FHIR IG analytics| Package | de.medizininformatikinitiative.kerndatensatz.onkologie |
| Resource Type | StructureDefinition |
| Id | StructureDefinition-mii-lm-mvgenomseq-onkologie.json |
| FHIR Version | R4 |
| Source | https://medizininformatik-initiative.github.io/kerndatensatzmodul-onkologie/2027.0.0-ballot.1/StructureDefinition-mii-lm-mvgenomseq-onkologie.html |
| URL | https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-lm-mvgenomseq-onkologie |
| Version | 2027.0.0-ballot.1 |
| Status | active |
| Date | 2026-09-15T06:26:59+00:00 |
| Name | MII_LM_MVGenomSeq_Onkologie |
| Title | MII LM Modellvorhaben Genomsequenzierung Onkologie |
| Realm | de |
| Description | MII LogicalModel Modellvorhaben Genomsequenzierung Onkologie |
| Type | https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-lm-mvgenomseq-onkologie |
| Kind | logical |
No resources found
No resources found
Note: links and images are rebased to the (stated) source
English
Generated Narrative: StructureDefinition mii-lm-mvgenomseq-onkologie
| Name | Flags | Card. | Type | Description & Constraints |
|---|---|---|---|---|
  mii-lm-mvgenomseq-onkologie | 0..* | Element | MII LM Modellvorhaben Genomsequenzierung Onkologie Elements defined in Ancestors:@id, extension | |
  OnkologieFall | 0..* | BackboneElement | Onkologie-Fall | |
 Diagnose | 1..1 | BackboneElement | Diagnose | |
 Haupttumordiagnose | 1..1 | code | Haupttumordiagnose | |
| WeitereOnkologischeDiagnosen | 0..* | code | Weitere onkologische Diagnosen | |
| Hauptdiagnosedatum | 0..1 | date | Hauptdiagnosedatum | |
| ECOGStatus | 0..1 | code | ECOG-Status | |
| KeimbahndiagnoseVorhanden | 0..1 | code | Keimbahndiagnose vorhanden | |
| Keimbahndiagnose | 0..* | code | Keimbahndiagnose | |
| HPOPhaenotypisierung | 0..* | code | Phänotypisierung nach HPO | |
| Histologie | 1..1 | code | Histologie nach ICD-O-3 | |
| Topographie | 1..1 | code | Topographie nach ICD-O-3 | |
| Grading | 0..1 | code | Differenzierungsgrad | |
| TNMSchluessel | 0..1 | string | TNM-Klassifikation | |
| TNMSystematik | 0..1 | code | TNM-Systematik | |
| WeitereKlassifikationen | 0..* | string | Weitere Klassifikationen | |
 DiagnostischeVoruntersuchungen | 0..* | code | Diagnostische Voruntersuchungen | |
| Vordiagnostik | 0..* | BackboneElement | Vordiagnostik | |
| ArtDiagnostik | 1..1 | code | Diagnostik | |
| DatumDiagnostik | 0..1 | date | Datum | |
| MolekulareVorbefunde | 0..* | BackboneElement | klinisch relevante Ergebnisse der Diagnostik | |
| Gen | 1..1 | code | Gen | |
| Transkript | 0..1 | code | Transkript | |
| DNAChange | 0..1 | code | DNA-Veränderung | |
| ProteinChange | 0..1 | code | Protein-Veränderung | |
| TypAlteration | 0..1 | code | Typ der Alteration | |
| KomplexeAlteration | 0..1 | string | Komplexe Alteration | |
| SystemischeVortherapien | 0..* | BackboneElement | Systemische Vortherapien | |
 ArtTherapie | 1..1 | code | Bezug zur operativen Therapie | |
| IntentionTherapie | 0..1 | code | Intention | |
| Substanz | 0..* | code | Substanz | |
| Therapiestart | 0..1 | date | Startdatum | |
| Therapieende | 0..1 | date | Enddatum | |
| EndeGrund | 0..1 | code | Ende der Therapie | |
| TherapieAnsprechen | 0..1 | code | Ansprechen | |
| TherapieAnsprechenDatum | 0..1 | date | Datum | |
| OnkologieMolekular | 0..* | BackboneElement | Molekulare Diagnostik | |
| EinfacheVariante | 0..* | BackboneElement | Einfache Variante inkl. Fusionen im codierenden Bereich | |
| Identifier | 0..1 | string | Identifier | |
| Gen | 1..1 | code | Gen | |
| Transkript | 0..1 | code | Transkript | |
| DNAChange | 0..1 | code | DNA-Veränderung | |
| ProteinChange | 0..1 | code | Protein-Veränderung | |
| TypAlteration | 0..1 | code | Typ der Alteration | |
| Lokalization | 0..1 | code | Lokalisation der Variante | |
| LossOfHeterozygosity | 0..1 | code | Loss of Heterozygosity (LOH) | |
| CopyNumberVariante | 0..* | BackboneElement | Variante mit Kopienzahlveränderung (Copy Number Variation, CNV) | |
| Identifier | 0..1 | string | Identifier | |
| CNVTyp | 0..* | BackboneElement | CNV-Typ | |
| Quellprobe | 0..1 | code | Art der Quellprobe | |
| Gen | 0..1 | code | Gen | |
| Chromosom | 0..1 | code | Chromosom | |
| CNVStartPosition | 0..1 | integer | CNV-Start | |
| CNVEndPosition | 0..1 | integer | CNV-Ende | |
| CopyNumber | 0..1 | integer | Copy Number | |
| Lokalization | 0..1 | code | Lokalisation der Variante | |
| StrukturelleVariante | 0..* | BackboneElement | Strukturelle Variante | |
| Identifier | 0..1 | string | Identifier | |
| Quellprobe | 0..1 | code | Art der Quellprobe | |
| Gen | 0..1 | code | Gen | |
| GenC | 0..1 | code | Gen | |
| StrukturTyp | 0..1 | code | Variantentyp | |
| Beschreibung | 0..1 | code | Beschreibung der Variante | |
| Nachweismethode | 0..1 | code | Nachweismethode | |
| Lokalization | 0..1 | code | Lokalisation der Variante | |
| ExpressionsVariante | 0..* | BackboneElement | Expressionsvariante | |
| Identifier | 0..1 | string | Identifier | |
| Gen | 1..1 | code | Gen | |
| Expression | 0..1 | code | Expression | |
| Bewertungsgrundlage | 0..1 | string | Bewertungsgrundlage | |
| TMB | 0..1 | decimal | Tumor Mutational Burden (TMB) | |
| HRD | 0..1 | code | Homologous Recombination Deficiency (HRD) | |
| LST | 0..1 | code | Large Scale Transition (LST) | |
| TAI | 0..1 | code | Telomeric Allelic Imbalance (TAI) | |
| SBS | 0..1 | code | Single Base Substitution (SBS) | |
| SBSSignature | 0..1 | code | Single Base Substitution Signature | |
| Lokalization | 0..1 | code | Lokalisation der Variante | |
| OnkologiePlan | 0..* | BackboneElement | Therapieplan | |
| MolekularesTumorboard | 0..* | BackboneElement | Molekulares Tumorboard | |
| Datum | 1..1 | date | Datum | |
| EmpfehlungStudie | 0..1 | code | Empfehlung Studie | |
| EmpfehlungBeratung | 0..1 | code | Empfehlung humangenetische Beratung | |
| EmpfehlungReevaluation | 0..1 | code | Empfehlung Reevaluation | |
| EmpfehlungOperation | 0..1 | code | Empfehlung Operation | |
| EmpfehlungOperationArt | 0..1 | code | empfohlenene Operation | |
| EmpfehlungOperationRisikoreduzierend | 0..1 | code | empfohlene Operation ist riskoreduzierend | |
| EmpfehlungOperationTherapeutisch | 0..1 | code | empfohlene Operation ist therapeutisch | |
| DurchgefuehrteOperation | 0..* | code | Durchgeführte Operation | |
| EmpfohleneStudie | 0..* | BackboneElement | Empfohlene Studieneinschlüsse | |
| Identifier | 0..1 | string | Identifier | |
| Register | 0..1 | code | Register | |
| StudienID | 0..1 | code | Studie | |
| Studienname | 1..1 | string | Name der Studie | |
| Substanzen | 0..* | code | Substanzen | |
| Evidenzgrad | 0..1 | code | Evidenzgrad | |
| ZusatzverweiseEvidenzgraduierung | 0..* | string | Zusatzverweise zur Evidenzgraduierung | |
| Prioritaet | 0..1 | code | Priorität | |
| Variante | 0..* | code | Variante | |
| Therapieempfehlung | 0..* | BackboneElement | String | |
| Identifier | 0..1 | string | Identifier | |
| EmpfehlungTyp | 0..1 | code | Typ der Empfehlung | |
| Substanz | 0..* | code | Substanzen | |
| Evidenzgrad | 0..1 | code | Evidenzgrad | |
| Prioritaet | 0..1 | code | Priorität | |
| Variante | 0..* | code | Variante | |
| TherapeutischeStrategie | 0..1 | code | Therapeutische Strategie | |
| PraeventiveUntersuchungen | 0..* | BackboneElement | Präventive Maßnahmen | |
| Identifier | 0..1 | string | Identifier | |
| ArtUntersuchung | 0..1 | string | Art der Untersuchung | |
| OnkologieFollowup | 0..* | BackboneElement | Follow-up und Umsetzung der Therapieempfehlung | |
| Datum | 1..1 | date | Datum | |
| MetachroneTumore | 0..* | code | Auftreten Metachroner Tumore | |
| MetachroneDiagnose | 1..1 | code | Diagnose | |
| ECOG | 0..1 | code | ECOG-Status | |
| Vitalstatus | 1..1 | code | Vitalstatus | |
| LetzterKontakt | 0..1 | date | Letzter Kontakt | |
| Todesdatum | 0..1 | date | Todesdatum | |
| Therapien | 0..* | BackboneElement | Therapien | |
| reference | 1..1 | string | Referenz Studien-/ Therapieempfehlung | |
| TherapieStart | 0..1 | date | Startdatum | |
| TherapieEnde | 0..1 | date | Enddatum | |
| TherapieWirkstoff | 0..* | code | Wirkstoff | |
| TherapieAnsprechen | 0..1 | code | Ansprechen | |
| TherapieAnsprechenDatum | 0..1 | date | Datum | |
| TherapieEndeGrund | 0..1 | code | Ende der Therapie | |
| DatenquelleTherapieansprechen | 1..1 | string | Datenquelle Therapieansprechen | |
| PraeventiveMassnahmen | 0..* | BackboneElement | Präventive Maßnahmen | |
| reference | 1..1 | string | Referenz präventive Maßnahme | |
| preventiveMeasureResult | 1..1 | string | Ergebnis der präventiven Maßnahme | |
| preventiveMeasureDate | 0..1 | date | Datum der präventiven Maßnahme | |
| Documentation for this format | ||||
German
Generated Narrative: StructureDefinition mii-lm-mvgenomseq-onkologie
| Name | Flags | Card. | Type | Description & Constraints |
|---|---|---|---|---|
| mii-lm-mvgenomseq-onkologie | 0..* | Element | MII LM Modellvorhaben Genomsequenzierung Onkologie Elements defined in Ancestors:@id, extension | |
| OnkologieFall | 0..* | BackboneElement | Onkologie-Fall | |
| Diagnose | 1..1 | BackboneElement | Diagnose | |
| Haupttumordiagnose | 1..1 | code | Haupttumordiagnose | |
| WeitereOnkologischeDiagnosen | 0..* | code | Weitere onkologische Diagnosen | |
| Hauptdiagnosedatum | 0..1 | date | Hauptdiagnosedatum | |
| ECOGStatus | 0..1 | code | ECOG-Status | |
| KeimbahndiagnoseVorhanden | 0..1 | code | Keimbahndiagnose vorhanden | |
| Keimbahndiagnose | 0..* | code | Keimbahndiagnose | |
| HPOPhaenotypisierung | 0..* | code | Phänotypisierung nach HPO | |
| Histologie | 1..1 | code | Histologie nach ICD-O-3 | |
| Topographie | 1..1 | code | Topographie nach ICD-O-3 | |
| Grading | 0..1 | code | Differenzierungsgrad | |
| TNMSchluessel | 0..1 | string | TNM-Klassifikation | |
| TNMSystematik | 0..1 | code | TNM-Systematik | |
| WeitereKlassifikationen | 0..* | string | Weitere Klassifikationen | |
| DiagnostischeVoruntersuchungen | 0..* | code | Diagnostische Voruntersuchungen | |
| Vordiagnostik | 0..* | BackboneElement | Vordiagnostik | |
| ArtDiagnostik | 1..1 | code | Diagnostik | |
| DatumDiagnostik | 0..1 | date | Datum | |
| MolekulareVorbefunde | 0..* | BackboneElement | klinisch relevante Ergebnisse der Diagnostik | |
| Gen | 1..1 | code | Gen | |
| Transkript | 0..1 | code | Transkript | |
| DNAChange | 0..1 | code | DNA-Veränderung | |
| ProteinChange | 0..1 | code | Protein-Veränderung | |
| TypAlteration | 0..1 | code | Typ der Alteration | |
| KomplexeAlteration | 0..1 | string | Komplexe Alteration | |
| SystemischeVortherapien | 0..* | BackboneElement | Systemische Vortherapien | |
| ArtTherapie | 1..1 | code | Bezug zur operativen Therapie | |
| IntentionTherapie | 0..1 | code | Intention | |
| Substanz | 0..* | code | Substanz | |
| Therapiestart | 0..1 | date | Startdatum | |
| Therapieende | 0..1 | date | Enddatum | |
| EndeGrund | 0..1 | code | Ende der Therapie | |
| TherapieAnsprechen | 0..1 | code | Ansprechen | |
| TherapieAnsprechenDatum | 0..1 | date | Datum | |
| OnkologieMolekular | 0..* | BackboneElement | Molekulare Diagnostik | |
| EinfacheVariante | 0..* | BackboneElement | Einfache Variante inkl. Fusionen im codierenden Bereich | |
| Identifier | 0..1 | string | Identifier | |
| Gen | 1..1 | code | Gen | |
| Transkript | 0..1 | code | Transkript | |
| DNAChange | 0..1 | code | DNA-Veränderung | |
| ProteinChange | 0..1 | code | Protein-Veränderung | |
| TypAlteration | 0..1 | code | Typ der Alteration | |
| Lokalization | 0..1 | code | Lokalisation der Variante | |
| LossOfHeterozygosity | 0..1 | code | Loss of Heterozygosity (LOH) | |
| CopyNumberVariante | 0..* | BackboneElement | Variante mit Kopienzahlveränderung (Copy Number Variation, CNV) | |
| Identifier | 0..1 | string | Identifier | |
| CNVTyp | 0..* | BackboneElement | CNV-Typ | |
| Quellprobe | 0..1 | code | Art der Quellprobe | |
| Gen | 0..1 | code | Gen | |
| Chromosom | 0..1 | code | Chromosom | |
| CNVStartPosition | 0..1 | integer | CNV-Start | |
| CNVEndPosition | 0..1 | integer | CNV-Ende | |
| CopyNumber | 0..1 | integer | Copy Number | |
| Lokalization | 0..1 | code | Lokalisation der Variante | |
| StrukturelleVariante | 0..* | BackboneElement | Strukturelle Variante | |
| Identifier | 0..1 | string | Identifier | |
| Quellprobe | 0..1 | code | Art der Quellprobe | |
| Gen | 0..1 | code | Gen | |
| GenC | 0..1 | code | Gen | |
| StrukturTyp | 0..1 | code | Variantentyp | |
| Beschreibung | 0..1 | code | Beschreibung der Variante | |
| Nachweismethode | 0..1 | code | Nachweismethode | |
| Lokalization | 0..1 | code | Lokalisation der Variante | |
| ExpressionsVariante | 0..* | BackboneElement | Expressionsvariante | |
| Identifier | 0..1 | string | Identifier | |
| Gen | 1..1 | code | Gen | |
| Expression | 0..1 | code | Expression | |
| Bewertungsgrundlage | 0..1 | string | Bewertungsgrundlage | |
| TMB | 0..1 | decimal | Tumor Mutational Burden (TMB) | |
| HRD | 0..1 | code | Homologous Recombination Deficiency (HRD) | |
| LST | 0..1 | code | Large Scale Transition (LST) | |
| TAI | 0..1 | code | Telomeric Allelic Imbalance (TAI) | |
| SBS | 0..1 | code | Single Base Substitution (SBS) | |
| SBSSignature | 0..1 | code | Single Base Substitution Signature | |
| Lokalization | 0..1 | code | Lokalisation der Variante | |
| OnkologiePlan | 0..* | BackboneElement | Therapieplan | |
| MolekularesTumorboard | 0..* | BackboneElement | Molekulares Tumorboard | |
| Datum | 1..1 | date | Datum | |
| EmpfehlungStudie | 0..1 | code | Empfehlung Studie | |
| EmpfehlungBeratung | 0..1 | code | Empfehlung humangenetische Beratung | |
| EmpfehlungReevaluation | 0..1 | code | Empfehlung Reevaluation | |
| EmpfehlungOperation | 0..1 | code | Empfehlung Operation | |
| EmpfehlungOperationArt | 0..1 | code | empfohlenene Operation | |
| EmpfehlungOperationRisikoreduzierend | 0..1 | code | empfohlene Operation ist riskoreduzierend | |
| EmpfehlungOperationTherapeutisch | 0..1 | code | empfohlene Operation ist therapeutisch | |
| DurchgefuehrteOperation | 0..* | code | Durchgeführte Operation | |
| EmpfohleneStudie | 0..* | BackboneElement | Empfohlene Studieneinschlüsse | |
| Identifier | 0..1 | string | Identifier | |
| Register | 0..1 | code | Register | |
| StudienID | 0..1 | code | Studie | |
| Studienname | 1..1 | string | Name der Studie | |
| Substanzen | 0..* | code | Substanzen | |
| Evidenzgrad | 0..1 | code | Evidenzgrad | |
| ZusatzverweiseEvidenzgraduierung | 0..* | string | Zusatzverweise zur Evidenzgraduierung | |
| Prioritaet | 0..1 | code | Priorität | |
| Variante | 0..* | code | Variante | |
| Therapieempfehlung | 0..* | BackboneElement | String | |
| Identifier | 0..1 | string | Identifier | |
| EmpfehlungTyp | 0..1 | code | Typ der Empfehlung | |
| Substanz | 0..* | code | Substanzen | |
| Evidenzgrad | 0..1 | code | Evidenzgrad | |
| Prioritaet | 0..1 | code | Priorität | |
| Variante | 0..* | code | Variante | |
| TherapeutischeStrategie | 0..1 | code | Therapeutische Strategie | |
| PraeventiveUntersuchungen | 0..* | BackboneElement | Präventive Maßnahmen | |
| Identifier | 0..1 | string | Identifier | |
| ArtUntersuchung | 0..1 | string | Art der Untersuchung | |
| OnkologieFollowup | 0..* | BackboneElement | Follow-up und Umsetzung der Therapieempfehlung | |
| Datum | 1..1 | date | Datum | |
| MetachroneTumore | 0..* | code | Auftreten Metachroner Tumore | |
| MetachroneDiagnose | 1..1 | code | Diagnose | |
| ECOG | 0..1 | code | ECOG-Status | |
| Vitalstatus | 1..1 | code | Vitalstatus | |
| LetzterKontakt | 0..1 | date | Letzter Kontakt | |
| Todesdatum | 0..1 | date | Todesdatum | |
| Therapien | 0..* | BackboneElement | Therapien | |
| reference | 1..1 | string | Referenz Studien-/ Therapieempfehlung | |
| TherapieStart | 0..1 | date | Startdatum | |
| TherapieEnde | 0..1 | date | Enddatum | |
| TherapieWirkstoff | 0..* | code | Wirkstoff | |
| TherapieAnsprechen | 0..1 | code | Ansprechen | |
| TherapieAnsprechenDatum | 0..1 | date | Datum | |
| TherapieEndeGrund | 0..1 | code | Ende der Therapie | |
| DatenquelleTherapieansprechen | 1..1 | string | Datenquelle Therapieansprechen | |
| PraeventiveMassnahmen | 0..* | BackboneElement | Präventive Maßnahmen | |
| reference | 1..1 | string | Referenz präventive Maßnahme | |
| preventiveMeasureResult | 1..1 | string | Ergebnis der präventiven Maßnahme | |
| preventiveMeasureDate | 0..1 | date | Datum der präventiven Maßnahme | |
| Documentation for this format | ||||
FHIR
FHIRsmith{
"resourceType": "StructureDefinition",
"id": "mii-lm-mvgenomseq-onkologie",
"meta": {
"extension": [
{
"url": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-license",
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{
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"url": "packageId",
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{
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],
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}
],
"profile": [
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},
"text": {
"status": "extensions",
"div": "<!-- snip (see above) -->"
},
"extension": [
{
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{
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{
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},
{
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"valueCodeableConcept": {
"coding": [
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{
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},
{
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{
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"valueContactDetail": {
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"valueContactDetail": {
"name": "Taskforce Core Data Set"
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},
{
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"valueContactDetail": {
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"telecom": [
{
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]
}
},
{
"url": "http://hl7.org/fhir/StructureDefinition/artifact-reviewer",
"valueContactDetail": {
"name": "National Steering Committee",
"telecom": [
{
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]
}
},
{
"url": "http://hl7.org/fhir/StructureDefinition/artifact-endorser",
"valueContactDetail": {
"name": "Interoperability Working Group",
"telecom": [
{
"system": "url",
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}
},
{
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"valueContactDetail": {
"name": "National Steering Committee",
"telecom": [
{
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}
]
}
},
{
"url": "http://hl7.org/fhir/StructureDefinition/artifact-versionAlgorithm",
"valueCoding": {
"system": "http://hl7.org/fhir/version-algorithm",
"code": "semver",
"display": "SemVer"
}
},
{
"url": "http://hl7.org/fhir/StructureDefinition/resource-effectivePeriod",
"valuePeriod": {
"start": "2027"
}
}
],
"url": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-lm-mvgenomseq-onkologie",
"version": "2027.0.0-ballot.1",
"name": "MII_LM_MVGenomSeq_Onkologie",
"title": "MII LM Modellvorhaben Genomsequenzierung Onkologie",
"status": "active",
"experimental": false,
"date": "2026-09-15T06:26:59+00:00",
"publisher": "Medizininformatik Initiative",
"contact": [
{
"name": "Medizininformatik Initiative",
"telecom": [
{
"system": "url",
"value": "https://www.medizininformatik-initiative.de/"
}
]
}
],
"description": "MII LogicalModel Modellvorhaben Genomsequenzierung Onkologie",
"jurisdiction": [
{
"coding": [
{
"system": "urn:iso:std:iso:3166",
"code": "DE",
"display": "Germany"
}
]
}
],
"fhirVersion": "4.0.1",
"mapping": [
{
"identity": "MVGenomSeq-Datenkranz-to-MII-FHIR",
"name": "Onkologie LogicalModel MII Onkologie Mapping"
}
],
"kind": "logical",
"abstract": false,
"type": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-lm-mvgenomseq-onkologie",
"baseDefinition": "http://hl7.org/fhir/StructureDefinition/Element",
"derivation": "specialization",
"snapshot": {
"extension": [
{
"url": "http://hl7.org/fhir/tools/StructureDefinition/snapshot-base-version",
"valueString": "4.0.1"
}
],
"element": [
{
"id": "mii-lm-mvgenomseq-onkologie",
"path": "mii-lm-mvgenomseq-onkologie",
"short": "MII LM Modellvorhaben Genomsequenzierung Onkologie",
"definition": "MII LogicalModel Modellvorhaben Genomsequenzierung Onkologie",
"min": 0,
"max": "*",
"base": {
"path": "Element",
"min": 0,
"max": "*"
},
"condition": [
"ele-1"
],
"constraint": [
{
"key": "ele-1",
"severity": "error",
"human": "All FHIR elements must have a @value or children",
"expression": "hasValue() or (children().count() > id.count())",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element"
}
],
"isModifier": false,
"mapping": [
{
"identity": "rim",
"map": "n/a"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.id",
"path": "mii-lm-mvgenomseq-onkologie.id",
"representation": [
"xmlAttr"
],
"short": "Unique id for inter-element referencing",
"definition": "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.",
"min": 0,
"max": "1",
"base": {
"path": "Element.id",
"min": 0,
"max": "1"
},
"type": [
{
"extension": [
{
"url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
"valueUrl": "string"
}
],
"code": "http://hl7.org/fhirpath/System.String"
}
],
"isModifier": false,
"isSummary": false,
"mapping": [
{
"identity": "rim",
"map": "n/a"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.extension",
"path": "mii-lm-mvgenomseq-onkologie.extension",
"slicing": {
"discriminator": [
{
"type": "value",
"path": "url"
}
],
"description": "Extensions are always sliced by (at least) url",
"rules": "open"
},
"short": "Additional content defined by implementations",
"definition": "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.",
"comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
"alias": [
"extensions",
"user content"
],
"min": 0,
"max": "*",
"base": {
"path": "Element.extension",
"min": 0,
"max": "*"
},
"type": [
{
"code": "Extension"
}
],
"constraint": [
{
"key": "ele-1",
"severity": "error",
"human": "All FHIR elements must have a @value or children",
