FHIR IG analytics| Package | de.netzwerk-universitaetsmedizin.ebm-cpg |
| Resource Type | Bundle |
| Id | Bundle-COVID19IntensiveCareTreatmentGuidelineBundle.json |
| FHIR Version | R5 |
No resources found
No resources found
No narrative content found in resource
FHIR
FHIRsmith{
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"id": "COVID19IntensiveCareTreatmentGuidelineBundle",
"meta": {
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{
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"text": {
"status": "generated",
"div": "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Composition_COVID19IntensiveCareTreatmentGuideline\"> </a><p class=\"res-header-id\"><b>Generated Narrative: Composition COVID19IntensiveCareTreatmentGuideline</b></p><a name=\"COVID19IntensiveCareTreatmentGuideline\"> </a><a name=\"hcCOVID19IntensiveCareTreatmentGuideline\"> </a><a name=\"COVID19IntensiveCareTreatmentGuideline-en-US\"> </a><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\"/><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-guideline.html\">Clinical Practice Guideline</a></p></div><p><b>identifier</b>: Resource identifier/113-001</p><p><b>version</b>: 7.0</p><p><b>status</b>: Final</p><p><b>type</b>: <span title=\"Codes:{https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/CodeSystem/ceosys-code-system clinical-practice-guideline}, {https://data.cochrane.org/concepts/ e07eN1w1Rwswg4}\">Guidelines</span></p><p><b>category</b>: <span title=\"Codes:{https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/CodeSystem/cs-guideline-stage-classification S3}\">Evidence- and consensus-based guideline</span></p><p><b>date</b>: 2022-03-01</p><p><b>author</b>: <a href=\"Organization-AWMFOrganization.html\">Organization Arbeitsgemeinschaft der Wissenschaftlichen Medizinischen Fachgesellschaften (AWMF) e.V.</a></p><p><b>title</b>: Empfehlungen zur stationären Therapie von Patienten mit COVID-19 - Living Guideline</p><h3>RelatesTos</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Type</b></td><td><b>ResourceReference</b></td></tr><tr><td style=\"display: none\">*</td><td>Citation</td><td><a href=\"Citation-COVID19IntensiveCareTreatmentGuidelineCitation.html\">Citation COVID19_Intensive_Care_Treatment_Guideline</a></td></tr></table></div>"
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"date": "2022-03-01",
"author": [
{
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],
"title": "Empfehlungen zur stationären Therapie von Patienten mit COVID-19 - Living Guideline",
"relatesTo": [
{
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"resourceReference": {
"reference": "Citation/COVID19IntensiveCareTreatmentGuidelineCitation"
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],
"section": [
{
"title": "Stationäre Therapie von COVID-19 Patienten",
"code": {
"coding": [
{
"system": "https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/CodeSystem/ceosys-code-system",
"code": "guideline-recommendation",
"display": "Clinical practice guideline recommendation"
}
]
},
"focus": {
"reference": "PlanDefinition/COVID19VentilatedPatientsDexamethasoneApplicationPlan"
},
"text": {
"status": "generated",
"div": "<div xmlns=\"http://www.w3.org/1999/xhtml\"><strong>Systemische Steroide:</strong> Bei Patienten mit COVID-19- und Sauerstoff-Bedarf (Niedrigfluss-Sauerstoff-Insufflation, High-Flow Nasal Cannula, Nichtinvasive Beatmung/CPAP, invasive Beatmung) soll eine Therapie mit systemischen Kortikosteroiden erfolgen. Die Therapie sollte mit 6 mg Dexamethason p.o. oder i.v. über zehn Tage erfolgen.</div>"
}
},
{
"title": "Stationäre Therapie von COVID-19 Patienten",
"code": {
"coding": [
{
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"display": "Clinical practice guideline recommendation"
}
]
},
"focus": {
"reference": "PlanDefinition/COVID19NonVentilatedPatientsDexamethasoneApplicationPlan"
},
"text": {
"status": "generated",
"div": "<div xmlns=\"http://www.w3.org/1999/xhtml\"><strong>Systemische Steroide:</strong> Bei Patienten mit moderater Erkrankung (hospitalisiert ohne Notwendigkeit von Niedrigfluss-Sauerstoff-Insufflation) soll keine Therapie mit systemischen Kortikosteroiden erfolgen.</div>"
}
}
]
}
},
{
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"status": "generated",
"div": "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Citation_COVID19IntensiveCareTreatmentGuidelineCitation\"> </a><p class=\"res-header-id\"><b>Generated Narrative: Citation COVID19IntensiveCareTreatmentGuidelineCitation</b></p><a name=\"COVID19IntensiveCareTreatmentGuidelineCitation\"> </a><a name=\"hcCOVID19IntensiveCareTreatmentGuidelineCitation\"> </a><a name=\"COVID19IntensiveCareTreatmentGuidelineCitation-en-US\"> </a><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\"/><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-guideline-citation.html\">Guideline Citation</a></p></div><p><b>name</b>: COVID19_Intensive_Care_Treatment_Guideline</p><p><b>status</b>: Active</p><blockquote><p><b>citedArtifact</b></p><p><b>identifier</b>: <code>https://www.awmf.org/</code>/113-001</p><h3>Versions</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Value</b></td></tr><tr><td style=\"display: none\">*</td><td>7.0</td></tr></table><p><b>currentState</b>: <span title=\"Codes:{http://hl7.org/fhir/cited-artifact-status-type active}\">Active</span></p><h3>Titles</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Text</b></td></tr><tr><td style=\"display: none\">*</td><td><div><p>S3-Leitlinie Stationäre Therapie von COVID-19 Patienten</p>\n</div></td></tr></table><h3>WebLocations</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Url</b></td></tr><tr><td style=\"display: none\">*</td><td><a href=\"https://www.awmf.org/leitlinien/detail/ll/113-001.html\">https://www.awmf.org/leitlinien/detail/ll/113-001.html</a></td></tr></table><h3>Classifications</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Type</b></td><td><b>Classifier</b></td></tr><tr><td style=\"display: none\">*</td><td><span title=\"Codes:{http://hl7.org/fhir/cited-artifact-classification-type publication-type}\">Publication Type</span></td><td><span title=\"Codes:{https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/CodeSystem/ceosys-code-system clinical-practice-guideline}\">Clinical practice guideline</span></td></tr></table></blockquote></div>"
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{
"fullUrl": "https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/guidelines/covid19-intensive-care-treatment/dexamethasone/recommendation",
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"status": "extensions",
"div": "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"PlanDefinition_COVID19DexamethasoneApplication\"> </a><p class=\"res-header-id\"><b>Generated Narrative: PlanDefinition COVID19DexamethasoneApplication</b></p><a name=\"COVID19DexamethasoneApplication\"> </a><a name=\"hcCOVID19DexamethasoneApplication\"> </a><a name=\"COVID19DexamethasoneApplication-en-US\"> </a><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\"/><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-recommendation.html\">Recommendation</a></p></div><p><b>knowledgeCapability</b>: computable</p><p><b>knowledgeRepresentationLevel</b>: structured</p><blockquote><p><b>Action Combination Method</b></p><ul><li>method: <span title=\"Codes:{https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/CodeSystem/cs-action-combination-method one-or-more}\">One or More</span></li></ul></blockquote><p><b>url</b>: <a href=\"PlanDefinition-COVID19DexamethasoneApplication.html\">PlanDefinition Dexamethasone Application</a></p><p><b>version</b>: 4.0</p><p><b>name</b>: Dexamethasone_Application</p><p><b>title</b>: Dexamethasone Application</p><p><b>type</b>: <span title=\"Codes:{http://terminology.hl7.org/CodeSystem/plan-definition-type workflow-definition}\">Workflow Definition</span></p><p><b>status</b>: Active</p><p><b>experimental</b>: true</p><p><b>subject</b>: <a href=\"EvidenceVariable-PopulationCOVID19Ventilated.html\">Population_COVID19_Ventilated</a></p><p><b>date</b>: 2021-12-12</p><p><b>publisher</b>: CPGonEBMonFHIR</p><p><b>description</b>: </p><div><p>Application of Dexamethasone for ventilated patients only</p>\n</div><h3>RelatedArtifacts</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Type</b></td><td><b>Classifier</b></td><td><b>ResourceReference</b></td></tr><tr><td style=\"display: none\">*</td><td>Justification</td><td><span title=\"Codes:{https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/CodeSystem/ceosys-code-system recommendation-rating}\">Recommendation rating</span></td><td><a href=\"ArtifactAssessment-DexamethasoneRecommendationJustification.html\">ArtifactAssessment: extension = v4.0,active; date = 2020-01-03; artifact[x] = ->PlanDefinition Dexamethasone Application in ventilated COVID-19 patients</a></td></tr><tr><td style=\"display: none\">*</td><td>Citation</td><td><span title=\"Codes:{https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/CodeSystem/ceosys-code-system guideline-recommendation}\">Clinical practice guideline recommendation</span></td><td><a