": "exception",
            "details": {
              "text": "For the complex type CodeableConcept, consider using a pattern rather than a fixed value to avoid over-constraining the instance"
            },
            "expression": [
              "StructureDefinition/MedicalRecordNumber: StructureDefinition.snapshot.element[4].fixed.ofType(CodeableConcept)"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/StructureDefinition-MessageHeader",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "StructureDefinition-MessageHeader"
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/StructureDefinition-NHSIdentifier",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "StructureDefinition-NHSIdentifier",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 18706
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TERMINOLOGY_TX_SYSTEM_NO_CODE"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "A code with no system has no defined meaning, and it cannot be validated. A system should be provided"
            },
            "expression": [
              "StructureDefinition/NHSIdentifier: StructureDefinition.keyword[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "SD_VALUE_COMPLEX_FIXED"
              }
            ],
            "severity": "warning",
            "code": "exception",
            "details": {
              "text": "For the complex type CodeableConcept, consider using a pattern rather than a fixed value to avoid over-constraining the instance"
            },
            "expression": [
              "StructureDefinition/NHSIdentifier: StructureDefinition.snapshot.element[4].fixed.ofType(CodeableConcept)"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/StructureDefinition-NWAttachment",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "StructureDefinition-NWAttachment"
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/StructureDefinition-NWQuestionnaire",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "StructureDefinition-NWQuestionnaire",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 38725
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TYPE_SPECIFIC_CHECKS_DT_CANONICAL_MULTIPLE_POSSIBLE_VERSIONS"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "There are multiple different potential matches for the url 'http://hl7.org/fhir/StructureDefinition/designNote'. It might be a good idea to fix to the correct version to reduce the likelihood of a wrong version being selected by an implementation/implementer, or use the [IG Parameter `pin-canonicals`](https://hl7.org/fhir/tools/CodeSystem-ig-parameters.html). Using version '5.2.0', found versions: 4.0.1 (from hl7.fhir.r4.core#4.0.1), 5.1.0 (from hl7.fhir.uv.extensions.r4#5.1.0), 5.2.0 (from hl7.fhir.uv.extensions.r4#5.2.0). Suggested fix: change the canonical reference from 'http://hl7.org/fhir/StructureDefinition/designNote' to 'http://hl7.org/fhir/StructureDefinition/designNote|5.2.0'"
            },
            "expression": [
              "StructureDefinition/NWQuestionnaire: StructureDefinition.snapshot.element[8].type[0].profile[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 79005
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TYPE_SPECIFIC_CHECKS_DT_CANONICAL_MULTIPLE_POSSIBLE_VERSIONS"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "There are multiple different potential matches for the url 'http://hl7.org/fhir/StructureDefinition/designNote'. It might be a good idea to fix to the correct version to reduce the likelihood of a wrong version being selected by an implementation/implementer, or use the [IG Parameter `pin-canonicals`](https://hl7.org/fhir/tools/CodeSystem-ig-parameters.html). Using version '5.2.0', found versions: 4.0.1 (from hl7.fhir.r4.core#4.0.1), 5.1.0 (from hl7.fhir.uv.extensions.r4#5.1.0), 5.2.0 (from hl7.fhir.uv.extensions.r4#5.2.0). Suggested fix: change the canonical reference from 'http://hl7.org/fhir/StructureDefinition/designNote' to 'http://hl7.org/fhir/StructureDefinition/designNote|5.2.0'"
            },
            "expression": [
              "StructureDefinition/NWQuestionnaire: StructureDefinition.snapshot.element[37].type[0].profile[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 81981
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TYPE_SPECIFIC_CHECKS_DT_CANONICAL_MULTIPLE_POSSIBLE_VERSIONS"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "There are multiple different potential matches for the url 'http://hl7.org/fhir/StructureDefinition/questionnaire-itemControl'. It might be a good idea to fix to the correct version to reduce the likelihood of a wrong version being selected by an implementation/implementer, or use the [IG Parameter `pin-canonicals`](https://hl7.org/fhir/tools/CodeSystem-ig-parameters.html). Using version '5.2.0', found versions: 4.0.1 (from hl7.fhir.r4.core#4.0.1), 5.1.0 (from hl7.fhir.uv.extensions.r4#5.1.0), 5.2.0 (from hl7.fhir.uv.extensions.r4#5.2.0). Suggested fix: change the canonical reference from 'http://hl7.org/fhir/StructureDefinition/questionnaire-itemControl' to 'http://hl7.org/fhir/StructureDefinition/questionnaire-itemControl|5.2.0'"
            },
            "expression": [
              "StructureDefinition/NWQuestionnaire: StructureDefinition.snapshot.element[39].type[0].profile[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 84074
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TYPE_SPECIFIC_CHECKS_DT_CANONICAL_MULTIPLE_POSSIBLE_VERSIONS"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "There are multiple different potential matches for the url 'http://hl7.org/fhir/StructureDefinition/questionnaire-unitOption'. It might be a good idea to fix to the correct version to reduce the likelihood of a wrong version being selected by an implementation/implementer, or use the [IG Parameter `pin-canonicals`](https://hl7.org/fhir/tools/CodeSystem-ig-parameters.html). Using version '5.2.0', found versions: 4.0.1 (from hl7.fhir.r4.core#4.0.1), 5.1.0 (from hl7.fhir.uv.extensions.r4#5.1.0), 5.2.0 (from hl7.fhir.uv.extensions.r4#5.2.0). Suggested fix: change the canonical reference from 'http://hl7.org/fhir/StructureDefinition/questionnaire-unitOption' to 'http://hl7.org/fhir/StructureDefinition/questionnaire-unitOption|5.2.0'"
            },
            "expression": [
              "StructureDefinition/NWQuestionnaire: StructureDefinition.snapshot.element[40].type[0].profile[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 85455
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TYPE_SPECIFIC_CHECKS_DT_CANONICAL_MULTIPLE_POSSIBLE_VERSIONS"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "There are multiple different potential matches for the url 'http://hl7.org/fhir/StructureDefinition/questionnaire-unit'. It might be a good idea to fix to the correct version to reduce the likelihood of a wrong version being selected by an implementation/implementer, or use the [IG Parameter `pin-canonicals`](https://hl7.org/fhir/tools/CodeSystem-ig-parameters.html). Using version '5.2.0', found versions: 4.0.1 (from hl7.fhir.r4.core#4.0.1), 5.1.0 (from hl7.fhir.uv.extensions.r4#5.1.0), 5.2.0 (from hl7.fhir.uv.extensions.r4#5.2.0). Suggested fix: change the canonical reference from 'http://hl7.org/fhir/StructureDefinition/questionnaire-unit' to 'http://hl7.org/fhir/StructureDefinition/questionnaire-unit|5.2.0'"
            },
            "expression": [
              "StructureDefinition/NWQuestionnaire: StructureDefinition.snapshot.element[41].type[0].profile[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 86871
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TYPE_SPECIFIC_CHECKS_DT_CANONICAL_MULTIPLE_POSSIBLE_VERSIONS"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "There are multiple different potential matches for the url 'http://hl7.org/fhir/StructureDefinition/questionnaire-referenceProfile'. It might be a good idea to fix to the correct version to reduce the likelihood of a wrong version being selected by an implementation/implementer, or use the [IG Parameter `pin-canonicals`](https://hl7.org/fhir/tools/CodeSystem-ig-parameters.html). Using version '5.2.0', found versions: 4.0.1 (from hl7.fhir.r4.core#4.0.1), 5.1.0 (from hl7.fhir.uv.extensions.r4#5.1.0), 5.2.0 (from hl7.fhir.uv.extensions.r4#5.2.0). Suggested fix: change the canonical reference from 'http://hl7.org/fhir/StructureDefinition/questionnaire-referenceProfile' to 'http://hl7.org/fhir/StructureDefinition/questionnaire-referenceProfile|5.2.0'"
            },
            "expression": [
              "StructureDefinition/NWQuestionnaire: StructureDefinition.snapshot.element[42].type[0].profile[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 88324
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TYPE_SPECIFIC_CHECKS_DT_CANONICAL_MULTIPLE_POSSIBLE_VERSIONS"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "There are multiple different potential matches for the url 'http://hl7.org/fhir/StructureDefinition/questionnaire-referenceResource'. It might be a good idea to fix to the correct version to reduce the likelihood of a wrong version being selected by an implementation/implementer, or use the [IG Parameter `pin-canonicals`](https://hl7.org/fhir/tools/CodeSystem-ig-parameters.html). Using version '5.2.0', found versions: 4.0.1 (from hl7.fhir.r4.core#4.0.1), 5.1.0 (from hl7.fhir.uv.extensions.r4#5.1.0), 5.2.0 (from hl7.fhir.uv.extensions.r4#5.2.0). Suggested fix: change the canonical reference from 'http://hl7.org/fhir/StructureDefinition/questionnaire-referenceResource' to 'http://hl7.org/fhir/StructureDefinition/questionnaire-referenceResource|5.2.0'"
            },
            "expression": [
              "StructureDefinition/NWQuestionnaire: StructureDefinition.snapshot.element[43].type[0].profile[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 137418
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TYPE_SPECIFIC_CHECKS_DT_CANONICAL_MULTIPLE_POSSIBLE_VERSIONS"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "There are multiple different potential matches for the url 'http://hl7.org/fhir/StructureDefinition/questionnaire-itemControl'. It might be a good idea to fix to the correct version to reduce the likelihood of a wrong version being selected by an implementation/implementer, or use the [IG Parameter `pin-canonicals`](https://hl7.org/fhir/tools/CodeSystem-ig-parameters.html). Using version '5.2.0', found versions: 4.0.1 (from hl7.fhir.r4.core#4.0.1), 5.1.0 (from hl7.fhir.uv.extensions.r4#5.1.0), 5.2.0 (from hl7.fhir.uv.extensions.r4#5.2.0). Suggested fix: change the canonical reference from 'http://hl7.org/fhir/StructureDefinition/questionnaire-itemControl' to 'http://hl7.org/fhir/StructureDefinition/questionnaire-itemControl|5.2.0'"
            },
            "expression": [
              "StructureDefinition/NWQuestionnaire: StructureDefinition.differential.element[1].type[0].profile[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 137657
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TYPE_SPECIFIC_CHECKS_DT_CANONICAL_MULTIPLE_POSSIBLE_VERSIONS"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "There are multiple different potential matches for the url 'http://hl7.org/fhir/StructureDefinition/questionnaire-unitOption'. It might be a good idea to fix to the correct version to reduce the likelihood of a wrong version being selected by an implementation/implementer, or use the [IG Parameter `pin-canonicals`](https://hl7.org/fhir/tools/CodeSystem-ig-parameters.html). Using version '5.2.0', found versions: 4.0.1 (from hl7.fhir.r4.core#4.0.1), 5.1.0 (from hl7.fhir.uv.extensions.r4#5.1.0), 5.2.0 (from hl7.fhir.uv.extensions.r4#5.2.0). Suggested fix: change the canonical reference from 'http://hl7.org/fhir/StructureDefinition/questionnaire-unitOption' to 'http://hl7.org/fhir/StructureDefinition/questionnaire-unitOption|5.2.0'"
            },
            "expression": [
              "StructureDefinition/NWQuestionnaire: StructureDefinition.differential.element[2].type[0].profile[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 137878
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TYPE_SPECIFIC_CHECKS_DT_CANONICAL_MULTIPLE_POSSIBLE_VERSIONS"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "There are multiple different potential matches for the url 'http://hl7.org/fhir/StructureDefinition/questionnaire-unit'. It might be a good idea to fix to the correct version to reduce the likelihood of a wrong version being selected by an implementation/implementer, or use the [IG Parameter `pin-canonicals`](https://hl7.org/fhir/tools/CodeSystem-ig-parameters.html). Using version '5.2.0', found versions: 4.0.1 (from hl7.fhir.r4.core#4.0.1), 5.1.0 (from hl7.fhir.uv.extensions.r4#5.1.0), 5.2.0 (from hl7.fhir.uv.extensions.r4#5.2.0). Suggested fix: change the canonical reference from 'http://hl7.org/fhir/StructureDefinition/questionnaire-unit' to 'http://hl7.org/fhir/StructureDefinition/questionnaire-unit|5.2.0'"
            },
            "expression": [
              "StructureDefinition/NWQuestionnaire: StructureDefinition.differential.element[3].type[0].profile[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 138135
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TYPE_SPECIFIC_CHECKS_DT_CANONICAL_MULTIPLE_POSSIBLE_VERSIONS"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "There are multiple different potential matches for the url 'http://hl7.org/fhir/StructureDefinition/questionnaire-referenceProfile'. It might be a good idea to fix to the correct version to reduce the likelihood of a wrong version being selected by an implementation/implementer, or use the [IG Parameter `pin-canonicals`](https://hl7.org/fhir/tools/CodeSystem-ig-parameters.html). Using version '5.2.0', found versions: 4.0.1 (from hl7.fhir.r4.core#4.0.1), 5.1.0 (from hl7.fhir.uv.extensions.r4#5.1.0), 5.2.0 (from hl7.fhir.uv.extensions.r4#5.2.0). Suggested fix: change the canonical reference from 'http://hl7.org/fhir/StructureDefinition/questionnaire-referenceProfile' to 'http://hl7.org/fhir/StructureDefinition/questionnaire-referenceProfile|5.2.0'"
            },
            "expression": [
              "StructureDefinition/NWQuestionnaire: StructureDefinition.differential.element[4].type[0].profile[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 138395
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TYPE_SPECIFIC_CHECKS_DT_CANONICAL_MULTIPLE_POSSIBLE_VERSIONS"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "There are multiple different potential matches for the url 'http://hl7.org/fhir/StructureDefinition/questionnaire-referenceResource'. It might be a good idea to fix to the correct version to reduce the likelihood of a wrong version being selected by an implementation/implementer, or use the [IG Parameter `pin-canonicals`](https://hl7.org/fhir/tools/CodeSystem-ig-parameters.html). Using version '5.2.0', found versions: 4.0.1 (from hl7.fhir.r4.core#4.0.1), 5.1.0 (from hl7.fhir.uv.extensions.r4#5.1.0), 5.2.0 (from hl7.fhir.uv.extensions.r4#5.2.0). Suggested fix: change the canonical reference from 'http://hl7.org/fhir/StructureDefinition/questionnaire-referenceResource' to 'http://hl7.org/fhir/StructureDefinition/questionnaire-referenceResource|5.2.0'"
            },
            "expression": [
              "StructureDefinition/NWQuestionnaire: StructureDefinition.differential.element[5].type[0].profile[0]"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/StructureDefinition-Observation-DiagnosticImplication",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "StructureDefinition-Observation-DiagnosticImplication",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 37244
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TERMINOLOGY_TX_SYSTEM_NO_CODE"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "A code with no system has no defined meaning, and it cannot be validated. A system should be provided"
            },
            "expression": [
              "StructureDefinition/Observation-DiagnosticImplication: StructureDefinition.keyword[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 37285
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TERMINOLOGY_TX_SYSTEM_NO_CODE"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "A code with no system has no defined meaning, and it cannot be validated. A system should be provided"
            },
            "expression": [
              "StructureDefinition/Observation-DiagnosticImplication: StructureDefinition.keyword[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 37332
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TERMINOLOGY_TX_SYSTEM_NO_CODE"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "A code with no system has no defined meaning, and it cannot be validated. A system should be provided"
            },
            "expression": [
              "StructureDefinition/Observation-DiagnosticImplication: StructureDefinition.keyword[2]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 52139
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TYPE_SPECIFIC_CHECKS_DT_CANONICAL_MULTIPLE_POSSIBLE_VERSIONS"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "There are multiple different potential matches for the url 'http://hl7.org/fhir/StructureDefinition/observation-secondaryFinding'. It might be a good idea to fix to the correct version to reduce the likelihood of a wrong version being selected by an implementation/implementer, or use the [IG Parameter `pin-canonicals`](https://hl7.org/fhir/tools/CodeSystem-ig-parameters.html). Using version '5.2.0', found versions: 4.0.1 (from hl7.fhir.r4.core#4.0.1), 5.1.0 (from hl7.fhir.uv.extensions.r4#5.1.0), 5.2.0 (from hl7.fhir.uv.extensions.r4#5.2.0). Suggested fix: change the canonical reference from 'http://hl7.org/fhir/StructureDefinition/observation-secondaryFinding' to 'http://hl7.org/fhir/StructureDefinition/observation-secondaryFinding|5.2.0'"
            },
            "expression": [
              "StructureDefinition/Observation-DiagnosticImplication: StructureDefinition.snapshot.element[8].type[0].profile[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 53121
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TYPE_SPECIFIC_CHECKS_DT_CANONICAL_MULTIPLE_POSSIBLE_VERSIONS"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "There are multiple different potential matches for the url 'http://hl7.org/fhir/StructureDefinition/bodySite'. It might be a good idea to fix to the correct version to reduce the likelihood of a wrong version being selected by an implementation/implementer, or use the [IG Parameter `pin-canonicals`](https://hl7.org/fhir/tools/CodeSystem-ig-parameters.html). Using version '5.2.0', found versions: 4.0.1 (from hl7.fhir.r4.core#4.0.1), 5.1.0 (from hl7.fhir.uv.extensions.r4#5.1.0), 5.2.0 (from hl7.fhir.uv.extensions.r4#5.2.0). Suggested fix: change the canonical reference from 'http://hl7.org/fhir/StructureDefinition/bodySite' to 'http://hl7.org/fhir/StructureDefinition/bodySite|5.2.0'"
            },
            "expression": [
              "StructureDefinition/Observation-DiagnosticImplication: StructureDefinition.snapshot.element[9].type[0].profile[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 54403
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TYPE_SPECIFIC_CHECKS_DT_CANONICAL_MULTIPLE_POSSIBLE_VERSIONS"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "There are multiple different potential matches for the url 'http://hl7.org/fhir/StructureDefinition/workflow-relatedArtifact'. It might be a good idea to fix to the correct version to reduce the likelihood of a wrong version being selected by an implementation/implementer, or use the [IG Parameter `pin-canonicals`](https://hl7.org/fhir/tools/CodeSystem-ig-parameters.html). Using version '5.2.0', found versions: 4.0.1 (from hl7.fhir.r4.core#4.0.1), 5.1.0 (from hl7.fhir.uv.extensions.r4#5.1.0), 5.2.0 (from hl7.fhir.uv.extensions.r4#5.2.0). Suggested fix: change the canonical reference from 'http://hl7.org/fhir/StructureDefinition/workflow-relatedArtifact' to 'http://hl7.org/fhir/StructureDefinition/workflow-relatedArtifact|5.2.0'"
            },
            "expression": [
              "StructureDefinition/Observation-DiagnosticImplication: StructureDefinition.snapshot.element[10].type[0].profile[0]"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/StructureDefinition-Observation-Genotype",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "StructureDefinition-Observation-Genotype",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 27629
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TERMINOLOGY_TX_SYSTEM_NO_CODE"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "A code with no system has no defined meaning, and it cannot be validated. A system should be provided"
            },
            "expression": [
              "StructureDefinition/Observation-Genotype: StructureDefinition.keyword[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 27670
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TERMINOLOGY_TX_SYSTEM_NO_CODE"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "A code with no system has no defined meaning, and it cannot be validated. A system should be provided"
            },
            "expression": [
              "StructureDefinition/Observation-Genotype: StructureDefinition.keyword[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 27717
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TERMINOLOGY_TX_SYSTEM_NO_CODE"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "A code with no system has no defined meaning, and it cannot be validated. A system should be provided"
            },
            "expression": [
              "StructureDefinition/Observation-Genotype: StructureDefinition.keyword[2]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 42496
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TYPE_SPECIFIC_CHECKS_DT_CANONICAL_MULTIPLE_POSSIBLE_VERSIONS"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "There are multiple different potential matches for the url 'http://hl7.org/fhir/StructureDefinition/observation-secondaryFinding'. It might be a good idea to fix to the correct version to reduce the likelihood of a wrong version being selected by an implementation/implementer, or use the [IG Parameter `pin-canonicals`](https://hl7.org/fhir/tools/CodeSystem-ig-parameters.html). Using version '5.2.0', found versions: 4.0.1 (from hl7.fhir.r4.core#4.0.1), 5.1.0 (from hl7.fhir.uv.extensions.r4#5.1.0), 5.2.0 (from hl7.fhir.uv.extensions.r4#5.2.0). Suggested fix: change the canonical reference from 'http://hl7.org/fhir/StructureDefinition/observation-secondaryFinding' to 'http://hl7.org/fhir/StructureDefinition/observation-secondaryFinding|5.2.0'"
            },
            "expression": [
              "StructureDefinition/Observation-Genotype: StructureDefinition.snapshot.element[8].type[0].profile[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 43478
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TYPE_SPECIFIC_CHECKS_DT_CANONICAL_MULTIPLE_POSSIBLE_VERSIONS"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "There are multiple different potential matches for the url 'http://hl7.org/fhir/StructureDefinition/bodySite'. It might be a good idea to fix to the correct version to reduce the likelihood of a wrong version being selected by an implementation/implementer, or use the [IG Parameter `pin-canonicals`](https://hl7.org/fhir/tools/CodeSystem-ig-parameters.html). Using version '5.2.0', found versions: 4.0.1 (from hl7.fhir.r4.core#4.0.1), 5.1.0 (from hl7.fhir.uv.extensions.r4#5.1.0), 5.2.0 (from hl7.fhir.uv.extensions.r4#5.2.0). Suggested fix: change the canonical reference from 'http://hl7.org/fhir/StructureDefinition/bodySite' to 'http://hl7.org/fhir/StructureDefinition/bodySite|5.2.0'"
            },
            "expression": [
              "StructureDefinition/Observation-Genotype: StructureDefinition.snapshot.element[9].type[0].profile[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "Publisher"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The Implementation Guide contains no examples for this profile"
            },
            "expression": [
              "StructureDefinition.where(url = 'https://fhir.nwgenomics.nhs.uk/StructureDefinition/Observation-Genotype')"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/StructureDefinition-Observation-Panel",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "StructureDefinition-Observation-Panel",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 24435
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TYPE_SPECIFIC_CHECKS_DT_CANONICAL_MULTIPLE_POSSIBLE_VERSIONS"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "There are multiple different potential matches for the url 'http://hl7.org/fhir/StructureDefinition/workflow-supportingInfo'. It might be a good idea to fix to the correct version to reduce the likelihood of a wrong version being selected by an implementation/implementer, or use the [IG Parameter `pin-canonicals`](https://hl7.org/fhir/tools/CodeSystem-ig-parameters.html). Using version '5.2.0', found versions: 4.0.1 (from hl7.fhir.r4.core#4.0.1), 5.1.0 (from hl7.fhir.uv.extensions.r4#5.1.0), 5.2.0 (from hl7.fhir.uv.extensions.r4#5.2.0). Suggested fix: change the canonical reference from 'http://hl7.org/fhir/StructureDefinition/workflow-supportingInfo' to 'http://hl7.org/fhir/StructureDefinition/workflow-supportingInfo|5.2.0'"
            },
            "expression": [
              "StructureDefinition/Observation-Panel: StructureDefinition.snapshot.element[8].type[0].profile[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 88198
