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Packagede.medizininformatikinitiative.kerndatensatz.seltene
Resource TypeBundle
Idvalidation-oo.json
FHIR VersionR4

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Narrative

No narrative content found in resource


Source1

{
  "resourceType": "Bundle",
  "type": "collection",
  "timestamp": "2026-09-14T22:08:58.012+00:00",
  "entry": [
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/OperationOutcome/ImplementationGuide-mii-ig-seltene",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ImplementationGuide-mii-ig-seltene",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 3785
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/ImplementationGuide|4.0.1"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene'"
            },
            "expression": [
              "ImplementationGuide/mii-ig-seltene: ImplementationGuide.extension[4].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 7482
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/ImplementationGuide|4.0.1"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "ImplementationGuide/mii-ig-seltene: ImplementationGuide.jurisdiction[0].coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 7724
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TYPE_SPECIFIC_CHECKS_DT_CANONICAL_RESOLVE"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/ImplementationGuide|4.0.1"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "A definition could not be found for Canonical URL 'http://fhir.org/packages/de.basisprofil.r4/ImplementationGuide/de.basisprofil.r4'"
            },
            "expression": [
              "ImplementationGuide/mii-ig-seltene: ImplementationGuide.dependsOn[0].uri"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 7775
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "IG_DEPENDENCY_INVALID_URL"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The canonical URL http://fhir.org/packages/de.basisprofil.r4/ImplementationGuide/de.basisprofil.r4 doesn't point to an actual ImplementationGuide resource"
            },
            "expression": [
              "ImplementationGuide/mii-ig-seltene: ImplementationGuide.dependsOn[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 9379
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "IG_DEPENDENCY_VERSION_WARNING_OLD"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The ImplementationGuide uses package hl7.terminology.r4#7.1.0 released on 2026-03-08, but the most recent appropriate version is 7.3.0. This reference is getting old and the more recent version should be considered"
            },
            "expression": [
              "ImplementationGuide/mii-ig-seltene: ImplementationGuide.dependsOn[7]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 9554
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "IG_DEPENDENCY_VERSION_WARNING_OLD"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The ImplementationGuide uses package hl7.fhir.uv.extensions.r4#5.2.0 released on 2025-02-10, but the most recent appropriate version is 5.3.0. This reference is getting old and the more recent version should be considered"
            },
            "expression": [
              "ImplementationGuide/mii-ig-seltene: ImplementationGuide.dependsOn[8]"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/OperationOutcome/Bundle-mii-exa-seltene-bundle-marfan-complete",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Bundle-mii-exa-seltene-bundle-marfan-complete",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 14
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 88
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/Patient|4.0.1"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/sid/patient-id'"
            },
            "expression": [
              "Bundle/mii-exa-seltene-bundle-marfan-complete: Bundle.entry[0].resource/*Patient/mii-exa-seltene-patient-marfan-001*/.identifier[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "BUNDLE_BUNDLE_POSSIBLE_MATCH_WRONG_FU"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/Condition|4.0.1"
              }
            ],
            "severity": "warning",
            "code": "required",
            "details": {
              "text": "Entry 0 matches the reference Patient/mii-exa-seltene-patient-marfan-001 by type and id but its fullUrl urn:uuid:546740dd-771d-41e4-a2a5-e8d6a2b5c505 does not match the full target URL urn:uuid:mii-exa-seltene-patient-marfan-001 by Bundle resolution rules"
            },
            "expression": [
              "Bundle/mii-exa-seltene-bundle-marfan-complete: Bundle.entry[1].resource/*Condition/mii-exa-seltene-condition-marfan-suspected*/.subject"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 114
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/Condition|4.0.1"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'http://omim.org' version '2024' could not be found, so the code cannot be validated. No versions of this code system are known"
            },
            "expression": [
              "Bundle/mii-exa-seltene-bundle-marfan-complete: Bundle.entry[2].resource/*Condition/mii-exa-seltene-condition-marfan-clinical*/.code.coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 114
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/Condition|4.0.1"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'http://snomed.info/sct' version 'null' could not be found, so the code cannot be validated. Valid versions: [http://snomed.info/sct/900000000000207008/version/20230731, http://snomed.info/sct/900000000000207008/version/20240101, http://snomed.info/sct/900000000000207008/version/20240701, http://snomed.info/sct/11000274103/version/20241115, http://snomed.info/sct/900000000000207008/version/20250101, http://snomed.info/sct/900000000000207008/version/20250701, http://snomed.info/sct/11000274103/version/20231115, http://snomed.info/sct/11010000107/version/20250921, http://snomed.info/sct/11000274103/version/20250515, http://snomed.info/sct/11000274103/version/20240515, http://snomed.info/sct/11000274103/version/20251115, http://snomed.info/sct/900000000000207008/version/20260101, http://snomed.info/sct/900000000000207008/version/20260701, http://snomed.info/sct/11000274103/version/20260515]"
            },
            "expression": [
              "Bundle/mii-exa-seltene-bundle-marfan-complete: Bundle.entry[2].resource/*Condition/mii-exa-seltene-condition-marfan-clinical*/.code.coding[1].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 114
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/Condition|4.0.1"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'http://www.orpha.net' version 'null' could not be found, so the code cannot be validated. Valid versions: [2023, 2024, 2025]"
            },
            "expression": [
              "Bundle/mii-exa-seltene-bundle-marfan-complete: Bundle.entry[2].resource/*Condition/mii-exa-seltene-condition-marfan-clinical*/.code.coding[2].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "BUNDLE_BUNDLE_POSSIBLE_MATCH_WRONG_FU"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/Condition|4.0.1"
              }
            ],
            "severity": "warning",
            "code": "required",
            "details": {
              "text": "Entry 0 matches the reference Patient/mii-exa-seltene-patient-marfan-001 by type and id but its fullUrl urn:uuid:546740dd-771d-41e4-a2a5-e8d6a2b5c505 does not match the full target URL urn:uuid:mii-exa-seltene-patient-marfan-001 by Bundle resolution rules"
            },
            "expression": [
              "Bundle/mii-exa-seltene-bundle-marfan-complete: Bundle.entry[2].resource/*Condition/mii-exa-seltene-condition-marfan-clinical*/.subject"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "BUNDLE_BUNDLE_POSSIBLE_MATCH_WRONG_FU"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/Condition|4.0.1"
              }
            ],
            "severity": "warning",
            "code": "required",
            "details": {
              "text": "Entry 22 matches the reference Encounter/mii-exa-seltene-encounter-cardiology by type and id but its fullUrl urn:uuid:c90d7e24-a787-4d1b-b402-36b64362cc13 does not match the full target URL urn:uuid:mii-exa-seltene-encounter-cardiology by Bundle resolution rules"
            },
            "expression": [
              "Bundle/mii-exa-seltene-bundle-marfan-complete: Bundle.entry[2].resource/*Condition/mii-exa-seltene-condition-marfan-clinical*/.encounter"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "BUNDLE_BUNDLE_POSSIBLE_MATCH_WRONG_FU"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/Condition|4.0.1"
              }
            ],
            "severity": "warning",
            "code": "required",
            "details": {
              "text": "Entry 9 matches the reference Observation/mii-exa-seltene-symptom-aortic-root by type and id but its fullUrl urn:uuid:a482bf38-9c7a-4295-a0f2-a38c1d15aae7 does not match the full target URL urn:uuid:mii-exa-seltene-symptom-aortic-root by Bundle resolution rules"
            },
            "expression": [
              "Bundle/mii-exa-seltene-bundle-marfan-complete: Bundle.entry[2].resource/*Condition/mii-exa-seltene-condition-marfan-clinical*/.evidence[0].detail[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "BUNDLE_BUNDLE_POSSIBLE_MATCH_WRONG_FU"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/Condition|4.0.1"
              }
            ],
            "severity": "warning",
            "code": "required",
            "details": {
              "text": "Entry 10 matches the reference Observation/mii-exa-seltene-symptom-aortic-regurg by type and id but its fullUrl urn:uuid:7b78bb46-817f-4786-84f8-0805b1580192 does not match the full target URL urn:uuid:mii-exa-seltene-symptom-aortic-regurg by Bundle resolution rules"
            },
            "expression": [
              "Bundle/mii-exa-seltene-bundle-marfan-complete: Bundle.entry[2].resource/*Condition/mii-exa-seltene-condition-marfan-clinical*/.evidence[1].detail[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "BUNDLE_BUNDLE_POSSIBLE_MATCH_WRONG_FU"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/Condition|4.0.1"
              }
            ],
            "severity": "warning",
            "code": "required",
            "details": {
              "text": "Entry 11 matches the reference Observation/mii-exa-seltene-symptom-mitral-regurg by type and id but its fullUrl urn:uuid:a933aaca-920c-4d29-be34-1d38c60b8bc9 does not match the full target URL urn:uuid:mii-exa-seltene-symptom-mitral-regurg by Bundle resolution rules"
            },
            "expression": [
              "Bundle/mii-exa-seltene-bundle-marfan-complete: Bundle.entry[2].resource/*Condition/mii-exa-seltene-condition-marfan-clinical*/.evidence[2].detail[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "BUNDLE_BUNDLE_POSSIBLE_MATCH_WRONG_FU"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/Condition|4.0.1"
              }
            ],
            "severity": "warning",
            "code": "required",
            "details": {
              "text": "Entry 5 matches the reference Observation/mii-exa-seltene-observation-height-001 by type and id but its fullUrl urn:uuid:72fa4681-014d-4caa-86a3-97cea92766f4 does not match the full target URL urn:uuid:mii-exa-seltene-observation-height-001 by Bundle resolution rules"
            },
            "expression": [
              "Bundle/mii-exa-seltene-bundle-marfan-complete: Bundle.entry[2].resource/*Condition/mii-exa-seltene-condition-marfan-clinical*/.evidence[3].detail[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "BUNDLE_BUNDLE_POSSIBLE_MATCH_WRONG_FU"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/Condition|4.0.1"
              }
            ],
            "severity": "warning",
            "code": "required",
            "details": {
              "text": "Entry 6 matches the reference Observation/mii-exa-seltene-observation-leg-asymmetry by type and id but its fullUrl urn:uuid:9dfa4ddc-723f-4c65-b86d-1a88304e77fe does not match the full target URL urn:uuid:mii-exa-seltene-observation-leg-asymmetry by Bundle resolution rules"
            },
            "expression": [
              "Bundle/mii-exa-seltene-bundle-marfan-complete: Bundle.entry[2].resource/*Condition/mii-exa-seltene-condition-marfan-clinical*/.evidence[4].detail[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "BUNDLE_BUNDLE_POSSIBLE_MATCH_WRONG_FU"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/Condition|4.0.1"
              }
            ],
            "severity": "warning",
            "code": "required",
            "details": {
              "text": "Entry 7 matches the reference Observation/mii-exa-seltene-symptom-chest-pain by type and id but its fullUrl urn:uuid:b5f66545-2f6e-450c-a92e-8e9d2626e003 does not match the full target URL urn:uuid:mii-exa-seltene-symptom-chest-pain by Bundle resolution rules"
            },
            "expression": [
              "Bundle/mii-exa-seltene-bundle-marfan-complete: Bundle.entry[2].resource/*Condition/mii-exa-seltene-condition-marfan-clinical*/.evidence[5].detail[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 316
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/Condition|4.0.1"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'http://omim.org' version '2024' could not be found, so the code cannot be validated. No versions of this code system are known"
            },
            "expression": [
              "Bundle/mii-exa-seltene-bundle-marfan-complete: Bundle.entry[3].resource/*Condition/mii-exa-seltene-condition-marfan-genetic*/.code.coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 316
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/Condition|4.0.1"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'http://snomed.info/sct' version 'null' could not be found, so the code cannot be validated. Valid versions: [http://snomed.info/sct/900000000000207008/version/20230731, http://snomed.info/sct/900000000000207008/version/20240101, http://snomed.info/sct/900000000000207008/version/20240701, http://snomed.info/sct/11000274103/version/20241115, http://snomed.info/sct/900000000000207008/version/20250101, http://snomed.info/sct/900000000000207008/version/20250701, http://snomed.info/sct/11000274103/version/20231115, http://snomed.info/sct/11010000107/version/20250921, http://snomed.info/sct/11000274103/version/20250515, http://snomed.info/sct/11000274103/version/20240515, http://snomed.info/sct/11000274103/version/20251115, http://snomed.info/sct/900000000000207008/version/20260101, http://snomed.info/sct/900000000000207008/version/20260701, http://snomed.info/sct/11000274103/version/20260515]"
            },
            "expression": [
              "Bundle/mii-exa-seltene-bundle-marfan-complete: Bundle.entry[3].resource/*Condition/mii-exa-seltene-condition-marfan-genetic*/.code.coding[1].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 316
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/Condition|4.0.1"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'http://www.orpha.net' version 'null' could not be found, so the code cannot be validated. Valid versions: [2023, 2024, 2025]"
            },
            "expression": [
              "Bundle/mii-exa-seltene-bundle-marfan-complete: Bundle.entry[3].resource/*Condition/mii-exa-seltene-condition-marfan-genetic*/.code.coding[2].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "BUNDLE_BUNDLE_POSSIBLE_MATCH_WRONG_FU"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/Condition|4.0.1"
              }
            ],
            "severity": "warning",
            "code": "required",
            "details": {
              "text": "Entry 0 matches the reference Patient/mii-exa-seltene-patient-marfan-001 by type and id but its fullUrl urn:uuid:546740dd-771d-41e4-a2a5-e8d6a2b5c505 does not match the full target URL urn:uuid:mii-exa-seltene-patient-marfan-001 by Bundle resolution rules"
            },
            "expression": [
              "Bundle/mii-exa-seltene-bundle-marfan-complete: Bundle.entry[3].resource/*Condition/mii-exa-seltene-condition-marfan-genetic*/.subject"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "BUNDLE_BUNDLE_POSSIBLE_MATCH_WRONG_FU"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/Condition|4.0.1"
              }
            ],
            "severity": "warning",
            "code": "required",
            "details": {
              "text": "Entry 12 matches the reference Observation/mii-exa-seltene-variant-fbn1-001 by type and id but its fullUrl urn:uuid:b769b1ea-3ec2-4b35-86d2-9a0ca128e1e6 does not match the full target URL urn:uuid:mii-exa-seltene-variant-fbn1-001 by Bundle resolution rules"
            },
            "expression": [
              "Bundle/mii-exa-seltene-bundle-marfan-complete: Bundle.entry[3].resource/*Condition/mii-exa-seltene-condition-marfan-genetic*/.evidence[0].detail[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "BUNDLE_BUNDLE_POSSIBLE_MATCH_WRONG_FU"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/Condition|4.0.1"
              }
            ],
            "severity": "warning",
            "code": "required",
            "details": {
              "text": "Entry 0 matches the reference Patient/mii-exa-seltene-patient-marfan-001 by type and id but its fullUrl urn:uuid:546740dd-771d-41e4-a2a5-e8d6a2b5c505 does not match the full target URL urn:uuid:mii-exa-seltene-patient-marfan-001 by Bundle resolution rules"
            },
            "expression": [
              "Bundle/mii-exa-seltene-bundle-marfan-complete: Bundle.entry[4].resource/*Condition/mii-exa-seltene-condition-cataract*/.subject"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "BUNDLE_BUNDLE_POSSIBLE_MATCH_WRONG_FU"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/Condition|4.0.1"
              }
            ],
            "severity": "warning",
            "code": "required",
            "details": {
              "text": "Entry 20 matches the reference Encounter/mii-exa-seltene-encounter-ophthalmology by type and id but its fullUrl urn:uuid:258f0a21-4c6e-473d-87e9-36a5bf01bb1a does not match the full target URL urn:uuid:mii-exa-seltene-encounter-ophthalmology by Bundle resolution rules"
            },
            "expression": [
              "Bundle/mii-exa-seltene-bundle-marfan-complete: Bundle.entry[4].resource/*Condition/mii-exa-seltene-condition-cataract*/.encounter"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "BUNDLE_BUNDLE_POSSIBLE_MATCH_WRONG_FU"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/Condition|4.0.1"
              }
            ],
            "severity": "warning",
            "code": "required",
            "details": {
              "text": "Entry 8 matches the reference Observation/mii-exa-seltene-symptom-cataract by type and id but its fullUrl urn:uuid:ce25223c-45fe-4a87-ba1b-e120cba24e94 does not match the full target URL urn:uuid:mii-exa-seltene-symptom-cataract by Bundle resolution rules"
            },
            "expression": [
              "Bundle/mii-exa-seltene-bundle-marfan-complete: Bundle.entry[4].resource/*Condition/mii-exa-seltene-condition-cataract*/.evidence[0].detail[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "BUNDLE_BUNDLE_POSSIBLE_MATCH_WRONG_FU"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/bodyheight|4.0.1"
              }
            ],
            "severity": "warning",
            "code": "required",
            "details": {
              "text": "Entry 0 matches the reference Patient/mii-exa-seltene-patient-marfan-001 by type and id but its fullUrl urn:uuid:546740dd-771d-41e4-a2a5-e8d6a2b5c505 does not match the full target URL urn:uuid:mii-exa-seltene-patient-marfan-001 by Bundle resolution rules"
            },
            "expression": [
              "Bundle/mii-exa-seltene-bundle-marfan-complete: Bundle.entry[5].resource/*Observation/mii-exa-seltene-observation-height-001*/.subject"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 525
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Terminology_PassThrough_TX_Message"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/bodyheight|4.0.1"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "Resolved system http://unitsofmeasure.org (v3.0.1), but the definition doesn't include any codes, so the code has not been validated (for 'http://unitsofmeasure.org#cm')"
            },
            "expression": [
              "Bundle/mii-exa-seltene-bundle-marfan-complete: Bundle.entry[5].resource/*Observation/mii-exa-seltene-observation-height-001*/.value.ofType(Quantity)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 527
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 23
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/bodyheight|4.0.1"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'http://unitsofmeasure.org' could not be found, so the code cannot be validated"
            },
            "expression": [
              "Bundle/mii-exa-seltene-bundle-marfan-complete: Bundle.entry[5].resource/*Observation/mii-exa-seltene-observation-height-001*/.value.ofType(Quantity).code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 498
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "All_observations_should_have_a_performer"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Best Practice Recommendation: In general, all observations should have a performer"
            },
            "expression": [
              "Bundle/mii-exa-seltene-bundle-marfan-complete: Bundle.entry[5].resource/*Observation/mii-exa-seltene-observation-height-001*/"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 573
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "All_observations_should_have_a_performer"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Best Practice Recommendation: In general, all observations should have a performer"
            },
            "expression": [
              "Bundle/mii-exa-seltene-bundle-marfan-complete: Bundle.entry[6].resource/*Observation/mii-exa-seltene-observation-leg-asymmetry*/"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "BUNDLE_BUNDLE_POSSIBLE_MATCH_WRONG_FU"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/Observation|4.0.1"
              }
            ],
            "severity": "warning",
            "code": "required",
            "details": {
              "text": "Entry 0 matches the reference Patient/mii-exa-seltene-patient-marfan-001 by type and id but its fullUrl urn:uuid:546740dd-771d-41e4-a2a5-e8d6a2b5c505 does not match the full target URL urn:uuid:mii-exa-seltene-patient-marfan-001 by Bundle resolution rules"
            },
            "expression": [
              "Bundle/mii-exa-seltene-bundle-marfan-complete: Bundle.entry[6].resource/*Observation/mii-exa-seltene-observation-leg-asymmetry*/.subject"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 651
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "All_observations_should_have_a_performer"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Best Practice Recommendation: In general, all observations should have a performer"
            },
            "expression": [
              "Bundle/mii-exa-seltene-bundle-marfan-complete: Bundle.entry[7].resource/*Observation/mii-exa-seltene-symptom-chest-pain*/"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "BUNDLE_BUNDLE_POSSIBLE_MATCH_WRONG_FU"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/Observation|4.0.1"
              }
            ],
            "severity": "warning",
            "code": "required",
            "details": {
              "text": "Entry 0 matches the reference Patient/mii-exa-seltene-patient-marfan-001 by type and id but its fullUrl urn:uuid:546740dd-771d-41e4-a2a5-e8d6a2b5c505 does not match the full target URL urn:uuid:mii-exa-seltene-patient-marfan-001 by Bundle resolution rules"
            },
            "expression": [
              "Bundle/mii-exa-seltene-bundle-marfan-complete: Bundle.entry[7].resource/*Observation/mii-exa-seltene-symptom-chest-pain*/.subject"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 712
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "All_observations_should_have_a_performer"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Best Practice Recommendation: In general, all observations should have a performer"
            },
            "expression": [
              "Bundle/mii-exa-seltene-bundle-marfan-complete: Bundle.entry[8].resource/*Observation/mii-exa-seltene-symptom-cataract*/"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "BUNDLE_BUNDLE_POSSIBLE_MATCH_WRONG_FU"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/Observation|4.0.1"
              }
            ],
            "severity": "warning",
            "code": "required",
            "details": {
              "text": "Entry 0 matches the reference Patient/mii-exa-seltene-patient-marfan-001 by type and id but its fullUrl urn:uuid:546740dd-771d-41e4-a2a5-e8d6a2b5c505 does not match the full target URL urn:uuid:mii-exa-seltene-patient-marfan-001 by Bundle resolution rules"
            },
            "expression": [
              "Bundle/mii-exa-seltene-bundle-marfan-complete: Bundle.entry[8].resource/*Observation/mii-exa-seltene-symptom-cataract*/.subject"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 782
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "All_observations_should_have_a_performer"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Best Practice Recommendation: In general, all observations should have a performer"
            },
            "expression": [
              "Bundle/mii-exa-seltene-bundle-marfan-complete: Bundle.entry[9].resource/*Observation/mii-exa-seltene-symptom-aortic-root*/"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "BUNDLE_BUNDLE_POSSIBLE_MATCH_WRONG_FU"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/Observation|4.0.1"
              }
            ],
            "severity": "warning",
            "code": "required",
            "details": {
              "text": "Entry 0 matches the reference Patient/mii-exa-seltene-patient-marfan-001 by type and id but its fullUrl urn:uuid:546740dd-771d-41e4-a2a5-e8d6a2b5c505 does not match the full target URL urn:uuid:mii-exa-seltene-patient-marfan-001 by Bundle resolution rules"
            },
            "expression": [
              "Bundle/mii-exa-seltene-bundle-marfan-complete: Bundle.entry[9].resource/*Observation/mii-exa-seltene-symptom-aortic-root*/.subject"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 815
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Terminology_PassThrough_TX_Message"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/Observation|4.0.1"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "Resolved system http://unitsofmeasure.org (v3.0.1), but the definition doesn't include any codes, so the code has not been validated (for 'http://unitsofmeasure.org#mm')"
            },
            "expression": [
              "Bundle/mii-exa-seltene-bundle-marfan-complete: Bundle.entry[9].resource/*Observation/mii-exa-seltene-symptom-aortic-root*/.value.ofType(Quantity)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 849
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "All_observations_should_have_a_performer"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Best Practice Recommendation: In general, all observations should have a performer"
            },
            "expression": [
              "Bundle/mii-exa-seltene-bundle-marfan-complete: Bundle.entry[10].resource/*Observation/mii-exa-seltene-symptom-aortic-regurg*/"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "BUNDLE_BUNDLE_POSSIBLE_MATCH_WRONG_FU"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/Observation|4.0.1"
              }
            ],
            "severity": "warning",
            "code": "required",
            "details": {
              "text": "Entry 0 matches the reference Patient/mii-exa-seltene-patient-marfan-001 by type and id but its fullUrl urn:uuid:546740dd-771d-41e4-a2a5-e8d6a2b5c505 does not match the full target URL urn:uuid:mii-exa-seltene-patient-marfan-001 by Bundle resolution rules"
            },
            "expression": [
              "Bundle/mii-exa-seltene-bundle-marfan-complete: Bundle.entry[10].resource/*Observation/mii-exa-seltene-symptom-aortic-regurg*/.subject"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 911
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "All_observations_should_have_a_performer"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Best Practice Recommendation: In general, all observations should have a performer"
            },
            "expression": [
              "Bundle/mii-exa-seltene-bundle-marfan-complete: Bundle.entry[11].resource/*Observation/mii-exa-seltene-symptom-mitral-regurg*/"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "BUNDLE_BUNDLE_POSSIBLE_MATCH_WRONG_FU"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/Observation|4.0.1"
              }
            ],
            "severity": "warning",
            "code": "required",
            "details": {
              "text": "Entry 0 matches the reference Patient/mii-exa-seltene-patient-marfan-001 by type and id but its fullUrl urn:uuid:546740dd-771d-41e4-a2a5-e8d6a2b5c505 does not match the full target URL urn:uuid:mii-exa-seltene-patient-marfan-001 by Bundle resolution rules"
            },
            "expression": [
              "Bundle/mii-exa-seltene-bundle-marfan-complete: Bundle.entry[11].resource/*Observation/mii-exa-seltene-symptom-mitral-regurg*/.subject"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 973
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "All_observations_should_have_a_performer"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Best Practice Recommendation: In general, all observations should have a performer"
            },
            "expression": [
              "Bundle/mii-exa-seltene-bundle-marfan-complete: Bundle.entry[12].resource/*Observation/mii-exa-seltene-variant-fbn1-001*/"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "BUNDLE_BUNDLE_POSSIBLE_MATCH_WRONG_FU"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/Observation|4.0.1"
              }
            ],
            "severity": "warning",
            "code": "required",
            "details": {
              "text": "Entry 0 matches the reference Patient/mii-exa-seltene-patient-marfan-001 by type and id but its fullUrl urn:uuid:546740dd-771d-41e4-a2a5-e8d6a2b5c505 does not match the full target URL urn:uuid:mii-exa-seltene-patient-marfan-001 by Bundle resolution rules"
            },
            "expression": [
              "Bundle/mii-exa-seltene-bundle-marfan-complete: Bundle.entry[12].resource/*Observation/mii-exa-seltene-variant-fbn1-001*/.subject"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1103
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "All_observations_should_have_a_performer"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Best Practice Recommendation: In general, all observations should have a performer"
            },
            "expression": [
              "Bundle/mii-exa-seltene-bundle-marfan-complete: Bundle.entry[13].resource/*Observation/mii-exa-seltene-observation-echo-aortic*/"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "BUNDLE_BUNDLE_POSSIBLE_MATCH_WRONG_FU"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/Observation|4.0.1"
              }
            ],
            "severity": "warning",
            "code": "required",
            "details": {
              "text": "Entry 0 matches the reference Patient/mii-exa-seltene-patient-marfan-001 by type and id but its fullUrl urn:uuid:546740dd-771d-41e4-a2a5-e8d6a2b5c505 does not match the full target URL urn:uuid:mii-exa-seltene-patient-marfan-001 by Bundle resolution rules"
            },
            "expression": [
              "Bundle/mii-exa-seltene-bundle-marfan-complete: Bundle.entry[13].resource/*Observation/mii-exa-seltene-observation-echo-aortic*/.subject"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1130
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Terminology_PassThrough_TX_Message"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/Observation|4.0.1"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "Resolved system http://unitsofmeasure.org (v3.0.1), but the definition doesn't include any codes, so the code has not been validated (for 'http://unitsofmeasure.org#mm')"
            },
            "expression": [
              "Bundle/mii-exa-seltene-bundle-marfan-complete: Bundle.entry[13].resource/*Observation/mii-exa-seltene-observation-echo-aortic*/.value.ofType(Quantity)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1164
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "All_observations_should_have_a_performer"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Best Practice Recommendation: In general, all observations should have a performer"
            },
            "expression": [
              "Bundle/mii-exa-seltene-bundle-marfan-complete: Bundle.entry[14].resource/*Observation/mii-exa-seltene-observation-echo-av*/"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "BUNDLE_BUNDLE_POSSIBLE_MATCH_WRONG_FU"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/Observation|4.0.1"
              }
            ],
            "severity": "warning",
            "code": "required",
            "details": {
              "text": "Entry 0 matches the reference Patient/mii-exa-seltene-patient-marfan-001 by type and id but its fullUrl urn:uuid:546740dd-771d-41e4-a2a5-e8d6a2b5c505 does not match the full target URL urn:uuid:mii-exa-seltene-patient-marfan-001 by Bundle resolution rules"
            },
            "expression": [
              "Bundle/mii-exa-seltene-bundle-marfan-complete: Bundle.entry[14].resource/*Observation/mii-exa-seltene-observation-echo-av*/.subject"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1222
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "All_observations_should_have_a_performer"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Best Practice Recommendation: In general, all observations should have a performer"
            },
            "expression": [
              "Bundle/mii-exa-seltene-bundle-marfan-complete: Bundle.entry[15].resource/*Observation/mii-exa-seltene-observation-echo-mv*/"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "BUNDLE_BUNDLE_POSSIBLE_MATCH_WRONG_FU"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/Observation|4.0.1"
              }
            ],
            "severity": "warning",
            "code": "required",
            "details": {
              "text": "Entry 0 matches the reference Patient/mii-exa-seltene-patient-marfan-001 by type and id but its fullUrl urn:uuid:546740dd-771d-41e4-a2a5-e8d6a2b5c505 does not match the full target URL urn:uuid:mii-exa-seltene-patient-marfan-001 by Bundle resolution rules"
            },
            "expression": [
              "Bundle/mii-exa-seltene-bundle-marfan-complete: Bundle.entry[15].resource/*Observation/mii-exa-seltene-observation-echo-mv*/.subject"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "BUNDLE_BUNDLE_POSSIBLE_MATCH_WRONG_FU"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/Procedure|4.0.1"
              }
            ],
            "severity": "warning",
            "code": "required",
            "details": {
              "text": "Entry 0 matches the reference Patient/mii-exa-seltene-patient-marfan-001 by type and id but its fullUrl urn:uuid:546740dd-771d-41e4-a2a5-e8d6a2b5c505 does not match the full target URL urn:uuid:mii-exa-seltene-patient-marfan-001 by Bundle resolution rules"
            },
            "expression": [
              "Bundle/mii-exa-seltene-bundle-marfan-complete: Bundle.entry[16].resource/*Procedure/mii-exa-seltene-procedure-cataract-surgery*/.subject"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "BUNDLE_BUNDLE_POSSIBLE_MATCH_WRONG_FU"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/Procedure|4.0.1"
              }
            ],
            "severity": "warning",
            "code": "required",
            "details": {
              "text": "Entry 4 matches the reference Condition/mii-exa-seltene-condition-cataract by type and id but its fullUrl urn:uuid:f584ef12-6225-4e71-9186-68528f68e07d does not match the full target URL urn:uuid:mii-exa-seltene-condition-cataract by Bundle resolution rules"
            },
            "expression": [
              "Bundle/mii-exa-seltene-bundle-marfan-complete: Bundle.entry[16].resource/*Procedure/mii-exa-seltene-procedure-cataract-surgery*/.reasonReference[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "BUNDLE_BUNDLE_POSSIBLE_MATCH_WRONG_FU"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/Procedure|4.0.1"
              }
            ],
            "severity": "warning",
            "code": "required",
            "details": {
              "text": "Entry 0 matches the reference Patient/mii-exa-seltene-patient-marfan-001 by type and id but its fullUrl urn:uuid:546740dd-771d-41e4-a2a5-e8d6a2b5c505 does not match the full target URL urn:uuid:mii-exa-seltene-patient-marfan-001 by Bundle resolution rules"
            },
            "expression": [
              "Bundle/mii-exa-seltene-bundle-marfan-complete: Bundle.entry[17].resource/*Procedure/mii-exa-seltene-procedure-aortic-planned*/.subject"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "BUNDLE_BUNDLE_POSSIBLE_MATCH_WRONG_FU"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/Procedure|4.0.1"
              }
            ],
            "severity": "warning",
            "code": "required",
            "details": {
              "text": "Entry 2 matches the reference Condition/mii-exa-seltene-condition-marfan-clinical by type and id but its fullUrl urn:uuid:6842a03b-9adc-4cb7-9126-85d317203e7b does not match the full target URL urn:uuid:mii-exa-seltene-condition-marfan-clinical by Bundle resolution rules"
            },
            "expression": [
              "Bundle/mii-exa-seltene-bundle-marfan-complete: Bundle.entry[17].resource/*Procedure/mii-exa-seltene-procedure-aortic-planned*/.reasonReference[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "BUNDLE_BUNDLE_POSSIBLE_MATCH_WRONG_FU"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/MedicationStatement|4.0.1"
              }
            ],
            "severity": "warning",
            "code": "required",
            "details": {
              "text": "Entry 0 matches the reference Patient/mii-exa-seltene-patient-marfan-001 by type and id but its fullUrl urn:uuid:546740dd-771d-41e4-a2a5-e8d6a2b5c505 does not match the full target URL urn:uuid:mii-exa-seltene-patient-marfan-001 by Bundle resolution rules"
            },
            "expression": [
              "Bundle/mii-exa-seltene-bundle-marfan-complete: Bundle.entry[18].resource/*MedicationStatement/mii-exa-seltene-medication-losartan*/.subject"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "BUNDLE_BUNDLE_POSSIBLE_MATCH_WRONG_FU"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/MedicationStatement|4.0.1"
              }
            ],
            "severity": "warning",
            "code": "required",
            "details": {
              "text": "Entry 2 matches the reference Condition/mii-exa-seltene-condition-marfan-clinical by type and id but its fullUrl urn:uuid:6842a03b-9adc-4cb7-9126-85d317203e7b does not match the full target URL urn:uuid:mii-exa-seltene-condition-marfan-clinical by Bundle resolution rules"
            },
            "expression": [
              "Bundle/mii-exa-seltene-bundle-marfan-complete: Bundle.entry[18].resource/*MedicationStatement/mii-exa-seltene-medication-losartan*/.reasonReference[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1439
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 34
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/MedicationStatement|4.0.1"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "A definition for CodeSystem 'null' could not be found, so the code cannot be validated"
            },
            "expression": [
              "Bundle/mii-exa-seltene-bundle-marfan-complete: Bundle.entry[18].resource/*MedicationStatement/mii-exa-seltene-medication-losartan*/.dosage[0].timing.repeat.periodUnit"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1427
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 18
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Terminology_PassThrough_TX_Message"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/MedicationStatement|4.0.1"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "Resolved system http://unitsofmeasure.org (v3.0.1), but the definition doesn't include any codes, so the code has not been validated (for 'http://unitsofmeasure.org#mg')"
            },
            "expression": [
              "Bundle/mii-exa-seltene-bundle-marfan-complete: Bundle.entry[18].resource/*MedicationStatement/mii-exa-seltene-medication-losartan*/.dosage[0].doseAndRate[0].dose.ofType(Quantity)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "BUNDLE_BUNDLE_POSSIBLE_MATCH_WRONG_FU"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/ClinicalImpression|4.0.1"
              }
            ],
            "severity": "warning",
            "code": "required",
            "details": {
              "text": "Entry 0 matches the reference Patient/mii-exa-seltene-patient-marfan-001 by type and id but its fullUrl urn:uuid:546740dd-771d-41e4-a2a5-e8d6a2b5c505 does not match the full target URL urn:uuid:mii-exa-seltene-patient-marfan-001 by Bundle resolution rules"
            },
            "expression": [
              "Bundle/mii-exa-seltene-bundle-marfan-complete: Bundle.entry[19].resource/*ClinicalImpression/mii-exa-seltene-clinical-impression-seltene-assessment*/.subject"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "BUNDLE_BUNDLE_POSSIBLE_MATCH_WRONG_FU"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/ClinicalImpression|4.0.1"
              }
            ],
            "severity": "warning",
            "code": "required",
            "details": {
              "text": "Entry 22 matches the reference Encounter/mii-exa-seltene-encounter-cardiology by type and id but its fullUrl urn:uuid:c90d7e24-a787-4d1b-b402-36b64362cc13 does not match the full target URL urn:uuid:mii-exa-seltene-encounter-cardiology by Bundle resolution rules"
            },
            "expression": [
              "Bundle/mii-exa-seltene-bundle-marfan-complete: Bundle.entry[19].resource/*ClinicalImpression/mii-exa-seltene-clinical-impression-seltene-assessment*/.encounter"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "BUNDLE_BUNDLE_POSSIBLE_MATCH_WRONG_FU"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/ClinicalImpression|4.0.1"
              }
            ],
            "severity": "warning",
            "code": "required",
            "details": {
              "text": "Entry 1 matches the reference Condition/mii-exa-seltene-condition-marfan-suspected by type and id but its fullUrl urn:uuid:12b18efe-aae8-4039-9e2c-466ee0cb0ce0 does not match the full target URL urn:uuid:mii-exa-seltene-condition-marfan-suspected by Bundle resolution rules"
            },
            "expression": [
              "Bundle/mii-exa-seltene-bundle-marfan-complete: Bundle.entry[19].resource/*ClinicalImpression/mii-exa-seltene-clinical-impression-seltene-assessment*/.problem[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "BUNDLE_BUNDLE_POSSIBLE_MATCH_WRONG_FU"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/ClinicalImpression|4.0.1"
              }
            ],
            "severity": "warning",
            "code": "required",
            "details": {
              "text": "Entry 2 matches the reference Condition/mii-exa-seltene-condition-marfan-clinical by type and id but its fullUrl urn:uuid:6842a03b-9adc-4cb7-9126-85d317203e7b does not match the full target URL urn:uuid:mii-exa-seltene-condition-marfan-clinical by Bundle resolution rules"
            },
            "expression": [
              "Bundle/mii-exa-seltene-bundle-marfan-complete: Bundle.entry[19].resource/*ClinicalImpression/mii-exa-seltene-clinical-impression-seltene-assessment*/.problem[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "BUNDLE_BUNDLE_POSSIBLE_MATCH_WRONG_FU"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/ClinicalImpression|4.0.1"
              }
            ],
            "severity": "warning",
            "code": "required",
            "details": {
              "text": "Entry 3 matches the reference Condition/mii-exa-seltene-condition-marfan-genetic by type and id but its fullUrl urn:uuid:23bd27f8-f2b5-4bc9-8fa3-078c26bc64a2 does not match the full target URL urn:uuid:mii-exa-seltene-condition-marfan-genetic by Bundle resolution rules"
            },
            "expression": [
              "Bundle/mii-exa-seltene-bundle-marfan-complete: Bundle.entry[19].resource/*ClinicalImpression/mii-exa-seltene-clinical-impression-seltene-assessment*/.problem[2]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "BUNDLE_BUNDLE_POSSIBLE_MATCH_WRONG_FU"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/ClinicalImpression|4.0.1"
              }
            ],
            "severity": "warning",
            "code": "required",
            "details": {
              "text": "Entry 13 matches the reference Observation/mii-exa-seltene-observation-echo-aortic by type and id but its fullUrl urn:uuid:b4d84fa0-2c48-4613-ba4f-05b75d83c3c9 does not match the full target URL urn:uuid:mii-exa-seltene-observation-echo-aortic by Bundle resolution rules"
            },
            "expression": [
              "Bundle/mii-exa-seltene-bundle-marfan-complete: Bundle.entry[19].resource/*ClinicalImpression/mii-exa-seltene-clinical-impression-seltene-assessment*/.investigation[0].item[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "BUNDLE_BUNDLE_POSSIBLE_MATCH_WRONG_FU"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/ClinicalImpression|4.0.1"
              }
            ],
            "severity": "warning",
            "code": "required",
            "details": {
              "text": "Entry 14 matches the reference Observation/mii-exa-seltene-observation-echo-av by type and id but its fullUrl urn:uuid:796c77be-100b-4935-b738-ef8d6175d668 does not match the full target URL urn:uuid:mii-exa-seltene-observation-echo-av by Bundle resolution rules"
            },
            "expression": [
              "Bundle/mii-exa-seltene-bundle-marfan-complete: Bundle.entry[19].resource/*ClinicalImpression/mii-exa-seltene-clinical-impression-seltene-assessment*/.investigation[0].item[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "BUNDLE_BUNDLE_POSSIBLE_MATCH_WRONG_FU"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/ClinicalImpression|4.0.1"
              }
            ],
            "severity": "warning",
            "code": "required",
            "details": {
              "text": "Entry 15 matches the reference Observation/mii-exa-seltene-observation-echo-mv by type and id but its fullUrl urn:uuid:c9a2b002-1177-4c4e-82c0-a8d32983da28 does not match the full target URL urn:uuid:mii-exa-seltene-observation-echo-mv by Bundle resolution rules"
            },
            "expression": [
              "Bundle/mii-exa-seltene-bundle-marfan-complete: Bundle.entry[19].resource/*ClinicalImpression/mii-exa-seltene-clinical-impression-seltene-assessment*/.investigation[0].item[2]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "BUNDLE_BUNDLE_POSSIBLE_MATCH_WRONG_FU"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/ClinicalImpression|4.0.1"
              }
            ],
            "severity": "warning",
            "code": "required",
            "details": {
              "text": "Entry 2 matches the reference Condition/mii-exa-seltene-condition-marfan-clinical by type and id but its fullUrl urn:uuid:6842a03b-9adc-4cb7-9126-85d317203e7b does not match the full target URL urn:uuid:mii-exa-seltene-condition-marfan-clinical by Bundle resolution rules"
            },
            "expression": [
              "Bundle/mii-exa-seltene-bundle-marfan-complete: Bundle.entry[19].resource/*ClinicalImpression/mii-exa-seltene-clinical-impression-seltene-assessment*/.finding[0].itemReference"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "BUNDLE_BUNDLE_POSSIBLE_MATCH_WRONG_FU"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/ClinicalImpression|4.0.1"
              }
            ],
            "severity": "warning",
            "code": "required",
            "details": {
