FHIR IG Statistics: StructureDefinition/AllergyIntolerance_Eng.StructureDefinition

Resources that use this resource

No resources found

Resources that this resource uses

Narrative

No narrative content found in resource

Source

{
  "resourceType": "StructureDefinition",
  "url": "https://eng.it/fhir/StructureDefinition/AllergyIntolerance_Eng",
  "name": "AllergyIntolerance_Eng",
  "status": "draft",
  "date": "2023-02-16T09:14:40.7847492+00:00",
  "fhirVersion": "4.0.1",
  "kind": "resource",
  "abstract": false,
  "type": "AllergyIntolerance",
  "baseDefinition": "http://hl7.org/fhir/StructureDefinition/AllergyIntolerance",
  "derivation": "constraint",
  "snapshot": {
    "element": [
      {
        "id": "AllergyIntolerance",
        "path": "AllergyIntolerance",
        "short": "Allergy or Intolerance (generally: Risk of adverse reaction to a substance)",
        "definition": "Risk of harmful or undesirable, physiological response which is unique to an individual and associated with exposure to a substance.",
        "comment": "Substances include, but are not limited to: a therapeutic substance administered correctly at an appropriate dosage for the individual; food; material derived from plants or animals; or venom from insect stings.",
        "alias": [
          "Allergy",
          "Intolerance",
          "Adverse Reaction"
        ],
        "min": 0,
        "max": "*",
        "base": {
          "path": "AllergyIntolerance",
          "min": 0,
          "max": "*"
        },
        "constraint": [
          {
            "key": "dom-2",
            "severity": "error",
            "human": "If the resource is contained in another resource, it SHALL NOT contain nested Resources",
            "expression": "contained.contained.empty()",
            "xpath": "not(parent::f:contained and f:contained)",
            "source": "http://hl7.org/fhir/StructureDefinition/DomainResource"
          },
          {
            "key": "dom-4",
            "severity": "error",
            "human": "If a resource is contained in another resource, it SHALL NOT have a meta.versionId or a meta.lastUpdated",
            "expression": "contained.meta.versionId.empty() and contained.meta.lastUpdated.empty()",
            "xpath": "not(exists(f:contained/*/f:meta/f:versionId)) and not(exists(f:contained/*/f:meta/f:lastUpdated))",
            "source": "http://hl7.org/fhir/StructureDefinition/DomainResource"
          },
          {
            "key": "dom-3",
            "severity": "error",
            "human": "If the resource is contained in another resource, it SHALL be referred to from elsewhere in the resource or SHALL refer to the containing resource",
            "expression": "contained.where((('#'+id in (%resource.descendants().reference | %resource.descendants().as(canonical) | %resource.descendants().as(uri) | %resource.descendants().as(url))) or descendants().where(reference = '#').exists() or descendants().where(as(canonical) = '#').exists() or descendants().where(as(canonical) = '#').exists()).not()).trace('unmatched', id).empty()",
            "xpath": "not(exists(for $id in f:contained/*/f:id/@value return $contained[not(parent::*/descendant::f:reference/@value=concat('#', $contained/*/id/@value) or descendant::f:reference[@value='#'])]))",
            "source": "http://hl7.org/fhir/StructureDefinition/DomainResource"
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/elementdefinition-bestpractice",
                "valueBoolean": true
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/elementdefinition-bestpractice-explanation",
                "valueMarkdown": "When a resource has no narrative, only systems that fully understand the data can display the resource to a human safely. Including a human readable representation in the resource makes for a much more robust eco-system and cheaper handling of resources by intermediary systems. Some ecosystems restrict distribution of resources to only those systems that do fully understand the resources, and as a consequence implementers may believe that the narrative is superfluous. However experience shows that such eco-systems often open up to new participants over time."
              }
            ],
            "key": "dom-6",
            "severity": "warning",
            "human": "A resource should have narrative for robust management",
            "expression": "text.`div`.exists()",
            "xpath": "exists(f:text/h:div)",
            "source": "http://hl7.org/fhir/StructureDefinition/DomainResource"
          },
          {
            "key": "dom-5",
            "severity": "error",
            "human": "If a resource is contained in another resource, it SHALL NOT have a security label",
            "expression": "contained.meta.security.empty()",
            "xpath": "not(exists(f:contained/*/f:meta/f:security))",
            "source": "http://hl7.org/fhir/StructureDefinition/DomainResource"
          },
          {
            "key": "ait-1",
            "severity": "error",
            "human": "AllergyIntolerance.clinicalStatus SHALL be present if verificationStatus is not entered-in-error.",
            "expression": "verificationStatus.coding.where(system = 'http://terminology.hl7.org/CodeSystem/allergyintolerance-verification' and code = 'entered-in-error').exists() or clinicalStatus.exists()",
            "xpath": "f:verificationStatus/f:coding/f:code/@value='entered-in-error' or exists(f:clinicalStatus)",
            "source": "http://hl7.org/fhir/StructureDefinition/AllergyIntolerance"
          },
          {
            "key": "ait-2",
            "severity": "error",
            "human": "AllergyIntolerance.clinicalStatus SHALL NOT be present if verification Status is entered-in-error",
            "expression": "verificationStatus.coding.where(system = 'http://terminology.hl7.org/CodeSystem/allergyintolerance-verification' and code = 'entered-in-error').empty() or clinicalStatus.empty()",
            "xpath": "not(f:verificationStatus/f:coding/f:code/@value='entered-in-error') or not(exists(f:clinicalStatus))",
            "source": "http://hl7.org/fhir/StructureDefinition/AllergyIntolerance"
          }
        ],
        "mapping": [
          {
            "identity": "rim",
            "map": "Entity. Role, or Act"
          },
          {
            "identity": "rim",
            "map": "Observation[classCode=OBS, moodCode=EVN]"
          }
        ]
      },
      {
        "id": "AllergyIntolerance.id",
        "path": "AllergyIntolerance.id",
        "short": "Id logico di questo artefatto",
        "definition": "L'id logico della risorsa, utilizzato nell'URL della risorsa. Una volta assegnato, questo valore non cambia mai.",
        "comment": "L'unica volta che una risorsa non ha un id è quando viene inviata al server tramite un'operazione di creazione.",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Resource.id",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
                "valueUrl": "string"
              }
            ],
            "code": "http://hl7.org/fhirpath/System.String"
          }
        ],
        "isSummary": true
      },
      {
        "id": "AllergyIntolerance.meta",
        "extension": [
          {
            "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status",
            "valueCode": "normative"
          },
          {
            "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-normative-version",
            "valueCode": "4.0.0"
          }
        ],
        "path": "AllergyIntolerance.meta",
        "short": "Metadata about the resource",
        "definition": "The metadata about the resource. This is content that is maintained by the infrastructure. Changes to the content might not always be associated with version changes to the resource.",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Resource.meta",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "Meta"
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          }
        ],
        "isSummary": true,
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "rim",
            "map": "N/A"
          }
        ]
      },
      {
        "id": "AllergyIntolerance.implicitRules",
        "path": "AllergyIntolerance.implicitRules",
        "short": "A set of rules under which this content was created",
        "definition": "A reference to a set of rules that were followed when the resource was constructed, and which must be understood when processing the content. Often, this is a reference to an implementation guide that defines the special rules along with other profiles etc.",
        "comment": "Asserting this rule set restricts the content to be only understood by a limited set of trading partners. This inherently limits the usefulness of the data in the long term. However, the existing health eco-system is highly fractured, and not yet ready to define, collect, and exchange data in a generally computable sense. Wherever possible, implementers and/or specification writers should avoid using this element. Often, when used, the URL is a reference to an implementation guide that defines these special rules as part of it's narrative along with other profiles, value sets, etc.",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Resource.implicitRules",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "uri"
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          }
        ],
        "isModifier": true,
        "isModifierReason": "This element is labeled as a modifier because the implicit rules may provide additional knowledge about the resource that modifies it's meaning or interpretation",
        "isSummary": true,
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          }
        ]
      },
      {
        "id": "AllergyIntolerance.language",
        "path": "AllergyIntolerance.language",
        "short": "Language of the resource content",
        "definition": "The base language in which the resource is written.",
        "comment": "Language is provided to support indexing and accessibility (typically, services such as text to speech use the language tag). The html language tag in the narrative applies  to the narrative. The language tag on the resource may be used to specify the language of other presentations generated from the data in the resource. Not all the content has to be in the base language. The Resource.language should not be assumed to apply to the narrative automatically. If a language is specified, it should it also be specified on the div element in the html (see rules in HTML5 for information about the relationship between xml:lang and the html lang attribute).",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Resource.language",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "code"
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          }
        ],
        "binding": {
          "extension": [
            {
              "url": "http://hl7.org/fhir/StructureDefinition/elementdefinition-maxValueSet",
              "valueCanonical": "http://hl7.org/fhir/ValueSet/all-languages"
            },
            {
              "url": "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName",
              "valueString": "Language"
            },
            {
              "url": "http://hl7.org/fhir/StructureDefinition/elementdefinition-isCommonBinding",
              "valueBoolean": true
            }
          ],
          "strength": "preferred",
          "description": "A human language.",
          "valueSet": "http://hl7.org/fhir/ValueSet/languages"
        },
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          }
        ]
      },
      {
        "id": "AllergyIntolerance.text",
        "extension": [
          {
            "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status",
            "valueCode": "normative"
          },
          {
            "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-normative-version",
            "valueCode": "4.0.0"
          }
        ],
        "path": "AllergyIntolerance.text",
        "short": "Text summary of the resource, for human interpretation",
        "definition": "A human-readable narrative that contains a summary of the resource and can be used to represent the content of the resource to a human. The narrative need not encode all the structured data, but is required to contain sufficient detail to make it \"clinically safe\" for a human to just read the narrative. Resource definitions may define what content should be represented in the narrative to ensure clinical safety.",
        "comment": "Contained resources do not have narrative. Resources that are not contained SHOULD have a narrative. In some cases, a resource may only have text with little or no additional discrete data (as long as all minOccurs=1 elements are satisfied).  This may be necessary for data from legacy systems where information is captured as a \"text blob\" or where text is additionally entered raw or narrated and encoded information is added later.",
        "alias": [
          "narrative",
          "html",
          "xhtml",
          "display"
        ],
        "min": 0,
        "max": "1",
        "base": {
          "path": "DomainResource.text",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "Narrative"
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          }
        ],
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "rim",
            "map": "N/A"
          },
          {
            "identity": "rim",
            "map": "Act.text?"
          }
        ]
      },
      {
        "id": "AllergyIntolerance.contained",
        "path": "AllergyIntolerance.contained",
        "short": "Contained, inline Resources",
        "definition": "These resources do not have an independent existence apart from the resource that contains them - they cannot be identified independently, and nor can they have their own independent transaction scope.",
        "comment": "This should never be done when the content can be identified properly, as once identification is lost, it is extremely difficult (and context dependent) to restore it again. Contained resources may have profiles and tags In their meta elements, but SHALL NOT have security labels.",
        "alias": [
          "inline resources",
          "anonymous resources",
          "contained resources"
        ],
        "min": 0,
        "max": "*",
        "base": {
          "path": "DomainResource.contained",
          "min": 0,
          "max": "*"
        },
        "type": [
          {
            "code": "Resource"
          }
        ],
        "mapping": [
          {
            "identity": "rim",
            "map": "Entity. Role, or Act"
          },
          {
            "identity": "rim",
            "map": "N/A"
          }
        ]
      },
      {
        "id": "AllergyIntolerance.extension",
        "extension": [
          {
            "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status",
            "valueCode": "normative"
          },
          {
            "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-normative-version",
            "valueCode": "4.0.0"
          }
        ],
        "path": "AllergyIntolerance.extension",
        "slicing": {
          "discriminator": [
            {
              "type": "value",
              "path": "url"
            }
          ],
          "description": "Extensions are always sliced by (at least) url",
          "rules": "open"
        },
        "short": "Additional content defined by implementations",
        "definition": "May be used to represent additional information that is not part of the basic definition of the resource. To make the use of extensions safe and manageable, there is a strict set of governance  applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.",
        "comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
        "alias": [
          "extensions",
          "user content"
        ],
        "min": 0,
        "max": "*",
        "base": {
          "path": "DomainResource.extension",
          "min": 0,
          "max": "*"
        },
        "type": [
          {
            "code": "Extension"
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          },
          {
            "key": "ext-1",
            "severity": "error",
            "human": "Must have either extensions or value[x], not both",
            "expression": "extension.exists() != value.exists()",
            "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), 'value')])",
            "source": "http://hl7.org/fhir/StructureDefinition/Extension"
          }
        ],
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "rim",
            "map": "N/A"
          }
        ]
      },
      {
        "id": "AllergyIntolerance.modifierExtension",
        "extension": [
          {
            "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status",
            "valueCode": "normative"
          },
          {
            "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-normative-version",
            "valueCode": "4.0.0"
          }
        ],
        "path": "AllergyIntolerance.modifierExtension",
        "slicing": {
          "discriminator": [
            {
              "type": "value",
              "path": "url"
            }
          ],
          "description": "Extensions are always sliced by (at least) url",
          "rules": "open"
        },
        "short": "Extensions that cannot be ignored",
        "definition": "May be used to represent additional information that is not part of the basic definition of the resource and that modifies the understanding of the element that contains it and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer is allowed to define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.\n\nModifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).",
        "comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
        "requirements": "Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored.  This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](extensibility.html#modifierExtension).",
        "alias": [
          "extensions",
          "user content"
        ],
        "min": 0,
        "max": "*",
        "base": {
          "path": "DomainResource.modifierExtension",
          "min": 0,
          "max": "*"
        },
        "type": [
          {
            "code": "Extension"
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          },
          {
            "key": "ext-1",
            "severity": "error",
            "human": "Must have either extensions or value[x], not both",
            "expression": "extension.exists() != value.exists()",
            "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), 'value')])",
            "source": "http://hl7.org/fhir/StructureDefinition/Extension"
          }
        ],
        "isModifier": true,
        "isModifierReason": "Modifier extensions are expected to modify the meaning or interpretation of the resource that contains them",
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "rim",
            "map": "N/A"
          }
        ]
      },
      {
        "id": "AllergyIntolerance.identifier",
        "extension": [
          {
            "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status",
            "valueCode": "normative"
          },
          {
            "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-normative-version",
            "valueCode": "4.0.0"
          }
        ],
        "path": "AllergyIntolerance.identifier",
        "short": "External ids for this item",