href=\"Citation-DexamethasoneRecommendationCitation.html\">Citation DexamethasoneRecommendationCitation</a></td></tr><tr><td style=\"display: none\">*</td><td>Citation</td><td><span title=\"Codes:{https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/CodeSystem/ceosys-code-system clinical-practice-guideline}\">Clinical practice guideline</span></td><td><a href=\"Citation-COVID19IntensiveCareTreatmentGuidelineCitation.html\">Citation COVID19_Intensive_Care_Treatment_Guideline</a></td></tr></table><blockquote><p><b>action</b></p><p><b>title</b>: Dexamethasone Application</p><p><b>description</b>: </p><div><p>Application of Dexamethasone: 6 mg once per day for 10 days p.o. or i.v. for ventilated COVID-19 patients</p>\n</div><p><b>code</b>: <span title=\"Codes:{http://hl7.org/fhir/uv/cpg/CodeSystem/cpg-common-process guideline-based-care}\">Guideline-based Care</span></p><p><b>definition</b>: <a href=\"PlanDefinition-COVID19VentilatedPatientsDexamethasoneApplicationPlan.html\">Dexamethasone Application in ventilated COVID-19 patients</a></p></blockquote><blockquote><p><b>action</b></p><p><b>title</b>: No Dexamethasone Application</p><p><b>description</b>: </p><div><p>No Dexamethasone Application for non-ventilated COVID-19 patients</p>\n</div><p><b>code</b>: <span title=\"Codes:{http://hl7.org/fhir/uv/cpg/CodeSystem/cpg-common-process guideline-based-care}\">Guideline-based Care</span></p><p><b>definition</b>: <a href=\"PlanDefinition-COVID19NonVentilatedPatientsDexamethasoneApplicationPlan.html\">No Dexamethasone Application for non-ventilated COVID-19 patients</a></p></blockquote></div>"
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"url": "https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/covid19-dexamethasone-recommendation",
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"title": "Dexamethasone Application",
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"action": [
{
"title": "Dexamethasone Application",
"description": "Application of Dexamethasone: 6 mg once per day for 10 days p.o. or i.v. for ventilated COVID-19 patients",
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{
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"definitionCanonical": "https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/covid19-ventilated-patients-dexamethasone-application-plan"
},
{
"title": "No Dexamethasone Application",
"description": "No Dexamethasone Application for non-ventilated COVID-19 patients",
"code": {
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{
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"code": "guideline-based-care"
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"definitionCanonical": "https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/covid19-non-ventilated-patients-no-dexamethasone-application-plan"
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"resource": {
"resourceType": "PlanDefinition",
"id": "COVID19VentilatedPatientsDexamethasoneApplicationPlan",
"meta": {
"profile": [
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"text": {
"status": "extensions",
"div": "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"PlanDefinition_COVID19VentilatedPatientsDexamethasoneApplicationPlan\"> </a><p class=\"res-header-id\"><b>Generated Narrative: PlanDefinition COVID19VentilatedPatientsDexamethasoneApplicationPlan</b></p><a name=\"COVID19VentilatedPatientsDexamethasoneApplicationPlan\"> </a><a name=\"hcCOVID19VentilatedPatientsDexamethasoneApplicationPlan\"> </a><a name=\"COVID19VentilatedPatientsDexamethasoneApplicationPlan-en-US\"> </a><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\"/><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-recommendation-plan.html\">Recommendation Plan</a></p></div><p><b>knowledgeCapability</b>: computable</p><p><b>knowledgeRepresentationLevel</b>: structured</p><p><b>partOf</b>: <a href=\"PlanDefinition-COVID19DexamethasoneApplication.html\">Dexamethasone Application</a></p><blockquote><p><b>Action Combination Method</b></p><ul><li>method: <span title=\"Codes:{https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/CodeSystem/cs-action-combination-method exactly}\">Exactly</span></li><li>threshold: 1</li></ul></blockquote><p><b>url</b>: <a href=\"PlanDefinition-COVID19VentilatedPatientsDexamethasoneApplicationPlan.html\">PlanDefinition Dexamethasone Application in ventilated COVID-19 patients</a></p><p><b>version</b>: 4.0</p><p><b>name</b>: Dexamethasone_Application</p><p><b>title</b>: Dexamethasone Application in ventilated COVID-19 patients</p><p><b>type</b>: <span title=\"Codes:{http://terminology.hl7.org/CodeSystem/plan-definition-type eca-rule}\">ECA Rule</span></p><p><b>status</b>: Active</p><p><b>experimental</b>: true</p><p><b>subject</b>: <a href=\"EvidenceVariable-PopulationCOVID19Ventilated.html\">Population_COVID19_Ventilated</a></p><p><b>date</b>: 2021-12-12</p><p><b>publisher</b>: CPGonEBMonFHIR</p><p><b>description</b>: </p><div><p>Application of Dexamethasone: 6 mg once per day for 10 days p.o. or i.v. for ventilated COVID-19 patients</p>\n</div><blockquote><p><b>action</b></p><p><b>code</b>: <span title=\"Codes:{http://snomed.info/sct 18629005}\">Administration of drug or medicament (procedure)</span></p><p><b>definition</b>: <a href=\"Bundle-COVID19IntensiveCareTreatmentGuidelineBundle.html\">DexamethasoneApplicationActionOral</a></p></blockquote><blockquote><p><b>action</b></p><p><b>code</b>: <span title=\"Codes:{http://snomed.info/sct 18629005}\">Administration of drug or medicament (procedure)</span></p><p><b>definition</b>: <a href=\"Bundle-COVID19IntensiveCareTreatmentGuidelineBundle.html\">DexamethasoneApplicationActionIntravenous</a></p></blockquote></div>"
},
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"valueCanonical": "https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/covid19-dexamethasone-recommendation"
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{
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],
"url": "https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/covid19-ventilated-patients-dexamethasone-application-plan",
"version": "4.0",
"name": "Dexamethasone_Application",
"title": "Dexamethasone Application in ventilated COVID-19 patients",
"type": {
"coding": [
{
"system": "http://terminology.hl7.org/CodeSystem/plan-definition-type",
"code": "eca-rule"
}
]
},
"status": "active",
"experimental": true,
"subjectCanonical": "https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/population/Population_COVID19_Ventilated",
"date": "2021-12-12",
"publisher": "CPGonEBMonFHIR",
"description": "Application of Dexamethasone: 6 mg once per day for 10 days p.o. or i.v. for ventilated COVID-19 patients",
"action": [
{
"code": {
"coding": [
{
"system": "http://snomed.info/sct",
"code": "18629005",
"display": "Administration of drug or medicament (procedure)"
}
]
},
"definitionCanonical": "https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/recommendation-action/dexamethasone-application-oral"
},
{
"code": {
"coding": [
{
"system": "http://snomed.info/sct",
"code": "18629005",
"display": "Administration of drug or medicament (procedure)"
}
]
},
"definitionCanonical": "https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/recommendation-action/dexamethasone-application-intravenous"
}
]
}
},
{
"fullUrl": "https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/guidelines/covid19-intensive-care-treatment/dexamethasone/recommendation-plan-non-ventilated-patients",
"resource": {
"resourceType": "PlanDefinition",
"id": "COVID19NonVentilatedPatientsDexamethasoneApplicationPlan",
"meta": {
"profile": [
"https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/StructureDefinition/recommendation-plan"
]
},
"text": {
"status": "extensions",
"div": "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"PlanDefinition_COVID19NonVentilatedPatientsDexamethasoneApplicationPlan\"> </a><p class=\"res-header-id\"><b>Generated Narrative: PlanDefinition COVID19NonVentilatedPatientsDexamethasoneApplicationPlan</b></p><a name=\"COVID19NonVentilatedPatientsDexamethasoneApplicationPlan\"> </a><a name=\"hcCOVID19NonVentilatedPatientsDexamethasoneApplicationPlan\"> </a><a name=\"COVID19NonVentilatedPatientsDexamethasoneApplicationPlan-en-US\"> </a><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\"/><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-recommendation-plan.html\">Recommendation Plan</a></p></div><p><b>knowledgeCapability</b>: computable</p><p><b>knowledgeRepresentationLevel</b>: structured</p><p><b>partOf</b>: <a href=\"PlanDefinition-COVID19DexamethasoneApplication.html\">Dexamethasone Application</a></p><blockquote><p><b>Action Combination Method</b></p><ul><li>method: <span title=\"Codes:{https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/CodeSystem/cs-action-combination-method exactly}\">Exactly</span></li><li>threshold: 1</li></ul></blockquote><p><b>url</b>: <a href=\"PlanDefinition-COVID19NonVentilatedPatientsDexamethasoneApplicationPlan.html\">PlanDefinition No Dexamethasone Application for non-ventilated COVID-19 patients</a></p><p><b>version</b>: 4.0</p><p><b>name</b>: No_Dexamethasone_Application</p><p><b>title</b>: No Dexamethasone Application for non-ventilated COVID-19 patients</p><p><b>type</b>: <span title=\"Codes:{http://terminology.hl7.org/CodeSystem/plan-definition-type eca-rule}\">ECA Rule</span></p><p><b>status</b>: Active</p><p><b>experimental</b>: true</p><p><b>subject</b>: <a href=\"EvidenceVariable-PopulationCOVID19NonVentilated.html\">Population_COVID19_NonVentilated</a></p><p><b>date</b>: 2021-12-12</p><p><b>publisher</b>: CPGonEBMonFHIR</p><p><b>description</b>: </p><div><p>No Dexamethasone Application for non-ventilated COVID19 patients</p>\n</div><h3>Actions</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Definition[x]</b></td></tr><tr><td style=\"display: none\">*</td><td><span title=\"Codes:{http://snomed.info/sct 18629005}\">Administration of drug or medicament (procedure)</span></td><td><a href=\"Bundle-COVID19IntensiveCareTreatmentGuidelineBundle.html\">NoDexamethasoneApplicationActivity</a></td></tr></table></div>"