              "text": "Entry 3 matches the reference Condition/mii-exa-seltene-condition-marfan-genetic by type and id but its fullUrl urn:uuid:23bd27f8-f2b5-4bc9-8fa3-078c26bc64a2 does not match the full target URL urn:uuid:mii-exa-seltene-condition-marfan-genetic by Bundle resolution rules"
            },
            "expression": [
              "Bundle/mii-exa-seltene-bundle-marfan-complete: Bundle.entry[19].resource/*ClinicalImpression/mii-exa-seltene-clinical-impression-seltene-assessment*/.finding[1].itemReference"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "BUNDLE_BUNDLE_POSSIBLE_MATCH_WRONG_FU"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/ClinicalImpression|4.0.1"
              }
            ],
            "severity": "warning",
            "code": "required",
            "details": {
              "text": "Entry 9 matches the reference Observation/mii-exa-seltene-symptom-aortic-root by type and id but its fullUrl urn:uuid:a482bf38-9c7a-4295-a0f2-a38c1d15aae7 does not match the full target URL urn:uuid:mii-exa-seltene-symptom-aortic-root by Bundle resolution rules"
            },
            "expression": [
              "Bundle/mii-exa-seltene-bundle-marfan-complete: Bundle.entry[19].resource/*ClinicalImpression/mii-exa-seltene-clinical-impression-seltene-assessment*/.finding[2].itemReference"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "BUNDLE_BUNDLE_POSSIBLE_MATCH_WRONG_FU"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/ClinicalImpression|4.0.1"
              }
            ],
            "severity": "warning",
            "code": "required",
            "details": {
              "text": "Entry 10 matches the reference Observation/mii-exa-seltene-symptom-aortic-regurg by type and id but its fullUrl urn:uuid:7b78bb46-817f-4786-84f8-0805b1580192 does not match the full target URL urn:uuid:mii-exa-seltene-symptom-aortic-regurg by Bundle resolution rules"
            },
            "expression": [
              "Bundle/mii-exa-seltene-bundle-marfan-complete: Bundle.entry[19].resource/*ClinicalImpression/mii-exa-seltene-clinical-impression-seltene-assessment*/.finding[3].itemReference"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "BUNDLE_BUNDLE_POSSIBLE_MATCH_WRONG_FU"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/ClinicalImpression|4.0.1"
              }
            ],
            "severity": "warning",
            "code": "required",
            "details": {
              "text": "Entry 11 matches the reference Observation/mii-exa-seltene-symptom-mitral-regurg by type and id but its fullUrl urn:uuid:a933aaca-920c-4d29-be34-1d38c60b8bc9 does not match the full target URL urn:uuid:mii-exa-seltene-symptom-mitral-regurg by Bundle resolution rules"
            },
            "expression": [
              "Bundle/mii-exa-seltene-bundle-marfan-complete: Bundle.entry[19].resource/*ClinicalImpression/mii-exa-seltene-clinical-impression-seltene-assessment*/.finding[4].itemReference"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "BUNDLE_BUNDLE_POSSIBLE_MATCH_WRONG_FU"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/ClinicalImpression|4.0.1"
              }
            ],
            "severity": "warning",
            "code": "required",
            "details": {
              "text": "Entry 5 matches the reference Observation/mii-exa-seltene-observation-height-001 by type and id but its fullUrl urn:uuid:72fa4681-014d-4caa-86a3-97cea92766f4 does not match the full target URL urn:uuid:mii-exa-seltene-observation-height-001 by Bundle resolution rules"
            },
            "expression": [
              "Bundle/mii-exa-seltene-bundle-marfan-complete: Bundle.entry[19].resource/*ClinicalImpression/mii-exa-seltene-clinical-impression-seltene-assessment*/.finding[5].itemReference"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "BUNDLE_BUNDLE_POSSIBLE_MATCH_WRONG_FU"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/ClinicalImpression|4.0.1"
              }
            ],
            "severity": "warning",
            "code": "required",
            "details": {
              "text": "Entry 6 matches the reference Observation/mii-exa-seltene-observation-leg-asymmetry by type and id but its fullUrl urn:uuid:9dfa4ddc-723f-4c65-b86d-1a88304e77fe does not match the full target URL urn:uuid:mii-exa-seltene-observation-leg-asymmetry by Bundle resolution rules"
            },
            "expression": [
              "Bundle/mii-exa-seltene-bundle-marfan-complete: Bundle.entry[19].resource/*ClinicalImpression/mii-exa-seltene-clinical-impression-seltene-assessment*/.finding[6].itemReference"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "BUNDLE_BUNDLE_POSSIBLE_MATCH_WRONG_FU"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/Encounter|4.0.1"
              }
            ],
            "severity": "warning",
            "code": "required",
            "details": {
              "text": "Entry 0 matches the reference Patient/mii-exa-seltene-patient-marfan-001 by type and id but its fullUrl urn:uuid:546740dd-771d-41e4-a2a5-e8d6a2b5c505 does not match the full target URL urn:uuid:mii-exa-seltene-patient-marfan-001 by Bundle resolution rules"
            },
            "expression": [
              "Bundle/mii-exa-seltene-bundle-marfan-complete: Bundle.entry[20].resource/*Encounter/mii-exa-seltene-encounter-ophthalmology*/.subject"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "BUNDLE_BUNDLE_POSSIBLE_MATCH_WRONG_FU"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/Encounter|4.0.1"
              }
            ],
            "severity": "warning",
            "code": "required",
            "details": {
              "text": "Entry 4 matches the reference Condition/mii-exa-seltene-condition-cataract by type and id but its fullUrl urn:uuid:f584ef12-6225-4e71-9186-68528f68e07d does not match the full target URL urn:uuid:mii-exa-seltene-condition-cataract by Bundle resolution rules"
            },
            "expression": [
              "Bundle/mii-exa-seltene-bundle-marfan-complete: Bundle.entry[20].resource/*Encounter/mii-exa-seltene-encounter-ophthalmology*/.diagnosis[0].condition"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "BUNDLE_BUNDLE_POSSIBLE_MATCH_WRONG_FU"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/Encounter|4.0.1"
              }
            ],
            "severity": "warning",
            "code": "required",
            "details": {
              "text": "Entry 0 matches the reference Patient/mii-exa-seltene-patient-marfan-001 by type and id but its fullUrl urn:uuid:546740dd-771d-41e4-a2a5-e8d6a2b5c505 does not match the full target URL urn:uuid:mii-exa-seltene-patient-marfan-001 by Bundle resolution rules"
            },
            "expression": [
              "Bundle/mii-exa-seltene-bundle-marfan-complete: Bundle.entry[21].resource/*Encounter/mii-exa-seltene-encounter-cataract-surgery*/.subject"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "BUNDLE_BUNDLE_POSSIBLE_MATCH_WRONG_FU"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/Encounter|4.0.1"
              }
            ],
            "severity": "warning",
            "code": "required",
            "details": {
              "text": "Entry 4 matches the reference Condition/mii-exa-seltene-condition-cataract by type and id but its fullUrl urn:uuid:f584ef12-6225-4e71-9186-68528f68e07d does not match the full target URL urn:uuid:mii-exa-seltene-condition-cataract by Bundle resolution rules"
            },
            "expression": [
              "Bundle/mii-exa-seltene-bundle-marfan-complete: Bundle.entry[21].resource/*Encounter/mii-exa-seltene-encounter-cataract-surgery*/.diagnosis[0].condition"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "BUNDLE_BUNDLE_POSSIBLE_MATCH_WRONG_FU"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/Encounter|4.0.1"
              }
            ],
            "severity": "warning",
            "code": "required",
            "details": {
              "text": "Entry 0 matches the reference Patient/mii-exa-seltene-patient-marfan-001 by type and id but its fullUrl urn:uuid:546740dd-771d-41e4-a2a5-e8d6a2b5c505 does not match the full target URL urn:uuid:mii-exa-seltene-patient-marfan-001 by Bundle resolution rules"
            },
            "expression": [
              "Bundle/mii-exa-seltene-bundle-marfan-complete: Bundle.entry[22].resource/*Encounter/mii-exa-seltene-encounter-cardiology*/.subject"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "BUNDLE_BUNDLE_POSSIBLE_MATCH_WRONG_FU"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/Encounter|4.0.1"
              }
            ],
            "severity": "warning",
            "code": "required",
            "details": {
              "text": "Entry 2 matches the reference Condition/mii-exa-seltene-condition-marfan-clinical by type and id but its fullUrl urn:uuid:6842a03b-9adc-4cb7-9126-85d317203e7b does not match the full target URL urn:uuid:mii-exa-seltene-condition-marfan-clinical by Bundle resolution rules"
            },
            "expression": [
              "Bundle/mii-exa-seltene-bundle-marfan-complete: Bundle.entry[22].resource/*Encounter/mii-exa-seltene-encounter-cardiology*/.diagnosis[0].condition"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "BUNDLE_BUNDLE_POSSIBLE_MATCH_WRONG_FU"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/Encounter|4.0.1"
              }
            ],
            "severity": "warning",
            "code": "required",
            "details": {
              "text": "Entry 0 matches the reference Patient/mii-exa-seltene-patient-marfan-001 by type and id but its fullUrl urn:uuid:546740dd-771d-41e4-a2a5-e8d6a2b5c505 does not match the full target URL urn:uuid:mii-exa-seltene-patient-marfan-001 by Bundle resolution rules"
            },
            "expression": [
              "Bundle/mii-exa-seltene-bundle-marfan-complete: Bundle.entry[23].resource/*Encounter/mii-exa-seltene-encounter-surgery-planned*/.subject"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "BUNDLE_BUNDLE_POSSIBLE_MATCH_WRONG_FU"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/Encounter|4.0.1"
              }
            ],
            "severity": "warning",
            "code": "required",
            "details": {
              "text": "Entry 2 matches the reference Condition/mii-exa-seltene-condition-marfan-clinical by type and id but its fullUrl urn:uuid:6842a03b-9adc-4cb7-9126-85d317203e7b does not match the full target URL urn:uuid:mii-exa-seltene-condition-marfan-clinical by Bundle resolution rules"
            },
            "expression": [
              "Bundle/mii-exa-seltene-bundle-marfan-complete: Bundle.entry[23].resource/*Encounter/mii-exa-seltene-encounter-surgery-planned*/.diagnosis[0].condition"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/OperationOutcome/Bundle-mii-exa-seltene-bundle-sma-complete",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Bundle-mii-exa-seltene-bundle-sma-complete",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 14
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 88
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/Patient|4.0.1"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/sid/patient-id'"
            },
            "expression": [
              "Bundle/mii-exa-seltene-bundle-sma-complete: Bundle.entry[0].resource/*Patient/mii-exa-seltene-patient-sma-001*/.identifier[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "BUNDLE_BUNDLE_POSSIBLE_MATCH_WRONG_FU"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/Condition|4.0.1"
              }
            ],
            "severity": "warning",
            "code": "required",
            "details": {
              "text": "Entry 0 matches the reference Patient/mii-exa-seltene-patient-sma-001 by type and id but its fullUrl urn:uuid:6830d99e-9bbe-48ed-8927-ff28eadc42e0 does not match the full target URL urn:uuid:mii-exa-seltene-patient-sma-001 by Bundle resolution rules"
            },
            "expression": [
              "Bundle/mii-exa-seltene-bundle-sma-complete: Bundle.entry[1].resource/*Condition/mii-exa-seltene-condition-sma-suspected*/.subject"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "BUNDLE_BUNDLE_POSSIBLE_MATCH_WRONG_FU"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/Condition|4.0.1"
              }
            ],
            "severity": "warning",
            "code": "required",
            "details": {
              "text": "Entry 18 matches the reference Encounter/mii-exa-seltene-encounter-screening-001 by type and id but its fullUrl urn:uuid:8320638f-eca2-4586-b173-bd0c49d9ae9d does not match the full target URL urn:uuid:mii-exa-seltene-encounter-screening-001 by Bundle resolution rules"
            },
            "expression": [
              "Bundle/mii-exa-seltene-bundle-sma-complete: Bundle.entry[1].resource/*Condition/mii-exa-seltene-condition-sma-suspected*/.encounter"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "BUNDLE_BUNDLE_POSSIBLE_MATCH_WRONG_FU"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/Condition|4.0.1"
              }
            ],
            "severity": "warning",
            "code": "required",
            "details": {
              "text": "Entry 5 matches the reference Observation/mii-exa-seltene-observation-sma-screening by type and id but its fullUrl urn:uuid:07ff35a6-561b-4a3b-bfc0-be528e6ab5a4 does not match the full target URL urn:uuid:mii-exa-seltene-observation-sma-screening by Bundle resolution rules"
            },
            "expression": [
              "Bundle/mii-exa-seltene-bundle-sma-complete: Bundle.entry[1].resource/*Condition/mii-exa-seltene-condition-sma-suspected*/.evidence[0].detail[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "BUNDLE_BUNDLE_POSSIBLE_MATCH_WRONG_FU"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/Condition|4.0.1"
              }
            ],
            "severity": "warning",
            "code": "required",
            "details": {
              "text": "Entry 0 matches the reference Patient/mii-exa-seltene-patient-sma-001 by type and id but its fullUrl urn:uuid:6830d99e-9bbe-48ed-8927-ff28eadc42e0 does not match the full target URL urn:uuid:mii-exa-seltene-patient-sma-001 by Bundle resolution rules"
            },
            "expression": [
              "Bundle/mii-exa-seltene-bundle-sma-complete: Bundle.entry[2].resource/*Condition/mii-exa-seltene-condition-sma-clinical*/.subject"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "BUNDLE_BUNDLE_POSSIBLE_MATCH_WRONG_FU"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/Condition|4.0.1"
              }
            ],
            "severity": "warning",
            "code": "required",
            "details": {
              "text": "Entry 19 matches the reference Encounter/mii-exa-seltene-encounter-ambulant-001 by type and id but its fullUrl urn:uuid:98afd481-d1d6-4c2e-9d1c-51c651964e5f does not match the full target URL urn:uuid:mii-exa-seltene-encounter-ambulant-001 by Bundle resolution rules"
            },
            "expression": [
              "Bundle/mii-exa-seltene-bundle-sma-complete: Bundle.entry[2].resource/*Condition/mii-exa-seltene-condition-sma-clinical*/.encounter"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "BUNDLE_BUNDLE_POSSIBLE_MATCH_WRONG_FU"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/Condition|4.0.1"
              }
            ],
            "severity": "warning",
            "code": "required",
            "details": {
              "text": "Entry 12 matches the reference Observation/mii-exa-seltene-observation-troponin-001 by type and id but its fullUrl urn:uuid:ab5b69cf-4eae-4aa3-8ce4-5b5eb1a4a46a does not match the full target URL urn:uuid:mii-exa-seltene-observation-troponin-001 by Bundle resolution rules"
            },
            "expression": [
              "Bundle/mii-exa-seltene-bundle-sma-complete: Bundle.entry[2].resource/*Condition/mii-exa-seltene-condition-sma-clinical*/.evidence[0].detail[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 236
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/Condition|4.0.1"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'http://omim.org' version '2024' could not be found, so the code cannot be validated. No versions of this code system are known"
            },
            "expression": [
              "Bundle/mii-exa-seltene-bundle-sma-complete: Bundle.entry[3].resource/*Condition/mii-exa-seltene-condition-sma-genetic*/.code.coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 236
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/Condition|4.0.1"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'http://snomed.info/sct' version 'null' could not be found, so the code cannot be validated. Valid versions: [http://snomed.info/sct/900000000000207008/version/20230731, http://snomed.info/sct/900000000000207008/version/20240101, http://snomed.info/sct/900000000000207008/version/20240701, http://snomed.info/sct/11000274103/version/20241115, http://snomed.info/sct/900000000000207008/version/20250101, http://snomed.info/sct/900000000000207008/version/20250701, http://snomed.info/sct/11000274103/version/20231115, http://snomed.info/sct/11010000107/version/20250921, http://snomed.info/sct/11000274103/version/20250515, http://snomed.info/sct/11000274103/version/20240515, http://snomed.info/sct/11000274103/version/20251115, http://snomed.info/sct/900000000000207008/version/20260101, http://snomed.info/sct/900000000000207008/version/20260701, http://snomed.info/sct/11000274103/version/20260515]"
            },
            "expression": [
              "Bundle/mii-exa-seltene-bundle-sma-complete: Bundle.entry[3].resource/*Condition/mii-exa-seltene-condition-sma-genetic*/.code.coding[1].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 236
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/Condition|4.0.1"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'http://www.orpha.net' version 'null' could not be found, so the code cannot be validated. Valid versions: [2023, 2024, 2025]"
            },
            "expression": [
              "Bundle/mii-exa-seltene-bundle-sma-complete: Bundle.entry[3].resource/*Condition/mii-exa-seltene-condition-sma-genetic*/.code.coding[2].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "BUNDLE_BUNDLE_POSSIBLE_MATCH_WRONG_FU"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/Condition|4.0.1"
              }
            ],
            "severity": "warning",
            "code": "required",
            "details": {
              "text": "Entry 0 matches the reference Patient/mii-exa-seltene-patient-sma-001 by type and id but its fullUrl urn:uuid:6830d99e-9bbe-48ed-8927-ff28eadc42e0 does not match the full target URL urn:uuid:mii-exa-seltene-patient-sma-001 by Bundle resolution rules"
            },
            "expression": [
              "Bundle/mii-exa-seltene-bundle-sma-complete: Bundle.entry[3].resource/*Condition/mii-exa-seltene-condition-sma-genetic*/.subject"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "BUNDLE_BUNDLE_POSSIBLE_MATCH_WRONG_FU"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/Condition|4.0.1"
              }
            ],
            "severity": "warning",
            "code": "required",
            "details": {
              "text": "Entry 6 matches the reference Observation/mii-exa-seltene-variant-smn1-001 by type and id but its fullUrl urn:uuid:89231fbc-2218-499e-b3f5-c11368975c6e does not match the full target URL urn:uuid:mii-exa-seltene-variant-smn1-001 by Bundle resolution rules"
            },
            "expression": [
              "Bundle/mii-exa-seltene-bundle-sma-complete: Bundle.entry[3].resource/*Condition/mii-exa-seltene-condition-sma-genetic*/.evidence[0].detail[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "BUNDLE_BUNDLE_POSSIBLE_MATCH_WRONG_FU"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/Condition|4.0.1"
              }
            ],
            "severity": "warning",
            "code": "required",
            "details": {
              "text": "Entry 7 matches the reference Observation/mii-exa-seltene-variant-smn2-001 by type and id but its fullUrl urn:uuid:3325c12d-0646-433e-8e46-042168eccf92 does not match the full target URL urn:uuid:mii-exa-seltene-variant-smn2-001 by Bundle resolution rules"
            },
            "expression": [
              "Bundle/mii-exa-seltene-bundle-sma-complete: Bundle.entry[3].resource/*Condition/mii-exa-seltene-condition-sma-genetic*/.evidence[0].detail[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "BUNDLE_BUNDLE_POSSIBLE_MATCH_WRONG_FU"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/FamilyMemberHistory|4.0.1"
              }
            ],
            "severity": "warning",
            "code": "required",
            "details": {
              "text": "Entry 0 matches the reference Patient/mii-exa-seltene-patient-sma-001 by type and id but its fullUrl urn:uuid:6830d99e-9bbe-48ed-8927-ff28eadc42e0 does not match the full target URL urn:uuid:mii-exa-seltene-patient-sma-001 by Bundle resolution rules"
            },
            "expression": [
              "Bundle/mii-exa-seltene-bundle-sma-complete: Bundle.entry[4].resource/*FamilyMemberHistory/mii-exa-seltene-family-history-001*/.patient"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 395
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "All_observations_should_have_a_performer"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Best Practice Recommendation: In general, all observations should have a performer"
            },
            "expression": [
              "Bundle/mii-exa-seltene-bundle-sma-complete: Bundle.entry[5].resource/*Observation/mii-exa-seltene-observation-sma-screening*/"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "BUNDLE_BUNDLE_POSSIBLE_MATCH_WRONG_FU"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/Observation|4.0.1"
              }
            ],
            "severity": "warning",
            "code": "required",
            "details": {
              "text": "Entry 0 matches the reference Patient/mii-exa-seltene-patient-sma-001 by type and id but its fullUrl urn:uuid:6830d99e-9bbe-48ed-8927-ff28eadc42e0 does not match the full target URL urn:uuid:mii-exa-seltene-patient-sma-001 by Bundle resolution rules"
            },
            "expression": [
              "Bundle/mii-exa-seltene-bundle-sma-complete: Bundle.entry[5].resource/*Observation/mii-exa-seltene-observation-sma-screening*/.subject"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 467
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 14
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Terminology_PassThrough_TX_Message"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/Observation|4.0.1"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "Resolved system http://unitsofmeasure.org (v3.0.1), but the definition doesn't include any codes, so the code has not been validated (for 'http://unitsofmeasure.org#1')"
            },
            "expression": [
              "Bundle/mii-exa-seltene-bundle-sma-complete: Bundle.entry[5].resource/*Observation/mii-exa-seltene-observation-sma-screening*/.component[1].value.ofType(Quantity)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 499
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "All_observations_should_have_a_performer"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Best Practice Recommendation: In general, all observations should have a performer"
            },
            "expression": [
              "Bundle/mii-exa-seltene-bundle-sma-complete: Bundle.entry[6].resource/*Observation/mii-exa-seltene-variant-smn1-001*/"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "BUNDLE_BUNDLE_POSSIBLE_MATCH_WRONG_FU"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/Observation|4.0.1"
              }
            ],
            "severity": "warning",
            "code": "required",
            "details": {
              "text": "Entry 0 matches the reference Patient/mii-exa-seltene-patient-sma-001 by type and id but its fullUrl urn:uuid:6830d99e-9bbe-48ed-8927-ff28eadc42e0 does not match the full target URL urn:uuid:mii-exa-seltene-patient-sma-001 by Bundle resolution rules"
            },
            "expression": [
              "Bundle/mii-exa-seltene-bundle-sma-complete: Bundle.entry[6].resource/*Observation/mii-exa-seltene-variant-smn1-001*/.subject"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 624
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "All_observations_should_have_a_performer"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Best Practice Recommendation: In general, all observations should have a performer"
            },
            "expression": [
              "Bundle/mii-exa-seltene-bundle-sma-complete: Bundle.entry[7].resource/*Observation/mii-exa-seltene-variant-smn2-001*/"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "BUNDLE_BUNDLE_POSSIBLE_MATCH_WRONG_FU"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/Observation|4.0.1"
              }
            ],
            "severity": "warning",
            "code": "required",
            "details": {
              "text": "Entry 0 matches the reference Patient/mii-exa-seltene-patient-sma-001 by type and id but its fullUrl urn:uuid:6830d99e-9bbe-48ed-8927-ff28eadc42e0 does not match the full target URL urn:uuid:mii-exa-seltene-patient-sma-001 by Bundle resolution rules"
            },
            "expression": [
              "Bundle/mii-exa-seltene-bundle-sma-complete: Bundle.entry[7].resource/*Observation/mii-exa-seltene-variant-smn2-001*/.subject"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "BUNDLE_BUNDLE_POSSIBLE_MATCH_WRONG_FU"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/Procedure|4.0.1"
              }
            ],
            "severity": "warning",
            "code": "required",
            "details": {
              "text": "Entry 0 matches the reference Patient/mii-exa-seltene-patient-sma-001 by type and id but its fullUrl urn:uuid:6830d99e-9bbe-48ed-8927-ff28eadc42e0 does not match the full target URL urn:uuid:mii-exa-seltene-patient-sma-001 by Bundle resolution rules"
            },
            "expression": [
              "Bundle/mii-exa-seltene-bundle-sma-complete: Bundle.entry[8].resource/*Procedure/mii-exa-seltene-procedure-gentherapy-001*/.subject"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "BUNDLE_BUNDLE_POSSIBLE_MATCH_WRONG_FU"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/Procedure|4.0.1"
              }
            ],
            "severity": "warning",
            "code": "required",
            "details": {
              "text": "Entry 3 matches the reference Condition/mii-exa-seltene-condition-sma-genetic by type and id but its fullUrl urn:uuid:9596df71-0f1b-495f-bf1c-16708dc952bf does not match the full target URL urn:uuid:mii-exa-seltene-condition-sma-genetic by Bundle resolution rules"
            },
            "expression": [
              "Bundle/mii-exa-seltene-bundle-sma-complete: Bundle.entry[8].resource/*Procedure/mii-exa-seltene-procedure-gentherapy-001*/.reasonReference[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 745
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "All_observations_should_have_a_performer"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Best Practice Recommendation: In general, all observations should have a performer"
            },
            "expression": [
              "Bundle/mii-exa-seltene-bundle-sma-complete: Bundle.entry[9].resource/*Observation/mii-exa-seltene-observation-alt-001*/"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "BUNDLE_BUNDLE_POSSIBLE_MATCH_WRONG_FU"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/Observation|4.0.1"
              }
            ],
            "severity": "warning",
            "code": "required",
            "details": {
              "text": "Entry 0 matches the reference Patient/mii-exa-seltene-patient-sma-001 by type and id but its fullUrl urn:uuid:6830d99e-9bbe-48ed-8927-ff28eadc42e0 does not match the full target URL urn:uuid:mii-exa-seltene-patient-sma-001 by Bundle resolution rules"
            },
            "expression": [
              "Bundle/mii-exa-seltene-bundle-sma-complete: Bundle.entry[9].resource/*Observation/mii-exa-seltene-observation-alt-001*/.subject"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 796
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "All_observations_should_have_a_performer"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Best Practice Recommendation: In general, all observations should have a performer"
            },
            "expression": [
              "Bundle/mii-exa-seltene-bundle-sma-complete: Bundle.entry[10].resource/*Observation/mii-exa-seltene-observation-ast-001*/"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "BUNDLE_BUNDLE_POSSIBLE_MATCH_WRONG_FU"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/Observation|4.0.1"
              }
            ],
            "severity": "warning",
            "code": "required",
            "details": {
              "text": "Entry 0 matches the reference Patient/mii-exa-seltene-patient-sma-001 by type and id but its fullUrl urn:uuid:6830d99e-9bbe-48ed-8927-ff28eadc42e0 does not match the full target URL urn:uuid:mii-exa-seltene-patient-sma-001 by Bundle resolution rules"
            },
            "expression": [
              "Bundle/mii-exa-seltene-bundle-sma-complete: Bundle.entry[10].resource/*Observation/mii-exa-seltene-observation-ast-001*/.subject"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 847
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "All_observations_should_have_a_performer"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Best Practice Recommendation: In general, all observations should have a performer"
            },
            "expression": [
              "Bundle/mii-exa-seltene-bundle-sma-complete: Bundle.entry[11].resource/*Observation/mii-exa-seltene-observation-plt-001*/"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "BUNDLE_BUNDLE_POSSIBLE_MATCH_WRONG_FU"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/Observation|4.0.1"
              }
            ],
            "severity": "warning",
            "code": "required",
            "details": {
              "text": "Entry 0 matches the reference Patient/mii-exa-seltene-patient-sma-001 by type and id but its fullUrl urn:uuid:6830d99e-9bbe-48ed-8927-ff28eadc42e0 does not match the full target URL urn:uuid:mii-exa-seltene-patient-sma-001 by Bundle resolution rules"
            },
            "expression": [
              "Bundle/mii-exa-seltene-bundle-sma-complete: Bundle.entry[11].resource/*Observation/mii-exa-seltene-observation-plt-001*/.subject"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 898
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "All_observations_should_have_a_performer"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Best Practice Recommendation: In general, all observations should have a performer"
            },
            "expression": [
              "Bundle/mii-exa-seltene-bundle-sma-complete: Bundle.entry[12].resource/*Observation/mii-exa-seltene-observation-troponin-001*/"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "BUNDLE_BUNDLE_POSSIBLE_MATCH_WRONG_FU"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/Observation|4.0.1"
              }
            ],
            "severity": "warning",
            "code": "required",
            "details": {
              "text": "Entry 0 matches the reference Patient/mii-exa-seltene-patient-sma-001 by type and id but its fullUrl urn:uuid:6830d99e-9bbe-48ed-8927-ff28eadc42e0 does not match the full target URL urn:uuid:mii-exa-seltene-patient-sma-001 by Bundle resolution rules"
            },
            "expression": [
              "Bundle/mii-exa-seltene-bundle-sma-complete: Bundle.entry[12].resource/*Observation/mii-exa-seltene-observation-troponin-001*/.subject"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 925
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Terminology_PassThrough_TX_Message"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/Observation|4.0.1"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "Resolved system http://unitsofmeasure.org (v3.0.1), but the definition doesn't include any codes, so the code has not been validated (for 'http://unitsofmeasure.org#ng/L')"
            },
            "expression": [
              "Bundle/mii-exa-seltene-bundle-sma-complete: Bundle.entry[12].resource/*Observation/mii-exa-seltene-observation-troponin-001*/.value.ofType(Quantity)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 950
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "All_observations_should_have_a_performer"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Best Practice Recommendation: In general, all observations should have a performer"
            },
            "expression": [
              "Bundle/mii-exa-seltene-bundle-sma-complete: Bundle.entry[13].resource/*Observation/mii-exa-seltene-observation-troponin-002*/"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "BUNDLE_BUNDLE_POSSIBLE_MATCH_WRONG_FU"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/Observation|4.0.1"
              }
            ],
            "severity": "warning",
            "code": "required",
            "details": {
              "text": "Entry 0 matches the reference Patient/mii-exa-seltene-patient-sma-001 by type and id but its fullUrl urn:uuid:6830d99e-9bbe-48ed-8927-ff28eadc42e0 does not match the full target URL urn:uuid:mii-exa-seltene-patient-sma-001 by Bundle resolution rules"
            },
            "expression": [
              "Bundle/mii-exa-seltene-bundle-sma-complete: Bundle.entry[13].resource/*Observation/mii-exa-seltene-observation-troponin-002*/.subject"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 977
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Terminology_PassThrough_TX_Message"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/Observation|4.0.1"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "Resolved system http://unitsofmeasure.org (v3.0.1), but the definition doesn't include any codes, so the code has not been validated (for 'http://unitsofmeasure.org#ng/L')"
            },
            "expression": [
              "Bundle/mii-exa-seltene-bundle-sma-complete: Bundle.entry[13].resource/*Observation/mii-exa-seltene-observation-troponin-002*/.value.ofType(Quantity)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1002
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "All_observations_should_have_a_performer"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Best Practice Recommendation: In general, all observations should have a performer"
            },
            "expression": [
              "Bundle/mii-exa-seltene-bundle-sma-complete: Bundle.entry[14].resource/*Observation/mii-exa-seltene-observation-troponin-003*/"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "BUNDLE_BUNDLE_POSSIBLE_MATCH_WRONG_FU"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/Observation|4.0.1"
              }
            ],
            "severity": "warning",
            "code": "required",
            "details": {
              "text": "Entry 0 matches the reference Patient/mii-exa-seltene-patient-sma-001 by type and id but its fullUrl urn:uuid:6830d99e-9bbe-48ed-8927-ff28eadc42e0 does not match the full target URL urn:uuid:mii-exa-seltene-patient-sma-001 by Bundle resolution rules"
            },
            "expression": [
              "Bundle/mii-exa-seltene-bundle-sma-complete: Bundle.entry[14].resource/*Observation/mii-exa-seltene-observation-troponin-003*/.subject"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1029
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Terminology_PassThrough_TX_Message"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/Observation|4.0.1"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "Resolved system http://unitsofmeasure.org (v3.0.1), but the definition doesn't include any codes, so the code has not been validated (for 'http://unitsofmeasure.org#ng/L')"
            },
            "expression": [
              "Bundle/mii-exa-seltene-bundle-sma-complete: Bundle.entry[14].resource/*Observation/mii-exa-seltene-observation-troponin-003*/.value.ofType(Quantity)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1054
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "All_observations_should_have_a_performer"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Best Practice Recommendation: In general, all observations should have a performer"
            },
            "expression": [
              "Bundle/mii-exa-seltene-bundle-sma-complete: Bundle.entry[15].resource/*Observation/mii-exa-seltene-observation-troponin-004*/"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "BUNDLE_BUNDLE_POSSIBLE_MATCH_WRONG_FU"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/Observation|4.0.1"
              }
            ],
            "severity": "warning",
            "code": "required",
            "details": {
              "text": "Entry 0 matches the reference Patient/mii-exa-seltene-patient-sma-001 by type and id but its fullUrl urn:uuid:6830d99e-9bbe-48ed-8927-ff28eadc42e0 does not match the full target URL urn:uuid:mii-exa-seltene-patient-sma-001 by Bundle resolution rules"
            },
            "expression": [
              "Bundle/mii-exa-seltene-bundle-sma-complete: Bundle.entry[15].resource/*Observation/mii-exa-seltene-observation-troponin-004*/.subject"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1081
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Terminology_PassThrough_TX_Message"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/Observation|4.0.1"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "Resolved system http://unitsofmeasure.org (v3.0.1), but the definition doesn't include any codes, so the code has not been validated (for 'http://unitsofmeasure.org#ng/L')"
            },
            "expression": [
              "Bundle/mii-exa-seltene-bundle-sma-complete: Bundle.entry[15].resource/*Observation/mii-exa-seltene-observation-troponin-004*/.value.ofType(Quantity)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "BUNDLE_BUNDLE_POSSIBLE_MATCH_WRONG_FU"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/ClinicalImpression|4.0.1"
              }
            ],
            "severity": "warning",
            "code": "required",
            "details": {
              "text": "Entry 0 matches the reference Patient/mii-exa-seltene-patient-sma-001 by type and id but its fullUrl urn:uuid:6830d99e-9bbe-48ed-8927-ff28eadc42e0 does not match the full target URL urn:uuid:mii-exa-seltene-patient-sma-001 by Bundle resolution rules"
            },
            "expression": [
              "Bundle/mii-exa-seltene-bundle-sma-complete: Bundle.entry[16].resource/*ClinicalImpression/mii-exa-seltene-clinical-impression-erstvorstellung*/.subject"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "BUNDLE_BUNDLE_POSSIBLE_MATCH_WRONG_FU"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/ClinicalImpression|4.0.1"
              }
            ],
            "severity": "warning",
            "code": "required",
            "details": {
              "text": "Entry 19 matches the reference Encounter/mii-exa-seltene-encounter-ambulant-001 by type and id but its fullUrl urn:uuid:98afd481-d1d6-4c2e-9d1c-51c651964e5f does not match the full target URL urn:uuid:mii-exa-seltene-encounter-ambulant-001 by Bundle resolution rules"
            },
            "expression": [
              "Bundle/mii-exa-seltene-bundle-sma-complete: Bundle.entry[16].resource/*ClinicalImpression/mii-exa-seltene-clinical-impression-erstvorstellung*/.encounter"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "BUNDLE_BUNDLE_POSSIBLE_MATCH_WRONG_FU"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/ClinicalImpression|4.0.1"
              }
            ],
            "severity": "warning",
            "code": "required",
            "details": {
              "text": "Entry 1 matches the reference Condition/mii-exa-seltene-condition-sma-suspected by type and id but its fullUrl urn:uuid:117180a6-0392-47c5-8841-aa5b57d0e47e does not match the full target URL urn:uuid:mii-exa-seltene-condition-sma-suspected by Bundle resolution rules"
            },
            "expression": [
              "Bundle/mii-exa-seltene-bundle-sma-complete: Bundle.entry[16].resource/*ClinicalImpression/mii-exa-seltene-clinical-impression-erstvorstellung*/.problem[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "BUNDLE_BUNDLE_POSSIBLE_MATCH_WRONG_FU"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/ClinicalImpression|4.0.1"
              }
            ],
            "severity": "warning",
            "code": "required",
            "details": {
              "text": "Entry 4 matches the reference FamilyMemberHistory/mii-exa-seltene-family-history-001 by type and id but its fullUrl urn:uuid:00e23000-f21c-470d-8f71-1942f0f72efe does not match the full target URL urn:uuid:mii-exa-seltene-family-history-001 by Bundle resolution rules"
            },
            "expression": [
              "Bundle/mii-exa-seltene-bundle-sma-complete: Bundle.entry[16].resource/*ClinicalImpression/mii-exa-seltene-clinical-impression-erstvorstellung*/.investigation[0].item[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "BUNDLE_BUNDLE_POSSIBLE_MATCH_WRONG_FU"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/ClinicalImpression|4.0.1"
              }
            ],
            "severity": "warning",
            "code": "required",
            "details": {
              "text": "Entry 12 matches the reference Observation/mii-exa-seltene-observation-troponin-001 by type and id but its fullUrl urn:uuid:ab5b69cf-4eae-4aa3-8ce4-5b5eb1a4a46a does not match the full target URL urn:uuid:mii-exa-seltene-observation-troponin-001 by Bundle resolution rules"
            },
            "expression": [
              "Bundle/mii-exa-seltene-bundle-sma-complete: Bundle.entry[16].resource/*ClinicalImpression/mii-exa-seltene-clinical-impression-erstvorstellung*/.investigation[1].item[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "BUNDLE_BUNDLE_POSSIBLE_MATCH_WRONG_FU"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/ClinicalImpression|4.0.1"
              }
            ],
            "severity": "warning",
            "code": "required",
            "details": {
              "text": "Entry 2 matches the reference Condition/mii-exa-seltene-condition-sma-clinical by type and id but its fullUrl urn:uuid:7041e5af-feab-4650-af1b-e2051ba0a95a does not match the full target URL urn:uuid:mii-exa-seltene-condition-sma-clinical by Bundle resolution rules"
            },
            "expression": [
              "Bundle/mii-exa-seltene-bundle-sma-complete: Bundle.entry[16].resource/*ClinicalImpression/mii-exa-seltene-clinical-impression-erstvorstellung*/.finding[0].itemReference"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "BUNDLE_BUNDLE_POSSIBLE_MATCH_WRONG_FU"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/ClinicalImpression|4.0.1"
              }
            ],
            "severity": "warning",
            "code": "required",
            "details": {
              "text": "Entry 3 matches the reference Condition/mii-exa-seltene-condition-sma-genetic by type and id but its fullUrl urn:uuid:9596df71-0f1b-495f-bf1c-16708dc952bf does not match the full target URL urn:uuid:mii-exa-seltene-condition-sma-genetic by Bundle resolution rules"
            },
            "expression": [
              "Bundle/mii-exa-seltene-bundle-sma-complete: Bundle.entry[16].resource/*ClinicalImpression/mii-exa-seltene-clinical-impression-erstvorstellung*/.finding[1].itemReference"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "BUNDLE_BUNDLE_POSSIBLE_MATCH_WRONG_FU"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/ClinicalImpression|4.0.1"
              }
            ],
            "severity": "warning",
            "code": "required",
            "details": {
              "text": "Entry 12 matches the reference Observation/mii-exa-seltene-observation-troponin-001 by type and id but its fullUrl urn:uuid:ab5b69cf-4eae-4aa3-8ce4-5b5eb1a4a46a does not match the full target URL urn:uuid:mii-exa-seltene-observation-troponin-001 by Bundle resolution rules"
            },
            "expression": [
              "Bundle/mii-exa-seltene-bundle-sma-complete: Bundle.entry[16].resource/*ClinicalImpression/mii-exa-seltene-clinical-impression-erstvorstellung*/.finding[2].itemReference"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "BUNDLE_BUNDLE_POSSIBLE_MATCH_WRONG_FU"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/ClinicalImpression|4.0.1"
              }
            ],
            "severity": "warning",
            "code": "required",
            "details": {
              "text": "Entry 0 matches the reference Patient/mii-exa-seltene-patient-sma-001 by type and id but its fullUrl urn:uuid:6830d99e-9bbe-48ed-8927-ff28eadc42e0 does not match the full target URL urn:uuid:mii-exa-seltene-patient-sma-001 by Bundle resolution rules"
            },
            "expression": [
              "Bundle/mii-exa-seltene-bundle-sma-complete: Bundle.entry[17].resource/*ClinicalImpression/mii-exa-seltene-clinical-impression-nachsorge*/.subject"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "BUNDLE_BUNDLE_POSSIBLE_MATCH_WRONG_FU"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/ClinicalImpression|4.0.1"
              }
            ],
            "severity": "warning",
            "code": "required",
            "details": {
              "text": "Entry 21 matches the reference Encounter/mii-exa-seltene-encounter-nachsorge-001 by type and id but its fullUrl urn:uuid:f8e29cb1-a8a9-4d56-ac0e-65fca096f860 does not match the full target URL urn:uuid:mii-exa-seltene-encounter-nachsorge-001 by Bundle resolution rules"
            },
            "expression": [
              "Bundle/mii-exa-seltene-bundle-sma-complete: Bundle.entry[17].resource/*ClinicalImpression/mii-exa-seltene-clinical-impression-nachsorge*/.encounter"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "BUNDLE_BUNDLE_POSSIBLE_MATCH_WRONG_FU"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/ClinicalImpression|4.0.1"
              }
            ],
            "severity": "warning",
            "code": "required",
            "details": {
              "text": "Entry 16 matches the reference ClinicalImpression/mii-exa-seltene-clinical-impression-erstvorstellung by type and id but its fullUrl urn:uuid:81c1e902-ea19-4d32-adbf-3ee234509cf6 does not match the full target URL urn:uuid:mii-exa-seltene-clinical-impression-erstvorstellung by Bundle resolution rules"
            },
            "expression": [
              "Bundle/mii-exa-seltene-bundle-sma-complete: Bundle.entry[17].resource/*ClinicalImpression/mii-exa-seltene-clinical-impression-nachsorge*/.previous"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "BUNDLE_BUNDLE_POSSIBLE_MATCH_WRONG_FU"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/ClinicalImpression|4.0.1"
              }
            ],
            "severity": "warning",
            "code": "required",
            "details": {
              "text": "Entry 2 matches the reference Condition/mii-exa-seltene-condition-sma-clinical by type and id but its fullUrl urn:uuid:7041e5af-feab-4650-af1b-e2051ba0a95a does not match the full target URL urn:uuid:mii-exa-seltene-condition-sma-clinical by Bundle resolution rules"
            },
            "expression": [
              "Bundle/mii-exa-seltene-bundle-sma-complete: Bundle.entry[17].resource/*ClinicalImpression/mii-exa-seltene-clinical-impression-nachsorge*/.problem[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "BUNDLE_BUNDLE_POSSIBLE_MATCH_WRONG_FU"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/ClinicalImpression|4.0.1"
              }
            ],
            "severity": "warning",
            "code": "required",
            "details": {
              "text": "Entry 3 matches the reference Condition/mii-exa-seltene-condition-sma-genetic by type and id but its fullUrl urn:uuid:9596df71-0f1b-495f-bf1c-16708dc952bf does not match the full target URL urn:uuid:mii-exa-seltene-condition-sma-genetic by Bundle resolution rules"
            },
            "expression": [
              "Bundle/mii-exa-seltene-bundle-sma-complete: Bundle.entry[17].resource/*ClinicalImpression/mii-exa-seltene-clinical-impression-nachsorge*/.problem[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "BUNDLE_BUNDLE_POSSIBLE_MATCH_WRONG_FU"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/ClinicalImpression|4.0.1"
              }
            ],
            "severity": "warning",