"expression": "hasValue() or (children().count() > id.count())",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element"
},
{
"key": "ext-1",
"severity": "error",
"human": "Must have either extensions or value[x], not both",
"expression": "extension.exists() != value.exists()",
"xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
"source": "http://hl7.org/fhir/StructureDefinition/Extension"
}
],
"isModifier": false,
"isSummary": false,
"mapping": [
{
"identity": "rim",
"map": "n/a"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFall",
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall",
"short": "Onkologie-Fall",
"definition": "Onkologie-Fall",
"min": 0,
"max": "*",
"base": {
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall",
"min": 0,
"max": "*"
},
"type": [
{
"code": "BackboneElement"
}
],
"constraint": [
{
"key": "ele-1",
"severity": "error",
"human": "All FHIR elements must have a @value or children",
"expression": "hasValue() or (children().count() > id.count())",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFall.id",
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.id",
"representation": [
"xmlAttr"
],
"short": "Unique id for inter-element referencing",
"definition": "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.",
"min": 0,
"max": "1",
"base": {
"path": "Element.id",
"min": 0,
"max": "1"
},
"type": [
{
"extension": [
{
"url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
"valueUrl": "string"
}
],
"code": "http://hl7.org/fhirpath/System.String"
}
],
"isModifier": false,
"isSummary": false,
"mapping": [
{
"identity": "rim",
"map": "n/a"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFall.extension",
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.extension",
"slicing": {
"discriminator": [
{
"type": "value",
"path": "url"
}
],
"description": "Extensions are always sliced by (at least) url",
"rules": "open"
},
"short": "Additional content defined by implementations",
"definition": "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.",
"comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
"alias": [
"extensions",
"user content"
],
"min": 0,
"max": "*",
"base": {
"path": "Element.extension",
"min": 0,
"max": "*"
},
"type": [
{
"code": "Extension"
}
],
"constraint": [
{
"key": "ele-1",
"severity": "error",
"human": "All FHIR elements must have a @value or children",
"expression": "hasValue() or (children().count() > id.count())",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element"
},
{
"key": "ext-1",
"severity": "error",
"human": "Must have either extensions or value[x], not both",
"expression": "extension.exists() != value.exists()",
"xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
"source": "http://hl7.org/fhir/StructureDefinition/Extension"
}
],
"isModifier": false,
"isSummary": false,
"mapping": [
{
"identity": "rim",
"map": "n/a"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFall.modifierExtension",
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.modifierExtension",
"short": "Extensions that cannot be ignored even if unrecognized",
"definition": "May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.\n\nModifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).",
"comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
"requirements": "Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](http://hl7.org/fhir/R4/extensibility.html#modifierExtension).",
"alias": [
"extensions",
"user content",
"modifiers"
],
"min": 0,
"max": "*",
"base": {
"path": "BackboneElement.modifierExtension",
"min": 0,
"max": "*"
},
"type": [
{
"code": "Extension"
}
],
"constraint": [
{
"key": "ele-1",
"severity": "error",
"human": "All FHIR elements must have a @value or children",
"expression": "hasValue() or (children().count() > id.count())",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element"
},
{
"key": "ext-1",
"severity": "error",
"human": "Must have either extensions or value[x], not both",
"expression": "extension.exists() != value.exists()",
"xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
"source": "http://hl7.org/fhir/StructureDefinition/Extension"
}
],
"isModifier": true,
"isModifierReason": "Modifier extensions are expected to modify the meaning or interpretation of the element that contains them",
"isSummary": true,
"mapping": [
{
"identity": "rim",
"map": "N/A"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFall.Diagnose",
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.Diagnose",
"short": "Diagnose",
"definition": "Diagnose",
"min": 1,
"max": "1",
"base": {
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.Diagnose",
"min": 1,
"max": "1"
},
"type": [
{
"code": "BackboneElement"
}
],
"constraint": [
{
"key": "ele-1",
"severity": "error",
"human": "All FHIR elements must have a @value or children",
"expression": "hasValue() or (children().count() > id.count())",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element"
}
],
"mapping": [
{
"identity": "MVGenomSeq-Datenkranz-to-MII-FHIR",
"map": "Condition"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFall.Diagnose.id",
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.Diagnose.id",
"representation": [
"xmlAttr"
],
"short": "Unique id for inter-element referencing",
"definition": "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.",
"min": 0,
"max": "1",
"base": {
"path": "Element.id",
"min": 0,
"max": "1"
},
"type": [
{
"extension": [
{
"url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
"valueUrl": "string"
}
],
"code": "http://hl7.org/fhirpath/System.String"
}
],
"isModifier": false,
"isSummary": false,
"mapping": [
{
"identity": "rim",
"map": "n/a"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFall.Diagnose.extension",
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.Diagnose.extension",
"slicing": {
"discriminator": [
{
"type": "value",
"path": "url"
}
],
"description": "Extensions are always sliced by (at least) url",
"rules": "open"
},
"short": "Additional content defined by implementations",
"definition": "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.",
"comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
"alias": [
"extensions",
"user content"
],
"min": 0,
"max": "*",
"base": {
"path": "Element.extension",
"min": 0,
"max": "*"
},
"type": [
{
"code": "Extension"
}
],
"constraint": [
{
"key": "ele-1",
"severity": "error",
"human": "All FHIR elements must have a @value or children",
"expression": "hasValue() or (children().count() > id.count())",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element"
},
{
"key": "ext-1",
"severity": "error",
"human": "Must have either extensions or value[x], not both",
"expression": "extension.exists() != value.exists()",
"xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
"source": "http://hl7.org/fhir/StructureDefinition/Extension"
}
],
"isModifier": false,
"isSummary": false,
"mapping": [
{
"identity": "rim",
"map": "n/a"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFall.Diagnose.modifierExtension",
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.Diagnose.modifierExtension",
"short": "Extensions that cannot be ignored even if unrecognized",
"definition": "May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.\n\nModifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).",
"comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
"requirements": "Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](http://hl7.org/fhir/R4/extensibility.html#modifierExtension).",
"alias": [
"extensions",
"user content",
"modifiers"
],
"min": 0,
"max": "*",
"base": {
"path": "BackboneElement.modifierExtension",
"min": 0,
"max": "*"
},
"type": [
{
"code": "Extension"
}
],
"constraint": [
{
"key": "ele-1",
"severity": "error",
"human": "All FHIR elements must have a @value or children",
"expression": "hasValue() or (children().count() > id.count())",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element"
},
{
"key": "ext-1",
"severity": "error",
"human": "Must have either extensions or value[x], not both",
"expression": "extension.exists() != value.exists()",
"xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
"source": "http://hl7.org/fhir/StructureDefinition/Extension"
}
],
"isModifier": true,
"isModifierReason": "Modifier extensions are expected to modify the meaning or interpretation of the element that contains them",
"isSummary": true,
"mapping": [
{
"identity": "rim",
"map": "N/A"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFall.Diagnose.Haupttumordiagnose",
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.Diagnose.Haupttumordiagnose",
"short": "Haupttumordiagnose",
"definition": "Haupttumordiagnose in ICD-10-GM",
"min": 1,
"max": "1",
"base": {
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.Diagnose.Haupttumordiagnose",
"min": 1,
"max": "1"
},
"type": [
{
"code": "code"
}
],
"mapping": [
{
"identity": "MVGenomSeq-Datenkranz-to-MII-FHIR",
"map": "Condition.code.coding.where(system='http://fhir.de/CodeSystem/bfarm/icd-10-gm').code"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFall.Diagnose.WeitereOnkologischeDiagnosen",
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.Diagnose.WeitereOnkologischeDiagnosen",
"short": "Weitere onkologische Diagnosen",
"definition": "Optional bei mehreren onkologischen Diagnosen, insbesondere Dokumentation als weiter onkologische Diagnose bei hereditären Tumordispositionssydroms (HT), bei HT zusätzliche Dokumentation ORPHAcode oder AlphaID, ein Code soweit vorhanden ist. Undiagnostizierte Erkrankungen sind mit ORPHA:616874 zu kodieren.",
"min": 0,
"max": "*",
"base": {
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.Diagnose.WeitereOnkologischeDiagnosen",
"min": 0,
"max": "*"
},
"type": [
{
"code": "code"
}
],
"mapping": [
{
"identity": "MVGenomSeq-Datenkranz-to-MII-FHIR",
"map": "Condition.code.coding.where(system='http://fhir.de/CodeSystem/bfarm/icd-10-gm').code"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFall.Diagnose.Hauptdiagnosedatum",
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.Diagnose.Hauptdiagnosedatum",
"short": "Hauptdiagnosedatum",
"definition": "Datum der Erstdiagnose der Hauptdiagnose. Wenn Tag unbekannt -> 15. des Monats",
"min": 0,
"max": "1",
"base": {
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.Diagnose.Hauptdiagnosedatum",
"min": 0,
"max": "1"
},
"type": [
{
"code": "date"
}
],
"mapping": [
{
"identity": "MVGenomSeq-Datenkranz-to-MII-FHIR",
"map": "Condition.extension.where(url='http://hl7.org/fhir/StructureDefinition/condition-assertedDate').valueDate"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFall.Diagnose.ECOGStatus",
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.Diagnose.ECOGStatus",
"short": "ECOG-Status",
"definition": "Eastern Cooperative Oncology Group (ECOG) Performance Status nach 0,1,2,3,4,5,unknown, not applicable",
"min": 0,
"max": "1",
"base": {
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.Diagnose.ECOGStatus",
"min": 0,
"max": "1"
},
"type": [
{
"code": "code"
}
],
"mapping": [
{
"identity": "MVGenomSeq-Datenkranz-to-MII-FHIR",
"map": "Observation.where(code='423740007' and system='http://snomed.info/sct').valueCodeableConcept.coding.code"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFall.Diagnose.KeimbahndiagnoseVorhanden",
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.Diagnose.KeimbahndiagnoseVorhanden",
"short": "Keimbahndiagnose vorhanden",
"definition": "Ja, Nein, unbekannt",
"min": 0,
"max": "1",
"base": {
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.Diagnose.KeimbahndiagnoseVorhanden",
"min": 0,
"max": "1"
},
"type": [
{
"code": "code"
}
],
"mapping": [
{
"identity": "MVGenomSeq-Datenkranz-to-MII-FHIR",
"map": "no direct match, vsl. über FHIRPath automatisch generieren, wenn Keimbahndiagnose.exists()"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFall.Diagnose.Keimbahndiagnose",
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.Diagnose.Keimbahndiagnose",
"short": "Keimbahndiagnose",
"definition": "Keimbahndiagnosen nach ICD-10-GM.Bei Diagnose eines hereditären Tumordispositionssydroms als Teil der OE ist verpflichtend anzugeben mit ICD10 und ORPHA oder AlphaID",
"min": 0,
"max": "*",
"base": {
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.Diagnose.Keimbahndiagnose",
"min": 0,
"max": "*"
},
"type": [
{
"code": "code"
}
],
"mapping": [
{
"identity": "MVGenomSeq-Datenkranz-to-MII-FHIR",
"map": "no direct match. Keimbahndiagnose existiert als Konzept nicht, hier könnte / müsste mit Condition.category gearbeitet werden, z.B. SNOMED Hereditary cancer-predisposing syndrome (disorder)"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFall.Diagnose.HPOPhaenotypisierung",
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.Diagnose.HPOPhaenotypisierung",
"short": "Phänotypisierung nach HPO ",
"definition": "Human Phenotype Ontology.Bei Diagnose eines hereditären Tumordispositionssydroms als Teil der OE, wenn vorhanden angeben (optional)",
"min": 0,
"max": "*",
"base": {
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.Diagnose.HPOPhaenotypisierung",
"min": 0,
"max": "*"
},
"type": [
{
"code": "code"
}
],
"mapping": [
{
"identity": "MVGenomSeq-Datenkranz-to-MII-FHIR",
"map": "Observation.where(valueCodeableConcept.coding.system='http://human-phenotype-ontology.org')"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFall.Diagnose.Histologie",
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.Diagnose.Histologie",
"short": "Histologie nach ICD-O-3",
"definition": "Histologische Morphologie und Verhalten nach ICD-O-3",
"min": 1,
"max": "1",
"base": {
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.Diagnose.Histologie",
"min": 1,
"max": "1"
},
"type": [
{
"code": "code"
}
],
"mapping": [
{
"identity": "MVGenomSeq-Datenkranz-to-MII-FHIR",
"map": "Condition.extension.where(url='https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-ex-onko-histology-morphology-behavior-icdo3').valueCodeableConcept.coding.code"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFall.Diagnose.Topographie",
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.Diagnose.Topographie",
"short": "Topographie nach ICD-O-3",
"definition": "Topographie des Tumors nach ICD-O-3",
"min": 1,
"max": "1",
"base": {
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.Diagnose.Topographie",
"min": 1,
"max": "1"
},
"type": [
{
"code": "code"
}
],
"mapping": [
{
"identity": "MVGenomSeq-Datenkranz-to-MII-FHIR",
"map": "Condition.bodySite.coding.code"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFall.Diagnose.Grading",
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.Diagnose.Grading",
"short": "Differenzierungsgrad",
"definition": "Gibt den Differenzierungsgrad des Tumors entsprechend der aktuellen TNM-Auflage an, Bei der Klassifikation sind die einschlägigen Regeln der Literatur (TNM) zu beachten.",
"min": 0,
"max": "1",
"base": {
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.Diagnose.Grading",
"min": 0,
"max": "1"
},
"type": [
{
"code": "code"
}
],
"mapping": [
{
"identity": "MVGenomSeq-Datenkranz-to-MII-FHIR",
"map": "Observation.where(code.coding.code='33732-9' and code.coding.system='http://loinc.org').valueCodeableConcept.coding.code"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFall.Diagnose.TNMSchluessel",
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.Diagnose.TNMSchluessel",
"short": "TNM-Klassifikation",
"definition": "TNM-Klassifikation des Tumors",
"min": 0,
"max": "1",
"base": {
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.Diagnose.TNMSchluessel",
"min": 0,
"max": "1"
},
"type": [
{
"code": "string"
}
],
"mapping": [
{
"identity": "MVGenomSeq-Datenkranz-to-MII-FHIR",
"map": "Observation.where(code.coding.code='33732-9' and code.coding.system='http://snomed.info/sct').valueCodeableConcept.coding.code"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFall.Diagnose.TNMSystematik",
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.Diagnose.TNMSystematik",
"short": "TNM-Systematik",
"definition": "TNM-Systematik nach AJCC oder UICC",
"min": 0,
"max": "1",
"base": {
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.Diagnose.TNMSystematik",
"min": 0,
"max": "1"
},
"type": [
{
"code": "code"
}
],
"mapping": [
{
"identity": "MVGenomSeq-Datenkranz-to-MII-FHIR",
"map": "Laut Krebsregisterdaten nur UICC vorgesehen? kein expiziter Datenpunkt außer Version"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFall.Diagnose.WeitereKlassifikationen",
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.Diagnose.WeitereKlassifikationen",
"short": "Weitere Klassifikationen",
"definition": "Weitere Klassifikationen des Tumors zum Diagnosezeitpunkt",
"min": 0,
"max": "*",
"base": {
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.Diagnose.WeitereKlassifikationen",
"min": 0,
"max": "*"
},
"type": [
{
"code": "string"
}
],
"mapping": [
{
"identity": "MVGenomSeq-Datenkranz-to-MII-FHIR",
"map": "no direkt match - Observation - Nutzung des Profils WeitereKlassifikationen, aber aufgrund der Vielfalt der Klassifikationen keine direkte Zuordnung möglich"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFall.Diagnose.DiagnostischeVoruntersuchungen",
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.Diagnose.DiagnostischeVoruntersuchungen",
"short": "Diagnostische Voruntersuchungen",
"definition": "Diagnostische Voruntersuchungen zum Diagnosezeitpunkt. Bewertung der durchgeführten genetischen Diagnostik, nur für heriditäre Prädispositionssyndrome/ Erbliche Tumore",
"min": 0,
"max": "*",
"base": {
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.Diagnose.DiagnostischeVoruntersuchungen",
"min": 0,
"max": "*"
},
"type": [
{
"code": "code"
}
],
"mapping": [
{
"identity": "MVGenomSeq-Datenkranz-to-MII-FHIR",
"map": "no direkt match"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFall.Vordiagnostik",
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.Vordiagnostik",
"short": "Vordiagnostik",
"definition": "Vordiagnostik",
"min": 0,
"max": "*",
"base": {
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.Vordiagnostik",
"min": 0,
"max": "*"
},
"type": [
{
"code": "BackboneElement"
}
],
"constraint": [
{
"key": "ele-1",
"severity": "error",
"human": "All FHIR elements must have a @value or children",
"expression": "hasValue() or (children().count() > id.count())",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element"
}
],
"mapping": [
{
"identity": "MVGenomSeq-Datenkranz-to-MII-FHIR",
"map": "Vordiagnostik"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFall.Vordiagnostik.id",
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.Vordiagnostik.id",
"representation": [
"xmlAttr"
],
"short": "Unique id for inter-element referencing",
"definition": "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.",
"min": 0,
"max": "1",
"base": {
"path": "Element.id",
"min": 0,
"max": "1"
},
"type": [
{
"extension": [
{
"url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
"valueUrl": "string"
}
],
"code": "http://hl7.org/fhirpath/System.String"
}
],
"isModifier": false,
"isSummary": false,
"mapping": [
{
"identity": "rim",
"map": "n/a"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFall.Vordiagnostik.extension",
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.Vordiagnostik.extension",
"slicing": {
"discriminator": [
{
"type": "value",
"path": "url"
}
],
"description": "Extensions are always sliced by (at least) url",
"rules": "open"
},
"short": "Additional content defined by implementations",
"definition": "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.",
"comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
"alias": [
"extensions",
"user content"
],
"min": 0,
"max": "*",
"base": {
"path": "Element.extension",
"min": 0,
"max": "*"
},
"type": [
{
"code": "Extension"
}
],
"constraint": [
{
"key": "ele-1",
"severity": "error",
"human": "All FHIR elements must have a @value or children",
"expression": "hasValue() or (children().count() > id.count())",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element"
},
{
"key": "ext-1",
"severity": "error",
"human": "Must have either extensions or value[x], not both",
"expression": "extension.exists() != value.exists()",
"xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
"source": "http://hl7.org/fhir/StructureDefinition/Extension"
}
],
"isModifier": false,
"isSummary": false,
"mapping": [
{
"identity": "rim",
"map": "n/a"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFall.Vordiagnostik.modifierExtension",
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.Vordiagnostik.modifierExtension",
"short": "Extensions that cannot be ignored even if unrecognized",
"definition": "May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.\n\nModifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).",
"comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
"requirements": "Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](http://hl7.org/fhir/R4/extensibility.html#modifierExtension).",
"alias": [
"extensions",
"user content",
"modifiers"
],
"min": 0,
"max": "*",
"base": {
"path": "BackboneElement.modifierExtension",
"min": 0,
"max": "*"
},
"type": [
{
"code": "Extension"
}
],
"constraint": [
{
"key": "ele-1",
"severity": "error",
"human": "All FHIR elements must have a @value or children",
"expression": "hasValue() or (children().count() > id.count())",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element"
},
{
"key": "ext-1",
"severity": "error",
"human": "Must have either extensions or value[x], not both",
"expression": "extension.exists() != value.exists()",
"xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
"source": "http://hl7.org/fhir/StructureDefinition/Extension"
}
],
"isModifier": true,
"isModifierReason": "Modifier extensions are expected to modify the meaning or interpretation of the element that contains them",
"isSummary": true,
"mapping": [
{
"identity": "rim",
"map": "N/A"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFall.Vordiagnostik.ArtDiagnostik",
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.Vordiagnostik.ArtDiagnostik",
"short": "Diagnostik",