},
"extension": [
{
"url": "http://hl7.org/fhir/uv/cpg/StructureDefinition/cpg-knowledgeCapability",
"valueCode": "computable"
},
{
"url": "http://hl7.org/fhir/uv/cpg/StructureDefinition/cpg-knowledgeRepresentationLevel",
"valueCode": "structured"
},
{
"url": "http://hl7.org/fhir/uv/cpg/StructureDefinition/cpg-partOf",
"valueCanonical": "https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/covid19-dexamethasone-recommendation"
},
{
"extension": [
{
"url": "method",
"valueCodeableConcept": {
"coding": [
{
"system": "https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/CodeSystem/cs-action-combination-method",
"code": "exactly"
}
]
}
},
{
"url": "threshold",
"valuePositiveInt": 1
}
],
"url": "https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/StructureDefinition/ext-action-combination-method"
}
],
"url": "https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/covid19-non-ventilated-patients-no-dexamethasone-application-plan",
"version": "4.0",
"name": "No_Dexamethasone_Application",
"title": "No Dexamethasone Application for non-ventilated COVID-19 patients",
"type": {
"coding": [
{
"system": "http://terminology.hl7.org/CodeSystem/plan-definition-type",
"code": "eca-rule"
}
]
},
"status": "active",
"experimental": true,
"subjectCanonical": "https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/population/Population_COVID19_NonVentilated",
"date": "2021-12-12",
"publisher": "CPGonEBMonFHIR",
"description": "No Dexamethasone Application for non-ventilated COVID19 patients",
"action": [
{
"code": {
"coding": [
{
"system": "http://snomed.info/sct",
"code": "18629005",
"display": "Administration of drug or medicament (procedure)"
}
]
},
"definitionCanonical": "https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/recommendation-action/no-dexamethasone-application"
}
]
}
},
{
"fullUrl": "https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/guidelines/covid19-intensive-care-treatment/dexamethasone/recommendation-action-oral",
"resource": {
"resourceType": "ActivityDefinition",
"id": "DexamethasoneApplicationActionOral",
"meta": {
"profile": [
"https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/StructureDefinition/drug-administration-action"
]
},
"text": {
"status": "extensions",
"div": "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"ActivityDefinition_DexamethasoneApplicationActionOral\"> </a><p class=\"res-header-id\"><b>Generated Narrative: ActivityDefinition DexamethasoneApplicationActionOral</b></p><a name=\"DexamethasoneApplicationActionOral\"> </a><a name=\"hcDexamethasoneApplicationActionOral\"> </a><a name=\"DexamethasoneApplicationActionOral-en-US\"> </a><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\"/><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-drug-administration-action.html\">Drug Administration Action</a></p></div><p><b>knowledgeCapability</b>: computable</p><p><b>knowledgeRepresentationLevel</b>: structured</p><p><b>url</b>: <a href=\"ActivityDefinition-DexamethasoneApplicationActionOral.html\">ActivityDefinition DexamethasoneApplicationActionOral</a></p><p><b>version</b>: 1.0</p><p><b>name</b>: DexamethasoneApplicationActionOral</p><p><b>status</b>: Active</p><p><b>experimental</b>: true</p><p><b>subject</b>: <span title=\"Codes:{http://hl7.org/fhir/fhir-types Patient}\">Patient</span></p><p><b>publisher</b>: CPGonEBMonFHIR</p><p><b>description</b>: </p><div><p>Application of Dexamethasone: 6 mg once per day for 10 days (oral route)</p>\n</div><p><b>kind</b>: MedicationRequest</p><p><b>code</b>: <span title=\"Codes:{http://snomed.info/sct 18629005}\">Administration of drug or medicament (procedure)</span></p><p><b>product</b>: <span title=\"Codes:{http://snomed.info/sct 372584003}, {http://fhir.de/CodeSystem/bfarm/atc C05AA09}\">Dexamethasone (substance)</span></p><blockquote><p><b>dosage</b></p><p><b>timing</b>: Count 10 times, Duration 10days , Once per 1 day</p><p><b>route</b>: <span title=\"Codes:{http://snomed.info/sct 26643006}\">Oral route</span></p><h3>DoseAndRates</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Dose[x]</b></td><td><b>Rate[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>6 mg<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM codemg = 'mg')</span></td><td>1 /d<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code/d = '/d')</span></td></tr></table></blockquote></div>"
},
"extension": [
{
"url": "http://hl7.org/fhir/uv/cpg/StructureDefinition/cpg-knowledgeCapability",
"valueCode": "computable"
},
{
"url": "http://hl7.org/fhir/uv/cpg/StructureDefinition/cpg-knowledgeRepresentationLevel",
"valueCode": "structured"
}
],
"url": "https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/recommendation-action/dexamethasone-application-oral",
"version": "1.0",
"name": "DexamethasoneApplicationActionOral",
"status": "active",
"experimental": true,
"subjectCodeableConcept": {
"coding": [
{
"system": "http://hl7.org/fhir/fhir-types",
"code": "Patient"
}
]
},
"publisher": "CPGonEBMonFHIR",
"description": "Application of Dexamethasone: 6 mg once per day for 10 days (oral route)",
"kind": "MedicationRequest",
"code": {
"coding": [
{
"system": "http://snomed.info/sct",
"code": "18629005",
"display": "Administration of drug or medicament (procedure)"
}
]
},
"productCodeableConcept": {
"coding": [
{
"system": "http://snomed.info/sct",
"code": "372584003",
"display": "Dexamethasone (substance)"
},
{
"system": "http://fhir.de/CodeSystem/bfarm/atc",
"code": "C05AA09",
"display": "Dexamethason"
}
]
},
"dosage": [
{
"timing": {
"repeat": {
"count": 10,
"duration": 10,
"durationUnit": "d",
"frequency": 1,
"period": 1,
"periodUnit": "d"
}
},
"route": {
"coding": [
{
"system": "http://snomed.info/sct",
"code": "26643006",
"display": "Oral route"
}
]
},
"doseAndRate": [
{
"doseQuantity": {
"value": 6,
"unit": "mg",
"system": "http://unitsofmeasure.org",
"code": "mg"
},
"rateQuantity": {
"value": 1,
"unit": "/d",
"system": "http://unitsofmeasure.org",
"code": "/d"
}
}
]
}
]
}
},
{
"fullUrl": "https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/guidelines/covid19-intensive-care-treatment/dexamethasone/recommendation-action-intravenous",
"resource": {
"resourceType": "ActivityDefinition",
"id": "DexamethasoneApplicationActionIntravenous",
"meta": {
"profile": [
"https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/StructureDefinition/drug-administration-action"
]
},
"text": {
"status": "extensions",
"div": "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"ActivityDefinition_DexamethasoneApplicationActionIntravenous\"> </a><p class=\"res-header-id\"><b>Generated Narrative: ActivityDefinition DexamethasoneApplicationActionIntravenous</b></p><a name=\"DexamethasoneApplicationActionIntravenous\"> </a><a name=\"hcDexamethasoneApplicationActionIntravenous\"> </a><a name=\"DexamethasoneApplicationActionIntravenous-en-US\"> </a><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\"/><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-drug-administration-action.html\">Drug Administration Action</a></p></div><p><b>knowledgeCapability</b>: computable</p><p><b>knowledgeRepresentationLevel</b>: structured</p><p><b>url</b>: <a href=\"ActivityDefinition-DexamethasoneApplicationActionIntravenous.html\">ActivityDefinition DexamethasoneApplicationActionIntravenous</a></p><p><b>version</b>: 1.0</p><p><b>name</b>: DexamethasoneApplicationActionIntravenous</p><p><b>status</b>: Active</p><p><b>experimental</b>: true</p><p><b>subject</b>: <span title=\"Codes:{http://hl7.org/fhir/fhir-types Patient}\">Patient</span></p><p><b>publisher</b>: CPGonEBMonFHIR</p><p><b>description</b>: </p><div><p>Application of Dexamethasone: 6 mg once per day for 10 days (intravenous route)</p>\n</div><p><b>kind</b>: MedicationRequest</p><p><b>code</b>: <span title=\"Codes:{http://snomed.info/sct 18629005}\">Administration of drug or medicament (procedure)</span></p><p><b>product</b>: <span title=\"Codes:{http://snomed.info/sct 372584003}, {http://fhir.de/CodeSystem/bfarm/atc C05AA09}\">Dexamethasone (substance)</span></p><blockquote><p><b>dosage</b></p><p><b>timing</b>: Count 10 times, Duration 10days , Once per 1 day</p><p><b>route</b>: <span title=\"Codes:{http://snomed.info/sct 47625008}\">Intravenous route</span></p><h3>DoseAndRates</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Dose[x]</b></td><td><b>Rate[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>6 mg<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM codemg = 'mg')</span></td><td>1 /d<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code/d = '/d')</span></td></tr></table></blockquote></div>"