            "code": "required",
            "details": {
              "text": "Entry 15 matches the reference Observation/mii-exa-seltene-observation-troponin-004 by type and id but its fullUrl urn:uuid:0ccc9861-03d4-403b-a650-a9f24d64a615 does not match the full target URL urn:uuid:mii-exa-seltene-observation-troponin-004 by Bundle resolution rules"
            },
            "expression": [
              "Bundle/mii-exa-seltene-bundle-sma-complete: Bundle.entry[17].resource/*ClinicalImpression/mii-exa-seltene-clinical-impression-nachsorge*/.finding[0].itemReference"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "BUNDLE_BUNDLE_POSSIBLE_MATCH_WRONG_FU"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/Encounter|4.0.1"
              }
            ],
            "severity": "warning",
            "code": "required",
            "details": {
              "text": "Entry 0 matches the reference Patient/mii-exa-seltene-patient-sma-001 by type and id but its fullUrl urn:uuid:6830d99e-9bbe-48ed-8927-ff28eadc42e0 does not match the full target URL urn:uuid:mii-exa-seltene-patient-sma-001 by Bundle resolution rules"
            },
            "expression": [
              "Bundle/mii-exa-seltene-bundle-sma-complete: Bundle.entry[18].resource/*Encounter/mii-exa-seltene-encounter-screening-001*/.subject"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "BUNDLE_BUNDLE_POSSIBLE_MATCH_WRONG_FU"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/Encounter|4.0.1"
              }
            ],
            "severity": "warning",
            "code": "required",
            "details": {
              "text": "Entry 0 matches the reference Patient/mii-exa-seltene-patient-sma-001 by type and id but its fullUrl urn:uuid:6830d99e-9bbe-48ed-8927-ff28eadc42e0 does not match the full target URL urn:uuid:mii-exa-seltene-patient-sma-001 by Bundle resolution rules"
            },
            "expression": [
              "Bundle/mii-exa-seltene-bundle-sma-complete: Bundle.entry[19].resource/*Encounter/mii-exa-seltene-encounter-ambulant-001*/.subject"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "BUNDLE_BUNDLE_POSSIBLE_MATCH_WRONG_FU"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/Encounter|4.0.1"
              }
            ],
            "severity": "warning",
            "code": "required",
            "details": {
              "text": "Entry 2 matches the reference Condition/mii-exa-seltene-condition-sma-clinical by type and id but its fullUrl urn:uuid:7041e5af-feab-4650-af1b-e2051ba0a95a does not match the full target URL urn:uuid:mii-exa-seltene-condition-sma-clinical by Bundle resolution rules"
            },
            "expression": [
              "Bundle/mii-exa-seltene-bundle-sma-complete: Bundle.entry[19].resource/*Encounter/mii-exa-seltene-encounter-ambulant-001*/.diagnosis[0].condition"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "BUNDLE_BUNDLE_POSSIBLE_MATCH_WRONG_FU"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/Encounter|4.0.1"
              }
            ],
            "severity": "warning",
            "code": "required",
            "details": {
              "text": "Entry 0 matches the reference Patient/mii-exa-seltene-patient-sma-001 by type and id but its fullUrl urn:uuid:6830d99e-9bbe-48ed-8927-ff28eadc42e0 does not match the full target URL urn:uuid:mii-exa-seltene-patient-sma-001 by Bundle resolution rules"
            },
            "expression": [
              "Bundle/mii-exa-seltene-bundle-sma-complete: Bundle.entry[20].resource/*Encounter/mii-exa-seltene-encounter-stationaer-001*/.subject"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "BUNDLE_BUNDLE_POSSIBLE_MATCH_WRONG_FU"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/Encounter|4.0.1"
              }
            ],
            "severity": "warning",
            "code": "required",
            "details": {
              "text": "Entry 3 matches the reference Condition/mii-exa-seltene-condition-sma-genetic by type and id but its fullUrl urn:uuid:9596df71-0f1b-495f-bf1c-16708dc952bf does not match the full target URL urn:uuid:mii-exa-seltene-condition-sma-genetic by Bundle resolution rules"
            },
            "expression": [
              "Bundle/mii-exa-seltene-bundle-sma-complete: Bundle.entry[20].resource/*Encounter/mii-exa-seltene-encounter-stationaer-001*/.diagnosis[0].condition"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "BUNDLE_BUNDLE_POSSIBLE_MATCH_WRONG_FU"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/Encounter|4.0.1"
              }
            ],
            "severity": "warning",
            "code": "required",
            "details": {
              "text": "Entry 0 matches the reference Patient/mii-exa-seltene-patient-sma-001 by type and id but its fullUrl urn:uuid:6830d99e-9bbe-48ed-8927-ff28eadc42e0 does not match the full target URL urn:uuid:mii-exa-seltene-patient-sma-001 by Bundle resolution rules"
            },
            "expression": [
              "Bundle/mii-exa-seltene-bundle-sma-complete: Bundle.entry[21].resource/*Encounter/mii-exa-seltene-encounter-nachsorge-001*/.subject"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "BUNDLE_BUNDLE_POSSIBLE_MATCH_WRONG_FU"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/Encounter|4.0.1"
              }
            ],
            "severity": "warning",
            "code": "required",
            "details": {
              "text": "Entry 3 matches the reference Condition/mii-exa-seltene-condition-sma-genetic by type and id but its fullUrl urn:uuid:9596df71-0f1b-495f-bf1c-16708dc952bf does not match the full target URL urn:uuid:mii-exa-seltene-condition-sma-genetic by Bundle resolution rules"
            },
            "expression": [
              "Bundle/mii-exa-seltene-bundle-sma-complete: Bundle.entry[21].resource/*Encounter/mii-exa-seltene-encounter-nachsorge-001*/.diagnosis[0].condition"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/OperationOutcome/CapabilityStatement-mii-cps-seltene-capabilitystatement",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "CapabilityStatement-mii-cps-seltene-capabilitystatement",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 83600
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablecapabilitystatement|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "CapabilityStatement/mii-cps-seltene-capabilitystatement: CapabilityStatement.jurisdiction[0].coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 90497
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TYPE_SPECIFIC_CHECKS_DT_CANONICAL_RESOLVE"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablecapabilitystatement|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "A definition could not be found for Canonical URL 'https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/StructureDefinition/mii-pr-seltene-waist-to-hip-ratio'"
            },
            "expression": [
              "CapabilityStatement/mii-cps-seltene-capabilitystatement: CapabilityStatement.rest[0].resource[2].supportedProfile[3]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 115808
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TYPE_SPECIFIC_CHECKS_DT_CANONICAL_RESOLVE"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablecapabilitystatement|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "A definition could not be found for Canonical URL 'https://www.medizininformatik-initiative.de/fhir/modul-meta/SearchParameter/mii-sp-meta-familymemberhistory-Reasoncode'"
            },
            "expression": [
              "CapabilityStatement/mii-cps-seltene-capabilitystatement: CapabilityStatement.rest[0].resource[8].searchParam[10].definition"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/OperationOutcome/CarePlan-mii-exa-seltene-therapieplan",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "CarePlan-mii-exa-seltene-therapieplan"
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/OperationOutcome/ClinicalImpression-mii-exa-seltene-clinical-impression-erstvorstellung",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ClinicalImpression-mii-exa-seltene-clinical-impression-erstvorstellung"
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/OperationOutcome/ClinicalImpression-mii-exa-seltene-clinical-impression-nachsorge",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ClinicalImpression-mii-exa-seltene-clinical-impression-nachsorge"
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/OperationOutcome/ClinicalImpression-mii-exa-seltene-clinical-impression-seltene-assessment",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ClinicalImpression-mii-exa-seltene-clinical-impression-seltene-assessment"
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/OperationOutcome/CodeSystem-mii-cs-seltene-empfehlung-status-begruendung",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "CodeSystem-mii-cs-seltene-empfehlung-status-begruendung",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 6007
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablecodesystem|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "CodeSystem/mii-cs-seltene-empfehlung-status-begruendung: CodeSystem.jurisdiction[0].coding[0].system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/OperationOutcome/CodeSystem-mii-cs-seltene-hpo-change-status",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "CodeSystem-mii-cs-seltene-hpo-change-status",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 7788
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablecodesystem|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "CodeSystem/mii-cs-seltene-hpo-change-status: CodeSystem.jurisdiction[0].coding[0].system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/OperationOutcome/CodeSystem-mii-cs-seltene-icf-beurteilungsmerkmal",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "CodeSystem-mii-cs-seltene-icf-beurteilungsmerkmal",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 9425
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablecodesystem|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "CodeSystem/mii-cs-seltene-icf-beurteilungsmerkmal: CodeSystem.jurisdiction[0].coding[0].system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/OperationOutcome/CodeSystem-mii-cs-seltene-narse-therapietyp",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "CodeSystem-mii-cs-seltene-narse-therapietyp",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10483
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablecodesystem|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "CodeSystem/mii-cs-seltene-narse-therapietyp: CodeSystem.jurisdiction[0].coding[0].system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/OperationOutcome/CodeSystem-mii-cs-seltene-therapieempfehlung-strategie",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "CodeSystem-mii-cs-seltene-therapieempfehlung-strategie",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 9820
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablecodesystem|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "CodeSystem/mii-cs-seltene-therapieempfehlung-strategie: CodeSystem.jurisdiction[0].coding[0].system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/OperationOutcome/CodeSystem-mii-cs-seltene-therapieempfehlung-typ",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "CodeSystem-mii-cs-seltene-therapieempfehlung-typ",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 6437
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablecodesystem|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "CodeSystem/mii-cs-seltene-therapieempfehlung-typ: CodeSystem.jurisdiction[0].coding[0].system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/OperationOutcome/Condition-mii-exa-seltene-condition-cataract",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Condition-mii-exa-seltene-condition-cataract"
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/OperationOutcome/Condition-mii-exa-seltene-condition-marfan-clinical",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Condition-mii-exa-seltene-condition-marfan-clinical",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 9
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 4
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/StructureDefinition/mii-pr-seltene-clinical-diagnosis|2027.0.0-ballot"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'http://omim.org' version '2024' could not be found, so the code cannot be validated. No versions of this code system are known"
            },
            "expression": [
              "Condition/mii-exa-seltene-condition-marfan-clinical: Condition.code.coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 9
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 4
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/StructureDefinition/mii-pr-seltene-clinical-diagnosis|2027.0.0-ballot"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'http://snomed.info/sct' version 'null' could not be found, so the code cannot be validated. Valid versions: [http://snomed.info/sct/900000000000207008/version/20230731, http://snomed.info/sct/900000000000207008/version/20240101, http://snomed.info/sct/900000000000207008/version/20240701, http://snomed.info/sct/11000274103/version/20241115, http://snomed.info/sct/900000000000207008/version/20250101, http://snomed.info/sct/900000000000207008/version/20250701, http://snomed.info/sct/11000274103/version/20231115, http://snomed.info/sct/11010000107/version/20250921, http://snomed.info/sct/11000274103/version/20250515, http://snomed.info/sct/11000274103/version/20240515, http://snomed.info/sct/11000274103/version/20251115, http://snomed.info/sct/900000000000207008/version/20260101, http://snomed.info/sct/900000000000207008/version/20260701, http://snomed.info/sct/11000274103/version/20260515]"
            },
            "expression": [
              "Condition/mii-exa-seltene-condition-marfan-clinical: Condition.code.coding[1].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 9
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 4
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/StructureDefinition/mii-pr-seltene-clinical-diagnosis|2027.0.0-ballot"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'http://www.orpha.net' version 'null' could not be found, so the code cannot be validated. Valid versions: [2023, 2024, 2025]"
            },
            "expression": [
              "Condition/mii-exa-seltene-condition-marfan-clinical: Condition.code.coding[2].system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/OperationOutcome/Condition-mii-exa-seltene-condition-marfan-genetic",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Condition-mii-exa-seltene-condition-marfan-genetic",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 20
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 4
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/StructureDefinition/mii-pr-seltene-genetic-diagnosis|2027.0.0-ballot"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'http://omim.org' version '2024' could not be found, so the code cannot be validated. No versions of this code system are known"
            },
            "expression": [
              "Condition/mii-exa-seltene-condition-marfan-genetic: Condition.code.coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 20
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 4
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/StructureDefinition/mii-pr-seltene-genetic-diagnosis|2027.0.0-ballot"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'http://snomed.info/sct' version 'null' could not be found, so the code cannot be validated. Valid versions: [http://snomed.info/sct/900000000000207008/version/20230731, http://snomed.info/sct/900000000000207008/version/20240101, http://snomed.info/sct/900000000000207008/version/20240701, http://snomed.info/sct/11000274103/version/20241115, http://snomed.info/sct/900000000000207008/version/20250101, http://snomed.info/sct/900000000000207008/version/20250701, http://snomed.info/sct/11000274103/version/20231115, http://snomed.info/sct/11010000107/version/20250921, http://snomed.info/sct/11000274103/version/20250515, http://snomed.info/sct/11000274103/version/20240515, http://snomed.info/sct/11000274103/version/20251115, http://snomed.info/sct/900000000000207008/version/20260101, http://snomed.info/sct/900000000000207008/version/20260701, http://snomed.info/sct/11000274103/version/20260515]"
            },
            "expression": [
              "Condition/mii-exa-seltene-condition-marfan-genetic: Condition.code.coding[1].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 20
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 4
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/StructureDefinition/mii-pr-seltene-genetic-diagnosis|2027.0.0-ballot"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'http://www.orpha.net' version 'null' could not be found, so the code cannot be validated. Valid versions: [2023, 2024, 2025]"
            },
            "expression": [
              "Condition/mii-exa-seltene-condition-marfan-genetic: Condition.code.coding[2].system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/OperationOutcome/Condition-mii-exa-seltene-condition-marfan-suspected",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Condition-mii-exa-seltene-condition-marfan-suspected"
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/OperationOutcome/Condition-mii-exa-seltene-condition-pku-diagnosis",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Condition-mii-exa-seltene-condition-pku-diagnosis",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 20
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 4
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/StructureDefinition/mii-pr-seltene-genetic-diagnosis|2027.0.0-ballot"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'http://omim.org' version '2024' could not be found, so the code cannot be validated. No versions of this code system are known"
            },
            "expression": [
              "Condition/mii-exa-seltene-condition-pku-diagnosis: Condition.code.coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 20
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 4
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/StructureDefinition/mii-pr-seltene-genetic-diagnosis|2027.0.0-ballot"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'http://snomed.info/sct' version 'null' could not be found, so the code cannot be validated. Valid versions: [http://snomed.info/sct/900000000000207008/version/20230731, http://snomed.info/sct/900000000000207008/version/20240101, http://snomed.info/sct/900000000000207008/version/20240701, http://snomed.info/sct/11000274103/version/20241115, http://snomed.info/sct/900000000000207008/version/20250101, http://snomed.info/sct/900000000000207008/version/20250701, http://snomed.info/sct/11000274103/version/20231115, http://snomed.info/sct/11010000107/version/20250921, http://snomed.info/sct/11000274103/version/20250515, http://snomed.info/sct/11000274103/version/20240515, http://snomed.info/sct/11000274103/version/20251115, http://snomed.info/sct/900000000000207008/version/20260101, http://snomed.info/sct/900000000000207008/version/20260701, http://snomed.info/sct/11000274103/version/20260515]"
            },
            "expression": [
              "Condition/mii-exa-seltene-condition-pku-diagnosis: Condition.code.coding[1].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 20
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 4
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/StructureDefinition/mii-pr-seltene-genetic-diagnosis|2027.0.0-ballot"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'http://www.orpha.net' version 'null' could not be found, so the code cannot be validated. Valid versions: [2023, 2024, 2025]"
            },
            "expression": [
              "Condition/mii-exa-seltene-condition-pku-diagnosis: Condition.code.coding[2].system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/OperationOutcome/Condition-mii-exa-seltene-condition-sma-clinical",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Condition-mii-exa-seltene-condition-sma-clinical"
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/OperationOutcome/Condition-mii-exa-seltene-condition-sma-genetic",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Condition-mii-exa-seltene-condition-sma-genetic",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 20
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 4
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/StructureDefinition/mii-pr-seltene-genetic-diagnosis|2027.0.0-ballot"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'http://omim.org' version '2024' could not be found, so the code cannot be validated. No versions of this code system are known"
            },
            "expression": [
              "Condition/mii-exa-seltene-condition-sma-genetic: Condition.code.coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 20
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 4
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/StructureDefinition/mii-pr-seltene-genetic-diagnosis|2027.0.0-ballot"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'http://snomed.info/sct' version 'null' could not be found, so the code cannot be validated. Valid versions: [http://snomed.info/sct/900000000000207008/version/20230731, http://snomed.info/sct/900000000000207008/version/20240101, http://snomed.info/sct/900000000000207008/version/20240701, http://snomed.info/sct/11000274103/version/20241115, http://snomed.info/sct/900000000000207008/version/20250101, http://snomed.info/sct/900000000000207008/version/20250701, http://snomed.info/sct/11000274103/version/20231115, http://snomed.info/sct/11010000107/version/20250921, http://snomed.info/sct/11000274103/version/20250515, http://snomed.info/sct/11000274103/version/20240515, http://snomed.info/sct/11000274103/version/20251115, http://snomed.info/sct/900000000000207008/version/20260101, http://snomed.info/sct/900000000000207008/version/20260701, http://snomed.info/sct/11000274103/version/20260515]"
            },
            "expression": [
              "Condition/mii-exa-seltene-condition-sma-genetic: Condition.code.coding[1].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 20
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 4
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/StructureDefinition/mii-pr-seltene-genetic-diagnosis|2027.0.0-ballot"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'http://www.orpha.net' version 'null' could not be found, so the code cannot be validated. Valid versions: [2023, 2024, 2025]"
            },
            "expression": [
              "Condition/mii-exa-seltene-condition-sma-genetic: Condition.code.coding[2].system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/OperationOutcome/Condition-mii-exa-seltene-condition-sma-suspected",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Condition-mii-exa-seltene-condition-sma-suspected"
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/OperationOutcome/Condition-mii-exa-seltene-example-brca1-genetic-diagnosis",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Condition-mii-exa-seltene-example-brca1-genetic-diagnosis",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 20
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 4
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/StructureDefinition/mii-pr-seltene-genetic-diagnosis|2027.0.0-ballot"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'http://omim.org' version '2024' could not be found, so the code cannot be validated. No versions of this code system are known"
            },
            "expression": [
              "Condition/mii-exa-seltene-example-brca1-genetic-diagnosis: Condition.code.coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 20
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 4
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/StructureDefinition/mii-pr-seltene-genetic-diagnosis|2027.0.0-ballot"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'http://snomed.info/sct' version 'null' could not be found, so the code cannot be validated. Valid versions: [http://snomed.info/sct/900000000000207008/version/20230731, http://snomed.info/sct/900000000000207008/version/20240101, http://snomed.info/sct/900000000000207008/version/20240701, http://snomed.info/sct/11000274103/version/20241115, http://snomed.info/sct/900000000000207008/version/20250101, http://snomed.info/sct/900000000000207008/version/20250701, http://snomed.info/sct/11000274103/version/20231115, http://snomed.info/sct/11010000107/version/20250921, http://snomed.info/sct/11000274103/version/20250515, http://snomed.info/sct/11000274103/version/20240515, http://snomed.info/sct/11000274103/version/20251115, http://snomed.info/sct/900000000000207008/version/20260101, http://snomed.info/sct/900000000000207008/version/20260701, http://snomed.info/sct/11000274103/version/20260515]"
            },
            "expression": [
              "Condition/mii-exa-seltene-example-brca1-genetic-diagnosis: Condition.code.coding[1].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 20
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 4
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/StructureDefinition/mii-pr-seltene-genetic-diagnosis|2027.0.0-ballot"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'http://www.orpha.net' version 'null' could not be found, so the code cannot be validated. Valid versions: [2023, 2024, 2025]"
            },
            "expression": [
              "Condition/mii-exa-seltene-example-brca1-genetic-diagnosis: Condition.code.coding[2].system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/OperationOutcome/Condition-mii-exa-seltene-example-cf-clinical",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Condition-mii-exa-seltene-example-cf-clinical",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 9
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 4
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/StructureDefinition/mii-pr-seltene-clinical-diagnosis|2027.0.0-ballot"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'http://omim.org' version '2024' could not be found, so the code cannot be validated. No versions of this code system are known"
            },
            "expression": [
              "Condition/mii-exa-seltene-example-cf-clinical: Condition.code.coding[0].system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/OperationOutcome/Condition-mii-exa-seltene-example-cf-excluded-after-screening",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Condition-mii-exa-seltene-example-cf-excluded-after-screening",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 20
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 4
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/StructureDefinition/mii-pr-seltene-genetic-diagnosis|2027.0.0-ballot"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'http://omim.org' version '2024' could not be found, so the code cannot be validated. No versions of this code system are known"
            },
            "expression": [
              "Condition/mii-exa-seltene-example-cf-excluded-after-screening: Condition.code.coding[0].system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/OperationOutcome/Condition-mii-exa-seltene-example-cf-genetic",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Condition-mii-exa-seltene-example-cf-genetic",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 20
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 4
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/StructureDefinition/mii-pr-seltene-genetic-diagnosis|2027.0.0-ballot"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'http://omim.org' version '2024' could not be found, so the code cannot be validated. No versions of this code system are known"
            },
            "expression": [
              "Condition/mii-exa-seltene-example-cf-genetic: Condition.code.coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 20
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 4
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/StructureDefinition/mii-pr-seltene-genetic-diagnosis|2027.0.0-ballot"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'http://snomed.info/sct' version 'null' could not be found, so the code cannot be validated. Valid versions: [http://snomed.info/sct/900000000000207008/version/20230731, http://snomed.info/sct/900000000000207008/version/20240101, http://snomed.info/sct/900000000000207008/version/20240701, http://snomed.info/sct/11000274103/version/20241115, http://snomed.info/sct/900000000000207008/version/20250101, http://snomed.info/sct/900000000000207008/version/20250701, http://snomed.info/sct/11000274103/version/20231115, http://snomed.info/sct/11010000107/version/20250921, http://snomed.info/sct/11000274103/version/20250515, http://snomed.info/sct/11000274103/version/20240515, http://snomed.info/sct/11000274103/version/20251115, http://snomed.info/sct/900000000000207008/version/20260101, http://snomed.info/sct/900000000000207008/version/20260701, http://snomed.info/sct/11000274103/version/20260515]"
            },
            "expression": [
              "Condition/mii-exa-seltene-example-cf-genetic: Condition.code.coding[1].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 20
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 4
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/StructureDefinition/mii-pr-seltene-genetic-diagnosis|2027.0.0-ballot"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'http://www.orpha.net' version 'null' could not be found, so the code cannot be validated. Valid versions: [2023, 2024, 2025]"
            },
            "expression": [
              "Condition/mii-exa-seltene-example-cf-genetic: Condition.code.coding[2].system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/OperationOutcome/Condition-mii-exa-seltene-example-dmd-excluded-bmd-confirmed",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Condition-mii-exa-seltene-example-dmd-excluded-bmd-confirmed",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 20
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 4
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/StructureDefinition/mii-pr-seltene-genetic-diagnosis|2027.0.0-ballot"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'http://omim.org' version '2024' could not be found, so the code cannot be validated. No versions of this code system are known"
            },
            "expression": [
              "Condition/mii-exa-seltene-example-dmd-excluded-bmd-confirmed: Condition.code.coding[0].system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/OperationOutcome/Condition-mii-exa-seltene-example-dmd-genetic-diagnosis",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Condition-mii-exa-seltene-example-dmd-genetic-diagnosis",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 20
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 4
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/StructureDefinition/mii-pr-seltene-genetic-diagnosis|2027.0.0-ballot"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'http://omim.org' version '2024' could not be found, so the code cannot be validated. No versions of this code system are known"
            },
            "expression": [
              "Condition/mii-exa-seltene-example-dmd-genetic-diagnosis: Condition.code.coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 20
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 4
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/StructureDefinition/mii-pr-seltene-genetic-diagnosis|2027.0.0-ballot"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'http://snomed.info/sct' version 'null' could not be found, so the code cannot be validated. Valid versions: [http://snomed.info/sct/900000000000207008/version/20230731, http://snomed.info/sct/900000000000207008/version/20240101, http://snomed.info/sct/900000000000207008/version/20240701, http://snomed.info/sct/11000274103/version/20241115, http://snomed.info/sct/900000000000207008/version/20250101, http://snomed.info/sct/900000000000207008/version/20250701, http://snomed.info/sct/11000274103/version/20231115, http://snomed.info/sct/11010000107/version/20250921, http://snomed.info/sct/11000274103/version/20250515, http://snomed.info/sct/11000274103/version/20240515, http://snomed.info/sct/11000274103/version/20251115, http://snomed.info/sct/900000000000207008/version/20260101, http://snomed.info/sct/900000000000207008/version/20260701, http://snomed.info/sct/11000274103/version/20260515]"
            },
            "expression": [
              "Condition/mii-exa-seltene-example-dmd-genetic-diagnosis: Condition.code.coding[1].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 20
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 4
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/StructureDefinition/mii-pr-seltene-genetic-diagnosis|2027.0.0-ballot"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'http://www.orpha.net' version 'null' could not be found, so the code cannot be validated. Valid versions: [2023, 2024, 2025]"
            },
            "expression": [
              "Condition/mii-exa-seltene-example-dmd-genetic-diagnosis: Condition.code.coding[2].system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/OperationOutcome/Condition-mii-exa-seltene-example-eds-excluded-clinical",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Condition-mii-exa-seltene-example-eds-excluded-clinical"
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/OperationOutcome/Condition-mii-exa-seltene-example-marfan-clinical-diagnosis",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Condition-mii-exa-seltene-example-marfan-clinical-diagnosis",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 9
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 4
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/StructureDefinition/mii-pr-seltene-clinical-diagnosis|2027.0.0-ballot"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'http://omim.org' version '2024' could not be found, so the code cannot be validated. No versions of this code system are known"
            },
            "expression": [
              "Condition/mii-exa-seltene-example-marfan-clinical-diagnosis: Condition.code.coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 9
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 4
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/StructureDefinition/mii-pr-seltene-clinical-diagnosis|2027.0.0-ballot"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'http://snomed.info/sct' version 'null' could not be found, so the code cannot be validated. Valid versions: [http://snomed.info/sct/900000000000207008/version/20230731, http://snomed.info/sct/900000000000207008/version/20240101, http://snomed.info/sct/900000000000207008/version/20240701, http://snomed.info/sct/11000274103/version/20241115, http://snomed.info/sct/900000000000207008/version/20250101, http://snomed.info/sct/900000000000207008/version/20250701, http://snomed.info/sct/11000274103/version/20231115, http://snomed.info/sct/11010000107/version/20250921, http://snomed.info/sct/11000274103/version/20250515, http://snomed.info/sct/11000274103/version/20240515, http://snomed.info/sct/11000274103/version/20251115, http://snomed.info/sct/900000000000207008/version/20260101, http://snomed.info/sct/900000000000207008/version/20260701, http://snomed.info/sct/11000274103/version/20260515]"
            },
            "expression": [
              "Condition/mii-exa-seltene-example-marfan-clinical-diagnosis: Condition.code.coding[1].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 9
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 4
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/StructureDefinition/mii-pr-seltene-clinical-diagnosis|2027.0.0-ballot"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'http://www.orpha.net' version 'null' could not be found, so the code cannot be validated. Valid versions: [2023, 2024, 2025]"
            },
            "expression": [
              "Condition/mii-exa-seltene-example-marfan-clinical-diagnosis: Condition.code.coding[2].system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/OperationOutcome/Condition-mii-exa-seltene-example-marfan-excluded-clinical",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Condition-mii-exa-seltene-example-marfan-excluded-clinical",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 9
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 4
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/StructureDefinition/mii-pr-seltene-clinical-diagnosis|2027.0.0-ballot"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'http://omim.org' version '2024' could not be found, so the code cannot be validated. No versions of this code system are known"
            },
            "expression": [
              "Condition/mii-exa-seltene-example-marfan-excluded-clinical: Condition.code.coding[0].system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/OperationOutcome/Condition-mii-exa-seltene-example-metabolic-myopathy-excluded",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Condition-mii-exa-seltene-example-metabolic-myopathy-excluded"
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/OperationOutcome/Condition-mii-exa-seltene-example-noonan-clinical-diagnosis",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Condition-mii-exa-seltene-example-noonan-clinical-diagnosis"
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/OperationOutcome/Condition-mii-exa-seltene-example-sma-excluded-genetic",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Condition-mii-exa-seltene-example-sma-excluded-genetic",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 20
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 4
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/StructureDefinition/mii-pr-seltene-genetic-diagnosis|2027.0.0-ballot"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'http://omim.org' could not be found, so the code cannot be validated"
            },
            "expression": [
              "Condition/mii-exa-seltene-example-sma-excluded-genetic: Condition.code.coding[0].system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/OperationOutcome/Condition-mii-exa-seltene-example-sma-genetic-diagnosis",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Condition-mii-exa-seltene-example-sma-genetic-diagnosis",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 20
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 4
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/StructureDefinition/mii-pr-seltene-genetic-diagnosis|2027.0.0-ballot"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'http://omim.org' version '2024' could not be found, so the code cannot be validated. No versions of this code system are known"
            },
            "expression": [
              "Condition/mii-exa-seltene-example-sma-genetic-diagnosis: Condition.code.coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 20
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 4
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/StructureDefinition/mii-pr-seltene-genetic-diagnosis|2027.0.0-ballot"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'http://snomed.info/sct' version 'null' could not be found, so the code cannot be validated. Valid versions: [http://snomed.info/sct/900000000000207008/version/20230731, http://snomed.info/sct/900000000000207008/version/20240101, http://snomed.info/sct/900000000000207008/version/20240701, http://snomed.info/sct/11000274103/version/20241115, http://snomed.info/sct/900000000000207008/version/20250101, http://snomed.info/sct/900000000000207008/version/20250701, http://snomed.info/sct/11000274103/version/20231115, http://snomed.info/sct/11010000107/version/20250921, http://snomed.info/sct/11000274103/version/20250515, http://snomed.info/sct/11000274103/version/20240515, http://snomed.info/sct/11000274103/version/20251115, http://snomed.info/sct/900000000000207008/version/20260101, http://snomed.info/sct/900000000000207008/version/20260701, http://snomed.info/sct/11000274103/version/20260515]"
            },
            "expression": [
              "Condition/mii-exa-seltene-example-sma-genetic-diagnosis: Condition.code.coding[1].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 20
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 4
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/StructureDefinition/mii-pr-seltene-genetic-diagnosis|2027.0.0-ballot"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'http://www.orpha.net' version 'null' could not be found, so the code cannot be validated. Valid versions: [2023, 2024, 2025]"
            },
            "expression": [
              "Condition/mii-exa-seltene-example-sma-genetic-diagnosis: Condition.code.coding[2].system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/OperationOutcome/Condition-mii-exa-seltene-symptom-condition",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Condition-mii-exa-seltene-symptom-condition"
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/OperationOutcome/Consent-mii-exa-seltene-register-einwilligung",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Consent-mii-exa-seltene-register-einwilligung"
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/OperationOutcome/DiagnosticReport-mii-exa-seltene-molgen-brca-panel",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "DiagnosticReport-mii-exa-seltene-molgen-brca-panel",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 36
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 6
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/DiagnosticReport|4.0.1"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'http://omim.org' could not be found, so the code cannot be validated"
            },
            "expression": [
              "DiagnosticReport/mii-exa-seltene-molgen-brca-panel: DiagnosticReport.conclusionCode[0].coding[0]"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/OperationOutcome/DiagnosticReport-mii-exa-seltene-molgen-cf-diagnostic",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "DiagnosticReport-mii-exa-seltene-molgen-cf-diagnostic",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 36
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 6
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/DiagnosticReport|4.0.1"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'http://omim.org' could not be found, so the code cannot be validated"
            },
            "expression": [
              "DiagnosticReport/mii-exa-seltene-molgen-cf-diagnostic: DiagnosticReport.conclusionCode[0].coding[0]"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/OperationOutcome/DiagnosticReport-mii-exa-seltene-molgen-diagnostic-dmd-duchenne",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "DiagnosticReport-mii-exa-seltene-molgen-diagnostic-dmd-duchenne",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 36
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 6
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/DiagnosticReport|4.0.1"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'http://omim.org' could not be found, so the code cannot be validated"
            },
            "expression": [
              "DiagnosticReport/mii-exa-seltene-molgen-diagnostic-dmd-duchenne: DiagnosticReport.conclusionCode[0].coding[0]"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/OperationOutcome/DiagnosticReport-mii-exa-seltene-molgen-diagnostic-dmd",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "DiagnosticReport-mii-exa-seltene-molgen-diagnostic-dmd",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 36
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 6
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/DiagnosticReport|4.0.1"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'http://omim.org' could not be found, so the code cannot be validated"
            },
            "expression": [
              "DiagnosticReport/mii-exa-seltene-molgen-diagnostic-dmd: DiagnosticReport.conclusionCode[0].coding[0]"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/OperationOutcome/DiagnosticReport-mii-exa-seltene-molgen-diagnostic-implication-sma",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "DiagnosticReport-mii-exa-seltene-molgen-diagnostic-implication-sma",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 36
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 6
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/DiagnosticReport|4.0.1"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'http://omim.org' could not be found, so the code cannot be validated"
            },
            "expression": [
              "DiagnosticReport/mii-exa-seltene-molgen-diagnostic-implication-sma: DiagnosticReport.conclusionCode[0].coding[0]"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/OperationOutcome/DiagnosticReport-mii-exa-seltene-molgen-sma-negative",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "DiagnosticReport-mii-exa-seltene-molgen-sma-negative"
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/OperationOutcome/DiagnosticReport-mii-exa-seltene-muscle-biopsy-normal",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "DiagnosticReport-mii-exa-seltene-muscle-biopsy-normal"
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/OperationOutcome/Encounter-mii-exa-seltene-encounter-ambulant-001",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Encounter-mii-exa-seltene-encounter-ambulant-001"
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/OperationOutcome/Encounter-mii-exa-seltene-encounter-cardiology-consultation",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Encounter-mii-exa-seltene-encounter-cardiology-consultation"
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/OperationOutcome/Encounter-mii-exa-seltene-encounter-cardiology",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Encounter-mii-exa-seltene-encounter-cardiology"
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/OperationOutcome/Encounter-mii-exa-seltene-encounter-cataract-surgery",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Encounter-mii-exa-seltene-encounter-cataract-surgery"
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/OperationOutcome/Encounter-mii-exa-seltene-encounter-genetic-consultation",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Encounter-mii-exa-seltene-encounter-genetic-consultation"
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/OperationOutcome/Encounter-mii-exa-seltene-encounter-nachsorge-001",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Encounter-mii-exa-seltene-encounter-nachsorge-001"
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/OperationOutcome/Encounter-mii-exa-seltene-encounter-ophthalmology",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Encounter-mii-exa-seltene-encounter-ophthalmology"
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/OperationOutcome/Encounter-mii-exa-seltene-encounter-screening-001",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Encounter-mii-exa-seltene-encounter-screening-001"
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/OperationOutcome/Encounter-mii-exa-seltene-encounter-stationaer-001",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Encounter-mii-exa-seltene-encounter-stationaer-001"
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/OperationOutcome/Encounter-mii-exa-seltene-encounter-surgery-planned",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Encounter-mii-exa-seltene-encounter-surgery-planned"
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/OperationOutcome/FamilyMemberHistory-mii-exa-seltene-familienanamnese",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "FamilyMemberHistory-mii-exa-seltene-familienanamnese",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 46
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 4
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Coding_has_no_system__cannot_validate"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/StructureDefinition/mii-pr-seltene-familienanamnese|2027.0.0-ballot"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Coding has no system. A code with no system has no defined meaning, and it cannot be validated. A system should be provided"
            },
            "expression": [