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TYPE_SPECIFIC_CHECKS_DT_CANONICAL_RESOLVE"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "A definition could not be found for Canonical URL 'https://nw-gmsa.github.io/ActorDefinition/OrderFiller'"
            },
            "expression": [
              "StructureDefinition/Observation-Panel: StructureDefinition.snapshot.element[60].extension[0].extension[1].value.ofType(canonical)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 88575
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TYPE_SPECIFIC_CHECKS_DT_CANONICAL_RESOLVE"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "A definition could not be found for Canonical URL 'https://nw-gmsa.github.io/ActorDefinition/OrderPlacer'"
            },
            "expression": [
              "StructureDefinition/Observation-Panel: StructureDefinition.snapshot.element[60].extension[1].extension[1].value.ofType(canonical)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 88958
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TYPE_SPECIFIC_CHECKS_DT_CANONICAL_RESOLVE"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "A definition could not be found for Canonical URL 'https://nw-gmsa.github.io/ActorDefinition/AutomationManager'"
            },
            "expression": [
              "StructureDefinition/Observation-Panel: StructureDefinition.snapshot.element[60].extension[2].extension[1].value.ofType(canonical)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 93318
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TYPE_SPECIFIC_CHECKS_DT_CANONICAL_RESOLVE"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "A definition could not be found for Canonical URL 'https://nw-gmsa.github.io/ActorDefinition/OrderFiller'"
            },
            "expression": [
              "StructureDefinition/Observation-Panel: StructureDefinition.snapshot.element[62].extension[0].extension[1].value.ofType(canonical)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 93696
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TYPE_SPECIFIC_CHECKS_DT_CANONICAL_RESOLVE"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "A definition could not be found for Canonical URL 'https://nw-gmsa.github.io/ActorDefinition/OrderPlacer'"
            },
            "expression": [
              "StructureDefinition/Observation-Panel: StructureDefinition.snapshot.element[62].extension[1].extension[1].value.ofType(canonical)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 94080
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TYPE_SPECIFIC_CHECKS_DT_CANONICAL_RESOLVE"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "A definition could not be found for Canonical URL 'https://nw-gmsa.github.io/ActorDefinition/AutomationManager'"
            },
            "expression": [
              "StructureDefinition/Observation-Panel: StructureDefinition.snapshot.element[62].extension[2].extension[1].value.ofType(canonical)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 98709
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TYPE_SPECIFIC_CHECKS_DT_CANONICAL_MULTIPLE_POSSIBLE_VERSIONS"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "There are multiple different potential matches for the url 'http://hl7.org/fhir/StructureDefinition/data-absent-reason'. It might be a good idea to fix to the correct version to reduce the likelihood of a wrong version being selected by an implementation/implementer, or use the [IG Parameter `pin-canonicals`](https://hl7.org/fhir/tools/CodeSystem-ig-parameters.html). Using version '5.2.0', found versions: 4.0.1 (from hl7.fhir.r4.core#4.0.1), 5.1.0 (from hl7.fhir.uv.extensions.r4#5.1.0), 5.2.0 (from hl7.fhir.uv.extensions.r4#5.2.0). Suggested fix: change the canonical reference from 'http://hl7.org/fhir/StructureDefinition/data-absent-reason' to 'http://hl7.org/fhir/StructureDefinition/data-absent-reason|5.2.0'"
            },
            "expression": [
              "StructureDefinition/Observation-Panel: StructureDefinition.snapshot.element[65].type[0].profile[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 104751
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TYPE_SPECIFIC_CHECKS_DT_CANONICAL_MULTIPLE_POSSIBLE_VERSIONS"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "There are multiple different potential matches for the url 'http://hl7.org/fhir/StructureDefinition/event-performerFunction'. It might be a good idea to fix to the correct version to reduce the likelihood of a wrong version being selected by an implementation/implementer, or use the [IG Parameter `pin-canonicals`](https://hl7.org/fhir/tools/CodeSystem-ig-parameters.html). Using version '5.2.0', found versions: 4.0.1 (from hl7.fhir.r4.core#4.0.1), 5.1.0 (from hl7.fhir.uv.extensions.r4#5.1.0), 5.2.0 (from hl7.fhir.uv.extensions.r4#5.2.0). Suggested fix: change the canonical reference from 'http://hl7.org/fhir/StructureDefinition/event-performerFunction' to 'http://hl7.org/fhir/StructureDefinition/event-performerFunction|5.2.0'"
            },
            "expression": [
              "StructureDefinition/Observation-Panel: StructureDefinition.snapshot.element[70].type[0].profile[0]"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/StructureDefinition-Observation-TherapeuticImplication",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "StructureDefinition-Observation-TherapeuticImplication",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 31573
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TERMINOLOGY_TX_SYSTEM_NO_CODE"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "A code with no system has no defined meaning, and it cannot be validated. A system should be provided"
            },
            "expression": [
              "StructureDefinition/Observation-TherapeuticImplication: StructureDefinition.keyword[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 31614
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TERMINOLOGY_TX_SYSTEM_NO_CODE"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "A code with no system has no defined meaning, and it cannot be validated. A system should be provided"
            },
            "expression": [
              "StructureDefinition/Observation-TherapeuticImplication: StructureDefinition.keyword[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 31661
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TERMINOLOGY_TX_SYSTEM_NO_CODE"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "A code with no system has no defined meaning, and it cannot be validated. A system should be provided"
            },
            "expression": [
              "StructureDefinition/Observation-TherapeuticImplication: StructureDefinition.keyword[2]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 46470
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TYPE_SPECIFIC_CHECKS_DT_CANONICAL_MULTIPLE_POSSIBLE_VERSIONS"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "There are multiple different potential matches for the url 'http://hl7.org/fhir/StructureDefinition/observation-secondaryFinding'. It might be a good idea to fix to the correct version to reduce the likelihood of a wrong version being selected by an implementation/implementer, or use the [IG Parameter `pin-canonicals`](https://hl7.org/fhir/tools/CodeSystem-ig-parameters.html). Using version '5.2.0', found versions: 4.0.1 (from hl7.fhir.r4.core#4.0.1), 5.1.0 (from hl7.fhir.uv.extensions.r4#5.1.0), 5.2.0 (from hl7.fhir.uv.extensions.r4#5.2.0). Suggested fix: change the canonical reference from 'http://hl7.org/fhir/StructureDefinition/observation-secondaryFinding' to 'http://hl7.org/fhir/StructureDefinition/observation-secondaryFinding|5.2.0'"
            },
            "expression": [
              "StructureDefinition/Observation-TherapeuticImplication: StructureDefinition.snapshot.element[8].type[0].profile[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 47452
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TYPE_SPECIFIC_CHECKS_DT_CANONICAL_MULTIPLE_POSSIBLE_VERSIONS"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "There are multiple different potential matches for the url 'http://hl7.org/fhir/StructureDefinition/bodySite'. It might be a good idea to fix to the correct version to reduce the likelihood of a wrong version being selected by an implementation/implementer, or use the [IG Parameter `pin-canonicals`](https://hl7.org/fhir/tools/CodeSystem-ig-parameters.html). Using version '5.2.0', found versions: 4.0.1 (from hl7.fhir.r4.core#4.0.1), 5.1.0 (from hl7.fhir.uv.extensions.r4#5.1.0), 5.2.0 (from hl7.fhir.uv.extensions.r4#5.2.0). Suggested fix: change the canonical reference from 'http://hl7.org/fhir/StructureDefinition/bodySite' to 'http://hl7.org/fhir/StructureDefinition/bodySite|5.2.0'"
            },
            "expression": [
              "StructureDefinition/Observation-TherapeuticImplication: StructureDefinition.snapshot.element[9].type[0].profile[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 48734
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TYPE_SPECIFIC_CHECKS_DT_CANONICAL_MULTIPLE_POSSIBLE_VERSIONS"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "There are multiple different potential matches for the url 'http://hl7.org/fhir/StructureDefinition/workflow-relatedArtifact'. It might be a good idea to fix to the correct version to reduce the likelihood of a wrong version being selected by an implementation/implementer, or use the [IG Parameter `pin-canonicals`](https://hl7.org/fhir/tools/CodeSystem-ig-parameters.html). Using version '5.2.0', found versions: 4.0.1 (from hl7.fhir.r4.core#4.0.1), 5.1.0 (from hl7.fhir.uv.extensions.r4#5.1.0), 5.2.0 (from hl7.fhir.uv.extensions.r4#5.2.0). Suggested fix: change the canonical reference from 'http://hl7.org/fhir/StructureDefinition/workflow-relatedArtifact' to 'http://hl7.org/fhir/StructureDefinition/workflow-relatedArtifact|5.2.0'"
            },
            "expression": [
              "StructureDefinition/Observation-TherapeuticImplication: StructureDefinition.snapshot.element[10].type[0].profile[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "Publisher"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The Implementation Guide contains no examples for this profile"
            },
            "expression": [
              "StructureDefinition.where(url = 'https://fhir.nwgenomics.nhs.uk/StructureDefinition/Observation-TherapeuticImplication')"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/StructureDefinition-Observation-Variant",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "StructureDefinition-Observation-Variant",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 40864
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TERMINOLOGY_TX_SYSTEM_NO_CODE"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "A code with no system has no defined meaning, and it cannot be validated. A system should be provided"
            },
            "expression": [
              "StructureDefinition/Observation-Variant: StructureDefinition.keyword[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 40905
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TERMINOLOGY_TX_SYSTEM_NO_CODE"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "A code with no system has no defined meaning, and it cannot be validated. A system should be provided"
            },
            "expression": [
              "StructureDefinition/Observation-Variant: StructureDefinition.keyword[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 40952
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TERMINOLOGY_TX_SYSTEM_NO_CODE"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "A code with no system has no defined meaning, and it cannot be validated. A system should be provided"
            },
            "expression": [
              "StructureDefinition/Observation-Variant: StructureDefinition.keyword[2]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 55729
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TYPE_SPECIFIC_CHECKS_DT_CANONICAL_MULTIPLE_POSSIBLE_VERSIONS"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "There are multiple different potential matches for the url 'http://hl7.org/fhir/StructureDefinition/observation-secondaryFinding'. It might be a good idea to fix to the correct version to reduce the likelihood of a wrong version being selected by an implementation/implementer, or use the [IG Parameter `pin-canonicals`](https://hl7.org/fhir/tools/CodeSystem-ig-parameters.html). Using version '5.2.0', found versions: 4.0.1 (from hl7.fhir.r4.core#4.0.1), 5.1.0 (from hl7.fhir.uv.extensions.r4#5.1.0), 5.2.0 (from hl7.fhir.uv.extensions.r4#5.2.0). Suggested fix: change the canonical reference from 'http://hl7.org/fhir/StructureDefinition/observation-secondaryFinding' to 'http://hl7.org/fhir/StructureDefinition/observation-secondaryFinding|5.2.0'"
            },
            "expression": [
              "StructureDefinition/Observation-Variant: StructureDefinition.snapshot.element[8].type[0].profile[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 56711
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TYPE_SPECIFIC_CHECKS_DT_CANONICAL_MULTIPLE_POSSIBLE_VERSIONS"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "There are multiple different potential matches for the url 'http://hl7.org/fhir/StructureDefinition/bodySite'. It might be a good idea to fix to the correct version to reduce the likelihood of a wrong version being selected by an implementation/implementer, or use the [IG Parameter `pin-canonicals`](https://hl7.org/fhir/tools/CodeSystem-ig-parameters.html). Using version '5.2.0', found versions: 4.0.1 (from hl7.fhir.r4.core#4.0.1), 5.1.0 (from hl7.fhir.uv.extensions.r4#5.1.0), 5.2.0 (from hl7.fhir.uv.extensions.r4#5.2.0). Suggested fix: change the canonical reference from 'http://hl7.org/fhir/StructureDefinition/bodySite' to 'http://hl7.org/fhir/StructureDefinition/bodySite|5.2.0'"
            },
            "expression": [
              "StructureDefinition/Observation-Variant: StructureDefinition.snapshot.element[9].type[0].profile[0]"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/StructureDefinition-Observation",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "StructureDefinition-Observation",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 37709
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TERMINOLOGY_TX_SYSTEM_NO_CODE"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "A code with no system has no defined meaning, and it cannot be validated. A system should be provided"
            },
            "expression": [
              "StructureDefinition/Observation: StructureDefinition.keyword[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 37757
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TERMINOLOGY_TX_SYSTEM_NO_CODE"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "A code with no system has no defined meaning, and it cannot be validated. A system should be provided"
            },
            "expression": [
              "StructureDefinition/Observation: StructureDefinition.keyword[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 37804
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TERMINOLOGY_TX_SYSTEM_NO_CODE"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "A code with no system has no defined meaning, and it cannot be validated. A system should be provided"
            },
            "expression": [
              "StructureDefinition/Observation: StructureDefinition.keyword[2]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 53094
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TYPE_SPECIFIC_CHECKS_DT_CANONICAL_MULTIPLE_POSSIBLE_VERSIONS"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "There are multiple different potential matches for the url 'http://hl7.org/fhir/StructureDefinition/workflow-supportingInfo'. It might be a good idea to fix to the correct version to reduce the likelihood of a wrong version being selected by an implementation/implementer, or use the [IG Parameter `pin-canonicals`](https://hl7.org/fhir/tools/CodeSystem-ig-parameters.html). Using version '5.2.0', found versions: 4.0.1 (from hl7.fhir.r4.core#4.0.1), 5.1.0 (from hl7.fhir.uv.extensions.r4#5.1.0), 5.2.0 (from hl7.fhir.uv.extensions.r4#5.2.0). Suggested fix: change the canonical reference from 'http://hl7.org/fhir/StructureDefinition/workflow-supportingInfo' to 'http://hl7.org/fhir/StructureDefinition/workflow-supportingInfo|5.2.0'"
            },
            "expression": [
              "StructureDefinition/Observation: StructureDefinition.snapshot.element[8].type[0].profile[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 116857
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TYPE_SPECIFIC_CHECKS_DT_CANONICAL_RESOLVE"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "A definition could not be found for Canonical URL 'https://nw-gmsa.github.io/ActorDefinition/OrderFiller'"
            },
            "expression": [
              "StructureDefinition/Observation: StructureDefinition.snapshot.element[60].extension[0].extension[1].value.ofType(canonical)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 117234
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TYPE_SPECIFIC_CHECKS_DT_CANONICAL_RESOLVE"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "A definition could not be found for Canonical URL 'https://nw-gmsa.github.io/ActorDefinition/OrderPlacer'"
            },
            "expression": [
              "StructureDefinition/Observation: StructureDefinition.snapshot.element[60].extension[1].extension[1].value.ofType(canonical)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 117617
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TYPE_SPECIFIC_CHECKS_DT_CANONICAL_RESOLVE"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "A definition could not be found for Canonical URL 'https://nw-gmsa.github.io/ActorDefinition/AutomationManager'"
            },
            "expression": [
              "StructureDefinition/Observation: StructureDefinition.snapshot.element[60].extension[2].extension[1].value.ofType(canonical)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 121977
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TYPE_SPECIFIC_CHECKS_DT_CANONICAL_RESOLVE"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "A definition could not be found for Canonical URL 'https://nw-gmsa.github.io/ActorDefinition/OrderFiller'"
            },
            "expression": [
              "StructureDefinition/Observation: StructureDefinition.snapshot.element[62].extension[0].extension[1].value.ofType(canonical)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 122355
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TYPE_SPECIFIC_CHECKS_DT_CANONICAL_RESOLVE"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "A definition could not be found for Canonical URL 'https://nw-gmsa.github.io/ActorDefinition/OrderPlacer'"
            },
            "expression": [
              "StructureDefinition/Observation: StructureDefinition.snapshot.element[62].extension[1].extension[1].value.ofType(canonical)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 122739
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TYPE_SPECIFIC_CHECKS_DT_CANONICAL_RESOLVE"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "A definition could not be found for Canonical URL 'https://nw-gmsa.github.io/ActorDefinition/AutomationManager'"
            },
            "expression": [
              "StructureDefinition/Observation: StructureDefinition.snapshot.element[62].extension[2].extension[1].value.ofType(canonical)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 127368
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TYPE_SPECIFIC_CHECKS_DT_CANONICAL_MULTIPLE_POSSIBLE_VERSIONS"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "There are multiple different potential matches for the url 'http://hl7.org/fhir/StructureDefinition/data-absent-reason'. It might be a good idea to fix to the correct version to reduce the likelihood of a wrong version being selected by an implementation/implementer, or use the [IG Parameter `pin-canonicals`](https://hl7.org/fhir/tools/CodeSystem-ig-parameters.html). Using version '5.2.0', found versions: 4.0.1 (from hl7.fhir.r4.core#4.0.1), 5.1.0 (from hl7.fhir.uv.extensions.r4#5.1.0), 5.2.0 (from hl7.fhir.uv.extensions.r4#5.2.0). Suggested fix: change the canonical reference from 'http://hl7.org/fhir/StructureDefinition/data-absent-reason' to 'http://hl7.org/fhir/StructureDefinition/data-absent-reason|5.2.0'"
            },
            "expression": [
              "StructureDefinition/Observation: StructureDefinition.snapshot.element[65].type[0].profile[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 133410
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TYPE_SPECIFIC_CHECKS_DT_CANONICAL_MULTIPLE_POSSIBLE_VERSIONS"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "There are multiple different potential matches for the url 'http://hl7.org/fhir/StructureDefinition/event-performerFunction'. It might be a good idea to fix to the correct version to reduce the likelihood of a wrong version being selected by an implementation/implementer, or use the [IG Parameter `pin-canonicals`](https://hl7.org/fhir/tools/CodeSystem-ig-parameters.html). Using version '5.2.0', found versions: 4.0.1 (from hl7.fhir.r4.core#4.0.1), 5.1.0 (from hl7.fhir.uv.extensions.r4#5.1.0), 5.2.0 (from hl7.fhir.uv.extensions.r4#5.2.0). Suggested fix: change the canonical reference from 'http://hl7.org/fhir/StructureDefinition/event-performerFunction' to 'http://hl7.org/fhir/StructureDefinition/event-performerFunction|5.2.0'"
            },
            "expression": [
              "StructureDefinition/Observation: StructureDefinition.snapshot.element[70].type[0].profile[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 216471
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TYPE_SPECIFIC_CHECKS_DT_CANONICAL_RESOLVE"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "A definition could not be found for Canonical URL 'https://nw-gmsa.github.io/ActorDefinition/OrderFiller'"
            },
            "expression": [
              "StructureDefinition/Observation: StructureDefinition.differential.element[8].extension[0].extension[1].value.ofType(canonical)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 216688
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TYPE_SPECIFIC_CHECKS_DT_CANONICAL_RESOLVE"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "A definition could not be found for Canonical URL 'https://nw-gmsa.github.io/ActorDefinition/OrderPlacer'"
            },
            "expression": [
              "StructureDefinition/Observation: StructureDefinition.differential.element[8].extension[1].extension[1].value.ofType(canonical)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 216911
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TYPE_SPECIFIC_CHECKS_DT_CANONICAL_RESOLVE"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "A definition could not be found for Canonical URL 'https://nw-gmsa.github.io/ActorDefinition/AutomationManager'"
            },
            "expression": [
              "StructureDefinition/Observation: StructureDefinition.differential.element[8].extension[2].extension[1].value.ofType(canonical)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 217337
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TYPE_SPECIFIC_CHECKS_DT_CANONICAL_RESOLVE"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "A definition could not be found for Canonical URL 'https://nw-gmsa.github.io/ActorDefinition/OrderFiller'"
            },
            "expression": [
              "StructureDefinition/Observation: StructureDefinition.differential.element[9].extension[0].extension[1].value.ofType(canonical)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 217555
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TYPE_SPECIFIC_CHECKS_DT_CANONICAL_RESOLVE"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "A definition could not be found for Canonical URL 'https://nw-gmsa.github.io/ActorDefinition/OrderPlacer'"
            },
            "expression": [
              "StructureDefinition/Observation: StructureDefinition.differential.element[9].extension[1].extension[1].value.ofType(canonical)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 217779
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TYPE_SPECIFIC_CHECKS_DT_CANONICAL_RESOLVE"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "A definition could not be found for Canonical URL 'https://nw-gmsa.github.io/ActorDefinition/AutomationManager'"
            },
            "expression": [
              "StructureDefinition/Observation: StructureDefinition.differential.element[9].extension[2].extension[1].value.ofType(canonical)"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/StructureDefinition-OperationOutcome",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "StructureDefinition-OperationOutcome"
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/StructureDefinition-OrderGroupNumber",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "StructureDefinition-OrderGroupNumber",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "Publisher"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The Implementation Guide contains no examples for this data type profile"
            },
            "expression": [
              "StructureDefinition.where(url = 'https://fhir.nwgenomics.nhs.uk/StructureDefinition/OrderGroupNumber')"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/StructureDefinition-OrderIdentifier",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "StructureDefinition-OrderIdentifier"
