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Source1

{
  "resourceType": "MedicationStatement",
  "id": "mii-exa-onko-modification-oxaliplatin-phase1",
  "meta": {
    "profile": [
      "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-systemische-therapie-medikation"
    ]
  },
  "medicationCodeableConcept": {
    "coding": [
      {
        "system": "http://fhir.de/CodeSystem/bfarm/atc",
        "code": "L01XA03",
        "display": "Oxaliplatin"
      }
    ],
    "text": "Oxaliplatin"
  },
  "status": "stopped",
  "statusReason": [
    {
      "coding": [
        {
          "code": "281647001",
          "system": "http://snomed.info/sct",
          "display": "Adverse reaction (disorder)"
        }
      ],
      "text": "Grade 3 peripheral neuropathy (CTCAE) - cumulative neurotoxicity from oxaliplatin"
    }
  ],
  "subject": {
    "reference": "Patient/example-modification"
  },
  "partOf": [
    {
      "reference": "Procedure/mii-exa-onko-folfox-phase1"
    }
  ],
  "basedOn": [
    {
      "reference": "CarePlan/mii-exa-onko-tumorkonferenz-folfox-modification"
    }
  ],
  "effectivePeriod": {
    "start": "2024-03-15",
    "end": "2024-06-10"
  },
  "note": [
    {
      "text": "FOLFOX4 - Cycles 1-6 only. Discontinued due to severe peripheral neuropathy. Patient experienced numbness and tingling in hands and feet (grade 3 CTCAE), interfering with daily activities."
    }
  ]
}