        "definition": "Business identifiers assigned to this AllergyIntolerance by the performer or other systems which remain constant as the resource is updated and propagates from server to server.",
        "comment": "This is a business identifier, not a resource identifier (see [discussion](resource.html#identifiers)).  It is best practice for the identifier to only appear on a single resource instance, however business practices may occasionally dictate that multiple resource instances with the same identifier can exist - possibly even with different resource types.  For example, multiple Patient and a Person resource instance might share the same social insurance number.",
        "requirements": "Allows identification of the AllergyIntolerance as it is known by various participating systems and in a way that remains consistent across servers.",
        "min": 0,
        "max": "*",
        "base": {
          "path": "AllergyIntolerance.identifier",
          "min": 0,
          "max": "*"
        },
        "type": [
          {
            "code": "Identifier"
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          }
        ],
        "isSummary": true,
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "v2",
            "map": "CX / EI (occasionally, more often EI maps to a resource id or a URL)"
          },
          {
            "identity": "rim",
            "map": "II - The Identifier class is a little looser than the v3 type II because it allows URIs as well as registered OIDs or GUIDs.  Also maps to Role[classCode=IDENT]"
          },
          {
            "identity": "servd",
            "map": "Identifier"
          },
          {
            "identity": "w5",
            "map": "FiveWs.identifier"
          },
          {
            "identity": "v2",
            "map": "IAM-7"
          },
          {
            "identity": "rim",
            "map": "id"
          }
        ]
      },
      {
        "id": "AllergyIntolerance.clinicalStatus",
        "extension": [
          {
            "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status",
            "valueCode": "normative"
          },
          {
            "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-normative-version",
            "valueCode": "4.0.0"
          }
        ],
        "path": "AllergyIntolerance.clinicalStatus",
        "short": "active | inactive | resolved",
        "definition": "The clinical status of the allergy or intolerance.",
        "comment": "Refer to [discussion](extensibility.html#Special-Case) if clincalStatus is missing data.\nThe data type is CodeableConcept because clinicalStatus has some clinical judgment involved, such that there might need to be more specificity than the required FHIR value set allows. For example, a SNOMED coding might allow for additional specificity.",
        "min": 0,
        "max": "1",
        "base": {
          "path": "AllergyIntolerance.clinicalStatus",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "CodeableConcept"
          }
        ],
        "condition": [
          "ele-1",
          "ait-1",
          "ait-2"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          }
        ],
        "isModifier": true,
        "isModifierReason": "This element is labeled as a modifier because the status contains the codes inactive and resolved that mark the AllergyIntolerance as no longer active.",
        "isSummary": true,
        "binding": {
          "extension": [
            {
              "url": "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName",
              "valueString": "AllergyIntoleranceClinicalStatus"
            }
          ],
          "strength": "required",
          "description": "The clinical status of the allergy or intolerance.",
          "valueSet": "http://hl7.org/fhir/ValueSet/allergyintolerance-clinical|4.0.1"
        },
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "v2",
            "map": "CE/CNE/CWE"
          },
          {
            "identity": "rim",
            "map": "CD"
          },
          {
            "identity": "orim",
            "map": "fhir:CodeableConcept rdfs:subClassOf dt:CD"
          },
          {
            "identity": "w5",
            "map": "FiveWs.status"
          },
          {
            "identity": "rim",
            "map": "Observation ACT .inboundRelationship[typeCode=COMP].source[classCode=OBS, code=\"clinicalStatus\", moodCode=EVN].value"
          }
        ]
      },
      {
        "id": "AllergyIntolerance.verificationStatus",
        "extension": [
          {
            "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status",
            "valueCode": "normative"
          },
          {
            "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-normative-version",
            "valueCode": "4.0.0"
          }
        ],
        "path": "AllergyIntolerance.verificationStatus",
        "short": "unconfirmed | confirmed | refuted | entered-in-error",
        "definition": "Assertion about certainty associated with the propensity, or potential risk, of a reaction to the identified substance (including pharmaceutical product).",
        "comment": "The data type is CodeableConcept because verificationStatus has some clinical judgment involved, such that there might need to be more specificity than the required FHIR value set allows. For example, a SNOMED coding might allow for additional specificity.",
        "min": 0,
        "max": "1",
        "base": {
          "path": "AllergyIntolerance.verificationStatus",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "CodeableConcept"
          }
        ],
        "condition": [
          "ele-1",
          "ait-1",
          "ait-2"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          }
        ],
        "isModifier": true,
        "isModifierReason": "This element is labeled as a modifier because the status contains the codes refuted and entered-in-error that mark the AllergyIntolerance as not currently valid.",
        "isSummary": true,
        "binding": {
          "extension": [
            {
              "url": "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName",
              "valueString": "AllergyIntoleranceVerificationStatus"
            }
          ],
          "strength": "required",
          "description": "Assertion about certainty associated with a propensity, or potential risk, of a reaction to the identified substance.",
          "valueSet": "http://hl7.org/fhir/ValueSet/allergyintolerance-verification|4.0.1"
        },
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "v2",
            "map": "CE/CNE/CWE"
          },
          {
            "identity": "rim",
            "map": "CD"
          },
          {
            "identity": "orim",
            "map": "fhir:CodeableConcept rdfs:subClassOf dt:CD"
          },
          {
            "identity": "w5",
            "map": "FiveWs.status"
          },
          {
            "identity": "rim",
            "map": "Observation ACT .inboundRelationship[typeCode=COMP].source[classCode=OBS, code=\"verificationStatus\", moodCode=EVN].value"
          }
        ]
      },
      {
        "id": "AllergyIntolerance.type",
        "path": "AllergyIntolerance.type",
        "short": "Allergia o intolleranza",
        "definition": "Identificazione del meccanismo fisiologico alla base del rischio di reazione.\r\n\r\nValori ammessi:\r\n\r\n* allergy: Propensione a reazioni di ipersensibilità a una sostanza. Queste reazioni sono in genere l'ipersensibilità di tipo I e altre reazioni \"allergiche\", tra cui la pseudoallergia.\r\n\r\n* intolerance: Una propensione a reazioni avverse a una sostanza che non è giudicata allergica o \"simile all'allergia\". Queste reazioni sono tipicamente (ma non necessariamente) non immunitarie. Sono in qualche misura idiosincratiche e/o specifiche per il paziente (cioè non sono una reazione che ci si aspetta si verifichi nella maggior parte o in tutti i pazienti in circostanze simili).",
        "comment": "Le reazioni allergiche (tipicamente immuno-mediate) sono state tradizionalmente considerate un indicatore di potenziale escalation verso un rischio futuro significativo. Le conoscenze attuali suggeriscono che alcune reazioni precedentemente ritenute immuno-mediate sono, in realtà, non immuni, ma in alcuni casi possono ancora rappresentare un rischio per la vita. Si riconosce che molti medici potrebbero non essere in grado di distinguere il meccanismo di una particolare reazione. Spesso il termine \"allergia\" è usato in modo piuttosto generico e può sovrapporsi all'uso di \"intolleranza\" - in pratica i confini tra questi due concetti potrebbero non essere ben definiti o compresi. Questo dato viene comunque incluso perché molti sistemi preesistenti hanno rilevato questo attributo. I test immunologici possono fornire prove a sostegno della base della reazione e della sostanza causale, ma nessun test è sensibile o specifico al 100% per la sensibilità a una particolare sostanza. Se, come spesso accade, non è chiaro se la reazione sia dovuta a un'allergia o a un'intolleranza, l'elemento type deve essere omesso dalla risorsa.",
        "alias": [
          "Category",
          "Class"
        ],
        "min": 0,
        "max": "1",
        "base": {
          "path": "AllergyIntolerance.type",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "code"
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          }
        ],
        "isSummary": true,
        "binding": {
          "extension": [
            {
              "url": "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName",
              "valueString": "AllergyIntoleranceType"
            }
          ],
          "strength": "required",
          "description": "Identification of the underlying physiological mechanism for a Reaction Risk.",
          "valueSet": "http://hl7.org/fhir/ValueSet/allergy-intolerance-type|4.0.1"
        },
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "w5",
            "map": "FiveWs.class"
          },
          {
            "identity": "v2",
            "map": "IAM-9"
          },
          {
            "identity": "rim",
            "map": "code"
          }
        ]
      },
      {
        "id": "AllergyIntolerance.category",
        "path": "AllergyIntolerance.category",
        "short": "food | medication | environment | biologic",
        "definition": "Categoria della sostanza identificata.\r\n\r\nValori ammessi: \r\n\r\n* food: Qualsiasi sostanza consumata per fornire un supporto nutrizionale all'organismo.\r\n\r\n* medication: Sostanze somministrate per ottenere un effetto fisiologico.\r\n\r\n* environment: Tutte le sostanze presenti nell'ambiente, comprese quelle non già classificate come alimenti, farmaci o sostanze biologiche.\r\n\r\n* biologic: Un preparato sintetizzato da organismi viventi o dai loro prodotti, in particolare una proteina umana o animale, come un ormone o un'antitossina, utilizzato come agente diagnostico, preventivo o terapeutico. Esempi di farmaci biologici sono: i vaccini; gli estratti allergenici, utilizzati sia per la diagnosi che per il trattamento (ad esempio, le iniezioni di allergia); le terapie geniche; le terapie cellulari. Esistono altri prodotti biologici, come i tessuti, che non sono tipicamente associati alle allergie.",
        "comment": "Questo dato è stato incluso perché attualmente viene rilevato in alcuni sistemi clinici. Questo dato può essere ricavato dalla sostanza in cui si utilizzano sistemi di codifica ed è effettivamente ridondante in tale situazione.  Quando si effettua una ricerca per categoria, considerare le implicazioni delle risorse Allergia-Intolleranza senza categoria.  Ad esempio, quando si effettua una ricerca su categoria = farmaco, le allergie ai farmaci che non hanno una categoria valorizzata non verranno restituite.  Fare riferimento a [search](search.html) per maggiori informazioni su come cercare la categoria con un modificatore :missing per ottenere le allergie che non hanno una categoria.  Inoltre, la categoria deve essere usata con cautela perché può essere soggettiva a seconda del mittente.",
        "alias": [
          "Category",
          "Type",
          "Reaction Type",
          "Class"
        ],
        "min": 0,
        "max": "*",
        "base": {
          "path": "AllergyIntolerance.category",
          "min": 0,
          "max": "*"
        },
        "type": [
          {
            "code": "code"
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          }
        ],
        "isSummary": true,
        "binding": {
          "extension": [
            {
              "url": "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName",
              "valueString": "AllergyIntoleranceCategory"
            }
          ],
          "strength": "required",
          "description": "Category of an identified substance associated with allergies or intolerances.",
          "valueSet": "http://hl7.org/fhir/ValueSet/allergy-intolerance-category|4.0.1"
        },
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "w5",
            "map": "FiveWs.class"
          },
          {
            "identity": "v2",
            "map": "AL1-2"
          },
          {
            "identity": "rim",
            "map": "value < IntoleranceValue (Agent)"
          }
        ]
      },
      {
        "id": "AllergyIntolerance.criticality",
        "path": "AllergyIntolerance.criticality",
        "short": "low | high | unable-to-assess",
        "definition": "Estimate of the potential clinical harm, or seriousness, of the reaction to the identified substance.",
        "comment": "The default criticality value for any propensity to an adverse reaction should be 'Low Risk', indicating at the very least a relative contraindication to deliberate or voluntary exposure to the substance. 'High Risk' is flagged if the clinician has identified a propensity for a more serious or potentially life-threatening reaction, such as anaphylaxis, and implies an absolute contraindication to deliberate or voluntary exposure to the substance. If this element is missing, the criticality is unknown (though it may be known elsewhere).  Systems that capture a severity at the condition level are actually representing the concept of criticality whereas the severity documented at the reaction level is representing the true reaction severity.  Existing systems that are capturing both condition criticality and reaction severity may use the term \"severity\" to represent both.  Criticality is the worst it could be in the future (i.e. situation-agnostic) whereas severity is situation-dependent.",
        "alias": [
          "Severity",
          "Seriousness",
          "Contra-indication",
          "Risk"
        ],
        "min": 0,
        "max": "1",
        "base": {
          "path": "AllergyIntolerance.criticality",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "code"
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          }
        ],
        "isSummary": true,
        "binding": {
          "extension": [
            {
              "url": "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName",
              "valueString": "AllergyIntoleranceCriticality"
            }
          ],
          "strength": "required",
          "description": "Estimate of the potential clinical harm, or seriousness, of a reaction to an identified substance.",
          "valueSet": "http://hl7.org/fhir/ValueSet/allergy-intolerance-criticality|4.0.1"
        },
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "w5",
            "map": "FiveWs.grade"
          },
          {
            "identity": "v2",
            "map": "AL1-4"
          },
          {
            "identity": "rim",
            "map": "inboundRelationship[typeCode=SUBJ].source[classCode=OBS, moodCode=EVN, code=SEV, value <= SeverityObservation (Severity Level)]"
          }
        ]
      },
      {
        "id": "AllergyIntolerance.code",
        "extension": [
          {
            "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status",
            "valueCode": "normative"
          },
          {
            "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-normative-version",
            "valueCode": "4.0.0"
          }
        ],
        "path": "AllergyIntolerance.code",
        "short": "Codice che identifica l'allergia o l'intolleranza",
        "definition": "Codice per una dichiarazione di allergia o intolleranza (positiva o negata/esclusa).  \r\n\r\nPuò trattarsi di un codice per una sostanza o un prodotto farmaceutico considerato responsabile del rischio di reazione avversa (ad esempio, \"Lattice\"), di una condizione di allergia o intolleranza (ad esempio, \"Allergia al lattice\"), o di un codice negato/escluso per una sostanza o una classe specifica (ad esempio, \"Nessuna allergia al lattice\") o di una dichiarazione negata generale o categorica (ad esempio, \"Nessuna allergia nota\", \"Nessuna allergia nota ai farmaci\").\r\n\r\nNota: la sostanza per una reazione specifica può essere diversa dalla sostanza identificata come causa del rischio, ma deve essere coerente con essa. Ad esempio, può trattarsi di una sostanza più specifica (ad esempio un farmaco di marca) o di un prodotto composito che include la sostanza identificata. Deve essere clinicamente sicuro elaborare solo il \"codice\" e ignorare la \"reazione.sostanza\".  Se un sistema ricevente non è in grado di confermare che AllergyIntolerance.reaction.substance rientra nell'ambito semantico di AllergyIntolerance.code, allora il sistema ricevente deve ignorare AllergyIntolerance.reaction.substance.",
        "comment": "Si raccomanda vivamente che questo elemento sia popolato utilizzando una terminologia, ove possibile. Ad esempio, alcune terminologie utilizzate sono RxNorm, SNOMED CT, DM+D, NDFRT, ICD-9, IDC-10, UNII e ATC. Il testo semplice deve essere utilizzato solo se non è disponibile una terminologia appropriata. Ulteriori dettagli possono essere specificati nel testo.\r\n\r\nQuando viene specificato un codice di sostanza o prodotto per l'elemento \"codice\", il contesto semantico \"predefinito\" è che si tratta di una dichiarazione positiva di una condizione di allergia o intolleranza (a seconda del valore dell'elemento \"tipo\", se presente) alla sostanza/prodotto specificato.  Nel corrispondente modello SNOMED CT di allergia, la sostanza/prodotto specificato è il target (destinazione) della relazione \"agente causale\".\r\n\r\nL'estensione \"substanceExposureRisk\" è disponibile come alternativa strutturata e più flessibile all'elemento \"code\" per la formulazione di dichiarazioni di allergia o intolleranza positive o negative.  Questa estensione offre la possibilità di fare dichiarazioni di \"nessuna allergia nota\" (o \"nessun rischio di reazione avversa\") in merito a qualsiasi sostanza/prodotto codificato (compresi i casi in cui non esiste un concetto precoordinato di \"nessuna allergia a x\" per quella sostanza/prodotto).  Se è presente l'estensione \"substanceExposureRisk\", l'elemento AllergyIntolerance.code DEVE essere omesso.",
        "alias": [
          "Code"
        ],
        "min": 0,
        "max": "1",
        "base": {
          "path": "AllergyIntolerance.code",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "CodeableConcept"
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          }
        ],
        "isSummary": true,
        "binding": {
          "extension": [
            {
              "url": "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName",
              "valueString": "AllergyIntoleranceCode"
            }
          ],
          "strength": "example",
          "description": "Type of the substance/product, allergy or intolerance condition, or negation/exclusion codes for reporting no known allergies.",