},
"extension": [
{
"url": "http://hl7.org/fhir/uv/cpg/StructureDefinition/cpg-knowledgeCapability",
"valueCode": "computable"
},
{
"url": "http://hl7.org/fhir/uv/cpg/StructureDefinition/cpg-knowledgeRepresentationLevel",
"valueCode": "structured"
}
],
"url": "https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/recommendation-action/dexamethasone-application-intravenous",
"version": "1.0",
"name": "DexamethasoneApplicationActionIntravenous",
"status": "active",
"experimental": true,
"subjectCodeableConcept": {
"coding": [
{
"system": "http://hl7.org/fhir/fhir-types",
"code": "Patient"
}
]
},
"publisher": "CPGonEBMonFHIR",
"description": "Application of Dexamethasone: 6 mg once per day for 10 days (intravenous route)",
"kind": "MedicationRequest",
"code": {
"coding": [
{
"system": "http://snomed.info/sct",
"code": "18629005",
"display": "Administration of drug or medicament (procedure)"
}
]
},
"productCodeableConcept": {
"coding": [
{
"system": "http://snomed.info/sct",
"code": "372584003",
"display": "Dexamethasone (substance)"
},
{
"system": "http://fhir.de/CodeSystem/bfarm/atc",
"code": "C05AA09",
"display": "Dexamethason"
}
]
},
"dosage": [
{
"timing": {
"repeat": {
"count": 10,
"duration": 10,
"durationUnit": "d",
"frequency": 1,
"period": 1,
"periodUnit": "d"
}
},
"route": {
"coding": [
{
"system": "http://snomed.info/sct",
"code": "47625008",
"display": "Intravenous route"
}
]
},
"doseAndRate": [
{
"doseQuantity": {
"value": 6,
"unit": "mg",
"system": "http://unitsofmeasure.org",
"code": "mg"
},
"rateQuantity": {
"value": 1,
"unit": "/d",
"system": "http://unitsofmeasure.org",
"code": "/d"
}
}
]
}
]
}
},
{
"fullUrl": "https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/guidelines/covid19-intensive-care-treatment/dexamethasone/recommendation-action-no-application",
"resource": {
"resourceType": "ActivityDefinition",
"id": "NoDexamethasoneApplication",
"meta": {
"profile": [
"https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/StructureDefinition/drug-administration-action"
]
},
"text": {
"status": "extensions",
"div": "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"ActivityDefinition_NoDexamethasoneApplication\"> </a><p class=\"res-header-id\"><b>Generated Narrative: ActivityDefinition NoDexamethasoneApplication</b></p><a name=\"NoDexamethasoneApplication\"> </a><a name=\"hcNoDexamethasoneApplication\"> </a><a name=\"NoDexamethasoneApplication-en-US\"> </a><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\"/><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-drug-administration-action.html\">Drug Administration Action</a></p></div><p><b>knowledgeCapability</b>: computable</p><p><b>knowledgeRepresentationLevel</b>: structured</p><p><b>url</b>: <a href=\"ActivityDefinition-NoDexamethasoneApplication.html\">ActivityDefinition NoDexamethasoneApplicationActivity</a></p><p><b>version</b>: 1.0</p><p><b>name</b>: NoDexamethasoneApplicationActivity</p><p><b>status</b>: Active</p><p><b>experimental</b>: true</p><p><b>subject</b>: <span title=\"Codes:{http://hl7.org/fhir/fhir-types Patient}\">Patient</span></p><p><b>publisher</b>: CPGonEBMonFHIR</p><p><b>description</b>: </p><div><p>No Application of Dexamethasone</p>\n</div><p><b>kind</b>: MedicationRequest</p><p><b>code</b>: <span title=\"Codes:{http://snomed.info/sct 18629005}\">Administration of drug or medicament (procedure)</span></p><p><b>doNotPerform</b>: true</p><p><b>product</b>: <span title=\"Codes:{http://snomed.info/sct 372584003}, {http://fhir.de/CodeSystem/bfarm/atc C05AA09}\">Dexamethasone (substance)</span></p><blockquote><p><b>dosage</b></p><p><b>route</b>: <span title=\"Codes:{http://snomed.info/sct 26643006}\">Oral route</span></p><h3>DoseAndRates</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Dose[x]</b></td><td><b>Rate[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>6 mg<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM codemg = 'mg')</span></td><td>1 /d<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code/d = '/d')</span></td></tr></table></blockquote></div>"
},
"extension": [
{
"url": "http://hl7.org/fhir/uv/cpg/StructureDefinition/cpg-knowledgeCapability",
"valueCode": "computable"
},
{
"url": "http://hl7.org/fhir/uv/cpg/StructureDefinition/cpg-knowledgeRepresentationLevel",
"valueCode": "structured"
}
],
"url": "https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/recommendation-action/no-dexamethasone-application",
"version": "1.0",
"name": "NoDexamethasoneApplicationActivity",
"status": "active",
"experimental": true,
"subjectCodeableConcept": {
"coding": [
{
"system": "http://hl7.org/fhir/fhir-types",
"code": "Patient"
}
]
},
"publisher": "CPGonEBMonFHIR",
"description": "No Application of Dexamethasone",
"kind": "MedicationRequest",
"code": {
"coding": [
{
"system": "http://snomed.info/sct",
"code": "18629005",
"display": "Administration of drug or medicament (procedure)"
}
]
},
"doNotPerform": true,
"productCodeableConcept": {
"coding": [
{
"system": "http://snomed.info/sct",
"code": "372584003",
"display": "Dexamethasone (substance)"
},
{
"system": "http://fhir.de/CodeSystem/bfarm/atc",
"code": "C05AA09",
"display": "Dexamethason"
}
]
},
"dosage": [
{
"route": {
"coding": [
{
"system": "http://snomed.info/sct",
"code": "26643006",
"display": "Oral route"
}
]
},
"doseAndRate": [
{
"doseQuantity": {
"value": 6,
"unit": "mg",
"system": "http://unitsofmeasure.org",
"code": "mg"
},
"rateQuantity": {
"value": 1,
"unit": "/d",
"system": "http://unitsofmeasure.org",
"code": "/d"
}
}
]
}
]
}
},
{
"fullUrl": "https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/guidelines/covid19-intensive-care-treatment/dexamethasone/recommendation-citation",
"resource": {
"resourceType": "Citation",
"id": "DexamethasoneRecommendationCitation",
"meta": {
"profile": [
"https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/StructureDefinition/recommendation-citation"
]
},
"text": {
"status": "generated",
"div": "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Citation_DexamethasoneRecommendationCitation\"> </a><p class=\"res-header-id\"><b>Generated Narrative: Citation DexamethasoneRecommendationCitation</b></p><a name=\"DexamethasoneRecommendationCitation\"> </a><a name=\"hcDexamethasoneRecommendationCitation\"> </a><a name=\"DexamethasoneRecommendationCitation-en-US\"> </a><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\"/><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-recommendation-citation.html\">Recommendation Citation</a></p></div><p><b>name</b>: DexamethasoneRecommendationCitation</p><p><b>status</b>: Active</p><blockquote><p><b>citedArtifact</b></p><p><b>identifier</b>: <code>https://api.magicapp.org/api/v1/recommendations</code>/98398</p><h3>Versions</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Value</b></td></tr><tr><td style=\"display: none\">*</td><td>v4.0</td></tr></table><p><b>currentState</b>: <span title=\"Codes:{http://hl7.org/fhir/cited-artifact-status-type active}\">Active</span></p><h3>Titles</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Text</b></td></tr><tr><td style=\"display: none\">*</td><td><div><p>Steroide</p>\n</div></td></tr></table><h3>Classifications</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Type</b></td><td><b>Classifier</b></td></tr><tr><td style=\"display: none\">*</td><td><span title=\"Codes:{http://hl7.org/fhir/cited-artifact-classification-type publication-type}\">Publication Type</span></td><td><span title=\"Codes:{https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/CodeSystem/ceosys-code-system guideline-recommendation}\">Clinical practice guideline recommendation</span></td></tr></table></blockquote></div>"
},
"name": "DexamethasoneRecommendationCitation",
"status": "active",
"citedArtifact": {
"identifier": [
{
"system": "https://api.magicapp.org/api/v1/recommendations",
"value": "98398"
}
],
"version": {
"value": "v4.0"
},
"currentState": [
{
"coding": [
{
"system": "http://hl7.org/fhir/cited-artifact-status-type",
"code": "active",
"display": "Active"
}
]
}
],
"title": [
{
"text": "Steroide"
}
],
"classification": [
{
"type": {
"coding": [
{
"system": "http://hl7.org/fhir/cited-artifact-classification-type",
"code": "publication-type",
"display": "Publication Type"
}
]
},
"classifier": [
{
"coding": [
{
"system": "https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/CodeSystem/ceosys-code-system",
"code": "guideline-recommendation",
"display": "Clinical practice guideline recommendation"
}
]
}
]
}
]
}
}
},
{
"fullUrl": "https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/guidelines/covid19-intensive-care-treatment/evidence-variable-ventilated",
"resource": {
"resourceType": "EvidenceVariable",
