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Source1

{
  "resourceType": "Observation",
  "id": "PatientKimMusterperson-MolecularPathologyObservation-7-p53",
  "meta": {
    "profile": [
      "https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/StructureDefinition/mii-pr-mtb-immunohistochemistry|2026.0.0"
    ]
  },
  "code": {
    "coding": [
      {
        "code": "14229-9",
        "system": "http://loinc.org",
        "display": "P53 protein Ag [Presence] in Tissue by Immune stain"
      },
      {
        "code": "1234806008",
        "system": "http://snomed.info/sct",
        "display": "Observation using immunohistochemistry (observable entity)"
      }
    ]
  },
  "valueCodeableConcept": {
    "coding": [
      {
        "code": "LA6576-8",
        "system": "http://loinc.org",
        "display": "Positive"
      }
    ],
    "text": "Kräftige nukleäre Überexpression von p53"
  },
  "category": [
    {
      "coding": [
        {
          "system": "http://terminology.hl7.org/CodeSystem/observation-category",
          "code": "laboratory"
        }
      ]
    },
    {
      "coding": [
        {
          "system": "http://hl7.org/fhir/uv/genomics-reporting/CodeSystem/tbd-codes-cs",
          "code": "biomarker-category"
        }
      ]
    }
  ],
  "status": "final",
  "subject": {
    "reference": "Patient/PatientKimMusterperson"
  },
  "specimen": {
    "reference": "Specimen/PatientKimMusterperson-AscitesSpecimen-2"
  }
}