          "valueSet": "http://hl7.org/fhir/ValueSet/allergyintolerance-code"
        },
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "v2",
            "map": "CE/CNE/CWE"
          },
          {
            "identity": "rim",
            "map": "CD"
          },
          {
            "identity": "orim",
            "map": "fhir:CodeableConcept rdfs:subClassOf dt:CD"
          },
          {
            "identity": "w5",
            "map": "FiveWs.what[x]"
          },
          {
            "identity": "v2",
            "map": "AL1-3 / IAM-3"
          },
          {
            "identity": "rim",
            "map": "substance/product:\r\r.participation[typeCode=CAGNT].role[classCode=ADMM].player[classCode=MAT, determinerCode=KIND, code <= ExposureAgentEntityType]\r\rnegated/excluded substance/product:\r\r.participation[typeCode=CAGNT, negationInd=true].role[classCode=ADMM].player[classCode=MAT, determinerCode=KIND, code <= ExposureAgentEntityType]\r\rpositive or negated/excluded condition/situation:\r\rObservation.code=ASSERTION; Observation.value"
          }
        ]
      },
      {
        "id": "AllergyIntolerance.code.id",
        "path": "AllergyIntolerance.code.id",
        "representation": [
          "xmlAttr"
        ],
        "short": "Unique id for inter-element referencing",
        "definition": "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Element.id",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
                "valueUrl": "string"
              }
            ],
            "code": "http://hl7.org/fhirpath/System.String"
          }
        ],
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          }
        ]
      },
      {
        "id": "AllergyIntolerance.code.extension",
        "extension": [
          {
            "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status",
            "valueCode": "normative"
          },
          {
            "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-normative-version",
            "valueCode": "4.0.0"
          }
        ],
        "path": "AllergyIntolerance.code.extension",
        "slicing": {
          "discriminator": [
            {
              "type": "value",
              "path": "url"
            }
          ],
          "description": "Extensions are always sliced by (at least) url",
          "rules": "open"
        },
        "short": "Additional content defined by implementations",
        "definition": "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance  applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.",
        "comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
        "alias": [
          "extensions",
          "user content"
        ],
        "min": 0,
        "max": "*",
        "base": {
          "path": "Element.extension",
          "min": 0,
          "max": "*"
        },
        "type": [
          {
            "code": "Extension"
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          },
          {
            "key": "ext-1",
            "severity": "error",
            "human": "Must have either extensions or value[x], not both",
            "expression": "extension.exists() != value.exists()",
            "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), 'value')])",
            "source": "http://hl7.org/fhir/StructureDefinition/Extension"
          }
        ],
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "rim",
            "map": "N/A"
          }
        ]
      },
      {
        "id": "AllergyIntolerance.code.coding",
        "extension": [
          {
            "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status",
            "valueCode": "normative"
          },
          {
            "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-normative-version",
            "valueCode": "4.0.0"
          }
        ],
        "path": "AllergyIntolerance.code.coding",
        "slicing": {
          "discriminator": [
            {
              "type": "value",
              "path": "system"
            }
          ],
          "rules": "closed"
        },
        "short": "Codice definito da un sistema terminologico",
        "definition": "Un riferimento a un codice definito da un sistema terminologico.",
        "comment": "I codici possono essere definiti in modo molto casuale in enumerazioni o elenchi di codici, fino a definizioni molto formali come SNOMED CT - si vedano i Core Principles di HL7 v3 per maggiori informazioni.  L'ordine dei codici non è definito e NON DEVE essere usato per dedurre il significato. In generale, al massimo uno solo dei valori di codifica sarà etichettato come UserSelected = true.",
        "requirements": "Allows for alternative encodings within a code system, and translations to other code systems.",
        "min": 0,
        "max": "*",
        "base": {
          "path": "CodeableConcept.coding",
          "min": 0,
          "max": "*"
        },
        "type": [
          {
            "code": "Coding"
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          }
        ],
        "isSummary": true,
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "v2",
            "map": "CE/CNE/CWE subset one of the sets of component 1-3 or 4-6"
          },
          {
            "identity": "rim",
            "map": "CV"
          },
          {
            "identity": "orim",
            "map": "fhir:Coding rdfs:subClassOf dt:CDCoding"
          },
          {
            "identity": "v2",
            "map": "C*E.1-8, C*E.10-22"
          },
          {
            "identity": "rim",
            "map": "union(., ./translation)"
          },
          {
            "identity": "orim",
            "map": "fhir:CodeableConcept.coding rdfs:subPropertyOf dt:CD.coding"
          }
        ]
      },
      {
        "id": "AllergyIntolerance.code.coding:medicationKnowledge-substance",
        "extension": [
          {
            "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status",
            "valueCode": "normative"
          },
          {
            "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-normative-version",
            "valueCode": "4.0.0"
          }
        ],
        "path": "AllergyIntolerance.code.coding",
        "sliceName": "medicationKnowledge-substance",
        "short": "Codice definito da un sistema terminologico",
        "definition": "Un riferimento a un codice definito da un sistema terminologico.",
        "comment": "I codici possono essere definiti in modo molto casuale in enumerazioni o elenchi di codici, fino a definizioni molto formali come SNOMED CT - si vedano i Core Principles di HL7 v3 per maggiori informazioni.  L'ordine dei codici non è definito e NON DEVE essere usato per dedurre il significato. In generale, al massimo uno solo dei valori di codifica sarà etichettato come UserSelected = true.",
        "requirements": "Allows for alternative encodings within a code system, and translations to other code systems.",
        "min": 0,
        "max": "*",
        "base": {
          "path": "CodeableConcept.coding",
          "min": 0,
          "max": "*"
        },
        "type": [
          {
            "code": "Coding"
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          }
        ],
        "isSummary": true,
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "v2",
            "map": "CE/CNE/CWE subset one of the sets of component 1-3 or 4-6"
          },
          {
            "identity": "rim",
            "map": "CV"
          },
          {
            "identity": "orim",
            "map": "fhir:Coding rdfs:subClassOf dt:CDCoding"
          },
          {
            "identity": "v2",
            "map": "C*E.1-8, C*E.10-22"
          },
          {
            "identity": "rim",
            "map": "union(., ./translation)"
          },
          {
            "identity": "orim",
            "map": "fhir:CodeableConcept.coding rdfs:subPropertyOf dt:CD.coding"
          }
        ]
      },
      {
        "id": "AllergyIntolerance.code.coding:medicationKnowledge-substance.id",
        "path": "AllergyIntolerance.code.coding.id",
        "representation": [
          "xmlAttr"
        ],
        "short": "Unique id for inter-element referencing",
        "definition": "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Element.id",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
                "valueUrl": "string"
              }
            ],
            "code": "http://hl7.org/fhirpath/System.String"
          }
        ],
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          }
        ]
      },
      {
        "id": "AllergyIntolerance.code.coding:medicationKnowledge-substance.extension",
        "extension": [
          {
            "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status",
            "valueCode": "normative"
          },
          {
            "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-normative-version",
            "valueCode": "4.0.0"
          }
        ],
        "path": "AllergyIntolerance.code.coding.extension",
        "slicing": {
          "discriminator": [
            {
              "type": "value",
              "path": "url"
            }
          ],
          "description": "Extensions are always sliced by (at least) url",
          "rules": "open"
        },
        "short": "Additional content defined by implementations",
        "definition": "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance  applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.",
        "comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
        "alias": [
          "extensions",
          "user content"
        ],
        "min": 0,
        "max": "*",
        "base": {
          "path": "Element.extension",
          "min": 0,
          "max": "*"
        },
        "type": [
          {
            "code": "Extension"
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          },
          {
            "key": "ext-1",
            "severity": "error",
            "human": "Must have either extensions or value[x], not both",
            "expression": "extension.exists() != value.exists()",
            "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), 'value')])",
            "source": "http://hl7.org/fhir/StructureDefinition/Extension"
          }
        ],
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "rim",
            "map": "N/A"
          }
        ]
      },
      {
        "id": "AllergyIntolerance.code.coding:medicationKnowledge-substance.system",
        "path": "AllergyIntolerance.code.coding.system",
        "short": "Identità del sistema terminologico",
        "definition": "L'identificazione del sistema di codice che definisce il significato del simbolo nel codice.",
        "comment": "L'URI può essere un OID (urn:oid:...) o un UUID (urn:uuid:...).  Gli OID e gli UUID DEVONO essere riferimenti al registro OID di HL7. Altrimenti, l'URI deve provenire dall'elenco di URI speciali definiti da HL7 per FHIR o deve fare riferimento a qualche definizione che stabilisca il sistema in modo chiaro e non ambiguo.",
        "requirements": "Need to be unambiguous about the source of the definition of the symbol.",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Coding.system",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "uri"
          }
        ],
        "fixedUri": "http://farmadati.eng.it/FHIR/schema/medicationKnowledge-substance",
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          }
        ],
        "isSummary": true,
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "v2",
            "map": "C*E.3"
          },
          {
            "identity": "rim",
            "map": "./codeSystem"
          },
          {
            "identity": "orim",
            "map": "fhir:Coding.system rdfs:subPropertyOf dt:CDCoding.codeSystem"
          }
        ]
      },
      {
        "id": "AllergyIntolerance.code.coding:medicationKnowledge-substance.version",
        "path": "AllergyIntolerance.code.coding.version",
        "short": "Version of the system - if relevant",
        "definition": "The version of the code system which was used when choosing this code. Note that a well-maintained code system does not need the version reported, because the meaning of codes is consistent across versions. However this cannot consistently be assured, and when the meaning is not guaranteed to be consistent, the version SHOULD be exchanged.",
        "comment": "Where the terminology does not clearly define what string should be used to identify code system versions, the recommendation is to use the date (expressed in FHIR date format) on which that version was officially published as the version date.",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Coding.version",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "string"
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          }
        ],
        "isSummary": true,
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "v2",
            "map": "C*E.7"
          },
          {
            "identity": "rim",
            "map": "./codeSystemVersion"
          },
          {
            "identity": "orim",
            "map": "fhir:Coding.version rdfs:subPropertyOf dt:CDCoding.codeSystemVersion"
          }
        ]
      },
      {
        "id": "AllergyIntolerance.code.coding:medicationKnowledge-substance.code",
        "path": "AllergyIntolerance.code.coding.code",
        "short": "Symbol in syntax defined by the system",
        "definition": "A symbol in syntax defined by the system. The symbol may be a predefined code or an expression in a syntax defined by the coding system (e.g. post-coordination).",
        "comment": "Note that FHIR strings SHALL NOT exceed 1MB in size",
        "requirements": "Need to refer to a particular code in the system.",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Coding.code",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "code"
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          }
        ],
        "isSummary": true,
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "v2",
            "map": "C*E.1"
          },
          {
            "identity": "rim",
            "map": "./code"
          },
          {
            "identity": "orim",
            "map": "fhir:Coding.code rdfs:subPropertyOf dt:CDCoding.code"
          }
        ]
      },
      {
        "id": "AllergyIntolerance.code.coding:medicationKnowledge-substance.display",
        "extension": [
          {
            "url": "http://hl7.org/fhir/StructureDefinition/elementdefinition-translatable",
            "valueBoolean": true
          }
        ],
        "path": "AllergyIntolerance.code.coding.display",
        "short": "Representation defined by the system",
        "definition": "A representation of the meaning of the code in the system, following the rules of the system.",
        "comment": "Note that FHIR strings SHALL NOT exceed 1MB in size",
        "requirements": "Need to be able to carry a human-readable meaning of the code for readers that do not know  the system.",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Coding.display",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "string"
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          }
        ],
        "isSummary": true,
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "v2",
            "map": "C*E.2 - but note this is not well followed"
          },
          {
            "identity": "rim",
            "map": "CV.displayName"
          },
          {
            "identity": "orim",
            "map": "fhir:Coding.display rdfs:subPropertyOf dt:CDCoding.displayName"
          }
        ]
      },
      {
        "id": "AllergyIntolerance.code.coding:medicationKnowledge-substance.userSelected",
        "path": "AllergyIntolerance.code.coding.userSelected",
        "short": "If this coding was chosen directly by the user",
        "definition": "Indicates that this coding was chosen by a user directly - e.g. off a pick list of available items (codes or displays).",
        "comment": "Amongst a set of alternatives, a directly chosen code is the most appropriate starting point for new translations. There is some ambiguity about what exactly 'directly chosen' implies, and trading partner agreement may be needed to clarify the use of this element and its consequences more completely.",
        "requirements": "This has been identified as a clinical safety criterium - that this exact system/code pair was chosen explicitly, rather than inferred by the system based on some rules or language processing.",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Coding.userSelected",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "boolean"
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          }
        ],
        "isSummary": true,
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "v2",
            "map": "Sometimes implied by being first"
          },
          {
            "identity": "rim",
            "map": "CD.codingRationale"
          },
          {
            "identity": "orim",
            "map": "fhir:Coding.userSelected fhir:mapsTo dt:CDCoding.codingRationale. fhir:Coding.userSelected fhir:hasMap fhir:Coding.userSelected.map. fhir:Coding.userSelected.map a fhir:Map;   fhir:target dt:CDCoding.codingRationale. fhir:Coding.userSelected\\#true a [     fhir:source \"true\";     fhir:target dt:CDCoding.codingRationale\\#O   ]"
          }
        ]
      },
      {
        "id": "AllergyIntolerance.code.coding:atc",
        "extension": [
          {
            "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status",
            "valueCode": "normative"
          },
          {
            "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-normative-version",
            "valueCode": "4.0.0"
          }
        ],
        "path": "AllergyIntolerance.code.coding",
        "sliceName": "atc",
        "short": "Codice definito da un sistema terminologico",
        "definition": "Un riferimento a un codice definito da un sistema terminologico.",
        "comment": "I codici possono essere definiti in modo molto casuale in enumerazioni o elenchi di codici, fino a definizioni molto formali come SNOMED CT - si vedano i Core Principles di HL7 v3 per maggiori informazioni.  L'ordine dei codici non è definito e NON DEVE essere usato per dedurre il significato. In generale, al massimo uno solo dei valori di codifica sarà etichettato come UserSelected = true.",
        "requirements": "Allows for alternative encodings within a code system, and translations to other code systems.",
        "min": 0,
        "max": "*",
        "base": {
          "path": "CodeableConcept.coding",
          "min": 0,
          "max": "*"
        },
        "type": [
          {
            "code": "Coding"
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          }
        ],
        "isSummary": true,
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "v2",
            "map": "CE/CNE/CWE subset one of the sets of component 1-3 or 4-6"
          },
          {
            "identity": "rim",
            "map": "CV"
          },
          {
            "identity": "orim",
            "map": "fhir:Coding rdfs:subClassOf dt:CDCoding"
          },
          {
            "identity": "v2",
            "map": "C*E.1-8, C*E.10-22"
          },
          {
            "identity": "rim",
            "map": "union(., ./translation)"
          },
          {
            "identity": "orim",
            "map": "fhir:CodeableConcept.coding rdfs:subPropertyOf dt:CD.coding"
          }
        ]