"id": "PopulationCOVID19Ventilated",
"meta": {
"profile": [
"https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/StructureDefinition/recommendation-eligibility-criteria"
]
},
"text": {
"status": "generated",
"div": "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"EvidenceVariable_PopulationCOVID19Ventilated\"> </a><p class=\"res-header-id\"><b>Generated Narrative: EvidenceVariable PopulationCOVID19Ventilated</b></p><a name=\"PopulationCOVID19Ventilated\"> </a><a name=\"hcPopulationCOVID19Ventilated\"> </a><a name=\"PopulationCOVID19Ventilated-en-US\"> </a><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\"/><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-recommendation-eligibility-criteria.html\">Recommendation Eligibility Criteria</a></p></div><p><b>url</b>: <a href=\"EvidenceVariable-PopulationCOVID19Ventilated.html\">EvidenceVariable Population_COVID19_Ventilated</a></p><p><b>identifier</b>: <code>https://www.ceosys.de</code>/Ventilated</p><p><b>name</b>: Population_COVID19_Ventilated</p><p><b>status</b>: Active</p><p><b>description</b>: </p><div><p>Population for guideline from https://app.magicapp.org/#/guidelines / 5691 with characteristics: COVID-19, Ventilated</p>\n</div><blockquote><p><b>characteristic</b></p><p><b>linkId</b>: covid19</p><h3>DefinitionByTypeAndValues</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Type</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td><span title=\"Codes:{http://snomed.info/sct 404684003}\">Clinical finding (finding)</span></td><td><span title=\"Codes:{http://snomed.info/sct 840539006}\">Disease caused by Severe acute respiratory syndrome coronavirus 2 (disorder)</span></td></tr></table></blockquote><blockquote><p><b>characteristic</b></p><p><b>exclude</b>: false</p><blockquote><p><b>definitionByCombination</b></p><p><b>code</b>: Any of</p><blockquote><p><b>characteristic</b></p><p><b>linkId</b>: oxy-administration-nasal-cannula</p><p><b>exclude</b>: false</p><h3>DefinitionByTypeAndValues</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Type</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td><span title=\"Codes:{http://snomed.info/sct 71388002}\">Procedure (procedure)</span></td><td><span title=\"Codes:{http://snomed.info/sct 371907003}\">Oxygen administration by nasal cannula (procedure)</span></td></tr></table><h3>TimeFromEvents</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Event[x]</b></td><td><b>Quantity</b></td></tr><tr><td style=\"display: none\">*</td><td>covid19</td><td>0 d<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM coded = 'd')</span></td></tr></table></blockquote><blockquote><p><b>characteristic</b></p><p><b>linkId</b>: noninvasive-ventilation</p><p><b>exclude</b>: false</p><h3>DefinitionByTypeAndValues</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Type</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td><span title=\"Codes:{http://snomed.info/sct 71388002}\">Procedure (procedure)</span></td><td><span title=\"Codes:{http://snomed.info/sct 428311008}\">Non-invasive ventilation (regime/therapy)</span></td></tr></table><h3>TimeFromEvents</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Event[x]</b></td><td><b>Quantity</b></td></tr><tr><td style=\"display: none\">*</td><td>covid19</td><td>0 d<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM coded = 'd')</span></td></tr></table></blockquote><blockquote><p><b>characteristic</b></p><p><b>linkId</b>: artificial-respiration</p><p><b>exclude</b>: false</p><h3>DefinitionByTypeAndValues</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Type</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td><span title=\"Codes:{http://snomed.info/sct 71388002}\">Procedure (procedure)</span></td><td><span title=\"Codes:{http://snomed.info/sct 40617009}\">Artificial ventilation (regime/therapy)</span></td></tr></table><h3>TimeFromEvents</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Event[x]</b></td><td><b>Quantity</b></td></tr><tr><td style=\"display: none\">*</td><td>covid19</td><td>0 d<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM coded = 'd')</span></td></tr></table></blockquote></blockquote></blockquote></div>"
},
"url": "https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/population/Population_COVID19_Ventilated",
"identifier": [
{
"system": "https://www.ceosys.de",
"value": "Ventilated"
}
],
"name": "Population_COVID19_Ventilated",
"status": "active",
"description": "Population for guideline from https://app.magicapp.org/#/guidelines / 5691 with characteristics: COVID-19, Ventilated",
"characteristic": [
{
"linkId": "covid19",
"definitionByTypeAndValue": {
"type": {
"coding": [
{
"system": "http://snomed.info/sct",
"code": "404684003",
"display": "Clinical finding (finding)"
}
]
},
"valueCodeableConcept": {
"coding": [
{
"system": "http://snomed.info/sct",
"code": "840539006",
"display": "Disease caused by Severe acute respiratory syndrome coronavirus 2 (disorder)"
}
]
}
}
},
{
"exclude": false,
"definitionByCombination": {
"code": "any-of",
"characteristic": [
{
"linkId": "oxy-administration-nasal-cannula",
"exclude": false,
"definitionByTypeAndValue": {
"type": {
"coding": [
{
"system": "http://snomed.info/sct",
"code": "71388002",
"display": "Procedure (procedure)"
}
]
},
"valueCodeableConcept": {
"coding": [
{
"system": "http://snomed.info/sct",
"code": "371907003",
"display": "Oxygen administration by nasal cannula (procedure)"
}
]
}
},
"timeFromEvent": [
{
"eventId": "covid19",
"quantity": {
"value": 0,
"system": "http://unitsofmeasure.org",
"code": "d"
}
}
]
},
{
"linkId": "noninvasive-ventilation",
"exclude": false,
"definitionByTypeAndValue": {
"type": {
"coding": [
{
"system": "http://snomed.info/sct",
"code": "71388002",
"display": "Procedure (procedure)"
}
]
},
"valueCodeableConcept": {
"coding": [
{
"system": "http://snomed.info/sct",
"code": "428311008",
"display": "Non-invasive ventilation (regime/therapy)"
}
]
}
},
"timeFromEvent": [
{
"eventId": "covid19",
"quantity": {
"value": 0,
"system": "http://unitsofmeasure.org",
"code": "d"
}
}
]
},
{
"linkId": "artificial-respiration",
"exclude": false,
"definitionByTypeAndValue": {
"type": {
"coding": [
{
"system": "http://snomed.info/sct",
"code": "71388002",
"display": "Procedure (procedure)"
}
]
},
"valueCodeableConcept": {
"coding": [
{
"system": "http://snomed.info/sct",
"code": "40617009",
"display": "Artificial ventilation (regime/therapy)"
}
]
}
},
"timeFromEvent": [
{
"eventId": "covid19",
"quantity": {
"value": 0,
"system": "http://unitsofmeasure.org",
"code": "d"
}
}
]
}
]
}
}
]
}
},
{
"fullUrl": "https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/guidelines/covid19-intensive-care-treatment/evidence-variable-non-ventilated",
"resource": {
"resourceType": "EvidenceVariable",
"id": "PopulationCOVID19NonVentilated",
"meta": {
"profile": [
"https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/StructureDefinition/recommendation-eligibility-criteria"
]
},
"text": {
"status": "generated",
"div": "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"EvidenceVariable_PopulationCOVID19NonVentilated\"> </a><p class=\"res-header-id\"><b>Generated Narrative: EvidenceVariable PopulationCOVID19NonVentilated</b></p><a name=\"PopulationCOVID19NonVentilated\"> </a><a name=\"hcPopulationCOVID19NonVentilated\"> </a><a name=\"PopulationCOVID19NonVentilated-en-US\"> </a><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\"/><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-recommendation-eligibility-criteria.html\">Recommendation Eligibility Criteria</a></p></div><p><b>url</b>: <a href=\"EvidenceVariable-PopulationCOVID19NonVentilated.html\">EvidenceVariable Population_COVID19_NonVentilated</a></p><p><b>identifier</b>: <code>https://www.ceosys.de</code>/NonVentilated</p><p><b>name</b>: Population_COVID19_NonVentilated</p><p><b>status</b>: Active</p><p><b>description</b>: </p><div><p>Population for guideline from https://app.magicapp.org/#/guidelines / 5691 with characteristics: COVID-19, not ventilated</p>\n</div><blockquote><p><b>characteristic</b></p><p><b>linkId</b>: covid19</p><p><b>exclude</b>: false</p><h3>DefinitionByTypeAndValues</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Type</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td><span title=\"Codes:{http://snomed.info/sct 404684003}\">Clinical finding (finding)</span></td><td><span title=\"Codes:{http://snomed.info/sct 840539006}\">Disease caused by Severe acute respiratory syndrome coronavirus 2 (disorder)</span></td></tr></table></blockquote><blockquote><p><b>characteristic</b></p><p><b>exclude</b>: true</p><blockquote><p><b>definitionByCombination</b></p><p><b>code</b>: Any of</p><blockquote><p><b>characteristic</b></p><p><b>linkId</b>: oxy-administration-nasal-cannula</p><p><b>exclude</b>: false</p><h3>DefinitionByTypeAndValues</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Type</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td><span title=\"Codes:{http://snomed.info/sct 71388002}\">Procedure (procedure)</span></td><td><span title=\"Codes:{http://snomed.info/sct 371907003}\">Oxygen administration by nasal cannula (procedure)</span></td></tr></table><h3>TimeFromEvents</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Event[x]</b></td><td><b>Quantity</b></td></tr><tr><td style=\"display: none\">*</td><td>covid19</td><td>0 d<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM coded = 'd')</span></td></tr></table></blockquote><blockquote><p><b>characteristic</b></p><p><b>linkId</b>: noninvasive-ventilation</p><p><b>exclude</b>: false</p><h3>DefinitionByTypeAndValues</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Type</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td><span title=\"Codes:{http://snomed.info/sct 71388002}\">Procedure (procedure)</span></td><td><span title=\"Codes:{http://snomed.info/sct 428311008}\">Non-invasive ventilation (regime/therapy)</span></td></tr></table><h3>TimeFromEvents</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Event[x]</b></td><td><b>Quantity</b></td></tr><tr><td style=\"display: none\">*</td><td>covid19</td><td>0 d<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM coded = 'd')</span></td></tr></table></blockquote><blockquote><p><b>characteristic</b></p><p><b>linkId</b>: artificial-respiration</p><p><b>exclude</b>: false</p><h3>DefinitionByTypeAndValues</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Type</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td><span title=\"Codes:{http://snomed.info/sct 71388002}\">Procedure (procedure)</span></td><td><span title=\"Codes:{http://snomed.info/sct 40617009}\">Artificial ventilation (regime/therapy)</span></td></tr></table><h3>TimeFromEvents</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Event[x]</b></td><td><b>Quantity</b></td></tr><tr><td style=\"display: none\">*</td><td>covid19</td><td>0 d<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM coded = 'd')</span></td></tr></table></blockquote></blockquote></blockquote></div>"
},
"url": "https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/population/Population_COVID19_NonVentilated",
"identifier": [
{
"system": "https://www.ceosys.de",
"value": "NonVentilated"
}
],
"name": "Population_COVID19_NonVentilated",
"status": "active",
"description": "Population for guideline from https://app.magicapp.org/#/guidelines / 5691 with characteristics: COVID-19, not ventilated",
"characteristic": [
{
"linkId": "covid19",
"exclude": false,
"definitionByTypeAndValue": {
"type": {
"coding": [
{
"system": "http://snomed.info/sct",
"code": "404684003",
"display": "Clinical finding (finding)"
}
]
},
"valueCodeableConcept": {
"coding": [
{
"system": "http://snomed.info/sct",
"code": "840539006",
"display": "Disease caused by Severe acute respiratory syndrome coronavirus 2 (disorder)"
}
]
}
}
},
{
"exclude": true,
"definitionByCombination": {
"code": "any-of",
"characteristic": [
{
"linkId": "oxy-administration-nasal-cannula",
"exclude": false,
"definitionByTypeAndValue": {
"type": {
"coding": [
{
"system": "http://snomed.info/sct",
"code": "71388002",
"display": "Procedure (procedure)"
}
]
},
"valueCodeableConcept": {
"coding": [
{
"system": "http://snomed.info/sct",
"code": "371907003",
"display": "Oxygen administration by nasal cannula (procedure)"
}
]
}
},
"timeFromEvent": [
{
"eventId": "covid19",
"quantity": {
"value": 0,
"system": "http://unitsofmeasure.org",
"code": "d"
}
}
]
},
{
"linkId": "noninvasive-ventilation",
"exclude": false,
"definitionByTypeAndValue": {
"type": {
"coding": [
{
"system": "http://snomed.info/sct",
"code": "71388002",
"display": "Procedure (procedure)"
}
]
},
"valueCodeableConcept": {
"coding": [
{
"system": "http://snomed.info/sct",
"code": "428311008",
"display": "Non-invasive ventilation (regime/therapy)"
}
]
}
},
"timeFromEvent": [
{
"eventId": "covid19",
"quantity": {
"value": 0,
"system": "http://unitsofmeasure.org",
"code": "d"
}
}
]
},
{
"linkId": "artificial-respiration",
"exclude": false,
"definitionByTypeAndValue": {
"type": {
"coding": [
{
"system": "http://snomed.info/sct",
"code": "71388002",
"display": "Procedure (procedure)"
}
]
},
"valueCodeableConcept": {
"coding": [
{
"system": "http://snomed.info/sct",
"code": "40617009",
"display": "Artificial ventilation (regime/therapy)"
}
]
}
},
"timeFromEvent": [
{
"eventId": "covid19",
"quantity": {
"value": 0,
"system": "http://unitsofmeasure.org",
"code": "d"
}
}
]
}
]
}
}
]
}
},
{
"fullUrl": "https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/guidelines/covid19-intensive-care-treatment/dexamethasone/rating-outcome-mortality",
"resource": {
"resourceType": "ArtifactAssessment",
"id": "DexamethasoneRatingOutcomeMortality",
"meta": {
"profile": [
"https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/StructureDefinition/certainty-of-evidence-rating"
]
},
"text": {
"status": "extensions",
"div": "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"ArtifactAssessment_DexamethasoneRatingOutcomeMortality\"> </a><p class=\"res-header-id\"><b>Generated Narrative: ArtifactAssessment DexamethasoneRatingOutcomeMortality</b></p><a name=\"DexamethasoneRatingOutcomeMortality\"> </a><a name=\"hcDexamethasoneRatingOutcomeMortality\"> </a><a name=\"DexamethasoneRatingOutcomeMortality-en-US\"> </a><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\"/><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-certainty-of-evidence-rating.html\">Certainty of Evidence Rating</a></p></div><p><b>ArtifactAssessment Version</b>: v4.0</p><p><b>ArtifactAssessment Publication Status</b>: active</p><p><b>date</b>: 2020-01-03</p><p><b>artifact</b>: <a href=\"Evidence-DexamethasoneOutcomeMortality.html\">Evidence ExampleOutcomeEvidence</a></p><blockquote><p><b>content</b></p><p><b>informationType</b>: Rating</p><p><b>type</b>: <span title=\"Codes:{http://hl7.org/fhir/certainty-type Overall}\">Overall certainty</span></p><p><b>classifier</b>: <span title=\"Codes:{http://hl7.org/fhir/certainty-rating moderate}\">Moderate quality</span></p></blockquote><blockquote><p><b>content</b></p><p><b>informationType</b>: Rating</p><p><b>type</b>: <span title=\"Codes:{https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/CodeSystem/ceosys-code-system clinical-importance}\">Clinical Importance</span></p><p><b>classifier</b>: <span title=\"Codes:{https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/CodeSystem/cs-clinical-importance 9}\">Critical</span></p></blockquote><blockquote><p><b>content</b></p><p><b>informationType</b>: Rating</p><p><b>type</b>: <span title=\"Codes:{http://hl7.org/fhir/certainty-type RiskOfBias}\">Risk of bias</span></p><p><b>classifier</b>: <span title=\"Codes:{http://hl7.org/fhir/certainty-rating serious-concern}\">serious concern</span></p></blockquote><blockquote><p><b>content</b></p><p><b>informationType</b>: Rating</p><p><b>type</b>: <span title=\"Codes:{http://hl7.org/fhir/certainty-type Inconsistency}\">Inconsistency</span></p><p><b>classifier</b>: <span title=\"Codes:{http://hl7.org/fhir/certainty-rating no-concern}\">no serious concern</span></p></blockquote><blockquote><p><b>content</b></p><p><b>informationType</b>: Rating</p><p><b>type</b>: <span title=\"Codes:{http://hl7.org/fhir/certainty-type Indirectness}\">Indirectness</span></p><p><b>classifier</b>: <span title=\"Codes:{http://hl7.org/fhir/certainty-rating no-concern}\">no serious concern</span></p></blockquote><blockquote><p><b>content</b></p><p><b>informationType</b>: Rating</p><p><b>type</b>: <span title=\"Codes:{http://hl7.org/fhir/certainty-type Imprecision}\">Imprecision</span></p><p><b>classifier</b>: <span title=\"Codes:{http://hl7.org/fhir/certainty-rating no-concern}\">no serious concern</span></p></blockquote><blockquote><p><b>content</b></p><p><b>informationType</b>: Rating</p><p><b>type</b>: <span title=\"Codes:{http://hl7.org/fhir/certainty-type PublicationBias}\">Publication bias</span></p><p><b>classifier</b>: <span title=\"Codes:{http://hl7.org/fhir/certainty-rating no-concern}\">no serious concern</span></p></blockquote></div>"
},
"extension": [
{
"url": "https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/StructureDefinition/ceosys-extension-artifact-assessment-version",
"valueString": "v4.0"
},
{
"url": "https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/StructureDefinition/ceosys-extension-artifact-assessment-publication-status",
"valueCode": "active"
}
],
"date": "2020-01-03",
"artifactReference": {
"reference": "Evidence/DexamethasoneOutcomeMortality"
},
"content": [
{
"informationType": "rating",
"type": {
"coding": [
{
"system": "http://hl7.org/fhir/certainty-type",
"code": "Overall",
"display": "Overall certainty"
}
]
},
"classifier": [
{
"coding": [
{
"system": "http://hl7.org/fhir/certainty-rating",
"code": "moderate",
"display": "Moderate quality"
}
]
}
]
},
{
"informationType": "rating",
"type": {
"coding": [
{
"system": "https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/CodeSystem/ceosys-code-system",
"code": "clinical-importance",
"display": "Clinical Importance"
}
]
},
"classifier": [
{
"coding": [
{
"system": "https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/CodeSystem/cs-clinical-importance",
"code": "9",
"display": "Critical"
}
]
}
]
},
{
"informationType": "rating",
"type": {
"coding": [
{