              "FamilyMemberHistory/mii-exa-seltene-familienanamnese: FamilyMemberHistory.sex.coding[0]"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/OperationOutcome/FamilyMemberHistory-mii-exa-seltene-family-history-001",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "FamilyMemberHistory-mii-exa-seltene-family-history-001"
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/OperationOutcome/Library-mii-exa-seltene-register-katalog-euro-nmd",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Library-mii-exa-seltene-register-katalog-euro-nmd",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 268
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/Library|4.0.1"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://ern-euro-nmd.eu/fhir/sid/registry'"
            },
            "expression": [
              "Library/mii-exa-seltene-register-katalog-euro-nmd: Library.identifier[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 843
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/Library|4.0.1"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "Library/mii-exa-seltene-register-katalog-euro-nmd: Library.jurisdiction[0].coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 929
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/Library|4.0.1"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://ern-euro-nmd.eu/registry/'"
            },
            "expression": [
              "Library/mii-exa-seltene-register-katalog-euro-nmd: Library.relatedArtifact[0].url"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "Publisher"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "\"The narrative includes custom content for the default language (en), but does not include translated content for the de language, so the default language has been used"
            },
            "expression": [
              "IG"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/OperationOutcome/MedicationRequest-mii-exa-seltene-therapieempfehlung-gentherapie-sma",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "MedicationRequest-mii-exa-seltene-therapieempfehlung-gentherapie-sma"
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/OperationOutcome/MedicationRequest-mii-exa-seltene-therapieempfehlung-losartan-marfan",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "MedicationRequest-mii-exa-seltene-therapieempfehlung-losartan-marfan",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 33
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/StructureDefinition/mii-pr-seltene-therapieempfehlung|2027.0.0-ballot"
              }
            ],
            "severity": "warning",
            "code": "informational",
            "details": {
              "text": "Got multiple matches for ''http://fhir.de/CodeSystem/bfarm/atc#C09CA01 ('Losartan')'' in ValueSet."
            },
            "expression": [
              "MedicationRequest/mii-exa-seltene-therapieempfehlung-losartan-marfan: MedicationRequest.medication.ofType(CodeableConcept).coding[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 33
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/StructureDefinition/mii-pr-seltene-therapieempfehlung|2027.0.0-ballot"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "Got multiple matches for ''http://fhir.de/CodeSystem/bfarm/atc#C09CA01 ('Losartan')'' in ValueSet."
            },
            "expression": [
              "MedicationRequest/mii-exa-seltene-therapieempfehlung-losartan-marfan: MedicationRequest.medication.ofType(CodeableConcept).coding[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 50
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 28
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/StructureDefinition/mii-pr-seltene-therapieempfehlung|2027.0.0-ballot"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "A definition for CodeSystem 'null' could not be found, so the code cannot be validated"
            },
            "expression": [
              "MedicationRequest/mii-exa-seltene-therapieempfehlung-losartan-marfan: MedicationRequest.dosageInstruction[0].timing.repeat.periodUnit"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 55
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 12
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/StructureDefinition/mii-pr-seltene-therapieempfehlung|2027.0.0-ballot"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "Resolved system http://unitsofmeasure.org (v3.0.1), but the definition doesn't include any codes, so the code has not been validated"
            },
            "expression": [
              "MedicationRequest/mii-exa-seltene-therapieempfehlung-losartan-marfan: MedicationRequest.dosageInstruction[0].doseAndRate[0].dose.ofType(Quantity)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 55
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 12
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Terminology_PassThrough_TX_Message"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/StructureDefinition/mii-pr-seltene-therapieempfehlung|2027.0.0-ballot"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "Resolved system http://unitsofmeasure.org (v3.0.1), but the definition doesn't include any codes, so the code has not been validated (for 'http://unitsofmeasure.org#mg')"
            },
            "expression": [
              "MedicationRequest/mii-exa-seltene-therapieempfehlung-losartan-marfan: MedicationRequest.dosageInstruction[0].doseAndRate[0].dose.ofType(Quantity)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 44
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 6
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://ig.fhir.de/igs/medication/StructureDefinition/DosageDE#DosageStructuredOrFreeTextWarning"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/StructureDefinition/mii-pr-seltene-therapieempfehlung|2027.0.0-ballot"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: DosageStructuredOrFreeTextWarning: 'Die Dosierungsangabe darf entweder nur als Freitext oder nur als vollständige strukturierte Information erfolgen — eine Mischung ist nicht erlaubt. ((%resource.ofType(MedicationRequest).dosageInstruction | \n %resource.ofType(MedicationDispense).dosageInstruction | \n %resource.ofType(MedicationStatement).dosage).all(\n  (text.exists() and timing.empty() and doseAndRate.empty()) or\n  (text.empty() and (timing.exists() or doseAndRate.exists()))\n))' (defined in http://ig.fhir.de/igs/medication/StructureDefinition/DosageDE)"
            },
            "expression": [
              "MedicationRequest/mii-exa-seltene-therapieempfehlung-losartan-marfan: MedicationRequest.dosageInstruction[0]"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/OperationOutcome/MedicationStatement-mii-exa-seltene-medication-losartan",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "MedicationStatement-mii-exa-seltene-medication-losartan",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 55
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 28
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/MedicationStatement|4.0.1"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "A definition for CodeSystem 'null' could not be found, so the code cannot be validated"
            },
            "expression": [
              "MedicationStatement/mii-exa-seltene-medication-losartan: MedicationStatement.dosage[0].timing.repeat.periodUnit"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 43
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 12
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Terminology_PassThrough_TX_Message"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/MedicationStatement|4.0.1"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "Resolved system http://unitsofmeasure.org (v3.0.1), but the definition doesn't include any codes, so the code has not been validated (for 'http://unitsofmeasure.org#mg')"
            },
            "expression": [
              "MedicationStatement/mii-exa-seltene-medication-losartan: MedicationStatement.dosage[0].doseAndRate[0].dose.ofType(Quantity)"
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          }
        ]
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    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/OperationOutcome/Observation-mii-exa-seltene-anteverted-nares",
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        "resourceType": "OperationOutcome",
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          {
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                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "All_observations_should_have_a_performer"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Best Practice Recommendation: In general, all observations should have a performer"
            },
            "expression": [
              "Observation/mii-exa-seltene-anteverted-nares: Observation"
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          }
        ]
      }
    },
    {
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        "resourceType": "OperationOutcome",
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              {
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              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "All_observations_should_have_a_performer"
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            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Best Practice Recommendation: In general, all observations should have a performer"
            },
            "expression": [
              "Observation/mii-exa-seltene-aortic-root-dilatation: Observation"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/OperationOutcome/Observation-mii-exa-seltene-aortic-root-normal",
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        "resourceType": "OperationOutcome",
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
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            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "Resolved system http://unitsofmeasure.org (v3.0.1), but the definition doesn't include any codes, so the code has not been validated (for 'http://unitsofmeasure.org#mm')"
            },
            "expression": [
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                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
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                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
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            ],
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            "code": "invalid",
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              "text": "Best Practice Recommendation: In general, all observations should have a performer"
            },
            "expression": [
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          }
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    },
    {
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        "resourceType": "OperationOutcome",
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              {
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
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            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Best Practice Recommendation: In general, all observations should have a performer"
            },
            "expression": [
              "Observation/mii-exa-seltene-arachnodactyly: Observation"
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          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/OperationOutcome/Observation-mii-exa-seltene-beighton-score-low",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Observation-mii-exa-seltene-beighton-score-low",
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            "extension": [
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                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
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              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "All_observations_should_have_a_performer"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Best Practice Recommendation: In general, all observations should have a performer"
            },
            "expression": [
              "Observation/mii-exa-seltene-beighton-score-low: Observation"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/OperationOutcome/Observation-mii-exa-seltene-bodymassindex",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Observation-mii-exa-seltene-bodymassindex",
        "issue": [
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
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              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Terminology_PassThrough_TX_Message"
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
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            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "Resolved system http://unitsofmeasure.org (v3.0.1), but the definition doesn't include any codes, so the code has not been validated (for 'http://unitsofmeasure.org#kg/m2')"
            },
            "expression": [
              "Observation/mii-exa-seltene-bodymassindex: Observation.value.ofType(Quantity)"
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          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 2
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "All_observations_should_have_a_performer"
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            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Best Practice Recommendation: In general, all observations should have a performer"
            },
            "expression": [
              "Observation/mii-exa-seltene-bodymassindex: Observation"
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          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/OperationOutcome/Observation-mii-exa-seltene-chronic-diarrhea",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Observation-mii-exa-seltene-chronic-diarrhea",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 2
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "All_observations_should_have_a_performer"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Best Practice Recommendation: In general, all observations should have a performer"
            },
            "expression": [
              "Observation/mii-exa-seltene-chronic-diarrhea: Observation"
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          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/OperationOutcome/Observation-mii-exa-seltene-consanguinity",
      "resource": {
        "resourceType": "OperationOutcome",
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        "issue": [
          {
            "extension": [
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                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
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                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "All_observations_should_have_a_performer"
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            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Best Practice Recommendation: In general, all observations should have a performer"
            },
            "expression": [
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          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/OperationOutcome/Observation-mii-exa-seltene-failure-to-thrive",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Observation-mii-exa-seltene-failure-to-thrive",
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                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "All_observations_should_have_a_performer"
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            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Best Practice Recommendation: In general, all observations should have a performer"
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            "expression": [
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          }
        ]
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    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/OperationOutcome/Observation-mii-exa-seltene-geburtsgewicht",
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        "resourceType": "OperationOutcome",
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            "extension": [
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                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
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            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "Resolved system http://unitsofmeasure.org (v3.0.1), but the definition doesn't include any codes, so the code has not been validated (for 'http://unitsofmeasure.org#g')"
            },
            "expression": [
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            "extension": [
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
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                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "All_observations_should_have_a_performer"
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            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Best Practice Recommendation: In general, all observations should have a performer"
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            "expression": [
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          }
        ]
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    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/OperationOutcome/Observation-mii-exa-seltene-geburtslaenge",
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
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                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
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                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
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            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "Resolved system http://unitsofmeasure.org (v3.0.1), but the definition doesn't include any codes, so the code has not been validated (for 'http://unitsofmeasure.org#cm')"
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            "expression": [
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
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                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
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            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
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            "expression": [
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    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/OperationOutcome/Observation-mii-exa-seltene-gestationsalter",
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                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
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            "severity": "warning",
            "code": "code-invalid",
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              {
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            ],
            "severity": "warning",
            "code": "invalid",
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              "text": "Best Practice Recommendation: In general, all observations should have a performer"
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            "expression": [
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        ]
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      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/OperationOutcome/Observation-mii-exa-seltene-hpo-assessment-change-status",
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        "resourceType": "OperationOutcome",
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            "extension": [
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                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 2
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "All_observations_should_have_a_performer"
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            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Best Practice Recommendation: In general, all observations should have a performer"
            },
            "expression": [
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            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Best Practice Recommendation: In general, all observations should have a performer"
            },
            "expression": [
              "Observation/mii-exa-seltene-hpo-assessment-excluded: Observation"
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          }
        ]
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    {
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              {
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              {
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            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Best Practice Recommendation: In general, all observations should have a performer"
            },
            "expression": [
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        ]
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            "severity": "warning",
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            "expression": [
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          {
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              {
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            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Best Practice Recommendation: In general, all observations should have a performer"
            },
            "expression": [
              "Observation/mii-exa-seltene-hueftumfang: Observation"
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
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            ],
            "severity": "warning",
            "code": "invalid",
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            "expression": [
              "Observation/mii-exa-seltene-hypertelorism: Observation"
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    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/OperationOutcome/Observation-mii-exa-seltene-icf-aktivitaet",
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            "extension": [
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              {
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
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            "severity": "warning",
            "code": "not-found",
            "details": {
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            "expression": [
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Terminology_TX_ValueSet_NotFound"
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                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
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            "code": "code-invalid",
            "details": {
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            "expression": [
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                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
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              {
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            "severity": "warning",
            "code": "invalid",
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            "expression": [
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              {
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/StructureDefinition/mii-pr-seltene-icf-assessment|2027.0.0-ballot"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'http://hl7.org/fhir/sid/icf' could not be found, so the code cannot be validated"
            },
            "expression": [
              "Observation/mii-exa-seltene-icf-koerperstruktur: Observation.code.coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 81
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/StructureDefinition/mii-pr-seltene-icf-assessment|2027.0.0-ballot"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "Resolved system http://hl7.org/fhir/sid/icf (v1.0.0), but the definition doesn't include any codes, so the code has not been validated"
            },
            "expression": [
              "Observation/mii-exa-seltene-icf-koerperstruktur: Observation.code.coding[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 29
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Terminology_TX_ValueSet_NotFound"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/StructureDefinition/mii-pr-seltene-icf-assessment|2027.0.0-ballot"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "ValueSet 'https://terminologien.bfarm.de/fhir/ValueSet/icf-q-ausmass-der-schaedigung-s' not found"
            },
            "expression": [
              "Observation/mii-exa-seltene-icf-koerperstruktur: Observation.component[0].value.ofType(CodeableConcept)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 29
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/StructureDefinition/mii-pr-seltene-icf-assessment|2027.0.0-ballot"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'https://terminologien.bfarm.de/fhir/CodeSystem/icf-q-ausmass-der-schaedigung-s' could not be found, so the code cannot be validated"
            },
            "expression": [
              "Observation/mii-exa-seltene-icf-koerperstruktur: Observation.component[0].value.ofType(CodeableConcept).coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 48
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Terminology_TX_ValueSet_NotFound"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/StructureDefinition/mii-pr-seltene-icf-assessment|2027.0.0-ballot"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "ValueSet 'https://terminologien.bfarm.de/fhir/ValueSet/icf-q-art-oder-veraenderung-in-der-entsprechenden-koerperstruktur' not found"
            },
            "expression": [
              "Observation/mii-exa-seltene-icf-koerperstruktur: Observation.component[1].value.ofType(CodeableConcept)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 48
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/StructureDefinition/mii-pr-seltene-icf-assessment|2027.0.0-ballot"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'https://terminologien.bfarm.de/fhir/CodeSystem/icf-q-art-oder-veraenderung-in-der-entsprechenden-koerperstruktur' could not be found, so the code cannot be validated"
            },
            "expression": [
              "Observation/mii-exa-seltene-icf-koerperstruktur: Observation.component[1].value.ofType(CodeableConcept).coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 67
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Terminology_TX_ValueSet_NotFound"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/StructureDefinition/mii-pr-seltene-icf-assessment|2027.0.0-ballot"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "ValueSet 'https://terminologien.bfarm.de/fhir/ValueSet/icf-q-anatomische-lokalisation' not found"
            },
            "expression": [
              "Observation/mii-exa-seltene-icf-koerperstruktur: Observation.component[2].value.ofType(CodeableConcept)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 67
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/StructureDefinition/mii-pr-seltene-icf-assessment|2027.0.0-ballot"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'https://terminologien.bfarm.de/fhir/CodeSystem/icf-q-anatomische-lokalisation' could not be found, so the code cannot be validated"
            },
            "expression": [
              "Observation/mii-exa-seltene-icf-koerperstruktur: Observation.component[2].value.ofType(CodeableConcept).coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 2
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "All_observations_should_have_a_performer"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Best Practice Recommendation: In general, all observations should have a performer"
            },
            "expression": [
              "Observation/mii-exa-seltene-icf-koerperstruktur: Observation"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/OperationOutcome/Observation-mii-exa-seltene-icf-umweltfaktor",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Observation-mii-exa-seltene-icf-umweltfaktor",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 41
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 4
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/StructureDefinition/mii-pr-seltene-icf-assessment|2027.0.0-ballot"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'http://hl7.org/fhir/sid/icf' could not be found, so the code cannot be validated"
            },
            "expression": [
              "Observation/mii-exa-seltene-icf-umweltfaktor: Observation.code.coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 43
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/StructureDefinition/mii-pr-seltene-icf-assessment|2027.0.0-ballot"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "Resolved system http://hl7.org/fhir/sid/icf (v1.0.0), but the definition doesn't include any codes, so the code has not been validated"
            },
            "expression": [
              "Observation/mii-exa-seltene-icf-umweltfaktor: Observation.code.coding[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 29
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Terminology_TX_ValueSet_NotFound"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/StructureDefinition/mii-pr-seltene-icf-assessment|2027.0.0-ballot"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "ValueSet 'https://terminologien.bfarm.de/fhir/ValueSet/icf-q-foerderfaktoren' not found"
            },
            "expression": [
              "Observation/mii-exa-seltene-icf-umweltfaktor: Observation.component[0].value.ofType(CodeableConcept)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 29
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/StructureDefinition/mii-pr-seltene-icf-assessment|2027.0.0-ballot"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'https://terminologien.bfarm.de/fhir/CodeSystem/icf-q-foerderfaktoren' could not be found, so the code cannot be validated"
            },
            "expression": [
              "Observation/mii-exa-seltene-icf-umweltfaktor: Observation.component[0].value.ofType(CodeableConcept).coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 2
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "All_observations_should_have_a_performer"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Best Practice Recommendation: In general, all observations should have a performer"
            },
            "expression": [
              "Observation/mii-exa-seltene-icf-umweltfaktor: Observation"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/OperationOutcome/Observation-mii-exa-seltene-kopfumfang",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Observation-mii-exa-seltene-kopfumfang",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 33
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 4
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/StructureDefinition/mii-pr-seltene-kopfumfang|2027.0.0-ballot"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "Resolved system http://unitsofmeasure.org (v3.0.1), but the definition doesn't include any codes, so the code has not been validated"
            },
            "expression": [
              "Observation/mii-exa-seltene-kopfumfang: Observation.value.ofType(Quantity)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 37
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 17
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/StructureDefinition/mii-pr-seltene-kopfumfang|2027.0.0-ballot"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "A definition for CodeSystem 'null' could not be found, so the code cannot be validated"
            },
            "expression": [
              "Observation/mii-exa-seltene-kopfumfang: Observation.value.ofType(Quantity).code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 33
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 4
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Terminology_PassThrough_TX_Message"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/StructureDefinition/mii-pr-seltene-kopfumfang|2027.0.0-ballot"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "Resolved system http://unitsofmeasure.org (v3.0.1), but the definition doesn't include any codes, so the code has not been validated (for 'http://unitsofmeasure.org#cm')"
            },
            "expression": [
              "Observation/mii-exa-seltene-kopfumfang: Observation.value.ofType(Quantity)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 2
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "All_observations_should_have_a_performer"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Best Practice Recommendation: In general, all observations should have a performer"
            },
            "expression": [
              "Observation/mii-exa-seltene-kopfumfang: Observation"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/OperationOutcome/Observation-mii-exa-seltene-lactate-normal",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Observation-mii-exa-seltene-lactate-normal",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 28
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 4
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Terminology_PassThrough_TX_Message"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/Observation|4.0.1"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "Resolved system http://unitsofmeasure.org (v3.0.1), but the definition doesn't include any codes, so the code has not been validated (for 'http://unitsofmeasure.org#mmol/L')"
            },
            "expression": [
              "Observation/mii-exa-seltene-lactate-normal: Observation.value.ofType(Quantity)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 2
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "All_observations_should_have_a_performer"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Best Practice Recommendation: In general, all observations should have a performer"
            },
            "expression": [
              "Observation/mii-exa-seltene-lactate-normal: Observation"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/OperationOutcome/Observation-mii-exa-seltene-lens-dislocation",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Observation-mii-exa-seltene-lens-dislocation",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 2
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              {
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                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "All_observations_should_have_a_performer"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Best Practice Recommendation: In general, all observations should have a performer"
            },
            "expression": [
              "Observation/mii-exa-seltene-symptom-mitral-regurg: Observation"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/OperationOutcome/Observation-mii-exa-seltene-taillenumfang",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Observation-mii-exa-seltene-taillenumfang",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 29
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 4
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Terminology_PassThrough_TX_Message"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/StructureDefinition/mii-pr-seltene-taillenumfang|2027.0.0-ballot"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "Resolved system http://unitsofmeasure.org (v3.0.1), but the definition doesn't include any codes, so the code has not been validated (for 'http://unitsofmeasure.org#cm')"
            },
            "expression": [
              "Observation/mii-exa-seltene-taillenumfang: Observation.value.ofType(Quantity)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 2
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "All_observations_should_have_a_performer"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Best Practice Recommendation: In general, all observations should have a performer"
            },
            "expression": [
              "Observation/mii-exa-seltene-taillenumfang: Observation"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/OperationOutcome/Observation-mii-exa-seltene-tall-stature",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Observation-mii-exa-seltene-tall-stature",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
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              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/bodyheight|4.0.1"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'http://unitsofmeasure.org' could not be found, so the code cannot be validated"
            },
            "expression": [
              "Observation/mii-exa-seltene-tall-stature: Observation.component[0].value.ofType(CodeableConcept).coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 2
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "All_observations_should_have_a_performer"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Best Practice Recommendation: In general, all observations should have a performer"
            },
            "expression": [
              "Observation/mii-exa-seltene-tall-stature: Observation"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/OperationOutcome/Observation-mii-exa-seltene-variant-fbn1-001",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Observation-mii-exa-seltene-variant-fbn1-001",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 2
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "All_observations_should_have_a_performer"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Best Practice Recommendation: In general, all observations should have a performer"
            },
            "expression": [
              "Observation/mii-exa-seltene-variant-fbn1-001: Observation"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/OperationOutcome/Observation-mii-exa-seltene-variant-smn1-001",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Observation-mii-exa-seltene-variant-smn1-001",
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          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
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              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 2
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "All_observations_should_have_a_performer"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Best Practice Recommendation: In general, all observations should have a performer"
            },
            "expression": [
              "Observation/mii-exa-seltene-variant-smn1-001: Observation"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/OperationOutcome/Observation-mii-exa-seltene-variant-smn2-001",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Observation-mii-exa-seltene-variant-smn2-001",
        "issue": [
          {
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                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 2
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "All_observations_should_have_a_performer"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Best Practice Recommendation: In general, all observations should have a performer"
            },
            "expression": [
              "Observation/mii-exa-seltene-variant-smn2-001: Observation"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/OperationOutcome/Observation-mii-exa-seltene-vsd",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Observation-mii-exa-seltene-vsd",
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          {
            "extension": [
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                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
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              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 2
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "All_observations_should_have_a_performer"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Best Practice Recommendation: In general, all observations should have a performer"
            },
            "expression": [
              "Observation/mii-exa-seltene-vsd: Observation"
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          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/OperationOutcome/Patient-mii-exa-seltene-patient-marfan-001",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Patient-mii-exa-seltene-patient-marfan-001",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 6
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
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              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/Patient|4.0.1"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/sid/patient-id'"
            },
            "expression": [
              "Patient/mii-exa-seltene-patient-marfan-001: Patient.identifier[0].system"
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          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/OperationOutcome/Patient-mii-exa-seltene-patient-sma-001",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Patient-mii-exa-seltene-patient-sma-001",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 6
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 82
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/Patient|4.0.1"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/sid/patient-id'"
            },
            "expression": [
              "Patient/mii-exa-seltene-patient-sma-001: Patient.identifier[0].system"
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          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/OperationOutcome/Patient-mii-exa-seltene-patient",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Patient-mii-exa-seltene-patient",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 20
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 64
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/core/modul-person/StructureDefinition/Patient|2027.0.0-ballot"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'http://test-krankenhaus.de/fhir/sid/patienten'"
            },
            "expression": [
              "Patient/mii-exa-seltene-patient: Patient.identifier[0].system"
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          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/OperationOutcome/Procedure-mii-exa-seltene-narse-gentherapie-sma",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Procedure-mii-exa-seltene-narse-gentherapie-sma"
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/OperationOutcome/Procedure-mii-exa-seltene-narse-stoffwechseltherapie-pompe",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Procedure-mii-exa-seltene-narse-stoffwechseltherapie-pompe"
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/OperationOutcome/Procedure-mii-exa-seltene-procedure-aortic-planned",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Procedure-mii-exa-seltene-procedure-aortic-planned"
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/OperationOutcome/Procedure-mii-exa-seltene-procedure-cataract-surgery",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Procedure-mii-exa-seltene-procedure-cataract-surgery"
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/OperationOutcome/Procedure-mii-exa-seltene-procedure-gentherapy-001",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Procedure-mii-exa-seltene-procedure-gentherapy-001"
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/OperationOutcome/ResearchStudy-mii-exa-seltene-register-euro-nmd",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ResearchStudy-mii-exa-seltene-register-euro-nmd",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 6
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 60
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/ResearchStudy|4.0.1"
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            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://ern-euro-nmd.eu/fhir/sid/registry'"
            },
            "expression": [
              "ResearchStudy/mii-exa-seltene-register-euro-nmd: ResearchStudy.identifier[0].system"
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          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/OperationOutcome/ResearchSubject-mii-exa-seltene-registerteilnahme",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ResearchSubject-mii-exa-seltene-registerteilnahme",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 19
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 59
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/StructureDefinition/mii-pr-seltene-registerteilnahme|2027.0.0-ballot"
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            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://ern-euro-nmd.eu/fhir/sid/subject'"
            },
            "expression": [
              "ResearchSubject/mii-exa-seltene-registerteilnahme: ResearchSubject.identifier[0].system"
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        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/OperationOutcome/ServiceRequest-mii-exa-seltene-example-early-detection-recommendation",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ServiceRequest-mii-exa-seltene-example-early-detection-recommendation"
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/OperationOutcome/ServiceRequest-mii-exa-seltene-example-nutrition-therapy-recommendation",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ServiceRequest-mii-exa-seltene-example-nutrition-therapy-recommendation"
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/OperationOutcome/ServiceRequest-mii-exa-seltene-studieneinschluss-anfrage",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ServiceRequest-mii-exa-seltene-studieneinschluss-anfrage"
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/OperationOutcome/ServiceRequest-mii-exa-seltene-therapieempfehlung-aortenwurzelersatz-marfan",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ServiceRequest-mii-exa-seltene-therapieempfehlung-aortenwurzelersatz-marfan"
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    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/OperationOutcome/ServiceRequest-mii-exa-seltene-therapieempfehlung-genetische-beratung",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ServiceRequest-mii-exa-seltene-therapieempfehlung-genetische-beratung"
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/OperationOutcome/ServiceRequest-mii-exa-seltene-therapieempfehlung-physiotherapie-sma",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ServiceRequest-mii-exa-seltene-therapieempfehlung-physiotherapie-sma",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 49
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 25
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/StructureDefinition/mii-pr-seltene-therapieempfehlung-nicht-medikamentoes|2027.0.0-ballot"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "A definition for CodeSystem 'null' could not be found, so the code cannot be validated"
            },
            "expression": [
              "ServiceRequest/mii-exa-seltene-therapieempfehlung-physiotherapie-sma: ServiceRequest.occurrence.ofType(Timing).repeat.periodUnit"
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          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/OperationOutcome/StructureDefinition-mii-ex-seltene-empfehlung-prioritaet",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "StructureDefinition-mii-ex-seltene-empfehlung-prioritaet",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 46739
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "StructureDefinition/mii-ex-seltene-empfehlung-prioritaet: StructureDefinition.jurisdiction[0].coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "Publisher"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The Implementation Guide contains no examples for this extension"
            },
            "expression": [