      },
      {
        "id": "AllergyIntolerance.code.coding:atc.id",
        "path": "AllergyIntolerance.code.coding.id",
        "representation": [
          "xmlAttr"
        ],
        "short": "Unique id for inter-element referencing",
        "definition": "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Element.id",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
                "valueUrl": "string"
              }
            ],
            "code": "http://hl7.org/fhirpath/System.String"
          }
        ],
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          }
        ]
      },
      {
        "id": "AllergyIntolerance.code.coding:atc.extension",
        "extension": [
          {
            "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status",
            "valueCode": "normative"
          },
          {
            "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-normative-version",
            "valueCode": "4.0.0"
          }
        ],
        "path": "AllergyIntolerance.code.coding.extension",
        "slicing": {
          "discriminator": [
            {
              "type": "value",
              "path": "url"
            }
          ],
          "description": "Extensions are always sliced by (at least) url",
          "rules": "open"
        },
        "short": "Additional content defined by implementations",
        "definition": "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance  applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.",
        "comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
        "alias": [
          "extensions",
          "user content"
        ],
        "min": 0,
        "max": "*",
        "base": {
          "path": "Element.extension",
          "min": 0,
          "max": "*"
        },
        "type": [
          {
            "code": "Extension"
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          },
          {
            "key": "ext-1",
            "severity": "error",
            "human": "Must have either extensions or value[x], not both",
            "expression": "extension.exists() != value.exists()",
            "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), 'value')])",
            "source": "http://hl7.org/fhir/StructureDefinition/Extension"
          }
        ],
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "rim",
            "map": "N/A"
          }
        ]
      },
      {
        "id": "AllergyIntolerance.code.coding:atc.system",
        "path": "AllergyIntolerance.code.coding.system",
        "short": "Identità del sistema terminologico",
        "definition": "L'identificazione del sistema di codice che definisce il significato del simbolo nel codice.",
        "comment": "L'URI può essere un OID (urn:oid:...) o un UUID (urn:uuid:...).  Gli OID e gli UUID DEVONO essere riferimenti al registro OID di HL7. Altrimenti, l'URI deve provenire dall'elenco di URI speciali definiti da HL7 per FHIR o deve fare riferimento a qualche definizione che stabilisca il sistema in modo chiaro e non ambiguo.",
        "requirements": "Need to be unambiguous about the source of the definition of the symbol.",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Coding.system",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "uri"
          }
        ],
        "fixedUri": "urn:uri:https://www.whocc.no/atc",
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          }
        ],
        "isSummary": true,
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "v2",
            "map": "C*E.3"
          },
          {
            "identity": "rim",
            "map": "./codeSystem"
          },
          {
            "identity": "orim",
            "map": "fhir:Coding.system rdfs:subPropertyOf dt:CDCoding.codeSystem"
          }
        ]
      },
      {
        "id": "AllergyIntolerance.code.coding:atc.version",
        "path": "AllergyIntolerance.code.coding.version",
        "short": "Version of the system - if relevant",
        "definition": "The version of the code system which was used when choosing this code. Note that a well-maintained code system does not need the version reported, because the meaning of codes is consistent across versions. However this cannot consistently be assured, and when the meaning is not guaranteed to be consistent, the version SHOULD be exchanged.",
        "comment": "Where the terminology does not clearly define what string should be used to identify code system versions, the recommendation is to use the date (expressed in FHIR date format) on which that version was officially published as the version date.",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Coding.version",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "string"
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          }
        ],
        "isSummary": true,
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "v2",
            "map": "C*E.7"
          },
          {
            "identity": "rim",
            "map": "./codeSystemVersion"
          },
          {
            "identity": "orim",
            "map": "fhir:Coding.version rdfs:subPropertyOf dt:CDCoding.codeSystemVersion"
          }
        ]
      },
      {
        "id": "AllergyIntolerance.code.coding:atc.code",
        "path": "AllergyIntolerance.code.coding.code",
        "short": "Symbol in syntax defined by the system",
        "definition": "A symbol in syntax defined by the system. The symbol may be a predefined code or an expression in a syntax defined by the coding system (e.g. post-coordination).",
        "comment": "Note that FHIR strings SHALL NOT exceed 1MB in size",
        "requirements": "Need to refer to a particular code in the system.",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Coding.code",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "code"
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          }
        ],
        "isSummary": true,
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "v2",
            "map": "C*E.1"
          },
          {
            "identity": "rim",
            "map": "./code"
          },
          {
            "identity": "orim",
            "map": "fhir:Coding.code rdfs:subPropertyOf dt:CDCoding.code"
          }
        ]
      },
      {
        "id": "AllergyIntolerance.code.coding:atc.display",
        "extension": [
          {
            "url": "http://hl7.org/fhir/StructureDefinition/elementdefinition-translatable",
            "valueBoolean": true
          }
        ],
        "path": "AllergyIntolerance.code.coding.display",
        "short": "Representation defined by the system",
        "definition": "A representation of the meaning of the code in the system, following the rules of the system.",
        "comment": "Note that FHIR strings SHALL NOT exceed 1MB in size",
        "requirements": "Need to be able to carry a human-readable meaning of the code for readers that do not know  the system.",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Coding.display",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "string"
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          }
        ],
        "isSummary": true,
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "v2",
            "map": "C*E.2 - but note this is not well followed"
          },
          {
            "identity": "rim",
            "map": "CV.displayName"
          },
          {
            "identity": "orim",
            "map": "fhir:Coding.display rdfs:subPropertyOf dt:CDCoding.displayName"
          }
        ]
      },
      {
        "id": "AllergyIntolerance.code.coding:atc.userSelected",
        "path": "AllergyIntolerance.code.coding.userSelected",
        "short": "If this coding was chosen directly by the user",
        "definition": "Indicates that this coding was chosen by a user directly - e.g. off a pick list of available items (codes or displays).",
        "comment": "Amongst a set of alternatives, a directly chosen code is the most appropriate starting point for new translations. There is some ambiguity about what exactly 'directly chosen' implies, and trading partner agreement may be needed to clarify the use of this element and its consequences more completely.",
        "requirements": "This has been identified as a clinical safety criterium - that this exact system/code pair was chosen explicitly, rather than inferred by the system based on some rules or language processing.",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Coding.userSelected",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "boolean"
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          }
        ],
        "isSummary": true,
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "v2",
            "map": "Sometimes implied by being first"
          },
          {
            "identity": "rim",
            "map": "CD.codingRationale"
          },
          {
            "identity": "orim",
            "map": "fhir:Coding.userSelected fhir:mapsTo dt:CDCoding.codingRationale. fhir:Coding.userSelected fhir:hasMap fhir:Coding.userSelected.map. fhir:Coding.userSelected.map a fhir:Map;   fhir:target dt:CDCoding.codingRationale. fhir:Coding.userSelected\\#true a [     fhir:source \"true\";     fhir:target dt:CDCoding.codingRationale\\#O   ]"
          }
        ]
      },
      {
        "id": "AllergyIntolerance.code.coding:absent-unknown-uv-ips",
        "extension": [
          {
            "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status",
            "valueCode": "normative"
          },
          {
            "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-normative-version",
            "valueCode": "4.0.0"
          }
        ],
        "path": "AllergyIntolerance.code.coding",
        "sliceName": "absent-unknown-uv-ips",
        "short": "Codice definito da un sistema terminologico",
        "definition": "Un riferimento a un codice definito da un sistema terminologico.",
        "comment": "I codici possono essere definiti in modo molto casuale in enumerazioni o elenchi di codici, fino a definizioni molto formali come SNOMED CT - si vedano i Core Principles di HL7 v3 per maggiori informazioni.  L'ordine dei codici non è definito e NON DEVE essere usato per dedurre il significato. In generale, al massimo uno solo dei valori di codifica sarà etichettato come UserSelected = true.",
        "requirements": "Allows for alternative encodings within a code system, and translations to other code systems.",
        "min": 0,
        "max": "*",
        "base": {
          "path": "CodeableConcept.coding",
          "min": 0,
          "max": "*"
        },
        "type": [
          {
            "code": "Coding"
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          }
        ],
        "isSummary": true,
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "v2",
            "map": "CE/CNE/CWE subset one of the sets of component 1-3 or 4-6"
          },
          {
            "identity": "rim",
            "map": "CV"
          },
          {
            "identity": "orim",
            "map": "fhir:Coding rdfs:subClassOf dt:CDCoding"
          },
          {
            "identity": "v2",
            "map": "C*E.1-8, C*E.10-22"
          },
          {
            "identity": "rim",
            "map": "union(., ./translation)"
          },
          {
            "identity": "orim",
            "map": "fhir:CodeableConcept.coding rdfs:subPropertyOf dt:CD.coding"
          }
        ]
      },
      {
        "id": "AllergyIntolerance.code.coding:absent-unknown-uv-ips.id",
        "path": "AllergyIntolerance.code.coding.id",
        "representation": [
          "xmlAttr"
        ],
        "short": "Unique id for inter-element referencing",
        "definition": "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Element.id",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
                "valueUrl": "string"
              }
            ],
            "code": "http://hl7.org/fhirpath/System.String"
          }
        ],
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          }
        ]
      },
      {
        "id": "AllergyIntolerance.code.coding:absent-unknown-uv-ips.extension",
        "extension": [
          {
            "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status",
            "valueCode": "normative"
          },
          {
            "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-normative-version",
            "valueCode": "4.0.0"
          }
        ],
        "path": "AllergyIntolerance.code.coding.extension",
        "slicing": {
          "discriminator": [
            {
              "type": "value",
              "path": "url"
            }
          ],
          "description": "Extensions are always sliced by (at least) url",
          "rules": "open"
        },
        "short": "Additional content defined by implementations",
        "definition": "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance  applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.",
        "comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
        "alias": [
          "extensions",
          "user content"
        ],
        "min": 0,
        "max": "*",
        "base": {
          "path": "Element.extension",
          "min": 0,
          "max": "*"
        },
        "type": [
          {
            "code": "Extension"
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          },
          {
            "key": "ext-1",
            "severity": "error",
            "human": "Must have either extensions or value[x], not both",
            "expression": "extension.exists() != value.exists()",
            "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), 'value')])",
            "source": "http://hl7.org/fhir/StructureDefinition/Extension"
          }
        ],
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "rim",
            "map": "N/A"
          }
        ]
      },
      {
        "id": "AllergyIntolerance.code.coding:absent-unknown-uv-ips.system",
        "path": "AllergyIntolerance.code.coding.system",
        "short": "Identità del sistema terminologico",
        "definition": "L'identificazione del sistema di codice che definisce il significato del simbolo nel codice.",
        "comment": "L'URI può essere un OID (urn:oid:...) o un UUID (urn:uuid:...).  Gli OID e gli UUID DEVONO essere riferimenti al registro OID di HL7. Altrimenti, l'URI deve provenire dall'elenco di URI speciali definiti da HL7 per FHIR o deve fare riferimento a qualche definizione che stabilisca il sistema in modo chiaro e non ambiguo.",
        "requirements": "Need to be unambiguous about the source of the definition of the symbol.",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Coding.system",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "uri"
          }
        ],
        "fixedUri": "http://hl7.org/fhir/uv/ips/CodeSystem/absent-unknown-uv-ips",
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          }
        ],
        "isSummary": true,
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "v2",
            "map": "C*E.3"
          },
          {
            "identity": "rim",
            "map": "./codeSystem"
          },
          {
            "identity": "orim",
            "map": "fhir:Coding.system rdfs:subPropertyOf dt:CDCoding.codeSystem"
          }
        ]
      },
      {
        "id": "AllergyIntolerance.code.coding:absent-unknown-uv-ips.version",
        "path": "AllergyIntolerance.code.coding.version",
        "short": "Version of the system - if relevant",
        "definition": "The version of the code system which was used when choosing this code. Note that a well-maintained code system does not need the version reported, because the meaning of codes is consistent across versions. However this cannot consistently be assured, and when the meaning is not guaranteed to be consistent, the version SHOULD be exchanged.",
        "comment": "Where the terminology does not clearly define what string should be used to identify code system versions, the recommendation is to use the date (expressed in FHIR date format) on which that version was officially published as the version date.",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Coding.version",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "string"
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          }
        ],
        "isSummary": true,
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "v2",
            "map": "C*E.7"
          },
          {
            "identity": "rim",
            "map": "./codeSystemVersion"
          },
          {
            "identity": "orim",
            "map": "fhir:Coding.version rdfs:subPropertyOf dt:CDCoding.codeSystemVersion"
          }
        ]
      },
      {
        "id": "AllergyIntolerance.code.coding:absent-unknown-uv-ips.code",
        "path": "AllergyIntolerance.code.coding.code",
        "short": "Symbol in syntax defined by the system",
        "definition": "A symbol in syntax defined by the system. The symbol may be a predefined code or an expression in a syntax defined by the coding system (e.g. post-coordination).",
        "comment": "Note that FHIR strings SHALL NOT exceed 1MB in size",
        "requirements": "Need to refer to a particular code in the system.",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Coding.code",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "code"
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          }
        ],
        "isSummary": true,
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "v2",
            "map": "C*E.1"
          },
          {
            "identity": "rim",
            "map": "./code"
          },
          {
            "identity": "orim",
            "map": "fhir:Coding.code rdfs:subPropertyOf dt:CDCoding.code"
          }
        ]
      },
      {
        "id": "AllergyIntolerance.code.coding:absent-unknown-uv-ips.display",
        "extension": [
          {
            "url": "http://hl7.org/fhir/StructureDefinition/elementdefinition-translatable",
            "valueBoolean": true
          }
        ],
        "path": "AllergyIntolerance.code.coding.display",
        "short": "Representation defined by the system",
        "definition": "A representation of the meaning of the code in the system, following the rules of the system.",
        "comment": "Note that FHIR strings SHALL NOT exceed 1MB in size",
        "requirements": "Need to be able to carry a human-readable meaning of the code for readers that do not know  the system.",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Coding.display",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "string"
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          }
        ],
        "isSummary": true,
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "v2",
            "map": "C*E.2 - but note this is not well followed"
          },
          {
            "identity": "rim",
            "map": "CV.displayName"
          },
          {
            "identity": "orim",
            "map": "fhir:Coding.display rdfs:subPropertyOf dt:CDCoding.displayName"
          }
        ]
      },
      {
        "id": "AllergyIntolerance.code.coding:absent-unknown-uv-ips.userSelected",
        "path": "AllergyIntolerance.code.coding.userSelected",
        "short": "If this coding was chosen directly by the user",
        "definition": "Indicates that this coding was chosen by a user directly - e.g. off a pick list of available items (codes or displays).",