"system": "http://hl7.org/fhir/certainty-type",
"code": "RiskOfBias",
"display": "Risk of bias"
}
]
},
"classifier": [
{
"coding": [
{
"system": "http://hl7.org/fhir/certainty-rating",
"code": "serious-concern",
"display": "serious concern"
}
]
}
]
},
{
"informationType": "rating",
"type": {
"coding": [
{
"system": "http://hl7.org/fhir/certainty-type",
"code": "Inconsistency",
"display": "Inconsistency"
}
]
},
"classifier": [
{
"coding": [
{
"system": "http://hl7.org/fhir/certainty-rating",
"code": "no-concern",
"display": "no serious concern"
}
]
}
]
},
{
"informationType": "rating",
"type": {
"coding": [
{
"system": "http://hl7.org/fhir/certainty-type",
"code": "Indirectness",
"display": "Indirectness"
}
]
},
"classifier": [
{
"coding": [
{
"system": "http://hl7.org/fhir/certainty-rating",
"code": "no-concern",
"display": "no serious concern"
}
]
}
]
},
{
"informationType": "rating",
"type": {
"coding": [
{
"system": "http://hl7.org/fhir/certainty-type",
"code": "Imprecision",
"display": "Imprecision"
}
]
},
"classifier": [
{
"coding": [
{
"system": "http://hl7.org/fhir/certainty-rating",
"code": "no-concern",
"display": "no serious concern"
}
]
}
]
},
{
"informationType": "rating",
"type": {
"coding": [
{
"system": "http://hl7.org/fhir/certainty-type",
"code": "PublicationBias",
"display": "Publication bias"
}
]
},
"classifier": [
{
"coding": [
{
"system": "http://hl7.org/fhir/certainty-rating",
"code": "no-concern",
"display": "no serious concern"
}
]
}
]
}
]
}
},
{
"fullUrl": "https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/guidelines/covid19-intensive-care-treatment/dexamethasone/outcome-mortality",
"resource": {
"resourceType": "Evidence",
"id": "DexamethasoneOutcomeMortality",
"meta": {
"profile": [
"https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/StructureDefinition/outcome-evidence-synthesis"
]
},
"text": {
"status": "generated",
"div": "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Evidence_DexamethasoneOutcomeMortality\"> </a><p class=\"res-header-id\"><b>Generated Narrative: Evidence DexamethasoneOutcomeMortality</b></p><a name=\"DexamethasoneOutcomeMortality\"> </a><a name=\"hcDexamethasoneOutcomeMortality\"> </a><a name=\"DexamethasoneOutcomeMortality-en-US\"> </a><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\"/><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-outcome-evidence-synthesis.html\">Outcome Evidence Synthesis</a></p></div><p><b>name</b>: ExampleOutcomeEvidence</p><p><b>status</b>: Active</p><h3>RelatedArtifacts</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Type</b></td><td><b>ResourceReference</b></td></tr><tr><td style=\"display: none\">*</td><td>Citation</td><td><a href=\"Citation-SystemicCorticosteroidsForTheTreatmentOfCOVID19.html\">Citation SystemicCorticosteroidsForTheTreatmentOfCOVID19</a></td></tr></table><blockquote><p><b>variableDefinition</b></p><p><b>variableRole</b>: <span title=\"Codes:{http://terminology.hl7.org/CodeSystem/variable-role population}\">population</span></p><p><b>observed</b>: <a href=\"Group-StudyCohortCorticosteroidsCOVID19.html\">Group StudyCohortCriteriaSystemicCorticosteroidsCOVID19</a></p><p><b>intended</b>: <a href=\"EvidenceVariable-StudyEligibilityCriteriaSystemicCorticosteroidsCOVID19.html\">EvidenceVariable StudyEligibilityCriteriaSystemicCorticosteroidsCOVID19</a></p></blockquote><blockquote><p><b>variableDefinition</b></p><p><b>variableRole</b>: <span title=\"Codes:{http://terminology.hl7.org/CodeSystem/variable-role measuredVariable}\">measured variable</span></p><p><b>observed</b>: <a href=\"EvidenceVariable-OutcomeAllCauseMortality.html\">EvidenceVariable AllCauseMortality</a></p></blockquote><p><b>synthesisType</b>: <span title=\"Codes:{http://terminology.hl7.org/CodeSystem/synthesis-type NotApplicable}\">not applicable</span></p><blockquote><p><b>statistic</b></p><p><b>description</b>: </p><div><p>Relative effect of intervention vs. comparator</p>\n</div><p><b>statisticType</b>: <span title=\"Codes:{http://terminology.hl7.org/CodeSystem/statistic-type C93152}\">Relative Risk</span></p><p><b>quantity</b>: 0.89</p><h3>SampleSizes</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>NumberOfStudies</b></td><td><b>NumberOfParticipants</b></td></tr><tr><td style=\"display: none\">*</td><td>9</td><td>7930</td></tr></table><h3>AttributeEstimates</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Type</b></td><td><b>Level</b></td><td><b>Range</b></td></tr><tr><td style=\"display: none\">*</td><td><span title=\"Codes:{http://terminology.hl7.org/CodeSystem/attribute-estimate-type C53324}\">Confidence interval</span></td><td>0.95</td><td>0.8-1</td></tr></table></blockquote><blockquote><p><b>statistic</b></p><p><b>description</b>: </p><div><p>Baseline risk/result in the comparison group</p>\n</div><p><b>statisticType</b>: <span title=\"Codes:{http://terminology.hl7.org/CodeSystem/statistic-type C16726}\">Incidence</span></p><p><b>quantity</b>: 245 1/1000<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code1/1000 = '1/1000')</span></p></blockquote></div>"
},
"name": "ExampleOutcomeEvidence",
"status": "active",
"relatedArtifact": [
{
"type": "citation",
"resourceReference": {
"reference": "Citation/SystemicCorticosteroidsForTheTreatmentOfCOVID19"
}
}
],
"variableDefinition": [
{
"variableRole": {
"coding": [
{
"system": "http://terminology.hl7.org/CodeSystem/variable-role",
"code": "population"
}
]
},
"observed": {
"reference": "Group/StudyCohortCorticosteroidsCOVID19"
},
"intended": {
"reference": "EvidenceVariable/StudyEligibilityCriteriaSystemicCorticosteroidsCOVID19"
}
},
{
"variableRole": {
"coding": [
{
"system": "http://terminology.hl7.org/CodeSystem/variable-role",
"code": "measuredVariable"
}
]
},
"observed": {
"reference": "EvidenceVariable/OutcomeAllCauseMortality"
}
}
],
"synthesisType": {
"coding": [
{
"system": "http://terminology.hl7.org/CodeSystem/synthesis-type",
"code": "NotApplicable"
}
]
},
"statistic": [
{
"description": "Relative effect of intervention vs. comparator",
"statisticType": {
"coding": [
{
"system": "http://terminology.hl7.org/CodeSystem/statistic-type",
"code": "C93152",
"display": "Relative Risk"
}
]
},
"quantity": {
"value": 0.89
},
"sampleSize": {
"numberOfStudies": 9,
"numberOfParticipants": 7930
},
"attributeEstimate": [
{
"type": {
"coding": [
{
"system": "http://terminology.hl7.org/CodeSystem/attribute-estimate-type",
"code": "C53324",
"display": "Confidence interval"
}
]
},
"level": 0.95,
"range": {
"low": {
"value": 0.8
},
"high": {
"value": 1
}
}
}
]
},
{
"description": "Baseline risk/result in the comparison group",
"statisticType": {
"coding": [
{
"system": "http://terminology.hl7.org/CodeSystem/statistic-type",
"code": "C16726",
"display": "Incidence"
}
]
},
"quantity": {
"value": 245,
"system": "http://unitsofmeasure.org",
"code": "1/1000"
}
}
]
}
},
{
"fullUrl": "https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/guidelines/covid19-intensive-care-treatment/dexamethasone/study-eligibility-criteria",
"resource": {
"resourceType": "EvidenceVariable",
"id": "StudyEligibilityCriteriaSystemicCorticosteroidsCOVID19",
"meta": {
"profile": [
"https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/StructureDefinition/study-eligibility-criteria"
]
},
"text": {
"status": "generated",
"div": "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"EvidenceVariable_StudyEligibilityCriteriaSystemicCorticosteroidsCOVID19\"> </a><p class=\"res-header-id\"><b>Generated Narrative: EvidenceVariable StudyEligibilityCriteriaSystemicCorticosteroidsCOVID19</b></p><a name=\"StudyEligibilityCriteriaSystemicCorticosteroidsCOVID19\"> </a><a name=\"hcStudyEligibilityCriteriaSystemicCorticosteroidsCOVID19\"> </a><a name=\"StudyEligibilityCriteriaSystemicCorticosteroidsCOVID19-en-US\"> </a><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\"/><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-study-eligibility-criteria.html\">Study Eligibility Criteria</a></p></div><p><b>name</b>: StudyEligibilityCriteriaSystemicCorticosteroidsCOVID19</p><p><b>status</b>: Active</p><blockquote><p><b>characteristic</b></p><h3>DefinitionByTypeAndValues</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Type</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td><span title=\"Codes:{http://snomed.info/sct 404684003}\">Clinical finding (finding)</span></td><td><span title=\"Codes:{http://snomed.info/sct 840539006}\">Disease caused by Severe acute respiratory syndrome coronavirus 2 (disorder)</span></td></tr></table></blockquote></div>"
},
"name": "StudyEligibilityCriteriaSystemicCorticosteroidsCOVID19",
"status": "active",
"characteristic": [
{
"definitionByTypeAndValue": {
"type": {
"coding": [
{
"system": "http://snomed.info/sct",
"code": "404684003",
"display": "Clinical finding (finding)"
}
]
},
"valueCodeableConcept": {
"coding": [
{
"system": "http://snomed.info/sct",
"code": "840539006",
"display": "Disease caused by Severe acute respiratory syndrome coronavirus 2 (disorder)"
}
]
}
}
}
]
}
},
{
"fullUrl": "https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/guidelines/covid19-intensive-care-treatment/outcome-all-cause-mortality",
