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Narrative

Note: links and images are rebased to the (stated) source

Source1

{
  "resourceType": "Observation",
  "id": "PatientKimMusterperson-MolecularPathologyInterpret-0a-Her2neu",
  "meta": {
    "profile": [
      "https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/StructureDefinition/mii-pr-mtb-immunohistochemistry|2027.0.0-ballot.1"
    ]
  },
  "text": {
    "status": "generated",
    "div": "<!-- snip (see above) -->"
  },
  "status": "final",
  "category": [
    {
      "coding": [
        {
          "system": "http://terminology.hl7.org/CodeSystem/observation-category",
          "code": "laboratory"
        }
      ]
    },
    {
      "coding": [
        {
          "system": "http://hl7.org/fhir/uv/genomics-reporting/CodeSystem/tbd-codes-cs",
          "code": "biomarker-category"
        }
      ]
    }
  ],
  "code": {
    "coding": [
      {
        "system": "http://loinc.org",
        "code": "48676-1",
        "display": "HER2 Ag [Interpretation] in Tissue"
      },
      {
        "system": "http://snomed.info/sct",
        "code": "1234806008",
        "display": "Observation using immunohistochemistry (observable entity)"
      }
    ]
  },
  "subject": {
    "reference": "Patient/PatientKimMusterperson"
  },
  "valueCodeableConcept": {
    "coding": [
      {
        "system": "http://snomed.info/sct",
        "code": "1381317004",
        "display": "Human epidermal growth factor receptor 2 low"
      }
    ],
    "text": "HER2-low (IHC 2+/ISH negative)"
  },
  "specimen": {
    "reference": "Specimen/PatientKimMusterperson-AscitesSpecimen-2"
  },
  "component": [
    {
      "code": {
        "coding": [
          {
            "system": "http://loinc.org",
            "code": "48018-6",
            "display": "Gene studied [ID]"
          }
        ]
      },
      "valueCodeableConcept": {
        "coding": [
          {
            "system": "http://www.genenames.org/geneId",
            "code": "HGNC:3430",
            "display": "ERBB2"
          }
        ]
      }
    }
  ]
}