        "comment": "Amongst a set of alternatives, a directly chosen code is the most appropriate starting point for new translations. There is some ambiguity about what exactly 'directly chosen' implies, and trading partner agreement may be needed to clarify the use of this element and its consequences more completely.",
        "requirements": "This has been identified as a clinical safety criterium - that this exact system/code pair was chosen explicitly, rather than inferred by the system based on some rules or language processing.",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Coding.userSelected",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "boolean"
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          }
        ],
        "isSummary": true,
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "v2",
            "map": "Sometimes implied by being first"
          },
          {
            "identity": "rim",
            "map": "CD.codingRationale"
          },
          {
            "identity": "orim",
            "map": "fhir:Coding.userSelected fhir:mapsTo dt:CDCoding.codingRationale. fhir:Coding.userSelected fhir:hasMap fhir:Coding.userSelected.map. fhir:Coding.userSelected.map a fhir:Map;   fhir:target dt:CDCoding.codingRationale. fhir:Coding.userSelected\\#true a [     fhir:source \"true\";     fhir:target dt:CDCoding.codingRationale\\#O   ]"
          }
        ]
      },
      {
        "id": "AllergyIntolerance.code.text",
        "extension": [
          {
            "url": "http://hl7.org/fhir/StructureDefinition/elementdefinition-translatable",
            "valueBoolean": true
          }
        ],
        "path": "AllergyIntolerance.code.text",
        "short": "Plain text representation of the concept",
        "definition": "A human language representation of the concept as seen/selected/uttered by the user who entered the data and/or which represents the intended meaning of the user.",
        "comment": "Very often the text is the same as a displayName of one of the codings.",
        "requirements": "The codes from the terminologies do not always capture the correct meaning with all the nuances of the human using them, or sometimes there is no appropriate code at all. In these cases, the text is used to capture the full meaning of the source.",
        "min": 0,
        "max": "1",
        "base": {
          "path": "CodeableConcept.text",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "string"
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          }
        ],
        "isSummary": true,
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "v2",
            "map": "C*E.9. But note many systems use C*E.2 for this"
          },
          {
            "identity": "rim",
            "map": "./originalText[mediaType/code=\"text/plain\"]/data"
          },
          {
            "identity": "orim",
            "map": "fhir:CodeableConcept.text rdfs:subPropertyOf dt:CD.originalText"
          }
        ]
      },
      {
        "id": "AllergyIntolerance.patient",
        "extension": [
          {
            "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status",
            "valueCode": "normative"
          },
          {
            "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-normative-version",
            "valueCode": "4.0.0"
          }
        ],
        "path": "AllergyIntolerance.patient",
        "short": "A chi è rivolta la sensibilità",
        "definition": "Il paziente affetto da allergia o intolleranza.",
        "comment": "I riferimenti DEVONO essere un riferimento a una risorsa FHIR effettiva e DEVONO essere risolvibili (consentendo il controllo dell'accesso, la non disponibilità temporanea, ecc.) La risoluzione può avvenire tramite recupero dall'URL o, se applicabile per tipo di risorsa, trattando un riferimento assoluto come un URL canonico e cercandolo in un registro/repository locale.",
        "alias": [
          "Patient"
        ],
        "min": 1,
        "max": "1",
        "base": {
          "path": "AllergyIntolerance.patient",
          "min": 1,
          "max": "1"
        },
        "type": [
          {
            "code": "Reference",
            "targetProfile": [
              "https://eng.it/fhir/StructureDefinition/Patient_Eng"
            ]
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          },
          {
            "key": "ref-1",
            "severity": "error",
            "human": "SHALL have a contained resource if a local reference is provided",
            "expression": "reference.startsWith('#').not() or (reference.substring(1).trace('url') in %rootResource.contained.id.trace('ids'))",
            "xpath": "not(starts-with(f:reference/@value, '#')) or exists(ancestor::*[self::f:entry or self::f:parameter]/f:resource/f:*/f:contained/f:*[f:id/@value=substring-after(current()/f:reference/@value, '#')]|/*/f:contained/f:*[f:id/@value=substring-after(current()/f:reference/@value, '#')])",
            "source": "http://hl7.org/fhir/StructureDefinition/Reference"
          }
        ],
        "isSummary": true,
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "rim",
            "map": "The target of a resource reference is a RIM entry point (Act, Role, or Entity)"
          },
          {
            "identity": "w5",
            "map": "FiveWs.subject[x]"
          },
          {
            "identity": "v2",
            "map": "(PID-3)"
          },
          {
            "identity": "rim",
            "map": ".participation[typeCode=SBJ].role[classCode=PAT]"
          },
          {
            "identity": "w5",
            "map": "FiveWs.subject"
          }
        ]
      },
      {
        "id": "AllergyIntolerance.encounter",
        "extension": [
          {
            "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status",
            "valueCode": "normative"
          },
          {
            "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-normative-version",
            "valueCode": "4.0.0"
          }
        ],
        "path": "AllergyIntolerance.encounter",
        "short": "Encounter when the allergy or intolerance was asserted",
        "definition": "The encounter when the allergy or intolerance was asserted.",
        "comment": "References SHALL be a reference to an actual FHIR resource, and SHALL be resolveable (allowing for access control, temporary unavailability, etc.). Resolution can be either by retrieval from the URL, or, where applicable by resource type, by treating an absolute reference as a canonical URL and looking it up in a local registry/repository.",
        "min": 0,
        "max": "1",
        "base": {
          "path": "AllergyIntolerance.encounter",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "Reference",
            "targetProfile": [
              "https://eng.it/fhir/StructureDefinition/Encounter_ADT_Eng",
              "https://eng.it/fhir/StructureDefinition/Encounter_AMB_Eng",
              "https://eng.it/fhir/StructureDefinition/Encounter_WL_Eng",
              "https://eng.it/fhir/StructureDefinition/Encounter_ER_Eng"
            ]
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          },
          {
            "key": "ref-1",
            "severity": "error",
            "human": "SHALL have a contained resource if a local reference is provided",
            "expression": "reference.startsWith('#').not() or (reference.substring(1).trace('url') in %rootResource.contained.id.trace('ids'))",
            "xpath": "not(starts-with(f:reference/@value, '#')) or exists(ancestor::*[self::f:entry or self::f:parameter]/f:resource/f:*/f:contained/f:*[f:id/@value=substring-after(current()/f:reference/@value, '#')]|/*/f:contained/f:*[f:id/@value=substring-after(current()/f:reference/@value, '#')])",
            "source": "http://hl7.org/fhir/StructureDefinition/Reference"
          }
        ],
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "rim",
            "map": "The target of a resource reference is a RIM entry point (Act, Role, or Entity)"
          },
          {
            "identity": "w5",
            "map": "FiveWs.context"
          },
          {
            "identity": "rim",
            "map": ".inboundRelationship[typeCode=COMP].source[classCode=ENC, moodCode=EVN]"
          }
        ]
      },
      {
        "id": "AllergyIntolerance.onset[x]",
        "path": "AllergyIntolerance.onset[x]",
        "short": "Quando è stata identificata un'allergia o un'intolleranza",
        "definition": "Data, ora o età stimata o effettiva in cui è stata identificata l'allergia o l'intolleranza.",
        "min": 0,
        "max": "1",
        "base": {
          "path": "AllergyIntolerance.onset[x]",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "dateTime"
          },
          {
            "code": "Period"
          },
          {
            "code": "string"
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          }
        ],
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "w5",
            "map": "FiveWs.init"
          },
          {
            "identity": "rim",
            "map": "effectiveTime.low"
          }
        ]
      },
      {
        "id": "AllergyIntolerance.recordedDate",
        "path": "AllergyIntolerance.recordedDate",
        "short": "Date first version of the resource instance was recorded",
        "definition": "The recordedDate represents when this particular AllergyIntolerance record was created in the system, which is often a system-generated date.",
        "min": 0,
        "max": "1",
        "base": {
          "path": "AllergyIntolerance.recordedDate",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "dateTime"
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          }
        ],
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "w5",
            "map": "FiveWs.recorded"
          },
          {
            "identity": "v2",
            "map": "IAM-13"
          },
          {
            "identity": "rim",
            "map": ".participation[typeCode=AUT].time"
          }
        ]
      },
      {
        "id": "AllergyIntolerance.recorder",
        "extension": [
          {
            "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status",
            "valueCode": "normative"
          },
          {
            "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-normative-version",
            "valueCode": "4.0.0"
          }
        ],
        "path": "AllergyIntolerance.recorder",
        "short": "Chi ha registrato la sensibilità",
        "definition": "Persona che ha registrato la registrazione e si assume la responsabilità del suo contenuto.",
        "comment": "I riferimenti DEVONO essere un riferimento a una risorsa FHIR effettiva e DEVONO essere risolvibili (consentendo il controllo dell'accesso, la non disponibilità temporanea, ecc.) La risoluzione può avvenire tramite recupero dall'URL o, se applicabile per tipo di risorsa, trattando un riferimento assoluto come un URL canonico e cercandolo in un registro/repository locale.",
        "alias": [
          "Author"
        ],
        "min": 0,
        "max": "1",
        "base": {
          "path": "AllergyIntolerance.recorder",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "Reference",
            "targetProfile": [
              "https://eng.it/fhir/StructureDefinition/Practitioner_Eng"
            ]
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          },
          {
            "key": "ref-1",
            "severity": "error",
            "human": "SHALL have a contained resource if a local reference is provided",
            "expression": "reference.startsWith('#').not() or (reference.substring(1).trace('url') in %rootResource.contained.id.trace('ids'))",
            "xpath": "not(starts-with(f:reference/@value, '#')) or exists(ancestor::*[self::f:entry or self::f:parameter]/f:resource/f:*/f:contained/f:*[f:id/@value=substring-after(current()/f:reference/@value, '#')]|/*/f:contained/f:*[f:id/@value=substring-after(current()/f:reference/@value, '#')])",
            "source": "http://hl7.org/fhir/StructureDefinition/Reference"
          }
        ],
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "rim",
            "map": "The target of a resource reference is a RIM entry point (Act, Role, or Entity)"
          },
          {
            "identity": "w5",
            "map": "FiveWs.author"
          },
          {
            "identity": "rim",
            "map": ".participation[typeCode=AUT].role"
          }
        ]
      },
      {
        "id": "AllergyIntolerance.asserter",
        "extension": [
          {
            "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status",
            "valueCode": "normative"
          },
          {
            "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-normative-version",
            "valueCode": "4.0.0"
          }
        ],
        "path": "AllergyIntolerance.asserter",
        "short": "Source of the information about the allergy",
        "definition": "The source of the information about the allergy that is recorded.",
        "comment": "The recorder takes responsibility for the content, but can reference the source from where they got it.",
        "alias": [
          "Source",
          "Informant"
        ],
        "min": 0,
        "max": "1",
        "base": {
          "path": "AllergyIntolerance.asserter",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "Reference",
            "targetProfile": [
              "http://hl7.org/fhir/StructureDefinition/Patient",
              "http://hl7.org/fhir/StructureDefinition/RelatedPerson",
              "http://hl7.org/fhir/StructureDefinition/Practitioner",
              "http://hl7.org/fhir/StructureDefinition/PractitionerRole"
            ]
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          },
          {
            "key": "ref-1",
            "severity": "error",
            "human": "SHALL have a contained resource if a local reference is provided",
            "expression": "reference.startsWith('#').not() or (reference.substring(1).trace('url') in %rootResource.contained.id.trace('ids'))",
            "xpath": "not(starts-with(f:reference/@value, '#')) or exists(ancestor::*[self::f:entry or self::f:parameter]/f:resource/f:*/f:contained/f:*[f:id/@value=substring-after(current()/f:reference/@value, '#')]|/*/f:contained/f:*[f:id/@value=substring-after(current()/f:reference/@value, '#')])",
            "source": "http://hl7.org/fhir/StructureDefinition/Reference"
          }
        ],
        "isSummary": true,
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "rim",
            "map": "The target of a resource reference is a RIM entry point (Act, Role, or Entity)"
          },
          {
            "identity": "w5",
            "map": "FiveWs.source"
          },
          {
            "identity": "v2",
            "map": "IAM-14 (if patient) / IAM-18 (if practitioner)"
          },
          {
            "identity": "rim",
            "map": ".participation[typeCode=INF].role"
          }
        ]
      },
      {
        "id": "AllergyIntolerance.lastOccurrence",
        "path": "AllergyIntolerance.lastOccurrence",
        "short": "Date(/time) of last known occurrence of a reaction",
        "definition": "Represents the date and/or time of the last known occurrence of a reaction event.",
        "comment": "This date may be replicated by one of the Onset of Reaction dates. Where a textual representation of the date of last occurrence is required e.g. 'In Childhood, '10 years ago' the Comment element should be used.",
        "min": 0,
        "max": "1",
        "base": {
          "path": "AllergyIntolerance.lastOccurrence",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "dateTime"
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          }
        ],
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "rim",
            "map": "outBoundRelationship[typeCode=SUBJ].target[classCode=OBS, moodCode=EVN, code <= CommonClinicalObservationType, value <= ObservationValue (Reaction Type)].effectiveTime"
          }
        ]
      },
      {
        "id": "AllergyIntolerance.note",
        "extension": [
          {
            "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status",
            "valueCode": "normative"
          },
          {
            "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-normative-version",
            "valueCode": "4.0.0"
          }
        ],
        "path": "AllergyIntolerance.note",
        "short": "Additional text not captured in other fields",
        "definition": "Additional narrative about the propensity for the Adverse Reaction, not captured in other fields.",
        "comment": "For example: including reason for flagging a seriousness of 'High Risk'; and instructions related to future exposure or administration of the substance, such as administration within an Intensive Care Unit or under corticosteroid cover. The notes should be related to an allergy or intolerance as a condition in general and not related to any particular episode of it. For episode notes and descriptions, use AllergyIntolerance.event.description and  AllergyIntolerance.event.notes.",
        "min": 0,
        "max": "*",
        "base": {
          "path": "AllergyIntolerance.note",
          "min": 0,
          "max": "*"
        },
        "type": [
          {
            "code": "Annotation"
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          }
        ],
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "v2",
            "map": "N/A"
          },
          {
            "identity": "rim",
            "map": "Act"
          },
          {
            "identity": "rim",
            "map": "subjectOf.observationEvent[code=\"annotation\"].value"
          }
        ]
      },
      {
        "id": "AllergyIntolerance.reaction",
        "extension": [
          {
            "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status",
            "valueCode": "normative"
          },
          {
            "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-normative-version",
            "valueCode": "4.0.0"
          }
        ],
        "path": "AllergyIntolerance.reaction",
        "short": "Reazione avversa Eventi legati all'esposizione alla sostanza",
        "definition": "Dettagli su ciascun evento avverso legato all'esposizione alla sostanza identificata.",
        "min": 0,
        "max": "*",
        "base": {
          "path": "AllergyIntolerance.reaction",
          "min": 0,
          "max": "*"
        },
        "type": [
          {
            "code": "BackboneElement"
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          }
        ],
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "rim",
            "map": "outBoundRelationship[typeCode=SUBJ].target[classCode=OBS, moodCode=EVN, code <= CommonClinicalObservationType, value <= ObservationValue (Reaction Type)]"
          }
        ]
      },
      {
        "id": "AllergyIntolerance.reaction.id",
        "path": "AllergyIntolerance.reaction.id",
        "representation": [
          "xmlAttr"
        ],
        "short": "Unique id for inter-element referencing",
        "definition": "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Element.id",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
                "valueUrl": "string"
              }
            ],
            "code": "http://hl7.org/fhirpath/System.String"
          }
        ],
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          }
        ]
      },
      {
        "id": "AllergyIntolerance.reaction.extension",
        "extension": [
          {
            "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status",
            "valueCode": "normative"
          },
