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Source1

{
  "resourceType": "Observation",
  "id": "PatientKimMusterperson-MolecularPathologyObs-FISH-0a-Her2neu-",
  "meta": {
    "profile": [
      "https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/StructureDefinition/mii-pr-mtb-insituhybridization-her2|2026.0.0"
    ]
  },
  "category": [
    {
      "coding": [
        {
          "system": "http://terminology.hl7.org/CodeSystem/observation-category",
          "code": "laboratory"
        }
      ]
    },
    {
      "coding": [
        {
          "system": "http://hl7.org/fhir/uv/genomics-reporting/CodeSystem/tbd-codes-cs",
          "code": "biomarker-category"
        }
      ]
    }
  ],
  "code": {
    "coding": [
      {
        "code": "49683-6",
        "system": "http://loinc.org",
        "display": "ERBB2 gene copy number/Chromosome 17 copy number in Tissue by FISH"
      },
      {
        "code": "51864006",
        "system": "http://snomed.info/sct",
        "display": "Nucleic acid hybridization, function (observable entity)"
      }
    ]
  },
  "valueRatio": {
    "numerator": {
      "value": 1.2
    },
    "denominator": {
      "value": 1
    }
  },
  "interpretation": [
    {
      "coding": [
        {
          "code": "260385009",
          "system": "http://snomed.info/sct",
          "display": "Negative (qualifier value)"
        }
      ]
    }
  ],
  "component": [
    {
      "valueQuantity": {
        "unit": "#",
        "value": 2.4
      },
      "code": {
        "coding": [
          {
            "code": "74860-8",
            "system": "http://loinc.org",
            "display": "ERBB2 gene copy number/nucleus in Tissue by FISH"
          }
        ]
      }
    },
    {
      "valueQuantity": {
        "unit": "#",
        "value": 2
      },
      "code": {
        "coding": [
          {
            "code": "74861-6",
            "system": "http://loinc.org",
            "display": "Chromosome 17 copy number/nucleus in Tissue by FISH"
          }
        ]
      }
    },
    {
      "valueQuantity": {
        "unit": "#",
        "value": 50
      },
      "code": {
        "coding": [
          {
            "code": "62361-1",
            "system": "http://loinc.org",
            "display": "Cells counted [#]"
          }
        ]
      }
    }
  ],
  "method": {
    "coding": [
      {
        "code": "1303773004",
        "system": "http://snomed.info/sct",
        "display": "Fluorescence in situ hybridization technique (qualifier value)"
      }
    ]
  },
  "status": "final",
  "subject": {
    "reference": "Patient/PatientKimMusterperson"
  },
  "specimen": {
    "reference": "Specimen/PatientKimMusterperson-AscitesSpecimen-2"
  }
}