"definition": "Diagnostik, die vor dem MV Genomseq, durchgeführt wurde (Vorbefunde)",
"min": 1,
"max": "1",
"base": {
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.Vordiagnostik.ArtDiagnostik",
"min": 1,
"max": "1"
},
"type": [
{
"code": "code"
}
],
"mapping": [
{
"identity": "MVGenomSeq-Datenkranz-to-MII-FHIR",
"map": "Diagnoste)"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFall.Vordiagnostik.DatumDiagnostik",
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.Vordiagnostik.DatumDiagnostik",
"short": "Datum",
"definition": "Datum der Diagnostik",
"min": 0,
"max": "1",
"base": {
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.Vordiagnostik.DatumDiagnostik",
"min": 0,
"max": "1"
},
"type": [
{
"code": "date"
}
],
"mapping": [
{
"identity": "MVGenomSeq-Datenkranz-to-MII-FHIR",
"map": "Datum Diagnostik"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFall.MolekulareVorbefunde",
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.MolekulareVorbefunde",
"short": "klinisch relevante Ergebnisse der Diagnostik",
"definition": "klinisch relevante Ergebnisse der Diagnostik",
"min": 0,
"max": "*",
"base": {
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.MolekulareVorbefunde",
"min": 0,
"max": "*"
},
"type": [
{
"code": "BackboneElement"
}
],
"constraint": [
{
"key": "ele-1",
"severity": "error",
"human": "All FHIR elements must have a @value or children",
"expression": "hasValue() or (children().count() > id.count())",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element"
}
],
"mapping": [
{
"identity": "MVGenomSeq-Datenkranz-to-MII-FHIR",
"map": "klinisch relevante Ergebnisse der Diagnostik"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFall.MolekulareVorbefunde.id",
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.MolekulareVorbefunde.id",
"representation": [
"xmlAttr"
],
"short": "Unique id for inter-element referencing",
"definition": "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.",
"min": 0,
"max": "1",
"base": {
"path": "Element.id",
"min": 0,
"max": "1"
},
"type": [
{
"extension": [
{
"url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
"valueUrl": "string"
}
],
"code": "http://hl7.org/fhirpath/System.String"
}
],
"isModifier": false,
"isSummary": false,
"mapping": [
{
"identity": "rim",
"map": "n/a"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFall.MolekulareVorbefunde.extension",
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.MolekulareVorbefunde.extension",
"slicing": {
"discriminator": [
{
"type": "value",
"path": "url"
}
],
"description": "Extensions are always sliced by (at least) url",
"rules": "open"
},
"short": "Additional content defined by implementations",
"definition": "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.",
"comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
"alias": [
"extensions",
"user content"
],
"min": 0,
"max": "*",
"base": {
"path": "Element.extension",
"min": 0,
"max": "*"
},
"type": [
{
"code": "Extension"
}
],
"constraint": [
{
"key": "ele-1",
"severity": "error",
"human": "All FHIR elements must have a @value or children",
"expression": "hasValue() or (children().count() > id.count())",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element"
},
{
"key": "ext-1",
"severity": "error",
"human": "Must have either extensions or value[x], not both",
"expression": "extension.exists() != value.exists()",
"xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
"source": "http://hl7.org/fhir/StructureDefinition/Extension"
}
],
"isModifier": false,
"isSummary": false,
"mapping": [
{
"identity": "rim",
"map": "n/a"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFall.MolekulareVorbefunde.modifierExtension",
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.MolekulareVorbefunde.modifierExtension",
"short": "Extensions that cannot be ignored even if unrecognized",
"definition": "May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.\n\nModifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).",
"comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
"requirements": "Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](http://hl7.org/fhir/R4/extensibility.html#modifierExtension).",
"alias": [
"extensions",
"user content",
"modifiers"
],
"min": 0,
"max": "*",
"base": {
"path": "BackboneElement.modifierExtension",
"min": 0,
"max": "*"
},
"type": [
{
"code": "Extension"
}
],
"constraint": [
{
"key": "ele-1",
"severity": "error",
"human": "All FHIR elements must have a @value or children",
"expression": "hasValue() or (children().count() > id.count())",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element"
},
{
"key": "ext-1",
"severity": "error",
"human": "Must have either extensions or value[x], not both",
"expression": "extension.exists() != value.exists()",
"xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
"source": "http://hl7.org/fhir/StructureDefinition/Extension"
}
],
"isModifier": true,
"isModifierReason": "Modifier extensions are expected to modify the meaning or interpretation of the element that contains them",
"isSummary": true,
"mapping": [
{
"identity": "rim",
"map": "N/A"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFall.MolekulareVorbefunde.Gen",
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.MolekulareVorbefunde.Gen",
"short": "Gen",
"definition": "Gen kodiert nach HGNC",
"min": 1,
"max": "1",
"base": {
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.MolekulareVorbefunde.Gen",
"min": 1,
"max": "1"
},
"type": [
{
"code": "code"
}
],
"mapping": [
{
"identity": "MVGenomSeq-Datenkranz-to-MII-FHIR",
"map": "Genert nach HGNC"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFall.MolekulareVorbefunde.Transkript",
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.MolekulareVorbefunde.Transkript",
"short": "Transkript",
"definition": "Transkript kodiert nach Ensembl/RefSeq",
"min": 0,
"max": "1",
"base": {
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.MolekulareVorbefunde.Transkript",
"min": 0,
"max": "1"
},
"type": [
{
"code": "code"
}
],
"mapping": [
{
"identity": "MVGenomSeq-Datenkranz-to-MII-FHIR",
"map": "Transkriranskript kodiert nach Ensembl/RefSeq"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFall.MolekulareVorbefunde.DNAChange",
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.MolekulareVorbefunde.DNAChange",
"short": "DNA-Veränderung",
"definition": "DNA-Verändung nach cHGVS",
"min": 0,
"max": "1",
"base": {
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.MolekulareVorbefunde.DNAChange",
"min": 0,
"max": "1"
},
"type": [
{
"code": "code"
}
],
"mapping": [
{
"identity": "MVGenomSeq-Datenkranz-to-MII-FHIR",
"map": "DNA-VeränVerändung nach cHGVS"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFall.MolekulareVorbefunde.ProteinChange",
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.MolekulareVorbefunde.ProteinChange",
"short": "Protein-Veränderung",
"definition": "Protein-Veränderung nach pHGVS",
"min": 0,
"max": "1",
"base": {
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.MolekulareVorbefunde.ProteinChange",
"min": 0,
"max": "1"
},
"type": [
{
"code": "code"
}
],
"mapping": [
{
"identity": "MVGenomSeq-Datenkranz-to-MII-FHIR",
"map": "Protein-Verändotein-Veränderung nach pHGVS"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFall.MolekulareVorbefunde.TypAlteration",
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.MolekulareVorbefunde.TypAlteration",
"short": "Typ der Alteration",
"definition": "Typ der Alteration / Variantenklasse nach Sequence ontology (SO)",
"min": 0,
"max": "1",
"base": {
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.MolekulareVorbefunde.TypAlteration",
"min": 0,
"max": "1"
},
"type": [
{
"code": "code"
}
],
"mapping": [
{
"identity": "MVGenomSeq-Datenkranz-to-MII-FHIR",
"map": "Typ der Alteratr Alteration / Variantenklasse nach Sequence ontology (SO)"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFall.MolekulareVorbefunde.KomplexeAlteration",
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.MolekulareVorbefunde.KomplexeAlteration",
"short": "Komplexe Alteration",
"definition": "Ausführliche Beschreibung bei komplexen Alteration z.B. Fusion",
"min": 0,
"max": "1",
"base": {
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.MolekulareVorbefunde.KomplexeAlteration",
"min": 0,
"max": "1"
},
"type": [
{
"code": "string"
}
],
"mapping": [
{
"identity": "MVGenomSeq-Datenkranz-to-MII-FHIR",
"map": "Komplexe AlteratAusführliche Beschreibung"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFall.SystemischeVortherapien",
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.SystemischeVortherapien",
"short": "Systemische Vortherapien",
"definition": "Systemische Vortherapien",
"min": 0,
"max": "*",
"base": {
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.SystemischeVortherapien",
"min": 0,
"max": "*"
},
"type": [
{
"code": "BackboneElement"
}
],
"constraint": [
{
"key": "ele-1",
"severity": "error",
"human": "All FHIR elements must have a @value or children",
"expression": "hasValue() or (children().count() > id.count())",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element"
}
],
"mapping": [
{
"identity": "MVGenomSeq-Datenkranz-to-MII-FHIR",
"map": "Procedure"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFall.SystemischeVortherapien.id",
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.SystemischeVortherapien.id",
"representation": [
"xmlAttr"
],
"short": "Unique id for inter-element referencing",
"definition": "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.",
"min": 0,
"max": "1",
"base": {
"path": "Element.id",
"min": 0,
"max": "1"
},
"type": [
{
"extension": [
{
"url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
"valueUrl": "string"
}
],
"code": "http://hl7.org/fhirpath/System.String"
}
],
"isModifier": false,
"isSummary": false,
"mapping": [
{
"identity": "rim",
"map": "n/a"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFall.SystemischeVortherapien.extension",
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.SystemischeVortherapien.extension",
"slicing": {
"discriminator": [
{
"type": "value",
"path": "url"
}
],
"description": "Extensions are always sliced by (at least) url",
"rules": "open"
},
"short": "Additional content defined by implementations",
"definition": "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.",
"comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
"alias": [
"extensions",
"user content"
],
"min": 0,
"max": "*",
"base": {
"path": "Element.extension",
"min": 0,
"max": "*"
},
"type": [
{
"code": "Extension"
}
],
"constraint": [
{
"key": "ele-1",
"severity": "error",
"human": "All FHIR elements must have a @value or children",
"expression": "hasValue() or (children().count() > id.count())",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element"
},
{
"key": "ext-1",
"severity": "error",
"human": "Must have either extensions or value[x], not both",
"expression": "extension.exists() != value.exists()",
"xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
"source": "http://hl7.org/fhir/StructureDefinition/Extension"
}
],
"isModifier": false,
"isSummary": false,
"mapping": [
{
"identity": "rim",
"map": "n/a"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFall.SystemischeVortherapien.modifierExtension",
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.SystemischeVortherapien.modifierExtension",
"short": "Extensions that cannot be ignored even if unrecognized",
"definition": "May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.\n\nModifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).",
"comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
"requirements": "Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](http://hl7.org/fhir/R4/extensibility.html#modifierExtension).",
"alias": [
"extensions",
"user content",
"modifiers"
],
"min": 0,
"max": "*",
"base": {
"path": "BackboneElement.modifierExtension",
"min": 0,
"max": "*"
},
"type": [
{
"code": "Extension"
}
],
"constraint": [
{
"key": "ele-1",
"severity": "error",
"human": "All FHIR elements must have a @value or children",
"expression": "hasValue() or (children().count() > id.count())",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element"
},
{
"key": "ext-1",
"severity": "error",
"human": "Must have either extensions or value[x], not both",
"expression": "extension.exists() != value.exists()",
"xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
"source": "http://hl7.org/fhir/StructureDefinition/Extension"
}
],
"isModifier": true,
"isModifierReason": "Modifier extensions are expected to modify the meaning or interpretation of the element that contains them",
"isSummary": true,
"mapping": [
{
"identity": "rim",
"map": "N/A"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFall.SystemischeVortherapien.ArtTherapie",
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.SystemischeVortherapien.ArtTherapie",
"short": "Bezug zur operativen Therapie",
"definition": "Bezug der Vortherapie zu einer operativen Therapie, z.B. adjuvant, neoadjuvant",
"min": 1,
"max": "1",
"base": {
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.SystemischeVortherapien.ArtTherapie",
"min": 1,
"max": "1"
},
"type": [
{
"code": "code"
}
],
"mapping": [
{
"identity": "MVGenomSeq-Datenkranz-to-MII-FHIR",
"map": "Procedure.extension.where(url='StellungZurOp')"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFall.SystemischeVortherapien.IntentionTherapie",
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.SystemischeVortherapien.IntentionTherapie",
"short": "Intention",
"definition": "Intention der Vortherapie, z.B. kurativ, palliativ",
"min": 0,
"max": "1",
"base": {
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.SystemischeVortherapien.IntentionTherapie",
"min": 0,
"max": "1"
},
"type": [
{
"code": "code"
}
],
"mapping": [
{
"identity": "MVGenomSeq-Datenkranz-to-MII-FHIR",
"map": "Procedure.extension.where(url='Intention')"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFall.SystemischeVortherapien.Substanz",
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.SystemischeVortherapien.Substanz",
"short": "Substanz",
"definition": "Substanz der Vortherapie nach ATC oder Text bei nicht-ATC-Wirkstoffen",
"min": 0,
"max": "*",
"base": {
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.SystemischeVortherapien.Substanz",
"min": 0,
"max": "*"
},
"type": [
{
"code": "code"
}
],
"mapping": [
{
"identity": "MVGenomSeq-Datenkranz-to-MII-FHIR",
"map": "MedicationStatement.medicationCode.coding[atc-de].code"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFall.SystemischeVortherapien.Therapiestart",
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.SystemischeVortherapien.Therapiestart",
"short": "Startdatum",
"definition": "Startdatum der Vortherapie. Wenn Datum unbekannt, dann 15. des Monats",
"min": 0,
"max": "1",
"base": {
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.SystemischeVortherapien.Therapiestart",
"min": 0,
"max": "1"
},
"type": [
{
"code": "date"
}
],
"mapping": [
{
"identity": "MVGenomSeq-Datenkranz-to-MII-FHIR",
"map": "Procedure.effectivePeriod.start"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFall.SystemischeVortherapien.Therapieende",
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.SystemischeVortherapien.Therapieende",
"short": "Enddatum",
"definition": "Enddatum der Vortherapie. Wenn Datum unbekannt, dann 15. des Monats",
"min": 0,
"max": "1",
"base": {
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.SystemischeVortherapien.Therapieende",
"min": 0,
"max": "1"
},
"type": [
{
"code": "date"
}
],
"mapping": [
{
"identity": "MVGenomSeq-Datenkranz-to-MII-FHIR",
"map": "Procedure.effectivePeriod.end"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFall.SystemischeVortherapien.EndeGrund",
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.SystemischeVortherapien.EndeGrund",
"short": "Ende der Therapie",
"definition": "Grund für das Ende der Vortherapie",
"min": 0,
"max": "1",
"base": {
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.SystemischeVortherapien.EndeGrund",
"min": 0,
"max": "1"
},
"type": [
{
"code": "code"
}
],
"mapping": [
{
"identity": "MVGenomSeq-Datenkranz-to-MII-FHIR",
"map": "Procedure.outcome"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFall.SystemischeVortherapien.TherapieAnsprechen",
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.SystemischeVortherapien.TherapieAnsprechen",
"short": "Ansprechen",
"definition": "Therapieansprechen der fallrelevante, systemische Vortherapie (PD: Progression, SD:Stabile Erkrankung, PR:Partielle Remission, CR:Komplette Remission)",
"min": 0,
"max": "1",
"base": {
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.SystemischeVortherapien.TherapieAnsprechen",
"min": 0,
"max": "1"
},
"type": [
{
"code": "code"
}
],
"mapping": [
{
"identity": "MVGenomSeq-Datenkranz-to-MII-FHIR",
"map": "Verlauf.valueCodeableConcept.coding.code"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFall.SystemischeVortherapien.TherapieAnsprechenDatum",
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.SystemischeVortherapien.TherapieAnsprechenDatum",
"short": "Datum",
"definition": "Datum des Ansprechens der Vortherapie",
"min": 0,
"max": "1",
"base": {
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.SystemischeVortherapien.TherapieAnsprechenDatum",
"min": 0,
"max": "1"
},
"type": [
{
"code": "date"
}
],
"mapping": [
{
"identity": "MVGenomSeq-Datenkranz-to-MII-FHIR",
"map": "Verlauf.effectiveDateTime"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular",
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular",
"short": "Molekulare Diagnostik",
"definition": "Molekulare Diagnostik",
"min": 0,
"max": "*",
"base": {
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular",
"min": 0,
"max": "*"
},
"type": [
{
"code": "BackboneElement"
}
],
"constraint": [
{
"key": "ele-1",
"severity": "error",
"human": "All FHIR elements must have a @value or children",
"expression": "hasValue() or (children().count() > id.count())",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.id",
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.id",
"representation": [
"xmlAttr"
],
"short": "Unique id for inter-element referencing",
"definition": "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.",
"min": 0,
"max": "1",
"base": {
"path": "Element.id",
"min": 0,
"max": "1"
},
"type": [
{
"extension": [
{
"url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
"valueUrl": "string"
}
],
"code": "http://hl7.org/fhirpath/System.String"
}
],
"isModifier": false,
"isSummary": false,
"mapping": [
{
"identity": "rim",
"map": "n/a"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.extension",
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.extension",
"slicing": {
"discriminator": [
{
"type": "value",
"path": "url"
}
],
"description": "Extensions are always sliced by (at least) url",
"rules": "open"
},
"short": "Additional content defined by implementations",
"definition": "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.",
"comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
"alias": [
"extensions",
"user content"
],
"min": 0,
"max": "*",
"base": {
"path": "Element.extension",
"min": 0,
"max": "*"
},
"type": [
{
"code": "Extension"
}
],
"constraint": [
{
"key": "ele-1",
"severity": "error",
"human": "All FHIR elements must have a @value or children",
"expression": "hasValue() or (children().count() > id.count())",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element"
},
{
"key": "ext-1",
"severity": "error",
"human": "Must have either extensions or value[x], not both",
"expression": "extension.exists() != value.exists()",
"xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
"source": "http://hl7.org/fhir/StructureDefinition/Extension"
}
],
"isModifier": false,
"isSummary": false,
"mapping": [
{
"identity": "rim",
"map": "n/a"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.modifierExtension",
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.modifierExtension",
"short": "Extensions that cannot be ignored even if unrecognized",
"definition": "May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.\n\nModifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).",
"comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
"requirements": "Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](http://hl7.org/fhir/R4/extensibility.html#modifierExtension).",
"alias": [
"extensions",
"user content",
"modifiers"
],
"min": 0,
"max": "*",
"base": {
"path": "BackboneElement.modifierExtension",
"min": 0,
"max": "*"
},
"type": [
{
"code": "Extension"
}
],
"constraint": [
{
"key": "ele-1",
"severity": "error",
"human": "All FHIR elements must have a @value or children",
"expression": "hasValue() or (children().count() > id.count())",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element"
},
{
"key": "ext-1",
"severity": "error",
"human": "Must have either extensions or value[x], not both",
"expression": "extension.exists() != value.exists()",
"xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
"source": "http://hl7.org/fhir/StructureDefinition/Extension"
}
],
"isModifier": true,
"isModifierReason": "Modifier extensions are expected to modify the meaning or interpretation of the element that contains them",
"isSummary": true,
"mapping": [
{
"identity": "rim",
"map": "N/A"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.EinfacheVariante",
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.EinfacheVariante",
"short": "Einfache Variante inkl. Fusionen im codierenden Bereich",
"definition": "Einfache Variante inkl. Fusionen im codierenden Bereich",
"min": 0,
"max": "*",
"base": {
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.EinfacheVariante",
"min": 0,
"max": "*"
},
"type": [
{
"code": "BackboneElement"
}
],
"constraint": [
{
"key": "ele-1",
"severity": "error",
"human": "All FHIR elements must have a @value or children",
"expression": "hasValue() or (children().count() > id.count())",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.EinfacheVariante.id",
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.EinfacheVariante.id",