              "StructureDefinition.where(url = 'https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/StructureDefinition/mii-ex-seltene-empfehlung-prioritaet')"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/OperationOutcome/StructureDefinition-mii-ex-seltene-empfehlung-publikation",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "StructureDefinition-mii-ex-seltene-empfehlung-publikation",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 54848
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "StructureDefinition/mii-ex-seltene-empfehlung-publikation: StructureDefinition.jurisdiction[0].coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 70502
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "The slice 'valueIdentifier' on path 'Extension.value[x]' is not marked as 'must-support' which is not consistent with the element that defines the slicing, where 'must-support' is true"
            },
            "expression": [
              "StructureDefinition/mii-ex-seltene-empfehlung-publikation: StructureDefinition.snapshot"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 70502
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "The slice 'valueString' on path 'Extension.value[x]' is not marked as 'must-support' which is not consistent with the element that defines the slicing, where 'must-support' is true"
            },
            "expression": [
              "StructureDefinition/mii-ex-seltene-empfehlung-publikation: StructureDefinition.snapshot"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "Publisher"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The Implementation Guide contains no examples for this extension"
            },
            "expression": [
              "StructureDefinition.where(url = 'https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/StructureDefinition/mii-ex-seltene-empfehlung-publikation')"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/OperationOutcome/StructureDefinition-mii-ex-seltene-penetrance",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "StructureDefinition-mii-ex-seltene-penetrance",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 60451
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "StructureDefinition/mii-ex-seltene-penetrance: StructureDefinition.jurisdiction[0].coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "Publisher"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The Implementation Guide contains no examples for this extension"
            },
            "expression": [
              "StructureDefinition.where(url = 'https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/StructureDefinition/mii-ex-seltene-penetrance')"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/OperationOutcome/StructureDefinition-mii-ex-seltene-register",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "StructureDefinition-mii-ex-seltene-register",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 28823
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "StructureDefinition/mii-ex-seltene-register: StructureDefinition.jurisdiction[0].coding[0].system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/OperationOutcome/StructureDefinition-mii-ex-seltene-von-se-betroffen",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "StructureDefinition-mii-ex-seltene-von-se-betroffen",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 29856
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "StructureDefinition/mii-ex-seltene-von-se-betroffen: StructureDefinition.jurisdiction[0].coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "SD_CONTEXT_SHOULD_NOT_BE_ELEMENT"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "Review the extension type for mii-ex-seltene-von-se-betroffen: extensions should not have a context of Element unless it's really intended that they can be used anywhere"
            },
            "expression": [
              "StructureDefinition/mii-ex-seltene-von-se-betroffen: StructureDefinition.context[0]"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/OperationOutcome/StructureDefinition-mii-lm-seltene",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "StructureDefinition-mii-lm-seltene",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 346691
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "StructureDefinition/mii-lm-seltene: StructureDefinition.jurisdiction[0].coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 497315
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TYPE_SPECIFIC_CHECKS_DT_CANONICAL_MULTIPLE_POSSIBLE_VERSIONS"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "There are multiple different potential matches for the url 'http://hl7.org/fhir/StructureDefinition/organization-period'. It might be a good idea to fix to the correct version to reduce the likelihood of a wrong version being selected by an implementation/implementer, or use the [IG Parameter `pin-canonicals`](https://hl7.org/fhir/tools/CodeSystem-ig-parameters.html). Using version '5.3.0', found versions: 4.0.1 (from hl7.fhir.r4.core#4.0.1), 5.1.0 (from hl7.fhir.uv.extensions.r4#5.1.0), 5.2.0 (from hl7.fhir.uv.extensions.r4#5.2.0), 5.3.0 (from hl7.fhir.uv.extensions.r4#5.3.0). Suggested fix: change the canonical reference from 'http://hl7.org/fhir/StructureDefinition/organization-period' to 'http://hl7.org/fhir/StructureDefinition/organization-period|5.3.0'"
            },
            "expression": [
              "StructureDefinition/mii-lm-seltene: StructureDefinition.snapshot.element[150].type[0].profile[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 526837
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TYPE_SPECIFIC_CHECKS_DT_CANONICAL_MULTIPLE_POSSIBLE_VERSIONS"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "There are multiple different potential matches for the url 'http://hl7.org/fhir/StructureDefinition/organization-period'. It might be a good idea to fix to the correct version to reduce the likelihood of a wrong version being selected by an implementation/implementer, or use the [IG Parameter `pin-canonicals`](https://hl7.org/fhir/tools/CodeSystem-ig-parameters.html). Using version '5.3.0', found versions: 4.0.1 (from hl7.fhir.r4.core#4.0.1), 5.1.0 (from hl7.fhir.uv.extensions.r4#5.1.0), 5.2.0 (from hl7.fhir.uv.extensions.r4#5.2.0), 5.3.0 (from hl7.fhir.uv.extensions.r4#5.3.0). Suggested fix: change the canonical reference from 'http://hl7.org/fhir/StructureDefinition/organization-period' to 'http://hl7.org/fhir/StructureDefinition/organization-period|5.3.0'"
            },
            "expression": [
              "StructureDefinition/mii-lm-seltene: StructureDefinition.differential.element[82].type[0].profile[0]"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/OperationOutcome/StructureDefinition-mii-pr-seltene-blutgruppe",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "StructureDefinition-mii-pr-seltene-blutgruppe",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 160134
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "StructureDefinition/mii-pr-seltene-blutgruppe: StructureDefinition.jurisdiction[0].coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "Publisher"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The Implementation Guide contains no examples for this profile"
            },
            "expression": [
              "StructureDefinition.where(url = 'https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/StructureDefinition/mii-pr-seltene-blutgruppe')"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/OperationOutcome/StructureDefinition-mii-pr-seltene-bodymassindex",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "StructureDefinition-mii-pr-seltene-bodymassindex",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 87322
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "StructureDefinition/mii-pr-seltene-bodymassindex: StructureDefinition.jurisdiction[0].coding[0].system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/OperationOutcome/StructureDefinition-mii-pr-seltene-clinical-diagnosis",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "StructureDefinition-mii-pr-seltene-clinical-diagnosis",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 132214
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "StructureDefinition/mii-pr-seltene-clinical-diagnosis: StructureDefinition.jurisdiction[0].coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 156894
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TYPE_SPECIFIC_CHECKS_DT_CANONICAL_MULTIPLE_POSSIBLE_VERSIONS"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "There are multiple different potential matches for the url 'http://hl7.org/fhir/StructureDefinition/condition-related'. It might be a good idea to fix to the correct version to reduce the likelihood of a wrong version being selected by an implementation/implementer, or use the [IG Parameter `pin-canonicals`](https://hl7.org/fhir/tools/CodeSystem-ig-parameters.html). Using version '5.3.0', found versions: 4.0.1 (from hl7.fhir.r4.core#4.0.1), 5.1.0 (from hl7.fhir.uv.extensions.r4#5.1.0), 5.2.0 (from hl7.fhir.uv.extensions.r4#5.2.0), 5.3.0 (from hl7.fhir.uv.extensions.r4#5.3.0). Suggested fix: change the canonical reference from 'http://hl7.org/fhir/StructureDefinition/condition-related' to 'http://hl7.org/fhir/StructureDefinition/condition-related|5.3.0'"
            },
            "expression": [
              "StructureDefinition/mii-pr-seltene-clinical-diagnosis: StructureDefinition.snapshot.element[16].type[0].profile[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 162210
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TYPE_SPECIFIC_CHECKS_DT_CANONICAL_MULTIPLE_POSSIBLE_VERSIONS"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "There are multiple different potential matches for the url 'http://hl7.org/fhir/StructureDefinition/condition-assertedDate'. It might be a good idea to fix to the correct version to reduce the likelihood of a wrong version being selected by an implementation/implementer, or use the [IG Parameter `pin-canonicals`](https://hl7.org/fhir/tools/CodeSystem-ig-parameters.html). Using version '5.3.0', found versions: 4.0.1 (from hl7.fhir.r4.core#4.0.1), 5.1.0 (from hl7.fhir.uv.extensions.r4#5.1.0), 5.2.0 (from hl7.fhir.uv.extensions.r4#5.2.0), 5.3.0 (from hl7.fhir.uv.extensions.r4#5.3.0). Suggested fix: change the canonical reference from 'http://hl7.org/fhir/StructureDefinition/condition-assertedDate' to 'http://hl7.org/fhir/StructureDefinition/condition-assertedDate|5.3.0'"
            },
            "expression": [
              "StructureDefinition/mii-pr-seltene-clinical-diagnosis: StructureDefinition.snapshot.element[21].type[0].profile[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 319751
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TYPE_SPECIFIC_CHECKS_DT_CANONICAL_MULTIPLE_POSSIBLE_VERSIONS"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "There are multiple different potential matches for the url 'http://hl7.org/fhir/StructureDefinition/bodySite'. It might be a good idea to fix to the correct version to reduce the likelihood of a wrong version being selected by an implementation/implementer, or use the [IG Parameter `pin-canonicals`](https://hl7.org/fhir/tools/CodeSystem-ig-parameters.html). Using version '5.3.0', found versions: 4.0.1 (from hl7.fhir.r4.core#4.0.1), 5.1.0 (from hl7.fhir.uv.extensions.r4#5.1.0), 5.2.0 (from hl7.fhir.uv.extensions.r4#5.2.0), 5.3.0 (from hl7.fhir.uv.extensions.r4#5.3.0). Suggested fix: change the canonical reference from 'http://hl7.org/fhir/StructureDefinition/bodySite' to 'http://hl7.org/fhir/StructureDefinition/bodySite|5.3.0'"
            },
            "expression": [
              "StructureDefinition/mii-pr-seltene-clinical-diagnosis: StructureDefinition.snapshot.element[138].type[0].profile[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "SD_ED_EXPERIMENTAL_BINDING"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The definition for the element 'Condition.code.coding' binds to the value set 'https://www.medizininformatik-initiative.de/fhir/core/modul-diagnose/ValueSet/diagnoses-sct' which is experimental, but this structure is not labeled as experimental"
            },
            "expression": [
              "StructureDefinition/mii-pr-seltene-clinical-diagnosis: StructureDefinition.snapshot.element[110].binding"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "SD_ED_EXPERIMENTAL_BINDING"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The definition for the element 'Condition.code.coding' binds to the value set 'https://www.medizininformatik-initiative.de/fhir/core/modul-diagnose/ValueSet/mii-vs-diagnose-orphanet' which is experimental, but this structure is not labeled as experimental"
            },
            "expression": [
              "StructureDefinition/mii-pr-seltene-clinical-diagnosis: StructureDefinition.snapshot.element[118].binding"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "SD_ED_EXPERIMENTAL_BINDING"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The definition for the element 'Condition.bodySite.coding' binds to the value set 'https://www.medizininformatik-initiative.de/fhir/core/modul-diagnose/ValueSet/mii-vs-diagnose-bodystructure-snomed' which is experimental, but this structure is not labeled as experimental"
            },
            "expression": [
              "StructureDefinition/mii-pr-seltene-clinical-diagnosis: StructureDefinition.snapshot.element[140].binding"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/OperationOutcome/StructureDefinition-mii-pr-seltene-clinical-impression",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "StructureDefinition-mii-pr-seltene-clinical-impression",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 125678
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "StructureDefinition/mii-pr-seltene-clinical-impression: StructureDefinition.jurisdiction[0].coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 182320
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "The slice 'effectiveDateTime' on path 'ClinicalImpression.effective[x]' is not marked as 'must-support' which is not consistent with the element that defines the slicing, where 'must-support' is true"
            },
            "expression": [
              "StructureDefinition/mii-pr-seltene-clinical-impression: StructureDefinition.snapshot"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 182320
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "The slice 'effectivePeriod' on path 'ClinicalImpression.effective[x]' is not marked as 'must-support' which is not consistent with the element that defines the slicing, where 'must-support' is true"
            },
            "expression": [
              "StructureDefinition/mii-pr-seltene-clinical-impression: StructureDefinition.snapshot"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/OperationOutcome/StructureDefinition-mii-pr-seltene-consanguinity",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "StructureDefinition-mii-pr-seltene-consanguinity",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 111296
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "StructureDefinition/mii-pr-seltene-consanguinity: StructureDefinition.jurisdiction[0].coding[0].system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/OperationOutcome/StructureDefinition-mii-pr-seltene-familienanamnese",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "StructureDefinition-mii-pr-seltene-familienanamnese",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 153070
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "StructureDefinition/mii-pr-seltene-familienanamnese: StructureDefinition.jurisdiction[0].coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "SD_ED_EXPERIMENTAL_BINDING"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The definition for the element 'FamilyMemberHistory.reasonCode.coding' binds to the value set 'https://www.medizininformatik-initiative.de/fhir/core/modul-diagnose/ValueSet/diagnoses-sct' which is experimental, but this structure is not labeled as experimental"
            },
            "expression": [
              "StructureDefinition/mii-pr-seltene-familienanamnese: StructureDefinition.snapshot.element[63].binding"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "SD_ED_EXPERIMENTAL_BINDING"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The definition for the element 'FamilyMemberHistory.reasonCode.coding' binds to the value set 'https://www.medizininformatik-initiative.de/fhir/core/modul-diagnose/ValueSet/mii-vs-diagnose-orphanet' which is experimental, but this structure is not labeled as experimental"
            },
            "expression": [
              "StructureDefinition/mii-pr-seltene-familienanamnese: StructureDefinition.snapshot.element[71].binding"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "SD_ED_EXPERIMENTAL_BINDING"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The definition for the element 'FamilyMemberHistory.condition.code.coding' binds to the value set 'https://www.medizininformatik-initiative.de/fhir/core/modul-diagnose/ValueSet/diagnoses-sct' which is experimental, but this structure is not labeled as experimental"
            },
            "expression": [
              "StructureDefinition/mii-pr-seltene-familienanamnese: StructureDefinition.snapshot.element[110].binding"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "SD_ED_EXPERIMENTAL_BINDING"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The definition for the element 'FamilyMemberHistory.condition.code.coding' binds to the value set 'https://www.medizininformatik-initiative.de/fhir/core/modul-diagnose/ValueSet/mii-vs-diagnose-orphanet' which is experimental, but this structure is not labeled as experimental"
            },
            "expression": [
              "StructureDefinition/mii-pr-seltene-familienanamnese: StructureDefinition.snapshot.element[118].binding"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 346686
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "The slice 'deceasedBoolean' on path 'FamilyMemberHistory.deceased[x]' is not marked as 'must-support' which is not consistent with the element that defines the slicing, where 'must-support' is true"
            },
            "expression": [
              "StructureDefinition/mii-pr-seltene-familienanamnese: StructureDefinition.snapshot"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 346686
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "The slice 'deceasedDate' on path 'FamilyMemberHistory.deceased[x]' is not marked as 'must-support' which is not consistent with the element that defines the slicing, where 'must-support' is true"
            },
            "expression": [
              "StructureDefinition/mii-pr-seltene-familienanamnese: StructureDefinition.snapshot"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 346686
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "The slice 'deceasedAge' on path 'FamilyMemberHistory.deceased[x]' is not marked as 'must-support' which is not consistent with the element that defines the slicing, where 'must-support' is true"
            },
            "expression": [
              "StructureDefinition/mii-pr-seltene-familienanamnese: StructureDefinition.snapshot"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 346686
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "The slice 'onsetAge' on path 'FamilyMemberHistory.condition.onset[x]' is not marked as 'must-support' which is not consistent with the element that defines the slicing, where 'must-support' is true"
            },
            "expression": [
              "StructureDefinition/mii-pr-seltene-familienanamnese: StructureDefinition.snapshot"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/OperationOutcome/StructureDefinition-mii-pr-seltene-geburtsgewicht",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "StructureDefinition-mii-pr-seltene-geburtsgewicht",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 101245
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "StructureDefinition/mii-pr-seltene-geburtsgewicht: StructureDefinition.jurisdiction[0].coding[0].system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/OperationOutcome/StructureDefinition-mii-pr-seltene-geburtslaenge",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "StructureDefinition-mii-pr-seltene-geburtslaenge",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 101240
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "StructureDefinition/mii-pr-seltene-geburtslaenge: StructureDefinition.jurisdiction[0].coding[0].system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/OperationOutcome/StructureDefinition-mii-pr-seltene-genetic-diagnosis",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "StructureDefinition-mii-pr-seltene-genetic-diagnosis",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 166310
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "StructureDefinition/mii-pr-seltene-genetic-diagnosis: StructureDefinition.jurisdiction[0].coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 190992
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TYPE_SPECIFIC_CHECKS_DT_CANONICAL_MULTIPLE_POSSIBLE_VERSIONS"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "There are multiple different potential matches for the url 'http://hl7.org/fhir/StructureDefinition/condition-related'. It might be a good idea to fix to the correct version to reduce the likelihood of a wrong version being selected by an implementation/implementer, or use the [IG Parameter `pin-canonicals`](https://hl7.org/fhir/tools/CodeSystem-ig-parameters.html). Using version '5.3.0', found versions: 4.0.1 (from hl7.fhir.r4.core#4.0.1), 5.1.0 (from hl7.fhir.uv.extensions.r4#5.1.0), 5.2.0 (from hl7.fhir.uv.extensions.r4#5.2.0), 5.3.0 (from hl7.fhir.uv.extensions.r4#5.3.0). Suggested fix: change the canonical reference from 'http://hl7.org/fhir/StructureDefinition/condition-related' to 'http://hl7.org/fhir/StructureDefinition/condition-related|5.3.0'"
            },
            "expression": [
              "StructureDefinition/mii-pr-seltene-genetic-diagnosis: StructureDefinition.snapshot.element[16].type[0].profile[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 196308
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TYPE_SPECIFIC_CHECKS_DT_CANONICAL_MULTIPLE_POSSIBLE_VERSIONS"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "There are multiple different potential matches for the url 'http://hl7.org/fhir/StructureDefinition/condition-assertedDate'. It might be a good idea to fix to the correct version to reduce the likelihood of a wrong version being selected by an implementation/implementer, or use the [IG Parameter `pin-canonicals`](https://hl7.org/fhir/tools/CodeSystem-ig-parameters.html). Using version '5.3.0', found versions: 4.0.1 (from hl7.fhir.r4.core#4.0.1), 5.1.0 (from hl7.fhir.uv.extensions.r4#5.1.0), 5.2.0 (from hl7.fhir.uv.extensions.r4#5.2.0), 5.3.0 (from hl7.fhir.uv.extensions.r4#5.3.0). Suggested fix: change the canonical reference from 'http://hl7.org/fhir/StructureDefinition/condition-assertedDate' to 'http://hl7.org/fhir/StructureDefinition/condition-assertedDate|5.3.0'"
            },
            "expression": [
              "StructureDefinition/mii-pr-seltene-genetic-diagnosis: StructureDefinition.snapshot.element[21].type[0].profile[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 355247
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TYPE_SPECIFIC_CHECKS_DT_CANONICAL_MULTIPLE_POSSIBLE_VERSIONS"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "There are multiple different potential matches for the url 'http://hl7.org/fhir/StructureDefinition/bodySite'. It might be a good idea to fix to the correct version to reduce the likelihood of a wrong version being selected by an implementation/implementer, or use the [IG Parameter `pin-canonicals`](https://hl7.org/fhir/tools/CodeSystem-ig-parameters.html). Using version '5.3.0', found versions: 4.0.1 (from hl7.fhir.r4.core#4.0.1), 5.1.0 (from hl7.fhir.uv.extensions.r4#5.1.0), 5.2.0 (from hl7.fhir.uv.extensions.r4#5.2.0), 5.3.0 (from hl7.fhir.uv.extensions.r4#5.3.0). Suggested fix: change the canonical reference from 'http://hl7.org/fhir/StructureDefinition/bodySite' to 'http://hl7.org/fhir/StructureDefinition/bodySite|5.3.0'"
            },
            "expression": [
              "StructureDefinition/mii-pr-seltene-genetic-diagnosis: StructureDefinition.snapshot.element[139].type[0].profile[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "SD_ED_EXPERIMENTAL_BINDING"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The definition for the element 'Condition.code.coding' binds to the value set 'https://www.medizininformatik-initiative.de/fhir/core/modul-diagnose/ValueSet/diagnoses-sct' which is experimental, but this structure is not labeled as experimental"
            },
            "expression": [
              "StructureDefinition/mii-pr-seltene-genetic-diagnosis: StructureDefinition.snapshot.element[111].binding"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "SD_ED_EXPERIMENTAL_BINDING"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The definition for the element 'Condition.code.coding' binds to the value set 'https://www.medizininformatik-initiative.de/fhir/core/modul-diagnose/ValueSet/mii-vs-diagnose-orphanet' which is experimental, but this structure is not labeled as experimental"
            },
            "expression": [
              "StructureDefinition/mii-pr-seltene-genetic-diagnosis: StructureDefinition.snapshot.element[119].binding"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "SD_ED_EXPERIMENTAL_BINDING"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The definition for the element 'Condition.bodySite.coding' binds to the value set 'https://www.medizininformatik-initiative.de/fhir/core/modul-diagnose/ValueSet/mii-vs-diagnose-bodystructure-snomed' which is experimental, but this structure is not labeled as experimental"
            },
            "expression": [
              "StructureDefinition/mii-pr-seltene-genetic-diagnosis: StructureDefinition.snapshot.element[141].binding"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/OperationOutcome/StructureDefinition-mii-pr-seltene-gestationsalter",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "StructureDefinition-mii-pr-seltene-gestationsalter",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 83309
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "StructureDefinition/mii-pr-seltene-gestationsalter: StructureDefinition.jurisdiction[0].coding[0].system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/OperationOutcome/StructureDefinition-mii-pr-seltene-hpo-assessment",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "StructureDefinition-mii-pr-seltene-hpo-assessment",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 179111
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "StructureDefinition/mii-pr-seltene-hpo-assessment: StructureDefinition.jurisdiction[0].coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 324094
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "The slice 'effectiveDateTime' on path 'Observation.effective[x]' is not marked as 'must-support' which is not consistent with the element that defines the slicing, where 'must-support' is true"
            },
            "expression": [
              "StructureDefinition/mii-pr-seltene-hpo-assessment: StructureDefinition.snapshot"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 324094
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "The slice 'effectivePeriod' on path 'Observation.effective[x]' is not marked as 'must-support' which is not consistent with the element that defines the slicing, where 'must-support' is true"
            },
            "expression": [
              "StructureDefinition/mii-pr-seltene-hpo-assessment: StructureDefinition.snapshot"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/OperationOutcome/StructureDefinition-mii-pr-seltene-hueftumfang",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "StructureDefinition-mii-pr-seltene-hueftumfang",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 87405
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "StructureDefinition/mii-pr-seltene-hueftumfang: StructureDefinition.jurisdiction[0].coding[0].system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/OperationOutcome/StructureDefinition-mii-pr-seltene-icf-assessment",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "StructureDefinition-mii-pr-seltene-icf-assessment",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 333546
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "StructureDefinition/mii-pr-seltene-icf-assessment: StructureDefinition.jurisdiction[0].coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 449142
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TYPE_SPECIFIC_CHECKS_DT_CANONICAL_RESOLVE"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "A definition could not be found for Canonical URL 'https://terminologien.bfarm.de/fhir/ValueSet/icf-q-ausmass-der-schaedigung'"
            },
            "expression": [
              "StructureDefinition/mii-pr-seltene-icf-assessment: StructureDefinition.snapshot.element[75].binding.valueSet"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 464467
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TYPE_SPECIFIC_CHECKS_DT_CANONICAL_RESOLVE"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "A definition could not be found for Canonical URL 'https://terminologien.bfarm.de/fhir/ValueSet/icf-q-ausmass-der-schaedigung-s'"
            },
            "expression": [
              "StructureDefinition/mii-pr-seltene-icf-assessment: StructureDefinition.snapshot.element[84].binding.valueSet"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 479646
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TYPE_SPECIFIC_CHECKS_DT_CANONICAL_RESOLVE"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "A definition could not be found for Canonical URL 'https://terminologien.bfarm.de/fhir/ValueSet/icf-q-art-oder-veraenderung-in-der-entsprechenden-koerperstruktur'"
            },
            "expression": [
              "StructureDefinition/mii-pr-seltene-icf-assessment: StructureDefinition.snapshot.element[93].binding.valueSet"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 494706
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TYPE_SPECIFIC_CHECKS_DT_CANONICAL_RESOLVE"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "A definition could not be found for Canonical URL 'https://terminologien.bfarm.de/fhir/ValueSet/icf-q-anatomische-lokalisation'"
            },
            "expression": [
              "StructureDefinition/mii-pr-seltene-icf-assessment: StructureDefinition.snapshot.element[102].binding.valueSet"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 509807
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TYPE_SPECIFIC_CHECKS_DT_CANONICAL_RESOLVE"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "A definition could not be found for Canonical URL 'https://terminologien.bfarm.de/fhir/ValueSet/icf-q-leistungsfaehigkeit-und-leistung'"
            },
            "expression": [
              "StructureDefinition/mii-pr-seltene-icf-assessment: StructureDefinition.snapshot.element[111].binding.valueSet"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 524975
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TYPE_SPECIFIC_CHECKS_DT_CANONICAL_RESOLVE"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "A definition could not be found for Canonical URL 'https://terminologien.bfarm.de/fhir/ValueSet/icf-q-leistungsfaehigkeit-und-leistung'"
            },
            "expression": [
              "StructureDefinition/mii-pr-seltene-icf-assessment: StructureDefinition.snapshot.element[120].binding.valueSet"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 539998
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TYPE_SPECIFIC_CHECKS_DT_CANONICAL_RESOLVE"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "A definition could not be found for Canonical URL 'https://terminologien.bfarm.de/fhir/ValueSet/icf-q-barrieren'"
            },
            "expression": [
              "StructureDefinition/mii-pr-seltene-icf-assessment: StructureDefinition.snapshot.element[129].binding.valueSet"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 555055
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TYPE_SPECIFIC_CHECKS_DT_CANONICAL_RESOLVE"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "A definition could not be found for Canonical URL 'https://terminologien.bfarm.de/fhir/ValueSet/icf-q-foerderfaktoren'"
            },
            "expression": [
              "StructureDefinition/mii-pr-seltene-icf-assessment: StructureDefinition.snapshot.element[138].binding.valueSet"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 566473
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TYPE_SPECIFIC_CHECKS_DT_CANONICAL_RESOLVE"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "A definition could not be found for Canonical URL 'https://terminologien.bfarm.de/fhir/ValueSet/icf-q-ausmass-der-schaedigung'"
            },
            "expression": [
              "StructureDefinition/mii-pr-seltene-icf-assessment: StructureDefinition.differential.element[19].binding.valueSet"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 567546
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TYPE_SPECIFIC_CHECKS_DT_CANONICAL_RESOLVE"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "A definition could not be found for Canonical URL 'https://terminologien.bfarm.de/fhir/ValueSet/icf-q-ausmass-der-schaedigung-s'"
            },
            "expression": [
              "StructureDefinition/mii-pr-seltene-icf-assessment: StructureDefinition.differential.element[22].binding.valueSet"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 568329
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TYPE_SPECIFIC_CHECKS_DT_CANONICAL_RESOLVE"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "A definition could not be found for Canonical URL 'https://terminologien.bfarm.de/fhir/ValueSet/icf-q-art-oder-veraenderung-in-der-entsprechenden-koerperstruktur'"
            },
            "expression": [
              "StructureDefinition/mii-pr-seltene-icf-assessment: StructureDefinition.differential.element[25].binding.valueSet"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 569188
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TYPE_SPECIFIC_CHECKS_DT_CANONICAL_RESOLVE"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "A definition could not be found for Canonical URL 'https://terminologien.bfarm.de/fhir/ValueSet/icf-q-anatomische-lokalisation'"
            },
            "expression": [
              "StructureDefinition/mii-pr-seltene-icf-assessment: StructureDefinition.differential.element[28].binding.valueSet"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 569950
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TYPE_SPECIFIC_CHECKS_DT_CANONICAL_RESOLVE"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "A definition could not be found for Canonical URL 'https://terminologien.bfarm.de/fhir/ValueSet/icf-q-leistungsfaehigkeit-und-leistung'"
            },
            "expression": [
              "StructureDefinition/mii-pr-seltene-icf-assessment: StructureDefinition.differential.element[31].binding.valueSet"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 570956
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TYPE_SPECIFIC_CHECKS_DT_CANONICAL_RESOLVE"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "A definition could not be found for Canonical URL 'https://terminologien.bfarm.de/fhir/ValueSet/icf-q-leistungsfaehigkeit-und-leistung'"
            },
            "expression": [
              "StructureDefinition/mii-pr-seltene-icf-assessment: StructureDefinition.differential.element[34].binding.valueSet"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 571664
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TYPE_SPECIFIC_CHECKS_DT_CANONICAL_RESOLVE"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "A definition could not be found for Canonical URL 'https://terminologien.bfarm.de/fhir/ValueSet/icf-q-barrieren'"
            },
            "expression": [
              "StructureDefinition/mii-pr-seltene-icf-assessment: StructureDefinition.differential.element[37].binding.valueSet"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 572562
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TYPE_SPECIFIC_CHECKS_DT_CANONICAL_RESOLVE"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "A definition could not be found for Canonical URL 'https://terminologien.bfarm.de/fhir/ValueSet/icf-q-foerderfaktoren'"
            },
            "expression": [
              "StructureDefinition/mii-pr-seltene-icf-assessment: StructureDefinition.differential.element[40].binding.valueSet"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "SD_ED_BIND_UNKNOWN_VS"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The valueSet reference https://terminologien.bfarm.de/fhir/ValueSet/icf-q-ausmass-der-schaedigung on element Observation.component.value[x] could not be resolved"
            },
            "expression": [
              "StructureDefinition/mii-pr-seltene-icf-assessment: StructureDefinition.differential.element[19].binding"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "SD_ED_BIND_UNKNOWN_VS"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The valueSet reference https://terminologien.bfarm.de/fhir/ValueSet/icf-q-ausmass-der-schaedigung-s on element Observation.component.value[x] could not be resolved"
            },
            "expression": [
              "StructureDefinition/mii-pr-seltene-icf-assessment: StructureDefinition.differential.element[22].binding"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "SD_ED_BIND_UNKNOWN_VS"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The valueSet reference https://terminologien.bfarm.de/fhir/ValueSet/icf-q-art-oder-veraenderung-in-der-entsprechenden-koerperstruktur on element Observation.component.value[x] could not be resolved"
            },
            "expression": [
              "StructureDefinition/mii-pr-seltene-icf-assessment: StructureDefinition.differential.element[25].binding"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "SD_ED_BIND_UNKNOWN_VS"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The valueSet reference https://terminologien.bfarm.de/fhir/ValueSet/icf-q-anatomische-lokalisation on element Observation.component.value[x] could not be resolved"
            },
            "expression": [
              "StructureDefinition/mii-pr-seltene-icf-assessment: StructureDefinition.differential.element[28].binding"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "SD_ED_BIND_UNKNOWN_VS"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The valueSet reference https://terminologien.bfarm.de/fhir/ValueSet/icf-q-leistungsfaehigkeit-und-leistung on element Observation.component.value[x] could not be resolved"
            },
            "expression": [
              "StructureDefinition/mii-pr-seltene-icf-assessment: StructureDefinition.differential.element[31].binding"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "SD_ED_BIND_UNKNOWN_VS"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The valueSet reference https://terminologien.bfarm.de/fhir/ValueSet/icf-q-leistungsfaehigkeit-und-leistung on element Observation.component.value[x] could not be resolved"
            },
            "expression": [
              "StructureDefinition/mii-pr-seltene-icf-assessment: StructureDefinition.differential.element[34].binding"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "SD_ED_BIND_UNKNOWN_VS"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The valueSet reference https://terminologien.bfarm.de/fhir/ValueSet/icf-q-barrieren on element Observation.component.value[x] could not be resolved"
            },
            "expression": [
              "StructureDefinition/mii-pr-seltene-icf-assessment: StructureDefinition.differential.element[37].binding"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "SD_ED_BIND_UNKNOWN_VS"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The valueSet reference https://terminologien.bfarm.de/fhir/ValueSet/icf-q-foerderfaktoren on element Observation.component.value[x] could not be resolved"
            },
            "expression": [
              "StructureDefinition/mii-pr-seltene-icf-assessment: StructureDefinition.differential.element[40].binding"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 339296
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "FHIRPATH_COLLECTION_STATUS_OPERATION_LEFT"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "mii-icf-1: The left side is inherently a collection, and so the expression 'code.coding.code != 'extent-of-impairment'' may fail or return false if there is more than one item in the content being evaluated"
            },
            "expression": [
              "StructureDefinition/mii-pr-seltene-icf-assessment: StructureDefinition.snapshot.element[0].constraint[7]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 339836
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "FHIRPATH_COLLECTION_STATUS_OPERATION_LEFT"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "mii-icf-2: The left side is inherently a collection, and so the expression 'code.coding.code != 'extent-of-impairment-structure'' may fail or return false if there is more than one item in the content being evaluated"
            },
            "expression": [
              "StructureDefinition/mii-pr-seltene-icf-assessment: StructureDefinition.snapshot.element[0].constraint[8]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 339836
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "FHIRPATH_COLLECTION_STATUS_OPERATION_LEFT"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "mii-icf-2: The left side is inherently a collection, and so the expression 'code.coding.code != 'nature-of-change'' may fail or return false if there is more than one item in the content being evaluated"
            },
            "expression": [
              "StructureDefinition/mii-pr-seltene-icf-assessment: StructureDefinition.snapshot.element[0].constraint[8]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 339836
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "FHIRPATH_COLLECTION_STATUS_OPERATION_LEFT"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "mii-icf-2: The left side is inherently a collection, and so the expression 'code.coding.code != 'anatomical-location'' may fail or return false if there is more than one item in the content being evaluated"
            },
            "expression": [
              "StructureDefinition/mii-pr-seltene-icf-assessment: StructureDefinition.snapshot.element[0].constraint[8]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 340292
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "FHIRPATH_COLLECTION_STATUS_OPERATION_LEFT"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "mii-icf-3: The left side is inherently a collection, and so the expression 'code.coding.code != 'capacity'' may fail or return false if there is more than one item in the content being evaluated"
            },
            "expression": [
              "StructureDefinition/mii-pr-seltene-icf-assessment: StructureDefinition.snapshot.element[0].constraint[9]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 340292
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "FHIRPATH_COLLECTION_STATUS_OPERATION_LEFT"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "mii-icf-3: The left side is inherently a collection, and so the expression 'code.coding.code != 'performance'' may fail or return false if there is more than one item in the content being evaluated"
            },
            "expression": [
              "StructureDefinition/mii-pr-seltene-icf-assessment: StructureDefinition.snapshot.element[0].constraint[9]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 340752
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "FHIRPATH_COLLECTION_STATUS_OPERATION_LEFT"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "mii-icf-4: The left side is inherently a collection, and so the expression 'code.coding.code != 'barrier'' may fail or return false if there is more than one item in the content being evaluated"
            },
            "expression": [
              "StructureDefinition/mii-pr-seltene-icf-assessment: StructureDefinition.snapshot.element[0].constraint[10]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 340752
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "FHIRPATH_COLLECTION_STATUS_OPERATION_LEFT"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "mii-icf-4: The left side is inherently a collection, and so the expression 'code.coding.code != 'facilitator'' may fail or return false if there is more than one item in the content being evaluated"
            },
            "expression": [
              "StructureDefinition/mii-pr-seltene-icf-assessment: StructureDefinition.snapshot.element[0].constraint[10]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 341148
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "FHIRPATH_COLLECTION_STATUS_OPERATION_LEFT"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "mii-icf-5: The left side is inherently a collection, and so the expression 'code.coding.code = 'barrier'' may fail or return false if there is more than one item in the content being evaluated"
            },
            "expression": [
              "StructureDefinition/mii-pr-seltene-icf-assessment: StructureDefinition.snapshot.element[0].constraint[11]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 341148
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "FHIRPATH_COLLECTION_STATUS_OPERATION_LEFT"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "mii-icf-5: The left side is inherently a collection, and so the expression 'code.coding.code = 'facilitator'' may fail or return false if there is more than one item in the content being evaluated"
            },
            "expression": [
              "StructureDefinition/mii-pr-seltene-icf-assessment: StructureDefinition.snapshot.element[0].constraint[11]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "SD_ED_BIND_UNKNOWN_VS"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The valueSet reference https://terminologien.bfarm.de/fhir/ValueSet/icf-q-ausmass-der-schaedigung on element Observation.component.value[x] could not be resolved"
            },
            "expression": [
              "StructureDefinition/mii-pr-seltene-icf-assessment: StructureDefinition.snapshot.element[75].binding"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "SD_ED_BIND_UNKNOWN_VS"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The valueSet reference https://terminologien.bfarm.de/fhir/ValueSet/icf-q-ausmass-der-schaedigung-s on element Observation.component.value[x] could not be resolved"
            },
            "expression": [
              "StructureDefinition/mii-pr-seltene-icf-assessment: StructureDefinition.snapshot.element[84].binding"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "SD_ED_BIND_UNKNOWN_VS"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The valueSet reference https://terminologien.bfarm.de/fhir/ValueSet/icf-q-art-oder-veraenderung-in-der-entsprechenden-koerperstruktur on element Observation.component.value[x] could not be resolved"
            },
            "expression": [
              "StructureDefinition/mii-pr-seltene-icf-assessment: StructureDefinition.snapshot.element[93].binding"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "SD_ED_BIND_UNKNOWN_VS"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The valueSet reference https://terminologien.bfarm.de/fhir/ValueSet/icf-q-anatomische-lokalisation on element Observation.component.value[x] could not be resolved"
            },
            "expression": [
              "StructureDefinition/mii-pr-seltene-icf-assessment: StructureDefinition.snapshot.element[102].binding"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "SD_ED_BIND_UNKNOWN_VS"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The valueSet reference https://terminologien.bfarm.de/fhir/ValueSet/icf-q-leistungsfaehigkeit-und-leistung on element Observation.component.value[x] could not be resolved"
            },
            "expression": [
              "StructureDefinition/mii-pr-seltene-icf-assessment: StructureDefinition.snapshot.element[111].binding"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "SD_ED_BIND_UNKNOWN_VS"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The valueSet reference https://terminologien.bfarm.de/fhir/ValueSet/icf-q-leistungsfaehigkeit-und-leistung on element Observation.component.value[x] could not be resolved"