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/StructureDefinition-OrganisationCode",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "StructureDefinition-OrganisationCode",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10714
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TERMINOLOGY_TX_SYSTEM_NO_CODE"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "A code with no system has no defined meaning, and it cannot be validated. A system should be provided"
            },
            "expression": [
              "StructureDefinition/OrganisationCode: StructureDefinition.keyword[0]"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/StructureDefinition-OrganisationSiteIdentifier",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "StructureDefinition-OrganisationSiteIdentifier",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10690
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TERMINOLOGY_TX_SYSTEM_NO_CODE"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "A code with no system has no defined meaning, and it cannot be validated. A system should be provided"
            },
            "expression": [
              "StructureDefinition/OrganisationSiteIdentifier: StructureDefinition.keyword[0]"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/StructureDefinition-Organization",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "StructureDefinition-Organization",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 22846
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TERMINOLOGY_TX_SYSTEM_NO_CODE"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "A code with no system has no defined meaning, and it cannot be validated. A system should be provided"
            },
            "expression": [
              "StructureDefinition/Organization: StructureDefinition.keyword[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 22888
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TERMINOLOGY_TX_SYSTEM_NO_CODE"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "A code with no system has no defined meaning, and it cannot be validated. A system should be provided"
            },
            "expression": [
              "StructureDefinition/Organization: StructureDefinition.keyword[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 38171
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TYPE_SPECIFIC_CHECKS_DT_CANONICAL_MULTIPLE_POSSIBLE_VERSIONS"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "There are multiple different potential matches for the url 'http://hl7.org/fhir/StructureDefinition/organization-period'. It might be a good idea to fix to the correct version to reduce the likelihood of a wrong version being selected by an implementation/implementer, or use the [IG Parameter `pin-canonicals`](https://hl7.org/fhir/tools/CodeSystem-ig-parameters.html). Using version '5.2.0', found versions: 4.0.1 (from hl7.fhir.r4.core#4.0.1), 5.1.0 (from hl7.fhir.uv.extensions.r4#5.1.0), 5.2.0 (from hl7.fhir.uv.extensions.r4#5.2.0). Suggested fix: change the canonical reference from 'http://hl7.org/fhir/StructureDefinition/organization-period' to 'http://hl7.org/fhir/StructureDefinition/organization-period|5.2.0'"
            },
            "expression": [
              "StructureDefinition/Organization: StructureDefinition.snapshot.element[9].type[0].profile[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 89536
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TYPE_SPECIFIC_CHECKS_DT_CANONICAL_MULTIPLE_POSSIBLE_VERSIONS"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "There are multiple different potential matches for the url 'http://hl7.org/fhir/StructureDefinition/geolocation'. It might be a good idea to fix to the correct version to reduce the likelihood of a wrong version being selected by an implementation/implementer, or use the [IG Parameter `pin-canonicals`](https://hl7.org/fhir/tools/CodeSystem-ig-parameters.html). Using version '5.2.0', found versions: 4.0.1 (from hl7.fhir.r4.core#4.0.1), 5.1.0 (from hl7.fhir.uv.extensions.r4#5.1.0), 5.2.0 (from hl7.fhir.uv.extensions.r4#5.2.0). Suggested fix: change the canonical reference from 'http://hl7.org/fhir/StructureDefinition/geolocation' to 'http://hl7.org/fhir/StructureDefinition/geolocation|5.2.0'"
            },
            "expression": [
              "StructureDefinition/Organization: StructureDefinition.snapshot.element[50].type[0].profile[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 112721
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TYPE_SPECIFIC_CHECKS_DT_CANONICAL_MULTIPLE_POSSIBLE_VERSIONS"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "There are multiple different potential matches for the url 'http://hl7.org/fhir/StructureDefinition/geolocation'. It might be a good idea to fix to the correct version to reduce the likelihood of a wrong version being selected by an implementation/implementer, or use the [IG Parameter `pin-canonicals`](https://hl7.org/fhir/tools/CodeSystem-ig-parameters.html). Using version '5.2.0', found versions: 4.0.1 (from hl7.fhir.r4.core#4.0.1), 5.1.0 (from hl7.fhir.uv.extensions.r4#5.1.0), 5.2.0 (from hl7.fhir.uv.extensions.r4#5.2.0). Suggested fix: change the canonical reference from 'http://hl7.org/fhir/StructureDefinition/geolocation' to 'http://hl7.org/fhir/StructureDefinition/geolocation|5.2.0'"
            },
            "expression": [
              "StructureDefinition/Organization: StructureDefinition.differential.element[6].type[0].profile[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 111777
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "The slice 'odsOrganisationCode' on path 'Organization.identifier' is not marked as 'must-support' which is not consistent with the element that defines the slicing, where 'must-support' is true"
            },
            "expression": [
              "StructureDefinition/Organization: StructureDefinition.snapshot"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 111777
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "The slice 'odsSiteCode' on path 'Organization.identifier' is not marked as 'must-support' which is not consistent with the element that defines the slicing, where 'must-support' is true"
            },
            "expression": [
              "StructureDefinition/Organization: StructureDefinition.snapshot"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/StructureDefinition-Patient",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "StructureDefinition-Patient",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 47908
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TERMINOLOGY_TX_SYSTEM_NO_CODE"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "A code with no system has no defined meaning, and it cannot be validated. A system should be provided"
            },
            "expression": [
              "StructureDefinition/Patient: StructureDefinition.keyword[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 47958
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TERMINOLOGY_TX_SYSTEM_NO_CODE"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "A code with no system has no defined meaning, and it cannot be validated. A system should be provided"
            },
            "expression": [
              "StructureDefinition/Patient: StructureDefinition.keyword[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 60274
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TYPE_SPECIFIC_CHECKS_DT_CANONICAL_MULTIPLE_POSSIBLE_VERSIONS"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "There are multiple different potential matches for the url 'http://hl7.org/fhir/StructureDefinition/patient-birthPlace'. It might be a good idea to fix to the correct version to reduce the likelihood of a wrong version being selected by an implementation/implementer, or use the [IG Parameter `pin-canonicals`](https://hl7.org/fhir/tools/CodeSystem-ig-parameters.html). Using version '5.2.0', found versions: 4.0.1 (from hl7.fhir.r4.core#4.0.1), 5.1.0 (from hl7.fhir.uv.extensions.r4#5.1.0), 5.2.0 (from hl7.fhir.uv.extensions.r4#5.2.0). Suggested fix: change the canonical reference from 'http://hl7.org/fhir/StructureDefinition/patient-birthPlace' to 'http://hl7.org/fhir/StructureDefinition/patient-birthPlace|5.2.0'"
            },
            "expression": [
              "StructureDefinition/Patient: StructureDefinition.snapshot.element[8].type[0].profile[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 64535
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TYPE_SPECIFIC_CHECKS_DT_CANONICAL_MULTIPLE_POSSIBLE_VERSIONS"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "There are multiple different potential matches for the url 'http://hl7.org/fhir/StructureDefinition/patient-sexParameterForClinicalUse'. It might be a good idea to fix to the correct version to reduce the likelihood of a wrong version being selected by an implementation/implementer, or use the [IG Parameter `pin-canonicals`](https://hl7.org/fhir/tools/CodeSystem-ig-parameters.html). Using version '5.2.0', found versions: 5.1.0 (from hl7.fhir.uv.extensions.r4#5.1.0), 5.2.0 (from hl7.fhir.uv.extensions.r4#5.2.0). Suggested fix: change the canonical reference from 'http://hl7.org/fhir/StructureDefinition/patient-sexParameterForClinicalUse' to 'http://hl7.org/fhir/StructureDefinition/patient-sexParameterForClinicalUse|5.2.0'"
            },
            "expression": [
              "StructureDefinition/Patient: StructureDefinition.snapshot.element[13].type[0].profile[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 167888
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TYPE_SPECIFIC_CHECKS_DT_CANONICAL_MULTIPLE_POSSIBLE_VERSIONS"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "There are multiple different potential matches for the url 'http://hl7.org/fhir/StructureDefinition/data-absent-reason'. It might be a good idea to fix to the correct version to reduce the likelihood of a wrong version being selected by an implementation/implementer, or use the [IG Parameter `pin-canonicals`](https://hl7.org/fhir/tools/CodeSystem-ig-parameters.html). Using version '5.2.0', found versions: 4.0.1 (from hl7.fhir.r4.core#4.0.1), 5.1.0 (from hl7.fhir.uv.extensions.r4#5.1.0), 5.2.0 (from hl7.fhir.uv.extensions.r4#5.2.0). Suggested fix: change the canonical reference from 'http://hl7.org/fhir/StructureDefinition/data-absent-reason' to 'http://hl7.org/fhir/StructureDefinition/data-absent-reason|5.2.0'"
            },
            "expression": [
              "StructureDefinition/Patient: StructureDefinition.snapshot.element[89].type[0].profile[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 174109
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TYPE_SPECIFIC_CHECKS_DT_CANONICAL_MULTIPLE_POSSIBLE_VERSIONS"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "There are multiple different potential matches for the url 'http://hl7.org/fhir/StructureDefinition/humanname-fathers-family'. It might be a good idea to fix to the correct version to reduce the likelihood of a wrong version being selected by an implementation/implementer, or use the [IG Parameter `pin-canonicals`](https://hl7.org/fhir/tools/CodeSystem-ig-parameters.html). Using version '5.2.0', found versions: 4.0.1 (from hl7.fhir.r4.core#4.0.1), 5.1.0 (from hl7.fhir.uv.extensions.r4#5.1.0), 5.2.0 (from hl7.fhir.uv.extensions.r4#5.2.0). Suggested fix: change the canonical reference from 'http://hl7.org/fhir/StructureDefinition/humanname-fathers-family' to 'http://hl7.org/fhir/StructureDefinition/humanname-fathers-family|5.2.0'"
            },
            "expression": [
              "StructureDefinition/Patient: StructureDefinition.snapshot.element[95].type[0].profile[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 175142
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TYPE_SPECIFIC_CHECKS_DT_CANONICAL_MULTIPLE_POSSIBLE_VERSIONS"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "There are multiple different potential matches for the url 'http://hl7.org/fhir/StructureDefinition/humanname-mothers-family'. It might be a good idea to fix to the correct version to reduce the likelihood of a wrong version being selected by an implementation/implementer, or use the [IG Parameter `pin-canonicals`](https://hl7.org/fhir/tools/CodeSystem-ig-parameters.html). Using version '5.2.0', found versions: 4.0.1 (from hl7.fhir.r4.core#4.0.1), 5.1.0 (from hl7.fhir.uv.extensions.r4#5.1.0), 5.2.0 (from hl7.fhir.uv.extensions.r4#5.2.0). Suggested fix: change the canonical reference from 'http://hl7.org/fhir/StructureDefinition/humanname-mothers-family' to 'http://hl7.org/fhir/StructureDefinition/humanname-mothers-family|5.2.0'"
            },
            "expression": [
              "StructureDefinition/Patient: StructureDefinition.snapshot.element[96].type[0].profile[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 197817
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TYPE_SPECIFIC_CHECKS_DT_CANONICAL_MULTIPLE_POSSIBLE_VERSIONS"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "There are multiple different potential matches for the url 'http://hl7.org/fhir/StructureDefinition/iso21090-ADXP-streetName'. It might be a good idea to fix to the correct version to reduce the likelihood of a wrong version being selected by an implementation/implementer, or use the [IG Parameter `pin-canonicals`](https://hl7.org/fhir/tools/CodeSystem-ig-parameters.html). Using version '5.2.0', found versions: 4.0.1 (from hl7.fhir.r4.core#4.0.1), 5.1.0 (from hl7.fhir.uv.extensions.r4#5.1.0), 5.2.0 (from hl7.fhir.uv.extensions.r4#5.2.0). Suggested fix: change the canonical reference from 'http://hl7.org/fhir/StructureDefinition/iso21090-ADXP-streetName' to 'http://hl7.org/fhir/StructureDefinition/iso21090-ADXP-streetName|5.2.0'"
            },
            "expression": [
              "StructureDefinition/Patient: StructureDefinition.snapshot.element[116].type[0].profile[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 198829
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TYPE_SPECIFIC_CHECKS_DT_CANONICAL_MULTIPLE_POSSIBLE_VERSIONS"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "There are multiple different potential matches for the url 'http://hl7.org/fhir/StructureDefinition/iso21090-ADXP-houseNumber'. It might be a good idea to fix to the correct version to reduce the likelihood of a wrong version being selected by an implementation/implementer, or use the [IG Parameter `pin-canonicals`](https://hl7.org/fhir/tools/CodeSystem-ig-parameters.html). Using version '5.2.0', found versions: 4.0.1 (from hl7.fhir.r4.core#4.0.1), 5.1.0 (from hl7.fhir.uv.extensions.r4#5.1.0), 5.2.0 (from hl7.fhir.uv.extensions.r4#5.2.0). Suggested fix: change the canonical reference from 'http://hl7.org/fhir/StructureDefinition/iso21090-ADXP-houseNumber' to 'http://hl7.org/fhir/StructureDefinition/iso21090-ADXP-houseNumber|5.2.0'"
            },
            "expression": [
              "StructureDefinition/Patient: StructureDefinition.snapshot.element[117].type[0].profile[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 199708
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TYPE_SPECIFIC_CHECKS_DT_CANONICAL_MULTIPLE_POSSIBLE_VERSIONS"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "There are multiple different potential matches for the url 'http://hl7.org/fhir/StructureDefinition/iso21090-ADXP-postBox'. It might be a good idea to fix to the correct version to reduce the likelihood of a wrong version being selected by an implementation/implementer, or use the [IG Parameter `pin-canonicals`](https://hl7.org/fhir/tools/CodeSystem-ig-parameters.html). Using version '5.2.0', found versions: 4.0.1 (from hl7.fhir.r4.core#4.0.1), 5.1.0 (from hl7.fhir.uv.extensions.r4#5.1.0), 5.2.0 (from hl7.fhir.uv.extensions.r4#5.2.0). Suggested fix: change the canonical reference from 'http://hl7.org/fhir/StructureDefinition/iso21090-ADXP-postBox' to 'http://hl7.org/fhir/StructureDefinition/iso21090-ADXP-postBox|5.2.0'"
            },
            "expression": [
              "StructureDefinition/Patient: StructureDefinition.snapshot.element[118].type[0].profile[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 206928
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TYPE_SPECIFIC_CHECKS_DT_CANONICAL_MULTIPLE_POSSIBLE_VERSIONS"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "There are multiple different potential matches for the url 'http://hl7.org/fhir/StructureDefinition/iso21090-SC-coding'. It might be a good idea to fix to the correct version to reduce the likelihood of a wrong version being selected by an implementation/implementer, or use the [IG Parameter `pin-canonicals`](https://hl7.org/fhir/tools/CodeSystem-ig-parameters.html). Using version '5.2.0', found versions: 4.0.1 (from hl7.fhir.r4.core#4.0.1), 5.2.0 (from hl7.fhir.uv.extensions.r4#5.2.0). Suggested fix: change the canonical reference from 'http://hl7.org/fhir/StructureDefinition/iso21090-SC-coding' to 'http://hl7.org/fhir/StructureDefinition/iso21090-SC-coding|5.2.0'"
            },
            "expression": [
              "StructureDefinition/Patient: StructureDefinition.snapshot.element[127].type[0].profile[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "SD_VALUE_COMPLEX_FIXED"
              }
            ],
            "severity": "warning",
            "code": "exception",
            "details": {
              "text": "For the complex type CodeableConcept, consider using a pattern rather than a fixed value to avoid over-constraining the instance"
            },
            "expression": [
              "StructureDefinition/Patient: StructureDefinition.snapshot.element[43].fixed.ofType(CodeableConcept)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "SD_VALUE_COMPLEX_FIXED"
              }
            ],
            "severity": "warning",
            "code": "exception",
            "details": {
              "text": "For the complex type CodeableConcept, consider using a pattern rather than a fixed value to avoid over-constraining the instance"
            },
            "expression": [
              "StructureDefinition/Patient: StructureDefinition.snapshot.element[66].fixed.ofType(CodeableConcept)"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/StructureDefinition-Practitioner",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "StructureDefinition-Practitioner",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 18385
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TERMINOLOGY_TX_SYSTEM_NO_CODE"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "A code with no system has no defined meaning, and it cannot be validated. A system should be provided"
            },
            "expression": [
              "StructureDefinition/Practitioner: StructureDefinition.keyword[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 18427
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TERMINOLOGY_TX_SYSTEM_NO_CODE"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "A code with no system has no defined meaning, and it cannot be validated. A system should be provided"
            },
            "expression": [
              "StructureDefinition/Practitioner: StructureDefinition.keyword[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "SD_VALUE_COMPLEX_FIXED"
              }
            ],
            "severity": "warning",
            "code": "exception",
            "details": {
              "text": "For the complex type Coding, consider using a pattern rather than a fixed value to avoid over-constraining the instance"
            },
            "expression": [
              "StructureDefinition/Practitioner: StructureDefinition.snapshot.element[25].fixed.ofType(Coding)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "Publisher"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The Implementation Guide contains no examples for this profile"
            },
            "expression": [
              "StructureDefinition.where(url = 'https://fhir.nwgenomics.nhs.uk/StructureDefinition/Practitioner')"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/StructureDefinition-PractitionerIdentifier",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "StructureDefinition-PractitionerIdentifier",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 18479
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TERMINOLOGY_TX_SYSTEM_NO_CODE"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "A code with no system has no defined meaning, and it cannot be validated. A system should be provided"
            },
            "expression": [
              "StructureDefinition/PractitionerIdentifier: StructureDefinition.keyword[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "SD_VALUE_COMPLEX_FIXED"
              }
            ],
            "severity": "warning",
            "code": "exception",
            "details": {
              "text": "For the complex type Coding, consider using a pattern rather than a fixed value to avoid over-constraining the instance"
            },
            "expression": [
              "StructureDefinition/PractitionerIdentifier: StructureDefinition.snapshot.element[7].fixed.ofType(Coding)"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/StructureDefinition-PractitionerRole",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "StructureDefinition-PractitionerRole",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 28933
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TERMINOLOGY_TX_SYSTEM_NO_CODE"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "A code with no system has no defined meaning, and it cannot be validated. A system should be provided"
            },
            "expression": [
              "StructureDefinition/PractitionerRole: StructureDefinition.keyword[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 28975
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TERMINOLOGY_TX_SYSTEM_NO_CODE"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "A code with no system has no defined meaning, and it cannot be validated. A system should be provided"
            },
            "expression": [
              "StructureDefinition/PractitionerRole: StructureDefinition.keyword[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "SD_VALUE_COMPLEX_FIXED"
              }
            ],
            "severity": "warning",
            "code": "exception",
            "details": {
              "text": "For the complex type Coding, consider using a pattern rather than a fixed value to avoid over-constraining the instance"
            },
            "expression": [
              "StructureDefinition/PractitionerRole: StructureDefinition.snapshot.element[24].fixed.ofType(Coding)"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/StructureDefinition-Procedure-GenomicStudy",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "StructureDefinition-Procedure-GenomicStudy",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 12084
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TERMINOLOGY_TX_SYSTEM_NO_CODE"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "A code with no system has no defined meaning, and it cannot be validated. A system should be provided"
            },
            "expression": [
              "StructureDefinition/Procedure-GenomicStudy: StructureDefinition.keyword[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 12125
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TERMINOLOGY_TX_SYSTEM_NO_CODE"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "A code with no system has no defined meaning, and it cannot be validated. A system should be provided"
            },
            "expression": [
              "StructureDefinition/Procedure-GenomicStudy: StructureDefinition.keyword[1]"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/StructureDefinition-Procedure",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "StructureDefinition-Procedure"
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/StructureDefinition-QuestionnaireResponse",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "StructureDefinition-QuestionnaireResponse",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "Publisher"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The Implementation Guide contains no examples for this profile"
            },
            "expression": [
              "StructureDefinition.where(url = 'https://fhir.nwgenomics.nhs.uk/StructureDefinition/QuestionnaireResponse')"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/StructureDefinition-RelatedPerson",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "StructureDefinition-RelatedPerson",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 7109
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TERMINOLOGY_TX_SYSTEM_NO_CODE"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "A code with no system has no defined meaning, and it cannot be validated. A system should be provided"
            },
            "expression": [
              "StructureDefinition/RelatedPerson: StructureDefinition.keyword[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 7159
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TERMINOLOGY_TX_SYSTEM_NO_CODE"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "A code with no system has no defined meaning, and it cannot be validated. A system should be provided"
            },
            "expression": [
              "StructureDefinition/RelatedPerson: StructureDefinition.keyword[1]"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/StructureDefinition-ReportIdentifier",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "StructureDefinition-ReportIdentifier"
