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Source1

{
  "resourceType": "StructureDefinition",
  "id": "nfdi4health-ex-mds-study-non-interventional",
  "url": "https://www.nfdi4health.de/fhir/metadataschema/StructureDefinition/nfdi4health-ex-mds-study-non-interventional",
  "name": "NFDI4Health_EX_MDS_Study_Non_Interventional",
  "title": "NFDI4Health EX MDS Study Non Interventional",
  "status": "draft",
  "publisher": "NFDI4Health",
  "contact": [
    {
      "telecom": [
        {
          "system": "url",
          "value": "https://www.nfdi4health.de"
        }
      ]
    }
  ],
  "description": "Group of items providing information about non interventional studys",
  "fhirVersion": "4.0.1",
  "mapping": [
    {
      "identity": "rim",
      "uri": "http://hl7.org/v3",
      "name": "RIM Mapping"
    },
    {
      "identity": "NFDI4Health",
      "name": "NFDI4Health to FHIR Mapping"
    }
  ],
  "kind": "complex-type",
  "abstract": false,
  "context": [
    {
      "type": "element",
      "expression": "ResearchStudy"
    }
  ],
  "type": "Extension",
  "baseDefinition": "http://hl7.org/fhir/StructureDefinition/Extension",
  "derivation": "constraint",
  "differential": {
    "element": [
      {
        "id": "Extension",
        "path": "Extension",
        "short": "Non-interventional aspects of the [RESOURCE]",
        "definition": "Group of items providing information about specific non-interventional aspects of the [RESOURCE].",
        "max": "1",
        "mapping": [
          {
            "identity": "NFDI4Health",
            "map": "Design.nonInterventional"
          }
        ]
      },
      {
        "id": "Extension.extension:timePerspectives",
        "path": "Extension.extension",
        "sliceName": "timePerspectives",
        "short": "Temporal design",
        "definition": "Temporal design of the study, i.e. the  observation period to time of participant enrollment.",
        "comment": "Is it a retrospective, prospective or cross-sectional study?",
        "min": 0,
        "max": "1",
        "mapping": [
          {
            "identity": "NFDI4Health",
            "map": "Design.nonInterventional.timePerspectives"
          }
        ]
      },
      {
        "id": "Extension.extension:timePerspectives.extension",
        "path": "Extension.extension.extension",
        "max": "0"
      },
      {
        "id": "Extension.extension:timePerspectives.url",
        "path": "Extension.extension.url",
        "fixedUri": "timePerspectives"
      },
      {
        "id": "Extension.extension:timePerspectives.value[x]",
        "path": "Extension.extension.value[x]",
        "type": [
          {
            "code": "Coding"
          }
        ],
        "binding": {
          "strength": "required",
          "valueSet": "https://www.nfdi4health.de/fhir/metadataschema/ValueSet/nfdi4health-vs-mds-study-time-perspectives-nci",
          "description": "Value set defining codes to specify the time perspective of a study in a ResearchStudy resource."
        }
      },
      {
        "id": "Extension.extension:targetFollowUpDuration",
        "path": "Extension.extension",
        "sliceName": "targetFollowUpDuration",
        "min": 0,
        "max": "1",
        "type": [
          {
            "code": "Extension",
            "profile": [
              "https://www.nfdi4health.de/fhir/metadataschema/StructureDefinition/nfdi4health-ex-mds-study-target-followup-duration"
            ]
          }
        ]
      },
      {
        "id": "Extension.extension:biospecimenRetention",
        "path": "Extension.extension",
        "sliceName": "biospecimenRetention",
        "short": "Biosamples retained in a biorepository",
        "definition": "Indication whether samples of biomaterials from participants are retained in a biorepository.",
        "comment": "Short input help: Select all that apply.",
        "min": 0,
        "max": "*",
        "mapping": [
          {
            "identity": "NFDI4Health",
            "map": "Design.nonInterventional.biospecimenRetention"
          }
        ]
      },
      {
        "id": "Extension.extension:biospecimenRetention.extension",
        "path": "Extension.extension.extension",
        "max": "0"
      },
      {
        "id": "Extension.extension:biospecimenRetention.url",
        "path": "Extension.extension.url",
        "fixedUri": "biospecimenRetention"
      },
      {
        "id": "Extension.extension:biospecimenRetention.value[x]",
        "path": "Extension.extension.value[x]",
        "type": [
          {
            "code": "Coding"
          }
        ],
        "binding": {
          "strength": "required",
          "valueSet": "https://www.nfdi4health.de/fhir/metadataschema/ValueSet/nfdi4health-vs-mds-study-biospecimen-retention-nci",
          "description": "Value set defining codes to specify which biosamples are retained in a biorepository."
        }
      },
      {
        "id": "Extension.extension:biospecimenDescription",
        "path": "Extension.extension",
        "sliceName": "biospecimenDescription",
        "short": "Specific types of retained biosamples",
        "definition": "Additional information about retained biosamples, i.e. an indication of the specific types of retained biospecimens (e.g. blood, serum, urine, etc.).",
        "comment": "You can provide here specific types of retained biosamples (e.g. blood, serum, urine, etc.).",
        "min": 0,
        "max": "1",
        "example": [
          {
            "label": "Example of a specific type of a retained biosample",
            "valueString": "blood"
          }
        ],
        "mapping": [
          {
            "identity": "NFDI4Health",
            "map": "Design.nonInterventional.biospecimenDescription"
          }
        ]
      },
      {
        "id": "Extension.extension:biospecimenDescription.extension",
        "path": "Extension.extension.extension",
        "max": "0"
      },
      {
        "id": "Extension.extension:biospecimenDescription.url",
        "path": "Extension.extension.url",
        "fixedUri": "biospecimenDescription"
      },
      {
        "id": "Extension.extension:biospecimenDescription.value[x]",
        "path": "Extension.extension.value[x]",
        "type": [
          {
            "code": "string"
          }
        ]
      },
      {
        "id": "Extension.url",
        "path": "Extension.url",
        "fixedUri": "https://www.nfdi4health.de/fhir/metadataschema/StructureDefinition/nfdi4health-ex-mds-study-non-interventional"
      },
      {
        "id": "Extension.value[x]",
        "path": "Extension.value[x]",
        "max": "0"
      }
    ]
  }
}