FHIRsmith: CodeSystem/CodeSystem-ocm-protocol-markers-cs.json

FHIR IG analytics

Package	fhir.ke.nccp
Resource Type	CodeSystem
Id	CodeSystem-ocm-protocol-markers-cs.json
FHIR Version	R4
Source	https://build.fhir.org/ig/IntelliSOFT-Consulting/nccpFHIRIG/CodeSystem-ocm-protocol-markers-cs.html
URL	https://nshr-uat.sha.go.ke/fhir/CodeSystem/ocm-protocol-markers-cs
Version	0.1.0
Status	active
Date	2026-06-08T10:30:33+00:00
Name	OCMProtocolMarkersCS
Title	Kenya OCM Protocol Markers Code System
Realm	us
Authority	hl7
Description	Biomarker and molecular marker codes used for treatment protocol selection.
Content	complete

Resources that use this resource

ValueSet
fhir.ke.nccp#current	nccp-ocm-protocol-markers-vs	Kenya OCM Protocol Markers Value Set

Resources that this resource uses

No resources found

Narrative

Note: links and images are rebased to the (stated) source

Generated Narrative: CodeSystem ocm-protocol-markers-cs

This case-sensitive code system https://nshr-uat.sha.go.ke/fhir/CodeSystem/ocm-protocol-markers-cs defines the following codes:

Code	Display	Definition
HER2-POSITIVE	HER2 Positive	HER2/neu overexpression or amplification detected.
HER2-NEGATIVE	HER2 Negative	No HER2/neu overexpression or amplification.
ER-POSITIVE	ER Positive	Oestrogen receptor positive.
ER-NEGATIVE	ER Negative	Oestrogen receptor negative.
PR-POSITIVE	PR Positive	Progesterone receptor positive.
PR-NEGATIVE	PR Negative	Progesterone receptor negative.
TRIPLE-NEGATIVE	Triple Negative	ER-, PR-, HER2- breast cancer.
KRAS-MUTANT	KRAS Mutant	KRAS mutation detected.
KRAS-WILD-TYPE	KRAS Wild-type	No KRAS mutation.
BRAF-V600E	BRAF V600E Mutant	BRAF V600E mutation detected.
PD-L1-POSITIVE	PD-L1 Positive	PD-L1 expression ≥1%.
PD-L1-NEGATIVE	PD-L1 Negative	PD-L1 expression <1%.
MSI-HIGH	MSI-High	Microsatellite instability high.
MSI-LOW	MSI-Low / MSS	Microsatellite instability low or stable.
EGFR-MUTANT	EGFR Mutant	EGFR mutation detected.
ALK-POSITIVE	ALK Positive	ALK rearrangement detected.
NOT-TESTED	Not Tested	Biomarker testing not performed.

Source1

{
  "resourceType": "CodeSystem",
  "id": "ocm-protocol-markers-cs",
  "text": {
    "status": "generated",
    "div": "<!-- snip (see above) -->"
  },
  "url": "https://nshr-uat.sha.go.ke/fhir/CodeSystem/ocm-protocol-markers-cs",
  "version": "0.1.0",
  "name": "OCMProtocolMarkersCS",
  "title": "Kenya OCM Protocol Markers Code System",
  "status": "active",
  "experimental": false,
  "date": "2026-06-08T10:30:33+00:00",
  "publisher": "Digital Health Agency (DHA), Kenya",
  "contact": [
    {
      "name": "Digital Health Agency (DHA), Kenya",
      "telecom": [
        {
          "system": "url",
          "value": "https://dha.go.ke"
        },
        {
          "system": "email",
          "value": "info@dha.go.ke"
        }
      ]
    },
    {
      "name": "Digital Health Agency Kenya – FHIR Team",
      "telecom": [
        {
          "system": "email",
          "value": "info@dha.go.ke",
          "use": "work"
        },
        {
          "system": "url",
          "value": "https://dha.go.ke",
          "use": "work"
        }
      ]
    }
  ],
  "description": "Biomarker and molecular marker codes used for treatment protocol selection.",
  "jurisdiction": [
    {
      "coding": [
        {
          "system": "urn:iso:std:iso:3166",
          "code": "KE",
          "display": "Kenya"
        }
      ]
    }
  ],
  "caseSensitive": true,
  "content": "complete",
  "count": 17,
  "concept": [
    {
      "code": "HER2-POSITIVE",
      "display": "HER2 Positive",
      "definition": "HER2/neu overexpression or amplification detected."
    },
    {
      "code": "HER2-NEGATIVE",
      "display": "HER2 Negative",
      "definition": "No HER2/neu overexpression or amplification."
    },
    {
      "code": "ER-POSITIVE",
      "display": "ER Positive",
      "definition": "Oestrogen receptor positive."
    },
    {
      "code": "ER-NEGATIVE",
      "display": "ER Negative",
      "definition": "Oestrogen receptor negative."
    },
    {
      "code": "PR-POSITIVE",
      "display": "PR Positive",
      "definition": "Progesterone receptor positive."
    },
    {
      "code": "PR-NEGATIVE",
      "display": "PR Negative",
      "definition": "Progesterone receptor negative."
    },
    {
      "code": "TRIPLE-NEGATIVE",
      "display": "Triple Negative",
      "definition": "ER-, PR-, HER2- breast cancer."
    },
    {
      "code": "KRAS-MUTANT",
      "display": "KRAS Mutant",
      "definition": "KRAS mutation detected."
    },
    {
      "code": "KRAS-WILD-TYPE",
      "display": "KRAS Wild-type",
      "definition": "No KRAS mutation."
    },
    {
      "code": "BRAF-V600E",
      "display": "BRAF V600E Mutant",
      "definition": "BRAF V600E mutation detected."
    },
    {
      "code": "PD-L1-POSITIVE",
      "display": "PD-L1 Positive",
      "definition": "PD-L1 expression ≥1%."
    },
    {
      "code": "PD-L1-NEGATIVE",
      "display": "PD-L1 Negative",
      "definition": "PD-L1 expression <1%."
    },
    {
      "code": "MSI-HIGH",
      "display": "MSI-High",
      "definition": "Microsatellite instability high."
    },
    {
      "code": "MSI-LOW",
      "display": "MSI-Low / MSS",
      "definition": "Microsatellite instability low or stable."
    },
    {
      "code": "EGFR-MUTANT",
      "display": "EGFR Mutant",
      "definition": "EGFR mutation detected."
    },
    {
      "code": "ALK-POSITIVE",
      "display": "ALK Positive",
      "definition": "ALK rearrangement detected."
    },
    {
      "code": "NOT-TESTED",
      "display": "Not Tested",
      "definition": "Biomarker testing not performed."
    }
  ]
}