          {
            "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-normative-version",
            "valueCode": "4.0.0"
          }
        ],
        "path": "AllergyIntolerance.reaction.extension",
        "slicing": {
          "discriminator": [
            {
              "type": "value",
              "path": "url"
            }
          ],
          "description": "Extensions are always sliced by (at least) url",
          "rules": "open"
        },
        "short": "Additional content defined by implementations",
        "definition": "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance  applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.",
        "comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
        "alias": [
          "extensions",
          "user content"
        ],
        "min": 0,
        "max": "*",
        "base": {
          "path": "Element.extension",
          "min": 0,
          "max": "*"
        },
        "type": [
          {
            "code": "Extension"
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          },
          {
            "key": "ext-1",
            "severity": "error",
            "human": "Must have either extensions or value[x], not both",
            "expression": "extension.exists() != value.exists()",
            "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), 'value')])",
            "source": "http://hl7.org/fhir/StructureDefinition/Extension"
          }
        ],
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "rim",
            "map": "N/A"
          }
        ]
      },
      {
        "id": "AllergyIntolerance.reaction.modifierExtension",
        "extension": [
          {
            "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status",
            "valueCode": "normative"
          },
          {
            "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-normative-version",
            "valueCode": "4.0.0"
          }
        ],
        "path": "AllergyIntolerance.reaction.modifierExtension",
        "short": "Extensions that cannot be ignored even if unrecognized",
        "definition": "May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.\n\nModifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).",
        "comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
        "requirements": "Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored.  This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](extensibility.html#modifierExtension).",
        "alias": [
          "extensions",
          "user content",
          "modifiers"
        ],
        "min": 0,
        "max": "*",
        "base": {
          "path": "BackboneElement.modifierExtension",
          "min": 0,
          "max": "*"
        },
        "type": [
          {
            "code": "Extension"
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          },
          {
            "key": "ext-1",
            "severity": "error",
            "human": "Must have either extensions or value[x], not both",
            "expression": "extension.exists() != value.exists()",
            "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), 'value')])",
            "source": "http://hl7.org/fhir/StructureDefinition/Extension"
          }
        ],
        "isModifier": true,
        "isModifierReason": "Modifier extensions are expected to modify the meaning or interpretation of the element that contains them",
        "isSummary": true,
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "rim",
            "map": "N/A"
          }
        ]
      },
      {
        "id": "AllergyIntolerance.reaction.substance",
        "extension": [
          {
            "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status",
            "valueCode": "normative"
          },
          {
            "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-normative-version",
            "valueCode": "4.0.0"
          }
        ],
        "path": "AllergyIntolerance.reaction.substance",
        "short": "Specific substance or pharmaceutical product considered to be responsible for event",
        "definition": "Identification of the specific substance (or pharmaceutical product) considered to be responsible for the Adverse Reaction event. Note: the substance for a specific reaction may be different from the substance identified as the cause of the risk, but it must be consistent with it. For instance, it may be a more specific substance (e.g. a brand medication) or a composite product that includes the identified substance. It must be clinically safe to only process the 'code' and ignore the 'reaction.substance'.  If a receiving system is unable to confirm that AllergyIntolerance.reaction.substance falls within the semantic scope of AllergyIntolerance.code, then the receiving system should ignore AllergyIntolerance.reaction.substance.",
        "comment": "Coding of the specific substance (or pharmaceutical product) with a terminology capable of triggering decision support should be used wherever possible.  The 'code' element allows for the use of a specific substance or pharmaceutical product, or a group or class of substances. In the case of an allergy or intolerance to a class of substances, (for example, \"penicillins\"), the 'reaction.substance' element could be used to code the specific substance that was identified as having caused the reaction (for example, \"amoxycillin\"). Duplication of the value in the 'code' and 'reaction.substance' elements is acceptable when a specific substance has been recorded in 'code'.",
        "min": 0,
        "max": "1",
        "base": {
          "path": "AllergyIntolerance.reaction.substance",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "CodeableConcept"
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          }
        ],
        "binding": {
          "extension": [
            {
              "url": "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName",
              "valueString": "SubstanceCode"
            }
          ],
          "strength": "example",
          "description": "Codes defining the type of the substance (including pharmaceutical products).",
          "valueSet": "http://hl7.org/fhir/ValueSet/substance-code"
        },
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "v2",
            "map": "CE/CNE/CWE"
          },
          {
            "identity": "rim",
            "map": "CD"
          },
          {
            "identity": "orim",
            "map": "fhir:CodeableConcept rdfs:subClassOf dt:CD"
          },
          {
            "identity": "rim",
            "map": "outBoundRelationship[typeCode=SAS].target[classCode=SBADM, code <= ExposureCode].participation[typeCode=CSM].role[classCode=ADMM].player[classCode=MAT, determinerCode=KIND, code <= ExposureAgentEntityType]"
          }
        ]
      },
      {
        "id": "AllergyIntolerance.reaction.manifestation",
        "extension": [
          {
            "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status",
            "valueCode": "normative"
          },
          {
            "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-normative-version",
            "valueCode": "4.0.0"
          }
        ],
        "path": "AllergyIntolerance.reaction.manifestation",
        "slicing": {
          "discriminator": [
            {
              "type": "value",
              "path": "coding.system"
            }
          ],
          "rules": "open"
        },
        "short": "Sintomi/segni clinici associati all'evento",
        "definition": "Sintomi e/o segni clinici osservati o associati all'evento avverso.",
        "comment": "La manifestazione può essere espressa come una singola parola, una frase o una breve descrizione. Ad esempio: nausea, eruzione cutanea o nessuna reazione. È preferibile che la manifestazione sia codificata con una terminologia, ove possibile. I valori qui inseriti possono essere utilizzati per essere visualizzati su una schermata dell'applicazione come parte di un elenco di reazioni avverse, come raccomandato nelle linee guida CUI del NHS britannico.  Le terminologie comunemente utilizzate includono, ma non solo, SNOMED CT o ICD10.",
        "alias": [
          "Symptoms",
          "Signs"
        ],
        "min": 1,
        "max": "*",
        "base": {
          "path": "AllergyIntolerance.reaction.manifestation",
          "min": 1,
          "max": "*"
        },
        "type": [
          {
            "code": "CodeableConcept"
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          }
        ],
        "binding": {
          "extension": [
            {
              "url": "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName",
              "valueString": "Manifestation"
            }
          ],
          "strength": "example",
          "description": "Clinical symptoms and/or signs that are observed or associated with an Adverse Reaction Event.",
          "valueSet": "http://hl7.org/fhir/ValueSet/clinical-findings"
        },
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "v2",
            "map": "CE/CNE/CWE"
          },
          {
            "identity": "rim",
            "map": "CD"
          },
          {
            "identity": "orim",
            "map": "fhir:CodeableConcept rdfs:subClassOf dt:CD"
          },
          {
            "identity": "v2",
            "map": "AL1-5"
          },
          {
            "identity": "rim",
            "map": "code"
          }
        ]
      },
      {
        "id": "AllergyIntolerance.reaction.manifestation:clinical-findings",
        "extension": [
          {
            "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status",
            "valueCode": "normative"
          },
          {
            "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-normative-version",
            "valueCode": "4.0.0"
          }
        ],
        "path": "AllergyIntolerance.reaction.manifestation",
        "sliceName": "clinical-findings",
        "short": "Sintomi/segni clinici associati all'evento",
        "definition": "Sintomi e/o segni clinici osservati o associati all'evento avverso.",
        "comment": "La manifestazione può essere espressa come una singola parola, una frase o una breve descrizione. Ad esempio: nausea, eruzione cutanea o nessuna reazione. È preferibile che la manifestazione sia codificata con una terminologia, ove possibile. I valori qui inseriti possono essere utilizzati per essere visualizzati su una schermata dell'applicazione come parte di un elenco di reazioni avverse, come raccomandato nelle linee guida CUI del NHS britannico.  Le terminologie comunemente utilizzate includono, ma non solo, SNOMED CT o ICD10.",
        "alias": [
          "Symptoms",
          "Signs"
        ],
        "min": 0,
        "max": "*",
        "base": {
          "path": "AllergyIntolerance.reaction.manifestation",
          "min": 1,
          "max": "*"
        },
        "type": [
          {
            "code": "CodeableConcept"
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          }
        ],
        "binding": {
          "extension": [
            {
              "url": "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName",
              "valueString": "Manifestation"
            }
          ],
          "strength": "example",
          "description": "Clinical symptoms and/or signs that are observed or associated with an Adverse Reaction Event.",
          "valueSet": "http://hl7.org/fhir/ValueSet/clinical-findings"
        },
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "v2",
            "map": "CE/CNE/CWE"
          },
          {
            "identity": "rim",
            "map": "CD"
          },
          {
            "identity": "orim",
            "map": "fhir:CodeableConcept rdfs:subClassOf dt:CD"
          },
          {
            "identity": "v2",
            "map": "AL1-5"
          },
          {
            "identity": "rim",
            "map": "code"
          }
        ]
      },
      {
        "id": "AllergyIntolerance.reaction.manifestation:clinical-findings.id",
        "path": "AllergyIntolerance.reaction.manifestation.id",
        "representation": [
          "xmlAttr"
        ],
        "short": "Unique id for inter-element referencing",
        "definition": "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Element.id",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
                "valueUrl": "string"
              }
            ],
            "code": "http://hl7.org/fhirpath/System.String"
          }
        ],
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          }
        ]
      },
      {
        "id": "AllergyIntolerance.reaction.manifestation:clinical-findings.extension",
        "extension": [
          {
            "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status",
            "valueCode": "normative"
          },
          {
            "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-normative-version",
            "valueCode": "4.0.0"
          }
        ],
        "path": "AllergyIntolerance.reaction.manifestation.extension",
        "slicing": {
          "discriminator": [
            {
              "type": "value",
              "path": "url"
            }
          ],
          "description": "Extensions are always sliced by (at least) url",
          "rules": "open"
        },
        "short": "Additional content defined by implementations",
        "definition": "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance  applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.",
        "comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
        "alias": [
          "extensions",
          "user content"
        ],
        "min": 0,
        "max": "*",
        "base": {
          "path": "Element.extension",
          "min": 0,
          "max": "*"
        },
        "type": [
          {
            "code": "Extension"
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          },
          {
            "key": "ext-1",
            "severity": "error",
            "human": "Must have either extensions or value[x], not both",
            "expression": "extension.exists() != value.exists()",
            "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), 'value')])",
            "source": "http://hl7.org/fhir/StructureDefinition/Extension"
          }
        ],
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "rim",
            "map": "N/A"
          }
        ]
      },
      {
        "id": "AllergyIntolerance.reaction.manifestation:clinical-findings.coding",
        "extension": [
          {
            "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status",
            "valueCode": "normative"
          },
          {
            "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-normative-version",
            "valueCode": "4.0.0"
          }
        ],
        "path": "AllergyIntolerance.reaction.manifestation.coding",
        "short": "Codice definito da un sistema terminologico",
        "definition": "Un riferimento a un codice definito da un sistema terminologico.",
        "comment": "I codici possono essere definiti in modo molto casuale in enumerazioni o elenchi di codici, fino a definizioni molto formali come SNOMED CT - si vedano i Core Principles di HL7 v3 per maggiori informazioni.  L'ordine dei codici non è definito e NON DEVE essere usato per dedurre il significato. In generale, al massimo uno solo dei valori di codifica sarà etichettato come UserSelected = true.",
        "requirements": "Allows for alternative encodings within a code system, and translations to other code systems.",
        "min": 0,
        "max": "*",
        "base": {
          "path": "CodeableConcept.coding",
          "min": 0,
          "max": "*"
        },
        "type": [
          {
            "code": "Coding"
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          }
        ],
        "isSummary": true,
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "v2",
            "map": "CE/CNE/CWE subset one of the sets of component 1-3 or 4-6"
          },
          {
            "identity": "rim",
            "map": "CV"
          },
          {
            "identity": "orim",
            "map": "fhir:Coding rdfs:subClassOf dt:CDCoding"
          },
          {
            "identity": "v2",
            "map": "C*E.1-8, C*E.10-22"
          },
          {
            "identity": "rim",
            "map": "union(., ./translation)"
          },
          {
            "identity": "orim",
            "map": "fhir:CodeableConcept.coding rdfs:subPropertyOf dt:CD.coding"
          }
        ]
      },
      {
        "id": "AllergyIntolerance.reaction.manifestation:clinical-findings.coding.id",
        "path": "AllergyIntolerance.reaction.manifestation.coding.id",
        "representation": [
          "xmlAttr"
        ],
        "short": "Unique id for inter-element referencing",
        "definition": "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Element.id",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
                "valueUrl": "string"
              }
            ],
            "code": "http://hl7.org/fhirpath/System.String"
          }
        ],
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          }
        ]
      },
      {
        "id": "AllergyIntolerance.reaction.manifestation:clinical-findings.coding.extension",
        "extension": [
          {
            "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status",
            "valueCode": "normative"
          },
          {
            "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-normative-version",
            "valueCode": "4.0.0"
          }
        ],
        "path": "AllergyIntolerance.reaction.manifestation.coding.extension",
        "slicing": {
          "discriminator": [
            {
              "type": "value",
              "path": "url"
            }
          ],
          "description": "Extensions are always sliced by (at least) url",
          "rules": "open"
        },
        "short": "Additional content defined by implementations",
        "definition": "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance  applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.",
        "comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
        "alias": [
          "extensions",
          "user content"
        ],
        "min": 0,
        "max": "*",
        "base": {
          "path": "Element.extension",
          "min": 0,
          "max": "*"
        },
        "type": [
          {
            "code": "Extension"
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          },
          {
            "key": "ext-1",
            "severity": "error",
            "human": "Must have either extensions or value[x], not both",
            "expression": "extension.exists() != value.exists()",
            "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), 'value')])",
            "source": "http://hl7.org/fhir/StructureDefinition/Extension"
          }
        ],
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "rim",
            "map": "N/A"
          }
        ]
      },
      {
        "id": "AllergyIntolerance.reaction.manifestation:clinical-findings.coding.system",
        "path": "AllergyIntolerance.reaction.manifestation.coding.system",
        "short": "Identità del sistema terminologico",
        "definition": "L'identificazione del sistema di codice che definisce il significato del simbolo nel codice.",