"resource": {
"resourceType": "EvidenceVariable",
"id": "OutcomeAllCauseMortality",
"meta": {
"profile": [
"https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/StructureDefinition/outcome-definition"
]
},
"text": {
"status": "generated",
"div": "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"EvidenceVariable_OutcomeAllCauseMortality\"> </a><p class=\"res-header-id\"><b>Generated Narrative: EvidenceVariable OutcomeAllCauseMortality</b></p><a name=\"OutcomeAllCauseMortality\"> </a><a name=\"hcOutcomeAllCauseMortality\"> </a><a name=\"OutcomeAllCauseMortality-en-US\"> </a><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\"/><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-outcome-definition.html\">Outcome Definition</a></p></div><p><b>name</b>: AllCauseMortality</p><p><b>status</b>: Active</p><h3>Characteristics</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Exclude</b></td><td><b>DefinitionCodeableConcept</b></td></tr><tr><td style=\"display: none\">*</td><td>false</td><td><span title=\"Codes:{http://snomed.info/sct 409651001}\">Mortality rate (observable entity)</span></td></tr></table><p><b>handling</b>: dichotomous variable</p></div>"
},
"name": "AllCauseMortality",
"status": "active",
"characteristic": [
{
"exclude": false,
"definitionCodeableConcept": {
"coding": [
{
"system": "http://snomed.info/sct",
"code": "409651001",
"display": "Mortality rate (observable entity)"
}
]
}
}
],
"handling": "dichotomous"
}
},
{
"fullUrl": "https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/guidelines/covid19-intensive-care-treatment/dexamethasone/recommendation-justification",
"resource": {
"resourceType": "ArtifactAssessment",
"id": "DexamethasoneRecommendationJustification",
"meta": {
"profile": [
"https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/StructureDefinition/recommendation-justification"
]
},
"text": {
"status": "extensions",
"div": "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"ArtifactAssessment_DexamethasoneRecommendationJustification\"> </a><p class=\"res-header-id\"><b>Generated Narrative: ArtifactAssessment DexamethasoneRecommendationJustification</b></p><a name=\"DexamethasoneRecommendationJustification\"> </a><a name=\"hcDexamethasoneRecommendationJustification\"> </a><a name=\"DexamethasoneRecommendationJustification-en-US\"> </a><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\"/><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-recommendation-justification.html\">Recommendation Justification</a></p></div><p><b>ArtifactAssessment Version</b>: v4.0</p><p><b>ArtifactAssessment Publication Status</b>: active</p><p><b>date</b>: 2020-01-03</p><p><b>artifact</b>: <a href=\"PlanDefinition-COVID19VentilatedPatientsDexamethasoneApplicationPlan.html\">PlanDefinition Dexamethasone Application in ventilated COVID-19 patients</a></p><blockquote><p><b>content</b></p><p><b>informationType</b>: Rating</p><p><b>type</b>: <span title=\"Codes:{https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/CodeSystem/ceosys-code-system strength}\">Strength of recommendation</span></p><p><b>classifier</b>: <span title=\"Codes:{https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/CodeSystem/ceosys-cs-recommendation-strength strong-for}\">Strong for an intervention</span></p></blockquote><blockquote><p><b>content</b></p><p><b>informationType</b>: Rating</p><p><b>type</b>: <span title=\"Codes:{https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/CodeSystem/ceosys-code-system consensus}\">Consensus</span></p><p><b>classifier</b>: <span title=\"Codes:{http://terminology.hl7.org/CodeSystem/recommendation-strength strong}\">Strong</span></p></blockquote><blockquote><p><b>content</b></p><p><b>informationType</b>: Rating</p><p><b>type</b>: <span title=\"Codes:{https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/CodeSystem/cs-evidence-to-decision-certainty-type preference-and-values}\">Preference and values</span></p><p><b>classifier</b>: <span title=\"Codes:{https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/CodeSystem/cs-evidence-to-decision-certainty-rating factor-not-considered}\">Factor not considered</span></p></blockquote><blockquote><p><b>content</b></p><p><b>informationType</b>: Rating</p><p><b>type</b>: <span title=\"Codes:{https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/CodeSystem/cs-evidence-to-decision-certainty-type resources}\">Resources</span></p><p><b>classifier</b>: <span title=\"Codes:{https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/CodeSystem/cs-evidence-to-decision-certainty-rating no-important-issues}\">No important issues</span></p></blockquote><blockquote><p><b>content</b></p><p><b>informationType</b>: Rating</p><p><b>type</b>: <span title=\"Codes:{https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/CodeSystem/cs-evidence-to-decision-certainty-type acceptability}\">Acceptability</span></p><p><b>classifier</b>: <span title=\"Codes:{https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/CodeSystem/cs-evidence-to-decision-certainty-rating factor-not-considered}\">Factor not considered</span></p></blockquote><blockquote><p><b>content</b></p><p><b>informationType</b>: Rating</p><p><b>type</b>: <span title=\"Codes:{https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/CodeSystem/cs-evidence-to-decision-certainty-type feasibility}\">Feasibility</span></p><p><b>classifier</b>: <span title=\"Codes:{https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/CodeSystem/cs-evidence-to-decision-certainty-rating factor-not-considered}\">Factor not considered</span></p></blockquote><blockquote><p><b>content</b></p><p><b>informationType</b>: Container</p><p><b>type</b>: <span title=\"Codes:{https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/CodeSystem/ceosys-code-system certainty-of-evidence-rating}\">Certainty of evidence rating</span></p><h3>RelatedArtifacts</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Type</b></td><td><b>Classifier</b></td><td><b>ResourceReference</b></td></tr><tr><td style=\"display: none\">*</td><td>Justification</td><td><span title=\"Codes:{https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/CodeSystem/ceosys-code-system certainty-of-evidence-rating}\">Certainty of evidence rating</span></td><td><a href=\"ArtifactAssessment-DexamethasoneRatingOutcomeMortality.html\">ArtifactAssessment: extension = v4.0,active; date = 2020-01-03; artifact[x] = ->Evidence ExampleOutcomeEvidence</a></td></tr></table></blockquote></div>"
},
"extension": [
{
"url": "https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/StructureDefinition/ceosys-extension-artifact-assessment-version",
"valueString": "v4.0"
},
{
"url": "https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/StructureDefinition/ceosys-extension-artifact-assessment-publication-status",
"valueCode": "active"
}
],
"date": "2020-01-03",
"artifactReference": {
"reference": "PlanDefinition/COVID19VentilatedPatientsDexamethasoneApplicationPlan"
},
"content": [
{
"informationType": "rating",
"type": {
"coding": [
{
"system": "https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/CodeSystem/ceosys-code-system",
"code": "strength",
"display": "Strength of recommendation"
}
]
},
"classifier": [
{
"coding": [
{
"system": "https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/CodeSystem/ceosys-cs-recommendation-strength",
"code": "strong-for"
}
]
}
]
},
{
"informationType": "rating",
"type": {
"coding": [
{
"system": "https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/CodeSystem/ceosys-code-system",
"code": "consensus",
"display": "Consensus"
}
]
},
"classifier": [
{
"coding": [
{
"system": "http://terminology.hl7.org/CodeSystem/recommendation-strength",
"code": "strong",
"display": "Strong"
}
]
}
]
},
{
"informationType": "rating",
"type": {
"coding": [
{
"system": "https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/CodeSystem/cs-evidence-to-decision-certainty-type",
"code": "preference-and-values",
"display": "Preference and values"
}
]
},
"classifier": [
{
"coding": [
{
"system": "https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/CodeSystem/cs-evidence-to-decision-certainty-rating",
"code": "factor-not-considered",
"display": "Factor not considered"
}
]
}
]
},
{
"informationType": "rating",
"type": {
"coding": [
{
"system": "https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/CodeSystem/cs-evidence-to-decision-certainty-type",
"code": "resources",
"display": "Resources"
}
]
},
"classifier": [
{
"coding": [
{
"system": "https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/CodeSystem/cs-evidence-to-decision-certainty-rating",
"code": "no-important-issues",
"display": "No important issues"
}
]
}
]
},
{
"informationType": "rating",
"type": {
"coding": [
{
"system": "https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/CodeSystem/cs-evidence-to-decision-certainty-type",
"code": "acceptability",
"display": "Acceptability"
}
]
},
"classifier": [
{
"coding": [
{
"system": "https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/CodeSystem/cs-evidence-to-decision-certainty-rating",
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