"representation": [
"xmlAttr"
],
"short": "Unique id for inter-element referencing",
"definition": "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.",
"min": 0,
"max": "1",
"base": {
"path": "Element.id",
"min": 0,
"max": "1"
},
"type": [
{
"extension": [
{
"url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
"valueUrl": "string"
}
],
"code": "http://hl7.org/fhirpath/System.String"
}
],
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"isSummary": false,
"mapping": [
{
"identity": "rim",
"map": "n/a"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.EinfacheVariante.extension",
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.EinfacheVariante.extension",
"slicing": {
"discriminator": [
{
"type": "value",
"path": "url"
}
],
"description": "Extensions are always sliced by (at least) url",
"rules": "open"
},
"short": "Additional content defined by implementations",
"definition": "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.",
"comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
"alias": [
"extensions",
"user content"
],
"min": 0,
"max": "*",
"base": {
"path": "Element.extension",
"min": 0,
"max": "*"
},
"type": [
{
"code": "Extension"
}
],
"constraint": [
{
"key": "ele-1",
"severity": "error",
"human": "All FHIR elements must have a @value or children",
"expression": "hasValue() or (children().count() > id.count())",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element"
},
{
"key": "ext-1",
"severity": "error",
"human": "Must have either extensions or value[x], not both",
"expression": "extension.exists() != value.exists()",
"xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
"source": "http://hl7.org/fhir/StructureDefinition/Extension"
}
],
"isModifier": false,
"isSummary": false,
"mapping": [
{
"identity": "rim",
"map": "n/a"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.EinfacheVariante.modifierExtension",
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.EinfacheVariante.modifierExtension",
"short": "Extensions that cannot be ignored even if unrecognized",
"definition": "May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.\n\nModifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).",
"comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
"requirements": "Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](http://hl7.org/fhir/R4/extensibility.html#modifierExtension).",
"alias": [
"extensions",
"user content",
"modifiers"
],
"min": 0,
"max": "*",
"base": {
"path": "BackboneElement.modifierExtension",
"min": 0,
"max": "*"
},
"type": [
{
"code": "Extension"
}
],
"constraint": [
{
"key": "ele-1",
"severity": "error",
"human": "All FHIR elements must have a @value or children",
"expression": "hasValue() or (children().count() > id.count())",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element"
},
{
"key": "ext-1",
"severity": "error",
"human": "Must have either extensions or value[x], not both",
"expression": "extension.exists() != value.exists()",
"xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
"source": "http://hl7.org/fhir/StructureDefinition/Extension"
}
],
"isModifier": true,
"isModifierReason": "Modifier extensions are expected to modify the meaning or interpretation of the element that contains them",
"isSummary": true,
"mapping": [
{
"identity": "rim",
"map": "N/A"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.EinfacheVariante.Identifier",
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.EinfacheVariante.Identifier",
"short": "Identifier",
"definition": "interner Identifikator der Variante",
"min": 0,
"max": "1",
"base": {
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.EinfacheVariante.Identifier",
"min": 0,
"max": "1"
},
"type": [
{
"code": "string"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.EinfacheVariante.Gen",
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.EinfacheVariante.Gen",
"short": "Gen",
"definition": "Gen kodiert nach HGNC",
"min": 1,
"max": "1",
"base": {
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.EinfacheVariante.Gen",
"min": 1,
"max": "1"
},
"type": [
{
"code": "code"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.EinfacheVariante.Transkript",
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.EinfacheVariante.Transkript",
"short": "Transkript",
"definition": "Transkript kodiert nach Ensembl/RefSeq",
"min": 0,
"max": "1",
"base": {
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.EinfacheVariante.Transkript",
"min": 0,
"max": "1"
},
"type": [
{
"code": "code"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.EinfacheVariante.DNAChange",
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.EinfacheVariante.DNAChange",
"short": "DNA-Veränderung",
"definition": "DNA-Verändung nach cHGVS",
"min": 0,
"max": "1",
"base": {
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.EinfacheVariante.DNAChange",
"min": 0,
"max": "1"
},
"type": [
{
"code": "code"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.EinfacheVariante.ProteinChange",
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.EinfacheVariante.ProteinChange",
"short": "Protein-Veränderung",
"definition": "Protein-Veränderung nach pHGVS",
"min": 0,
"max": "1",
"base": {
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.EinfacheVariante.ProteinChange",
"min": 0,
"max": "1"
},
"type": [
{
"code": "code"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.EinfacheVariante.TypAlteration",
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.EinfacheVariante.TypAlteration",
"short": "Typ der Alteration",
"definition": "Typ der Alteration / Variantenklasse nach Sequence ontology (SO)",
"min": 0,
"max": "1",
"base": {
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.EinfacheVariante.TypAlteration",
"min": 0,
"max": "1"
},
"type": [
{
"code": "code"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.EinfacheVariante.Lokalization",
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.EinfacheVariante.Lokalization",
"short": "Lokalisation der Variante",
"definition": "Lokalisation im kodierenden, regulatorischen oder intergenischen Bereich",
"min": 0,
"max": "1",
"base": {
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.EinfacheVariante.Lokalization",
"min": 0,
"max": "1"
},
"type": [
{
"code": "code"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.EinfacheVariante.LossOfHeterozygosity",
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.EinfacheVariante.LossOfHeterozygosity",
"short": "Loss of Heterozygosity (LOH)",
"definition": "Loss of Heterozygosity (LOH) im Bereich der Variante Ja / Nein",
"min": 0,
"max": "1",
"base": {
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.EinfacheVariante.LossOfHeterozygosity",
"min": 0,
"max": "1"
},
"type": [
{
"code": "code"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.CopyNumberVariante",
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.CopyNumberVariante",
"short": "Variante mit Kopienzahlveränderung (Copy Number Variation, CNV)",
"definition": "Variante mit Kopienzahlveränderung (Copy Number Variation, CNV)",
"min": 0,
"max": "*",
"base": {
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.CopyNumberVariante",
"min": 0,
"max": "*"
},
"type": [
{
"code": "BackboneElement"
}
],
"constraint": [
{
"key": "ele-1",
"severity": "error",
"human": "All FHIR elements must have a @value or children",
"expression": "hasValue() or (children().count() > id.count())",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.CopyNumberVariante.id",
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.CopyNumberVariante.id",
"representation": [
"xmlAttr"
],
"short": "Unique id for inter-element referencing",
"definition": "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.",
"min": 0,
"max": "1",
"base": {
"path": "Element.id",
"min": 0,
"max": "1"
},
"type": [
{
"extension": [
{
"url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
"valueUrl": "string"
}
],
"code": "http://hl7.org/fhirpath/System.String"
}
],
"isModifier": false,
"isSummary": false,
"mapping": [
{
"identity": "rim",
"map": "n/a"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.CopyNumberVariante.extension",
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.CopyNumberVariante.extension",
"slicing": {
"discriminator": [
{
"type": "value",
"path": "url"
}
],
"description": "Extensions are always sliced by (at least) url",
"rules": "open"
},
"short": "Additional content defined by implementations",
"definition": "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.",
"comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
"alias": [
"extensions",
"user content"
],
"min": 0,
"max": "*",
"base": {
"path": "Element.extension",
"min": 0,
"max": "*"
},
"type": [
{
"code": "Extension"
}
],
"constraint": [
{
"key": "ele-1",
"severity": "error",
"human": "All FHIR elements must have a @value or children",
"expression": "hasValue() or (children().count() > id.count())",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element"
},
{
"key": "ext-1",
"severity": "error",
"human": "Must have either extensions or value[x], not both",
"expression": "extension.exists() != value.exists()",
"xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
"source": "http://hl7.org/fhir/StructureDefinition/Extension"
}
],
"isModifier": false,
"isSummary": false,
"mapping": [
{
"identity": "rim",
"map": "n/a"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.CopyNumberVariante.modifierExtension",
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.CopyNumberVariante.modifierExtension",
"short": "Extensions that cannot be ignored even if unrecognized",
"definition": "May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.\n\nModifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).",
"comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
"requirements": "Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](http://hl7.org/fhir/R4/extensibility.html#modifierExtension).",
"alias": [
"extensions",
"user content",
"modifiers"
],
"min": 0,
"max": "*",
"base": {
"path": "BackboneElement.modifierExtension",
"min": 0,
"max": "*"
},
"type": [
{
"code": "Extension"
}
],
"constraint": [
{
"key": "ele-1",
"severity": "error",
"human": "All FHIR elements must have a @value or children",
"expression": "hasValue() or (children().count() > id.count())",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element"
},
{
"key": "ext-1",
"severity": "error",
"human": "Must have either extensions or value[x], not both",
"expression": "extension.exists() != value.exists()",
"xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
"source": "http://hl7.org/fhir/StructureDefinition/Extension"
}
],
"isModifier": true,
"isModifierReason": "Modifier extensions are expected to modify the meaning or interpretation of the element that contains them",
"isSummary": true,
"mapping": [
{
"identity": "rim",
"map": "N/A"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.CopyNumberVariante.Identifier",
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.CopyNumberVariante.Identifier",
"short": "Identifier",
"definition": "interner Identifikator der Variante",
"min": 0,
"max": "1",
"base": {
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.CopyNumberVariante.Identifier",
"min": 0,
"max": "1"
},
"type": [
{
"code": "string"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.CopyNumberVariante.CNVTyp",
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.CopyNumberVariante.CNVTyp",
"short": "CNV-Typ",
"definition": "Komplettverlust, partieller Verlust, Amplifikation",
"min": 0,
"max": "*",
"base": {
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.CopyNumberVariante.CNVTyp",
"min": 0,
"max": "*"
},
"type": [
{
"code": "BackboneElement"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.CopyNumberVariante.Quellprobe",
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.CopyNumberVariante.Quellprobe",
"short": "Art der Quellprobe",
"definition": "Art der Quellprobe (somatisch oder Keimbahn)",
"min": 0,
"max": "1",
"base": {
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.CopyNumberVariante.Quellprobe",
"min": 0,
"max": "1"
},
"type": [
{
"code": "code"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.CopyNumberVariante.Gen",
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.CopyNumberVariante.Gen",
"short": "Gen",
"definition": "Gen kodiert nach HGNC - falls nur ein Gen betreffend",
"min": 0,
"max": "1",
"base": {
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.CopyNumberVariante.Gen",
"min": 0,
"max": "1"
},
"type": [
{
"code": "code"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.CopyNumberVariante.Chromosom",
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.CopyNumberVariante.Chromosom",
"short": "Chromosom",
"definition": "Chromosom",
"min": 0,
"max": "1",
"base": {
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.CopyNumberVariante.Chromosom",
"min": 0,
"max": "1"
},
"type": [
{
"code": "code"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.CopyNumberVariante.CNVStartPosition",
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.CopyNumberVariante.CNVStartPosition",
"short": "CNV-Start",
"definition": "Startposition des CNV basierend auf Hg38",
"min": 0,
"max": "1",
"base": {
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.CopyNumberVariante.CNVStartPosition",
"min": 0,
"max": "1"
},
"type": [
{
"code": "integer"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.CopyNumberVariante.CNVEndPosition",
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.CopyNumberVariante.CNVEndPosition",
"short": "CNV-Ende",
"definition": "Endposition des CNV basierend auf Hg38",
"min": 0,
"max": "1",
"base": {
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.CopyNumberVariante.CNVEndPosition",
"min": 0,
"max": "1"
},
"type": [
{
"code": "integer"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.CopyNumberVariante.CopyNumber",
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.CopyNumberVariante.CopyNumber",
"short": "Copy Number",
"definition": "Copy Number",
"min": 0,
"max": "1",
"base": {
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.CopyNumberVariante.CopyNumber",
"min": 0,
"max": "1"
},
"type": [
{
"code": "integer"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.CopyNumberVariante.Lokalization",
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.CopyNumberVariante.Lokalization",
"short": "Lokalisation der Variante",
"definition": "Lokalisation im kodierenden, regulatorischen oder intergenischen Bereich",
"min": 0,
"max": "1",
"base": {
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.CopyNumberVariante.Lokalization",
"min": 0,
"max": "1"
},
"type": [
{
"code": "code"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.StrukturelleVariante",
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.StrukturelleVariante",
"short": "Strukturelle Variante",
"definition": "Strukturelle Variante",
"min": 0,
"max": "*",
"base": {
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.StrukturelleVariante",
"min": 0,
"max": "*"
},
"type": [
{
"code": "BackboneElement"
}
],
"constraint": [
{
"key": "ele-1",
"severity": "error",
"human": "All FHIR elements must have a @value or children",
"expression": "hasValue() or (children().count() > id.count())",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.StrukturelleVariante.id",
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.StrukturelleVariante.id",
"representation": [
"xmlAttr"
],
"short": "Unique id for inter-element referencing",
"definition": "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.",
"min": 0,
"max": "1",
"base": {
"path": "Element.id",
"min": 0,
"max": "1"
},
"type": [
{
"extension": [
{
"url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
"valueUrl": "string"
}
],
"code": "http://hl7.org/fhirpath/System.String"
}
],
"isModifier": false,
"isSummary": false,
"mapping": [
{
"identity": "rim",
"map": "n/a"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.StrukturelleVariante.extension",
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.StrukturelleVariante.extension",
"slicing": {
"discriminator": [
{
"type": "value",
"path": "url"
}
],
"description": "Extensions are always sliced by (at least) url",
"rules": "open"
},
"short": "Additional content defined by implementations",
"definition": "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.",
"comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
"alias": [
"extensions",
"user content"
],
"min": 0,
"max": "*",
"base": {
"path": "Element.extension",
"min": 0,
"max": "*"
},
"type": [
{
"code": "Extension"
}
],
"constraint": [
{
"key": "ele-1",
"severity": "error",
"human": "All FHIR elements must have a @value or children",
"expression": "hasValue() or (children().count() > id.count())",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element"
},
{
"key": "ext-1",
"severity": "error",
"human": "Must have either extensions or value[x], not both",
"expression": "extension.exists() != value.exists()",
"xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
"source": "http://hl7.org/fhir/StructureDefinition/Extension"
}
],
"isModifier": false,
"isSummary": false,
"mapping": [
{
"identity": "rim",
"map": "n/a"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.StrukturelleVariante.modifierExtension",
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.StrukturelleVariante.modifierExtension",
"short": "Extensions that cannot be ignored even if unrecognized",
"definition": "May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.\n\nModifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).",
"comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
"requirements": "Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](http://hl7.org/fhir/R4/extensibility.html#modifierExtension).",
"alias": [
"extensions",
"user content",
"modifiers"
],
"min": 0,
"max": "*",
"base": {
"path": "BackboneElement.modifierExtension",
"min": 0,
"max": "*"
},
"type": [
{
"code": "Extension"
}
],
"constraint": [
{
"key": "ele-1",
"severity": "error",
"human": "All FHIR elements must have a @value or children",
"expression": "hasValue() or (children().count() > id.count())",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element"
},
{
"key": "ext-1",
"severity": "error",
"human": "Must have either extensions or value[x], not both",
"expression": "extension.exists() != value.exists()",
"xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
"source": "http://hl7.org/fhir/StructureDefinition/Extension"
}
],
"isModifier": true,
"isModifierReason": "Modifier extensions are expected to modify the meaning or interpretation of the element that contains them",
"isSummary": true,
"mapping": [
{
"identity": "rim",
"map": "N/A"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.StrukturelleVariante.Identifier",
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.StrukturelleVariante.Identifier",
"short": "Identifier",
"definition": "interner Identifikator der Variante",
"min": 0,
"max": "1",
"base": {
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.StrukturelleVariante.Identifier",
"min": 0,
"max": "1"
},
"type": [
{
"code": "string"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.StrukturelleVariante.Quellprobe",
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.StrukturelleVariante.Quellprobe",
"short": "Art der Quellprobe",
"definition": "Art der Quellprobe (somatisch oder Keimbahn)",
"min": 0,
"max": "1",
"base": {
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.StrukturelleVariante.Quellprobe",
"min": 0,
"max": "1"
},
"type": [
{
"code": "code"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.StrukturelleVariante.Gen",
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.StrukturelleVariante.Gen",
"short": "Gen",
"definition": "N-terminales Gen",
"min": 0,
"max": "1",
"base": {
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.StrukturelleVariante.Gen",
"min": 0,
"max": "1"
},
"type": [
{
"code": "code"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.StrukturelleVariante.GenC",
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.StrukturelleVariante.GenC",
"short": "Gen",
"definition": "C-terminales Gen, falls in-frame und kodierend",
"min": 0,
"max": "1",
"base": {
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.StrukturelleVariante.GenC",
"min": 0,
"max": "1"
},
"type": [
{
"code": "code"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.StrukturelleVariante.StrukturTyp",
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.StrukturelleVariante.StrukturTyp",
"short": "Variantentyp",
"definition": "Variantentyp (Inversion, Translokation, Deletion, Insertion, Duplikation)",
"min": 0,
"max": "1",
"base": {
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.StrukturelleVariante.StrukturTyp",
"min": 0,
"max": "1"
},
"type": [
{
"code": "code"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.StrukturelleVariante.Beschreibung",
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.StrukturelleVariante.Beschreibung",
"short": "Beschreibung der Variante",
"definition": "Beschreibung der Variante nach HGVS oder ISCN",
"min": 0,
"max": "1",
"base": {
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.StrukturelleVariante.Beschreibung",
"min": 0,
"max": "1"
},
"type": [
{
"code": "code"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.StrukturelleVariante.Nachweismethode",
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.StrukturelleVariante.Nachweismethode",
"short": "Nachweismethode",
"definition": "Nachweismethode (DNA / RNA)",
"min": 0,
"max": "1",
"base": {
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.StrukturelleVariante.Nachweismethode",
"min": 0,
"max": "1"
},
"type": [
{
"code": "code"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.StrukturelleVariante.Lokalization",
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.StrukturelleVariante.Lokalization",
"short": "Lokalisation der Variante",
"definition": "Lokalisation im kodierenden, regulatorischen oder intergenischen Bereich",
"min": 0,
"max": "1",
"base": {
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.StrukturelleVariante.Lokalization",
