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Source1

{
  "resourceType": "ValueSet",
  "id": "mii-vs-mtb-immunohistochemistry-specific-codes",
  "language": "de-DE",
  "text": {
    "status": "generated",
    "div": "<!-- snip (see above) -->"
  },
  "url": "https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/ValueSet/mii-vs-mtb-immunohistochemistry-specific-codes",
  "version": "2027.0.0-ballot.1",
  "name": "MII_VS_MTB_Immunhistochemistry_Specific_Codes",
  "title": "MII VS MTB Immunhistochemistry Specific Codes",
  "status": "active",
  "experimental": false,
  "date": "2026-09-15T17:39:31+00:00",
  "publisher": "Medizininformatik-Initiative",
  "contact": [
    {
      "name": "Medizininformatik-Initiative",
      "telecom": [
        {
          "system": "url",
          "value": "https://www.medizininformatik-initiative.de"
        }
      ]
    }
  ],
  "description": "Spezifische LOINC und SNOMED Codes für immunhistochemische Untersuchungen. Diese Codes werden für das Slice 'spezifisch' im Immunohistochemistry Profil verwendet.",
  "jurisdiction": [
    {
      "coding": [
        {
          "system": "urn:iso:std:iso:3166",
          "code": "DE",
          "display": "Germany"
        }
      ]
    }
  ],
  "compose": {
    "include": [
      {
        "system": "http://snomed.info/sct",
        "filter": [
          {
            "property": "concept",
            "op": "descendent-of",
            "value": "1234806008"
          }
        ]
      },
      {
        "system": "http://loinc.org",
        "concept": [
          {
            "code": "55229-9",
            "display": "Immune stain study"
          },
          {
            "code": "18474-7",
            "display": "HER2 Ag [Presence] in Tissue by Immune stain"
          },
          {
            "code": "48676-1",
            "display": "HER2 Ag [Interpretation] in Tissue"
          },
          {
            "code": "85319-2",
            "display": "HER2 [Presence] in Breast cancer specimen by Immune stain"
          },
          {
            "code": "14228-1",
            "display": "Cells.estrogen receptor/cells in Tissue by Immune stain"
          },
          {
            "code": "14230-7",
            "display": "Cells.progesterone receptor/cells in Tissue by Immune stain"
          },
          {
            "code": "29593-1",
            "display": "Cells.Ki-67 nuclear Ag/cells in Tissue by Immune stain"
          },
          {
            "code": "33055-5",
            "display": "Ki-67 nuclear Ag [Presence] in Tissue by Immune stain"
          },
          {
            "code": "85330-9",
            "display": "Cells.Ki-67 nuclear Ag/cells in Breast cancer specimen by Immune stain"
          },
          {
            "code": "83052-1",
            "display": "PD-L1 by clone 22C3 [Presence] in Tissue by Immune stain"
          },
          {
            "code": "83055-4",
            "display": "PD-L1 by clone 28-8 [Presence] in Tissue by Immune stain"
          },
          {
            "code": "83057-0",
            "display": "PD-L1 by clone SP142 [Presence] in Tissue by Immune stain"
          },
          {
            "code": "81691-8",
            "display": "MLH-1 Ag [Presence] in Cancer specimen by Immune stain"
          },
          {
            "code": "81692-6",
            "display": "MSH-2 Ag [Presence] in Cancer specimen by Immune stain"
          },
          {
            "code": "81693-4",
            "display": "MSH-6 Ag [Presence] in Cancer specimen by Immune stain"
          },
          {
            "code": "81694-2",
            "display": "PMS2 Ag [Presence] in Cancer specimen by Immune stain"
          },
          {
            "code": "14229-9",
            "display": "P53 protein Ag [Presence] in Tissue by Immune stain"
          },
          {
            "code": "47303-3",
            "display": "Anaplastic lymphoma kinase Ag [Presence] in Tissue by Immune stain"
          },
          {
            "code": "47021-1",
            "display": "CDX2 Ag [Presence] in Tissue by Immune stain"
          },
          {
            "code": "73910-2",
            "display": "PAX8 Ag [Presence] in Tissue by Immune stain"
          },
          {
            "code": "48677-9",
            "display": "Cancer Ag 125 [Presence] in Tissue by Immune stain"
          }
        ]
      }
    ]
  }
}