        "comment": "L'URI può essere un OID (urn:oid:...) o un UUID (urn:uuid:...).  Gli OID e gli UUID DEVONO essere riferimenti al registro OID di HL7. Altrimenti, l'URI deve provenire dall'elenco di URI speciali definiti da HL7 per FHIR o deve fare riferimento a qualche definizione che stabilisca il sistema in modo chiaro e non ambiguo.",
        "requirements": "Need to be unambiguous about the source of the definition of the symbol.",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Coding.system",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "uri"
          }
        ],
        "fixedUri": "http://hl7.org/fhir/CodeSystem/clinical-findings",
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          }
        ],
        "isSummary": true,
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "v2",
            "map": "C*E.3"
          },
          {
            "identity": "rim",
            "map": "./codeSystem"
          },
          {
            "identity": "orim",
            "map": "fhir:Coding.system rdfs:subPropertyOf dt:CDCoding.codeSystem"
          }
        ]
      },
      {
        "id": "AllergyIntolerance.reaction.manifestation:clinical-findings.coding.version",
        "path": "AllergyIntolerance.reaction.manifestation.coding.version",
        "short": "Version of the system - if relevant",
        "definition": "The version of the code system which was used when choosing this code. Note that a well-maintained code system does not need the version reported, because the meaning of codes is consistent across versions. However this cannot consistently be assured, and when the meaning is not guaranteed to be consistent, the version SHOULD be exchanged.",
        "comment": "Where the terminology does not clearly define what string should be used to identify code system versions, the recommendation is to use the date (expressed in FHIR date format) on which that version was officially published as the version date.",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Coding.version",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "string"
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          }
        ],
        "isSummary": true,
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "v2",
            "map": "C*E.7"
          },
          {
            "identity": "rim",
            "map": "./codeSystemVersion"
          },
          {
            "identity": "orim",
            "map": "fhir:Coding.version rdfs:subPropertyOf dt:CDCoding.codeSystemVersion"
          }
        ]
      },
      {
        "id": "AllergyIntolerance.reaction.manifestation:clinical-findings.coding.code",
        "path": "AllergyIntolerance.reaction.manifestation.coding.code",
        "short": "Symbol in syntax defined by the system",
        "definition": "A symbol in syntax defined by the system. The symbol may be a predefined code or an expression in a syntax defined by the coding system (e.g. post-coordination).",
        "comment": "Note that FHIR strings SHALL NOT exceed 1MB in size",
        "requirements": "Need to refer to a particular code in the system.",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Coding.code",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "code"
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          }
        ],
        "isSummary": true,
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "v2",
            "map": "C*E.1"
          },
          {
            "identity": "rim",
            "map": "./code"
          },
          {
            "identity": "orim",
            "map": "fhir:Coding.code rdfs:subPropertyOf dt:CDCoding.code"
          }
        ]
      },
      {
        "id": "AllergyIntolerance.reaction.manifestation:clinical-findings.coding.display",
        "extension": [
          {
            "url": "http://hl7.org/fhir/StructureDefinition/elementdefinition-translatable",
            "valueBoolean": true
          }
        ],
        "path": "AllergyIntolerance.reaction.manifestation.coding.display",
        "short": "Representation defined by the system",
        "definition": "A representation of the meaning of the code in the system, following the rules of the system.",
        "comment": "Note that FHIR strings SHALL NOT exceed 1MB in size",
        "requirements": "Need to be able to carry a human-readable meaning of the code for readers that do not know  the system.",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Coding.display",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "string"
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          }
        ],
        "isSummary": true,
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "v2",
            "map": "C*E.2 - but note this is not well followed"
          },
          {
            "identity": "rim",
            "map": "CV.displayName"
          },
          {
            "identity": "orim",
            "map": "fhir:Coding.display rdfs:subPropertyOf dt:CDCoding.displayName"
          }
        ]
      },
      {
        "id": "AllergyIntolerance.reaction.manifestation:clinical-findings.coding.userSelected",
        "path": "AllergyIntolerance.reaction.manifestation.coding.userSelected",
        "short": "If this coding was chosen directly by the user",
        "definition": "Indicates that this coding was chosen by a user directly - e.g. off a pick list of available items (codes or displays).",
        "comment": "Amongst a set of alternatives, a directly chosen code is the most appropriate starting point for new translations. There is some ambiguity about what exactly 'directly chosen' implies, and trading partner agreement may be needed to clarify the use of this element and its consequences more completely.",
        "requirements": "This has been identified as a clinical safety criterium - that this exact system/code pair was chosen explicitly, rather than inferred by the system based on some rules or language processing.",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Coding.userSelected",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "boolean"
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          }
        ],
        "isSummary": true,
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "v2",
            "map": "Sometimes implied by being first"
          },
          {
            "identity": "rim",
            "map": "CD.codingRationale"
          },
          {
            "identity": "orim",
            "map": "fhir:Coding.userSelected fhir:mapsTo dt:CDCoding.codingRationale. fhir:Coding.userSelected fhir:hasMap fhir:Coding.userSelected.map. fhir:Coding.userSelected.map a fhir:Map;   fhir:target dt:CDCoding.codingRationale. fhir:Coding.userSelected\\#true a [     fhir:source \"true\";     fhir:target dt:CDCoding.codingRationale\\#O   ]"
          }
        ]
      },
      {
        "id": "AllergyIntolerance.reaction.manifestation:clinical-findings.text",
        "extension": [
          {
            "url": "http://hl7.org/fhir/StructureDefinition/elementdefinition-translatable",
            "valueBoolean": true
          }
        ],
        "path": "AllergyIntolerance.reaction.manifestation.text",
        "short": "Plain text representation of the concept",
        "definition": "A human language representation of the concept as seen/selected/uttered by the user who entered the data and/or which represents the intended meaning of the user.",
        "comment": "Very often the text is the same as a displayName of one of the codings.",
        "requirements": "The codes from the terminologies do not always capture the correct meaning with all the nuances of the human using them, or sometimes there is no appropriate code at all. In these cases, the text is used to capture the full meaning of the source.",
        "min": 0,
        "max": "1",
        "base": {
          "path": "CodeableConcept.text",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "string"
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          }
        ],
        "isSummary": true,
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "v2",
            "map": "C*E.9. But note many systems use C*E.2 for this"
          },
          {
            "identity": "rim",
            "map": "./originalText[mediaType/code=\"text/plain\"]/data"
          },
          {
            "identity": "orim",
            "map": "fhir:CodeableConcept.text rdfs:subPropertyOf dt:CD.originalText"
          }
        ]
      },
      {
        "id": "AllergyIntolerance.reaction.description",
        "path": "AllergyIntolerance.reaction.description",
        "short": "Description of the event as a whole",
        "definition": "Text description about the reaction as a whole, including details of the manifestation if required.",
        "comment": "Use the description to provide any details of a particular event of the occurred reaction such as circumstances, reaction specifics, what happened before/after. Information, related to the event, but not describing a particular care should be captured in the comment field. For example: at the age of four, the patient was given penicillin for strep throat and subsequently developed severe hives.",
        "alias": [
          "Narrative",
          "Text"
        ],
        "min": 0,
        "max": "1",
        "base": {
          "path": "AllergyIntolerance.reaction.description",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "string"
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          }
        ],
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "rim",
            "map": "text"
          }
        ]
      },
      {
        "id": "AllergyIntolerance.reaction.onset",
        "path": "AllergyIntolerance.reaction.onset",
        "short": "Date(/time) when manifestations showed",
        "definition": "Record of the date and/or time of the onset of the Reaction.",
        "min": 0,
        "max": "1",
        "base": {
          "path": "AllergyIntolerance.reaction.onset",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "dateTime"
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          }
        ],
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "v2",
            "map": "AL1-6"
          },
          {
            "identity": "rim",
            "map": "effectiveTime.low"
          }
        ]
      },
      {
        "id": "AllergyIntolerance.reaction.severity",
        "path": "AllergyIntolerance.reaction.severity",
        "short": "mild | moderate | severe",
        "definition": "Valutazione clinica della gravità dell'evento di reazione nel suo complesso, considerando potenzialmente più manifestazioni diverse.\r\n\r\nValori Ammessi:\r\n\r\n* mild : Provoca lievi effetti fisiologici.\r\n\r\n* moderate: Provoca effetti fisiologici moderati.\r\n\r\n* severe: Provoca gravi effetti fisiologici.",
        "comment": "Si riconosce che questa valutazione è molto soggettiva. Ci possono essere alcuni ambiti pratici specifici in cui sono state applicate scale oggettive. Le scale oggettive possono essere incluse in questo modello come estensioni.",
        "min": 0,
        "max": "1",
        "base": {
          "path": "AllergyIntolerance.reaction.severity",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "code"
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          }
        ],
        "binding": {
          "extension": [
            {
              "url": "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName",
              "valueString": "AllergyIntoleranceSeverity"
            }
          ],
          "strength": "required",
          "description": "Clinical assessment of the severity of a reaction event as a whole, potentially considering multiple different manifestations.",
          "valueSet": "http://hl7.org/fhir/ValueSet/reaction-event-severity|4.0.1"
        },
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "rim",
            "map": "inboundRelationship[typeCode=SUBJ].source[classCode=OBS, moodCode=EVN, code=SEV, value <= SeverityObservation (Severity Level)]"
          }
        ]
      },
      {
        "id": "AllergyIntolerance.reaction.exposureRoute",
        "extension": [
          {
            "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status",
            "valueCode": "normative"
          },
          {
            "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-normative-version",
            "valueCode": "4.0.0"
          }
        ],
        "path": "AllergyIntolerance.reaction.exposureRoute",
        "short": "How the subject was exposed to the substance",
        "definition": "Identification of the route by which the subject was exposed to the substance.",
        "comment": "Coding of the route of exposure with a terminology should be used wherever possible.",
        "min": 0,
        "max": "1",
        "base": {
          "path": "AllergyIntolerance.reaction.exposureRoute",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "CodeableConcept"
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          }
        ],
        "binding": {
          "extension": [
            {
              "url": "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName",
              "valueString": "RouteOfAdministration"
            }
          ],
          "strength": "example",
          "description": "A coded concept describing the route or physiological path of administration of a therapeutic agent into or onto the body of a subject.",
          "valueSet": "http://hl7.org/fhir/ValueSet/route-codes"
        },
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "v2",
            "map": "CE/CNE/CWE"
          },
          {
            "identity": "rim",
            "map": "CD"
          },
          {
            "identity": "orim",
            "map": "fhir:CodeableConcept rdfs:subClassOf dt:CD"
          },
          {
            "identity": "rim",
            "map": "outBoundRelationship[typeCode=SAS].target[classCode=SBADM, code <= ExposureCode].routeCode"
          }
        ]
      },
      {
        "id": "AllergyIntolerance.reaction.note",
        "extension": [
          {
            "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status",
            "valueCode": "normative"
          },
          {
            "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-normative-version",
            "valueCode": "4.0.0"
          }
        ],
        "path": "AllergyIntolerance.reaction.note",
        "short": "Text about event not captured in other fields",
        "definition": "Additional text about the adverse reaction event not captured in other fields.",
        "comment": "Use this field to record information indirectly related to a particular event and not captured in the description. For example: Clinical records are no longer available, recorded based on information provided to the patient by her mother and her mother is deceased.",
        "min": 0,
        "max": "*",
        "base": {
          "path": "AllergyIntolerance.reaction.note",
          "min": 0,
          "max": "*"
        },
        "type": [
          {
            "code": "Annotation"
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          }
        ],
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "v2",
            "map": "N/A"
          },
          {
            "identity": "rim",
            "map": "Act"
          },
          {
            "identity": "rim",
            "map": "subjectOf.observationEvent[code=\"annotation\"].value"
          }
        ]
      }
    ]
  },
  "differential": {
    "element": [
      {
        "id": "AllergyIntolerance.id",
        "path": "AllergyIntolerance.id",
        "short": "Id logico di questo artefatto",
        "definition": "L'id logico della risorsa, utilizzato nell'URL della risorsa. Una volta assegnato, questo valore non cambia mai.",
        "comment": "L'unica volta che una risorsa non ha un id è quando viene inviata al server tramite un'operazione di creazione."
      },
      {
        "id": "AllergyIntolerance.type",
        "path": "AllergyIntolerance.type",
        "short": "Allergia o intolleranza",
        "definition": "Identificazione del meccanismo fisiologico alla base del rischio di reazione.\r\n\r\nValori ammessi:\r\n\r\n* allergy: Propensione a reazioni di ipersensibilità a una sostanza. Queste reazioni sono in genere l'ipersensibilità di tipo I e altre reazioni \"allergiche\", tra cui la pseudoallergia.\r\n\r\n* intolerance: Una propensione a reazioni avverse a una sostanza che non è giudicata allergica o \"simile all'allergia\". Queste reazioni sono tipicamente (ma non necessariamente) non immunitarie. Sono in qualche misura idiosincratiche e/o specifiche per il paziente (cioè non sono una reazione che ci si aspetta si verifichi nella maggior parte o in tutti i pazienti in circostanze simili).",
        "comment": "Le reazioni allergiche (tipicamente immuno-mediate) sono state tradizionalmente considerate un indicatore di potenziale escalation verso un rischio futuro significativo. Le conoscenze attuali suggeriscono che alcune reazioni precedentemente ritenute immuno-mediate sono, in realtà, non immuni, ma in alcuni casi possono ancora rappresentare un rischio per la vita. Si riconosce che molti medici potrebbero non essere in grado di distinguere il meccanismo di una particolare reazione. Spesso il termine \"allergia\" è usato in modo piuttosto generico e può sovrapporsi all'uso di \"intolleranza\" - in pratica i confini tra questi due concetti potrebbero non essere ben definiti o compresi. Questo dato viene comunque incluso perché molti sistemi preesistenti hanno rilevato questo attributo. I test immunologici possono fornire prove a sostegno della base della reazione e della sostanza causale, ma nessun test è sensibile o specifico al 100% per la sensibilità a una particolare sostanza. Se, come spesso accade, non è chiaro se la reazione sia dovuta a un'allergia o a un'intolleranza, l'elemento type deve essere omesso dalla risorsa."
      },
      {
        "id": "AllergyIntolerance.category",
        "path": "AllergyIntolerance.category",
        "definition": "Categoria della sostanza identificata.\r\n\r\nValori ammessi: \r\n\r\n* food: Qualsiasi sostanza consumata per fornire un supporto nutrizionale all'organismo.\r\n\r\n* medication: Sostanze somministrate per ottenere un effetto fisiologico.\r\n\r\n* environment: Tutte le sostanze presenti nell'ambiente, comprese quelle non già classificate come alimenti, farmaci o sostanze biologiche.\r\n\r\n* biologic: Un preparato sintetizzato da organismi viventi o dai loro prodotti, in particolare una proteina umana o animale, come un ormone o un'antitossina, utilizzato come agente diagnostico, preventivo o terapeutico. Esempi di farmaci biologici sono: i vaccini; gli estratti allergenici, utilizzati sia per la diagnosi che per il trattamento (ad esempio, le iniezioni di allergia); le terapie geniche; le terapie cellulari. Esistono altri prodotti biologici, come i tessuti, che non sono tipicamente associati alle allergie.",
        "comment": "Questo dato è stato incluso perché attualmente viene rilevato in alcuni sistemi clinici. Questo dato può essere ricavato dalla sostanza in cui si utilizzano sistemi di codifica ed è effettivamente ridondante in tale situazione.  Quando si effettua una ricerca per categoria, considerare le implicazioni delle risorse Allergia-Intolleranza senza categoria.  Ad esempio, quando si effettua una ricerca su categoria = farmaco, le allergie ai farmaci che non hanno una categoria valorizzata non verranno restituite.  Fare riferimento a [search](search.html) per maggiori informazioni su come cercare la categoria con un modificatore :missing per ottenere le allergie che non hanno una categoria.  Inoltre, la categoria deve essere usata con cautela perché può essere soggettiva a seconda del mittente."
