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Source1

{
  "resourceType": "Bundle",
  "id": "752",
  "type": "transaction",
  "entry": [
    {
      "fullUrl": "http://example.com/Patient/Patient-identifier-1",
      "resource": {
        "resourceType": "Patient",
        "id": "Patient-identifier-1",
        "identifier": [
          {
            "type": {
              "coding": [
                {
                  "system": "https://www.cancercoreeurope.eu/fhir/core/CodeSystem/PseudonymTypeCS",
                  "code": "Local"
                }
              ]
            },
            "value": "GR_VDC_1"
          }
        ],
        "gender": "male",
        "birthDate": "1980-01-01"
      },
      "request": {
        "method": "PUT",
        "url": "Patient/Patient-identifier-1"
      }
    },
    {
      "fullUrl": "http://example.com/Specimen/Sample-identifier-1",
      "resource": {
        "resourceType": "Specimen",
        "id": "Sample-identifier-1",
        "type": {
          "coding": [
            {
              "system": "https://fhir.bbmri.de/CodeSystem/SampleMaterialType",
              "code": "tumor-tissue-ffpe"
            }
          ]
        },
        "subject": {
          "reference": "Patient/Patient-identifier-1"
        },
        "collection": {
          "collectedDateTime": "2021-01-01"
        }
      },
      "request": {
        "method": "PUT",
        "url": "Specimen/Sample-identifier-1"
      }
    },
    {
      "fullUrl": "http://example.com/Condition/Condition-identifier-1",
      "resource": {
        "resourceType": "Condition",
        "id": "Condition-identifier-1",
        "code": {
          "coding": [
            {
              "system": "http://fhir.de/CodeSystem/bfarm/icd-10-gm",
              "version": "2004",
              "code": "C34.0"
            }
          ]
        },
        "bodySite": [
          {
            "coding": [
              {
                "system": "urn:oid:2.16.840.1.113883.6.43.1",
                "version": "31",
                "code": "C34.0"
              },
              {
                "system": "https://www.cancercoreeurope.eu/fhir/core/CodeSystem/SitelocationCS",
                "code": "L"
              }
            ]
          }
        ],
        "subject": {
          "reference": "Patient/Patient-identifier-1"
        },
        "onsetDateTime": "2021-03-12",
        "recordedDate": "2022-03-12"
      },
      "request": {
        "method": "PUT",
        "url": "Condition/Condition-identifier-1"
      }
    },
    {
      "fullUrl": "http://example.com/Observation/Histology-identifier-1",
      "resource": {
        "resourceType": "Observation",
        "id": "Histology-identifier-1",
        "subject": {
          "reference": "Patient/Patient-identifier-1"
        },
        "focus": [
          {
            "reference": "Condition/Condition-identifier-1"
          }
        ],
        "effectiveDateTime": "2021-02-02",
        "valueCodeableConcept": {
          "coding": [
            {
              "system": "urn:oid:2.16.840.1.113883.6.43.1",
              "version": "31",
              "code": "8140/3"
            }
          ]
        }
      },
      "request": {
        "method": "PUT",
        "url": "Observation/Histology-identifier-1"
      }
    },
    {
      "fullUrl": "http://example.com/Procedure/Operation-identifier-1",
      "resource": {
        "resourceType": "Procedure",
        "id": "Operation-identifier-1",
        "category": {
          "coding": [
            {
              "system": "https://www.cancercoreeurope.eu/fhir/core/CodeSystem/SYSTTherapyTypeCS",
              "code": "OP",
              "display": "Operation"
            }
          ]
        },
        "subject": {
          "reference": "Patient/Patient-identifier-1"
        },
        "performedDateTime": "2021-04-01",
        "reasonReference": [
          {
            "reference": "Condition/Condition-identifier-1"
          }
        ]
      },
      "request": {
        "method": "PUT",
        "url": "Procedure/Operation-identifier-1"
      }
    },
    {
      "fullUrl": "http://example.com/Procedure/Radiation-identifier-1",
      "resource": {
        "resourceType": "Procedure",
        "id": "Radiation-identifier-1",
        "category": {
          "coding": [
            {
              "system": "https://www.cancercoreeurope.eu/fhir/core/CodeSystem/SYSTTherapyTypeCS",
              "code": "ST",
              "display": "Radiotherapy"
            }
          ]
        },
        "subject": {
          "reference": "Patient/Patient-identifier-1"
        },
        "performedPeriod": {
          "start": "2021-04-10",
          "end": "2021-04-12"
        },
        "reasonReference": [
          {
            "reference": "Condition/Condition-identifier-1"
          }
        ]
      },
      "request": {
        "method": "PUT",
        "url": "Procedure/Radiation-identifier-1"
      }
    },
    {
      "fullUrl": "http://example.com/MedicationStatement/SystemicTherapy-identifier-1",
      "resource": {
        "resourceType": "MedicationStatement",
        "id": "SystemicTherapy-identifier-1",
        "category": {
          "coding": [
            {
              "system": "https://www.cancercoreeurope.eu/fhir/core/CodeSystem/SYSTTherapyTypeCS",
              "code": "CH"
            }
          ]
        },
        "subject": {
          "reference": "Patient/Patient-identifier-1"
        },
        "effectivePeriod": {
          "start": "2021-06-12",
          "end": "2021-06-21"
        },
        "reasonReference": [
          {
            "reference": "Condition/Condition-identifier-1"
          }
        ]
      },
      "request": {
        "method": "PUT",
        "url": "MedicationStatement/SystemicTherapy-identifier-1"
      }
    }
  ]
}