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/StructureDefinition-ServiceRequest",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "StructureDefinition-ServiceRequest",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 99010
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TERMINOLOGY_TX_SYSTEM_NO_CODE"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "A code with no system has no defined meaning, and it cannot be validated. A system should be provided"
            },
            "expression": [
              "StructureDefinition/ServiceRequest: StructureDefinition.keyword[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 99057
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TERMINOLOGY_TX_SYSTEM_NO_CODE"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "A code with no system has no defined meaning, and it cannot be validated. A system should be provided"
            },
            "expression": [
              "StructureDefinition/ServiceRequest: StructureDefinition.keyword[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 99098
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TERMINOLOGY_TX_SYSTEM_NO_CODE"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "A code with no system has no defined meaning, and it cannot be validated. A system should be provided"
            },
            "expression": [
              "StructureDefinition/ServiceRequest: StructureDefinition.keyword[2]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 262137
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TYPE_SPECIFIC_CHECKS_DT_CANONICAL_MULTIPLE_POSSIBLE_VERSIONS"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "There are multiple different potential matches for the url 'http://terminology.hl7.org/ValueSet/v3-ServiceDeliveryLocationRoleType'. It might be a good idea to fix to the correct version to reduce the likelihood of a wrong version being selected by an implementation/implementer, or use the [IG Parameter `pin-canonicals`](https://hl7.org/fhir/tools/CodeSystem-ig-parameters.html). Using version '3.0.0', found versions: 2.0.0 (from hl7.terminology.r4#5.0.0), 3.0.0 (from hl7.terminology.r4#7.0.1). Suggested fix: change the canonical reference from 'http://terminology.hl7.org/ValueSet/v3-ServiceDeliveryLocationRoleType' to 'http://terminology.hl7.org/ValueSet/v3-ServiceDeliveryLocationRoleType|3.0.0'"
            },
            "expression": [
              "StructureDefinition/ServiceRequest: StructureDefinition.snapshot.element[111].binding.valueSet"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/StructureDefinition-ShipmentTrackingNumber",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "StructureDefinition-ShipmentTrackingNumber",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "Publisher"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The Implementation Guide contains no examples for this data type profile"
            },
            "expression": [
              "StructureDefinition.where(url = 'https://fhir.nwgenomics.nhs.uk/StructureDefinition/ShipmentTrackingNumber')"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/StructureDefinition-Specimen",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "StructureDefinition-Specimen",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 53925
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TERMINOLOGY_TX_SYSTEM_NO_CODE"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "A code with no system has no defined meaning, and it cannot be validated. A system should be provided"
            },
            "expression": [
              "StructureDefinition/Specimen: StructureDefinition.keyword[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 53972
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TERMINOLOGY_TX_SYSTEM_NO_CODE"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "A code with no system has no defined meaning, and it cannot be validated. A system should be provided"
            },
            "expression": [
              "StructureDefinition/Specimen: StructureDefinition.keyword[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 54013
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TERMINOLOGY_TX_SYSTEM_NO_CODE"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "A code with no system has no defined meaning, and it cannot be validated. A system should be provided"
            },
            "expression": [
              "StructureDefinition/Specimen: StructureDefinition.keyword[2]"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/StructureDefinition-SpecimenAccessionNumber",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "StructureDefinition-SpecimenAccessionNumber",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 16328
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TERMINOLOGY_TX_SYSTEM_NO_CODE"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "A code with no system has no defined meaning, and it cannot be validated. A system should be provided"
            },
            "expression": [
              "StructureDefinition/SpecimenAccessionNumber: StructureDefinition.keyword[0]"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/StructureDefinition-Task",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "StructureDefinition-Task",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 31105
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TERMINOLOGY_TX_SYSTEM_NO_CODE"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "A code with no system has no defined meaning, and it cannot be validated. A system should be provided"
            },
            "expression": [
              "StructureDefinition/Task: StructureDefinition.keyword[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 31159
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TERMINOLOGY_TX_SYSTEM_NO_CODE"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "A code with no system has no defined meaning, and it cannot be validated. A system should be provided"
            },
            "expression": [
              "StructureDefinition/Task: StructureDefinition.keyword[1]"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/StructureDefinition-Visit",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "StructureDefinition-Visit",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 53383
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TERMINOLOGY_TX_SYSTEM_NO_CODE"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "A code with no system has no defined meaning, and it cannot be validated. A system should be provided"
            },
            "expression": [
              "StructureDefinition/Visit: StructureDefinition.keyword[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 53433
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TERMINOLOGY_TX_SYSTEM_NO_CODE"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "A code with no system has no defined meaning, and it cannot be validated. A system should be provided"
            },
            "expression": [
              "StructureDefinition/Visit: StructureDefinition.keyword[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 108474
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TYPE_SPECIFIC_CHECKS_DT_CANONICAL_MULTIPLE_POSSIBLE_VERSIONS"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "There are multiple different potential matches for the url 'http://terminology.hl7.org/ValueSet/v3-ActEncounterCode'. It might be a good idea to fix to the correct version to reduce the likelihood of a wrong version being selected by an implementation/implementer, or use the [IG Parameter `pin-canonicals`](https://hl7.org/fhir/tools/CodeSystem-ig-parameters.html). Using version '3.0.0', found versions: 2.0.0 (from hl7.terminology.r4#5.0.0), 3.0.0 (from hl7.terminology.r4#7.0.1). Suggested fix: change the canonical reference from 'http://terminology.hl7.org/ValueSet/v3-ActEncounterCode' to 'http://terminology.hl7.org/ValueSet/v3-ActEncounterCode|3.0.0'"
            },
            "expression": [
              "StructureDefinition/Visit: StructureDefinition.snapshot.element[38].binding.valueSet"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 115496
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TYPE_SPECIFIC_CHECKS_DT_CANONICAL_MULTIPLE_POSSIBLE_VERSIONS"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "There are multiple different potential matches for the url 'http://terminology.hl7.org/ValueSet/v3-ActEncounterCode'. It might be a good idea to fix to the correct version to reduce the likelihood of a wrong version being selected by an implementation/implementer, or use the [IG Parameter `pin-canonicals`](https://hl7.org/fhir/tools/CodeSystem-ig-parameters.html). Using version '3.0.0', found versions: 2.0.0 (from hl7.terminology.r4#5.0.0), 3.0.0 (from hl7.terminology.r4#7.0.1). Suggested fix: change the canonical reference from 'http://terminology.hl7.org/ValueSet/v3-ActEncounterCode' to 'http://terminology.hl7.org/ValueSet/v3-ActEncounterCode|3.0.0'"
            },
            "expression": [
              "StructureDefinition/Visit: StructureDefinition.snapshot.element[43].binding.valueSet"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 118852
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TYPE_SPECIFIC_CHECKS_DT_CANONICAL_MULTIPLE_POSSIBLE_VERSIONS"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "There are multiple different potential matches for the url 'http://terminology.hl7.org/ValueSet/v3-ActPriority'. It might be a good idea to fix to the correct version to reduce the likelihood of a wrong version being selected by an implementation/implementer, or use the [IG Parameter `pin-canonicals`](https://hl7.org/fhir/tools/CodeSystem-ig-parameters.html). Using version '3.0.0', found versions: 2.0.0 (from hl7.terminology.r4#5.0.0), 3.0.0 (from hl7.terminology.r4#7.0.1). Suggested fix: change the canonical reference from 'http://terminology.hl7.org/ValueSet/v3-ActPriority' to 'http://terminology.hl7.org/ValueSet/v3-ActPriority|3.0.0'"
            },
            "expression": [
              "StructureDefinition/Visit: StructureDefinition.snapshot.element[47].binding.valueSet"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "Publisher"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The Implementation Guide contains no examples for this profile"
            },
            "expression": [
              "StructureDefinition.where(url = 'https://fhir.nwgenomics.nhs.uk/StructureDefinition/Visit')"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/StructureDefinition-VisitNumber",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "StructureDefinition-VisitNumber",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "Publisher"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The Implementation Guide contains no examples for this data type profile"
            },
            "expression": [
              "StructureDefinition.where(url = 'https://fhir.nwgenomics.nhs.uk/StructureDefinition/VisitNumber')"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/StructureDefinition-ext-codeable-reference",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "StructureDefinition-ext-codeable-reference",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "SD_CONTEXT_SHOULD_NOT_BE_ELEMENT"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "Review the extension type for ext-codeable-reference: extensions should not have a context of Element unless it's really intended that they can be used anywhere"
            },
            "expression": [
              "StructureDefinition/ext-codeable-reference: StructureDefinition.context[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "Publisher"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The Implementation Guide contains no examples for this extension"
            },
            "expression": [
              "StructureDefinition.where(url = 'https://fhir.nwgenomics.nhs.uk/StructureDefinition/ext-codeable-reference')"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/Task-TaskGenomicOrderCompleted",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Task-TaskGenomicOrderCompleted",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 79
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "UNKNOWN_CODESYSTEM"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'http://hl7.org/fhir/task-inputoutput-parameter-type' could not be found, so the code cannot be validated"
            },
            "expression": [
              "Task/TaskGenomicOrderCompleted: Task.output[0].type.coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 83
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 76
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              }
            ],
            "severity": "error",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'http://hl7.org/fhir/task-inputoutput-parameter-type'"
            },
            "expression": [
              "Task/TaskGenomicOrderCompleted: Task.output[0].type.coding[0].system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/Task-TaskGenomicOrderRequested",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Task-TaskGenomicOrderRequested"
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/ValueSet-GenomicCancer",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ValueSet-GenomicCancer"
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/ValueSet-GenomicClinicalIndicationCodes",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ValueSet-GenomicClinicalIndicationCodes"
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/ValueSet-GenomicDisorderCarrier",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ValueSet-GenomicDisorderCarrier"
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/ValueSet-GenomicFinding",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ValueSet-GenomicFinding"
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/ValueSet-GenomicFindingDetected",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ValueSet-GenomicFindingDetected"
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/ValueSet-GenomicRareAndInheritedDisease",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ValueSet-GenomicRareAndInheritedDisease"
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/ValueSet-GenomicTestCodes",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ValueSet-GenomicTestCodes"
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/ValueSet-GenomicTestOutcomeCodes",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ValueSet-GenomicTestOutcomeCodes"
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/ValueSet-NWIdentifierType",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ValueSet-NWIdentifierType",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1283
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "There are multiple different potential matches for the url 'http://terminology.hl7.org/CodeSystem/v2-0203'. It might be a good idea to fix to the correct version to reduce the likelihood of a wrong version being selected by an implementation/implementer, or use the [IG Parameter `pin-canonicals`](https://hl7.org/fhir/tools/CodeSystem-ig-parameters.html). Using version '5.0.0', found versions: 2.9.0 (from hl7.terminology.r4#5.0.0), 4.0.0 (from hl7.terminology.r4#6.1.0), 5.0.0 (from hl7.terminology.r4#7.0.1). Suggested fix: change the canonical reference from 'http://terminology.hl7.org/CodeSystem/v2-0203' to 'http://terminology.hl7.org/CodeSystem/v2-0203|5.0.0'"
            },
            "expression": [
              "ValueSet/NWIdentifierType: ValueSet.compose.include[0]"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/ValueSet-OrganisationCheshireAndMerseyside",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ValueSet-OrganisationCheshireAndMerseyside",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              }
            ],
            "severity": "error",
            "code": "exception",
            "details": {
              "text": "Error from https://tx.fhir.org/r4: A definition for CodeSystem 'https://fhir.nhs.uk/Id/ods-organization-code' could not be found, so the value set cannot be expanded"
            },
            "expression": [
              "ValueSet.where(id = 'OrganisationCheshireAndMerseyside')"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/ValueSet-OrganisationGreaterManchester",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ValueSet-OrganisationGreaterManchester",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              }
            ],
            "severity": "error",
            "code": "exception",
            "details": {
              "text": "Error from https://tx.fhir.org/r4: A definition for CodeSystem 'https://fhir.nhs.uk/Id/ods-organization-code' could not be found, so the value set cannot be expanded"
            },
            "expression": [
              "ValueSet.where(id = 'OrganisationGreaterManchester')"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/ValueSet-OrganisationLancashireAndSouthCumbria",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ValueSet-OrganisationLancashireAndSouthCumbria",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              }
            ],
            "severity": "error",
            "code": "exception",
            "details": {
              "text": "Error from https://tx.fhir.org/r4: A definition for CodeSystem 'https://fhir.nhs.uk/Id/ods-organization-code' could not be found, so the value set cannot be expanded"
            },
            "expression": [
              "ValueSet.where(id = 'OrganisationLancashireAndSouthCumbria')"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/ValueSet-OrganisationNorthWest",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ValueSet-OrganisationNorthWest",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              }
            ],
            "severity": "error",
            "code": "exception",
            "details": {
              "text": "Error from https://tx.fhir.org/r4: A definition for CodeSystem 'https://fhir.nhs.uk/Id/ods-organization-code' could not be found, so the value set cannot be expanded"
            },
            "expression": [
              "ValueSet.where(id = 'OrganisationNorthWest')"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/ValueSet-PatientEncounterTriggers",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ValueSet-PatientEncounterTriggers",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 4551
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "There are multiple different potential matches for the url 'http://terminology.hl7.org/CodeSystem/v2-0003'. It might be a good idea to fix to the correct version to reduce the likelihood of a wrong version being selected by an implementation/implementer, or use the [IG Parameter `pin-canonicals`](https://hl7.org/fhir/tools/CodeSystem-ig-parameters.html). Using version '3.0.0', found versions: 2.13.0 (from hl7.terminology.r4#6.1.0), 3.0.0 (from hl7.terminology.r4#7.0.1). Suggested fix: change the canonical reference from 'http://terminology.hl7.org/CodeSystem/v2-0003' to 'http://terminology.hl7.org/CodeSystem/v2-0003|3.0.0'"
            },
            "expression": [
              "ValueSet/PatientEncounterTriggers: ValueSet.compose.include[0]"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/ValueSet-PatientIdentityTriggers",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ValueSet-PatientIdentityTriggers",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 2159
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "There are multiple different potential matches for the url 'http://terminology.hl7.org/CodeSystem/v2-0003'. It might be a good idea to fix to the correct version to reduce the likelihood of a wrong version being selected by an implementation/implementer, or use the [IG Parameter `pin-canonicals`](https://hl7.org/fhir/tools/CodeSystem-ig-parameters.html). Using version '3.0.0', found versions: 2.13.0 (from hl7.terminology.r4#6.1.0), 3.0.0 (from hl7.terminology.r4#7.0.1). Suggested fix: change the canonical reference from 'http://terminology.hl7.org/CodeSystem/v2-0003' to 'http://terminology.hl7.org/CodeSystem/v2-0003|3.0.0'"
            },
            "expression": [
              "ValueSet/PatientIdentityTriggers: ValueSet.compose.include[0]"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/ValueSet-PractitionerIdentifiers",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ValueSet-PractitionerIdentifiers"
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/ValueSet-Pregnancy",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ValueSet-Pregnancy"
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/ValueSet-RequestPriority",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ValueSet-RequestPriority"
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/ValueSet-UKNationalHealthIdentifiers",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ValueSet-UKNationalHealthIdentifiers"
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/ValueSet-YN",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ValueSet-YN"
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/ValueSet-YNU",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ValueSet-YNU"
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/ValueSet-admission-method",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ValueSet-admission-method"
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/ValueSet-admission-source",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ValueSet-admission-source"
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/ValueSet-discharge-destination",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ValueSet-discharge-destination"
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/ValueSet-discharge-disposition",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ValueSet-discharge-disposition"
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/ValueSet-document-entry-class",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ValueSet-document-entry-class"
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/ValueSet-document-entry-mimetype",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ValueSet-document-entry-mimetype"
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/ValueSet-document-entry-type",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ValueSet-document-entry-type",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 22528
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "INACTIVE_CONCEPT_FOUND"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The concept '823881000000104' has a status of inactive and its use should be reviewed"
            },
            "expression": [
              "ValueSet/document-entry-type: ValueSet.compose.include[0].concept[90]"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/ValueSet-ethnicity",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ValueSet-ethnicity"
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/ValueSet-facility-type",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ValueSet-facility-type"
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/ValueSet-order-category",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ValueSet-order-category"
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/ValueSet-service",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ValueSet-service"
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/ValueSet-specialty",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ValueSet-specialty"
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/ValueSet-specimen-tracking-events",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ValueSet-specimen-tracking-events",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 5597
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "There are multiple different potential matches for the url 'http://terminology.hl7.org/CodeSystem/v2-0003'. It might be a good idea to fix to the correct version to reduce the likelihood of a wrong version being selected by an implementation/implementer, or use the [IG Parameter `pin-canonicals`](https://hl7.org/fhir/tools/CodeSystem-ig-parameters.html). Using version '3.0.0', found versions: 2.13.0 (from hl7.terminology.r4#6.1.0), 3.0.0 (from hl7.terminology.r4#7.0.1). Suggested fix: change the canonical reference from 'http://terminology.hl7.org/CodeSystem/v2-0003' to 'http://terminology.hl7.org/CodeSystem/v2-0003|3.0.0'"
            },
            "expression": [
              "ValueSet/specimen-tracking-events: ValueSet.compose.include[0]"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/ValueSet-specimen-type",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ValueSet-specimen-type",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 6323
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '3040001000004100' is not valid in the system http://snomed.info/sct (Unknown code '3040001000004100' in the CodeSystem 'http://snomed.info/sct' version 'http://snomed.info/sct/83821000000107/version/20230412' (UK Edition))"
            },
            "expression": [
              "ValueSet/specimen-type: ValueSet.compose.include[0].concept[16]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 6671
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '16214131000119100' is not valid in the system http://snomed.info/sct (Unknown code '16214131000119100' in the CodeSystem 'http://snomed.info/sct' version 'http://snomed.info/sct/83821000000107/version/20230412' (UK Edition))"
            },
            "expression": [