"min": 0,
"max": "1"
},
"type": [
{
"code": "code"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.ExpressionsVariante",
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.ExpressionsVariante",
"short": "Expressionsvariante",
"definition": "Expressionsvariante",
"min": 0,
"max": "*",
"base": {
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.ExpressionsVariante",
"min": 0,
"max": "*"
},
"type": [
{
"code": "BackboneElement"
}
],
"constraint": [
{
"key": "ele-1",
"severity": "error",
"human": "All FHIR elements must have a @value or children",
"expression": "hasValue() or (children().count() > id.count())",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.ExpressionsVariante.id",
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.ExpressionsVariante.id",
"representation": [
"xmlAttr"
],
"short": "Unique id for inter-element referencing",
"definition": "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.",
"min": 0,
"max": "1",
"base": {
"path": "Element.id",
"min": 0,
"max": "1"
},
"type": [
{
"extension": [
{
"url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
"valueUrl": "string"
}
],
"code": "http://hl7.org/fhirpath/System.String"
}
],
"isModifier": false,
"isSummary": false,
"mapping": [
{
"identity": "rim",
"map": "n/a"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.ExpressionsVariante.extension",
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.ExpressionsVariante.extension",
"slicing": {
"discriminator": [
{
"type": "value",
"path": "url"
}
],
"description": "Extensions are always sliced by (at least) url",
"rules": "open"
},
"short": "Additional content defined by implementations",
"definition": "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.",
"comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
"alias": [
"extensions",
"user content"
],
"min": 0,
"max": "*",
"base": {
"path": "Element.extension",
"min": 0,
"max": "*"
},
"type": [
{
"code": "Extension"
}
],
"constraint": [
{
"key": "ele-1",
"severity": "error",
"human": "All FHIR elements must have a @value or children",
"expression": "hasValue() or (children().count() > id.count())",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element"
},
{
"key": "ext-1",
"severity": "error",
"human": "Must have either extensions or value[x], not both",
"expression": "extension.exists() != value.exists()",
"xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
"source": "http://hl7.org/fhir/StructureDefinition/Extension"
}
],
"isModifier": false,
"isSummary": false,
"mapping": [
{
"identity": "rim",
"map": "n/a"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.ExpressionsVariante.modifierExtension",
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.ExpressionsVariante.modifierExtension",
"short": "Extensions that cannot be ignored even if unrecognized",
"definition": "May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.\n\nModifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).",
"comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
"requirements": "Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](http://hl7.org/fhir/R4/extensibility.html#modifierExtension).",
"alias": [
"extensions",
"user content",
"modifiers"
],
"min": 0,
"max": "*",
"base": {
"path": "BackboneElement.modifierExtension",
"min": 0,
"max": "*"
},
"type": [
{
"code": "Extension"
}
],
"constraint": [
{
"key": "ele-1",
"severity": "error",
"human": "All FHIR elements must have a @value or children",
"expression": "hasValue() or (children().count() > id.count())",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element"
},
{
"key": "ext-1",
"severity": "error",
"human": "Must have either extensions or value[x], not both",
"expression": "extension.exists() != value.exists()",
"xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
"source": "http://hl7.org/fhir/StructureDefinition/Extension"
}
],
"isModifier": true,
"isModifierReason": "Modifier extensions are expected to modify the meaning or interpretation of the element that contains them",
"isSummary": true,
"mapping": [
{
"identity": "rim",
"map": "N/A"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.ExpressionsVariante.Identifier",
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.ExpressionsVariante.Identifier",
"short": "Identifier",
"definition": "interner Identifikator der Variante",
"min": 0,
"max": "1",
"base": {
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.ExpressionsVariante.Identifier",
"min": 0,
"max": "1"
},
"type": [
{
"code": "string"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.ExpressionsVariante.Gen",
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.ExpressionsVariante.Gen",
"short": "Gen",
"definition": "Gen kodiert nach HGNC",
"min": 1,
"max": "1",
"base": {
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.ExpressionsVariante.Gen",
"min": 1,
"max": "1"
},
"type": [
{
"code": "code"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.ExpressionsVariante.Expression",
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.ExpressionsVariante.Expression",
"short": "Expression",
"definition": "Expression des Gens (über- oder unterexprimiert)",
"min": 0,
"max": "1",
"base": {
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.ExpressionsVariante.Expression",
"min": 0,
"max": "1"
},
"type": [
{
"code": "code"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.ExpressionsVariante.Bewertungsgrundlage",
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.ExpressionsVariante.Bewertungsgrundlage",
"short": "Bewertungsgrundlage",
"definition": "Bewertungsgrundlage der Expression (z.B. Vergleichskohorte von 400 Patienten)",
"min": 0,
"max": "1",
"base": {
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.ExpressionsVariante.Bewertungsgrundlage",
"min": 0,
"max": "1"
},
"type": [
{
"code": "string"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.ExpressionsVariante.TMB",
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.ExpressionsVariante.TMB",
"short": "Tumor Mutational Burden (TMB)",
"definition": "Tumor Mutational Burden (TMB) in Mut/Mb",
"min": 0,
"max": "1",
"base": {
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.ExpressionsVariante.TMB",
"min": 0,
"max": "1"
},
"type": [
{
"code": "decimal"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.ExpressionsVariante.HRD",
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.ExpressionsVariante.HRD",
"short": "Homologous Recombination Deficiency (HRD)",
"definition": "Homologous Recombination Deficiency (HRD) erhöht ja/nein",
"min": 0,
"max": "1",
"base": {
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.ExpressionsVariante.HRD",
"min": 0,
"max": "1"
},
"type": [
{
"code": "code"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.ExpressionsVariante.LST",
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.ExpressionsVariante.LST",
"short": "Large Scale Transition (LST)",
"definition": "Large Scale Transition (LST) erhöht ja/nein",
"min": 0,
"max": "1",
"base": {
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.ExpressionsVariante.LST",
"min": 0,
"max": "1"
},
"type": [
{
"code": "code"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.ExpressionsVariante.TAI",
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.ExpressionsVariante.TAI",
"short": "Telomeric Allelic Imbalance (TAI)",
"definition": "Telomeric Allelic Imbalance (TAI) erhöht ja/nein",
"min": 0,
"max": "1",
"base": {
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.ExpressionsVariante.TAI",
"min": 0,
"max": "1"
},
"type": [
{
"code": "code"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.ExpressionsVariante.SBS",
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.ExpressionsVariante.SBS",
"short": "Single Base Substitution (SBS)",
"definition": "Single Base Substitution (SBS) erhöht ja/nein",
"min": 0,
"max": "1",
"base": {
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.ExpressionsVariante.SBS",
"min": 0,
"max": "1"
},
"type": [
{
"code": "code"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.ExpressionsVariante.SBSSignature",
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.ExpressionsVariante.SBSSignature",
"short": "Single Base Substitution Signature",
"definition": "Single Base Substitution Signature",
"min": 0,
"max": "1",
"base": {
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.ExpressionsVariante.SBSSignature",
"min": 0,
"max": "1"
},
"type": [
{
"code": "code"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.ExpressionsVariante.Lokalization",
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.ExpressionsVariante.Lokalization",
"short": "Lokalisation der Variante",
"definition": "Lokalisation im kodierenden, regulatorischen oder intergenischen Bereich",
"min": 0,
"max": "1",
"base": {
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.ExpressionsVariante.Lokalization",
"min": 0,
"max": "1"
},
"type": [
{
"code": "code"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologiePlan",
"path": "mii-lm-mvgenomseq-onkologie.OnkologiePlan",
"short": "Therapieplan",
"definition": "Therapieplan",
"min": 0,
"max": "*",
"base": {
"path": "mii-lm-mvgenomseq-onkologie.OnkologiePlan",
"min": 0,
"max": "*"
},
"type": [
{
"code": "BackboneElement"
}
],
"constraint": [
{
"key": "ele-1",
"severity": "error",
"human": "All FHIR elements must have a @value or children",
"expression": "hasValue() or (children().count() > id.count())",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.id",
"path": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.id",
"representation": [
"xmlAttr"
],
"short": "Unique id for inter-element referencing",
"definition": "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.",
"min": 0,
"max": "1",
"base": {
"path": "Element.id",
"min": 0,
"max": "1"
},
"type": [
{
"extension": [
{
"url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
"valueUrl": "string"
}
],
"code": "http://hl7.org/fhirpath/System.String"
}
],
"isModifier": false,
"isSummary": false,
"mapping": [
{
"identity": "rim",
"map": "n/a"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.extension",
"path": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.extension",
"slicing": {
"discriminator": [
{
"type": "value",
"path": "url"
}
],
"description": "Extensions are always sliced by (at least) url",
"rules": "open"
},
"short": "Additional content defined by implementations",
"definition": "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.",
"comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
"alias": [
"extensions",
"user content"
],
"min": 0,
"max": "*",
"base": {
"path": "Element.extension",
"min": 0,
"max": "*"
},
"type": [
{
"code": "Extension"
}
],
"constraint": [
{
"key": "ele-1",
"severity": "error",
"human": "All FHIR elements must have a @value or children",
"expression": "hasValue() or (children().count() > id.count())",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element"
},
{
"key": "ext-1",
"severity": "error",
"human": "Must have either extensions or value[x], not both",
"expression": "extension.exists() != value.exists()",
"xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
"source": "http://hl7.org/fhir/StructureDefinition/Extension"
}
],
"isModifier": false,
"isSummary": false,
"mapping": [
{
"identity": "rim",
"map": "n/a"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.modifierExtension",
"path": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.modifierExtension",
"short": "Extensions that cannot be ignored even if unrecognized",
"definition": "May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.\n\nModifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).",
"comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
"requirements": "Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](http://hl7.org/fhir/R4/extensibility.html#modifierExtension).",
"alias": [
"extensions",
"user content",
"modifiers"
],
"min": 0,
"max": "*",
"base": {
"path": "BackboneElement.modifierExtension",
"min": 0,
"max": "*"
},
"type": [
{
"code": "Extension"
}
],
"constraint": [
{
"key": "ele-1",
"severity": "error",
"human": "All FHIR elements must have a @value or children",
"expression": "hasValue() or (children().count() > id.count())",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element"
},
{
"key": "ext-1",
"severity": "error",
"human": "Must have either extensions or value[x], not both",
"expression": "extension.exists() != value.exists()",
"xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
"source": "http://hl7.org/fhir/StructureDefinition/Extension"
}
],
"isModifier": true,
"isModifierReason": "Modifier extensions are expected to modify the meaning or interpretation of the element that contains them",
"isSummary": true,
"mapping": [
{
"identity": "rim",
"map": "N/A"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.MolekularesTumorboard",
"path": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.MolekularesTumorboard",
"short": "Molekulares Tumorboard",
"definition": "Molekulares Tumorboard",
"min": 0,
"max": "*",
"base": {
"path": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.MolekularesTumorboard",
"min": 0,
"max": "*"
},
"type": [
{
"code": "BackboneElement"
}
],
"constraint": [
{
"key": "ele-1",
"severity": "error",
"human": "All FHIR elements must have a @value or children",
"expression": "hasValue() or (children().count() > id.count())",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.MolekularesTumorboard.id",
"path": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.MolekularesTumorboard.id",
"representation": [
"xmlAttr"
],
"short": "Unique id for inter-element referencing",
"definition": "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.",
"min": 0,
"max": "1",
"base": {
"path": "Element.id",
"min": 0,
"max": "1"
},
"type": [
{
"extension": [
{
"url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
"valueUrl": "string"
}
],
"code": "http://hl7.org/fhirpath/System.String"
}
],
"isModifier": false,
"isSummary": false,
"mapping": [
{
"identity": "rim",
"map": "n/a"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.MolekularesTumorboard.extension",
"path": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.MolekularesTumorboard.extension",
"slicing": {
"discriminator": [
{
"type": "value",
"path": "url"
}
],
"description": "Extensions are always sliced by (at least) url",
"rules": "open"
},
"short": "Additional content defined by implementations",
"definition": "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.",
"comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
"alias": [
"extensions",
"user content"
],
"min": 0,
"max": "*",
"base": {
"path": "Element.extension",
"min": 0,
"max": "*"
},
"type": [
{
"code": "Extension"
}
],
"constraint": [
{
"key": "ele-1",
"severity": "error",
"human": "All FHIR elements must have a @value or children",
"expression": "hasValue() or (children().count() > id.count())",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element"
},
{
"key": "ext-1",
"severity": "error",
"human": "Must have either extensions or value[x], not both",
"expression": "extension.exists() != value.exists()",
"xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
"source": "http://hl7.org/fhir/StructureDefinition/Extension"
}
],
"isModifier": false,
"isSummary": false,
"mapping": [
{
"identity": "rim",
"map": "n/a"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.MolekularesTumorboard.modifierExtension",
"path": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.MolekularesTumorboard.modifierExtension",
"short": "Extensions that cannot be ignored even if unrecognized",
"definition": "May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.\n\nModifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).",
"comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
"requirements": "Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](http://hl7.org/fhir/R4/extensibility.html#modifierExtension).",
"alias": [
"extensions",
"user content",
"modifiers"
],
"min": 0,
"max": "*",
"base": {
"path": "BackboneElement.modifierExtension",
"min": 0,
"max": "*"
},
"type": [
{
"code": "Extension"
}
],
"constraint": [
{
"key": "ele-1",
"severity": "error",
"human": "All FHIR elements must have a @value or children",
"expression": "hasValue() or (children().count() > id.count())",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element"
},
{
"key": "ext-1",
"severity": "error",
"human": "Must have either extensions or value[x], not both",
"expression": "extension.exists() != value.exists()",
"xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
"source": "http://hl7.org/fhir/StructureDefinition/Extension"
}
],
"isModifier": true,
"isModifierReason": "Modifier extensions are expected to modify the meaning or interpretation of the element that contains them",
"isSummary": true,
"mapping": [
{
"identity": "rim",
"map": "N/A"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.MolekularesTumorboard.Datum",
"path": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.MolekularesTumorboard.Datum",
"short": "Datum",
"definition": "Datum des Tumorboards",
"min": 1,
"max": "1",
"base": {
"path": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.MolekularesTumorboard.Datum",
"min": 1,
"max": "1"
},
"type": [
{
"code": "date"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.MolekularesTumorboard.EmpfehlungStudie",
"path": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.MolekularesTumorboard.EmpfehlungStudie",
"short": "Empfehlung Studie",
"definition": "Empfehlung zur Studienteilnahme ja/nein",
"min": 0,
"max": "1",
"base": {
"path": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.MolekularesTumorboard.EmpfehlungStudie",
"min": 0,
"max": "1"
},
"type": [
{
"code": "code"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.MolekularesTumorboard.EmpfehlungBeratung",
"path": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.MolekularesTumorboard.EmpfehlungBeratung",
"short": "Empfehlung humangenetische Beratung",
"definition": "Empfehlung zu einer humangenetischen Beratung ja/nein",
"min": 0,
"max": "1",
"base": {
"path": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.MolekularesTumorboard.EmpfehlungBeratung",
"min": 0,
"max": "1"
},
"type": [
{
"code": "code"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.MolekularesTumorboard.EmpfehlungReevaluation",
"path": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.MolekularesTumorboard.EmpfehlungReevaluation",
"short": "Empfehlung Reevaluation",
"definition": "Empfehlung zur Reevaluation der molekularen Diagnostik ja/nein",
"min": 0,
"max": "1",
"base": {
"path": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.MolekularesTumorboard.EmpfehlungReevaluation",
"min": 0,
"max": "1"
},
"type": [
{
"code": "code"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.MolekularesTumorboard.EmpfehlungOperation",
"path": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.MolekularesTumorboard.EmpfehlungOperation",
"short": "Empfehlung Operation",
"definition": "Empfehlung zur Operation ja/nein",
"min": 0,
"max": "1",
"base": {
"path": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.MolekularesTumorboard.EmpfehlungOperation",
"min": 0,
"max": "1"
},
"type": [
{
"code": "code"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.MolekularesTumorboard.EmpfehlungOperationArt",
"path": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.MolekularesTumorboard.EmpfehlungOperationArt",
"short": "empfohlenene Operation",
"definition": "empfohlenen Operation",
"min": 0,
"max": "1",
"base": {
"path": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.MolekularesTumorboard.EmpfehlungOperationArt",
"min": 0,
"max": "1"
},
"type": [
{
"code": "code"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.MolekularesTumorboard.EmpfehlungOperationRisikoreduzierend",
"path": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.MolekularesTumorboard.EmpfehlungOperationRisikoreduzierend",
"short": "empfohlene Operation ist riskoreduzierend",
"definition": "empfohlenen Operation ist riskoreduzierend ja/nein",
"min": 0,
"max": "1",
"base": {
"path": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.MolekularesTumorboard.EmpfehlungOperationRisikoreduzierend",
"min": 0,
"max": "1"
},
"type": [
{
"code": "code"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.MolekularesTumorboard.EmpfehlungOperationTherapeutisch",
"path": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.MolekularesTumorboard.EmpfehlungOperationTherapeutisch",
"short": "empfohlene Operation ist therapeutisch",
"definition": "empfohlenene Operation ist therapeutisch ja/nein",
"min": 0,
"max": "1",
"base": {
"path": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.MolekularesTumorboard.EmpfehlungOperationTherapeutisch",
"min": 0,
"max": "1"
},
"type": [
{
"code": "code"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.MolekularesTumorboard.DurchgefuehrteOperation",
"path": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.MolekularesTumorboard.DurchgefuehrteOperation",
"short": "Durchgeführte Operation",
"definition": "Durchgeführte Operation nach OPS inkl. Version",
"min": 0,
"max": "*",
"base": {
"path": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.MolekularesTumorboard.DurchgefuehrteOperation",
"min": 0,
"max": "*"
},
"type": [
{
"code": "code"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.EmpfohleneStudie",
"path": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.EmpfohleneStudie",
"short": "Empfohlene Studieneinschlüsse",
"definition": "Empfohlene Studieneinschlüsse",
"min": 0,
"max": "*",
"base": {
"path": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.EmpfohleneStudie",
"min": 0,
"max": "*"
},
"type": [
{
"code": "BackboneElement"
}
],
"constraint": [
{
"key": "ele-1",
"severity": "error",
"human": "All FHIR elements must have a @value or children",
"expression": "hasValue() or (children().count() > id.count())",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.EmpfohleneStudie.id",
"path": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.EmpfohleneStudie.id",
"representation": [
"xmlAttr"
],
"short": "Unique id for inter-element referencing",