            },
            "expression": [
              "StructureDefinition/mii-pr-seltene-icf-assessment: StructureDefinition.snapshot.element[120].binding"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "SD_ED_BIND_UNKNOWN_VS"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The valueSet reference https://terminologien.bfarm.de/fhir/ValueSet/icf-q-barrieren on element Observation.component.value[x] could not be resolved"
            },
            "expression": [
              "StructureDefinition/mii-pr-seltene-icf-assessment: StructureDefinition.snapshot.element[129].binding"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "SD_ED_BIND_UNKNOWN_VS"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The valueSet reference https://terminologien.bfarm.de/fhir/ValueSet/icf-q-foerderfaktoren on element Observation.component.value[x] could not be resolved"
            },
            "expression": [
              "StructureDefinition/mii-pr-seltene-icf-assessment: StructureDefinition.snapshot.element[138].binding"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/OperationOutcome/StructureDefinition-mii-pr-seltene-kopfumfang",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "StructureDefinition-mii-pr-seltene-kopfumfang",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 49726
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "StructureDefinition/mii-pr-seltene-kopfumfang: StructureDefinition.jurisdiction[0].coding[0].system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/OperationOutcome/StructureDefinition-mii-pr-seltene-registerteilnahme",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "StructureDefinition-mii-pr-seltene-registerteilnahme",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 55600
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "StructureDefinition/mii-pr-seltene-registerteilnahme: StructureDefinition.jurisdiction[0].coding[0].system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/OperationOutcome/StructureDefinition-mii-pr-seltene-studieneinschluss-anfrage",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "StructureDefinition-mii-pr-seltene-studieneinschluss-anfrage",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 108904
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "StructureDefinition/mii-pr-seltene-studieneinschluss-anfrage: StructureDefinition.jurisdiction[0].coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 121831
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TYPE_SPECIFIC_CHECKS_DT_CANONICAL_MULTIPLE_POSSIBLE_VERSIONS"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "There are multiple different potential matches for the url 'http://hl7.org/fhir/StructureDefinition/request-statusReason'. It might be a good idea to fix to the correct version to reduce the likelihood of a wrong version being selected by an implementation/implementer, or use the [IG Parameter `pin-canonicals`](https://hl7.org/fhir/tools/CodeSystem-ig-parameters.html). Using version '5.3.0', found versions: 4.0.1 (from hl7.fhir.r4.core#4.0.1), 5.1.0 (from hl7.fhir.uv.extensions.r4#5.1.0), 5.2.0 (from hl7.fhir.uv.extensions.r4#5.2.0), 5.3.0 (from hl7.fhir.uv.extensions.r4#5.3.0). Suggested fix: change the canonical reference from 'http://hl7.org/fhir/StructureDefinition/request-statusReason' to 'http://hl7.org/fhir/StructureDefinition/request-statusReason|5.3.0'"
            },
            "expression": [
              "StructureDefinition/mii-pr-seltene-studieneinschluss-anfrage: StructureDefinition.snapshot.element[8].type[0].profile[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 180892
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TYPE_SPECIFIC_CHECKS_DT_CANONICAL_MULTIPLE_POSSIBLE_VERSIONS"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "There are multiple different potential matches for the url 'http://hl7.org/fhir/StructureDefinition/request-statusReason'. It might be a good idea to fix to the correct version to reduce the likelihood of a wrong version being selected by an implementation/implementer, or use the [IG Parameter `pin-canonicals`](https://hl7.org/fhir/tools/CodeSystem-ig-parameters.html). Using version '5.3.0', found versions: 4.0.1 (from hl7.fhir.r4.core#4.0.1), 5.1.0 (from hl7.fhir.uv.extensions.r4#5.1.0), 5.2.0 (from hl7.fhir.uv.extensions.r4#5.2.0), 5.3.0 (from hl7.fhir.uv.extensions.r4#5.3.0). Suggested fix: change the canonical reference from 'http://hl7.org/fhir/StructureDefinition/request-statusReason' to 'http://hl7.org/fhir/StructureDefinition/request-statusReason|5.3.0'"
            },
            "expression": [
              "StructureDefinition/mii-pr-seltene-studieneinschluss-anfrage: StructureDefinition.differential.element[2].type[0].profile[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "SD_VALUE_COMPLEX_FIXED"
              }
            ],
            "severity": "warning",
            "code": "exception",
            "details": {
              "text": "For the complex type CodeableConcept, consider using a pattern rather than a fixed value to avoid over-constraining the instance"
            },
            "expression": [
              "StructureDefinition/mii-pr-seltene-studieneinschluss-anfrage: StructureDefinition.snapshot.element[28].fixed.ofType(CodeableConcept)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "SD_VALUE_COMPLEX_FIXED"
              }
            ],
            "severity": "warning",
            "code": "exception",
            "details": {
              "text": "For the complex type CodeableConcept, consider using a pattern rather than a fixed value to avoid over-constraining the instance"
            },
            "expression": [
              "StructureDefinition/mii-pr-seltene-studieneinschluss-anfrage: StructureDefinition.snapshot.element[31].fixed.ofType(CodeableConcept)"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/OperationOutcome/StructureDefinition-mii-pr-seltene-symptom-condition",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "StructureDefinition-mii-pr-seltene-symptom-condition",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 229822
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "StructureDefinition/mii-pr-seltene-symptom-condition: StructureDefinition.jurisdiction[0].coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 341413
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "The slice 'onsetDateTime' on path 'Condition.onset[x]' is not marked as 'must-support' which is not consistent with the element that defines the slicing, where 'must-support' is true"
            },
            "expression": [
              "StructureDefinition/mii-pr-seltene-symptom-condition: StructureDefinition.snapshot"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 341413
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "The slice 'onsetPeriod' on path 'Condition.onset[x]' is not marked as 'must-support' which is not consistent with the element that defines the slicing, where 'must-support' is true"
            },
            "expression": [
              "StructureDefinition/mii-pr-seltene-symptom-condition: StructureDefinition.snapshot"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 341413
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "The slice 'onsetAge' on path 'Condition.onset[x]' is not marked as 'must-support' which is not consistent with the element that defines the slicing, where 'must-support' is true"
            },
            "expression": [
              "StructureDefinition/mii-pr-seltene-symptom-condition: StructureDefinition.snapshot"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 341413
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "The slice 'onsetString' on path 'Condition.onset[x]' is not marked as 'must-support' which is not consistent with the element that defines the slicing, where 'must-support' is true"
            },
            "expression": [
              "StructureDefinition/mii-pr-seltene-symptom-condition: StructureDefinition.snapshot"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 341413
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "The slice 'abatementDateTime' on path 'Condition.abatement[x]' is not marked as 'must-support' which is not consistent with the element that defines the slicing, where 'must-support' is true"
            },
            "expression": [
              "StructureDefinition/mii-pr-seltene-symptom-condition: StructureDefinition.snapshot"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/OperationOutcome/StructureDefinition-mii-pr-seltene-taillenumfang",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "StructureDefinition-mii-pr-seltene-taillenumfang",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 87458
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "StructureDefinition/mii-pr-seltene-taillenumfang: StructureDefinition.jurisdiction[0].coding[0].system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/OperationOutcome/StructureDefinition-mii-pr-seltene-therapie-durchgefuehrt",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "StructureDefinition-mii-pr-seltene-therapie-durchgefuehrt",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 64567
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "StructureDefinition/mii-pr-seltene-therapie-durchgefuehrt: StructureDefinition.jurisdiction[0].coding[0].system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/OperationOutcome/StructureDefinition-mii-pr-seltene-therapieempfehlung-kombination",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "StructureDefinition-mii-pr-seltene-therapieempfehlung-kombination",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 65938
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "StructureDefinition/mii-pr-seltene-therapieempfehlung-kombination: StructureDefinition.jurisdiction[0].coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "Publisher"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The Implementation Guide contains no examples for this profile"
            },
            "expression": [
              "StructureDefinition.where(url = 'https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/StructureDefinition/mii-pr-seltene-therapieempfehlung-kombination')"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/OperationOutcome/StructureDefinition-mii-pr-seltene-therapieempfehlung-nicht-medikamentoes",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "StructureDefinition-mii-pr-seltene-therapieempfehlung-nicht-medikamentoes",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 176325
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "StructureDefinition/mii-pr-seltene-therapieempfehlung-nicht-medikamentoes: StructureDefinition.jurisdiction[0].coding[0].system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/OperationOutcome/StructureDefinition-mii-pr-seltene-therapieempfehlung",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "StructureDefinition-mii-pr-seltene-therapieempfehlung",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 92406
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "StructureDefinition/mii-pr-seltene-therapieempfehlung: StructureDefinition.jurisdiction[0].coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 345226
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TYPE_SPECIFIC_CHECKS_DT_CANONICAL_MULTIPLE_POSSIBLE_VERSIONS"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "There are multiple different potential matches for the url 'http://hl7.org/fhir/uv/ips/ValueSet/body-site-uv-ips'. It might be a good idea to fix to the correct version to reduce the likelihood of a wrong version being selected by an implementation/implementer, or use the [IG Parameter `pin-canonicals`](https://hl7.org/fhir/tools/CodeSystem-ig-parameters.html). Using version '2.0.1', found versions: 2.0.0 (from hl7.fhir.uv.ips#2.0.0), 2.0.1 (from hl7.fhir.uv.ips#2.0.1). Suggested fix: change the canonical reference from 'http://hl7.org/fhir/uv/ips/ValueSet/body-site-uv-ips' to 'http://hl7.org/fhir/uv/ips/ValueSet/body-site-uv-ips|2.0.1'"
            },
            "expression": [
              "StructureDefinition/mii-pr-seltene-therapieempfehlung: StructureDefinition.snapshot.element[178].binding.valueSet"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 363746
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TYPE_SPECIFIC_CHECKS_DT_CANONICAL_MULTIPLE_POSSIBLE_VERSIONS"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "There are multiple different potential matches for the url 'http://hl7.org/fhir/uv/ips/ValueSet/medicine-route-of-administration'. It might be a good idea to fix to the correct version to reduce the likelihood of a wrong version being selected by an implementation/implementer, or use the [IG Parameter `pin-canonicals`](https://hl7.org/fhir/tools/CodeSystem-ig-parameters.html). Using version '2.0.1', found versions: 2.0.0 (from hl7.fhir.uv.ips#2.0.0), 2.0.1 (from hl7.fhir.uv.ips#2.0.1). Suggested fix: change the canonical reference from 'http://hl7.org/fhir/uv/ips/ValueSet/medicine-route-of-administration' to 'http://hl7.org/fhir/uv/ips/ValueSet/medicine-route-of-administration|2.0.1'"
            },
            "expression": [
              "StructureDefinition/mii-pr-seltene-therapieempfehlung: StructureDefinition.snapshot.element[191].binding.valueSet"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/OperationOutcome/StructureDefinition-mii-pr-seltene-therapieplan",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "StructureDefinition-mii-pr-seltene-therapieplan",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 90478
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "StructureDefinition/mii-pr-seltene-therapieplan: StructureDefinition.jurisdiction[0].coding[0].system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/OperationOutcome/ValueSet-mii-vs-seltene-blutgruppe",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ValueSet-mii-vs-seltene-blutgruppe",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 9739
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablevalueset|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-blutgruppe: ValueSet.jurisdiction[0].coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 9880
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'LA21322-5' is not valid in the system http://loinc.org (error: [96f699b4-c160-4546-a774-3b85d10f18f7]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-blutgruppe: ValueSet.compose.include[0].concept[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 9919
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'LA21327-4' is not valid in the system http://loinc.org (error: [7744db65-7a3a-4a10-b166-1458b350c9a2]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-blutgruppe: ValueSet.compose.include[0].concept[2]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 9958
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'LA21328-2' is not valid in the system http://loinc.org (error: [8ec1e82b-7b34-42f6-b314-a93410761981]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-blutgruppe: ValueSet.compose.include[0].concept[3]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 9998
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'LA21323-3' is not valid in the system http://loinc.org (error: [9a4033d0-84cf-4d28-969d-ab128a426326]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-blutgruppe: ValueSet.compose.include[0].concept[4]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10038
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'LA21324-1' is not valid in the system http://loinc.org (error: [a5ed41f3-a8bb-4a8b-998a-ec4beb73a500]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-blutgruppe: ValueSet.compose.include[0].concept[5]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10077
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'LA21325-8' is not valid in the system http://loinc.org (error: [098fd9bf-fc03-4d44-af4b-c3d2bd75ed0e]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-blutgruppe: ValueSet.compose.include[0].concept[6]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10116
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'LA21326-6' is not valid in the system http://loinc.org (error: [d6788755-88d4-468d-ba72-ba90d0d54887]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-blutgruppe: ValueSet.compose.include[0].concept[7]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10308
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '278148006' is not valid in the system http://snomed.info/sct (error: [362d2793-c227-4516-974f-299c304d6fdc]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-blutgruppe: ValueSet.compose.include[1].concept[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10380
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '278150003' is not valid in the system http://snomed.info/sct (error: [81d000cb-7dfa-4f21-a7bd-62292c8ec27c]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-blutgruppe: ValueSet.compose.include[1].concept[2]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10452
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '278153001' is not valid in the system http://snomed.info/sct (error: [5d86a224-8b96-4f1d-a57b-1deee627f42a]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-blutgruppe: ValueSet.compose.include[1].concept[3]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10525
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '278151004' is not valid in the system http://snomed.info/sct (error: [31ae33c8-6de7-4ca8-bc1c-b82137eb4415]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-blutgruppe: ValueSet.compose.include[1].concept[4]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10598
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '278154007' is not valid in the system http://snomed.info/sct (error: [3c4e130f-600f-47d1-bf05-0425c0fbc011]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-blutgruppe: ValueSet.compose.include[1].concept[5]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10670
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '278149003' is not valid in the system http://snomed.info/sct (error: [c587f1a3-e477-4a3e-b3f7-e86e9387210d]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-blutgruppe: ValueSet.compose.include[1].concept[6]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10742
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '278152006' is not valid in the system http://snomed.info/sct (error: [a364ed2e-3200-4667-ab18-d5e3d95e6d86]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-blutgruppe: ValueSet.compose.include[1].concept[7]"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/OperationOutcome/ValueSet-mii-vs-seltene-clinical-diagnosis-category",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ValueSet-mii-vs-seltene-clinical-diagnosis-category",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 7092
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablevalueset|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-clinical-diagnosis-category: ValueSet.jurisdiction[0].coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 7254
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '404684003' is not valid in the system http://snomed.info/sct (error: [2f226073-c721-41fd-bc8f-e7a8e6bf930f]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-clinical-diagnosis-category: ValueSet.compose.include[0].concept[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 7294
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '64572001' is not valid in the system http://snomed.info/sct (error: [4a5891f4-8107-440c-98c5-5e1da864a4a2]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-clinical-diagnosis-category: ValueSet.compose.include[0].concept[2]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 7345
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '66091009' is not valid in the system http://snomed.info/sct (error: [f445af91-e625-4835-b0fe-fc1bce843eb5]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-clinical-diagnosis-category: ValueSet.compose.include[0].concept[3]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 7399
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '609328004' is not valid in the system http://snomed.info/sct (error: [49dedfcc-3abc-4abd-903a-e7479963cdf9]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-clinical-diagnosis-category: ValueSet.compose.include[0].concept[4]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 7450
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '85828009' is not valid in the system http://snomed.info/sct (error: [286833ca-0383-4593-8aed-ec84e362783e]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-clinical-diagnosis-category: ValueSet.compose.include[0].concept[5]"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/OperationOutcome/ValueSet-mii-vs-seltene-consanguinity",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ValueSet-mii-vs-seltene-consanguinity",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 6418
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablevalueset|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-consanguinity: ValueSet.jurisdiction[0].coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 6560
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '373067005' is not valid in the system http://snomed.info/sct (error: [9493ec2b-7ef3-4a70-900c-0c04808482bb]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-consanguinity: ValueSet.compose.include[0].concept[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 6601
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '261665006' is not valid in the system http://snomed.info/sct (error: [298ef045-33fb-4a3f-a539-287551ed350a]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-consanguinity: ValueSet.compose.include[0].concept[2]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 6648
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '1220561009' is not valid in the system http://snomed.info/sct (error: [5f016273-2f22-4207-a776-2ea184b05f42]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-consanguinity: ValueSet.compose.include[0].concept[3]"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/OperationOutcome/ValueSet-mii-vs-seltene-empfehlung-status-begruendung",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ValueSet-mii-vs-seltene-empfehlung-status-begruendung",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 5778
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablevalueset|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-empfehlung-status-begruendung: ValueSet.jurisdiction[0].coding[0].system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/OperationOutcome/ValueSet-mii-vs-seltene-genetic-basis",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ValueSet-mii-vs-seltene-genetic-basis",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 7721
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablevalueset|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-genetic-basis: ValueSet.jurisdiction[0].coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 7898
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '264530000' is not valid in the system http://snomed.info/sct (error: [a8faf2ba-a6b4-4eed-9bf3-5ff7f03cd739]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-genetic-basis: ValueSet.compose.include[0].concept[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 7953
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '16402000' is not valid in the system http://snomed.info/sct (error: [3c368aef-4021-47ba-8ed5-5646956df4b1]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-genetic-basis: ValueSet.compose.include[0].concept[2]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8005
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '268298002' is not valid in the system http://snomed.info/sct (error: [f130106c-06f7-41e9-ab0c-c0eec84d94c9]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-genetic-basis: ValueSet.compose.include[0].concept[3]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8076
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '429962007' is not valid in the system http://snomed.info/sct (error: [effc7cdc-98c4-4fc3-b39d-d7d1564c5ed7]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-genetic-basis: ValueSet.compose.include[0].concept[4]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8162
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '718211000119104' is not valid in the system http://snomed.info/sct (error: [5db644cd-d494-4b2b-8ab3-a01d89e26965]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-genetic-basis: ValueSet.compose.include[0].concept[5]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8230
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '416010008' is not valid in the system http://snomed.info/sct (error: [fc723faa-eb97-4f42-957e-4bc87131df51]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-genetic-basis: ValueSet.compose.include[0].concept[6]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8298
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '429252008' is not valid in the system http://snomed.info/sct (error: [33e89eb2-8366-48c4-8a67-8d028628001d]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-genetic-basis: ValueSet.compose.include[0].concept[7]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8355
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '363235000' is not valid in the system http://snomed.info/sct (error: [7a88f14f-ed4f-4b7c-b5f9-109d33da275b]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-genetic-basis: ValueSet.compose.include[0].concept[8]"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/OperationOutcome/ValueSet-mii-vs-seltene-hpo-age-of-onset",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ValueSet-mii-vs-seltene-hpo-age-of-onset",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 7692
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablevalueset|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-hpo-age-of-onset: ValueSet.jurisdiction[0].coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 7986
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'HP:0011461' is not valid in the system http://human-phenotype-ontology.org (error: [764f3ec2-0083-4768-ab52-7cc44a67fde1]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-hpo-age-of-onset: ValueSet.compose.include[1].concept[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8037
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'HP:0003577' is not valid in the system http://human-phenotype-ontology.org (error: [ab5b4423-0ada-4d65-a82c-203450d2785d]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-hpo-age-of-onset: ValueSet.compose.include[1].concept[2]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8086
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'HP:0003623' is not valid in the system http://human-phenotype-ontology.org (error: [00320171-efe6-4f86-9efd-8470ec4d7c86]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-hpo-age-of-onset: ValueSet.compose.include[1].concept[3]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8136
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'HP:0003593' is not valid in the system http://human-phenotype-ontology.org (error: [a77fb78b-82ab-406c-973d-cf16bbc892a4]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-hpo-age-of-onset: ValueSet.compose.include[1].concept[4]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8186
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'HP:0011463' is not valid in the system http://human-phenotype-ontology.org (error: [584228ad-0ddf-4c01-9fba-194b5573a8ae]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-hpo-age-of-onset: ValueSet.compose.include[1].concept[5]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8235
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'HP:0003621' is not valid in the system http://human-phenotype-ontology.org (error: [2f13a99f-f552-414e-80bc-1c6ff0fdf1ff]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-hpo-age-of-onset: ValueSet.compose.include[1].concept[6]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8287
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'HP:0011462' is not valid in the system http://human-phenotype-ontology.org (error: [b62de15e-88d2-4b5d-a667-3418e9bbd6a1]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-hpo-age-of-onset: ValueSet.compose.include[1].concept[7]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8345
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'HP:0025708' is not valid in the system http://human-phenotype-ontology.org (error: [7ebfcefb-f44c-4680-b356-a169449c368a]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-hpo-age-of-onset: ValueSet.compose.include[1].concept[8]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8391
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'HP:0003581' is not valid in the system http://human-phenotype-ontology.org (error: [c2cb6444-039d-40a7-81e2-bcb7db85750f]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-hpo-age-of-onset: ValueSet.compose.include[1].concept[9]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8442
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'HP:0003596' is not valid in the system http://human-phenotype-ontology.org (error: [87faec33-d902-4764-811d-e15a893e4cc2]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-hpo-age-of-onset: ValueSet.compose.include[1].concept[10]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8487
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'HP:0003584' is not valid in the system http://human-phenotype-ontology.org (error: [3f52a711-9883-4d03-bea1-0e059c1122de]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-hpo-age-of-onset: ValueSet.compose.include[1].concept[11]"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/OperationOutcome/ValueSet-mii-vs-seltene-hpo-change-status",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ValueSet-mii-vs-seltene-hpo-change-status",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 5668
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablevalueset|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-hpo-change-status: ValueSet.jurisdiction[0].coding[0].system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/OperationOutcome/ValueSet-mii-vs-seltene-hpo-inheritance-pattern",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ValueSet-mii-vs-seltene-hpo-inheritance-pattern",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8267
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablevalueset|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-hpo-inheritance-pattern: ValueSet.jurisdiction[0].coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8596
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'HP:0000007' is not valid in the system http://human-phenotype-ontology.org (error: [65e79928-e175-4974-9f7c-a654df02eeca]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-hpo-inheritance-pattern: ValueSet.compose.include[1].concept[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8651
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'HP:0001417' is not valid in the system http://human-phenotype-ontology.org (error: [b57a32fe-c045-4a23-9848-1f3047019740]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-hpo-inheritance-pattern: ValueSet.compose.include[1].concept[2]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8716
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'HP:0001419' is not valid in the system http://human-phenotype-ontology.org (error: [2a6d8259-b0d2-4c89-bf21-d8977036a412]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-hpo-inheritance-pattern: ValueSet.compose.include[1].concept[3]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8780
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'HP:0001423' is not valid in the system http://human-phenotype-ontology.org (error: [cd329c32-059d-43a2-aac4-8dc0ea120f6f]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-hpo-inheritance-pattern: ValueSet.compose.include[1].concept[4]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8840
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'HP:0001427' is not valid in the system http://human-phenotype-ontology.org (error: [3a2c754c-b813-4ba7-8fc2-6a92fc80eb25]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-hpo-inheritance-pattern: ValueSet.compose.include[1].concept[5]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8904
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'HP:0001428' is not valid in the system http://human-phenotype-ontology.org (error: [3459bd44-514e-4c81-b8c2-8c8724dac458]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-hpo-inheritance-pattern: ValueSet.compose.include[1].concept[6]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8947
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'HP:0003745' is not valid in the system http://human-phenotype-ontology.org (error: [9fe11514-e215-4142-bcda-b6198463b7c3]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-hpo-inheritance-pattern: ValueSet.compose.include[1].concept[7]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 9004
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'HP:0010983' is not valid in the system http://human-phenotype-ontology.org (error: [f5317700-4585-407d-947d-9fbb3a35cc2a]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-hpo-inheritance-pattern: ValueSet.compose.include[1].concept[8]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 9060
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'HP:0010982' is not valid in the system http://human-phenotype-ontology.org (error: [a16106a7-6dda-41b7-b70e-6489cb3b9414]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-hpo-inheritance-pattern: ValueSet.compose.include[1].concept[9]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 9120
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'HP:0001426' is not valid in the system http://human-phenotype-ontology.org (error: [c244ae1d-9724-451e-9310-bdc286f34532]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-hpo-inheritance-pattern: ValueSet.compose.include[1].concept[10]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 9210
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'HP:0012275' is not valid in the system http://human-phenotype-ontology.org (error: [69920189-0eb6-4a2e-b2a2-7adba45892aa]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-hpo-inheritance-pattern: ValueSet.compose.include[1].concept[11]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 9300
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'HP:0012274' is not valid in the system http://human-phenotype-ontology.org (error: [dcb265b1-29ec-498d-9c72-5357f5a34f03]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-hpo-inheritance-pattern: ValueSet.compose.include[1].concept[12]"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/OperationOutcome/ValueSet-mii-vs-seltene-hpo-phenotypic-observation-codes",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ValueSet-mii-vs-seltene-hpo-phenotypic-observation-codes",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 5583
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablevalueset|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-hpo-phenotypic-observation-codes: ValueSet.jurisdiction[0].coding[0].system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/OperationOutcome/ValueSet-mii-vs-seltene-hpo-presence-status",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ValueSet-mii-vs-seltene-hpo-presence-status",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 5974
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablevalueset|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-hpo-presence-status: ValueSet.jurisdiction[0].coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 6225
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'LA9634-2' is not valid in the system http://loinc.org (error: [be203e8d-d1ed-4f55-a6e8-cd99b40a9a27]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-hpo-presence-status: ValueSet.compose.include[0].concept[1]"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/OperationOutcome/ValueSet-mii-vs-seltene-hpo-severity",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ValueSet-mii-vs-seltene-hpo-severity",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 6107
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablevalueset|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-hpo-severity: ValueSet.jurisdiction[0].coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 6352
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'HP:0012825' is not valid in the system http://human-phenotype-ontology.org (error: [cf9bd268-f478-4d0e-87a9-49b45470acae]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-hpo-severity: ValueSet.compose.include[0].concept[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 6395
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'HP:0012826' is not valid in the system http://human-phenotype-ontology.org (error: [f018ad1f-80af-47ca-ab11-14b053daa4fc]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-hpo-severity: ValueSet.compose.include[0].concept[2]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 6438
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'HP:0012829' is not valid in the system http://human-phenotype-ontology.org (error: [289542ee-7502-4c27-bee4-00add4c06d28]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-hpo-severity: ValueSet.compose.include[0].concept[3]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 6483
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'HP:0012827' is not valid in the system http://human-phenotype-ontology.org (error: [5003cb09-0a28-4dc3-ac4f-3f675661a22f]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-hpo-severity: ValueSet.compose.include[0].concept[4]"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/OperationOutcome/ValueSet-mii-vs-seltene-icf-beurteilungsmerkmal",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ValueSet-mii-vs-seltene-icf-beurteilungsmerkmal",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 5719
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablevalueset|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-icf-beurteilungsmerkmal: ValueSet.jurisdiction[0].coding[0].system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/OperationOutcome/ValueSet-mii-vs-seltene-icf",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ValueSet-mii-vs-seltene-icf",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 5648
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablevalueset|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-icf: ValueSet.jurisdiction[0].coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              }
            ],
            "severity": "warning",
            "code": "exception",
            "details": {
              "text": "Error from http://127.0.0.1:8090/fhir: Error: [1f690916-b959-461d-bf35-b8cbbd4e1337]: A usable code system with URL http://hl7.org/fhir/sid/icf could not be resolved.\r\nInformation: X-Request-Id: b2e08ee3-b6ef-4dd5-810e-59c3caa2471b"
            },
            "expression": [
              "ValueSet.where(id = 'mii-vs-seltene-icf')"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              }
            ],
            "severity": "warning",
            "code": "exception",
            "details": {
              "text": "Error from http://127.0.0.1:8090/fhir: Error: [1f690916-b959-461d-bf35-b8cbbd4e1337]: A usable code system with URL http://hl7.org/fhir/sid/icf could not be resolved.\r\nInformation: X-Request-Id: b2e08ee3-b6ef-4dd5-810e-59c3caa2471b"
            },
            "expression": [
              "ValueSet.where(id = 'mii-vs-seltene-icf')"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              }
            ],
            "severity": "warning",
            "code": "exception",
            "details": {
              "text": "Error from http://127.0.0.1:8090/fhir: Error: [1f690916-b959-461d-bf35-b8cbbd4e1337]: A usable code system with URL http://hl7.org/fhir/sid/icf could not be resolved.\r\nInformation: X-Request-Id: b2e08ee3-b6ef-4dd5-810e-59c3caa2471b"
            },
            "expression": [
              "ValueSet.where(id = 'mii-vs-seltene-icf')"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/OperationOutcome/ValueSet-mii-vs-seltene-narse-therapietyp",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ValueSet-mii-vs-seltene-narse-therapietyp",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 5652
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablevalueset|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-narse-therapietyp: ValueSet.jurisdiction[0].coding[0].system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/OperationOutcome/ValueSet-mii-vs-seltene-nbs-acylcarnitine-dbs",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ValueSet-mii-vs-seltene-nbs-acylcarnitine-dbs",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 26892
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablevalueset|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-acylcarnitine-dbs: ValueSet.jurisdiction[0].coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 27133
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '53189-7' is not valid in the system http://loinc.org (error: [56543aa6-67f8-4b28-8c03-10124b266818]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-acylcarnitine-dbs: ValueSet.compose.include[0].concept[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 27221
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '53173-1' is not valid in the system http://loinc.org (error: [e6c85724-586a-4c90-8ac2-ff5c1f41feb8]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-acylcarnitine-dbs: ValueSet.compose.include[0].concept[2]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 27311
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '50106-4' is not valid in the system http://loinc.org (error: [cf839717-f6c7-4218-89a9-ebe43d016090]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-acylcarnitine-dbs: ValueSet.compose.include[0].concept[3]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 27420
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '53171-5' is not valid in the system http://loinc.org (error: [a4b2c45c-502b-4420-9828-8f1692357575]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-acylcarnitine-dbs: ValueSet.compose.include[0].concept[4]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 27532
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '53172-3' is not valid in the system http://loinc.org (error: [18f800db-0f1b-46b0-b9e2-9811081447a2]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-acylcarnitine-dbs: ValueSet.compose.include[0].concept[5]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 27624
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '50109-8' is not valid in the system http://loinc.org (error: [e0a74ecc-c930-4979-8b60-05737967d8d2]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-acylcarnitine-dbs: ValueSet.compose.include[0].concept[6]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 27713
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '50113-0' is not valid in the system http://loinc.org (error: [1744b6e7-201e-443a-a38f-59d92410a4bd]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-acylcarnitine-dbs: ValueSet.compose.include[0].concept[7]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 27807
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '50121-3' is not valid in the system http://loinc.org (error: [1fd3da6e-ab5a-4801-8ae6-4d539e3f675d]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-acylcarnitine-dbs: ValueSet.compose.include[0].concept[8]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 27897
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '50125-4' is not valid in the system http://loinc.org (error: [6eac1066-e3a4-425c-8c94-cd40801d7385]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-acylcarnitine-dbs: ValueSet.compose.include[0].concept[9]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 28011
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '53201-0' is not valid in the system http://loinc.org (error: [cf0df736-3170-4318-8c96-447459cb0eef]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-acylcarnitine-dbs: ValueSet.compose.include[0].concept[10]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 28100
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '50132-0' is not valid in the system http://loinc.org (error: [1d58113d-0bf9-4d0a-be50-63702aa6730c]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-acylcarnitine-dbs: ValueSet.compose.include[0].concept[11]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 28199
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '53196-2' is not valid in the system http://loinc.org (error: [c39bfc0b-1d25-4223-9663-f6f93df3c20e]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-acylcarnitine-dbs: ValueSet.compose.include[0].concept[12]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 28293
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '50281-5' is not valid in the system http://loinc.org (error: [5848e1da-8735-4037-bb34-7d40568b7a9f]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-acylcarnitine-dbs: ValueSet.compose.include[0].concept[13]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 28389
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '53197-0' is not valid in the system http://loinc.org (error: [46600e28-1949-4688-92e1-de166f78b5bc]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-acylcarnitine-dbs: ValueSet.compose.include[0].concept[14]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 28463
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '50157-7' is not valid in the system http://loinc.org (error: [00d9f54e-79c4-431b-95a9-d48d07674fe8]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-acylcarnitine-dbs: ValueSet.compose.include[0].concept[15]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 28540
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '53237-4' is not valid in the system http://loinc.org (error: [b21e90eb-3572-47a4-943d-ecedc9310355]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-acylcarnitine-dbs: ValueSet.compose.include[0].concept[16]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 28607
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '38474-3' is not valid in the system http://loinc.org (error: [29175425-dbcf-4d63-b689-9c1fab0079ed]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-acylcarnitine-dbs: ValueSet.compose.include[0].concept[17]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 28670
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '43717-8' is not valid in the system http://loinc.org (error: [13458b96-f7a6-423b-b086-cfcc942ce18d]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-acylcarnitine-dbs: ValueSet.compose.include[0].concept[18]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 28748
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '74628-9' is not valid in the system http://loinc.org (error: [255c497d-c5d0-46a3-bfe9-bd8846fe2bf8]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-acylcarnitine-dbs: ValueSet.compose.include[0].concept[19]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 28825
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '53613-6' is not valid in the system http://loinc.org (error: [f8460fe8-999f-43b1-aa55-b2ec10f34f6b]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-acylcarnitine-dbs: ValueSet.compose.include[0].concept[20]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 28900
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '53065-9' is not valid in the system http://loinc.org (error: [607cd61e-1049-4f5a-a8b9-67e47f177304]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-acylcarnitine-dbs: ValueSet.compose.include[0].concept[21]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 28982
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '53180-6' is not valid in the system http://loinc.org (error: [c54ef453-23fe-4cf7-ae89-d6be8e52edd1]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-acylcarnitine-dbs: ValueSet.compose.include[0].concept[22]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 29059