              "ValueSet/specimen-type: ValueSet.compose.include[0].concept[22]"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/Binary-837d78a0-30cd-478c-83a8-f83d16fc4443",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Binary-837d78a0-30cd-478c-83a8-f83d16fc4443"
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/Bundle-748683741",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Bundle-748683741",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 10
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 64
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https//fhir.mft.nhs.uk/Endpoint/iGene'"
            },
            "expression": [
              "Bundle/748683741: Bundle.entry[0].resource/*MessageHeader/null*/.destination[0].endpoint"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 71
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 56
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://nw-gmsa.github.io/Id/MR'"
            },
            "expression": [
              "Bundle/748683741: Bundle.entry[1].resource/*Patient/null*/.identifier[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 118
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "All_observations_should_have_a_performer"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Best Practice Recommendation: In general, all observations should have a performer"
            },
            "expression": [
              "Bundle/748683741: Bundle.entry[3].resource/*Observation/null*/"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 138
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 77
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://fhir.nwgenomics.nhs.uk/Id/ResourceIdentifier'"
            },
            "expression": [
              "Bundle/748683741: Bundle.entry[3].resource/*Observation/null*/.identifier[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 120
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "UNKNOWN_CODE_IN_FRAGMENT"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "Unknown Code '230056' in the CodeSystem 'https://fhir.nwgenomics.nhs.uk/CodeSystem/MFTQuestionIds' version '0.1.0' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"
            },
            "expression": [
              "Bundle/748683741: Bundle.entry[3].resource/*Observation/null*/.code.coding[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 151
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "All_observations_should_have_a_performer"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Best Practice Recommendation: In general, all observations should have a performer"
            },
            "expression": [
              "Bundle/748683741: Bundle.entry[4].resource/*Observation/null*/"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 171
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 77
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://fhir.nwgenomics.nhs.uk/Id/ResourceIdentifier'"
            },
            "expression": [
              "Bundle/748683741: Bundle.entry[4].resource/*Observation/null*/.identifier[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 153
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "UNKNOWN_CODE_IN_FRAGMENT"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "Unknown Code '230048' in the CodeSystem 'https://fhir.nwgenomics.nhs.uk/CodeSystem/MFTQuestionIds' version '0.1.0' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"
            },
            "expression": [
              "Bundle/748683741: Bundle.entry[4].resource/*Observation/null*/.code.coding[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 184
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "All_observations_should_have_a_performer"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Best Practice Recommendation: In general, all observations should have a performer"
            },
            "expression": [
              "Bundle/748683741: Bundle.entry[5].resource/*Observation/null*/"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 204
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 77
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://fhir.nwgenomics.nhs.uk/Id/ResourceIdentifier'"
            },
            "expression": [
              "Bundle/748683741: Bundle.entry[5].resource/*Observation/null*/.identifier[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 186
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "UNKNOWN_CODE_IN_FRAGMENT"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "Unknown Code '231610' in the CodeSystem 'https://fhir.nwgenomics.nhs.uk/CodeSystem/MFTQuestionIds' version '0.1.0' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"
            },
            "expression": [
              "Bundle/748683741: Bundle.entry[5].resource/*Observation/null*/.code.coding[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 217
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "All_observations_should_have_a_performer"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Best Practice Recommendation: In general, all observations should have a performer"
            },
            "expression": [
              "Bundle/748683741: Bundle.entry[6].resource/*Observation/null*/"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 237
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 77
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://fhir.nwgenomics.nhs.uk/Id/ResourceIdentifier'"
            },
            "expression": [
              "Bundle/748683741: Bundle.entry[6].resource/*Observation/null*/.identifier[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 219
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "UNKNOWN_CODE_IN_FRAGMENT"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "Unknown Code '230030' in the CodeSystem 'https://fhir.nwgenomics.nhs.uk/CodeSystem/MFTQuestionIds' version '0.1.0' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"
            },
            "expression": [
              "Bundle/748683741: Bundle.entry[6].resource/*Observation/null*/.code.coding[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 250
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "All_observations_should_have_a_performer"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Best Practice Recommendation: In general, all observations should have a performer"
            },
            "expression": [
              "Bundle/748683741: Bundle.entry[7].resource/*Observation/null*/"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 270
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 77
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://fhir.nwgenomics.nhs.uk/Id/ResourceIdentifier'"
            },
            "expression": [
              "Bundle/748683741: Bundle.entry[7].resource/*Observation/null*/.identifier[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 252
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "UNKNOWN_CODE_IN_FRAGMENT"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "Unknown Code '230038' in the CodeSystem 'https://fhir.nwgenomics.nhs.uk/CodeSystem/MFTQuestionIds' version '0.1.0' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"
            },
            "expression": [
              "Bundle/748683741: Bundle.entry[7].resource/*Observation/null*/.code.coding[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 283
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "All_observations_should_have_a_performer"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Best Practice Recommendation: In general, all observations should have a performer"
            },
            "expression": [
              "Bundle/748683741: Bundle.entry[8].resource/*Observation/null*/"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 303
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 77
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://fhir.nwgenomics.nhs.uk/Id/ResourceIdentifier'"
            },
            "expression": [
              "Bundle/748683741: Bundle.entry[8].resource/*Observation/null*/.identifier[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 285
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "UNKNOWN_CODE_IN_FRAGMENT"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "Unknown Code '230027' in the CodeSystem 'https://fhir.nwgenomics.nhs.uk/CodeSystem/MFTQuestionIds' version '0.1.0' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"
            },
            "expression": [
              "Bundle/748683741: Bundle.entry[8].resource/*Observation/null*/.code.coding[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 316
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "All_observations_should_have_a_performer"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Best Practice Recommendation: In general, all observations should have a performer"
            },
            "expression": [
              "Bundle/748683741: Bundle.entry[9].resource/*Observation/null*/"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 336
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 77
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://fhir.nwgenomics.nhs.uk/Id/ResourceIdentifier'"
            },
            "expression": [
              "Bundle/748683741: Bundle.entry[9].resource/*Observation/null*/.identifier[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 318
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "UNKNOWN_CODE_IN_FRAGMENT"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "Unknown Code '230029' in the CodeSystem 'https://fhir.nwgenomics.nhs.uk/CodeSystem/MFTQuestionIds' version '0.1.0' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"
            },
            "expression": [
              "Bundle/748683741: Bundle.entry[9].resource/*Observation/null*/.code.coding[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 349
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "All_observations_should_have_a_performer"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Best Practice Recommendation: In general, all observations should have a performer"
            },
            "expression": [
              "Bundle/748683741: Bundle.entry[10].resource/*Observation/null*/"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 369
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 77
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://fhir.nwgenomics.nhs.uk/Id/ResourceIdentifier'"
            },
            "expression": [
              "Bundle/748683741: Bundle.entry[10].resource/*Observation/null*/.identifier[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 351
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "UNKNOWN_CODE_IN_FRAGMENT"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "Unknown Code '230037' in the CodeSystem 'https://fhir.nwgenomics.nhs.uk/CodeSystem/MFTQuestionIds' version '0.1.0' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"
            },
            "expression": [
              "Bundle/748683741: Bundle.entry[10].resource/*Observation/null*/.code.coding[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 382
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "All_observations_should_have_a_performer"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Best Practice Recommendation: In general, all observations should have a performer"
            },
            "expression": [
              "Bundle/748683741: Bundle.entry[11].resource/*Observation/null*/"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 402
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 77
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://fhir.nwgenomics.nhs.uk/Id/ResourceIdentifier'"
            },
            "expression": [
              "Bundle/748683741: Bundle.entry[11].resource/*Observation/null*/.identifier[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 384
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "UNKNOWN_CODE_IN_FRAGMENT"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "Unknown Code '230039' in the CodeSystem 'https://fhir.nwgenomics.nhs.uk/CodeSystem/MFTQuestionIds' version '0.1.0' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"
            },
            "expression": [
              "Bundle/748683741: Bundle.entry[11].resource/*Observation/null*/.code.coding[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 415
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "All_observations_should_have_a_performer"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Best Practice Recommendation: In general, all observations should have a performer"
            },
            "expression": [
              "Bundle/748683741: Bundle.entry[12].resource/*Observation/null*/"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 435
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 77
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://fhir.nwgenomics.nhs.uk/Id/ResourceIdentifier'"
            },
            "expression": [
              "Bundle/748683741: Bundle.entry[12].resource/*Observation/null*/.identifier[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 417
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "UNKNOWN_CODE_IN_FRAGMENT"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "Unknown Code '230049' in the CodeSystem 'https://fhir.nwgenomics.nhs.uk/CodeSystem/MFTQuestionIds' version '0.1.0' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"
            },
            "expression": [
              "Bundle/748683741: Bundle.entry[12].resource/*Observation/null*/.code.coding[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 448
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "All_observations_should_have_a_performer"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Best Practice Recommendation: In general, all observations should have a performer"
            },
            "expression": [
              "Bundle/748683741: Bundle.entry[13].resource/*Observation/null*/"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 448
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "All_observations_should_have_an_effectiveDateTime_or_an_effectivePeriod"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Best Practice Recommendation: In general, all observations should have an effective[x] ()"
            },
            "expression": [
              "Bundle/748683741: Bundle.entry[13].resource/*Observation/null*/"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 466
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 77
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://fhir.nwgenomics.nhs.uk/Id/ResourceIdentifier'"
            },
            "expression": [
              "Bundle/748683741: Bundle.entry[13].resource/*Observation/null*/.identifier[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 450
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Coding_has_no_system__cannot_validate"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Coding has no system. A code with no system has no defined meaning, and it cannot be validated. A system should be provided"
            },
            "expression": [
              "Bundle/748683741: Bundle.entry[13].resource/*Observation/null*/.code.coding[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 485
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Coding_has_no_system__cannot_validate"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Coding has no system. A code with no system has no defined meaning, and it cannot be validated. A system should be provided"
            },
            "expression": [
              "Bundle/748683741: Bundle.entry[14].resource/*Specimen/null*/.type.coding[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 525
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 58
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://nw-gmsa.github.io/Id/PLAC'"
            },
            "expression": [
              "Bundle/748683741: Bundle.entry[15].resource/*ServiceRequest/null*/.identifier[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 548
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 56
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://nw-gmsa.github.io/Id/PLAC'"
            },
            "expression": [
              "Bundle/748683741: Bundle.entry[15].resource/*ServiceRequest/null*/.requisition.system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 509
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "UNKNOWN_CODE_IN_FRAGMENT"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "Unknown Code 'M213.22' in the CodeSystem 'https://fhir.nhs.uk/CodeSystem/England-GenomicTestDirectory' version '0.1.0' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"
            },
            "expression": [
              "Bundle/748683741: Bundle.entry[15].resource/*ServiceRequest/null*/.code.coding[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 648
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 58
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://nw-gmsa.github.io/Id/PLAC'"
            },
            "expression": [
              "Bundle/748683741: Bundle.entry[16].resource/*ServiceRequest/null*/.identifier[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 671
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 56
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://nw-gmsa.github.io/Id/PLAC'"
            },
            "expression": [
              "Bundle/748683741: Bundle.entry[16].resource/*ServiceRequest/null*/.requisition.system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 632
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "UNKNOWN_CODE_IN_FRAGMENT"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "Unknown Code 'M213.13' in the CodeSystem 'https://fhir.nhs.uk/CodeSystem/England-GenomicTestDirectory' version '0.1.0' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"
            },
            "expression": [
              "Bundle/748683741: Bundle.entry[16].resource/*ServiceRequest/null*/.code.coding[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 725
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 58
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://nw-gmsa.github.io/Id/PLAC'"
            },
            "expression": [
              "Bundle/748683741: Bundle.entry[17].resource/*ServiceRequest/null*/.identifier[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 748
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 56
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://nw-gmsa.github.io/Id/PLAC'"
            },
            "expression": [
              "Bundle/748683741: Bundle.entry[17].resource/*ServiceRequest/null*/.requisition.system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 709
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "UNKNOWN_CODE_IN_FRAGMENT"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "Unknown Code 'M213.23' in the CodeSystem 'https://fhir.nhs.uk/CodeSystem/England-GenomicTestDirectory' version '0.1.0' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"
            },
            "expression": [
              "Bundle/748683741: Bundle.entry[17].resource/*ServiceRequest/null*/.code.coding[0].code"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/Bundle-Bundle-NonWGSTestOrderForm-CancerSolidTumor-Example",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Bundle-Bundle-NonWGSTestOrderForm-CancerSolidTumor-Example",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 4
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 4
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TYPE_SPECIFIC_CHECKS_DT_IDENTIFIER_IETF_SYSTEM_WRONG_2"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "The URL 'https://tools.ietf.org/html/rfc4122' should not be used with the UUID '156bb6ab-15e7-42f3-a819-ecd16a5b4fbd'. Prefix the value with 'urn:uuid:' and use the system value 'urn:ietf:rfc:3986' instead"
            },
            "expression": [
              "Bundle/Bundle-NonWGSTestOrderForm-CancerSolidTumor-Example: Bundle.identifier"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 64
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 59
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://fhir.nhs.uk/Id/sds-user-id'"
            },
            "expression": [
              "Bundle/Bundle-NonWGSTestOrderForm-CancerSolidTumor-Example: Bundle.entry[1].resource/*PractitionerRole/null*/.practitioner.identifier.system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 125
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 59
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://fhir.nhs.uk/Id/sds-user-id'"
            },
            "expression": [
              "Bundle/Bundle-NonWGSTestOrderForm-CancerSolidTumor-Example: Bundle.entry[2].resource/*PractitionerRole/null*/.practitioner.identifier.system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 182
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 59
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://fhir.nhs.uk/Id/sds-user-id'"
            },
            "expression": [
              "Bundle/Bundle-NonWGSTestOrderForm-CancerSolidTumor-Example: Bundle.entry[3].resource/*PractitionerRole/null*/.practitioner.identifier.system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 268
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 16
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Extension_EXT_Unknown_NotHere"
              }
            ],
            "severity": "error",
            "code": "structure",
            "details": {
              "text": "The extension https://fhir.hl7.org.uk/StructureDefinition/Extension-UKCore-NHSIdentifierVerificationStatus could not be found so is not allowed here"
            },
            "expression": [
              "Bundle/Bundle-NonWGSTestOrderForm-CancerSolidTumor-Example: Bundle.entry[4].resource/*Patient/null*/.identifier[0].extension[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 269
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 118
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://fhir.hl7.org.uk/StructureDefinition/Extension-UKCore-NHSIdentifierVerificationStatus'"
            },
            "expression": [
              "Bundle/Bundle-NonWGSTestOrderForm-CancerSolidTumor-Example: Bundle.entry[4].resource/*Patient/null*/.identifier[0].extension[0].url"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 270
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 18
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "UNKNOWN_CODESYSTEM_VERSION_NONE"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'https://fhir.hl7.org.uk/CodeSystem/UKCore-NHSIdentifierVerificationStatusEngland' version '2.2.0' could not be found, so the code cannot be validated. No versions of this code system are known"
            },
            "expression": [
              "Bundle/Bundle-NonWGSTestOrderForm-CancerSolidTumor-Example: Bundle.entry[4].resource/*Patient/null*/.identifier[0].extension[0].value.ofType(CodeableConcept).coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 324
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 62
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://fhir.hl7.org.uk/Id/ODS-code'"
            },
            "expression": [
              "Bundle/Bundle-NonWGSTestOrderForm-CancerSolidTumor-Example: Bundle.entry[4].resource/*Patient/null*/.generalPractitioner[1].identifier.system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 332
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 14
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Reference_REF_CantResolve"
              }
            ],
            "severity": "error",
            "code": "structure",
            "details": {
              "text": "Unable to resolve resource with reference 'https://api.service.nhs.uk/personal-demographics/FHIR/R4/Patient/9449307555'"
            },
            "expression": [
              "Bundle/Bundle-NonWGSTestOrderForm-CancerSolidTumor-Example: Bundle.entry[4].resource/*Patient/null*/.link[0].other"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 342
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "All_observations_should_have_a_performer"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Best Practice Recommendation: In general, all observations should have a performer"
            },
            "expression": [
              "Bundle/Bundle-NonWGSTestOrderForm-CancerSolidTumor-Example: Bundle.entry[5].resource/*Observation/null*/"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 364
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 62
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://fhir.add.nhs.uk/Id/specimenId'"
            },
            "expression": [
              "Bundle/Bundle-NonWGSTestOrderForm-CancerSolidTumor-Example: Bundle.entry[5].resource/*Observation/null*/.specimen.identifier.system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 393
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "All_observations_should_have_a_performer"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Best Practice Recommendation: In general, all observations should have a performer"
            },
            "expression": [
              "Bundle/Bundle-NonWGSTestOrderForm-CancerSolidTumor-Example: Bundle.entry[6].resource/*Observation/null*/"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 414
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 62
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://fhir.add.nhs.uk/Id/specimenId'"
            },
            "expression": [
