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Source1

{
  "resourceType": "Specimen",
  "id": "OrganoidLunge",
  "meta": {
    "profile": [
      "https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/mii-pr-biobank-zellinie-organoid"
    ]
  },
  "type": {
    "coding": [
      {
        "system": "http://snomed.info/sct",
        "code": "123038009",
        "display": "Specimen (specimen)"
      },
      {
        "system": "https://fhir.bbmri-eric.eu/fhir/CodeSystem/miabis-detailed-samply-type-cs",
        "code": "Organoid",
        "display": "Organoids"
      }
    ]
  },
  "container": [
    {
      "specimenQuantity": {
        "system": "http://unitsofmeasure.org",
        "value": 1,
        "code": "ml",
        "unit": "ml"
      },
      "type": {
        "coding": [
          {
            "code": "83059008",
            "system": "http://snomed.info/sct",
            "display": "Tube, device (physical object)"
          }
        ]
      }
    }
  ],
  "extension": [
    {
      "url": "https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/mii-ex-biobank-kulturprotokoll",
      "valueReference": {
        "reference": "DocumentReference/Kulturprotokoll"
      }
    },
    {
      "extension": [
        {
          "url": "artDerModifikation",
          "valueCodeableConcept": {
            "coding": [
              {
                "code": "CLO:0037375",
                "system": "http://purl.obolibrary.org/obo/clo.owl",
                "display": "derived from cell with knockout gene"
              }
            ]
          }
        },
        {
          "url": "zielGen",
          "valueCoding": {
            "code": "TP53",
            "system": "http://www.genenames.org",
            "display": "tumor protein p53"
          }
        },
        {
          "url": "protokoll",
          "valueReference": {
            "reference": "DocumentReference/ProtocolCRISPRTP53"
          }
        }
      ],
      "url": "https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/mii-ex-biobank-modifikationen"
    },
    {
      "url": "https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/mii-ex-biobank-anzahl-passagen",
      "valueInteger": 3
    }
  ],
  "processing": [
    {
      "extension": [
        {
          "valueRange": {
            "low": {
              "system": "http://unitsofmeasure.org",
              "code": "Cel",
              "unit": "°C",
              "value": 37
            },
            "high": {
              "system": "http://unitsofmeasure.org",
              "code": "Cel",
              "unit": "°C",
              "value": 37
            }
          },
          "url": "https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/Temperaturbedingungen"
        }
      ],
      "procedure": {
        "coding": [
          {
            "system": "http://snomed.info/sct",
            "code": "1186936003",
            "display": "Storage of specimen (procedure)"
          }
        ]
      },
      "timePeriod": {
        "start": "2018-06-20T10:00:00+01:00",
        "end": "2018-06-27T10:00:00+01:00"
      }
    }
  ],
  "parent": [
    {
      "reference": "Specimen/MusterprobeGewebe"
    }
  ],
  "identifier": [
    {
      "system": "https://biobank.uk-musterstadt.de/fhir/sid/proben",
      "value": "6789-ORG-1"
    }
  ],
  "status": "available",
  "subject": {
    "reference": "Patient/mii-exa-test-data-patient-1"
  },
  "collection": {
    "collectedDateTime": "2018-06-08T15:34:00+01:00"
  }
}