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '45197-1' is not valid in the system http://loinc.org (error: [2246f5ea-ecb9-4aca-be8f-e2cce13802e2]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-acylcarnitine-dbs: ValueSet.compose.include[0].concept[23]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 29138
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '45198-9' is not valid in the system http://loinc.org (error: [f6cafc02-98a2-4d23-8c21-81700e9dd679]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-acylcarnitine-dbs: ValueSet.compose.include[0].concept[24]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 29229
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '53214-3' is not valid in the system http://loinc.org (error: [935fcee2-17e3-4c35-8480-0bdf96e88fa7]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-acylcarnitine-dbs: ValueSet.compose.include[0].concept[25]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 29322
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '53213-5' is not valid in the system http://loinc.org (error: [ed1ca68d-6680-46fe-ab9f-4f7ec8162bde]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-acylcarnitine-dbs: ValueSet.compose.include[0].concept[26]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 29412
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '53218-4' is not valid in the system http://loinc.org (error: [4dc6fa98-4cc2-48a6-8085-bff0e0cacd52]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-acylcarnitine-dbs: ValueSet.compose.include[0].concept[27]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 29501
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '53220-0' is not valid in the system http://loinc.org (error: [3bf24e5f-86c0-4bdc-b7ea-f68d50783058]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-acylcarnitine-dbs: ValueSet.compose.include[0].concept[28]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 29589
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '53219-2' is not valid in the system http://loinc.org (error: [4675f6ed-7d60-42cc-83b4-908687635fce]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-acylcarnitine-dbs: ValueSet.compose.include[0].concept[29]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 29683
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '53216-8' is not valid in the system http://loinc.org (error: [3eca7078-4cfa-417d-87f5-2b83c4073eae]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-acylcarnitine-dbs: ValueSet.compose.include[0].concept[30]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 29779
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '53215-0' is not valid in the system http://loinc.org (error: [0121273c-69fe-4a95-8aa3-0ff241bd42ac]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-acylcarnitine-dbs: ValueSet.compose.include[0].concept[31]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 29858
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '45199-7' is not valid in the system http://loinc.org (error: [c13f4729-48ff-49ec-98ea-4e7a3f2ff9db]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-acylcarnitine-dbs: ValueSet.compose.include[0].concept[32]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 29939
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '45200-3' is not valid in the system http://loinc.org (error: [172efc26-4352-485f-9423-b78203e5733f]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-acylcarnitine-dbs: ValueSet.compose.include[0].concept[33]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 30018
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '53462-8' is not valid in the system http://loinc.org (error: [c2168442-c4ba-493e-b767-3e32986ff1d0]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-acylcarnitine-dbs: ValueSet.compose.include[0].concept[34]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 30097
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '45207-8' is not valid in the system http://loinc.org (error: [76683b58-f8fc-4b34-a540-3e93cee0854c]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-acylcarnitine-dbs: ValueSet.compose.include[0].concept[35]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 30196
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '88016-1' is not valid in the system http://loinc.org (error: [aa8bac2d-a544-4b5f-8be5-e8ea2b8fa182]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-acylcarnitine-dbs: ValueSet.compose.include[0].concept[36]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 30289
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '75225-3' is not valid in the system http://loinc.org (error: [deae1e7c-86fb-41c2-984c-8b34bb4f0de1]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-acylcarnitine-dbs: ValueSet.compose.include[0].concept[37]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 30392
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '75216-2' is not valid in the system http://loinc.org (error: [7e97320d-7792-4f77-b436-686508ac8c25]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-acylcarnitine-dbs: ValueSet.compose.include[0].concept[38]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 30495
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '75267-5' is not valid in the system http://loinc.org (error: [abeef90d-76c9-4dc5-bbe7-d776d4df0437]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-acylcarnitine-dbs: ValueSet.compose.include[0].concept[39]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 30597
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '88017-9' is not valid in the system http://loinc.org (error: [ba3d3f00-cf6e-4851-a850-e12e4214f1f8]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-acylcarnitine-dbs: ValueSet.compose.include[0].concept[40]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 30674
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '53204-4' is not valid in the system http://loinc.org (error: [1b9ebc27-b539-4a29-8eaa-dfa5575a3156]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-acylcarnitine-dbs: ValueSet.compose.include[0].concept[41]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 30750
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '45211-0' is not valid in the system http://loinc.org (error: [bb9eee37-ba85-4111-88db-51f044879114]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-acylcarnitine-dbs: ValueSet.compose.include[0].concept[42]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 30828
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '45213-6' is not valid in the system http://loinc.org (error: [faecee09-320c-445e-a5af-803cd859e59c]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-acylcarnitine-dbs: ValueSet.compose.include[0].concept[43]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 30906
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '42920-9' is not valid in the system http://loinc.org (error: [bb3cb62f-083c-4ce3-9310-d219e9e1d87a]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-acylcarnitine-dbs: ValueSet.compose.include[0].concept[44]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 30986
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '45217-7' is not valid in the system http://loinc.org (error: [29f5b8d8-21cc-4495-98c1-26a42e5a74a1]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-acylcarnitine-dbs: ValueSet.compose.include[0].concept[45]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 31064
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '54462-7' is not valid in the system http://loinc.org (error: [7f121192-f271-4aa8-a76a-e923aa8e5a73]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-acylcarnitine-dbs: ValueSet.compose.include[0].concept[46]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 31165
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '75212-1' is not valid in the system http://loinc.org (error: [2fbf36e7-c40d-43df-893a-2210f110136d]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-acylcarnitine-dbs: ValueSet.compose.include[0].concept[47]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 31249
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '45222-7' is not valid in the system http://loinc.org (error: [cd06b8c4-0c56-4e00-a785-48f5002aac43]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-acylcarnitine-dbs: ValueSet.compose.include[0].concept[48]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 31369
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '53181-4' is not valid in the system http://loinc.org (error: [268a9983-4f65-4fa2-a1ae-e1e5d89c724f]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-acylcarnitine-dbs: ValueSet.compose.include[0].concept[49]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 31445
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '53207-7' is not valid in the system http://loinc.org (error: [b1052d09-d19f-49b5-9385-5c0fe68dea4e]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-acylcarnitine-dbs: ValueSet.compose.include[0].concept[50]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 31521
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '53175-6' is not valid in the system http://loinc.org (error: [f75a4e5c-c057-4a45-8f18-e7f0323ee9d7]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-acylcarnitine-dbs: ValueSet.compose.include[0].concept[51]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 31617
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '53176-4' is not valid in the system http://loinc.org (error: [b9557a98-cf3f-4a21-8d21-d9a922b7bb82]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-acylcarnitine-dbs: ValueSet.compose.include[0].concept[52]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 31716
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '53177-2' is not valid in the system http://loinc.org (error: [61d786f3-f19b-45b7-961b-4e9df6682a3a]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-acylcarnitine-dbs: ValueSet.compose.include[0].concept[53]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 31811
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '88014-6' is not valid in the system http://loinc.org (error: [47b07a1f-5b19-4f69-bccc-6b8760351e8a]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-acylcarnitine-dbs: ValueSet.compose.include[0].concept[54]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 31889
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '53174-9' is not valid in the system http://loinc.org (error: [4d4191e5-35e4-494d-92e9-c6574a32bcd0]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-acylcarnitine-dbs: ValueSet.compose.include[0].concept[55]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 31966
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '53202-8' is not valid in the system http://loinc.org (error: [5a53d232-fb09-44f6-bd02-7bf3f4e422f1]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-acylcarnitine-dbs: ValueSet.compose.include[0].concept[56]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 32044
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '53199-6' is not valid in the system http://loinc.org (error: [7257bbb7-ab8f-4118-9372-28f94127ca0d]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-acylcarnitine-dbs: ValueSet.compose.include[0].concept[57]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 32142
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '88015-3' is not valid in the system http://loinc.org (error: [bccf6d83-e5e8-4887-8884-0d37537fb7b3]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-acylcarnitine-dbs: ValueSet.compose.include[0].concept[58]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 32239
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '88024-5' is not valid in the system http://loinc.org (error: [b7517aec-7fdb-43d3-b8bf-0d688cbe9e54]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-acylcarnitine-dbs: ValueSet.compose.include[0].concept[59]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 32318
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '54475-9' is not valid in the system http://loinc.org (error: [16bcb020-052b-4604-9009-621828403bd9]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-acylcarnitine-dbs: ValueSet.compose.include[0].concept[60]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 32395
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '53160-8' is not valid in the system http://loinc.org (error: [973f4ad6-07b5-47f5-a02d-fece2d570f38]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-acylcarnitine-dbs: ValueSet.compose.include[0].concept[61]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 32492
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '53163-2' is not valid in the system http://loinc.org (error: [907f8fc0-cc9a-4c5f-be61-f60034a890d2]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-acylcarnitine-dbs: ValueSet.compose.include[0].concept[62]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 32588
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '53162-4' is not valid in the system http://loinc.org (error: [66e0f5ca-4b9a-4c33-8459-de04b8eb3015]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-acylcarnitine-dbs: ValueSet.compose.include[0].concept[63]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 32689
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '53164-0' is not valid in the system http://loinc.org (error: [bbfa9bf2-e643-4b05-ae70-5577d789bd5b]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-acylcarnitine-dbs: ValueSet.compose.include[0].concept[64]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 32776
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '53161-6' is not valid in the system http://loinc.org (error: [3d844098-2e83-468f-94c3-6c07edfac2ba]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-acylcarnitine-dbs: ValueSet.compose.include[0].concept[65]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 32853
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '53241-6' is not valid in the system http://loinc.org (error: [d5e949b4-891f-4e66-a77a-ea2560081eb9]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-acylcarnitine-dbs: ValueSet.compose.include[0].concept[66]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 32953
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '53400-8' is not valid in the system http://loinc.org (error: [3685733e-f398-44eb-8dde-8c2dec25f127]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-acylcarnitine-dbs: ValueSet.compose.include[0].concept[67]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 33031
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '53210-1' is not valid in the system http://loinc.org (error: [a4f61428-4c5e-49a1-a525-f2737d232b38]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-acylcarnitine-dbs: ValueSet.compose.include[0].concept[68]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 33118
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '53190-5' is not valid in the system http://loinc.org (error: [6ceef6f7-f75e-4452-97f6-c6cca0c91dfc]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-acylcarnitine-dbs: ValueSet.compose.include[0].concept[69]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 33200
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '53192-1' is not valid in the system http://loinc.org (error: [008d574e-aeb3-4d73-9b53-328f2a152e76]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-acylcarnitine-dbs: ValueSet.compose.include[0].concept[70]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 33284
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '53191-3' is not valid in the system http://loinc.org (error: [2e1d18e8-f2d4-4f05-be2a-f65c990c3758]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-acylcarnitine-dbs: ValueSet.compose.include[0].concept[71]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 33388
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '53193-9' is not valid in the system http://loinc.org (error: [3b90508e-bd34-4461-a686-667cd8cac743]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-acylcarnitine-dbs: ValueSet.compose.include[0].concept[72]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 33499
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '53194-7' is not valid in the system http://loinc.org (error: [4058ceaa-9c0d-4b77-96df-d81c1ecd8095]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-acylcarnitine-dbs: ValueSet.compose.include[0].concept[73]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 33602
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '88025-2' is not valid in the system http://loinc.org (error: [3aba1c60-c439-4c25-88c1-023c69f824d3]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-acylcarnitine-dbs: ValueSet.compose.include[0].concept[74]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 33710
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '53195-4' is not valid in the system http://loinc.org (error: [67dfc4b4-17c2-4cb0-96f6-0eb99407f952]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-acylcarnitine-dbs: ValueSet.compose.include[0].concept[75]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 33822
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '70159-9' is not valid in the system http://loinc.org (error: [83bfdb1d-2816-4597-b691-9d529c64eb12]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-acylcarnitine-dbs: ValueSet.compose.include[0].concept[76]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 33898
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '53170-7' is not valid in the system http://loinc.org (error: [05039e27-f33d-4a40-86eb-45cd95a5fcdc]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-acylcarnitine-dbs: ValueSet.compose.include[0].concept[77]"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/OperationOutcome/ValueSet-mii-vs-seltene-nbs-aminoacid-dbs",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ValueSet-mii-vs-seltene-nbs-aminoacid-dbs",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 28154
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablevalueset|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-aminoacid-dbs: ValueSet.jurisdiction[0].coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 28361
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '47559-0' is not valid in the system http://loinc.org (error: [049c97e2-28d1-4eb1-8867-e3ed994fda3e]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-aminoacid-dbs: ValueSet.compose.include[0].concept[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 28436
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '53064-2' is not valid in the system http://loinc.org (error: [b926db64-6e12-4133-8368-a537a8d0551a]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-aminoacid-dbs: ValueSet.compose.include[0].concept[2]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 28507
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '47539-2' is not valid in the system http://loinc.org (error: [a319ad5f-17f8-4445-9a55-82e639d8ab1f]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-aminoacid-dbs: ValueSet.compose.include[0].concept[3]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 28568
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '47551-7' is not valid in the system http://loinc.org (error: [2d89a8b1-6972-44fc-9408-c570e93b3006]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-aminoacid-dbs: ValueSet.compose.include[0].concept[4]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 28632
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '47556-6' is not valid in the system http://loinc.org (error: [135799dd-0b60-4f98-8d48-5a81a99ea818]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-aminoacid-dbs: ValueSet.compose.include[0].concept[5]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 28698
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '88018-7' is not valid in the system http://loinc.org (error: [53421a05-8d74-4d3c-b3b9-7c9e079789dc]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-aminoacid-dbs: ValueSet.compose.include[0].concept[6]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 28766
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '94572-5' is not valid in the system http://loinc.org (error: [e8be8566-b07b-49f5-9246-410868cd2349]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-aminoacid-dbs: ValueSet.compose.include[0].concept[7]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 28858
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '74875-6' is not valid in the system http://loinc.org (error: [87a578d5-c5a4-4f8b-82b8-7e8b327865e7]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-aminoacid-dbs: ValueSet.compose.include[0].concept[8]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 28930
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '50083-5' is not valid in the system http://loinc.org (error: [77de7e48-340b-4073-8736-52ca012d55ed]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-aminoacid-dbs: ValueSet.compose.include[0].concept[9]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 28992
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '47562-4' is not valid in the system http://loinc.org (error: [4620cd88-4cc8-425a-a550-8136d769b7d3]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-aminoacid-dbs: ValueSet.compose.include[0].concept[10]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 29078
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '74876-4' is not valid in the system http://loinc.org (error: [551cb0e4-19a8-4cb0-a1fd-ea41882fc9f7]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-aminoacid-dbs: ValueSet.compose.include[0].concept[11]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 29136
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '43927-3' is not valid in the system http://loinc.org (error: [0c65fe32-39da-4d59-b7f4-c960e12ba552]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-aminoacid-dbs: ValueSet.compose.include[0].concept[12]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 29201
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '47567-3' is not valid in the system http://loinc.org (error: [a057b58b-78d6-4866-8741-0616deb7c12a]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-aminoacid-dbs: ValueSet.compose.include[0].concept[13]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 29272
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '75214-7' is not valid in the system http://loinc.org (error: [bf2e3c79-a969-4eb5-9e86-2615f625b789]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-aminoacid-dbs: ValueSet.compose.include[0].concept[14]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 29347
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '53398-4' is not valid in the system http://loinc.org (error: [a7097317-9d11-48f9-bf74-8664f8b53ac3]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-aminoacid-dbs: ValueSet.compose.include[0].concept[15]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 29442
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '74877-2' is not valid in the system http://loinc.org (error: [b4aa2fce-7f3a-4722-af05-20cb20a37c0b]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-aminoacid-dbs: ValueSet.compose.include[0].concept[16]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 29513
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '53062-6' is not valid in the system http://loinc.org (error: [ea994f05-af49-4de1-bcc5-fd278a7591f4]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-aminoacid-dbs: ValueSet.compose.include[0].concept[17]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 29592
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '53200-2' is not valid in the system http://loinc.org (error: [7aa7fc85-3389-4a5d-beb1-54a9901ce6d6]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-aminoacid-dbs: ValueSet.compose.include[0].concept[18]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 29656
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '47572-3' is not valid in the system http://loinc.org (error: [b5723ee8-08d0-4005-af05-f55fad4da857]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-aminoacid-dbs: ValueSet.compose.include[0].concept[19]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 29722
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '53063-4' is not valid in the system http://loinc.org (error: [54a39938-1566-4bec-a24a-2f4c1e3d6f91]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-aminoacid-dbs: ValueSet.compose.include[0].concept[20]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 29785
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '38480-0' is not valid in the system http://loinc.org (error: [bec1682c-2b5f-488a-9e6a-13962b16237b]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-aminoacid-dbs: ValueSet.compose.include[0].concept[21]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 29849
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '42892-0' is not valid in the system http://loinc.org (error: [0a534bfd-a364-4bc2-90b6-cd41c253bcb6]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-aminoacid-dbs: ValueSet.compose.include[0].concept[22]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 29921
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '54092-2' is not valid in the system http://loinc.org (error: [1ebf4411-f88d-45d7-af31-399aae9613f2]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-aminoacid-dbs: ValueSet.compose.include[0].concept[23]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 29998
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '53157-4' is not valid in the system http://loinc.org (error: [92272718-d757-488e-836a-007db7174a49]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-aminoacid-dbs: ValueSet.compose.include[0].concept[24]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 30070
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '53399-2' is not valid in the system http://loinc.org (error: [4cf4f1c5-1a14-4951-80d7-80e2a0e6e7ed]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-aminoacid-dbs: ValueSet.compose.include[0].concept[25]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 30137
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '53066-7' is not valid in the system http://loinc.org (error: [b6255d09-d28b-49a9-9868-74e216c406ed]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-aminoacid-dbs: ValueSet.compose.include[0].concept[26]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 30210
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '38481-8' is not valid in the system http://loinc.org (error: [4ed72979-1396-4830-826e-053acbf461e0]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-aminoacid-dbs: ValueSet.compose.include[0].concept[27]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 30307
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '74878-0' is not valid in the system http://loinc.org (error: [52919fea-b9d9-4e23-a0d2-3d4430c39808]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-aminoacid-dbs: ValueSet.compose.include[0].concept[28]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 30381
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '53095-6' is not valid in the system http://loinc.org (error: [13649f12-97bd-4eee-8f58-503b41ef766c]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-aminoacid-dbs: ValueSet.compose.include[0].concept[29]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 30478
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '53233-3' is not valid in the system http://loinc.org (error: [33750029-c93f-459a-85fe-bf07934bba37]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-aminoacid-dbs: ValueSet.compose.include[0].concept[30]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 30574
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '53234-1' is not valid in the system http://loinc.org (error: [727aa295-91cb-47c5-b095-d6faa76e903d]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-aminoacid-dbs: ValueSet.compose.include[0].concept[31]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 30637
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '47630-9' is not valid in the system http://loinc.org (error: [41ac2d92-f92c-4ad0-86f2-307c6bd7ef70]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-aminoacid-dbs: ValueSet.compose.include[0].concept[32]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 30698
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '47633-3' is not valid in the system http://loinc.org (error: [416bf1af-c0c3-4e6f-a0a5-4b88b6063530]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-aminoacid-dbs: ValueSet.compose.include[0].concept[33]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 30762
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '47638-2' is not valid in the system http://loinc.org (error: [427ba93e-008d-435f-8885-885e92fc9c71]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-aminoacid-dbs: ValueSet.compose.include[0].concept[34]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 30832
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '93488-5' is not valid in the system http://loinc.org (error: [63b372ef-d117-4f52-b603-5f6c759908f3]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-aminoacid-dbs: ValueSet.compose.include[0].concept[35]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 30911
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '107506-8' is not valid in the system http://loinc.org (error: [a8fc9eb0-4ed1-476d-9976-56dde4b3e236]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-aminoacid-dbs: ValueSet.compose.include[0].concept[36]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 30992
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '104195-3' is not valid in the system http://loinc.org (error: [c9a8d5ee-5f12-44b9-96ea-ab6f4190eab4]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-aminoacid-dbs: ValueSet.compose.include[0].concept[37]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 31055
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '47643-2' is not valid in the system http://loinc.org (error: [980f9831-3c33-4e12-8ba0-d21f988dbc6d]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-aminoacid-dbs: ValueSet.compose.include[0].concept[38]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 31121
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '47648-1' is not valid in the system http://loinc.org (error: [91dc7eb3-7d64-49f7-aceb-d3b5909fc432]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-aminoacid-dbs: ValueSet.compose.include[0].concept[39]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 31189
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '53158-2' is not valid in the system http://loinc.org (error: [be51a4bc-34b2-416a-a643-a350e638b9c4]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-aminoacid-dbs: ValueSet.compose.include[0].concept[40]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 31251
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '44376-2' is not valid in the system http://loinc.org (error: [9829330f-1314-4e46-9ee5-e953a0d37b8d]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-aminoacid-dbs: ValueSet.compose.include[0].concept[41]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 31317
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '54301-7' is not valid in the system http://loinc.org (error: [7b09c1cf-7f77-46cd-9862-033cdc13e626]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-aminoacid-dbs: ValueSet.compose.include[0].concept[42]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 31378
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '38486-7' is not valid in the system http://loinc.org (error: [08302081-242c-4767-887a-5b0bf98c3017]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-aminoacid-dbs: ValueSet.compose.include[0].concept[43]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 31443
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '54302-5' is not valid in the system http://loinc.org (error: [c72cd969-32a9-4db5-8e9c-22d5cf1dc933]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-aminoacid-dbs: ValueSet.compose.include[0].concept[44]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 31510
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '54303-3' is not valid in the system http://loinc.org (error: [0b7a48ab-0db8-4627-be41-db6e19f63ed2]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-aminoacid-dbs: ValueSet.compose.include[0].concept[45]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 31602
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '74880-6' is not valid in the system http://loinc.org (error: [f0de3ea9-09a9-43ca-9841-a5ab6bca6cd5]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-aminoacid-dbs: ValueSet.compose.include[0].concept[46]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 31670
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '47651-5' is not valid in the system http://loinc.org (error: [9e77a1d5-1877-4a52-ba58-031953f72829]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-aminoacid-dbs: ValueSet.compose.include[0].concept[47]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 31758
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '74881-4' is not valid in the system http://loinc.org (error: [47067077-fa2b-4a42-994f-8c148a4b72f7]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-aminoacid-dbs: ValueSet.compose.include[0].concept[48]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 31822
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '47671-3' is not valid in the system http://loinc.org (error: [9de93886-96da-454c-ab8c-29569cc21ccb]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-aminoacid-dbs: ValueSet.compose.include[0].concept[49]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 31889
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '47676-2' is not valid in the system http://loinc.org (error: [dd859c0d-d275-4520-9372-f3f7de706e01]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-aminoacid-dbs: ValueSet.compose.include[0].concept[50]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 31950
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '47679-6' is not valid in the system http://loinc.org (error: [6150eac6-d41a-4a36-9736-d8a18d069c82]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-aminoacid-dbs: ValueSet.compose.include[0].concept[51]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 32035
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '74882-2' is not valid in the system http://loinc.org (error: [70ffd275-8ce6-42d1-83d0-0791624959fd]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-aminoacid-dbs: ValueSet.compose.include[0].concept[52]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 32102
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '57994-6' is not valid in the system http://loinc.org (error: [b9f4b8f6-c118-4560-828b-9a245bada86f]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-aminoacid-dbs: ValueSet.compose.include[0].concept[53]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 32166
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '47684-6' is not valid in the system http://loinc.org (error: [8c98325a-e0cf-4b3e-9dd7-6d0f7f02ce9d]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-aminoacid-dbs: ValueSet.compose.include[0].concept[54]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 32240
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '75268-3' is not valid in the system http://loinc.org (error: [b839979f-8360-4dad-9f53-2ce84652228d]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-aminoacid-dbs: ValueSet.compose.include[0].concept[55]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 32313
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '57995-3' is not valid in the system http://loinc.org (error: [6d7f3871-60c4-41c3-bb3c-201555bdb7ef]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-aminoacid-dbs: ValueSet.compose.include[0].concept[56]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 32373
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '47689-5' is not valid in the system http://loinc.org (error: [7a4eae5f-1c30-4769-adf7-7c1946fd76b6]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-aminoacid-dbs: ValueSet.compose.include[0].concept[57]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 32436
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '47694-5' is not valid in the system http://loinc.org (error: [6a7e3568-2caa-42d4-bf41-3d39cf72183e]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-aminoacid-dbs: ValueSet.compose.include[0].concept[58]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 32523
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '74883-0' is not valid in the system http://loinc.org (error: [008f9a45-acdd-4f22-863b-e31d839e5d98]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-aminoacid-dbs: ValueSet.compose.include[0].concept[59]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 32586
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '47714-1' is not valid in the system http://loinc.org (error: [e8df8d28-8844-4729-9ce7-ea241d13ed02]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-aminoacid-dbs: ValueSet.compose.include[0].concept[60]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 32659
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '75215-4' is not valid in the system http://loinc.org (error: [6cc7bca8-b6fc-4065-9daa-f8c8f9414a5b]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-aminoacid-dbs: ValueSet.compose.include[0].concept[61]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 32726
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '109502-5' is not valid in the system http://loinc.org (error: [5cb1df78-148c-4e7f-9c92-a6c53a67b958]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-aminoacid-dbs: ValueSet.compose.include[0].concept[62]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 32792
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '29572-5' is not valid in the system http://loinc.org (error: [94056ede-0f41-48c6-ab7e-84f4d11a24bf]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-aminoacid-dbs: ValueSet.compose.include[0].concept[63]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 32883
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '74303-9' is not valid in the system http://loinc.org (error: [e8f61e1c-0fb2-4fed-9375-7171c091e49d]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-aminoacid-dbs: ValueSet.compose.include[0].concept[64]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 32950
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '29573-3' is not valid in the system http://loinc.org (error: [95221f7b-c713-46a4-8786-09bb324c025f]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-aminoacid-dbs: ValueSet.compose.include[0].concept[65]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 33013
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '29571-7' is not valid in the system http://loinc.org (error: [f5e92109-bb2b-4464-a4cc-9fd7a4552d01]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-aminoacid-dbs: ValueSet.compose.include[0].concept[66]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 33083
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '55969-0' is not valid in the system http://loinc.org (error: [4fa75f8e-a231-4fb5-9442-71f7c1d202ab]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-aminoacid-dbs: ValueSet.compose.include[0].concept[67]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 33182
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '74300-5' is not valid in the system http://loinc.org (error: [7e9312b9-b187-48a6-a205-4b8fc3245859]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-aminoacid-dbs: ValueSet.compose.include[0].concept[68]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 33257
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '35572-7' is not valid in the system http://loinc.org (error: [8b03f9f6-a618-4a82-9fa2-1c50eb3d0430]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-aminoacid-dbs: ValueSet.compose.include[0].concept[69]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 33324
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '54489-0' is not valid in the system http://loinc.org (error: [54143955-fd31-498c-a4cf-9ad2f28f0f6f]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-aminoacid-dbs: ValueSet.compose.include[0].concept[70]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 33388
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '54328-0' is not valid in the system http://loinc.org (error: [cbae79de-d660-41ef-ad11-9a949b474f52]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-aminoacid-dbs: ValueSet.compose.include[0].concept[71]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 33449
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '47732-3' is not valid in the system http://loinc.org (error: [ccdc1368-afe0-43b0-80b2-c7399916dba4]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-aminoacid-dbs: ValueSet.compose.include[0].concept[72]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 33513
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '47736-4' is not valid in the system http://loinc.org (error: [90edfc05-dbd4-44ec-a31b-d9a6d55636ff]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-aminoacid-dbs: ValueSet.compose.include[0].concept[73]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 33587
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '53392-7' is not valid in the system http://loinc.org (error: [f634e8e1-98cc-46ca-a174-1313666473d2]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-aminoacid-dbs: ValueSet.compose.include[0].concept[74]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 33651
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '47700-0' is not valid in the system http://loinc.org (error: [5f2a2512-62d5-43c1-8da5-80aa0dbb9742]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-aminoacid-dbs: ValueSet.compose.include[0].concept[75]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 33711
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '63380-0' is not valid in the system http://loinc.org (error: [adebfbd0-1839-4880-848c-eeaa430db285]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-aminoacid-dbs: ValueSet.compose.include[0].concept[76]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 33778
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '47705-9' is not valid in the system http://loinc.org (error: [1125bf60-c27e-4f8d-a20b-96621150e975]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-aminoacid-dbs: ValueSet.compose.include[0].concept[77]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 33855
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '53156-6' is not valid in the system http://loinc.org (error: [1e254122-1315-4158-9492-0af43ce4839b]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-aminoacid-dbs: ValueSet.compose.include[0].concept[78]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 33915
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '47742-2' is not valid in the system http://loinc.org (error: [fda0b204-57b0-4ca3-9615-3b7d199cdd52]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-aminoacid-dbs: ValueSet.compose.include[0].concept[79]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 33978
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '47747-1' is not valid in the system http://loinc.org (error: [c829fd69-0ecb-4967-be4b-83dde1407318]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-aminoacid-dbs: ValueSet.compose.include[0].concept[80]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 34039
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '47782-8' is not valid in the system http://loinc.org (error: [a5069a39-8909-40e7-939a-7f457d208e4f]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-aminoacid-dbs: ValueSet.compose.include[0].concept[81]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 34102
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '47784-4' is not valid in the system http://loinc.org (error: [34001c1e-3236-4d9c-9ecb-56af5bb7d439]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-aminoacid-dbs: ValueSet.compose.include[0].concept[82]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 34168
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '47789-3' is not valid in the system http://loinc.org (error: [a80b0fe0-754e-48bd-86fe-e4ede7ca1db8]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-aminoacid-dbs: ValueSet.compose.include[0].concept[83]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 34237
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '79330-7' is not valid in the system http://loinc.org (error: [38cb4278-875e-4410-bfc4-a00a51571c7a]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-aminoacid-dbs: ValueSet.compose.include[0].concept[84]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 34301
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '53159-0' is not valid in the system http://loinc.org (error: [8e6922bf-ce52-4533-9f20-bc83e0466b48]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-aminoacid-dbs: ValueSet.compose.include[0].concept[85]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 34363
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '35571-9' is not valid in the system http://loinc.org (error: [a531c267-89a0-45ee-9101-bede0225b0ae]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-aminoacid-dbs: ValueSet.compose.include[0].concept[86]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 34424
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '45032-0' is not valid in the system http://loinc.org (error: [6cb50c99-63f2-4748-862d-1f9b82669dce]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-aminoacid-dbs: ValueSet.compose.include[0].concept[87]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 34510
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '74302-1' is not valid in the system http://loinc.org (error: [e281d3f2-26f4-4a4b-8600-921caf2714c0]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-aminoacid-dbs: ValueSet.compose.include[0].concept[88]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 34575
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '47796-8' is not valid in the system http://loinc.org (error: [a000dce3-2870-49b6-9fbd-be7abf13a514]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-aminoacid-dbs: ValueSet.compose.include[0].concept[89]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 34650
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '74481-3' is not valid in the system http://loinc.org (error: [d1a598cc-8a8b-49f6-b619-0b40ca334e3b]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-aminoacid-dbs: ValueSet.compose.include[0].concept[90]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 34749
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '74299-9' is not valid in the system http://loinc.org (error: [f081cf28-39f8-4507-9e4f-611ca2249d45]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-aminoacid-dbs: ValueSet.compose.include[0].concept[91]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 34833
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '74884-8' is not valid in the system http://loinc.org (error: [e523c5fb-48da-462b-9d90-dd4be58c1172]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-aminoacid-dbs: ValueSet.compose.include[0].concept[92]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 34893
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '47799-2' is not valid in the system http://loinc.org (error: [d0159026-98da-4a9e-b2b1-cc34ff465b27]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-aminoacid-dbs: ValueSet.compose.include[0].concept[93]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 34956
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '47804-0' is not valid in the system http://loinc.org (error: [c7641222-b2d3-4baa-a5c7-a1dacab78a77]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-aminoacid-dbs: ValueSet.compose.include[0].concept[94]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 35029
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '53151-7' is not valid in the system http://loinc.org (error: [64fc0db6-37a7-4636-a431-1358e71eeaaa]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-aminoacid-dbs: ValueSet.compose.include[0].concept[95]"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/OperationOutcome/ValueSet-mii-vs-seltene-nbs-dbs-all",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ValueSet-mii-vs-seltene-nbs-dbs-all",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 5696