"definition": "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.",
"min": 0,
"max": "1",
"base": {
"path": "Element.id",
"min": 0,
"max": "1"
},
"type": [
{
"extension": [
{
"url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
"valueUrl": "string"
}
],
"code": "http://hl7.org/fhirpath/System.String"
}
],
"isModifier": false,
"isSummary": false,
"mapping": [
{
"identity": "rim",
"map": "n/a"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.EmpfohleneStudie.extension",
"path": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.EmpfohleneStudie.extension",
"slicing": {
"discriminator": [
{
"type": "value",
"path": "url"
}
],
"description": "Extensions are always sliced by (at least) url",
"rules": "open"
},
"short": "Additional content defined by implementations",
"definition": "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.",
"comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
"alias": [
"extensions",
"user content"
],
"min": 0,
"max": "*",
"base": {
"path": "Element.extension",
"min": 0,
"max": "*"
},
"type": [
{
"code": "Extension"
}
],
"constraint": [
{
"key": "ele-1",
"severity": "error",
"human": "All FHIR elements must have a @value or children",
"expression": "hasValue() or (children().count() > id.count())",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element"
},
{
"key": "ext-1",
"severity": "error",
"human": "Must have either extensions or value[x], not both",
"expression": "extension.exists() != value.exists()",
"xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
"source": "http://hl7.org/fhir/StructureDefinition/Extension"
}
],
"isModifier": false,
"isSummary": false,
"mapping": [
{
"identity": "rim",
"map": "n/a"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.EmpfohleneStudie.modifierExtension",
"path": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.EmpfohleneStudie.modifierExtension",
"short": "Extensions that cannot be ignored even if unrecognized",
"definition": "May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.\n\nModifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).",
"comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
"requirements": "Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](http://hl7.org/fhir/R4/extensibility.html#modifierExtension).",
"alias": [
"extensions",
"user content",
"modifiers"
],
"min": 0,
"max": "*",
"base": {
"path": "BackboneElement.modifierExtension",
"min": 0,
"max": "*"
},
"type": [
{
"code": "Extension"
}
],
"constraint": [
{
"key": "ele-1",
"severity": "error",
"human": "All FHIR elements must have a @value or children",
"expression": "hasValue() or (children().count() > id.count())",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element"
},
{
"key": "ext-1",
"severity": "error",
"human": "Must have either extensions or value[x], not both",
"expression": "extension.exists() != value.exists()",
"xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
"source": "http://hl7.org/fhir/StructureDefinition/Extension"
}
],
"isModifier": true,
"isModifierReason": "Modifier extensions are expected to modify the meaning or interpretation of the element that contains them",
"isSummary": true,
"mapping": [
{
"identity": "rim",
"map": "N/A"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.EmpfohleneStudie.Identifier",
"path": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.EmpfohleneStudie.Identifier",
"short": "Identifier",
"definition": "interner Identifikator der Studie",
"min": 0,
"max": "1",
"base": {
"path": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.EmpfohleneStudie.Identifier",
"min": 0,
"max": "1"
},
"type": [
{
"code": "string"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.EmpfohleneStudie.Register",
"path": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.EmpfohleneStudie.Register",
"short": "Register",
"definition": "Registersystematik, in dem die StudienID angegeben wird (NCT, EudraCT/CTIS, DRKS, andere, unbekannt)",
"min": 0,
"max": "1",
"base": {
"path": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.EmpfohleneStudie.Register",
"min": 0,
"max": "1"
},
"type": [
{
"code": "code"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.EmpfohleneStudie.StudienID",
"path": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.EmpfohleneStudie.StudienID",
"short": "Studie",
"definition": "StudienID in einer Registersystematik",
"min": 0,
"max": "1",
"base": {
"path": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.EmpfohleneStudie.StudienID",
"min": 0,
"max": "1"
},
"type": [
{
"code": "code"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.EmpfohleneStudie.Studienname",
"path": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.EmpfohleneStudie.Studienname",
"short": "Name der Studie",
"definition": "Name der Studie",
"min": 1,
"max": "1",
"base": {
"path": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.EmpfohleneStudie.Studienname",
"min": 1,
"max": "1"
},
"type": [
{
"code": "string"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.EmpfohleneStudie.Substanzen",
"path": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.EmpfohleneStudie.Substanzen",
"short": "Substanzen",
"definition": "Substanzen, die in der Studie eingesetzt werden, nach ATC kodiert",
"min": 0,
"max": "*",
"base": {
"path": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.EmpfohleneStudie.Substanzen",
"min": 0,
"max": "*"
},
"type": [
{
"code": "code"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.EmpfohleneStudie.Evidenzgrad",
"path": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.EmpfohleneStudie.Evidenzgrad",
"short": "Evidenzgrad",
"definition": "Evidenzgrad",
"min": 0,
"max": "1",
"base": {
"path": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.EmpfohleneStudie.Evidenzgrad",
"min": 0,
"max": "1"
},
"type": [
{
"code": "code"
}
]
},
{
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"max": "*",
"base": {
"path": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.EmpfohleneStudie.ZusatzverweiseEvidenzgraduierung",
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"type": [
{
"code": "string"
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]
},
{
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"definition": "Priorität der Studie, falls mehrere Studien empfohlen wurde. 1 ist höchste Priorität",
"min": 0,
"max": "1",
"base": {
"path": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.EmpfohleneStudie.Prioritaet",
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]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.EmpfohleneStudie.Variante",
"path": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.EmpfohleneStudie.Variante",
"short": "Variante",
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"min": 0,
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"base": {
"path": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.EmpfohleneStudie.Variante",
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"type": [
{
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]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.Therapieempfehlung",
"path": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.Therapieempfehlung",
"short": "String",
"definition": "String",
"min": 0,
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"base": {
"path": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.Therapieempfehlung",
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{
"code": "BackboneElement"
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],
"constraint": [
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}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.Therapieempfehlung.id",
"path": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.Therapieempfehlung.id",
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],
"short": "Unique id for inter-element referencing",
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],
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},
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"comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
"requirements": "Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](http://hl7.org/fhir/R4/extensibility.html#modifierExtension).",
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"key": "ext-1",
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{
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"path": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.Therapieempfehlung.Identifier",
"short": "Identifier",
"definition": "interner Identifikator der Therapieempfehlung",
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"max": "1",
"base": {
"path": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.Therapieempfehlung.Identifier",
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{
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"path": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.Therapieempfehlung.EmpfehlungTyp",
"short": "Typ der Empfehlung",
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"max": "1",
"base": {
"path": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.Therapieempfehlung.EmpfehlungTyp",
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"type": [
{
"code": "code"
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]
},
{
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"path": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.Therapieempfehlung.Substanz",
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"definition": "Substanzen, die empfohlen werden, nach ATC kodiert",
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"base": {
"path": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.Therapieempfehlung.Substanz",
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"code": "code"
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]
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"path": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.Therapieempfehlung.Evidenzgrad",
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"definition": "Evidenzgrad (m1A - m4, unbekannt)",
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"path": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.Therapieempfehlung.Evidenzgrad",
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"type": [
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},
{
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"path": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.Therapieempfehlung.Prioritaet",
"short": "Priorität",
"definition": "Priorität der Therapieempfehlung, falls mehrere Empfehlungen gegeben wurden. 1 ist höchste Priorität",
"min": 0,
"max": "1",
"base": {
"path": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.Therapieempfehlung.Prioritaet",
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},
"type": [
{
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]
},
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"short": "Variante",
"definition": "interne VariantenID der Variante, die für die Therapieempfehlung relevant ist",
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"max": "*",
"base": {
"path": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.Therapieempfehlung.Variante",
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"type": [
{
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]
},
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"path": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.Therapieempfehlung.TherapeutischeStrategie",
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"max": "1",
"base": {
"path": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.Therapieempfehlung.TherapeutischeStrategie",
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"code": "code"
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]
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"path": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.PraeventiveUntersuchungen",
"short": "Präventive Maßnahmen",
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"base": {
"path": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.PraeventiveUntersuchungen",
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],
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"path": "Element.id",
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"requirements": "Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](http://hl7.org/fhir/R4/extensibility.html#modifierExtension).",
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"type": [
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],
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"key": "ele-1",
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},
{
"key": "ext-1",
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{
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"path": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.PraeventiveUntersuchungen.Identifier",
"short": "Identifier",
"definition": "interner Identifikator der präventiven Maßnahme",
"min": 0,
"max": "1",
"base": {
"path": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.PraeventiveUntersuchungen.Identifier",
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},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.PraeventiveUntersuchungen.ArtUntersuchung",
"path": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.PraeventiveUntersuchungen.ArtUntersuchung",
"short": "Art der Untersuchung",
"definition": "Art der Untersuchung(z.B. Breast Imaging, MRI, MGR, US;Colonoscopy ; Esophago-gastro-duodenoscopy )",
"min": 0,
"max": "1",
"base": {
"path": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.PraeventiveUntersuchungen.ArtUntersuchung",
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"max": "1"
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"type": [
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"code": "string"
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]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFollowup",
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFollowup",
"short": "Follow-up und Umsetzung der Therapieempfehlung",
"definition": "Follow-up und Umsetzung der Therapieempfehlung",
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"max": "*",
"base": {
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFollowup",
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},
{
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],
"short": "Unique id for inter-element referencing",
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"max": "1",
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"path": "Element.id",
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},
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{
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{
"url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
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],
"code": "http://hl7.org/fhirpath/System.String"
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],
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},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFollowup.extension",
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},
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{
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"path": "mii-lm-mvgenomseq-onkologie.OnkologieFollowup.modifierExtension",
"short": "Extensions that cannot be ignored even if unrecognized",
"definition": "May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.\n\nModifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).",
"comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
"requirements": "Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](http://hl7.org/fhir/R4/extensibility.html#modifierExtension).",
"alias": [
"extensions",
"user content",
"modifiers"
],
"min": 0,
"max": "*",
"base": {
"path": "BackboneElement.modifierExtension",
"min": 0,
"max": "*"
},
"type": [
{
"code": "Extension"
}
],
"constraint": [
{
"key": "ele-1",
"severity": "error",
"human": "All FHIR elements must have a @value or children",
"expression": "hasValue() or (children().count() > id.count())",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element"
},
{
"key": "ext-1",
"severity": "error",
"human": "Must have either extensions or value[x], not both",
"expression": "extension.exists() != value.exists()",
"xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
"source": "http://hl7.org/fhir/StructureDefinition/Extension"
}
],
"isModifier": true,
"isModifierReason": "Modifier extensions are expected to modify the meaning or interpretation of the element that contains them",
"isSummary": true,
"mapping": [
{
"identity": "rim",
"map": "N/A"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFollowup.Datum",
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFollowup.Datum",
"short": "Datum",
"definition": "Datum des Follow-up",
"min": 1,
"max": "1",
"base": {
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFollowup.Datum",
"min": 1,
"max": "1"
},
"type": [
{
"code": "date"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFollowup.MetachroneTumore",
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFollowup.MetachroneTumore",
"short": "Auftreten Metachroner Tumore",
"definition": "Auftreten metachroner Tumore ja/nein",
"min": 0,
"max": "*",
"base": {
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFollowup.MetachroneTumore",
"min": 0,
"max": "*"
},
"type": [
{
"code": "code"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFollowup.MetachroneDiagnose",
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFollowup.MetachroneDiagnose",
"short": "Diagnose",
"definition": "Diagnose des metachronen Tumors laut ICD-10",
"min": 1,
"max": "1",
"base": {
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFollowup.MetachroneDiagnose",
"min": 1,
"max": "1"
},
"type": [
{
"code": "code"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFollowup.ECOG",
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFollowup.ECOG",
"short": "ECOG-Status",
"definition": "Eastern Cooperative Oncology Group (ECOG) Performance Status nach 0,1,2,3,4,5,unknown, not applicable",
"min": 0,
"max": "1",
"base": {
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFollowup.ECOG",
"min": 0,
"max": "1"
},
"type": [
{
"code": "code"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFollowup.Vitalstatus",
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFollowup.Vitalstatus",
"short": "Vitalstatus",
"definition": "Vitalstatus des Patienten zum Zeitpunkt des Follow-ups (lebend, verstorben, unbekannt)",
"min": 1,
"max": "1",
"base": {
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFollowup.Vitalstatus",
"min": 1,
"max": "1"
},
"type": [
{
"code": "code"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFollowup.LetzterKontakt",
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFollowup.LetzterKontakt",
"short": "Letzter Kontakt",
"definition": "Datum des letzten Kontakts",
"min": 0,
"max": "1",
"base": {
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFollowup.LetzterKontakt",
"min": 0,
"max": "1"
},
"type": [
{
"code": "date"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFollowup.Todesdatum",
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFollowup.Todesdatum",
"short": "Todesdatum",
"definition": "Datum des Todes",
"min": 0,
"max": "1",
"base": {
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFollowup.Todesdatum",
"min": 0,
"max": "1"
},
"type": [
{
"code": "date"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFollowup.Therapien",
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFollowup.Therapien",
"short": "Therapien",
"definition": "Therapien",
"min": 0,
"max": "*",
"base": {
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFollowup.Therapien",
"min": 0,
"max": "*"
},
"type": [
{
"code": "BackboneElement"
}
],
"constraint": [
{
"key": "ele-1",
"severity": "error",
"human": "All FHIR elements must have a @value or children",
"expression": "hasValue() or (children().count() > id.count())",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFollowup.Therapien.id",
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFollowup.Therapien.id",
"representation": [
"xmlAttr"
],
"short": "Unique id for inter-element referencing",
"definition": "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.",
"min": 0,
"max": "1",
"base": {
"path": "Element.id",
"min": 0,
"max": "1"
},
"type": [
{
"extension": [
{
"url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
"valueUrl": "string"
}
],
"code": "http://hl7.org/fhirpath/System.String"
}
],
"isModifier": false,
"isSummary": false,
"mapping": [
{
"identity": "rim",
"map": "n/a"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFollowup.Therapien.extension",
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFollowup.Therapien.extension",
"slicing": {
"discriminator": [
{
"type": "value",
"path": "url"
}
],
"description": "Extensions are always sliced by (at least) url",
"rules": "open"
},
"short": "Additional content defined by implementations",
"definition": "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.",
"comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
"alias": [
"extensions",
"user content"
],
"min": 0,
"max": "*",
"base": {
"path": "Element.extension",
"min": 0,
"max": "*"
},
"type": [
{
"code": "Extension"
}
],
"constraint": [
{
"key": "ele-1",
"severity": "error",
"human": "All FHIR elements must have a @value or children",
"expression": "hasValue() or (children().count() > id.count())",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element"
},
{
"key": "ext-1",
"severity": "error",
"human": "Must have either extensions or value[x], not both",
"expression": "extension.exists() != value.exists()",
"xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
"source": "http://hl7.org/fhir/StructureDefinition/Extension"
}
],
"isModifier": false,
"isSummary": false,
"mapping": [
{
"identity": "rim",
"map": "n/a"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFollowup.Therapien.modifierExtension",