              "Bundle/Bundle-NonWGSTestOrderForm-CancerSolidTumor-Example: Bundle.entry[6].resource/*Observation/null*/.specimen.identifier.system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 522
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "UNKNOWN_CODESYSTEM_VERSION"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'https://fhir.nhs.uk/CodeSystem/England-GenomicTestDirectory' version '9' could not be found, so the code cannot be validated. Valid versions: 0.1.0"
            },
            "expression": [
              "Bundle/Bundle-NonWGSTestOrderForm-CancerSolidTumor-Example: Bundle.entry[8].resource/*ServiceRequest/null*/.code.coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 544
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 12
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "UNKNOWN_CODESYSTEM"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'https://fhir.nhs.uk/CodeSystem/reasonfortesting-genomics' could not be found, so the code cannot be validated"
            },
            "expression": [
              "Bundle/Bundle-NonWGSTestOrderForm-CancerSolidTumor-Example: Bundle.entry[8].resource/*ServiceRequest/null*/.reasonCode[0].coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 592
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 62
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://fhir.add.nhs.uk/Id/specimenId'"
            },
            "expression": [
              "Bundle/Bundle-NonWGSTestOrderForm-CancerSolidTumor-Example: Bundle.entry[9].resource/*Specimen/null*/.identifier[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 616
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 61
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://fhir.nhs.uk/Id/sds-user-id'"
            },
            "expression": [
              "Bundle/Bundle-NonWGSTestOrderForm-CancerSolidTumor-Example: Bundle.entry[9].resource/*Specimen/null*/.collection.collector.identifier.system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/Bundle-Bundle-NonWGSTestOrderForm-FetalScenario-Example",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Bundle-Bundle-NonWGSTestOrderForm-FetalScenario-Example",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 4
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 4
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TYPE_SPECIFIC_CHECKS_DT_IDENTIFIER_IETF_SYSTEM_WRONG_2"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "The URL 'https://tools.ietf.org/html/rfc4122' should not be used with the UUID 'b9df1c3a-2335-4ddc-a901-e0a0a44d9c19'. Prefix the value with 'urn:uuid:' and use the system value 'urn:ietf:rfc:3986' instead"
            },
            "expression": [
              "Bundle/Bundle-NonWGSTestOrderForm-FetalScenario-Example: Bundle.identifier"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 65
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 59
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://fhir.nhs.uk/Id/sds-user-id'"
            },
            "expression": [
              "Bundle/Bundle-NonWGSTestOrderForm-FetalScenario-Example: Bundle.entry[1].resource/*PractitionerRole/PractitionerRole-LoisLaneKingstonClinicalGenetics-Example*/.practitioner.identifier.system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 166
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 16
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Extension_EXT_Unknown_NotHere"
              }
            ],
            "severity": "error",
            "code": "structure",
            "details": {
              "text": "The extension https://fhir.hl7.org.uk/StructureDefinition/Extension-UKCore-NHSIdentifierVerificationStatus could not be found so is not allowed here"
            },
            "expression": [
              "Bundle/Bundle-NonWGSTestOrderForm-FetalScenario-Example: Bundle.entry[2].resource/*Patient/Patient-RyanneBoulder-Example*/.identifier[0].extension[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 167
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 118
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://fhir.hl7.org.uk/StructureDefinition/Extension-UKCore-NHSIdentifierVerificationStatus'"
            },
            "expression": [
              "Bundle/Bundle-NonWGSTestOrderForm-FetalScenario-Example: Bundle.entry[2].resource/*Patient/Patient-RyanneBoulder-Example*/.identifier[0].extension[0].url"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 168
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 18
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "UNKNOWN_CODESYSTEM_VERSION_NONE"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'https://fhir.hl7.org.uk/CodeSystem/UKCore-NHSIdentifierVerificationStatusEngland' version '2.2.0' could not be found, so the code cannot be validated. No versions of this code system are known"
            },
            "expression": [
              "Bundle/Bundle-NonWGSTestOrderForm-FetalScenario-Example: Bundle.entry[2].resource/*Patient/Patient-RyanneBoulder-Example*/.identifier[0].extension[0].value.ofType(CodeableConcept).coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 222
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 62
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://fhir.hl7.org.uk/Id/ODS-code'"
            },
            "expression": [
              "Bundle/Bundle-NonWGSTestOrderForm-FetalScenario-Example: Bundle.entry[2].resource/*Patient/Patient-RyanneBoulder-Example*/.generalPractitioner[1].identifier.system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 230
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 14
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Reference_REF_CantResolve"
              }
            ],
            "severity": "error",
            "code": "structure",
            "details": {
              "text": "Unable to resolve resource with reference 'https://api.service.nhs.uk/personal-demographics/FHIR/R4/Patient/9449307687'"
            },
            "expression": [
              "Bundle/Bundle-NonWGSTestOrderForm-FetalScenario-Example: Bundle.entry[2].resource/*Patient/Patient-RyanneBoulder-Example*/.link[0].other"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 294
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "All_observations_should_have_a_performer"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Best Practice Recommendation: In general, all observations should have a performer"
            },
            "expression": [
              "Bundle/Bundle-NonWGSTestOrderForm-FetalScenario-Example: Bundle.entry[5].resource/*Observation/Observation-GenomicEthnicity-Example*/"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 294
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "All_observations_should_have_an_effectiveDateTime_or_an_effectivePeriod"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Best Practice Recommendation: In general, all observations should have an effective[x] ()"
            },
            "expression": [
              "Bundle/Bundle-NonWGSTestOrderForm-FetalScenario-Example: Bundle.entry[5].resource/*Observation/Observation-GenomicEthnicity-Example*/"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 350
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "UNKNOWN_CODESYSTEM_VERSION"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'https://fhir.nhs.uk/CodeSystem/England-GenomicTestDirectory' version '7' could not be found, so the code cannot be validated. Valid versions: 0.1.0"
            },
            "expression": [
              "Bundle/Bundle-NonWGSTestOrderForm-FetalScenario-Example: Bundle.entry[6].resource/*ServiceRequest/ServiceRequest-NonWGSTestOrderForm-FetalScenario-Example*/.code.coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 378
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 12
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'https://fhir.nhs.uk/CodeSystem/reasonfortesting-genomics' could not be found, so the code cannot be validated"
            },
            "expression": [
              "Bundle/Bundle-NonWGSTestOrderForm-FetalScenario-Example: Bundle.entry[6].resource/*ServiceRequest/ServiceRequest-NonWGSTestOrderForm-FetalScenario-Example*/.reasonCode[0].coding[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 447
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "All_observations_should_have_a_performer"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Best Practice Recommendation: In general, all observations should have a performer"
            },
            "expression": [
              "Bundle/Bundle-NonWGSTestOrderForm-FetalScenario-Example: Bundle.entry[7].resource/*Observation/Observation-HistoryOfFetalLoss-Example*/"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 451
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Display_Name_for__should_be_one_of__instead_of"
              }
            ],
            "severity": "error",
            "code": "invalid",
            "details": {
              "text": "Wrong Display Name 'Past pregnancy history of stillbirth (situation)' for http://snomed.info/sct#161743003. Valid display is 'H/O: stillbirth' (en) (for the language(s) 'en-GB')"
            },
            "expression": [
              "Bundle/Bundle-NonWGSTestOrderForm-FetalScenario-Example: Bundle.entry[7].resource/*Observation/Observation-HistoryOfFetalLoss-Example*/.code.coding[0].display"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 474
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "All_observations_should_have_a_performer"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Best Practice Recommendation: In general, all observations should have a performer"
            },
            "expression": [
              "Bundle/Bundle-NonWGSTestOrderForm-FetalScenario-Example: Bundle.entry[8].resource/*Observation/Observation-PregnancyConfirmation-Example*/"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 541
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "All_observations_should_have_a_performer"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Best Practice Recommendation: In general, all observations should have a performer"
            },
            "expression": [
              "Bundle/Bundle-NonWGSTestOrderForm-FetalScenario-Example: Bundle.entry[9].resource/*Observation/Observation-NonConsanguinousUnion-Example*/"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 575
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "All_observations_should_have_a_performer"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Best Practice Recommendation: In general, all observations should have a performer"
            },
            "expression": [
              "Bundle/Bundle-NonWGSTestOrderForm-FetalScenario-Example: Bundle.entry[10].resource/*Observation/Observation-NoTransplant-Example*/"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 609
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "All_observations_should_have_a_performer"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Best Practice Recommendation: In general, all observations should have a performer"
            },
            "expression": [
              "Bundle/Bundle-NonWGSTestOrderForm-FetalScenario-Example: Bundle.entry[11].resource/*Observation/Observation-NoFirstTrimesterFetalAnomalies-Example*/"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 649
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "All_observations_should_have_a_performer"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Best Practice Recommendation: In general, all observations should have a performer"
            },
            "expression": [
              "Bundle/Bundle-NonWGSTestOrderForm-FetalScenario-Example: Bundle.entry[12].resource/*Observation/Observation-NoSecondTrimesterFetalAnomalies-Example*/"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 723
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 75
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://fhir.kingstonhospital.nhs.uk/Id/specimenId'"
            },
            "expression": [
              "Bundle/Bundle-NonWGSTestOrderForm-FetalScenario-Example: Bundle.entry[14].resource/*Specimen/Specimen-BloodEDTA-Example*/.identifier[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 758
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 75
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://fhir.kingstonhospital.nhs.uk/Id/specimenId'"
            },
            "expression": [
              "Bundle/Bundle-NonWGSTestOrderForm-FetalScenario-Example: Bundle.entry[15].resource/*Specimen/Specimen-RyanneBoulderSaliva-Example*/.identifier[0].system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/Bundle-Bundle-NonWGSTestOrderForm-Reanalysis-Example",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Bundle-Bundle-NonWGSTestOrderForm-Reanalysis-Example",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 4
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 6
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TYPE_SPECIFIC_CHECKS_DT_IDENTIFIER_IETF_SYSTEM_WRONG_2"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "The URL 'https://tools.ietf.org/html/rfc4122' should not be used with the UUID '9ba09056-0ee6-452d-8fa7-fce9181b13cb'. Prefix the value with 'urn:uuid:' and use the system value 'urn:ietf:rfc:3986' instead"
            },
            "expression": [
              "Bundle/Bundle-NonWGSTestOrderForm-Reanalysis-Example: Bundle.identifier"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 65
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 71
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://fhir.nhs.uk/Id/sds-user-id'"
            },
            "expression": [
              "Bundle/Bundle-NonWGSTestOrderForm-Reanalysis-Example: Bundle.entry[1].resource/*PractitionerRole/PractitionerRole-HazelSmithRenal-Example*/.practitioner.identifier.system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 156
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 30
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Extension_EXT_Unknown_NotHere"
              }
            ],
            "severity": "error",
            "code": "structure",
            "details": {
              "text": "The extension https://fhir.hl7.org.uk/StructureDefinition/Extension-UKCore-NHSIdentifierVerificationStatus could not be found so is not allowed here"
            },
            "expression": [
              "Bundle/Bundle-NonWGSTestOrderForm-Reanalysis-Example: Bundle.entry[2].resource/*Patient/Patient-DemeizaSeo-Example*/.identifier[0].extension[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 157
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 134
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://fhir.hl7.org.uk/StructureDefinition/Extension-UKCore-NHSIdentifierVerificationStatus'"
            },
            "expression": [
              "Bundle/Bundle-NonWGSTestOrderForm-Reanalysis-Example: Bundle.entry[2].resource/*Patient/Patient-DemeizaSeo-Example*/.identifier[0].extension[0].url"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 158
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 34
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "UNKNOWN_CODESYSTEM_VERSION_NONE"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'https://fhir.hl7.org.uk/CodeSystem/UKCore-NHSIdentifierVerificationStatusEngland' version '2.2.0' could not be found, so the code cannot be validated. No versions of this code system are known"
            },
            "expression": [
              "Bundle/Bundle-NonWGSTestOrderForm-Reanalysis-Example: Bundle.entry[2].resource/*Patient/Patient-DemeizaSeo-Example*/.identifier[0].extension[0].value.ofType(CodeableConcept).coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 172
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 78
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'urn:oid:2.16.840.1.113883.2.1.3.2.4.18.24'"
            },
            "expression": [
              "Bundle/Bundle-NonWGSTestOrderForm-Reanalysis-Example: Bundle.entry[2].resource/*Patient/Patient-DemeizaSeo-Example*/.identifier[1].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 212
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 76
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://fhir.hl7.org.uk/Id/ODS-code'"
            },
            "expression": [
              "Bundle/Bundle-NonWGSTestOrderForm-Reanalysis-Example: Bundle.entry[2].resource/*Patient/Patient-DemeizaSeo-Example*/.generalPractitioner[1].identifier.system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 220
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 26
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Reference_REF_CantResolve"
              }
            ],
            "severity": "error",
            "code": "structure",
            "details": {
              "text": "Unable to resolve resource with reference 'https://api.service.nhs.uk/personal-demographics/FHIR/R4/Patient/9449307559'"
            },
            "expression": [
              "Bundle/Bundle-NonWGSTestOrderForm-Reanalysis-Example: Bundle.entry[2].resource/*Patient/Patient-DemeizaSeo-Example*/.link[0].other"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 230
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 14
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "All_observations_should_have_a_performer"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Best Practice Recommendation: In general, all observations should have a performer"
            },
            "expression": [
              "Bundle/Bundle-NonWGSTestOrderForm-Reanalysis-Example: Bundle.entry[3].resource/*Observation/Observation-GenomicEthnicity-Example*/"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 230
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 14
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "All_observations_should_have_an_effectiveDateTime_or_an_effectivePeriod"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Best Practice Recommendation: In general, all observations should have an effective[x] ()"
            },
            "expression": [
              "Bundle/Bundle-NonWGSTestOrderForm-Reanalysis-Example: Bundle.entry[3].resource/*Observation/Observation-GenomicEthnicity-Example*/"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Bundle_BUNDLE_Not_Local"
              }
            ],
            "severity": "warning",
            "code": "required",
            "details": {
              "text": "URN reference is not locally contained within the bundle urn:uuid:943f3dbb-6904-46ee-acd7-466c1c4b8a06"
            },
            "expression": [
              "Bundle/Bundle-NonWGSTestOrderForm-Reanalysis-Example: Bundle.entry[4].resource/*ServiceRequest/ServiceRequest-NonWGSTestOrderForm-ReAnalysis-Example*/.basedOn[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 259
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 22
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Reference_REF_CantResolve"
              }
            ],
            "severity": "error",
            "code": "structure",
            "details": {
              "text": "Unable to resolve resource with reference 'urn:uuid:943f3dbb-6904-46ee-acd7-466c1c4b8a06'"
            },
            "expression": [
              "Bundle/Bundle-NonWGSTestOrderForm-Reanalysis-Example: Bundle.entry[4].resource/*ServiceRequest/ServiceRequest-NonWGSTestOrderForm-ReAnalysis-Example*/.basedOn[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 290
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 18
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "UNKNOWN_CODESYSTEM_VERSION"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'https://fhir.nhs.uk/CodeSystem/England-GenomicTestDirectory' version '7' could not be found, so the code cannot be validated. Valid versions: 0.1.0"
            },
            "expression": [
              "Bundle/Bundle-NonWGSTestOrderForm-Reanalysis-Example: Bundle.entry[4].resource/*ServiceRequest/ServiceRequest-NonWGSTestOrderForm-ReAnalysis-Example*/.code.coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 301
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 22
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "UNKNOWN_CODESYSTEM_VERSION"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'https://fhir.nhs.uk/CodeSystem/England-GenomicTestDirectory' version '7' could not be found, so the code cannot be validated. Valid versions: 0.1.0"
            },
            "expression": [
              "Bundle/Bundle-NonWGSTestOrderForm-Reanalysis-Example: Bundle.entry[4].resource/*ServiceRequest/ServiceRequest-NonWGSTestOrderForm-ReAnalysis-Example*/.orderDetail[0].coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Bundle_BUNDLE_Not_Local"
              }
            ],
            "severity": "warning",
            "code": "required",
            "details": {
              "text": "URN reference is not locally contained within the bundle urn:uuid:da7edbd3-cc37-4c2d-8bb0-9da528c4695a"
            },
            "expression": [
              "Bundle/Bundle-NonWGSTestOrderForm-Reanalysis-Example: Bundle.entry[4].resource/*ServiceRequest/ServiceRequest-NonWGSTestOrderForm-ReAnalysis-Example*/.requester"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 320
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 18
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Reference_REF_CantResolve"
              }
            ],
            "severity": "error",
            "code": "structure",
            "details": {
              "text": "Unable to resolve resource with reference 'urn:uuid:da7edbd3-cc37-4c2d-8bb0-9da528c4695a'"
            },
            "expression": [
              "Bundle/Bundle-NonWGSTestOrderForm-Reanalysis-Example: Bundle.entry[4].resource/*ServiceRequest/ServiceRequest-NonWGSTestOrderForm-ReAnalysis-Example*/.requester"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 324
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 22
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'https://fhir.nhs.uk/CodeSystem/reasonfortesting-genomics' could not be found, so the code cannot be validated"
            },
            "expression": [
              "Bundle/Bundle-NonWGSTestOrderForm-Reanalysis-Example: Bundle.entry[4].resource/*ServiceRequest/ServiceRequest-NonWGSTestOrderForm-ReAnalysis-Example*/.reasonCode[0].coding[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 372
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 14
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "All_observations_should_have_a_performer"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Best Practice Recommendation: In general, all observations should have a performer"
            },
            "expression": [
              "Bundle/Bundle-NonWGSTestOrderForm-Reanalysis-Example: Bundle.entry[5].resource/*Observation/Observation-NoPregnancy-Example*/"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 418
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 18
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "UNKNOWN_CODESYSTEM_VERSION"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'https://fhir.nhs.uk/CodeSystem/England-GenomicTestDirectory' version '7' could not be found, so the code cannot be validated. Valid versions: 0.1.0"
            },
            "expression": [
              "Bundle/Bundle-NonWGSTestOrderForm-Reanalysis-Example: Bundle.entry[6].resource/*Condition/Condition-MonogenicHearingLoss-Example*/.code.coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 439
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 14
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "All_observations_should_have_a_performer"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Best Practice Recommendation: In general, all observations should have a performer"
            },
            "expression": [
              "Bundle/Bundle-NonWGSTestOrderForm-Reanalysis-Example: Bundle.entry[7].resource/*Observation/Observation-NonConsanguinousUnion-Example*/"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 465
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 14
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "All_observations_should_have_a_performer"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Best Practice Recommendation: In general, all observations should have a performer"
            },
            "expression": [
              "Bundle/Bundle-NonWGSTestOrderForm-Reanalysis-Example: Bundle.entry[8].resource/*Observation/Observation-NoBoneMarrowTransplant-Example*/"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 499
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 14
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "All_observations_should_have_a_performer"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Best Practice Recommendation: In general, all observations should have a performer"
            },
            "expression": [
              "Bundle/Bundle-NonWGSTestOrderForm-Reanalysis-Example: Bundle.entry[9].resource/*Observation/Observation-NoTransfusion-Example*/"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 58
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Bundle_BUNDLE_Entry_Orphan_MESSAGE"
              }
            ],
            "severity": "warning",
            "code": "informational",
            "details": {
              "text": "Entry 'http://example.org/fhir/urn:uuid:da7edbd3-cc37-4c2d-8bb0-9da528c4695a' isn't reachable by traversing links (forward or backward) from the MessageHeader, so its presence should be reviewed (is it needed to process the message?)"