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablevalueset|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-dbs-all: ValueSet.jurisdiction[0].coding[0].system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/OperationOutcome/ValueSet-mii-vs-seltene-nbs-enzyme-activity-dbs",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ValueSet-mii-vs-seltene-nbs-enzyme-activity-dbs",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 15107
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablevalueset|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-enzyme-activity-dbs: ValueSet.jurisdiction[0].coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 15354
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '79455-2' is not valid in the system http://loinc.org (error: [32374bc5-d6f0-4681-8b01-8a8b05a226e7]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-enzyme-activity-dbs: ValueSet.compose.include[0].concept[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 15454
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '88019-5' is not valid in the system http://loinc.org (error: [3eb41183-0b17-4a7a-896e-3c7e9dc77544]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-enzyme-activity-dbs: ValueSet.compose.include[0].concept[2]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 15554
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '79463-6' is not valid in the system http://loinc.org (error: [61c1064c-7f51-4171-aaa3-ec4859408d1a]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-enzyme-activity-dbs: ValueSet.compose.include[0].concept[3]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 15685
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '75094-3' is not valid in the system http://loinc.org (error: [d5316275-e6ea-4772-987b-5a41c2cf75d4]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-enzyme-activity-dbs: ValueSet.compose.include[0].concept[4]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 15792
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '42906-8' is not valid in the system http://loinc.org (error: [fe66013f-8f08-400c-af10-d84f134b7542]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-enzyme-activity-dbs: ValueSet.compose.include[0].concept[5]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 15881
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '55827-0' is not valid in the system http://loinc.org (error: [3bd71ca2-f630-4134-ba32-178ccf864df6]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-enzyme-activity-dbs: ValueSet.compose.include[0].concept[6]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 15969
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '62316-5' is not valid in the system http://loinc.org (error: [50879fa0-f402-45fd-8b49-d52c31cdf162]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-enzyme-activity-dbs: ValueSet.compose.include[0].concept[7]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 16055
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '75052-1' is not valid in the system http://loinc.org (error: [f3f916c8-4b9c-4637-8ac6-47c444957bec]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-enzyme-activity-dbs: ValueSet.compose.include[0].concept[8]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 16146
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '96586-3' is not valid in the system http://loinc.org (error: [4b710211-05e8-4222-b750-72109d4ea942]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-enzyme-activity-dbs: ValueSet.compose.include[0].concept[9]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 16229
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '79454-5' is not valid in the system http://loinc.org (error: [5f64e993-8ed1-4029-9b4c-8d2a3334da74]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-enzyme-activity-dbs: ValueSet.compose.include[0].concept[10]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 16326
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '104114-4' is not valid in the system http://loinc.org (error: [699ba1d1-3cda-4945-a605-d234ce379b25]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-enzyme-activity-dbs: ValueSet.compose.include[0].concept[11]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 16414
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '55908-8' is not valid in the system http://loinc.org (error: [b56dbf98-8c41-4866-9435-6a03d749e967]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-enzyme-activity-dbs: ValueSet.compose.include[0].concept[12]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 16498
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '55910-4' is not valid in the system http://loinc.org (error: [2fc347e1-2ec4-44cd-af4c-6aab4840d50c]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-enzyme-activity-dbs: ValueSet.compose.include[0].concept[13]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 16578
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '55912-0' is not valid in the system http://loinc.org (error: [8fee4de1-9a3b-49f6-b95b-2504179d740a]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-enzyme-activity-dbs: ValueSet.compose.include[0].concept[14]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 16671
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '96587-1' is not valid in the system http://loinc.org (error: [dc78ad16-1ee3-4a6a-a85f-6ef71eecc7a2]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-enzyme-activity-dbs: ValueSet.compose.include[0].concept[15]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 16765
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '79458-6' is not valid in the system http://loinc.org (error: [9b70465a-ecc4-4eff-98ab-bd546bd2946b]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-enzyme-activity-dbs: ValueSet.compose.include[0].concept[16]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 16850
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '55916-1' is not valid in the system http://loinc.org (error: [a857b695-12fe-43d3-8217-1f4510d434a3]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-enzyme-activity-dbs: ValueSet.compose.include[0].concept[17]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 16935
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '79457-8' is not valid in the system http://loinc.org (error: [e436ade9-9c61-4332-8e9d-3734c3da58cb]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-enzyme-activity-dbs: ValueSet.compose.include[0].concept[18]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 17031
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '80425-2' is not valid in the system http://loinc.org (error: [61746583-bbdd-4ef6-93b5-b3adf8b7e3ed]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-enzyme-activity-dbs: ValueSet.compose.include[0].concept[19]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 17109
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '75217-0' is not valid in the system http://loinc.org (error: [d22d7b70-a5b8-4ac8-9fa5-6ae3e15c1fa9]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-enzyme-activity-dbs: ValueSet.compose.include[0].concept[20]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 17198
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '111824-9' is not valid in the system http://loinc.org (error: [9bd4497b-3931-4564-bf0a-537476ba98b2]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-enzyme-activity-dbs: ValueSet.compose.include[0].concept[21]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 17280
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '55836-1' is not valid in the system http://loinc.org (error: [9225d290-d8d2-456f-b376-72a2d8ac36d7]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-enzyme-activity-dbs: ValueSet.compose.include[0].concept[22]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 17367
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '73958-1' is not valid in the system http://loinc.org (error: [7294f3a3-36a5-47c7-89de-0b0c726c5feb]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-enzyme-activity-dbs: ValueSet.compose.include[0].concept[23]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 17453
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '107446-7' is not valid in the system http://loinc.org (error: [8c328977-f4a2-4a73-85e9-f2549bbb9232]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-enzyme-activity-dbs: ValueSet.compose.include[0].concept[24]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 17540
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '62310-8' is not valid in the system http://loinc.org (error: [af8c1787-7a4c-487b-9e0e-ec93c26c71e8]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-enzyme-activity-dbs: ValueSet.compose.include[0].concept[25]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 17633
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '96593-9' is not valid in the system http://loinc.org (error: [71a293fe-aa5a-4379-a038-d6b9639bee83]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-enzyme-activity-dbs: ValueSet.compose.include[0].concept[26]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 17718
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '55917-9' is not valid in the system http://loinc.org (error: [b178691c-8489-4b63-b462-6b472c96ec59]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-enzyme-activity-dbs: ValueSet.compose.include[0].concept[27]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 17805
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '104113-6' is not valid in the system http://loinc.org (error: [6e358ad2-9023-4589-8dc8-7e36bcb63c2a]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-enzyme-activity-dbs: ValueSet.compose.include[0].concept[28]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 17893
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '79462-8' is not valid in the system http://loinc.org (error: [28b7df39-d161-4b87-9729-4ee36b4cca5a]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-enzyme-activity-dbs: ValueSet.compose.include[0].concept[29]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 17990
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '59246-9' is not valid in the system http://loinc.org (error: [93a8f092-e62e-4862-95a6-5beaf8487c1d]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-enzyme-activity-dbs: ValueSet.compose.include[0].concept[30]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 18088
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '79467-7' is not valid in the system http://loinc.org (error: [972c3ef1-956e-4277-8829-af437e70cbec]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-enzyme-activity-dbs: ValueSet.compose.include[0].concept[31]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 18178
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '75058-8' is not valid in the system http://loinc.org (error: [c5d6717e-882b-4eac-b7a9-72bd947058f6]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-enzyme-activity-dbs: ValueSet.compose.include[0].concept[32]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 18268
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '72498-9' is not valid in the system http://loinc.org (error: [4735d1d4-d954-42e6-b3c3-c3ef340c41d9]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-enzyme-activity-dbs: ValueSet.compose.include[0].concept[33]"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/OperationOutcome/ValueSet-mii-vs-seltene-nbs-hemoglobin-dbs",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ValueSet-mii-vs-seltene-nbs-hemoglobin-dbs",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 7974
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablevalueset|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-hemoglobin-dbs: ValueSet.jurisdiction[0].coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8179
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '96595-4' is not valid in the system http://loinc.org (error: [87deefb8-26d6-4393-af2b-069e1b331913]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-hemoglobin-dbs: ValueSet.compose.include[0].concept[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8247
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '54072-4' is not valid in the system http://loinc.org (error: [655897c7-8a4f-45fb-a0c2-f4da2f22cd02]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-hemoglobin-dbs: ValueSet.compose.include[0].concept[2]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8315
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '54073-2' is not valid in the system http://loinc.org (error: [3c7d7d89-8dc0-46fd-83b4-95623121c3b1]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-hemoglobin-dbs: ValueSet.compose.include[0].concept[3]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8383
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '54070-8' is not valid in the system http://loinc.org (error: [fdf30266-89f9-4592-b512-7d3e6c7e5098]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-hemoglobin-dbs: ValueSet.compose.include[0].concept[4]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8451
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '54071-6' is not valid in the system http://loinc.org (error: [bd827ce5-4912-42d8-a8fc-de72393d0bbe]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-hemoglobin-dbs: ValueSet.compose.include[0].concept[5]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8519
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '54074-0' is not valid in the system http://loinc.org (error: [815945cb-4291-4e8e-b9e8-bd6a25c7545f]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-hemoglobin-dbs: ValueSet.compose.include[0].concept[6]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8594
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '54068-2' is not valid in the system http://loinc.org (error: [38576d1d-b5e4-4e05-9212-3e715dd4655c]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-hemoglobin-dbs: ValueSet.compose.include[0].concept[7]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8662
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '56476-5' is not valid in the system http://loinc.org (error: [82b05009-9f7c-4375-8955-a0fb690cf4d6]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-hemoglobin-dbs: ValueSet.compose.include[0].concept[8]"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/OperationOutcome/ValueSet-mii-vs-seltene-nbs-ratio-dbs",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ValueSet-mii-vs-seltene-nbs-ratio-dbs",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 18626
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablevalueset|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-ratio-dbs: ValueSet.jurisdiction[0].coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 18910
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '53172-3' is not valid in the system http://loinc.org (error: [ce0914f4-764a-4e34-89e2-a119ead95726]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-ratio-dbs: ValueSet.compose.include[0].concept[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 19024
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '53201-0' is not valid in the system http://loinc.org (error: [8292d70b-b28d-4a0d-8f52-da6fd95bfdd3]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-ratio-dbs: ValueSet.compose.include[0].concept[2]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 19095
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '75214-7' is not valid in the system http://loinc.org (error: [5a3e843d-e118-49d7-979b-9456d4f55af8]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-ratio-dbs: ValueSet.compose.include[0].concept[3]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 19170
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '53398-4' is not valid in the system http://loinc.org (error: [013f27c9-170a-44ba-b0ab-b80bcdae3157]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-ratio-dbs: ValueSet.compose.include[0].concept[4]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 19249
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '53200-2' is not valid in the system http://loinc.org (error: [10599a26-06ad-4fa5-a015-1ff64195d6a7]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-ratio-dbs: ValueSet.compose.include[0].concept[5]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 19338
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '45192-2' is not valid in the system http://loinc.org (error: [954857d7-9b93-470a-a23e-d771b7073804]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-ratio-dbs: ValueSet.compose.include[0].concept[6]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 19410
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '54092-2' is not valid in the system http://loinc.org (error: [a9525bf4-301b-483b-ada4-6d579af20d74]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-ratio-dbs: ValueSet.compose.include[0].concept[7]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 19487
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '53157-4' is not valid in the system http://loinc.org (error: [49755e2c-92bd-46ff-a257-366d983e4d31]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-ratio-dbs: ValueSet.compose.include[0].concept[8]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 19559
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '53399-2' is not valid in the system http://loinc.org (error: [512084c7-a2f1-4c2b-9505-f8f2c2d17f49]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-ratio-dbs: ValueSet.compose.include[0].concept[9]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 19632
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '104196-1' is not valid in the system http://loinc.org (error: [4b9b0d33-e0f5-4402-be08-06dc60c75c96]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-ratio-dbs: ValueSet.compose.include[0].concept[10]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 19729
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '53233-3' is not valid in the system http://loinc.org (error: [c65fe365-7096-48d8-81ff-ab22e92efe7d]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-ratio-dbs: ValueSet.compose.include[0].concept[11]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 19825
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '53234-1' is not valid in the system http://loinc.org (error: [06ce9044-489f-48a6-b441-4f0bb611c7f8]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-ratio-dbs: ValueSet.compose.include[0].concept[12]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 19924
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '88016-1' is not valid in the system http://loinc.org (error: [0a7838eb-6f88-434d-bbd8-bdfe4212c0e6]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-ratio-dbs: ValueSet.compose.include[0].concept[13]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 20017
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '75225-3' is not valid in the system http://loinc.org (error: [52b5edb6-4be7-428d-b845-80d82e9dce99]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-ratio-dbs: ValueSet.compose.include[0].concept[14]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 20120
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '75216-2' is not valid in the system http://loinc.org (error: [d19b3602-6583-48f0-b7b9-708954eb5d75]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-ratio-dbs: ValueSet.compose.include[0].concept[15]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 20223
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '75267-5' is not valid in the system http://loinc.org (error: [48d7ce20-a863-49c4-9bef-54599c12a092]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-ratio-dbs: ValueSet.compose.include[0].concept[16]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 20325
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '88017-9' is not valid in the system http://loinc.org (error: [62a68051-1944-43ae-97f3-d702a66496ce]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-ratio-dbs: ValueSet.compose.include[0].concept[17]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 20404
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '107506-8' is not valid in the system http://loinc.org (error: [84c993bc-af44-45da-b6ea-5f2d87d01150]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-ratio-dbs: ValueSet.compose.include[0].concept[18]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 20485
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '104195-3' is not valid in the system http://loinc.org (error: [1343fad1-707f-431f-ac52-fd57e533275e]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-ratio-dbs: ValueSet.compose.include[0].concept[19]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 20559
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
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            "code": "business-rule",
            "details": {
              "text": "The code '75268-3' is not valid in the system http://loinc.org (error: [aee38348-5fe4-4ad9-a103-dda46650f4ac]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
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              "ValueSet/mii-vs-seltene-nbs-ratio-dbs: ValueSet.compose.include[0].concept[20]"
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          {
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 20660
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
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              {
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                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '75212-1' is not valid in the system http://loinc.org (error: [ec0ab515-8bae-4343-b270-f426c258eeba]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
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              "ValueSet/mii-vs-seltene-nbs-ratio-dbs: ValueSet.compose.include[0].concept[21]"
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 20780
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '53181-4' is not valid in the system http://loinc.org (error: [d561feb9-4d56-4c42-9a61-53efb672fde1]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-ratio-dbs: ValueSet.compose.include[0].concept[22]"
            ]
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          {
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 20864
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '80154-8' is not valid in the system http://loinc.org (error: [229aa41e-3b3b-467b-b9c6-6fb58a251c16]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-ratio-dbs: ValueSet.compose.include[0].concept[23]"
            ]
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          {
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 20960
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '53176-4' is not valid in the system http://loinc.org (error: [0259874b-7a7c-46d5-a4ee-82fd7526959b]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-ratio-dbs: ValueSet.compose.include[0].concept[24]"
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          {
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 21059
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
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              {
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                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
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            ],
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            "code": "business-rule",
            "details": {
              "text": "The code '53177-2' is not valid in the system http://loinc.org (error: [54f61d16-78f6-4971-bf4f-4922febb1562]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-ratio-dbs: ValueSet.compose.include[0].concept[25]"
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          {
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 21154
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '88014-6' is not valid in the system http://loinc.org (error: [a3551845-70a5-4b3d-b7f2-5d8b647ec625]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-ratio-dbs: ValueSet.compose.include[0].concept[26]"
            ]
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          {
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 21227
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '75215-4' is not valid in the system http://loinc.org (error: [2bc73f1a-c8ad-48ef-92b4-6a4352db99fd]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-ratio-dbs: ValueSet.compose.include[0].concept[27]"
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          {
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                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 21325
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '88015-3' is not valid in the system http://loinc.org (error: [5e32f630-d075-49d6-ac13-273270f53899]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-ratio-dbs: ValueSet.compose.include[0].concept[28]"
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          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 21422
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '88024-5' is not valid in the system http://loinc.org (error: [d06886c9-9001-4708-b43c-53409b856f8d]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-ratio-dbs: ValueSet.compose.include[0].concept[29]"
            ]
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          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 21521
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '74300-5' is not valid in the system http://loinc.org (error: [bcb1c7e8-41f5-4f46-a13f-5481114500d1]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-ratio-dbs: ValueSet.compose.include[0].concept[30]"
            ]
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          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 21596
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '35572-7' is not valid in the system http://loinc.org (error: [ee283da2-7284-40c5-a6fd-63794174f3d1]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-ratio-dbs: ValueSet.compose.include[0].concept[31]"
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          {
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 21670
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '53392-7' is not valid in the system http://loinc.org (error: [86b33fc6-1dcd-4a9f-bc7b-688d65cc1f92]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-ratio-dbs: ValueSet.compose.include[0].concept[32]"
            ]
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          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 21767
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '53163-2' is not valid in the system http://loinc.org (error: [930569d5-076b-44e3-94ac-80e981acb548]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-ratio-dbs: ValueSet.compose.include[0].concept[33]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 21863
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '53162-4' is not valid in the system http://loinc.org (error: [a8fbaaa8-ed0b-4a44-9bd8-d3d24961eac2]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-ratio-dbs: ValueSet.compose.include[0].concept[34]"
            ]
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          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 21964
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '53164-0' is not valid in the system http://loinc.org (error: [7f4dc623-cef3-4f6c-a216-c3cb64b551fe]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-ratio-dbs: ValueSet.compose.include[0].concept[35]"
            ]
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          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 22051
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '53161-6' is not valid in the system http://loinc.org (error: [b7ef6ba8-38a9-4d26-b789-a17e1cd9cddc]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-ratio-dbs: ValueSet.compose.include[0].concept[36]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 22128
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '53156-6' is not valid in the system http://loinc.org (error: [165f8c4c-11d5-4865-bb7d-d18644e2f154]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-ratio-dbs: ValueSet.compose.include[0].concept[37]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 22228
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '53400-8' is not valid in the system http://loinc.org (error: [342f0d01-74ad-4e37-a9d9-9e69ffcac6ba]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-ratio-dbs: ValueSet.compose.include[0].concept[38]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 22332
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '53193-9' is not valid in the system http://loinc.org (error: [8b7c440c-50f7-44e3-b0cc-38bbb37b889b]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-ratio-dbs: ValueSet.compose.include[0].concept[39]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 22443
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '53194-7' is not valid in the system http://loinc.org (error: [7d8197f6-4eb2-4237-8a12-fb18d85b986a]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-ratio-dbs: ValueSet.compose.include[0].concept[40]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 22546
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '88025-2' is not valid in the system http://loinc.org (error: [82e931b5-3b8b-4428-858a-589806ca7e4f]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-ratio-dbs: ValueSet.compose.include[0].concept[41]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 22654
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '53195-4' is not valid in the system http://loinc.org (error: [c86928b9-6398-41c3-b360-f937997710af]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-ratio-dbs: ValueSet.compose.include[0].concept[42]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 22766
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '70159-9' is not valid in the system http://loinc.org (error: [25d76d28-9e04-488d-81bb-ab7472c9a85d]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-ratio-dbs: ValueSet.compose.include[0].concept[43]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 22841
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '74481-3' is not valid in the system http://loinc.org (error: [ebf3c5bb-e30e-40fb-b28f-51ac0fec1f9b]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-ratio-dbs: ValueSet.compose.include[0].concept[44]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 22940
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '74299-9' is not valid in the system http://loinc.org (error: [8ea7cf44-b235-40f5-b1d7-5f2f28783e7f]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-ratio-dbs: ValueSet.compose.include[0].concept[45]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 23013
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '53151-7' is not valid in the system http://loinc.org (error: [862cc013-2a06-481f-bbc9-7bb9b54a9d30]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-ratio-dbs: ValueSet.compose.include[0].concept[46]"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/OperationOutcome/ValueSet-mii-vs-seltene-nbs-target-analyte",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ValueSet-mii-vs-seltene-nbs-target-analyte",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10966
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablevalueset|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-target-analyte: ValueSet.jurisdiction[0].coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 11169
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '38473-5' is not valid in the system http://loinc.org (error: [119d517a-b465-4e20-bdfc-d3308ecf880a]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-target-analyte: ValueSet.compose.include[0].concept[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 11247
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '75217-0' is not valid in the system http://loinc.org (error: [35abf590-71fb-41cd-8fb7-c6692b42613b]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-target-analyte: ValueSet.compose.include[0].concept[2]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 11309
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '54084-9' is not valid in the system http://loinc.org (error: [b1105f93-19ee-4627-984b-be70221279ea]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-target-analyte: ValueSet.compose.include[0].concept[3]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 11376
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '29573-3' is not valid in the system http://loinc.org (error: [d2e206bd-da7c-4879-b913-4ff04184e1e1]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-target-analyte: ValueSet.compose.include[0].concept[4]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 11437
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '47679-6' is not valid in the system http://loinc.org (error: [31a83e0e-4d96-4a01-a1a7-28dc111a6450]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-target-analyte: ValueSet.compose.include[0].concept[5]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 11513
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '53175-6' is not valid in the system http://loinc.org (error: [3ea5f46c-d048-4684-b895-d41ee1451c04]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-target-analyte: ValueSet.compose.include[0].concept[6]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 11603
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '50125-4' is not valid in the system http://loinc.org (error: [4a0e93ea-cfd6-48db-b6c5-ea11d2fd1034]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-target-analyte: ValueSet.compose.include[0].concept[7]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 11687
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '53191-3' is not valid in the system http://loinc.org (error: [858e6f20-bb03-4b96-a714-03b4ae98956f]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-target-analyte: ValueSet.compose.include[0].concept[8]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 11760
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '38481-8' is not valid in the system http://loinc.org (error: [0bb39d19-5a4c-486f-982a-7b733a051e29]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-target-analyte: ValueSet.compose.include[0].concept[9]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 11838
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '53199-6' is not valid in the system http://loinc.org (error: [e8dbce99-6cff-43c0-b4d6-072aa098cfd6]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-target-analyte: ValueSet.compose.include[0].concept[10]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 11959
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '53235-8' is not valid in the system http://loinc.org (error: [ea86aa20-d302-46da-a515-11b24c8ec4f4]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-target-analyte: ValueSet.compose.include[0].concept[11]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 12038
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '45207-8' is not valid in the system http://loinc.org (error: [1b9f8173-fd54-4d77-b487-d39bcd6646b9]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-target-analyte: ValueSet.compose.include[0].concept[12]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 12116
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '42920-9' is not valid in the system http://loinc.org (error: [aec71b82-1c4d-411f-9252-1f09a919ab35]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-target-analyte: ValueSet.compose.include[0].concept[13]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 12185
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '53231-7' is not valid in the system http://loinc.org (error: [957b69c3-14c8-4a95-b776-a5e12e485dbf]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-target-analyte: ValueSet.compose.include[0].concept[14]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 12294
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '62320-7' is not valid in the system http://loinc.org (error: [9a59b73b-e906-4574-89bc-6cd1d1c0d466]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-target-analyte: ValueSet.compose.include[0].concept[15]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 12368
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '54081-5' is not valid in the system http://loinc.org (error: [f8d0c426-3bab-4ea9-a760-43c3a93d3735]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-target-analyte: ValueSet.compose.include[0].concept[16]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 12464
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '92002-5' is not valid in the system http://loinc.org (error: [6e24be55-9359-45be-a380-c619fb7417c0]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-target-analyte: ValueSet.compose.include[0].concept[17]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 12541
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '53160-8' is not valid in the system http://loinc.org (error: [c2a4a099-181c-4aa1-8856-8e925c5b2347]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-target-analyte: ValueSet.compose.include[0].concept[18]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 12605
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '47700-0' is not valid in the system http://loinc.org (error: [4419febc-da79-43a9-9081-50aafd5d50e5]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-target-analyte: ValueSet.compose.include[0].concept[19]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 12676
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '48633-2' is not valid in the system http://loinc.org (error: [5f9226ee-a735-4cc1-8e7d-5c5089c7c83b]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-nbs-target-analyte: ValueSet.compose.include[0].concept[20]"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/OperationOutcome/ValueSet-mii-vs-seltene-penetrance",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ValueSet-mii-vs-seltene-penetrance",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 6625
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablevalueset|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-penetrance: ValueSet.jurisdiction[0].coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 6841
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'HP:0003829' is not valid in the system http://human-phenotype-ontology.org (error: [f6e54ff4-a51c-4e45-8c60-4b0693cc284c]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-penetrance: ValueSet.compose.include[0].concept[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 6903
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'HP:4000158' is not valid in the system http://human-phenotype-ontology.org (error: [74a16706-ab09-4e60-9823-4ea8d565be03]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-penetrance: ValueSet.compose.include[0].concept[2]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 6969
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'HP:4000159' is not valid in the system http://human-phenotype-ontology.org (error: [4d7814a0-9fc8-4ca0-8b1c-ac9a9f0622df]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-penetrance: ValueSet.compose.include[0].concept[3]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 7030
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'HP:4000160' is not valid in the system http://human-phenotype-ontology.org (error: [775430b1-9d8f-41ef-8cd2-3bff9039836f]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-penetrance: ValueSet.compose.include[0].concept[4]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 7102
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'HP:0003831' is not valid in the system http://human-phenotype-ontology.org (error: [efe28380-790d-4d3a-9f16-f2a279831649]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-penetrance: ValueSet.compose.include[0].concept[5]"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/OperationOutcome/ValueSet-mii-vs-seltene-symptom-change-status-combined",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ValueSet-mii-vs-seltene-symptom-change-status-combined",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10217
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablevalueset|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-symptom-change-status-combined: ValueSet.jurisdiction[0].coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10753
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '231877006' is not valid in the system http://snomed.info/sct (error: [9881eb52-ccd7-4462-866a-405b8e12d959]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-symptom-change-status-combined: ValueSet.compose.include[1].concept[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10797
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '385630006' is not valid in the system http://snomed.info/sct (error: [00247671-41fb-4119-939d-f870506e8c6e]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-symptom-change-status-combined: ValueSet.compose.include[1].concept[2]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10835
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '2667000' is not valid in the system http://snomed.info/sct (error: [9909e827-9166-485c-806b-bfdc05579749]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-symptom-change-status-combined: ValueSet.compose.include[1].concept[3]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10877
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '35105006' is not valid in the system http://snomed.info/sct (error: [a76047fe-ff50-407f-91cf-a6b7c77e5f98]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-symptom-change-status-combined: ValueSet.compose.include[1].concept[4]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10918
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '1250004' is not valid in the system http://snomed.info/sct (error: [42d5bb91-42ce-4c54-bcb1-d5c603ab406f]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-symptom-change-status-combined: ValueSet.compose.include[1].concept[5]"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/OperationOutcome/ValueSet-mii-vs-seltene-syndrome-category",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ValueSet-mii-vs-seltene-syndrome-category",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 6827
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablevalueset|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-syndrome-category: ValueSet.jurisdiction[0].coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 6997
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '75934005' is not valid in the system http://snomed.info/sct (error: [4bc74cf8-f8c4-41d0-9707-38543a785911]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-syndrome-category: ValueSet.compose.include[0].concept[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 7052
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '128139000' is not valid in the system http://snomed.info/sct (error: [886f31a3-0001-4882-b9d9-378421e30662]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-syndrome-category: ValueSet.compose.include[0].concept[2]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 7109
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '276654001' is not valid in the system http://snomed.info/sct (error: [fdb8786a-de93-4208-953f-3a38ebacc128]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-syndrome-category: ValueSet.compose.include[0].concept[3]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 7163
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '5294002' is not valid in the system http://snomed.info/sct (error: [70ffebbe-b96b-4491-ba83-b47d397ac095]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-syndrome-category: ValueSet.compose.include[0].concept[4]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 7218
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '362975008' is not valid in the system http://snomed.info/sct (error: [e05be26e-f192-43a8-ae7f-89db7f14e098]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-syndrome-category: ValueSet.compose.include[0].concept[5]"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/OperationOutcome/ValueSet-mii-vs-seltene-therapieempfehlung-strategie-medikamentoes",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ValueSet-mii-vs-seltene-therapieempfehlung-strategie-medikamentoes",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 9046
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablevalueset|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-therapieempfehlung-strategie-medikamentoes: ValueSet.jurisdiction[0].coding[0].system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/OperationOutcome/ValueSet-mii-vs-seltene-therapieempfehlung-strategie-nicht-medikamentoes",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ValueSet-mii-vs-seltene-therapieempfehlung-strategie-nicht-medikamentoes",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8397
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablevalueset|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-therapieempfehlung-strategie-nicht-medikamentoes: ValueSet.jurisdiction[0].coding[0].system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/OperationOutcome/ValueSet-mii-vs-seltene-therapieempfehlung-strategie",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ValueSet-mii-vs-seltene-therapieempfehlung-strategie",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 5821
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablevalueset|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-therapieempfehlung-strategie: ValueSet.jurisdiction[0].coding[0].system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/OperationOutcome/ValueSet-mii-vs-seltene-therapieempfehlung-typ",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ValueSet-mii-vs-seltene-therapieempfehlung-typ",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 5734
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablevalueset|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-therapieempfehlung-typ: ValueSet.jurisdiction[0].coding[0].system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/OperationOutcome/ValueSet-mii-vs-seltene-von-se-betroffen",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ValueSet-mii-vs-seltene-von-se-betroffen",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8091
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablevalueset|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-von-se-betroffen: ValueSet.jurisdiction[0].coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8233
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '373067005' is not valid in the system http://snomed.info/sct (error: [df53c27f-8f79-4356-854e-0b2bb11c0204]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-von-se-betroffen: ValueSet.compose.include[0].concept[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8274
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '261665006' is not valid in the system http://snomed.info/sct (error: [9518400f-539b-431c-9f13-b93cab0710b7]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-von-se-betroffen: ValueSet.compose.include[0].concept[2]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TYPE_SPECIFIC_CHECKS_DT_CANONICAL_MULTIPLE_POSSIBLE_VERSIONS"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "There are multiple different potential matches for the url 'http://terminology.hl7.org/CodeSystem/v2-0532'. It might be a good idea to fix to the correct version to reduce the likelihood of a wrong version being selected by an implementation/implementer, or use the [IG Parameter `pin-canonicals`](https://hl7.org/fhir/tools/CodeSystem-ig-parameters.html). Using version '3.0.0', found versions: 2.0.0 (from hl7.terminology.r4#6.1.0), 3.0.0 (from hl7.terminology.r4#7.1.0). Suggested fix: change the canonical reference from 'http://terminology.hl7.org/CodeSystem/v2-0532' to 'http://terminology.hl7.org/CodeSystem/v2-0532|3.0.0'"
            },
            "expression": [
              "ValueSet/mii-vs-seltene-von-se-betroffen: ValueSet.compose.include[1].system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-seltene/OperationOutcome/Parameters-mii-param-seltene-manifest",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Parameters-mii-param-seltene-manifest"
      }
    }
  ]
}