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFollowup.Therapien.modifierExtension",
"short": "Extensions that cannot be ignored even if unrecognized",
"definition": "May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.\n\nModifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).",
"comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
"requirements": "Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](http://hl7.org/fhir/R4/extensibility.html#modifierExtension).",
"alias": [
"extensions",
"user content",
"modifiers"
],
"min": 0,
"max": "*",
"base": {
"path": "BackboneElement.modifierExtension",
"min": 0,
"max": "*"
},
"type": [
{
"code": "Extension"
}
],
"constraint": [
{
"key": "ele-1",
"severity": "error",
"human": "All FHIR elements must have a @value or children",
"expression": "hasValue() or (children().count() > id.count())",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element"
},
{
"key": "ext-1",
"severity": "error",
"human": "Must have either extensions or value[x], not both",
"expression": "extension.exists() != value.exists()",
"xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
"source": "http://hl7.org/fhir/StructureDefinition/Extension"
}
],
"isModifier": true,
"isModifierReason": "Modifier extensions are expected to modify the meaning or interpretation of the element that contains them",
"isSummary": true,
"mapping": [
{
"identity": "rim",
"map": "N/A"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFollowup.Therapien.reference",
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFollowup.Therapien.reference",
"short": "Referenz Studien-/ Therapieempfehlung",
"definition": "Referenz auf Studien- / Therapieempfehlung",
"min": 1,
"max": "1",
"base": {
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFollowup.Therapien.reference",
"min": 1,
"max": "1"
},
"type": [
{
"code": "string"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFollowup.Therapien.TherapieStart",
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFollowup.Therapien.TherapieStart",
"short": "Startdatum",
"definition": "Startdatum der Therapie",
"min": 0,
"max": "1",
"base": {
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFollowup.Therapien.TherapieStart",
"min": 0,
"max": "1"
},
"type": [
{
"code": "date"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFollowup.Therapien.TherapieEnde",
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFollowup.Therapien.TherapieEnde",
"short": "Enddatum",
"definition": "Enddatum der Therapie",
"min": 0,
"max": "1",
"base": {
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFollowup.Therapien.TherapieEnde",
"min": 0,
"max": "1"
},
"type": [
{
"code": "date"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFollowup.Therapien.TherapieWirkstoff",
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFollowup.Therapien.TherapieWirkstoff",
"short": "Wirkstoff",
"definition": "Wirkstoff der Therapie nach ATC oder Text bei nicht-ATC-Wirkstoffen",
"min": 0,
"max": "*",
"base": {
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFollowup.Therapien.TherapieWirkstoff",
"min": 0,
"max": "*"
},
"type": [
{
"code": "code"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFollowup.Therapien.TherapieAnsprechen",
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFollowup.Therapien.TherapieAnsprechen",
"short": "Ansprechen",
"definition": "Therapieansprechen der Therapie (PD: Progression, SD:Stabile Erkrankung, PR:Partielle Remission, CR:Komplette Remission)",
"min": 0,
"max": "1",
"base": {
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFollowup.Therapien.TherapieAnsprechen",
"min": 0,
"max": "1"
},
"type": [
{
"code": "code"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFollowup.Therapien.TherapieAnsprechenDatum",
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFollowup.Therapien.TherapieAnsprechenDatum",
"short": "Datum",
"definition": "Datum des Ansprechens der Vortherapie",
"min": 0,
"max": "1",
"base": {
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFollowup.Therapien.TherapieAnsprechenDatum",
"min": 0,
"max": "1"
},
"type": [
{
"code": "date"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFollowup.Therapien.TherapieEndeGrund",
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFollowup.Therapien.TherapieEndeGrund",
"short": "Ende der Therapie",
"definition": "Grund für das Ende der Vortherapie",
"min": 0,
"max": "1",
"base": {
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFollowup.Therapien.TherapieEndeGrund",
"min": 0,
"max": "1"
},
"type": [
{
"code": "code"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFollowup.Therapien.DatenquelleTherapieansprechen",
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFollowup.Therapien.DatenquelleTherapieansprechen",
"short": "Datenquelle Therapieansprechen",
"definition": "Datenquelle des Therapieansprechens (z.B. Arztbrief, Entlassungsbericht, Tumordokumentation)",
"min": 1,
"max": "1",
"base": {
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFollowup.Therapien.DatenquelleTherapieansprechen",
"min": 1,
"max": "1"
},
"type": [
{
"code": "string"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFollowup.PraeventiveMassnahmen",
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFollowup.PraeventiveMassnahmen",
"short": "Präventive Maßnahmen",
"definition": "Präventive Maßnahmen",
"min": 0,
"max": "*",
"base": {
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFollowup.PraeventiveMassnahmen",
"min": 0,
"max": "*"
},
"type": [
{
"code": "BackboneElement"
}
],
"constraint": [
{
"key": "ele-1",
"severity": "error",
"human": "All FHIR elements must have a @value or children",
"expression": "hasValue() or (children().count() > id.count())",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFollowup.PraeventiveMassnahmen.id",
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFollowup.PraeventiveMassnahmen.id",
"representation": [
"xmlAttr"
],
"short": "Unique id for inter-element referencing",
"definition": "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.",
"min": 0,
"max": "1",
"base": {
"path": "Element.id",
"min": 0,
"max": "1"
},
"type": [
{
"extension": [
{
"url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
"valueUrl": "string"
}
],
"code": "http://hl7.org/fhirpath/System.String"
}
],
"isModifier": false,
"isSummary": false,
"mapping": [
{
"identity": "rim",
"map": "n/a"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFollowup.PraeventiveMassnahmen.extension",
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFollowup.PraeventiveMassnahmen.extension",
"slicing": {
"discriminator": [
{
"type": "value",
"path": "url"
}
],
"description": "Extensions are always sliced by (at least) url",
"rules": "open"
},
"short": "Additional content defined by implementations",
"definition": "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.",
"comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
"alias": [
"extensions",
"user content"
],
"min": 0,
"max": "*",
"base": {
"path": "Element.extension",
"min": 0,
"max": "*"
},
"type": [
{
"code": "Extension"
}
],
"constraint": [
{
"key": "ele-1",
"severity": "error",
"human": "All FHIR elements must have a @value or children",
"expression": "hasValue() or (children().count() > id.count())",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element"
},
{
"key": "ext-1",
"severity": "error",
"human": "Must have either extensions or value[x], not both",
"expression": "extension.exists() != value.exists()",
"xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
"source": "http://hl7.org/fhir/StructureDefinition/Extension"
}
],
"isModifier": false,
"isSummary": false,
"mapping": [
{
"identity": "rim",
"map": "n/a"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFollowup.PraeventiveMassnahmen.modifierExtension",
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFollowup.PraeventiveMassnahmen.modifierExtension",
"short": "Extensions that cannot be ignored even if unrecognized",
"definition": "May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.\n\nModifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).",
"comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
"requirements": "Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](http://hl7.org/fhir/R4/extensibility.html#modifierExtension).",
"alias": [
"extensions",
"user content",
"modifiers"
],
"min": 0,
"max": "*",
"base": {
"path": "BackboneElement.modifierExtension",
"min": 0,
"max": "*"
},
"type": [
{
"code": "Extension"
}
],
"constraint": [
{
"key": "ele-1",
"severity": "error",
"human": "All FHIR elements must have a @value or children",
"expression": "hasValue() or (children().count() > id.count())",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element"
},
{
"key": "ext-1",
"severity": "error",
"human": "Must have either extensions or value[x], not both",
"expression": "extension.exists() != value.exists()",
"xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
"source": "http://hl7.org/fhir/StructureDefinition/Extension"
}
],
"isModifier": true,
"isModifierReason": "Modifier extensions are expected to modify the meaning or interpretation of the element that contains them",
"isSummary": true,
"mapping": [
{
"identity": "rim",
"map": "N/A"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFollowup.PraeventiveMassnahmen.reference",
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFollowup.PraeventiveMassnahmen.reference",
"short": "Referenz präventive Maßnahme",
"definition": "interne Referenz auf präventive Maßnahme",
"min": 1,
"max": "1",
"base": {
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFollowup.PraeventiveMassnahmen.reference",
"min": 1,
"max": "1"
},
"type": [
{
"code": "string"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFollowup.PraeventiveMassnahmen.preventiveMeasureResult",
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFollowup.PraeventiveMassnahmen.preventiveMeasureResult",
"short": "Ergebnis der präventiven Maßnahme",
"definition": "Ergebnis der präventiven Maßnahme (z.B. ohne Befund, benigner Befund, Malignom, unklar)",
"min": 1,
"max": "1",
"base": {
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFollowup.PraeventiveMassnahmen.preventiveMeasureResult",
"min": 1,
"max": "1"
},
"type": [
{
"code": "string"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFollowup.PraeventiveMassnahmen.preventiveMeasureDate",
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFollowup.PraeventiveMassnahmen.preventiveMeasureDate",
"short": "Datum der präventiven Maßnahme",
"definition": "Datum der präventiven Maßnahme",
"min": 0,
"max": "1",
"base": {
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFollowup.PraeventiveMassnahmen.preventiveMeasureDate",
"min": 0,
"max": "1"
},
"type": [
{
"code": "date"
}
]
}
]
},
"differential": {
"element": [
{
"id": "mii-lm-mvgenomseq-onkologie",
"path": "mii-lm-mvgenomseq-onkologie",
"short": "MII LM Modellvorhaben Genomsequenzierung Onkologie",
"definition": "MII LogicalModel Modellvorhaben Genomsequenzierung Onkologie"
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFall",
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall",
"short": "Onkologie-Fall",
"definition": "Onkologie-Fall",
"min": 0,
"max": "*",
"type": [
{
"code": "BackboneElement"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFall.Diagnose",
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.Diagnose",
"short": "Diagnose",
"definition": "Diagnose",
"min": 1,
"max": "1",
"type": [
{
"code": "BackboneElement"
}
],
"mapping": [
{
"identity": "MVGenomSeq-Datenkranz-to-MII-FHIR",
"map": "Condition"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFall.Diagnose.Haupttumordiagnose",
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.Diagnose.Haupttumordiagnose",
"short": "Haupttumordiagnose",
"definition": "Haupttumordiagnose in ICD-10-GM",
"min": 1,
"max": "1",
"type": [
{
"code": "code"
}
],
"mapping": [
{
"identity": "MVGenomSeq-Datenkranz-to-MII-FHIR",
"map": "Condition.code.coding.where(system='http://fhir.de/CodeSystem/bfarm/icd-10-gm').code"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFall.Diagnose.WeitereOnkologischeDiagnosen",
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.Diagnose.WeitereOnkologischeDiagnosen",
"short": "Weitere onkologische Diagnosen",
"definition": "Optional bei mehreren onkologischen Diagnosen, insbesondere Dokumentation als weiter onkologische Diagnose bei hereditären Tumordispositionssydroms (HT), bei HT zusätzliche Dokumentation ORPHAcode oder AlphaID, ein Code soweit vorhanden ist. Undiagnostizierte Erkrankungen sind mit ORPHA:616874 zu kodieren.",
"min": 0,
"max": "*",
"type": [
{
"code": "code"
}
],
"mapping": [
{
"identity": "MVGenomSeq-Datenkranz-to-MII-FHIR",
"map": "Condition.code.coding.where(system='http://fhir.de/CodeSystem/bfarm/icd-10-gm').code"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFall.Diagnose.Hauptdiagnosedatum",
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.Diagnose.Hauptdiagnosedatum",
"short": "Hauptdiagnosedatum",
"definition": "Datum der Erstdiagnose der Hauptdiagnose. Wenn Tag unbekannt -> 15. des Monats",
"min": 0,
"max": "1",
"type": [
{
"code": "date"
}
],
"mapping": [
{
"identity": "MVGenomSeq-Datenkranz-to-MII-FHIR",
"map": "Condition.extension.where(url='http://hl7.org/fhir/StructureDefinition/condition-assertedDate').valueDate"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFall.Diagnose.ECOGStatus",
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.Diagnose.ECOGStatus",
"short": "ECOG-Status",
"definition": "Eastern Cooperative Oncology Group (ECOG) Performance Status nach 0,1,2,3,4,5,unknown, not applicable",
"min": 0,
"max": "1",
"type": [
{
"code": "code"
}
],
"mapping": [
{
"identity": "MVGenomSeq-Datenkranz-to-MII-FHIR",
"map": "Observation.where(code='423740007' and system='http://snomed.info/sct').valueCodeableConcept.coding.code"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFall.Diagnose.KeimbahndiagnoseVorhanden",
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.Diagnose.KeimbahndiagnoseVorhanden",
"short": "Keimbahndiagnose vorhanden",
"definition": "Ja, Nein, unbekannt",
"min": 0,
"max": "1",
"type": [
{
"code": "code"
}
],
"mapping": [
{
"identity": "MVGenomSeq-Datenkranz-to-MII-FHIR",
"map": "no direct match, vsl. über FHIRPath automatisch generieren, wenn Keimbahndiagnose.exists()"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFall.Diagnose.Keimbahndiagnose",
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.Diagnose.Keimbahndiagnose",
"short": "Keimbahndiagnose",
"definition": "Keimbahndiagnosen nach ICD-10-GM.Bei Diagnose eines hereditären Tumordispositionssydroms als Teil der OE ist verpflichtend anzugeben mit ICD10 und ORPHA oder AlphaID ",
"min": 0,
"max": "*",
"type": [
{
"code": "code"
}
],
"mapping": [
{
"identity": "MVGenomSeq-Datenkranz-to-MII-FHIR",
"map": "no direct match. Keimbahndiagnose existiert als Konzept nicht, hier könnte / müsste mit Condition.category gearbeitet werden, z.B. SNOMED Hereditary cancer-predisposing syndrome (disorder)"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFall.Diagnose.HPOPhaenotypisierung",
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.Diagnose.HPOPhaenotypisierung",
"short": "Phänotypisierung nach HPO ",
"definition": "Human Phenotype Ontology.Bei Diagnose eines hereditären Tumordispositionssydroms als Teil der OE, wenn vorhanden angeben (optional) ",
"min": 0,
"max": "*",
"type": [
{
"code": "code"
}
],
"mapping": [
{
"identity": "MVGenomSeq-Datenkranz-to-MII-FHIR",
"map": "Observation.where(valueCodeableConcept.coding.system='http://human-phenotype-ontology.org')"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFall.Diagnose.Histologie",
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.Diagnose.Histologie",
"short": "Histologie nach ICD-O-3",
"definition": "Histologische Morphologie und Verhalten nach ICD-O-3",
"min": 1,
"max": "1",
"type": [
{
"code": "code"
}
],
"mapping": [
{
"identity": "MVGenomSeq-Datenkranz-to-MII-FHIR",
"map": "Condition.extension.where(url='https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-ex-onko-histology-morphology-behavior-icdo3').valueCodeableConcept.coding.code"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFall.Diagnose.Topographie",
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.Diagnose.Topographie",
"short": "Topographie nach ICD-O-3",
"definition": "Topographie des Tumors nach ICD-O-3",
"min": 1,
"max": "1",
"type": [
{
"code": "code"
}
],
"mapping": [
{
"identity": "MVGenomSeq-Datenkranz-to-MII-FHIR",
"map": "Condition.bodySite.coding.code"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFall.Diagnose.Grading",
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.Diagnose.Grading",
"short": "Differenzierungsgrad",
"definition": "Gibt den Differenzierungsgrad des Tumors entsprechend der aktuellen TNM-Auflage an, Bei der Klassifikation sind die einschlägigen Regeln der Literatur (TNM) zu beachten.",
"min": 0,
"max": "1",
"type": [
{
"code": "code"
}
],
"mapping": [
{
"identity": "MVGenomSeq-Datenkranz-to-MII-FHIR",
"map": "Observation.where(code.coding.code='33732-9' and code.coding.system='http://loinc.org').valueCodeableConcept.coding.code"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFall.Diagnose.TNMSchluessel",
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.Diagnose.TNMSchluessel",
"short": "TNM-Klassifikation",
"definition": "TNM-Klassifikation des Tumors",
"min": 0,
"max": "1",
"type": [
{
"code": "string"
}
],
"mapping": [
{
"identity": "MVGenomSeq-Datenkranz-to-MII-FHIR",
"map": "Observation.where(code.coding.code='33732-9' and code.coding.system='http://snomed.info/sct').valueCodeableConcept.coding.code"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFall.Diagnose.TNMSystematik",
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.Diagnose.TNMSystematik",
"short": "TNM-Systematik",
"definition": "TNM-Systematik nach AJCC oder UICC",
"min": 0,
"max": "1",
"type": [
{
"code": "code"
}
],
"mapping": [
{
"identity": "MVGenomSeq-Datenkranz-to-MII-FHIR",
"map": "Laut Krebsregisterdaten nur UICC vorgesehen? kein expiziter Datenpunkt außer Version"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFall.Diagnose.WeitereKlassifikationen",
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.Diagnose.WeitereKlassifikationen",
"short": "Weitere Klassifikationen",
"definition": "Weitere Klassifikationen des Tumors zum Diagnosezeitpunkt",
"min": 0,
"max": "*",
"type": [
{
"code": "string"
}
],
"mapping": [
{
"identity": "MVGenomSeq-Datenkranz-to-MII-FHIR",
"map": "no direkt match - Observation - Nutzung des Profils WeitereKlassifikationen, aber aufgrund der Vielfalt der Klassifikationen keine direkte Zuordnung möglich"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFall.Diagnose.DiagnostischeVoruntersuchungen",
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.Diagnose.DiagnostischeVoruntersuchungen",
"short": "Diagnostische Voruntersuchungen",
"definition": "Diagnostische Voruntersuchungen zum Diagnosezeitpunkt. Bewertung der durchgeführten genetischen Diagnostik, nur für heriditäre Prädispositionssyndrome/ Erbliche Tumore",
"min": 0,
"max": "*",
"type": [
{
"code": "code"
}
],
"mapping": [
{
"identity": "MVGenomSeq-Datenkranz-to-MII-FHIR",
"map": "no direkt match"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFall.Vordiagnostik",
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.Vordiagnostik",
"short": "Vordiagnostik",
"definition": "Vordiagnostik",
"min": 0,
"max": "*",
"type": [
{
"code": "BackboneElement"
}
],
"mapping": [
{
"identity": "MVGenomSeq-Datenkranz-to-MII-FHIR",
"map": "Vordiagnostik"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFall.Vordiagnostik.ArtDiagnostik",
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.Vordiagnostik.ArtDiagnostik",
"short": "Diagnostik",
"definition": "Diagnostik, die vor dem MV Genomseq, durchgeführt wurde (Vorbefunde)",
"min": 1,
"max": "1",
"type": [
{
"code": "code"
}
],
"mapping": [
{
"identity": "MVGenomSeq-Datenkranz-to-MII-FHIR",
"map": "Diagnoste)"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFall.Vordiagnostik.DatumDiagnostik",
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.Vordiagnostik.DatumDiagnostik",
"short": "Datum",
"definition": "Datum der Diagnostik",
"min": 0,
"max": "1",
"type": [
{
"code": "date"
}
],
"mapping": [
{
"identity": "MVGenomSeq-Datenkranz-to-MII-FHIR",
"map": "Datum Diagnostik"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFall.MolekulareVorbefunde",
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.MolekulareVorbefunde",
"short": "klinisch relevante Ergebnisse der Diagnostik",
"definition": "klinisch relevante Ergebnisse der Diagnostik",
"min": 0,
"max": "*",
"type": [
{
"code": "BackboneElement"
}
],
"mapping": [
{
"identity": "MVGenomSeq-Datenkranz-to-MII-FHIR",
"map": "klinisch relevante Ergebnisse der Diagnostik"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFall.MolekulareVorbefunde.Gen",
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.MolekulareVorbefunde.Gen",
"short": "Gen",
"definition": "Gen kodiert nach HGNC",
"min": 1,
"max": "1",
"type": [
{
"code": "code"
}
],
"mapping": [
{
"identity": "MVGenomSeq-Datenkranz-to-MII-FHIR",
"map": "Genert nach HGNC"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFall.MolekulareVorbefunde.Transkript",
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.MolekulareVorbefunde.Transkript",
"short": "Transkript",
"definition": "Transkript kodiert nach Ensembl/RefSeq",
"min": 0,
"max": "1",
"type": [
{
"code": "code"
}
],
"mapping": [
{
"identity": "MVGenomSeq-Datenkranz-to-MII-FHIR",
"map": "Transkriranskript kodiert nach Ensembl/RefSeq"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFall.MolekulareVorbefunde.DNAChange",
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.MolekulareVorbefunde.DNAChange",
"short": "DNA-Veränderung",
"definition": "DNA-Verändung nach cHGVS",
"min": 0,
"max": "1",
"type": [
{
"code": "code"
}
],
"mapping": [
{
"identity": "MVGenomSeq-Datenkranz-to-MII-FHIR",
"map": "DNA-VeränVerändung nach cHGVS"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFall.MolekulareVorbefunde.ProteinChange",