      },
      {
        "id": "AllergyIntolerance.code",
        "path": "AllergyIntolerance.code",
        "short": "Codice che identifica l'allergia o l'intolleranza",
        "definition": "Codice per una dichiarazione di allergia o intolleranza (positiva o negata/esclusa).  \r\n\r\nPuò trattarsi di un codice per una sostanza o un prodotto farmaceutico considerato responsabile del rischio di reazione avversa (ad esempio, \"Lattice\"), di una condizione di allergia o intolleranza (ad esempio, \"Allergia al lattice\"), o di un codice negato/escluso per una sostanza o una classe specifica (ad esempio, \"Nessuna allergia al lattice\") o di una dichiarazione negata generale o categorica (ad esempio, \"Nessuna allergia nota\", \"Nessuna allergia nota ai farmaci\").\r\n\r\nNota: la sostanza per una reazione specifica può essere diversa dalla sostanza identificata come causa del rischio, ma deve essere coerente con essa. Ad esempio, può trattarsi di una sostanza più specifica (ad esempio un farmaco di marca) o di un prodotto composito che include la sostanza identificata. Deve essere clinicamente sicuro elaborare solo il \"codice\" e ignorare la \"reazione.sostanza\".  Se un sistema ricevente non è in grado di confermare che AllergyIntolerance.reaction.substance rientra nell'ambito semantico di AllergyIntolerance.code, allora il sistema ricevente deve ignorare AllergyIntolerance.reaction.substance.",
        "comment": "Si raccomanda vivamente che questo elemento sia popolato utilizzando una terminologia, ove possibile. Ad esempio, alcune terminologie utilizzate sono RxNorm, SNOMED CT, DM+D, NDFRT, ICD-9, IDC-10, UNII e ATC. Il testo semplice deve essere utilizzato solo se non è disponibile una terminologia appropriata. Ulteriori dettagli possono essere specificati nel testo.\r\n\r\nQuando viene specificato un codice di sostanza o prodotto per l'elemento \"codice\", il contesto semantico \"predefinito\" è che si tratta di una dichiarazione positiva di una condizione di allergia o intolleranza (a seconda del valore dell'elemento \"tipo\", se presente) alla sostanza/prodotto specificato.  Nel corrispondente modello SNOMED CT di allergia, la sostanza/prodotto specificato è il target (destinazione) della relazione \"agente causale\".\r\n\r\nL'estensione \"substanceExposureRisk\" è disponibile come alternativa strutturata e più flessibile all'elemento \"code\" per la formulazione di dichiarazioni di allergia o intolleranza positive o negative.  Questa estensione offre la possibilità di fare dichiarazioni di \"nessuna allergia nota\" (o \"nessun rischio di reazione avversa\") in merito a qualsiasi sostanza/prodotto codificato (compresi i casi in cui non esiste un concetto precoordinato di \"nessuna allergia a x\" per quella sostanza/prodotto).  Se è presente l'estensione \"substanceExposureRisk\", l'elemento AllergyIntolerance.code DEVE essere omesso."
      },
      {
        "id": "AllergyIntolerance.code.coding",
        "path": "AllergyIntolerance.code.coding",
        "slicing": {
          "discriminator": [
            {
              "type": "value",
              "path": "system"
            }
          ],
          "rules": "closed"
        },
        "short": "Codice definito da un sistema terminologico",
        "definition": "Un riferimento a un codice definito da un sistema terminologico.",
        "comment": "I codici possono essere definiti in modo molto casuale in enumerazioni o elenchi di codici, fino a definizioni molto formali come SNOMED CT - si vedano i Core Principles di HL7 v3 per maggiori informazioni.  L'ordine dei codici non è definito e NON DEVE essere usato per dedurre il significato. In generale, al massimo uno solo dei valori di codifica sarà etichettato come UserSelected = true."
      },
      {
        "id": "AllergyIntolerance.code.coding:medicationKnowledge-substance",
        "path": "AllergyIntolerance.code.coding",
        "sliceName": "medicationKnowledge-substance",
        "short": "Codice definito da un sistema terminologico",
        "definition": "Un riferimento a un codice definito da un sistema terminologico.",
        "comment": "I codici possono essere definiti in modo molto casuale in enumerazioni o elenchi di codici, fino a definizioni molto formali come SNOMED CT - si vedano i Core Principles di HL7 v3 per maggiori informazioni.  L'ordine dei codici non è definito e NON DEVE essere usato per dedurre il significato. In generale, al massimo uno solo dei valori di codifica sarà etichettato come UserSelected = true."
      },
      {
        "id": "AllergyIntolerance.code.coding:medicationKnowledge-substance.system",
        "path": "AllergyIntolerance.code.coding.system",
        "short": "Identità del sistema terminologico",
        "definition": "L'identificazione del sistema di codice che definisce il significato del simbolo nel codice.",
        "comment": "L'URI può essere un OID (urn:oid:...) o un UUID (urn:uuid:...).  Gli OID e gli UUID DEVONO essere riferimenti al registro OID di HL7. Altrimenti, l'URI deve provenire dall'elenco di URI speciali definiti da HL7 per FHIR o deve fare riferimento a qualche definizione che stabilisca il sistema in modo chiaro e non ambiguo.",
        "fixedUri": "http://farmadati.eng.it/FHIR/schema/medicationKnowledge-substance"
      },
      {
        "id": "AllergyIntolerance.code.coding:atc",
        "path": "AllergyIntolerance.code.coding",
        "sliceName": "atc",
        "short": "Codice definito da un sistema terminologico",
        "definition": "Un riferimento a un codice definito da un sistema terminologico.",
        "comment": "I codici possono essere definiti in modo molto casuale in enumerazioni o elenchi di codici, fino a definizioni molto formali come SNOMED CT - si vedano i Core Principles di HL7 v3 per maggiori informazioni.  L'ordine dei codici non è definito e NON DEVE essere usato per dedurre il significato. In generale, al massimo uno solo dei valori di codifica sarà etichettato come UserSelected = true."
      },
      {
        "id": "AllergyIntolerance.code.coding:atc.system",
        "path": "AllergyIntolerance.code.coding.system",
        "short": "Identità del sistema terminologico",
        "definition": "L'identificazione del sistema di codice che definisce il significato del simbolo nel codice.",
        "comment": "L'URI può essere un OID (urn:oid:...) o un UUID (urn:uuid:...).  Gli OID e gli UUID DEVONO essere riferimenti al registro OID di HL7. Altrimenti, l'URI deve provenire dall'elenco di URI speciali definiti da HL7 per FHIR o deve fare riferimento a qualche definizione che stabilisca il sistema in modo chiaro e non ambiguo.",
        "fixedUri": "urn:uri:https://www.whocc.no/atc"
      },
      {
        "id": "AllergyIntolerance.code.coding:absent-unknown-uv-ips",
        "path": "AllergyIntolerance.code.coding",
        "sliceName": "absent-unknown-uv-ips",
        "short": "Codice definito da un sistema terminologico",
        "definition": "Un riferimento a un codice definito da un sistema terminologico.",
        "comment": "I codici possono essere definiti in modo molto casuale in enumerazioni o elenchi di codici, fino a definizioni molto formali come SNOMED CT - si vedano i Core Principles di HL7 v3 per maggiori informazioni.  L'ordine dei codici non è definito e NON DEVE essere usato per dedurre il significato. In generale, al massimo uno solo dei valori di codifica sarà etichettato come UserSelected = true."
      },
      {
        "id": "AllergyIntolerance.code.coding:absent-unknown-uv-ips.system",
        "path": "AllergyIntolerance.code.coding.system",
        "short": "Identità del sistema terminologico",
        "definition": "L'identificazione del sistema di codice che definisce il significato del simbolo nel codice.",
        "comment": "L'URI può essere un OID (urn:oid:...) o un UUID (urn:uuid:...).  Gli OID e gli UUID DEVONO essere riferimenti al registro OID di HL7. Altrimenti, l'URI deve provenire dall'elenco di URI speciali definiti da HL7 per FHIR o deve fare riferimento a qualche definizione che stabilisca il sistema in modo chiaro e non ambiguo.",
        "fixedUri": "http://hl7.org/fhir/uv/ips/CodeSystem/absent-unknown-uv-ips"
      },
      {
        "id": "AllergyIntolerance.patient",
        "path": "AllergyIntolerance.patient",
        "short": "A chi è rivolta la sensibilità",
        "definition": "Il paziente affetto da allergia o intolleranza.",
        "comment": "I riferimenti DEVONO essere un riferimento a una risorsa FHIR effettiva e DEVONO essere risolvibili (consentendo il controllo dell'accesso, la non disponibilità temporanea, ecc.) La risoluzione può avvenire tramite recupero dall'URL o, se applicabile per tipo di risorsa, trattando un riferimento assoluto come un URL canonico e cercandolo in un registro/repository locale.",
        "type": [
          {
            "code": "Reference",
            "targetProfile": [
              "https://eng.it/fhir/StructureDefinition/Patient_Eng"
            ]
          }
        ]
      },
      {
        "id": "AllergyIntolerance.encounter",
        "path": "AllergyIntolerance.encounter",
        "type": [
          {
            "code": "Reference",
            "targetProfile": [
              "https://eng.it/fhir/StructureDefinition/Encounter_ADT_Eng",
              "https://eng.it/fhir/StructureDefinition/Encounter_AMB_Eng",
              "https://eng.it/fhir/StructureDefinition/Encounter_WL_Eng",
              "https://eng.it/fhir/StructureDefinition/Encounter_ER_Eng"
            ]
          }
        ]
      },
      {
        "id": "AllergyIntolerance.onset[x]",
        "path": "AllergyIntolerance.onset[x]",
        "short": "Quando è stata identificata un'allergia o un'intolleranza",
        "definition": "Data, ora o età stimata o effettiva in cui è stata identificata l'allergia o l'intolleranza.",
        "type": [
          {
            "code": "dateTime"
          },
          {
            "code": "Period"
          },
          {
            "code": "string"
          }
        ]
      },
      {
        "id": "AllergyIntolerance.recorder",
        "path": "AllergyIntolerance.recorder",
        "short": "Chi ha registrato la sensibilità",
        "definition": "Persona che ha registrato la registrazione e si assume la responsabilità del suo contenuto.",
        "comment": "I riferimenti DEVONO essere un riferimento a una risorsa FHIR effettiva e DEVONO essere risolvibili (consentendo il controllo dell'accesso, la non disponibilità temporanea, ecc.) La risoluzione può avvenire tramite recupero dall'URL o, se applicabile per tipo di risorsa, trattando un riferimento assoluto come un URL canonico e cercandolo in un registro/repository locale.",
        "type": [
          {
            "code": "Reference",
            "targetProfile": [
              "https://eng.it/fhir/StructureDefinition/Practitioner_Eng"
            ]
          }
        ]
      },
      {
        "id": "AllergyIntolerance.reaction",
        "path": "AllergyIntolerance.reaction",
        "short": "Reazione avversa Eventi legati all'esposizione alla sostanza",
        "definition": "Dettagli su ciascun evento avverso legato all'esposizione alla sostanza identificata."
      },
      {
        "id": "AllergyIntolerance.reaction.manifestation",
        "path": "AllergyIntolerance.reaction.manifestation",
        "slicing": {
          "discriminator": [
            {
              "type": "value",
              "path": "coding.system"
            }
          ],
          "rules": "open"
        },
        "short": "Sintomi/segni clinici associati all'evento",
        "definition": "Sintomi e/o segni clinici osservati o associati all'evento avverso.",
        "comment": "La manifestazione può essere espressa come una singola parola, una frase o una breve descrizione. Ad esempio: nausea, eruzione cutanea o nessuna reazione. È preferibile che la manifestazione sia codificata con una terminologia, ove possibile. I valori qui inseriti possono essere utilizzati per essere visualizzati su una schermata dell'applicazione come parte di un elenco di reazioni avverse, come raccomandato nelle linee guida CUI del NHS britannico.  Le terminologie comunemente utilizzate includono, ma non solo, SNOMED CT o ICD10."
      },
      {
        "id": "AllergyIntolerance.reaction.manifestation:clinical-findings",
        "path": "AllergyIntolerance.reaction.manifestation",
        "sliceName": "clinical-findings",
        "short": "Sintomi/segni clinici associati all'evento",
        "definition": "Sintomi e/o segni clinici osservati o associati all'evento avverso.",
        "comment": "La manifestazione può essere espressa come una singola parola, una frase o una breve descrizione. Ad esempio: nausea, eruzione cutanea o nessuna reazione. È preferibile che la manifestazione sia codificata con una terminologia, ove possibile. I valori qui inseriti possono essere utilizzati per essere visualizzati su una schermata dell'applicazione come parte di un elenco di reazioni avverse, come raccomandato nelle linee guida CUI del NHS britannico.  Le terminologie comunemente utilizzate includono, ma non solo, SNOMED CT o ICD10."
      },
      {
        "id": "AllergyIntolerance.reaction.manifestation:clinical-findings.coding",
        "path": "AllergyIntolerance.reaction.manifestation.coding",
        "short": "Codice definito da un sistema terminologico",
        "definition": "Un riferimento a un codice definito da un sistema terminologico.",
        "comment": "I codici possono essere definiti in modo molto casuale in enumerazioni o elenchi di codici, fino a definizioni molto formali come SNOMED CT - si vedano i Core Principles di HL7 v3 per maggiori informazioni.  L'ordine dei codici non è definito e NON DEVE essere usato per dedurre il significato. In generale, al massimo uno solo dei valori di codifica sarà etichettato come UserSelected = true."
      },
      {
        "id": "AllergyIntolerance.reaction.manifestation:clinical-findings.coding.system",
        "path": "AllergyIntolerance.reaction.manifestation.coding.system",
        "short": "Identità del sistema terminologico",
        "definition": "L'identificazione del sistema di codice che definisce il significato del simbolo nel codice.",
        "comment": "L'URI può essere un OID (urn:oid:...) o un UUID (urn:uuid:...).  Gli OID e gli UUID DEVONO essere riferimenti al registro OID di HL7. Altrimenti, l'URI deve provenire dall'elenco di URI speciali definiti da HL7 per FHIR o deve fare riferimento a qualche definizione che stabilisca il sistema in modo chiaro e non ambiguo.",
        "fixedUri": "http://hl7.org/fhir/CodeSystem/clinical-findings"
      },
      {
        "id": "AllergyIntolerance.reaction.severity",
        "path": "AllergyIntolerance.reaction.severity",
        "short": "mild | moderate | severe",
        "definition": "Valutazione clinica della gravità dell'evento di reazione nel suo complesso, considerando potenzialmente più manifestazioni diverse.\r\n\r\nValori Ammessi:\r\n\r\n* mild : Provoca lievi effetti fisiologici.\r\n\r\n* moderate: Provoca effetti fisiologici moderati.\r\n\r\n* severe: Provoca gravi effetti fisiologici.",
        "comment": "Si riconosce che questa valutazione è molto soggettiva. Ci possono essere alcuni ambiti pratici specifici in cui sono state applicate scale oggettive. Le scale oggettive possono essere incluse in questo modello come estensioni."
      }
    ]
  }
}