            },
            "expression": [
              "Bundle/Bundle-NonWGSTestOrderForm-Reanalysis-Example: Bundle.entry[2]"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/Questionnaire-58410-2",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Questionnaire-58410-2",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 31782
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Unknown_Code_in_Version"
              }
            ],
            "severity": "error",
            "code": "code-invalid",
            "details": {
              "text": "Unknown code '147071010000102' in the CodeSystem 'http://snomed.info/sct' version 'http://snomed.info/sct/83821000000107/version/20230412' (UK Edition)"
            },
            "expression": [
              "Questionnaire/58410-2: Questionnaire.item[0].code[1].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 32158
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Unknown_Code_in_Version"
              }
            ],
            "severity": "error",
            "code": "code-invalid",
            "details": {
              "text": "Unknown code '249121010000107' in the CodeSystem 'http://snomed.info/sct' version 'http://snomed.info/sct/83821000000107/version/20230412' (UK Edition)"
            },
            "expression": [
              "Questionnaire/58410-2: Questionnaire.item[1].code[1].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 32526
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Unknown_Code_in_Version"
              }
            ],
            "severity": "error",
            "code": "code-invalid",
            "details": {
              "text": "Unknown code '168331010000106' in the CodeSystem 'http://snomed.info/sct' version 'http://snomed.info/sct/83821000000107/version/20230412' (UK Edition)"
            },
            "expression": [
              "Questionnaire/58410-2: Questionnaire.item[2].code[1].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 32892
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Unknown_Code_in_Version"
              }
            ],
            "severity": "error",
            "code": "code-invalid",
            "details": {
              "text": "Unknown code '558261010000109' in the CodeSystem 'http://snomed.info/sct' version 'http://snomed.info/sct/83821000000107/version/20230412' (UK Edition)"
            },
            "expression": [
              "Questionnaire/58410-2: Questionnaire.item[3].code[1].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 33581
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Display_Name_for__should_be_one_of__instead_of"
              }
            ],
            "severity": "error",
            "code": "invalid",
            "details": {
              "text": "Wrong Display Name 'RBC Auto' for http://loinc.org#787-2. Valid display is one of 4 choices: 'MCV [Entitic mean volume] in Red Blood Cells by Automated count' (en-US), 'MCV [Entitic mean volume] in Red Blood Cells by Automated count' (en-US), 'MCV RBC Auto' (en-US) or 'Mean Corpuscular Volume (MCV), Red blood cells' (en-US) (for the language(s) 'en-GB')"
            },
            "expression": [
              "Questionnaire/58410-2: Questionnaire.item[4].code[0].display"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 33642
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Unknown_Code_in_Version"
              }
            ],
            "severity": "error",
            "code": "code-invalid",
            "details": {
              "text": "Unknown code '613061010000108' in the CodeSystem 'http://snomed.info/sct' version 'http://snomed.info/sct/83821000000107/version/20230412' (UK Edition)"
            },
            "expression": [
              "Questionnaire/58410-2: Questionnaire.item[4].code[1].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 34003
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Unknown_Code_in_Version"
              }
            ],
            "severity": "error",
            "code": "code-invalid",
            "details": {
              "text": "Unknown code '612991010000106' in the CodeSystem 'http://snomed.info/sct' version 'http://snomed.info/sct/83821000000107/version/20230412' (UK Edition)"
            },
            "expression": [
              "Questionnaire/58410-2: Questionnaire.item[5].code[1].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 34381
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Unknown_Code_in_Version"
              }
            ],
            "severity": "error",
            "code": "code-invalid",
            "details": {
              "text": "Unknown code '613001010000107' in the CodeSystem 'http://snomed.info/sct' version 'http://snomed.info/sct/83821000000107/version/20230412' (UK Edition)"
            },
            "expression": [
              "Questionnaire/58410-2: Questionnaire.item[6].code[1].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 34689
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Display_Name_for__should_be_one_of__instead_of"
              }
            ],
            "severity": "error",
            "code": "invalid",
            "details": {
              "text": "Wrong Display Name 'RDW RBC Auto' for http://loinc.org#788-0. Valid display is one of 4 choices: 'Erythrocyte [DistWidth] in Blood by Automated count' (en-US), 'Erythrocyte [DistWidth] in Blood by Automated count' (en-US), 'Erythrocyte DistWidth Bld Auto' (en-US) or 'Red Blood Cell (RBC), Blood' (en-US) (for the language(s) 'en-GB')"
            },
            "expression": [
              "Questionnaire/58410-2: Questionnaire.item[7].code[0].display"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 34750
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Unknown_Code_in_Version"
              }
            ],
            "severity": "error",
            "code": "code-invalid",
            "details": {
              "text": "Unknown code '613181010000104' in the CodeSystem 'http://snomed.info/sct' version 'http://snomed.info/sct/83821000000107/version/20230412' (UK Edition)"
            },
            "expression": [
              "Questionnaire/58410-2: Questionnaire.item[7].code[1].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 35479
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Display_Name_for__should_be_one_of__instead_of"
              }
            ],
            "severity": "error",
            "code": "invalid",
            "details": {
              "text": "Wrong Display Name 'RDW RBC Auto' for http://loinc.org#788-0. Valid display is one of 4 choices: 'Erythrocyte [DistWidth] in Blood by Automated count' (en-US), 'Erythrocyte [DistWidth] in Blood by Automated count' (en-US), 'Erythrocyte DistWidth Bld Auto' (en-US) or 'Red Blood Cell (RBC), Blood' (en-US) (for the language(s) 'en-GB')"
            },
            "expression": [
              "Questionnaire/58410-2: Questionnaire.item[8].code[0].display"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 35540
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Unknown_Code_in_Version"
              }
            ],
            "severity": "error",
            "code": "code-invalid",
            "details": {
              "text": "Unknown code '613181010000104' in the CodeSystem 'http://snomed.info/sct' version 'http://snomed.info/sct/83821000000107/version/20230412' (UK Edition)"
            },
            "expression": [
              "Questionnaire/58410-2: Questionnaire.item[8].code[1].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 36349
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Unknown_Code_in_Version"
              }
            ],
            "severity": "error",
            "code": "code-invalid",
            "details": {
              "text": "Unknown code '218801010000106' in the CodeSystem 'http://snomed.info/sct' version 'http://snomed.info/sct/83821000000107/version/20230412' (UK Edition)"
            },
            "expression": [
              "Questionnaire/58410-2: Questionnaire.item[9].code[1].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 37415
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Unknown_Code_in_Version"
              }
            ],
            "severity": "error",
            "code": "code-invalid",
            "details": {
              "text": "Unknown code '528301010000103' in the CodeSystem 'http://snomed.info/sct' version 'http://snomed.info/sct/83821000000107/version/20230412' (UK Edition)"
            },
            "expression": [
              "Questionnaire/58410-2: Questionnaire.item[11].code[1].code"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/Questionnaire-24323-8",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Questionnaire-24323-8",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 54732
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "INACTIVE_CONCEPT_FOUND"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The concept '33914-3' has a status of DISCOURAGED and its use should be reviewed"
            },
            "expression": [
              "Questionnaire/24323-8: Questionnaire.item[4].code[0]"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/DocumentReference-Y05868-d783361d-83fa-438f-977c-601f30ef5ceb",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "DocumentReference-Y05868-d783361d-83fa-438f-977c-601f30ef5ceb",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 20
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 68
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://fhir.nwgenomics.nhs.uk/iGene/ReportNumber'"
            },
            "expression": [
              "DocumentReference/Y05868-d783361d-83fa-438f-977c-601f30ef5ceb: DocumentReference.identifier[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 31
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 4
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Terminology_TX_NoValid_1_CC"
              }
            ],
            "severity": "error",
            "code": "code-invalid",
            "details": {
              "text": "None of the codings provided are in the value set 'DocumentEntry Type' (https://fhir.nwgenomics.nhs.uk/ValueSet/document-entry-type|0.1.0), and a coding from this value set is required) (codes = http://snomed.info/sct#887701000000100)"
            },
            "expression": [
              "DocumentReference/Y05868-d783361d-83fa-438f-977c-601f30ef5ceb: DocumentReference.type"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 83
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Extension_EXT_Unknown_NotHere"
              }
            ],
            "severity": "error",
            "code": "structure",
            "details": {
              "text": "The extension https://fhir.nhs.uk/England/StructureDefinition/Extension-England-ContentStability could not be found so is not allowed here"
            },
            "expression": [
              "DocumentReference/Y05868-d783361d-83fa-438f-977c-601f30ef5ceb: DocumentReference.content[0].extension[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 93
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 102
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://fhir.nhs.uk/England/StructureDefinition/Extension-England-ContentStability'"
            },
            "expression": [
              "DocumentReference/Y05868-d783361d-83fa-438f-977c-601f30ef5ceb: DocumentReference.content[0].extension[0].url"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 84
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 12
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "UNKNOWN_CODESYSTEM"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'https://fhir.nhs.uk/England/CodeSystem/England-NRLContentStability' could not be found, so the code cannot be validated"
            },
            "expression": [
              "DocumentReference/Y05868-d783361d-83fa-438f-977c-601f30ef5ceb: DocumentReference.content[0].extension[0].value.ofType(CodeableConcept).coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 95
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Extension_EXT_Unknown_NotHere"
              }
            ],
            "severity": "error",
            "code": "structure",
            "details": {
              "text": "The extension https://fhir.nhs.uk/England/StructureDefinition/Extension-England-NRLRetrievalMechanism could not be found so is not allowed here"
            },
            "expression": [
              "DocumentReference/Y05868-d783361d-83fa-438f-977c-601f30ef5ceb: DocumentReference.content[0].extension[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 105
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 107
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://fhir.nhs.uk/England/StructureDefinition/Extension-England-NRLRetrievalMechanism'"
            },
            "expression": [
              "DocumentReference/Y05868-d783361d-83fa-438f-977c-601f30ef5ceb: DocumentReference.content[0].extension[1].url"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 96
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 12
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "UNKNOWN_CODESYSTEM"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'https://fhir.nhs.uk/England/CodeSystem/England-NRLRetrievalMechanism' could not be found, so the code cannot be validated"
            },
            "expression": [
              "DocumentReference/Y05868-d783361d-83fa-438f-977c-601f30ef5ceb: DocumentReference.content[0].extension[1].value.ofType(CodeableConcept).coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 113
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "UNKNOWN_CODESYSTEM"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'https://fhir.nhs.uk/England/CodeSystem/England-NRLFormatCode' could not be found, so the code cannot be validated"
            },
            "expression": [
              "DocumentReference/Y05868-d783361d-83fa-438f-977c-601f30ef5ceb: DocumentReference.content[0].format.system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 125
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 6
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Terminology_TX_NoValid_1_CC"
              }
            ],
            "severity": "error",
            "code": "code-invalid",
            "details": {
              "text": "None of the codings provided are in the value set 'Specialty' (https://fhir.nwgenomics.nhs.uk/ValueSet/specialty|0.1.0), and a coding from this value set is required) (codes = http://snomed.info/sct#907271000000106)"
            },
            "expression": [
              "DocumentReference/Y05868-d783361d-83fa-438f-977c-601f30ef5ceb: DocumentReference.context.practiceSetting"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 156
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 58
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://fhir.nhs.uk/Id/nhsSpineASID'"
            },
            "expression": [
              "DocumentReference/Y05868-d783361d-83fa-438f-977c-601f30ef5ceb: DocumentReference.context.related[0].identifier.system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 160
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Reference_REF_CantResolve"
              }
            ],
            "severity": "error",
            "code": "structure",
            "details": {
              "text": "Unable to resolve resource with reference 'https://gen-tie-test.nwgenomics.nhs.uk/cdr/fhir/r4/ServiceRequest/1787'"
            },
            "expression": [
              "DocumentReference/Y05868-d783361d-83fa-438f-977c-601f30ef5ceb: DocumentReference.context.related[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 181
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Reference_REF_CantResolve"
              }
            ],
            "severity": "error",
            "code": "structure",
            "details": {
              "text": "Unable to resolve resource with reference 'https://gen-tie-test.nwgenomics.nhs.uk/cdr/fhir/r4/DiagnosticReport/1788'"
            },
            "expression": [
              "DocumentReference/Y05868-d783361d-83fa-438f-977c-601f30ef5ceb: DocumentReference.context.related[2]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 193
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 72
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://fhir.nwgenomics.nhs.uk/iGene/ReportNumber'"
            },
            "expression": [
              "DocumentReference/Y05868-d783361d-83fa-438f-977c-601f30ef5ceb: DocumentReference.context.related[2].identifier.system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/DocumentReference-Y05868-75c254c0-d2cf-43ee-8a83-926af3f302bb",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "DocumentReference-Y05868-75c254c0-d2cf-43ee-8a83-926af3f302bb",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 20
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 68
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://fhir.nwgenomics.nhs.uk/iGene/ReportNumber'"
            },
            "expression": [
              "DocumentReference/Y05868-75c254c0-d2cf-43ee-8a83-926af3f302bb: DocumentReference.identifier[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 31
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 4
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Terminology_TX_NoValid_1_CC"
              }
            ],
            "severity": "error",
            "code": "code-invalid",
            "details": {
              "text": "None of the codings provided are in the value set 'DocumentEntry Type' (https://fhir.nwgenomics.nhs.uk/ValueSet/document-entry-type|0.1.0), and a coding from this value set is required) (codes = http://snomed.info/sct#887701000000100)"
            },
            "expression": [
              "DocumentReference/Y05868-75c254c0-d2cf-43ee-8a83-926af3f302bb: DocumentReference.type"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 89
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Extension_EXT_Unknown_NotHere"
              }
            ],
            "severity": "error",
            "code": "structure",
            "details": {
              "text": "The extension https://fhir.nhs.uk/England/StructureDefinition/Extension-England-ContentStability could not be found so is not allowed here"
            },
            "expression": [
              "DocumentReference/Y05868-75c254c0-d2cf-43ee-8a83-926af3f302bb: DocumentReference.content[0].extension[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 99
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 102
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://fhir.nhs.uk/England/StructureDefinition/Extension-England-ContentStability'"
            },
            "expression": [
              "DocumentReference/Y05868-75c254c0-d2cf-43ee-8a83-926af3f302bb: DocumentReference.content[0].extension[0].url"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 90
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 12
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "UNKNOWN_CODESYSTEM"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'https://fhir.nhs.uk/England/CodeSystem/England-NRLContentStability' could not be found, so the code cannot be validated"
            },
            "expression": [
              "DocumentReference/Y05868-75c254c0-d2cf-43ee-8a83-926af3f302bb: DocumentReference.content[0].extension[0].value.ofType(CodeableConcept).coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 101
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Extension_EXT_Unknown_NotHere"
              }
            ],
            "severity": "error",
            "code": "structure",
            "details": {
              "text": "The extension https://fhir.nhs.uk/England/StructureDefinition/Extension-England-NRLRetrievalMechanism could not be found so is not allowed here"
            },
            "expression": [
              "DocumentReference/Y05868-75c254c0-d2cf-43ee-8a83-926af3f302bb: DocumentReference.content[0].extension[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 111
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 107
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://fhir.nhs.uk/England/StructureDefinition/Extension-England-NRLRetrievalMechanism'"
            },
            "expression": [
              "DocumentReference/Y05868-75c254c0-d2cf-43ee-8a83-926af3f302bb: DocumentReference.content[0].extension[1].url"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 102
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 12
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "UNKNOWN_CODESYSTEM"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'https://fhir.nhs.uk/England/CodeSystem/England-NRLRetrievalMechanism' could not be found, so the code cannot be validated"
            },
            "expression": [
              "DocumentReference/Y05868-75c254c0-d2cf-43ee-8a83-926af3f302bb: DocumentReference.content[0].extension[1].value.ofType(CodeableConcept).coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 119
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "UNKNOWN_CODESYSTEM"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'https://fhir.nhs.uk/England/CodeSystem/England-NRLFormatCode' could not be found, so the code cannot be validated"
            },
            "expression": [
              "DocumentReference/Y05868-75c254c0-d2cf-43ee-8a83-926af3f302bb: DocumentReference.content[0].format.system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 128
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Reference_REF_CantResolve"
              }
            ],
            "severity": "error",
            "code": "structure",
            "details": {
              "text": "Unable to resolve resource with reference 'https://gen-tie-test.nwgenomics.nhs.uk/cdr/fhir/r4/Encounter/1661'"
            },
            "expression": [
              "DocumentReference/Y05868-75c254c0-d2cf-43ee-8a83-926af3f302bb: DocumentReference.context.encounter[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 132
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 12
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TYPE_CHECKS_PATTERN_CC"
              }
            ],
            "severity": "error",
            "code": "value",
            "details": {
              "text": "The pattern [system http://terminology.hl7.org/CodeSystem/v2-0203, code AN, and display 'Account number'] defined in the profile https://fhir.nwgenomics.nhs.uk/StructureDefinition/HospitalProviderSpellIdentifier|0.1.0 not found. Issues: [ValidationMessage[level=ERROR,type=VALUE,location=DocumentReference.context.encounter[0].identifier.type.coding.code,message=Value is 'VN' but is fixed to 'AN' in the profile https://fhir.nwgenomics.nhs.uk/StructureDefinition/HospitalProviderSpellIdentifier|0.1.0#Identifier], ValidationMessage[level=ERROR,type=VALUE,location=DocumentReference.context.encounter[0].identifier.type.coding.display,message=Missing element 'display' - required by fixed value assigned in profile https://fhir.nwgenomics.nhs.uk/StructureDefinition/HospitalProviderSpellIdentifier|0.1.0]]"
            },
            "expression": [
              "DocumentReference/Y05868-75c254c0-d2cf-43ee-8a83-926af3f302bb: DocumentReference.context.encounter[0].identifier.type"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 154
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 6
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Terminology_TX_NoValid_1_CC"
              }
            ],
            "severity": "error",
            "code": "code-invalid",
            "details": {
              "text": "None of the codings provided are in the value set 'Specialty' (https://fhir.nwgenomics.nhs.uk/ValueSet/specialty|0.1.0), and a coding from this value set is required) (codes = http://snomed.info/sct#907271000000106)"
            },
            "expression": [
              "DocumentReference/Y05868-75c254c0-d2cf-43ee-8a83-926af3f302bb: DocumentReference.context.practiceSetting"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 173
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 68
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'urn:oid:1.2.840.114350.1.13.611.3.7.5.737384.14'"
            },
            "expression": [
              "DocumentReference/Y05868-75c254c0-d2cf-43ee-8a83-926af3f302bb: DocumentReference.context.sourcePatientInfo.identifier.system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 186
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 58
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://fhir.nhs.uk/Id/nhsSpineASID'"
            },
            "expression": [
              "DocumentReference/Y05868-75c254c0-d2cf-43ee-8a83-926af3f302bb: DocumentReference.context.related[0].identifier.system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 190
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Reference_REF_CantResolve"
              }
            ],
            "severity": "error",
            "code": "structure",
            "details": {
              "text": "Unable to resolve resource with reference 'https://gen-tie-test.nwgenomics.nhs.uk/cdr/fhir/r4/ServiceRequest/1663'"
            },
            "expression": [
              "DocumentReference/Y05868-75c254c0-d2cf-43ee-8a83-926af3f302bb: DocumentReference.context.related[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 202
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 67
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'urn:oid:1.2.840.114350.1.13.861.1.7.2.798268'"
            },
            "expression": [
              "DocumentReference/Y05868-75c254c0-d2cf-43ee-8a83-926af3f302bb: DocumentReference.context.related[1].identifier.system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 212
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Reference_REF_CantResolve"
              }
            ],
            "severity": "error",
            "code": "structure",
            "details": {
              "text": "Unable to resolve resource with reference 'https://gen-tie-test.nwgenomics.nhs.uk/cdr/fhir/r4/DiagnosticReport/1676'"
            },
            "expression": [
              "DocumentReference/Y05868-75c254c0-d2cf-43ee-8a83-926af3f302bb: DocumentReference.context.related[2]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 224
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 72
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://fhir.nwgenomics.nhs.uk/iGene/ReportNumber'"
            },
            "expression": [
              "DocumentReference/Y05868-75c254c0-d2cf-43ee-8a83-926af3f302bb: DocumentReference.context.related[2].identifier.system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/Questionnaire-81247-9",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Questionnaire-81247-9"
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/Observation-brca1-variant",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Observation-brca1-variant",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 79
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 14
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "Unable to check whether the code is in the value set '' because the code system http://www.genenames.org was not found"
            },
            "expression": [
              "Observation/brca1-variant: Observation.component[0].value.ofType(CodeableConcept)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 79
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 14
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"
            },
            "expression": [
              "Observation/brca1-variant: Observation.component[0].value.ofType(CodeableConcept).coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 119
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 14
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              }
            ],
            "severity": "error",
            "code": "code-invalid",
            "details": {
              "text": "Error from https://tx.fhir.org/r4: Error parsing HGVS response: HTTP/1.1 400 Bad request"
            },
            "expression": [
              "Observation/brca1-variant: Observation.component[2].value.ofType(CodeableConcept).coding[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 119
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 14
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Terminology_TX_NoValid_1_CC"
              }
            ],
            "severity": "error",
            "code": "code-invalid",
            "details": {
              "text": "None of the codings provided are in the value set 'Human Genome Variation Society (HGVS) Nomenclature' (http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs|3.0.0), and a coding from this value set is required) (codes = http://varnomen.hgvs.org#BRCA1:c.3143delG p.(Gly1048ValfsTer14))"
            },
            "expression": [
              "Observation/brca1-variant: Observation.component[2].value.ofType(CodeableConcept)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 2
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "All_observations_should_have_a_performer"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Best Practice Recommendation: In general, all observations should have a performer"
            },
            "expression": [
              "Observation/brca1-variant: Observation"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 2
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "All_observations_should_have_an_effectiveDateTime_or_an_effectivePeriod"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Best Practice Recommendation: In general, all observations should have an effective[x] ()"
            },
            "expression": [
              "Observation/brca1-variant: Observation"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/Observation-m2-diagnostic-implication",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Observation-m2-diagnostic-implication",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 87
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 14
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "UNKNOWN_CODE_IN_FRAGMENT"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "Unknown Code 'M2' in the CodeSystem 'https://fhir.nhs.uk/CodeSystem/England-GenomicTestDirectory' version '0.1.0' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"
            },
            "expression": [
              "Observation/m2-diagnostic-implication: Observation.component[1].value.ofType(CodeableConcept).coding[1].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 2
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "All_observations_should_have_a_performer"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Best Practice Recommendation: In general, all observations should have a performer"
            },
            "expression": [
              "Observation/m2-diagnostic-implication: Observation"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 2
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "All_observations_should_have_an_effectiveDateTime_or_an_effectivePeriod"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Best Practice Recommendation: In general, all observations should have an effective[x] ()"
            },
            "expression": [
              "Observation/m2-diagnostic-implication: Observation"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/OperationOutcome-operation-outcome-validate",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "OperationOutcome-operation-outcome-validate",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 18
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Extension_EXT_Type"
              }
            ],
            "severity": "error",
            "code": "structure",
            "details": {
              "text": "The Extension 'http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col' definition allows for the types [string] but found type integer"
            },
            "expression": [
              "OperationOutcome/operation-outcome-validate: OperationOutcome.issue[0].extension[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 26
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Extension_EXT_Type"
              }
            ],
            "severity": "error",
            "code": "structure",
            "details": {
              "text": "The Extension 'http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id' definition allows for the types [string] but found type code"
            },
            "expression": [
              "OperationOutcome/operation-outcome-validate: OperationOutcome.issue[0].extension[3]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 42
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Extension_EXT_Type"
              }
            ],
            "severity": "error",
            "code": "structure",
            "details": {
              "text": "The Extension 'http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col' definition allows for the types [string] but found type integer"
            },
            "expression": [
              "OperationOutcome/operation-outcome-validate: OperationOutcome.issue[1].extension[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 50
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Extension_EXT_Type"
              }
            ],
            "severity": "error",
            "code": "structure",
            "details": {
              "text": "The Extension 'http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id' definition allows for the types [string] but found type code"
            },
            "expression": [
              "OperationOutcome/operation-outcome-validate: OperationOutcome.issue[1].extension[3]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 66
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Extension_EXT_Type"
              }
            ],
            "severity": "error",
            "code": "structure",
            "details": {
              "text": "The Extension 'http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col' definition allows for the types [string] but found type integer"
            },
            "expression": [
              "OperationOutcome/operation-outcome-validate: OperationOutcome.issue[2].extension[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 74
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Extension_EXT_Type"
              }
            ],
            "severity": "error",
            "code": "structure",
            "details": {
              "text": "The Extension 'http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id' definition allows for the types [string] but found type code"
            },
            "expression": [
              "OperationOutcome/operation-outcome-validate: OperationOutcome.issue[2].extension[3]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 90