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.MolekulareVorbefunde.ProteinChange",
"short": "Protein-Veränderung",
"definition": "Protein-Veränderung nach pHGVS",
"min": 0,
"max": "1",
"type": [
{
"code": "code"
}
],
"mapping": [
{
"identity": "MVGenomSeq-Datenkranz-to-MII-FHIR",
"map": "Protein-Verändotein-Veränderung nach pHGVS"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFall.MolekulareVorbefunde.TypAlteration",
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.MolekulareVorbefunde.TypAlteration",
"short": "Typ der Alteration",
"definition": "Typ der Alteration / Variantenklasse nach Sequence ontology (SO)",
"min": 0,
"max": "1",
"type": [
{
"code": "code"
}
],
"mapping": [
{
"identity": "MVGenomSeq-Datenkranz-to-MII-FHIR",
"map": "Typ der Alteratr Alteration / Variantenklasse nach Sequence ontology (SO)"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFall.MolekulareVorbefunde.KomplexeAlteration",
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.MolekulareVorbefunde.KomplexeAlteration",
"short": "Komplexe Alteration",
"definition": "Ausführliche Beschreibung bei komplexen Alteration z.B. Fusion",
"min": 0,
"max": "1",
"type": [
{
"code": "string"
}
],
"mapping": [
{
"identity": "MVGenomSeq-Datenkranz-to-MII-FHIR",
"map": "Komplexe AlteratAusführliche Beschreibung"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFall.SystemischeVortherapien",
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.SystemischeVortherapien",
"short": "Systemische Vortherapien",
"definition": "Systemische Vortherapien",
"min": 0,
"max": "*",
"type": [
{
"code": "BackboneElement"
}
],
"mapping": [
{
"identity": "MVGenomSeq-Datenkranz-to-MII-FHIR",
"map": "Procedure"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFall.SystemischeVortherapien.ArtTherapie",
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.SystemischeVortherapien.ArtTherapie",
"short": "Bezug zur operativen Therapie",
"definition": "Bezug der Vortherapie zu einer operativen Therapie, z.B. adjuvant, neoadjuvant",
"min": 1,
"max": "1",
"type": [
{
"code": "code"
}
],
"mapping": [
{
"identity": "MVGenomSeq-Datenkranz-to-MII-FHIR",
"map": "Procedure.extension.where(url='StellungZurOp')"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFall.SystemischeVortherapien.IntentionTherapie",
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.SystemischeVortherapien.IntentionTherapie",
"short": "Intention",
"definition": "Intention der Vortherapie, z.B. kurativ, palliativ",
"min": 0,
"max": "1",
"type": [
{
"code": "code"
}
],
"mapping": [
{
"identity": "MVGenomSeq-Datenkranz-to-MII-FHIR",
"map": "Procedure.extension.where(url='Intention')"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFall.SystemischeVortherapien.Substanz",
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.SystemischeVortherapien.Substanz",
"short": "Substanz",
"definition": "Substanz der Vortherapie nach ATC oder Text bei nicht-ATC-Wirkstoffen",
"min": 0,
"max": "*",
"type": [
{
"code": "code"
}
],
"mapping": [
{
"identity": "MVGenomSeq-Datenkranz-to-MII-FHIR",
"map": "MedicationStatement.medicationCode.coding[atc-de].code"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFall.SystemischeVortherapien.Therapiestart",
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.SystemischeVortherapien.Therapiestart",
"short": "Startdatum",
"definition": "Startdatum der Vortherapie. Wenn Datum unbekannt, dann 15. des Monats",
"min": 0,
"max": "1",
"type": [
{
"code": "date"
}
],
"mapping": [
{
"identity": "MVGenomSeq-Datenkranz-to-MII-FHIR",
"map": "Procedure.effectivePeriod.start"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFall.SystemischeVortherapien.Therapieende",
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.SystemischeVortherapien.Therapieende",
"short": "Enddatum",
"definition": "Enddatum der Vortherapie. Wenn Datum unbekannt, dann 15. des Monats",
"min": 0,
"max": "1",
"type": [
{
"code": "date"
}
],
"mapping": [
{
"identity": "MVGenomSeq-Datenkranz-to-MII-FHIR",
"map": "Procedure.effectivePeriod.end"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFall.SystemischeVortherapien.EndeGrund",
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.SystemischeVortherapien.EndeGrund",
"short": "Ende der Therapie",
"definition": "Grund für das Ende der Vortherapie",
"min": 0,
"max": "1",
"type": [
{
"code": "code"
}
],
"mapping": [
{
"identity": "MVGenomSeq-Datenkranz-to-MII-FHIR",
"map": "Procedure.outcome"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFall.SystemischeVortherapien.TherapieAnsprechen",
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.SystemischeVortherapien.TherapieAnsprechen",
"short": "Ansprechen",
"definition": "Therapieansprechen der fallrelevante, systemische Vortherapie (PD: Progression, SD:Stabile Erkrankung, PR:Partielle Remission, CR:Komplette Remission)",
"min": 0,
"max": "1",
"type": [
{
"code": "code"
}
],
"mapping": [
{
"identity": "MVGenomSeq-Datenkranz-to-MII-FHIR",
"map": "Verlauf.valueCodeableConcept.coding.code"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFall.SystemischeVortherapien.TherapieAnsprechenDatum",
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.SystemischeVortherapien.TherapieAnsprechenDatum",
"short": "Datum",
"definition": "Datum des Ansprechens der Vortherapie",
"min": 0,
"max": "1",
"type": [
{
"code": "date"
}
],
"mapping": [
{
"identity": "MVGenomSeq-Datenkranz-to-MII-FHIR",
"map": "Verlauf.effectiveDateTime"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular",
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular",
"short": "Molekulare Diagnostik",
"definition": "Molekulare Diagnostik",
"min": 0,
"max": "*",
"type": [
{
"code": "BackboneElement"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.EinfacheVariante",
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.EinfacheVariante",
"short": "Einfache Variante inkl. Fusionen im codierenden Bereich",
"definition": "Einfache Variante inkl. Fusionen im codierenden Bereich",
"min": 0,
"max": "*",
"type": [
{
"code": "BackboneElement"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.EinfacheVariante.Identifier",
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.EinfacheVariante.Identifier",
"short": "Identifier",
"definition": "interner Identifikator der Variante",
"min": 0,
"max": "1",
"type": [
{
"code": "string"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.EinfacheVariante.Gen",
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.EinfacheVariante.Gen",
"short": "Gen",
"definition": "Gen kodiert nach HGNC",
"min": 1,
"max": "1",
"type": [
{
"code": "code"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.EinfacheVariante.Transkript",
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.EinfacheVariante.Transkript",
"short": "Transkript",
"definition": "Transkript kodiert nach Ensembl/RefSeq",
"min": 0,
"max": "1",
"type": [
{
"code": "code"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.EinfacheVariante.DNAChange",
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.EinfacheVariante.DNAChange",
"short": "DNA-Veränderung",
"definition": "DNA-Verändung nach cHGVS",
"min": 0,
"max": "1",
"type": [
{
"code": "code"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.EinfacheVariante.ProteinChange",
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.EinfacheVariante.ProteinChange",
"short": "Protein-Veränderung",
"definition": "Protein-Veränderung nach pHGVS",
"min": 0,
"max": "1",
"type": [
{
"code": "code"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.EinfacheVariante.TypAlteration",
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.EinfacheVariante.TypAlteration",
"short": "Typ der Alteration",
"definition": "Typ der Alteration / Variantenklasse nach Sequence ontology (SO)",
"min": 0,
"max": "1",
"type": [
{
"code": "code"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.EinfacheVariante.Lokalization",
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.EinfacheVariante.Lokalization",
"short": "Lokalisation der Variante",
"definition": "Lokalisation im kodierenden, regulatorischen oder intergenischen Bereich",
"min": 0,
"max": "1",
"type": [
{
"code": "code"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.EinfacheVariante.LossOfHeterozygosity",
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.EinfacheVariante.LossOfHeterozygosity",
"short": "Loss of Heterozygosity (LOH)",
"definition": "Loss of Heterozygosity (LOH) im Bereich der Variante Ja / Nein",
"min": 0,
"max": "1",
"type": [
{
"code": "code"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.CopyNumberVariante",
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.CopyNumberVariante",
"short": "Variante mit Kopienzahlveränderung (Copy Number Variation, CNV)",
"definition": "Variante mit Kopienzahlveränderung (Copy Number Variation, CNV)",
"min": 0,
"max": "*",
"type": [
{
"code": "BackboneElement"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.CopyNumberVariante.Identifier",
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.CopyNumberVariante.Identifier",
"short": "Identifier",
"definition": "interner Identifikator der Variante",
"min": 0,
"max": "1",
"type": [
{
"code": "string"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.CopyNumberVariante.CNVTyp",
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.CopyNumberVariante.CNVTyp",
"short": "CNV-Typ",
"definition": "Komplettverlust, partieller Verlust, Amplifikation",
"min": 0,
"max": "*",
"type": [
{
"code": "BackboneElement"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.CopyNumberVariante.Quellprobe",
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.CopyNumberVariante.Quellprobe",
"short": "Art der Quellprobe",
"definition": "Art der Quellprobe (somatisch oder Keimbahn)",
"min": 0,
"max": "1",
"type": [
{
"code": "code"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.CopyNumberVariante.Gen",
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.CopyNumberVariante.Gen",
"short": "Gen",
"definition": "Gen kodiert nach HGNC - falls nur ein Gen betreffend",
"min": 0,
"max": "1",
"type": [
{
"code": "code"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.CopyNumberVariante.Chromosom",
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.CopyNumberVariante.Chromosom",
"short": "Chromosom",
"definition": "Chromosom",
"min": 0,
"max": "1",
"type": [
{
"code": "code"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.CopyNumberVariante.CNVStartPosition",
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.CopyNumberVariante.CNVStartPosition",
"short": "CNV-Start",
"definition": "Startposition des CNV basierend auf Hg38",
"min": 0,
"max": "1",
"type": [
{
"code": "integer"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.CopyNumberVariante.CNVEndPosition",
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.CopyNumberVariante.CNVEndPosition",
"short": "CNV-Ende",
"definition": "Endposition des CNV basierend auf Hg38",
"min": 0,
"max": "1",
"type": [
{
"code": "integer"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.CopyNumberVariante.CopyNumber",
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.CopyNumberVariante.CopyNumber",
"short": "Copy Number",
"definition": "Copy Number",
"min": 0,
"max": "1",
"type": [
{
"code": "integer"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.CopyNumberVariante.Lokalization",
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.CopyNumberVariante.Lokalization",
"short": "Lokalisation der Variante",
"definition": "Lokalisation im kodierenden, regulatorischen oder intergenischen Bereich",
"min": 0,
"max": "1",
"type": [
{
"code": "code"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.StrukturelleVariante",
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.StrukturelleVariante",
"short": "Strukturelle Variante",
"definition": "Strukturelle Variante",
"min": 0,
"max": "*",
"type": [
{
"code": "BackboneElement"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.StrukturelleVariante.Identifier",
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.StrukturelleVariante.Identifier",
"short": "Identifier",
"definition": "interner Identifikator der Variante",
"min": 0,
"max": "1",
"type": [
{
"code": "string"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.StrukturelleVariante.Quellprobe",
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.StrukturelleVariante.Quellprobe",
"short": "Art der Quellprobe",
"definition": "Art der Quellprobe (somatisch oder Keimbahn)",
"min": 0,
"max": "1",
"type": [
{
"code": "code"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.StrukturelleVariante.Gen",
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.StrukturelleVariante.Gen",
"short": "Gen",
"definition": "N-terminales Gen",
"min": 0,
"max": "1",
"type": [
{
"code": "code"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.StrukturelleVariante.GenC",
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.StrukturelleVariante.GenC",
"short": "Gen",
"definition": "C-terminales Gen, falls in-frame und kodierend",
"min": 0,
"max": "1",
"type": [
{
"code": "code"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.StrukturelleVariante.StrukturTyp",
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.StrukturelleVariante.StrukturTyp",
"short": "Variantentyp",
"definition": "Variantentyp (Inversion, Translokation, Deletion, Insertion, Duplikation)",
"min": 0,
"max": "1",
"type": [
{
"code": "code"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.StrukturelleVariante.Beschreibung",
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.StrukturelleVariante.Beschreibung",
"short": "Beschreibung der Variante",
"definition": "Beschreibung der Variante nach HGVS oder ISCN",
"min": 0,
"max": "1",
"type": [
{
"code": "code"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.StrukturelleVariante.Nachweismethode",
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.StrukturelleVariante.Nachweismethode",
"short": "Nachweismethode",
"definition": "Nachweismethode (DNA / RNA)",
"min": 0,
"max": "1",
"type": [
{
"code": "code"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.StrukturelleVariante.Lokalization",
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.StrukturelleVariante.Lokalization",
"short": "Lokalisation der Variante",
"definition": "Lokalisation im kodierenden, regulatorischen oder intergenischen Bereich",
"min": 0,
"max": "1",
"type": [
{
"code": "code"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.ExpressionsVariante",
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.ExpressionsVariante",
"short": "Expressionsvariante",
"definition": "Expressionsvariante",
"min": 0,
"max": "*",
"type": [
{
"code": "BackboneElement"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.ExpressionsVariante.Identifier",
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.ExpressionsVariante.Identifier",
"short": "Identifier",
"definition": "interner Identifikator der Variante",
"min": 0,
"max": "1",
"type": [
{
"code": "string"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.ExpressionsVariante.Gen",
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.ExpressionsVariante.Gen",
"short": "Gen",
"definition": "Gen kodiert nach HGNC",
"min": 1,
"max": "1",
"type": [
{
"code": "code"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.ExpressionsVariante.Expression",
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.ExpressionsVariante.Expression",
"short": "Expression",
"definition": "Expression des Gens (über- oder unterexprimiert)",
"min": 0,
"max": "1",
"type": [
{
"code": "code"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.ExpressionsVariante.Bewertungsgrundlage",
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.ExpressionsVariante.Bewertungsgrundlage",
"short": "Bewertungsgrundlage",
"definition": "Bewertungsgrundlage der Expression (z.B. Vergleichskohorte von 400 Patienten)",
"min": 0,
"max": "1",
"type": [
{
"code": "string"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.ExpressionsVariante.TMB",
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.ExpressionsVariante.TMB",
"short": "Tumor Mutational Burden (TMB)",
"definition": "Tumor Mutational Burden (TMB) in Mut/Mb",
"min": 0,
"max": "1",
"type": [
{
"code": "decimal"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.ExpressionsVariante.HRD",
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.ExpressionsVariante.HRD",
"short": "Homologous Recombination Deficiency (HRD)",
"definition": "Homologous Recombination Deficiency (HRD) erhöht ja/nein",
"min": 0,
"max": "1",
"type": [
{
"code": "code"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.ExpressionsVariante.LST",
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.ExpressionsVariante.LST",
"short": "Large Scale Transition (LST)",
"definition": "Large Scale Transition (LST) erhöht ja/nein",
"min": 0,
"max": "1",
"type": [
{
"code": "code"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.ExpressionsVariante.TAI",
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.ExpressionsVariante.TAI",
"short": "Telomeric Allelic Imbalance (TAI)",
"definition": "Telomeric Allelic Imbalance (TAI) erhöht ja/nein",
"min": 0,
"max": "1",
"type": [
{
"code": "code"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.ExpressionsVariante.SBS",
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.ExpressionsVariante.SBS",
"short": "Single Base Substitution (SBS)",
"definition": "Single Base Substitution (SBS) erhöht ja/nein",
"min": 0,
"max": "1",
"type": [
{
"code": "code"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.ExpressionsVariante.SBSSignature",
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.ExpressionsVariante.SBSSignature",
"short": "Single Base Substitution Signature",
"definition": "Single Base Substitution Signature",
"min": 0,
"max": "1",
"type": [
{
"code": "code"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.ExpressionsVariante.Lokalization",
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.ExpressionsVariante.Lokalization",
"short": "Lokalisation der Variante",
"definition": "Lokalisation im kodierenden, regulatorischen oder intergenischen Bereich",
"min": 0,
"max": "1",
"type": [
{
"code": "code"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologiePlan",
"path": "mii-lm-mvgenomseq-onkologie.OnkologiePlan",
"short": "Therapieplan",
"definition": "Therapieplan",
"min": 0,
"max": "*",
"type": [
{
"code": "BackboneElement"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.MolekularesTumorboard",
"path": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.MolekularesTumorboard",
"short": "Molekulares Tumorboard",
"definition": "Molekulares Tumorboard",
"min": 0,
"max": "*",
"type": [
{
"code": "BackboneElement"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.MolekularesTumorboard.Datum",
"path": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.MolekularesTumorboard.Datum",
"short": "Datum",
"definition": "Datum des Tumorboards",
"min": 1,
"max": "1",
"type": [
{
"code": "date"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.MolekularesTumorboard.EmpfehlungStudie",
"path": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.MolekularesTumorboard.EmpfehlungStudie",
"short": "Empfehlung Studie",
"definition": "Empfehlung zur Studienteilnahme ja/nein",
"min": 0,
"max": "1",
"type": [
{
"code": "code"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.MolekularesTumorboard.EmpfehlungBeratung",
"path": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.MolekularesTumorboard.EmpfehlungBeratung",
"short": "Empfehlung humangenetische Beratung",
"definition": "Empfehlung zu einer humangenetischen Beratung ja/nein",
"min": 0,
"max": "1",
"type": [
{
"code": "code"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.MolekularesTumorboard.EmpfehlungReevaluation",
"path": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.MolekularesTumorboard.EmpfehlungReevaluation",
"short": "Empfehlung Reevaluation",
"definition": "Empfehlung zur Reevaluation der molekularen Diagnostik ja/nein",
"min": 0,
"max": "1",
"type": [
{
"code": "code"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.MolekularesTumorboard.EmpfehlungOperation",
"path": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.MolekularesTumorboard.EmpfehlungOperation",
"short": "Empfehlung Operation",
"definition": "Empfehlung zur Operation ja/nein",
"min": 0,
"max": "1",
"type": [
{
"code": "code"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.MolekularesTumorboard.EmpfehlungOperationArt",
"path": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.MolekularesTumorboard.EmpfehlungOperationArt",
"short": "empfohlenene Operation",
"definition": "empfohlenen Operation",
"min": 0,
"max": "1",
"type": [
{
"code": "code"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.MolekularesTumorboard.EmpfehlungOperationRisikoreduzierend",
"path": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.MolekularesTumorboard.EmpfehlungOperationRisikoreduzierend",
"short": "empfohlene Operation ist riskoreduzierend",
"definition": "empfohlenen Operation ist riskoreduzierend ja/nein",
"min": 0,
"max": "1",
"type": [
{
"code": "code"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.MolekularesTumorboard.EmpfehlungOperationTherapeutisch",
"path": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.MolekularesTumorboard.EmpfehlungOperationTherapeutisch",
"short": "empfohlene Operation ist therapeutisch",
"definition": "empfohlenene Operation ist therapeutisch ja/nein",
"min": 0,
"max": "1",
"type": [
{
"code": "code"
}
]
},
{
"id": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.MolekularesTumorboard.DurchgefuehrteOperation",
"path": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.MolekularesTumorboard.DurchgefuehrteOperation",
"short": "Durchgeführte Operation",
"definition": "Durchgeführte Operation nach OPS inkl. Version",
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"definition": "Typ der Empfehlung (z.B. inlabel, offlabel, compassionate use, unknown, secondary preventive)",
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}