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Extension_EXT_Type"
              }
            ],
            "severity": "error",
            "code": "structure",
            "details": {
              "text": "The Extension 'http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col' definition allows for the types [string] but found type integer"
            },
            "expression": [
              "OperationOutcome/operation-outcome-validate: OperationOutcome.issue[3].extension[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 98
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Extension_EXT_Type"
              }
            ],
            "severity": "error",
            "code": "structure",
            "details": {
              "text": "The Extension 'http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id' definition allows for the types [string] but found type code"
            },
            "expression": [
              "OperationOutcome/operation-outcome-validate: OperationOutcome.issue[3].extension[3]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 114
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Extension_EXT_Type"
              }
            ],
            "severity": "error",
            "code": "structure",
            "details": {
              "text": "The Extension 'http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col' definition allows for the types [string] but found type integer"
            },
            "expression": [
              "OperationOutcome/operation-outcome-validate: OperationOutcome.issue[4].extension[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 122
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Extension_EXT_Type"
              }
            ],
            "severity": "error",
            "code": "structure",
            "details": {
              "text": "The Extension 'http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id' definition allows for the types [string] but found type code"
            },
            "expression": [
              "OperationOutcome/operation-outcome-validate: OperationOutcome.issue[4].extension[3]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 138
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Extension_EXT_Type"
              }
            ],
            "severity": "error",
            "code": "structure",
            "details": {
              "text": "The Extension 'http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col' definition allows for the types [string] but found type integer"
            },
            "expression": [
              "OperationOutcome/operation-outcome-validate: OperationOutcome.issue[5].extension[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 146
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Extension_EXT_Type"
              }
            ],
            "severity": "error",
            "code": "structure",
            "details": {
              "text": "The Extension 'http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id' definition allows for the types [string] but found type code"
            },
            "expression": [
              "OperationOutcome/operation-outcome-validate: OperationOutcome.issue[5].extension[3]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 162
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Extension_EXT_Type"
              }
            ],
            "severity": "error",
            "code": "structure",
            "details": {
              "text": "The Extension 'http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col' definition allows for the types [string] but found type integer"
            },
            "expression": [
              "OperationOutcome/operation-outcome-validate: OperationOutcome.issue[6].extension[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 170
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Extension_EXT_Type"
              }
            ],
            "severity": "error",
            "code": "structure",
            "details": {
              "text": "The Extension 'http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id' definition allows for the types [string] but found type code"
            },
            "expression": [
              "OperationOutcome/operation-outcome-validate: OperationOutcome.issue[6].extension[3]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 186
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Extension_EXT_Type"
              }
            ],
            "severity": "error",
            "code": "structure",
            "details": {
              "text": "The Extension 'http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col' definition allows for the types [string] but found type integer"
            },
            "expression": [
              "OperationOutcome/operation-outcome-validate: OperationOutcome.issue[7].extension[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 194
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Extension_EXT_Type"
              }
            ],
            "severity": "error",
            "code": "structure",
            "details": {
              "text": "The Extension 'http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id' definition allows for the types [string] but found type code"
            },
            "expression": [
              "OperationOutcome/operation-outcome-validate: OperationOutcome.issue[7].extension[3]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 210
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Extension_EXT_Type"
              }
            ],
            "severity": "error",
            "code": "structure",
            "details": {
              "text": "The Extension 'http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col' definition allows for the types [string] but found type integer"
            },
            "expression": [
              "OperationOutcome/operation-outcome-validate: OperationOutcome.issue[8].extension[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 218
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Extension_EXT_Type"
              }
            ],
            "severity": "error",
            "code": "structure",
            "details": {
              "text": "The Extension 'http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id' definition allows for the types [string] but found type code"
            },
            "expression": [
              "OperationOutcome/operation-outcome-validate: OperationOutcome.issue[8].extension[3]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 234
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Extension_EXT_Type"
              }
            ],
            "severity": "error",
            "code": "structure",
            "details": {
              "text": "The Extension 'http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col' definition allows for the types [string] but found type integer"
            },
            "expression": [
              "OperationOutcome/operation-outcome-validate: OperationOutcome.issue[9].extension[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 242
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Extension_EXT_Type"
              }
            ],
            "severity": "error",
            "code": "structure",
            "details": {
              "text": "The Extension 'http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id' definition allows for the types [string] but found type code"
            },
            "expression": [
              "OperationOutcome/operation-outcome-validate: OperationOutcome.issue[9].extension[3]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 258
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Extension_EXT_Type"
              }
            ],
            "severity": "error",
            "code": "structure",
            "details": {
              "text": "The Extension 'http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col' definition allows for the types [string] but found type integer"
            },
            "expression": [
              "OperationOutcome/operation-outcome-validate: OperationOutcome.issue[10].extension[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 266
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Extension_EXT_Type"
              }
            ],
            "severity": "error",
            "code": "structure",
            "details": {
              "text": "The Extension 'http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id' definition allows for the types [string] but found type code"
            },
            "expression": [
              "OperationOutcome/operation-outcome-validate: OperationOutcome.issue[10].extension[3]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 282
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Extension_EXT_Type"
              }
            ],
            "severity": "error",
            "code": "structure",
            "details": {
              "text": "The Extension 'http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col' definition allows for the types [string] but found type integer"
            },
            "expression": [
              "OperationOutcome/operation-outcome-validate: OperationOutcome.issue[11].extension[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 290
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Extension_EXT_Type"
              }
            ],
            "severity": "error",
            "code": "structure",
            "details": {
              "text": "The Extension 'http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id' definition allows for the types [string] but found type code"
            },
            "expression": [
              "OperationOutcome/operation-outcome-validate: OperationOutcome.issue[11].extension[3]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 306
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Extension_EXT_Type"
              }
            ],
            "severity": "error",
            "code": "structure",
            "details": {
              "text": "The Extension 'http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col' definition allows for the types [string] but found type integer"
            },
            "expression": [
              "OperationOutcome/operation-outcome-validate: OperationOutcome.issue[12].extension[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 314
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Extension_EXT_Type"
              }
            ],
            "severity": "error",
            "code": "structure",
            "details": {
              "text": "The Extension 'http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id' definition allows for the types [string] but found type code"
            },
            "expression": [
              "OperationOutcome/operation-outcome-validate: OperationOutcome.issue[12].extension[3]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 330
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Extension_EXT_Type"
              }
            ],
            "severity": "error",
            "code": "structure",
            "details": {
              "text": "The Extension 'http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col' definition allows for the types [string] but found type integer"
            },
            "expression": [
              "OperationOutcome/operation-outcome-validate: OperationOutcome.issue[13].extension[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 338
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Extension_EXT_Type"
              }
            ],
            "severity": "error",
            "code": "structure",
            "details": {
              "text": "The Extension 'http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id' definition allows for the types [string] but found type code"
            },
            "expression": [
              "OperationOutcome/operation-outcome-validate: OperationOutcome.issue[13].extension[3]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 354
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Extension_EXT_Type"
              }
            ],
            "severity": "error",
            "code": "structure",
            "details": {
              "text": "The Extension 'http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col' definition allows for the types [string] but found type integer"
            },
            "expression": [
              "OperationOutcome/operation-outcome-validate: OperationOutcome.issue[14].extension[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 362
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Extension_EXT_Type"
              }
            ],
            "severity": "error",
            "code": "structure",
            "details": {
              "text": "The Extension 'http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id' definition allows for the types [string] but found type code"
            },
            "expression": [
              "OperationOutcome/operation-outcome-validate: OperationOutcome.issue[14].extension[3]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 378
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Extension_EXT_Type"
              }
            ],
            "severity": "error",
            "code": "structure",
            "details": {
              "text": "The Extension 'http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col' definition allows for the types [string] but found type integer"
            },
            "expression": [
              "OperationOutcome/operation-outcome-validate: OperationOutcome.issue[15].extension[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 386
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Extension_EXT_Type"
              }
            ],
            "severity": "error",
            "code": "structure",
            "details": {
              "text": "The Extension 'http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id' definition allows for the types [string] but found type code"
            },
            "expression": [
              "OperationOutcome/operation-outcome-validate: OperationOutcome.issue[15].extension[3]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 402
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Extension_EXT_Type"
              }
            ],
            "severity": "error",
            "code": "structure",
            "details": {
              "text": "The Extension 'http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col' definition allows for the types [string] but found type integer"
            },
            "expression": [
              "OperationOutcome/operation-outcome-validate: OperationOutcome.issue[16].extension[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 410
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Extension_EXT_Type"
              }
            ],
            "severity": "error",
            "code": "structure",
            "details": {
              "text": "The Extension 'http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id' definition allows for the types [string] but found type code"
            },
            "expression": [
              "OperationOutcome/operation-outcome-validate: OperationOutcome.issue[16].extension[3]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 426
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Extension_EXT_Type"
              }
            ],
            "severity": "error",
            "code": "structure",
            "details": {
              "text": "The Extension 'http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col' definition allows for the types [string] but found type integer"
            },
            "expression": [
              "OperationOutcome/operation-outcome-validate: OperationOutcome.issue[17].extension[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 434
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Extension_EXT_Type"
              }
            ],
            "severity": "error",
            "code": "structure",
            "details": {
              "text": "The Extension 'http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id' definition allows for the types [string] but found type code"
            },
            "expression": [
              "OperationOutcome/operation-outcome-validate: OperationOutcome.issue[17].extension[3]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 450
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Extension_EXT_Type"
              }
            ],
            "severity": "error",
            "code": "structure",
            "details": {
              "text": "The Extension 'http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col' definition allows for the types [string] but found type integer"
            },
            "expression": [
              "OperationOutcome/operation-outcome-validate: OperationOutcome.issue[18].extension[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 458
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Extension_EXT_Type"
              }
            ],
            "severity": "error",
            "code": "structure",
            "details": {
              "text": "The Extension 'http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id' definition allows for the types [string] but found type code"
            },
            "expression": [
              "OperationOutcome/operation-outcome-validate: OperationOutcome.issue[18].extension[3]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 474
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Extension_EXT_Type"
              }
            ],
            "severity": "error",
            "code": "structure",
            "details": {
              "text": "The Extension 'http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col' definition allows for the types [string] but found type integer"
            },
            "expression": [
              "OperationOutcome/operation-outcome-validate: OperationOutcome.issue[19].extension[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 482
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Extension_EXT_Type"
              }
            ],
            "severity": "error",
            "code": "structure",
            "details": {
              "text": "The Extension 'http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id' definition allows for the types [string] but found type code"
            },
            "expression": [
              "OperationOutcome/operation-outcome-validate: OperationOutcome.issue[19].extension[3]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 498
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Extension_EXT_Type"
              }
            ],
            "severity": "error",
            "code": "structure",
            "details": {
              "text": "The Extension 'http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col' definition allows for the types [string] but found type integer"
            },
            "expression": [
              "OperationOutcome/operation-outcome-validate: OperationOutcome.issue[20].extension[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 506
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Extension_EXT_Type"
              }
            ],
            "severity": "error",
            "code": "structure",
            "details": {
              "text": "The Extension 'http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id' definition allows for the types [string] but found type code"
            },
            "expression": [
              "OperationOutcome/operation-outcome-validate: OperationOutcome.issue[20].extension[3]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 522
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Extension_EXT_Type"
              }
            ],
            "severity": "error",
            "code": "structure",
            "details": {
              "text": "The Extension 'http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col' definition allows for the types [string] but found type integer"
            },
            "expression": [
              "OperationOutcome/operation-outcome-validate: OperationOutcome.issue[21].extension[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 530
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Extension_EXT_Type"
              }
            ],
            "severity": "error",
            "code": "structure",
            "details": {
              "text": "The Extension 'http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id' definition allows for the types [string] but found type code"
            },
            "expression": [
              "OperationOutcome/operation-outcome-validate: OperationOutcome.issue[21].extension[3]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 546
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Extension_EXT_Type"
              }
            ],
            "severity": "error",
            "code": "structure",
            "details": {
              "text": "The Extension 'http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col' definition allows for the types [string] but found type integer"
            },
            "expression": [
              "OperationOutcome/operation-outcome-validate: OperationOutcome.issue[22].extension[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 554
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Extension_EXT_Type"
              }
            ],
            "severity": "error",
            "code": "structure",
            "details": {
              "text": "The Extension 'http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id' definition allows for the types [string] but found type code"
            },
            "expression": [
              "OperationOutcome/operation-outcome-validate: OperationOutcome.issue[22].extension[3]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 570
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Extension_EXT_Type"
              }
            ],
            "severity": "error",
            "code": "structure",
            "details": {
              "text": "The Extension 'http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col' definition allows for the types [string] but found type integer"
            },
            "expression": [
              "OperationOutcome/operation-outcome-validate: OperationOutcome.issue[23].extension[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 590
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Extension_EXT_Type"
              }
            ],
            "severity": "error",
            "code": "structure",
            "details": {
              "text": "The Extension 'http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col' definition allows for the types [string] but found type integer"
            },
            "expression": [
              "OperationOutcome/operation-outcome-validate: OperationOutcome.issue[24].extension[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 610
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Extension_EXT_Type"
              }
            ],
            "severity": "error",
            "code": "structure",
            "details": {
              "text": "The Extension 'http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col' definition allows for the types [string] but found type integer"
            },
            "expression": [
              "OperationOutcome/operation-outcome-validate: OperationOutcome.issue[25].extension[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 630
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Extension_EXT_Type"
              }
            ],
            "severity": "error",
            "code": "structure",
            "details": {
              "text": "The Extension 'http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col' definition allows for the types [string] but found type integer"
            },
            "expression": [
              "OperationOutcome/operation-outcome-validate: OperationOutcome.issue[26].extension[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 650
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Extension_EXT_Type"
              }
            ],
            "severity": "error",
            "code": "structure",
            "details": {
              "text": "The Extension 'http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col' definition allows for the types [string] but found type integer"
            },
            "expression": [
              "OperationOutcome/operation-outcome-validate: OperationOutcome.issue[27].extension[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 670
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Extension_EXT_Type"
              }
            ],
            "severity": "error",
            "code": "structure",
            "details": {
              "text": "The Extension 'http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col' definition allows for the types [string] but found type integer"
            },
            "expression": [
              "OperationOutcome/operation-outcome-validate: OperationOutcome.issue[28].extension[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 690
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Extension_EXT_Type"
              }
            ],
            "severity": "error",
            "code": "structure",
            "details": {
              "text": "The Extension 'http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col' definition allows for the types [string] but found type integer"
            },
            "expression": [
              "OperationOutcome/operation-outcome-validate: OperationOutcome.issue[29].extension[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 710
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Extension_EXT_Type"
              }
            ],
            "severity": "error",
            "code": "structure",
            "details": {
              "text": "The Extension 'http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col' definition allows for the types [string] but found type integer"
            },
            "expression": [
              "OperationOutcome/operation-outcome-validate: OperationOutcome.issue[30].extension[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 730
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Extension_EXT_Type"
              }
            ],
            "severity": "error",
            "code": "structure",
            "details": {
              "text": "The Extension 'http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col' definition allows for the types [string] but found type integer"
            },
            "expression": [
              "OperationOutcome/operation-outcome-validate: OperationOutcome.issue[31].extension[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 750
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Extension_EXT_Type"
              }
            ],
            "severity": "error",
            "code": "structure",
            "details": {
              "text": "The Extension 'http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col' definition allows for the types [string] but found type integer"
            },
            "expression": [
              "OperationOutcome/operation-outcome-validate: OperationOutcome.issue[32].extension[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 770
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Extension_EXT_Type"
              }
            ],
            "severity": "error",
            "code": "structure",
            "details": {
              "text": "The Extension 'http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col' definition allows for the types [string] but found type integer"
            },
            "expression": [
              "OperationOutcome/operation-outcome-validate: OperationOutcome.issue[33].extension[1]"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/Questionnaire-Pedigree",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Questionnaire-Pedigree",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 16496
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Validation_VAL_Profile_MatchMultiple"
              }
            ],
            "severity": "error",
            "code": "invalid",
            "details": {
              "text": "Profile https://fhir.nwgenomics.nhs.uk/StructureDefinition/NWQuestionnaire|0.1.0, Element matches more than one slice - terminologyServer, preferredTerminologyServer"
            },
            "expression": [
              "Questionnaire/Pedigree: Questionnaire.item[1].extension[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 16495
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://snowstorm.ihtsdotools.org/fhir'"
            },
            "expression": [
              "Questionnaire/Pedigree: Questionnaire.item[1].extension[0].value.ofType(url)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 16735
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TYPE_SPECIFIC_CHECKS_DT_CANONICAL_RESOLVE"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "A definition could not be found for Canonical URL 'http://snomed.info/sct/900000000000207008?fhir_vs=ecl/%3C734840008'"
            },
            "expression": [
              "Questionnaire/Pedigree: Questionnaire.item[1].answerValueSet"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 16904
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Validation_VAL_Profile_MatchMultiple"
              }
            ],
            "severity": "error",
            "code": "invalid",
            "details": {
              "text": "Profile https://fhir.nwgenomics.nhs.uk/StructureDefinition/NWQuestionnaire|0.1.0, Element matches more than one slice - terminologyServer, preferredTerminologyServer"
            },
            "expression": [
              "Questionnaire/Pedigree: Questionnaire.item[2].extension[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 16903
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://snowstorm.ihtsdotools.org/fhir'"
            },
            "expression": [
              "Questionnaire/Pedigree: Questionnaire.item[2].extension[0].value.ofType(url)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 17167
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TYPE_SPECIFIC_CHECKS_DT_CANONICAL_RESOLVE"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "A definition could not be found for Canonical URL 'http://snomed.info/sct/900000000000207008?fhir_vs=ecl/%3C95462004'"
            },
            "expression": [
              "Questionnaire/Pedigree: Questionnaire.item[2].answerValueSet"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 17491
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://snowstorm.ihtsdotools.org/fhir'"
            },
            "expression": [
              "Questionnaire/Pedigree: Questionnaire.item[3].item[1].extension[0].value.ofType(url)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 17740
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TYPE_SPECIFIC_CHECKS_DT_CANONICAL_RESOLVE"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "A definition could not be found for Canonical URL 'http://snomed.info/sct/900000000000207008?fhir_vs=ecl/%3C303071001'"
            },
            "expression": [
              "Questionnaire/Pedigree: Questionnaire.item[3].item[1].answerValueSet"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/NamingSystem-gmcnumber-namingsystem",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "NamingSystem-gmcnumber-namingsystem",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 2494
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/NamingSystem#nsd-0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: nsd-0: 'Name should be usable as an identifier for the module by machine processing applications such as code generation (name.matches('[A-Z]([A-Za-z0-9_]){0,254}'))'"
            },
            "expression": [
              "NamingSystem/gmcnumber-namingsystem: NamingSystem"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/NamingSystem-gmpnumber-namingsystem",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "NamingSystem-gmpnumber-namingsystem",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 2062
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/NamingSystem#nsd-0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: nsd-0: 'Name should be usable as an identifier for the module by machine processing applications such as code generation (name.matches('[A-Z]([A-Za-z0-9_]){0,254}'))'"
            },
            "expression": [
              "NamingSystem/gmpnumber-namingsystem: NamingSystem"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/NamingSystem-nhs-number-namingsystem",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "NamingSystem-nhs-number-namingsystem",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 2484
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/NamingSystem#nsd-0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: nsd-0: 'Name should be usable as an identifier for the module by machine processing applications such as code generation (name.matches('[A-Z]([A-Za-z0-9_]){0,254}'))'"
            },
            "expression": [
              "NamingSystem/nhs-number-namingsystem: NamingSystem"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/NamingSystem-ods-organization-code-namingsystem",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "NamingSystem-ods-organization-code-namingsystem",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 2504
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/NamingSystem#nsd-0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: nsd-0: 'Name should be usable as an identifier for the module by machine processing applications such as code generation (name.matches('[A-Z]([A-Za-z0-9_]){0,254}'))'"
            },
            "expression": [
              "NamingSystem/ods-organization-code-namingsystem: NamingSystem"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://fhir.nwgenomics.nhs.uk/OperationOutcome/NamingSystem-ods-site-code-namingsystem",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "NamingSystem-ods-site-code-namingsystem",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 2046
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/NamingSystem#nsd-0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: nsd-0: 'Name should be usable as an identifier for the module by machine processing applications such as code generation (name.matches('[A-Z]([A-Za-z0-9_]){0,254}'))'"
            },
            "expression": [
              "NamingSystem/ods-site-code-namingsystem: NamingSystem"
            ]
          }
        ]
      }
    }
  ]
}